ライフサイエンスコーパス: contribution of

1 ange from 7.6 to 27 mug/L with a median risk contribution of 0.0014.

2 We also evaluated the contribution of 18,653 genes in case-control analyses st

3 Our findings demonstrate the important contribution of a tissue-specific protein to the polyQ p

4 STATEMENT This work demonstrates beneficial contributions of a macrophage-mediated response for neur

5 motor cortex and cerebellum, as well as the contribution of abnormal sensorimotor processing.

6 tes required for effective DBS, and thus the contribution of activation of STN neurons to the therape

7 netrance and variable expressivity suggest a contribution of additional genetic lesions to clinical m

8 In this study, we analyzed the contributions of AdeABC and AdeIJK in antibiotic resista

9 In particular, the relative contribution of adult-born (abGC) and mature (mGC) granu

10 Furthermore, the greater contribution of African women to the gene pool compared

11 used a retrospective approach to assess the contributions of age-structure and vital rates to short-

12 is a dearth of information on the potential contribution of agrochemicals to insecticide resistance

13 he cocaine CPP procedure to first define the contributions of alpha(2a)-AR heteroreceptors to stress-

14 We sought to reconcile the clear contribution of androgen receptor (AR) activity that has

15 Here, we examined the contribution of anion channels to cGAMP transfer and ant

16 vide a robust quantification of the relative contributions of anthropogenic, natural, and internally-

17 Our results suggest a contribution of antidromic activation of M1 during STN D

18 ive than the IIV4 vaccines, highlighting the contributions of antigen amount and adjuvant use to VE.

19 s of peptide-MHC binding that can reveal the contributions of any interaction toward stability.

20 tage of a humanized-mouse model to probe the contribution of APOBEC3 mutagenesis to viral evolution.

21 rescence is facilitated by the increase of a contribution of aromatic poly(carboxylic acid)s with hig

22 incess cruise ship outbreak, to quantify the contribution of asymptomatic infections to transmission.

23 The contribution of atoms of the protein residues Met40, Tyr

24 may impact ARD phenotyping and assessment of contribution of atopy to ARD.

25 In this study, we investigated the relative contributions of ATP7A and the metallothioneins MT-I and

26 We assessed the potential functional contributions of B cells via bulk and single-cell RNA se

27 sies relating to the mechanisms and relative contributions of barrier regulation, transendothelial si

28 There is a need to better understand the contribution of basal cell hyperplasia and associated mu

29 ons to global model output, we find that the contribution of BC to potential [INP] relevant to mixed-

30 More understanding of the contribution of biological, genetic, and environmental f

31 also greatly inform our understanding of the contributions of biospecimens (e.g., pubertal hormones),

32 eveal a complex emission mechanism involving contributions of both thermally activated delayed fluore

33 ells (DTCs), it is critical to determine the contribution of bystander effects to the overall respons

34 Yet, the contribution of cancer cell-derived ECM and tumor mechan

35 atches in northern Sweden and quantified the contribution of canopy vegetation to soil CO(2) fluxes a

36 cinoma in all age groups, thus affecting the contribution of carcinoid tumors to overall cancer cases

37 be the mechanisms that might account for the contribution of cardiovascular risk factors to the most

38 2q37.1), we found statistically significant contributions of Cd to smoking-related DNAm.

39 The contribution of CD4(+) T cells to protective or pathogen

40 The contribution of cellular proliferation to viral persiste

41 We examined the contribution of central K(ATP) channels to glucose effec

42 of soil pore space according to the relative contribution of certain size fractions of particles to t

43 lone (E), allowing us to quantify the unique contribution of chemotherapy to CRCI.

44 To assess the contribution of CHIKV replication in skeletal muscle cel

45 taphase will facilitate understanding of the contribution of chromosome segregation errors to the dev

46 hic characteristics and obesity with a minor contribution of chronic comorbid conditions.

47 CI, Raju and Shashikanth et al. examined the contribution of claudin-2 to immune-mediated colitis.

48 We highlight the distinct contributions of coagulopathy, thrombocytopathy and endo

49 The contribution of coding mutations to oncogenesis has been

50 nese ancestry was performed to determine the contributions of coding DNMs to an individual's OFC risk

51 This work demonstrates the contribution of common genetic variation to suicide atte

52 l community assembly, including the relative contributions of competition and cooperation and the eme

53 mstance of conserved synteny to estimate the contribution of complete divergence to the pool of orpha

54 chain shedding unique light on the relative contributions of configurational and conformational impr

55 The exact contribution of congenital cytomegalovirus infection (cC

56 ion methodology (P < 0.05), including in the contribution of contaminant signal.

