ライフサイエンスコーパス: complexity

1 effective characterization of transcriptome complexity.

2 ions without consideration of their solution complexity.

3 d daringness, IQ and self-reported cognitive complexity.

4 hey are limited by the lack of physiological complexity.

5 facilitating the evolution of morphological complexity.

6 due to poor implementation leading to added complexity.

7 likely to entirely remove the upper bound on complexity.

8 ification because of their size and sequence complexity.

9 rs have taken the pathway to increased group complexity.

10 challenging to engineer due to its size and complexity.

11 or drug-like properties as well as synthetic complexity.

12 n processing was affected by low-level scene complexity.

13 rved two hand actions that differed in motor complexity.

14 n plasma membranes with higher compositional complexity.

15 ghly challenging because of their structural complexity.

16 stically reduces biodiversity and ecological complexity.

17 ger similar responses, adding a new level of complexity.

18 , with reduced elasticity and organizational complexity.

19 iche density increase with three-dimensional complexity.

20 the increasing homogenization of ecological complexity.

21 plored the effects of manipulations in motor complexity.

22 formance, although, at the cost of increased complexity.

23 of the particle-level structure and chemical complexity.

24 ABC) DLBCL profile, HGBCL, NOS, high genetic complexity, 1q21-q44 gains, 2p16/REL gains/amplification

25 upra-regular grammars of different levels of complexity: a context-free grammar generating sequences

26 ficity, a significantly reduced chromatogram complexity, allows for shorter analysis times, and simpl

27 We show through complexity analysis and experiments that our implementat

28 and imaging have revealed individual patient complexities and exposed the inherent limitations of gen

29 However, there are complexities and manifest limitations inherent in transl

30 framework for explaining variation in molar complexity and a means for testing developmental hypothe

31 as juvenile bird skulls have a morphological complexity and anisomerism more similar to those of non-

32 protein N-glycome profiling revealed reduced complexity and branching.

33 Recent research highlights the complexity and broad range of functions that these alarm

34 In addition to reducing model complexity and discovering key biomarkers, feature selec

35 Overall, our study highlights the impact, complexity and dynamic nature of 3D chromatin architectu

36 Attributed to the unique topological complexity and elegant beauty, Borromean systems are att

37 This failure might reflect disease complexity and heterogeneity, as well as social and econ

38 natural products with impressive structural complexity and high potential as drug candidates.

39 s on glycoscience, is challenging due to its complexity and intrinsic side reactions.

40 study and to delineate, owing to its lineage complexity and lack of a concise genetic definition.

41 hat have contributed to mitochondrial genome complexity and might cause a putative barcoding paradox

42 ides a tractable solution to reduce the time complexity and physical layer costs of quantum computers

43 The complexity and principles of these regulatory networks a

44 lution structural analyses has revealed more complexity and promiscuity in the protein interactions d

45 DNA methylation that may shape transcriptome complexity and proteome specificity in developing soybea

46 oited in living systems to create functional complexity and represents a powerful strategy for constr

47 conserved pathways that regulate structural complexity and reveal the influence of the myocardial tr

48 The cellular complexity and scale of the early liver have constrained

49 e puzzling aspects of biology, including the complexity and stability of living systems.

50 As organisations change in size, complexity and structure, the system dynamics also chang

51 Moreover, the genome complexity and sub-tropical to temperate growing climate

52 t innate immune responses within the natural complexity and the full cellular repertoire of human nas

53 f a large-scale LIP into sub-problems of low complexity and the fusion of the sub-problem solutions t

54 ability of such data is limited due to assay complexity and the resolution thereof is appreciably low

55 omics to the clinic has been hampered by its complexity and the substantial time and human resources

56 The protocols differed in library complexity and their ability to detect cell-type markers

57 among power consumption, cost, computational complexity, and accuracy.

58 ctions for the rapid generation of molecular complexity, and guidance in the structure revision of ol

59 challenges due to their large genome sizes, complexity, and high chromosome numbers.

60 latent class analysis of diabetes duration, complexity, and intensity-of-care variables, versus wome

61 the BECTS patients appears to exhibit lower complexity, and these nonlinear measures may potentially

62 far more non-coding DNA, greater regulatory complexity, and thousands of fold more protein synthesis

63 ese promoters, regulatory networks of higher complexity are assembled, such as logic AND gates and IM

64 ical mechanisms leading to their geometrical complexity are still puzzling, especially for nonuniform

65 ng multiscale, multiphysics modeling of this complexity, are fueled by the data and, in turn, guide d

66 This structural complexity arises from the substantial variability in th

67 analyzing patterns in ecosystem engineering complexity as a result of the extinction drivers.

