ライフサイエンスコーパス: cone pigment

1 hes activating more than approximately 1% of cone pigment.

2 s correlated with abnormal distribution of a cone pigment.

3 10 weeks and reversed the mislocalization of cone pigment.

4 e could regenerate rod pigment but not green cone pigment.

5 icant increases in mRNA levels for the green cone pigment.

6 e opsin shift between rhodopsin and the blue cone pigment.

7 sms during the evolution of rodent long-wave cone pigments.

8 uous noise with a much higher magnitude from cone pigments.

9 uts primarily from cones with mixed M- and S-cone pigments.

10 Nrl(-/-) mice are conelike and contain only cone pigments.

11 is-retinal, the chromophore of rhodopsin and cone pigments.

12 11-cis-retinal chromophore of rhodopsin and cone pigments.

13 lengths are the lambda(max) of the two mouse cone pigments.

14 this methyl group in the salamander rod and cone pigments.

15 the extent of phosphorylation of unbleached cone pigments.

16 11-cis-retinal chromophore of rhodopsin and cone pigments.

17 l shift between the mouse UV and bovine blue cone pigments.

18 ajor role in the spectral tuning of the SWS1 cone pigments.

19 dulation in avian short-wavelength sensitive cone pigments.

20 iously affecting the operation of the native cone pigments.

21 arhodopsin II formation and decay in rod and cone pigments.

22 gment) and a second near 510 nm [midwave (M)-cone pigment].

23 hosphodiesterase inhibitory subunit gamma to cone pigment, 1:68, was similar to the levels observed f

24 The single substitution in the dolphin LWS cone pigment (292S to 292A) causes a red shift from the

25 On the other hand, with the rhodopsin and UV cone pigments, activation was diminished.

26 ozen sections immunolabeled for the mouse UV-cone pigment and colabeled with PNA.

27 epresents the first example of a dark-active cone pigment and constitutively active cone opsin.

28 f the meta-II state (active conformation) of cone pigment and its higher rate of spontaneous isomeriz

29 results in comparing thermal stability of UV cone pigment and rhodopsin provide insight into molecula

30 (-/-) double knock-out model, trafficking of cone pigments and membrane-associated cone phototransduc

31 sharp contrast to its rod counterpart, bound cone pigments and non-visual receptors.

32 tionship between the properties of mammalian cone pigments and those of mammalian cones is not well u

33 e photopigments, one peaking near 350 nm (UV-cone pigment) and a second near 510 nm [midwave (M)-cone

34 which recognizes chicken rhodopsin and green cone pigment, and by reverse transcription-polymerase ch

35 retching frequencies of rhodopsin, the green cone pigment, and the red cone pigment in H2O (D2O) are

36 dopsin numbering) of the tiger salamander UV cone pigment appears to be trapped in an open conformati

37 mechanisms that enable rapid regeneration of cone pigment are poorly understood.

38 te is not a universal attribute of long-wave cone pigments as generally supposed, and that, depending

39 ility of the chromophore within the deep red cone pigment binding sites.

40 vealed component 2 to be linearly related to cone pigment bleaching, and the hypothesis is proposed t

41 igment belongs to the long-wave subfamily of cone pigments, but its absorption maximum is 508 nm, sim

42 ifts the spectral maxima of the red and blue cone pigments, but not that of the red rod pigment.

43 rt-wave cone opsin (S-opsin) to test whether cone pigment can substitute for the structural and funct

44 Ultraviolet (UV) cone pigments can provide insights into the molecular ev

45 Nrl(-/-) photoreceptors express the mouse UV cone pigment, cone transducin, and cone arrestin in amou

46 Retinal rod and cone pigments consist of an apoprotein, opsin, covalentl

47 Interestingly, the red cone pigment containing the retinal analogue remained ac

48 Cone pigment dissociation therefore contributes to the s

49 the initial rapid regeneration of mouse M/L-cone pigment during dark adaptation, whereas the slower

50 wn that rod arrestin can bind and deactivate cone pigments efficiently, the results suggest that cone

51 type-specific expression of the zebrafish UV cone pigment gene by transient expression of green fluor

52 intercalated gene within the red-green opsin cone pigment gene tandem array on Xq28.

53 some to create the present-day red and green cone pigment genes.

54 visual pigment remains stable in darkness, a cone pigment has some tendency to dissociate spontaneous

55 spontaneous isomerization activity of human cone pigments has long remained a mystery because the ef

56 Differences in properties between rod and cone pigments have been described, such as a 10-fold sho

57 n spectra of recombinant human green and red cone pigments have been obtained to examine the molecula

58 rity of mammalian short-wavelength sensitive cone pigments have shifted their absorption maxima from

59 iff base (SB) linkage, but only UV-sensitive cone pigments have this moiety unprotonated in the dark.

