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1 n the genus Conus (known as "conotoxins" or "conopeptides").
2 which together define a new P-superfamily of conopeptides.
3  notably different from other Gla-containing conopeptides.
4 onses to hydroxylated versus nonhydroxylated conopeptides and the relative susceptibility of proteins
5                                              Conopeptides are encoded by a few gene superfamilies; he
6 roteins, mainly ion channels, the targets of conopeptides are less well known.
7                                              Conopeptides are neurotoxic peptides in the venom of mar
8 (V)1.2 and that further engineering of micro-conopeptides belonging to the KIIIA group may provide su
9                             The four major A-conopeptide clades defined are consistent with the curre
10                                   A new 23AA conopeptide, conolysin-Mt has potent hemolytic activity
11           Here, we examined a panel of 11 mu-conopeptides for their ability to block rodent Na(V)1.1
12 ed a surprisingly diverse origin of alpha4/4 conopeptides from a single species, Conus bullatus.
13                       By analysing several A-conopeptides from other Conus species recorded in GenBan
14 somally expressed polypeptide chains of four conopeptides from the venoms of Conus gladiator and Conu
15 v(O-TBDMS) was used for the synthesis of the conopeptide gld-V* from Conus gladiator.
16              We have also isolated analogous conopeptides (gld-V and mus-V) containing d-Val instead
17 because (i) they are not constrained as most conopeptides, (ii) they are extremely short in length, (
18 he first example of the new mini-M branch of conopeptides in the M superfamily.
19 at are functionally linked to the targets of conopeptides) is another determinant of the elicited beh
20               Opioid receptor screening of a conopeptide library led to a novel selective kappa-opioi
21                                         This conopeptide, like a previously characterized peptide in
22  selection; the magnitude depends on which A-conopeptide lineage and amino-acid locus is analyzed.
23 ustelinus, conolysin-Mt, we expand the known conopeptide mechanisms to include association with and d
24 inding site for the N-channel-specific omega-conopeptide MVIIA, but also a distinct high-affinity sit
25 istinct high-affinity site for another omega-conopeptide (MVIIC), which affects both N- and P/Q-chann
26                        We identified a small conopeptide of only four amino acids from the venom of C
27                                              Conopeptides possessing the Ser-d-Hyv-Trp motif have bee
28 o-conotoxin KIIIA is representative of micro-conopeptides previously characterized as inhibitors of t
29 nderstanding of the mechanisms by which four conopeptides produce different behaviors in mice.
30                            The 19-amino acid conopeptide (rho-TIA) was shown previously to antagonize
31 esponses to the K-channel antagonist, kappaM-conopeptide RIIIJ (RIIIJ), reliably identified six discr
32               The ability to manipulate a mu-conopeptide's affinity and efficacy, as well as its capa
33                                 More than 90 conopeptide sequences from 11 different Conus species we
34                              The panel of mu-conopeptides should be useful in identifying the functio
35 he venom of Conus purpurascens, is the first conopeptide shown to inhibit the Shaker K(+) channel.
36 C-PrXA is strikingly different from the many conopeptides shown to be nicotinic antagonists; it is mo
37                  In summary, we identified a conopeptide that targets the nociceptor-specific ion cha
38 s might help improve the design of analgesic conopeptides that selectively "avoid" nAChR receptors wh
39 and Conus ferrugineus, define a new class of conopeptides, the conopeptide Y (CPY) family.
40 to help identify the allosteric site for rho-conopeptide TIA, an inverse agonist at this receptor.
41 n and alkylation enables cysteine-containing conopeptides to be ascertained.
42                                         Four conopeptides were initially isolated, gld-V/gld-V'from t
43 ypeptides stabilized by disulfide bonds, and conopeptides, which have no or only one disulfide bond.
44 we have identified a unique single-disulfide conopeptide with a noncompetitive, potentially allosteri
45 eptides provides a guidepost for identifying conopeptides with potentially novel functions.
46 eus, define a new class of conopeptides, the conopeptide Y (CPY) family.
47 rmatic tools, we found the highest number of conopeptides yet discovered in a single Conus specimen,