68 Recent work has exposed its cognitive complexity, as well as its unexpected reliance on portio

69 but these techniques do not consider all the complexities associated with B cell diversification such

70 ders, while revealing significant biological complexities associated with GRIN2A developmental and ep

71 Due to complexities associated with imaging 3D distribution fun

72 ductor can substantially reduce the cost and complexity associated with utilizing crystalline materia

73 ks provide a model of tractable evolutionary complexity at the genomic level.

74 the study, with similar annual increases in complexity before (2% versus 3%; P=0.107) and after (3%

75 o accommodate enzyme mechanisms of arbitrary complexity beyond the conventional Michaelis-Menten sche

76 benefits in terms of reduced model size and complexity, but here we argue that coarse-grained data i

77 enylation (APA) contributes to transcriptome complexity by generating mRNA isoforms with varying 3' U

78 However, the added setup complexity caused by electrodes in the system impedes ef

79 Despite their complexity, cells have evolved mechanisms to precisely c

80 This complexity, combined with difficulty in measuring transc

81 UT1 inputs also show enhanced nanostructural complexity compared with those receiving VGLUT2 inputs,

82 Various levels of complexity constitute the genetic basis, including 1) de

83 redict well, despite the lack of an explicit complexity control during training, such as an explicit

84 ontrol, the informed consent model, protocol complexity, data collection, and implementation integrit

85 r processing and managing the resultant high-complexity datasets.

86 e secondary structure tendencies as sequence complexity decreases.

87 Complexity, defined as the number of stable AF reentrant

88 tivity produce contrasting patterns of molar complexity depending on diet.

89 onal models that capture the full measure of complexity displayed by ion channel function and the low

90 hological changes, is hampered by structural complexity distinctive from images and text.

91 High-complexity DNA barcoding and mathematical modeling indic

92 ous work established that the C-terminal low-complexity domain (LCD) of hnRNPA2 fibrillizes under str

93 ty for chromatin(5,6), while an adjacent low-complexity domain (LCD) promotes LEM2 phase separation.

94 cognition motifs (RRMs) and a C-terminal low-complexity domain, sometimes referred to as a "prion-rel

95 ispersal, cultural adaptations and political complexity during the later stages of the pre-Columbian

96 proposed solution evaluates the reduced time complexity equivalent of a reference quantum circuit.

97 However, formulation complexities, especially for multiantibody deliveries, l

98 Despite HF syndrome complexities, evidence of significant sympathetic overac

99 sis of myeloid transformation and how clonal complexity evolves with disease progression.

100 However, due to its size and complexity, expression of the full-length protein has be

101 few years, however, highlight the intrinsic complexities faced by drug developers pursuing histology

102 molecular interactions of different type and complexity for a given material in the wide pressure-vol

103 re of metastatic lesion formation introduces complexity for both early detection and the study of met

104 is able to efficiently enhance architectural complexity for calix[4]resorcinarene-containing metallo-

105 field toward algorithms with nonexponential complexity for correlated quantum matter with applicatio

106 the mathematical formulation of biocultural complexity, formulas were derived to measure the specifi

107 by biotic and abiotic processes and range in complexity from low molecular mass natural halocarbons (

108 werful means of rapidly leveraging molecular complexity from simple feedstocks.

109 The complexity-generating photocatalytic process also provid

110 uted over large brain volumes(5-7), and this complexity has hindered attempts to probe the function o

111 This complexity has prompted attempts to develop a precision

112 This complexity has resulted in conflicting evidence and opin

113 domain "interkinase region" has low sequence complexity, has high proline content, and lacks predicte

114 nderstood is if molar shape, or specifically complexity (i.e., the number of cusps, crests), can be e

115 ps that lack quantitative results or by high complexity immunoassays that are time- and labor-intensi

116 Poor locus resolution and high genetic complexity impede variant discovery.

117 completed two surgery simulations of similar complexities in a hot and in a normothermic operating ro

118 ructural scaffold allow for the emergence of complexity in a fundamental biological process.

119 ity in microarray fluorescence intensity and complexity in branched glycan structures.

120 systems, comment on PC signature, address PC complexity in fluids, and outline challenges associated

121 is a method to study region-specific protein complexity in primary cells and tissue samples.

