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1 67 upon APC7 loss localizes predominantly to constitutive heterochromatin.
2 ompanies the establishment of novel loops in constitutive heterochromatin.
3 tion, beyond its accumulation on pericentric constitutive heterochromatin.
4 hromatin interspersed within facultative and constitutive heterochromatin.
5 me2, the latter a repressive modification in constitutive heterochromatin.
6 late lysine 9 of histone H3 (H3K9me) to form constitutive heterochromatin.
7  trimethylation (H3K9me2/3), the hallmark of constitutive heterochromatin.
8 iptional silencing was mediated by canonical constitutive heterochromatin.
9  CDCA7-HELLS chromatin remodeling complex to constitutive heterochromatin.
10 G (H = A, C, or T) and not CG methylation at constitutive heterochromatin.
11  repeat arrays, may lead to the formation of constitutive heterochromatin.
12  Dm0), and, like Lamin, Wash associates with constitutive heterochromatin.
13 rived of canonical telomeres but capped with constitutive heterochromatin.
14 vo establishment of domains with features of constitutive heterochromatin.
15 nuclear organization, especially at sites of constitutive heterochromatin.
16 s the cellular RNAi pathway with assembly of constitutive heterochromatin.
17 ion of histone H4K20, an epigenetic mark for constitutive heterochromatin.
18  dimethylation, separates CEN chromatin from constitutive heterochromatin.
19  to environmental stresses, to nucleation of constitutive heterochromatin.
20 ike those in unexpressed euchromatin and not constitutive heterochromatin.
21  petunia, does not predominantly localise to constitutive heterochromatin.
22 e inactive X and is excluded from regions of constitutive heterochromatin.
23 sgenes are strongly affected by proximity to constitutive heterochromatin.
24 n development is the dramatic remodelling of constitutive heterochromatin, although the functional re
25 of genes reside within regions classified as constitutive heterochromatin and activating influences o
26 s of repetitive DNA organized in the form of constitutive heterochromatin and associated with repress
27 cumulation of the CPC kinase Aurora B within constitutive heterochromatin and hyperphosphorylation of
28 EIN-2 (CDP-2) is required to target HDA-1 to constitutive heterochromatin and is also required for no
29 ated histones are a defining feature of both constitutive heterochromatin and PcG-repressed chromatin
30            In contrast to stably repressive, constitutive heterochromatin and stably active, euchroma
31   Trimethylated H3(K9) marks pericentromeric constitutive heterochromatin and the male Y chromosome,
32 ylated histone H4 that discriminates between constitutive heterochromatin and unexpressed euchromatin
33 ametrical separation between facultative and constitutive heterochromatin, and the organization of RN
34 entally regulated model of PRC1 occupancy at constitutive heterochromatin, and where BMI1 function in
35 g nucleolar organizing regions and repulsive constitutive heterochromatin are major mechanisms to reg
36   In this review we discuss the mechanism of constitutive heterochromatin assembly, its dynamic natur
37 d gene loci and facilitates the formation of constitutive heterochromatin at centromeric and mating-t
38 characterized by a large centrally localized constitutive heterochromatin block and by the presence o
39 us, with one of the alleles localized to the constitutive heterochromatin block and the other one loc
40 matin domains that are localized around this constitutive heterochromatin block.