60 odopsin, the green cone pigment, and the red cone pigment in H2O (D2O) are found at 1656 (1623), 1640

61 estion by expressing human or salamander red cone pigment in Xenopus rods, and human rod pigment in X

62 the chromophore to regenerate rhodopsin and cone pigments in vivo.

63 The homology models of seven cone pigments indicate that the deep red cone pigments s

64 The canonical visual cycle for rod and cone pigments involves recycling of their chromophore fr

65 Inactivation of meta II in SWS1 cone pigments is regulated by the primary counterion.

66 However, red cone pigment isomerizes spontaneously 10,000 times more

67 otted to summarise the topography of rod and cone pigment kinetics and descriptive statistics conduct

68 mographic spectral analysis of 294 A1 and A2 cone pigment literature absorption maxima indicates that

69 ith concomitant decreases in levels of green cone pigment mRNA.

70 rates that often have three or four types of cone pigment, new findings from zebrafish are extending

71 cis retinal in solution, suggesting that the cone pigment noise results from isomerization of the ret

72 embrane domain were observed in the X-linked cone pigment of bush babies but not in other primates.

73 The blue-sensitive cone pigments of the SWS2 class cluster into two species

74 This cone-pigment property is long known but has mostly been

75 Thus, IRBP does not accelerate cone pigment regeneration and is not critical for the fu

76 Notably, the rates of cone pigment regeneration by the retina and pigment epit

77 demonstrating the interplay between rod and cone pigment regeneration driven by the retinal pigment

78 designed to keep up with the high demand for cone pigment regeneration in bright light and to preclud

79 used transretinal recordings to evaluate M/L-cone pigment regeneration in isolated retinas and eyecup

80 to underlie the Rpe65-/- phenotype, although cone pigment regeneration may be dependent on a separate

81 This novel interdependence of rod and cone pigment regeneration should be considered when deve

82 slowing of foveal visual acuity recovery and cone pigment regeneration, which are related to each oth

83 The time constants of cone pigment regeneration, which averaged 172 seconds fo

84 ssic RPE-dependent visual cycle to mammalian cone pigment regeneration.

85 chromophore, plays in accelerating mammalian cone pigment regeneration.

86 eloping cone dystrophy caused by inefficient cone pigment regeneration.

87 d functional evidence demonstrates that, for cones, pigment regeneration is supported by the parallel

88 75% of the observed blue shift of the violet cone pigment relative to rhodopsin.

89 sin is 10(4)-fold lower than that of rod and cone pigments, resulting in a very low photon catch and

90 n of rhodopsin numbering) in the dolphin LWS cone pigment results in a blue shift in absorption maxim

91 ssociation, apparently a general property of cone pigments, results in a surprisingly large amount of

92 l and signaling properties of the short-wave cone pigment (S-pigment) contribute to the specialized f

93 uires neither the short-wavelength-sensitive cone pigment [S-pigment or cone opsin (OPN1SW)] nor ence

94 he first transgenic model expressed a murine cone pigment, S-opsin, together with the endogenous rhod

95 ven cone pigments indicate that the deep red cone pigments select 6- s- trans chromophore conformatio

96 e theoretically the hypothesis that deep red cone pigments select a 6- s- trans conformation of the r

97 Diversification of cone pigment spectral sensitivities during evolution is

98 Conversely, non-visual arrestin-2 bound cone pigments, suggesting that it may also regulate phot

99 ied 12 amino acid residues in the human blue cone pigment that might induce the required green-to-blu

100 However, for the red cone pigment, the 9-methyl group of retinal appears to b

101 catfish orthologues of rhodopsin and the red cone pigment-the full complement of retinal opsins in th

102 tants of Siberian hamster ultraviolet (SHUV) cone pigment to explore structural rearrangements that s

103 ing the measured quantal noise of transgenic cone pigment to native human red cones, we obtained a da

104 uction, starting distally, but rhodopsin and cone pigments trafficked normally for more than 2 weeks,

105 lls expressed SV40 T antigen, blue and green cone pigments, transducin, and cone arrestin.

106 vercome this problem by expressing human red cone pigment transgenically in mouse rods in order to ex

107 of retinal from a short-wavelength-sensitive cone pigment (VCOP) in 0.1% dodecyl maltoside using fluo

108 A third type of cone pigment was added to dichromatic retinas, providing

109 G protein-coupled receptor kinase 1, whereas cone pigments were present at reduced levels.

110 hydroxylamine; whereas, the rhodopsin and UV cone pigments were stable.

111 Here we show that rod and cone pigments when present in the same cell produce ligh

112 esponding control cultures regarding the red cone pigment, which was expressed in all cases, and the

113 ly similar residues to those of the marmoset cone pigment with a spectral peak of 543 nm.