122 In alloys, compositional complexity in the passivating oxide(s) and underlying me

123 seq (scRNA-seq) data to shed light on tissue complexity including the number of cell types and transc

124 Technical complexity increased over time as evidenced by increases

125 While technical complexity increased over time, post-operative survival

126 urther evidence that the model's substantial complexity informs our understanding of false memories o

127 y that is singular in its origin, cyclicity, complexity, instability, perpetuity, and breadth of clin

128 millennia) re-assembly of degraded ecosystem complexity integrating interaction network and evolution

129 such integration by offloading the hardware complexity into advanced signal processing techniques th

130 indings suggest that the processing of motor complexity involves not only M1 but also pars operculari

131 usly unrecognized biological and therapeutic complexity is emerging.

132 Additional complexity is introduced in differentiating multimeric G

133 However, as more complexity is introduced to built environments, we must

134 The evolution of complexity is one of the most fascinating and challengin

135 ve been described but their algorithmic time complexity is quadratic and their practical use requires

136 mplicons is characterized by high structural complexity, lacks key local enhancers, and instead conta

137 However, human brain sampling complexities limit the explanatory power of brain-relate

138 ncrease in metazoan diversity and ecological complexity, marking the inception of the Cambrian Explos

139 The results also revealed that the degree of complexity matching that occurred between pairs remained

140 al enrichment steps will be required in high complexity matrices such as serum.

141 Our results suggest increasing landscape complexity may mitigate pest populations and insecticide

142 To reduce the complexity, model systems containing starch, gluten and/

143 The biological complexities of chemoradiotherapy-induced OM involve int

144 fever or dengue shock syndrome; however, the complexities of DENV immunopathogenesis remain controver

145 This direct correlation unravels one of the complexities of exocytosis.

146 This highlights the complexities of interaction between the AIP and PKA path

147 simulated datasets may not reflect the real complexities of metagenomic samples and the estimated as

148 help guide health-care providers through the complexities of non-surgical management of knee OA.

149 However, complexities of selection on MHC genes are simultaneousl

150 ee die-off has not been evaluated due to the complexities of surveying and precisely measuring large

151 ts across multiple disciplines discussed the complexities of the EVALI outbreak, identified research

152 ive probability bounds that are based on the complexities of the inputs as well as the outputs, rathe

153 well as the outputs, rather than just on the complexities of the outputs.

154 r proper somatic stem cell function, but the complexities of the stem cell response to increases in d

155 behaviors and unprecedented increases in the complexities of tissue mechanics and functions.

156 found that stroke patients in the SLSR had a complexity of acute impairments, of which limb motor def

157 a neural network to reduce the computational complexity of an intracellular signaling mechanistic mod

158 Our data highlight the complexity of arbovirus mutation-fitness dynamics and su

159 strates of a KDAC is complicated both by the complexity of assaying relevant activity and by the non-

160 The complexity of biological systems is encoded in gene regu

161 Collectively, the cellular complexity of brain-on-a-chip systems intrinsically deve

162 y used by viruses to increase the volume and complexity of capsids and would provide a new approach t

163 Complexity of cell-type composition has created much ske

164 To this end, here we sought to reduce the complexity of cellular PP2A holoenzymes.

165 These findings reveal the complexity of cellular responses to MDM2 and MDMX and su

166 The structural complexity of composite biomaterials and biomineralized

167 The complexity of coral-reef ecosystems makes it challenging

168 We propose that the complexity of cortical circuits is generated by phylogen

169 ogy to the wider scientific community is the complexity of data analysis.

170 However, the rapid growth in complexity of data from these assays has outpaced our ab

171 behavioral analyses therefore reveal further complexity of dopaminergic reinforcement circuits betwee

172 expression gradually builds the identity and complexity of each tissue and organ system(1).

173 ect prey population size), and highlight the complexity of each transition.

174 The greater complexity of eukaryotes is linked with larger genomes a

175 roma is multi-faceted, which illustrates the complexity of exploring features of the TME as isolated

176 However, due to the greater complexity of genome graphs relative to linear genomes,

177 However, the sheer volume and complexity of genomic data presents a challenge to inter

178 Regardless of the strategy, the complexity of global supply chains will magnify losses b

179 These options collectively minimize the complexity of glucagon delivery and enable its applicati

180 on of GPe neuron classes and illustrates the complexity of GPe neurons in adult mice.