41  the methyltransferase SET-7) did not impact constitutive heterochromatin but partially rescued the s
42 amins in animals are characterized mostly by constitutive heterochromatin, but association with facul
43                                              Constitutive heterochromatin by contrast is largely HDA1
44  chromosomes, suggesting, surprisingly, that constitutive heterochromatin can self-aggregate without
45 ve X chromosome (Xa), DXZ4 is organized into constitutive heterochromatin characterized by a highly o
46 onal aspects of fHC that distinguish it from constitutive heterochromatin (cHC) and euchromatin (EC)
47 d absence of HP1alpha, HP1beta and HP1gamma, constitutive heterochromatin compartments are normally r
48                           Therefore, the key constitutive heterochromatin determinants can dynamicall
49  transcription of repetitive elements within constitutive heterochromatin domains is required for RNA
50 chromatin assembly, our results suggest that constitutive heterochromatin domains use multiple pathwa
51 asmic transcription sites, nuclear speckles, constitutive heterochromatin domains, mitotic chromosome
52 mportance for the restricted transmission of constitutive heterochromatin during reprogramming and a
53 ximal regions and H3K27me1 is diagnostic for constitutive heterochromatin elsewhere in the barley gen
54 CA7, but not ICF mutants, is concentrated in constitutive heterochromatin foci, and the formation of
55         Our results reveal that emergence of constitutive heterochromatin follows a stereotyped devel
56       We show here that BMI1 is required for constitutive heterochromatin formation and silencing in
57 ification that is best known for its role in constitutive heterochromatin formation and the repressio
58 9 methyltransferase necessary for initiating constitutive heterochromatin formation during early Dros
59 nt with that of BMI1 for H2A(ub) deposition, constitutive heterochromatin formation, and silencing.
60                                              Constitutive heterochromatin gradually self-aggregated a
61 amic fashion with the molecular hallmarks of constitutive heterochromatin, H3K9me3 and H4K20me3.
62 reductions of H3K9me3 and DNA methylation in constitutive heterochromatin have been variously reporte
63                                              Constitutive heterochromatin (HC) is important for maint
64                                           At constitutive heterochromatin, HDA-1 deficient cells disp
65 stone H3 methyltransferase Suv39h1 away from constitutive heterochromatin; however, it does not affec
66 67, but not H3S10ph, rescued the function of constitutive heterochromatin in APC mutant neurons.
67       We found that translocation of BRD4 to constitutive heterochromatin in cells leads to apparent
68 me3) undergoes genome-wide redistribution to constitutive heterochromatin in DCDC- or HP1-deficient m
69 omatin protein 1 (HP1) is a key component of constitutive heterochromatin in Drosophila and is requir
70 pora clarify interactions of facultative and constitutive heterochromatin in eukaryotes.
71 es to the stable association of SUV39H1 with constitutive heterochromatin in human cells.
72 n for chromatin-associated RNA in regulating constitutive heterochromatin in human cells.
73 ever, assumed that the PRC1 is excluded from constitutive heterochromatin in somatic cells based on w
74 romeric repositioning, plus amplification of constitutive heterochromatin in the short arms of the X
75 s boundaries, and initiates the formation of constitutive heterochromatin in yeast.
76 K36 methyltransferase ASH1 and components of constitutive heterochromatin including the H3K9me3-bindi
77 na, and generally display characteristics of constitutive heterochromatin, including late DNA replica
78                                              Constitutive heterochromatin is a largely silent chromos
79                                              Constitutive heterochromatin is a prevalent feature of e
80                                 This loss of constitutive heterochromatin is accompanied by an up-reg
81                                              Constitutive heterochromatin is an important component o
82 ochromatin in differentiated cell types, how constitutive heterochromatin is assembled de novo during
83                        In Neurospora crassa, constitutive heterochromatin is characterized by trimeth
84                                              Constitutive heterochromatin is commonly associated with
85                  During animal reproduction, constitutive heterochromatin is disassembled in gametes
86 particularly sensitive to dCas9-VPR, whereas constitutive heterochromatin is less responsive.
87                                              Constitutive heterochromatin is marked by distinctive hi
88                                        While constitutive heterochromatin is predominantly located wi
89 aled that HP1a binding to methylated H3K9 in constitutive heterochromatin is required to limit contac
90                                              Constitutive heterochromatin is responsible for genome r
91                                              Constitutive heterochromatin is traditionally viewed as
92                                              Constitutive heterochromatin is typically defined by hig
93 istone 3 (H3K9me3), which is the hallmark of constitutive heterochromatin, is however largely unknown
94 36); a site associated with the formation of constitutive heterochromatin, lysine 9 (H3K9); and a sit
95                         Dysregulation of the constitutive heterochromatin machinery (HCM) that silenc
96 s silencing mark is typically imposed by the constitutive heterochromatin machinery (HCM).