57 (REM) were used to describe and compare the contribution of contextual effects to the variation in c

58 ned with statistical models, to quantify the contribution of cooling and water supply to the yield be

59 hese findings highlight the underappreciated contribution of coupling motifs in retinal circuitry and

60 Overall, this work highlights the contributions of CR3, C3, and ROS to innate sex bias in

61 ever, there are limited data on the relative contribution of critical steps during antireflux procedu

62 it is difficult to separate out the relative contribution of cutaneous and muscle afferent input to e

63 Considering the important contributions of CXCR4 to B cell development and functio

64 FaceBase 3 now welcomes contributions of data on craniofacial and dental develop

65 anistic basis of seizure initiation, and the contribution of defined neuronal subtypes to seizure pat

66 tDNA is a mix of fragmented alleles, and the contribution of different cancer deposits to ctDNA is la

67 The contribution of different Faddeev components in the norm

68 gain a better understanding of the relative contribution of different PI3K isoforms under homeostati

69 arameters of epidemic spread to estimate the contribution of different transmission routes and determ

70 l variability are complex and the individual contributions of different factors to total phenotypic v

71 main on some fundamental issues, such as the contributions of different regions, constituent fluxes a

72 The sequence-intrinsic contributions of disordered proteins to phase separation

73 However, the contribution of distinct alpha2delta subunits to excitat

74 of DSB, and pave the road to dissecting the contributions of distinct DSB sensors in downstream sign

75 (2020) examine the contributions of distinct paraventricular thalamus (PVT)

76 ng sulphide, resulting in an increase in the contribution of DNRA to NO(3) (-) respiration.

77 However, the contribution of dopamine in dynamic, ecological situatio

78 Here we demonstrate a critical contribution of DRG macrophages, but not those at the ne

79 These data reveal a previously unappreciated contribution of dual TCR cells to the immune repertoire

80 -2 with the immune system and the subsequent contribution of dysfunctional immune responses to diseas

81 The contribution of dyslipidemia and inflammation in atheros

82 The contribution of E449K is both thermodynamic and kinetic.

83 to overall gecko adhesion, but the relative contribution of each depends on the environmental contex

84 ements for Ptf1a in mice, tested the in vivo contribution of each element individually and in combina

85 ted perturbation process to characterize the contribution of each gene to the overall system's robust

86 (PM), but little is known about the relative contribution of each individual species.

87 We review the contribution of each major metabolic pathway to autoimmu

88 The contribution of each mechanism to cutin synthesis and de

89 In order to gain insight into the contribution of each somatostatin to specific nervous sy

90 n the side chain are employed to clarify the contributions of each functional group to contact electr

91 in HEK293 cells, we assessed the pH-sensing contributions of each triad residue in all three recepto

92 cal air quality modeling to characterize the contribution of emissions reductions to ambient ozone co

93 To evaluate the contributions of enhancers/promoters interactions to PEL

94 rtebrate ecoimmunology has been the relative contributions of environmental factors (E), genetic back

95 as been mounting evidence suggesting pivotal contributions of environmental factors and lifestyle cho

96 The contribution of epigenetics in this process remains unkn

97 nter pneumococci, the cellular processes and contribution of epithelial cells to the host response ar

98 framework, which allows us to probe for the contribution of equilibrium fluctuations to phosphorylat

99 By establishing the contribution of erosion as a key driving force behind th

100 rice farming into Indonesia, as well as the contribution of external immigrants in this process.

101 ding with a slope of m (FA+pH) (the combined contribution of FA and FA-induced lowering of pH), as we

102 To test for the potential contributions of feedback modulations on size representa

103 These results imply distinct contributions of FEF and caudate neurons to reward-biase

104 flux, but large uncertainties remain on the contribution of fires and other disturbance fluxes.