181 proach for quantifying 3-dimensional spatial complexity of grayscale patterns on late gadolinium enha

182 Growing evidence highlights the complexity of IgA-inducing pathways and the functional i

183 We sought to allow description of the complexity of IgE, IgG(4), and IgG epitope recognition a

184 organism Scenedesmus obliquus to capture the complexity of interacting environmental stressors, inclu

185 re among the NCLDVs that likely reflects the complexity of its infection process and may help explain

186 view, we focus on the definition of sequence complexity of LCRs and their connection with structure.

187 umor-associated macrophages (TAM) typify the complexity of macrophage function in cancer.

188 e diversity of HLA alleles (>20,000) and the complexity of many pathogen genomes.

189 l-defined nanostructures, leveraging pathway complexity of molecular disorder to order transition whi

190 topics are discussed according to increasing complexity of molecular representations.

191 Importantly, the complexity of molecular target interactions, such as pro

192 The structural and functional complexity of multicellular biological systems, such as

193 the antenna circuits determines the level of complexity of olfactory processing in the downstream neu

194 nd demography, but also the spatial-temporal complexity of population-level movement patterns.

195 tive behaviour is necessary to cope with the complexity of practice.

196 Adding to the genetic complexity of PXE are PXE-like phenotypes caused by path

197 In conclusion, our work sheds light on the complexity of QDR and provides comprehensive understandi

198 More empirical explorations of how the complexity of real landscapes shapes the ecological and

199 mospheric aerosols, retain the compositional complexity of real-world samples.

200 the plasma membrane, our findings reveal the complexity of recruitment mechanisms that need to be coo

201 s are underpinned by the growth and physical complexity of reef-forming corals.

202 Thus, nano-COP unveils the organizational complexity of RNA processing.

203 ting the increased number of submissions and complexity of sequences.

204 vement variability were used to quantify the complexity of SIB.

205 nd, with large angular variations due to the complexity of speech; 2) a longer distance, ~1 m, where

206 In the era of global surgery and increasing complexity of surgical innovation, this study highlights

207 Due to the complexity of TCM, changes in metabolites should be inve

208 studies were grouped according to levels of complexity of the BM task employed (first-order, direct

209 scribe antibiotics with bone grafting and as complexity of the bone grafting procedure increases.

210 unction on these systems is dependent on the complexity of the cell culture.

211 NR), small sizes of macromolecules, and high complexity of the cellular environment.

212 ns using miRNA and mRNA sequencing data, the complexity of the change of the correlation coefficients

213 Our study highlights the complexity of the CHIKV genome and describes new systems

214 s, we are able to learn models capturing the complexity of the cryoEM image formation process.

215 Due to the complexity of the crystal structure composed of heavy el

216 inues to be a challenging problem due to the complexity of the data.

217 cultures, repeated NPY treatment reduces the complexity of the dendritic extent of anxiogenic BLA pri

218 nequality may be connected to the increasing complexity of the economy.

219 ification of how the biological and chemical complexity of the environment, combined with their seaso

220 e or constant load conditions because of the complexity of the equipment required for the determinati

221 yntax predictive of the full differentiative complexity of the immune system.

222 just perceptual decision-making based on the complexity of the input.

223 immune mechanisms has been challenged by the complexity of the interactions underlying immune process

224 However, the complexity of the involved data makes its application di

225 lies the substantial genomic and pan-genomic complexity of the LUCA itself.

226 their low solubility, low abundance, and the complexity of the membrane subproteome.

227 te allelic effects in SSc and CD reveals the complexity of the molecular mechanisms by which polymorp

228 The complexity of the parasite-host interactions hampers the

229 e population studies, exposing the depth and complexity of the plasma and serum proteomes.

230 This study underscores the complexity of the relationships between B and T cells in

231 We observe that 1) the dynamic complexity of the relaxation kinetics depends on the num

232 The study highlights the complexity of the risk assessment process in relation to

233 The present study demonstrated the complexity of the root canal microbiome and the "common

234 The complexity of the spatio-temporal dynamics of sea ice ma

235 hin a cell increases progressively, with the complexity of the species indicating their essential rol

236 However, due to the complexity of the system, exacerbated by the diverse set

237 utational modeling revealed that the overall complexity of the systemic inflammatory/immune network w

238 cal approach, align those assumptions to the complexity of the systems under study, and take advantag

239 l system clearance, tumor heterogeneity, and complexity of the tumor microenvironment.