97 that IFI16 physically partners with the core constitutive heterochromatin machinery to silence the ke
98 ral mechanism and the core components of the constitutive heterochromatin machinery.
99 h1 known exclusively as a factor involved in constitutive heterochromatin maintenance, actively parti
100  DNA methylation valleys (DMV) harboring the constitutive heterochromatin mark H3K9me3 as well as biv
101 so show a down-regulation of the pericentric constitutive heterochromatin mark, histone H3 trimethyla
102                              Facultative and constitutive heterochromatin marked by H3K27me3 and H3K9
103                Rosette-like stem cells erase constitutive heterochromatin marks and display a primed
104 romatin marks in regions usually occupied by constitutive heterochromatin marks disrupts the 3D genom
105  model organism bearing both facultative and constitutive heterochromatin, Neurospora crassa, to expl
106 In nonmitotic cells, Pdx1 is not observed in constitutive heterochromatin, nucleoli, or most areas co
107 ating heterochromatic regions, including the constitutive heterochromatin on repetitive sequences nea
108  translocations and the addition/deletion of constitutive heterochromatin on two autosomes and the X
109 tor connecting the pluripotency network with constitutive heterochromatin organization in mouse embry
110  methylation levels in vivo demonstrate that constitutive heterochromatin organization is modified in
111 verall, our data reveal another function for constitutive heterochromatin proteins (the establishment
112 e and loss of silencing of reporter genes in constitutive heterochromatin regions.
113     Loss of H4K20me3 and H3K9me3 occurred at constitutive heterochromatin repeats.
114 in B1 and B2 partitioning to facultative and constitutive heterochromatin, respectively, and were ass
115 ands-P, which are similar to facultative and constitutive heterochromatins, respectively.
116          Enforcing precocious acquisition of constitutive heterochromatin results in compromised deve
117  untranscribed gene standards > D4Z4 arrays> constitutive heterochromatin (satellite 2; P < 10(-4) fo
118 mpared the physical properties of a 15.51-kb constitutive heterochromatin segment and a 16.17-kb facu
119                     Overall, facultative and constitutive heterochromatin show both similar and disti
120 16, and Y, which consist of highly condensed constitutive heterochromatin, showed statistically signi
121 artment to the active A-compartment, whereas constitutive heterochromatin shows no significant change
122 t, remain largely repressed, suggesting that constitutive heterochromatin spreading can compensate fo
123 2 inhibition promotes lamina association and constitutive heterochromatin spreading into H3K27me3-mar
124 ch contrasted with the dense compartments of constitutive heterochromatin surrounding the centromeres
125 ching) are no more sensitive than the nearby constitutive heterochromatin that has previously been sh
126 y organisms, repetitive DNA is packaged into constitutive heterochromatin that is marked by di/trimet
127 cing at pericentromeric satellite sequences (constitutive heterochromatin), the maintenance of DNA me
128 omeres of most organisms are embedded within constitutive heterochromatin, the condensed regions of c
129 evaluate the contribution of H3K9-methylated constitutive heterochromatin to 3D genome organization i
130         Yet, it is frequently constrained by constitutive heterochromatin, usually characterized by h
131 actor (TF) PhpC(NF-Y) complex can infiltrate constitutive heterochromatin via its histone-fold domain
132                 Although a large fraction of constitutive heterochromatin was marked by H3K9 methylat
133 netic marks regulating either facultative or constitutive heterochromatin were examined.
134 P1) proteins, which are thought to partition constitutive heterochromatin, were absent from mitotic c
135  is to package such sequences into so-called constitutive heterochromatin, where the dense chromatin
136 his irregularity is particularly striking in constitutive heterochromatin, which has typically been v
137 ding protein 2 (MeCP2) is a key component of constitutive heterochromatin, which is crucial for chrom
138                                Unexpectedly, constitutive heterochromatin, which is generally associa

 
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