240 Our understanding of how the complexity of the wheat genome influences the distributi

241 lation methods and the unresolved structural complexity of these biological-nanoparticles (sub-100 nm

242 y network analysis enabled us to decrypt the complexity of this huge molecular machine, by identifyin

243 In this study, we increased cellular complexity of traditional (simple) neuronal cultures by

244 bosome profiling revealed an uncharacterized complexity of translation in this archaeon with bacteria

245 nths of age, we examined the spatio-temporal complexity of young children's gaze patterns as they vie

246 Reduced circuit complexity often goes hand-in-hand with higher efficienc

247 We introduce pathway complexity on a multicomponent systems level in chemical

248 of food texture (form, viscosity, structural complexity) on satiety.

249 ins domain swap to increase their structural complexity or functional avidity.

250 the same clone(s), accurately measure clonal complexity, or definitively elucidate the order of mutat

251 ng key improvements over previous designs in complexity, output bitrate, and power consumption.

252 ssues have been constrained in architectural complexity, owing to the limitations of extrusion-based

253 Like other innate human senses, the complexity perception cannot be easily quantified.

254 Liat1 is targeted to the nucleolus by a low-complexity poly-K region within its IDR.

255 Although this complexity poses formidable challenges to understanding

256 Cortical-folding complexity quantified using local gyrification index (LG

257 Further complexity reduction is achieved by confining to a singl

258 Low complexity regions (LCRs) in protein sequences are chara

259 There are multiple definitions for low complexity regions (LCRs) in protein sequences, with all

260 There are multiple definitions for low complexity regions (LCRs) in protein sequences.

261 ly features an N-terminal extension with low-complexity regions.

262 tely one third of cancer patients die due to complexities related to cachexia.

263 Despite the complexity, related lineages produce similar neuron type

264 These discoveries also uncover complexities: Results from experiments with Arabidopsis

265 ternet to perform a high-performance and low-complexity routing in the entangled structure.

266 re of the quantum Internet formulates a high complexity routing space that is hard to explore.

267 future studies, comparable cases of moderate-complexity RRD will be chosen naive to surgeon, surgery,

268 pts associated with the systems thinking and complexity science traditions.

269 ne H,N correlation spectra even in these low complexity sequences.

270 n the subset receiving targeted ablation, AF complexity showed lower values in those in whom AF termi

271 ated with greater apical dendritic branching complexity, spine density, and inhibition, indicative of

272 kers of peripheral MU remodelling (MUP size, complexity, stability).

273 d disease severity in sepsis, as well as the complexity surrounding the benefits of specific interven

274 t microscopic wear with higher roughness and complexity than caused by mineral abrasive-free herbivor

275 merged as fundamental regulators of proteome complexity that regulate stem cell identity and function

276 Due to this complexity, the automated annotation of sphingolipid spe

277 At such extremes of simulated system complexity, the largest stable complex systems would be

278 After adjusting for medical complexity, the mean MIPS score for physicians in the hi

279 Decreased neuronal complexity three months after peripheral immune stimulat

280 represents a minimalist model of sufficient complexity to encompass fundamental biomolecular structu

281 powerful strategy for introducing functional complexity to tertiary alkylamines.

282 bHLH protein interactions, adding a layer of complexity to what was previously known.

283 oducts has proven challenging because of the complexity, transience, and low concentration of many in

284 colonization in vivo Thus, we screened a low-complexity transposon (Tn) mutant library to identify no

285 us is poorly defined due to the low sequence complexity (TTAGGG)n of telomeres that cannot be easily

286 udy demonstrates another level of regulatory complexity underlying the spationumerical regulation of

287 Escherichia coli communities with increasing complexity: uni-, bi-, and multi-directional cross-feedi

288 The overall clinical complexity was statistically greater for those treated a

289 Four datasets with different complexity were compared: (1) data from a cell lysate st

290 how that PSDs exhibit greater nanostructural complexity when part of tripartite synapses, and we prov

291 sticated and interrelated levels of chemical complexity which however have never been defined and cod

292 hensive characterizations of the unicellular complexity, which especially makes sense for studying tu

293 r, eukaryotic genomes exhibit vastly greater complexity, which raises questions not addressed by this

294 lations and increase (p < 0.001) in cortical complexity, which was similar to that observed during wa

295 d volcanic ash leads to significantly higher complexity, while fine sands (130 to 166 um) result in s

296 en sensory systems and behavior, given their complexity with high tractability.

297 erious processes interact with extraordinary complexity within and between organs, and a comprehensiv

298 encounter risk, prey density, and vegetation complexity within their home range, on short-term (seaso

299 enced in discussions of social and cognitive complexity, yet relatively little is known of their soci

300 al morphology displays large variability and complexity, yet the canonical regularities of the cortex