105 Appreciating the contributions of Forest Transitions to the sequestering

106 tates to inform assessments of the potential contributions of forests in climate change mitigation as

107 Based on radioisotope (14)C results, the contribution of fossil fuel source PM(1) was 8-24%.

108 The contribution of free-living PA to surgery-induced weight

109 Here, we examined the contribution of G-quadruplex (G4) nucleic acid structure

110 ehavior has provided unique insight into the contribution of gammadelta T cells to barrier immunity.

111 we investigated the individual and combined contributions of GAS1, CDON and BOC to HH-dependent mamm

112 and racial majorities, and equally impactful contributions of gender and racial minorities are less l

113 The contribution of gene-by-environment (GxE) interactions f

114 idate imprinting mechanisms and decipher the contribution of genes to the symptoms of TS and KOS.

115 n immunodeficiency virus (HIV), the relative contribution of genetic background, clinical risk factor

116 derpinnings, particularly with regard to the contribution of genetic factors.

117 n their association with Lynch syndrome, the contribution of genetic risk factors to UC pathogenesis

118 ylation quantitative trait loci revealed the contribution of genetic variation to transcription and D

119 The relative contributions of genetic and environmental factors to va

120 study provides novel insights regarding the contribution of genetics, in combination with known trea

121 iers with mutations in RPGR and quantify the contribution of genotype, genetic modifiers, and XCI to

122 We examine the contributions of geographical and environmental variable

123 otoxicity, it is critical to investigate the contribution of glia to alpha-synuclein aggregation and

124 In this study, the contributions of GRA12 to the molecular pathogenesis of

125 the Society could take action to reduce its contribution of greenhouse gas emissions.

126 a maximum likelihood method to estimate the contribution of GxE to continuous traits taking into acc

127 implications for understanding the relative contributions of HC subtypes in the outer retina.

128 le areas of the visual cortex, with distinct contributions of higher areas to specific aspects of dep

129 Emerging evidence suggests that the contribution of hippocampus to place learning may also u

130 Here, we report that maternal contribution of histone H3.3 assembly complexes can prev

131 ucture and systematic analysis elucidate the contributions of Hoogsten hydrogen bonds, sugar, and pho

132 hus, this model can be used to determine the contribution of host and bacterial factors toward K. pne

133 The contribution of HOX genes' expression to the development

134 bed can be used to test the magnitude of the contribution of identified metabolic pathways to fitness

135 ese unique datasets provide insight into the contribution of IL-10 to the immunological balance neces

136 The contribution of IL-1alpha to oviduct pathology was more

137 been relatively well established, the exact contributions of IL-12, IL-18, and TLRs remain unclear f

138 However, the relative contributions of IL-2 and T cell receptor signaling to t

139 Here we discuss the immense contributions of immigrants to cancer research and the a

140 files of CAV and to determine the respective contribution of immune and nonimmune factors in CAV deve

141 complementation assays, we investigated the contributions of individual 3Bs to replication and the s

142 g C34 as an anti-determinant by studying the contributions of individual bases in the anticodon loop

143 ion is a powerful method for elucidating the contributions of individual cell populations to embryoni

144 on were rigorously analyzed to determine the contributions of individual residues and two 1.5 angstro

145 However, the contributions of individual residues to specificity are

146 quantitative information is known about the contributions of individual RSS positions over the cours

147 The contribution of inflammation to the chronic joint diseas

148 excitation index, a biomarker reflecting the contribution of inhibitory and facilitatory circuits in

149 the IAV of S(net) over 1959-2015, while the contribution of intact land is reduced by more than half

150 This study evaluates contributions of jaw injury and experimental pain sensit

151 amate release that results from an anomalous contribution of L-type Ca(2+) channels to neurotransmitt

152 influenza seasons to estimate the potential contribution of leaky vaccine effect to the observed dec

153 However, contributions of lineage-specific TE insertions to recen

154 Here we dissect the contribution of local dynamics and inputs to cortical pa

155 of the 2,034 sequences revealed an important contribution of local transmission in sustaining the epi

156 Particularly, the contribution of Lon-1 to B. burgdorferi fitness and infe

157 ulmonary blood vessels in lung fibrosis, the contribution of lymphatics to fibrosis is unknown.

158 l differentiation strategies, we dissect the contribution of MAFB to beta-cell development and functi

159 The causal mechanisms and the relative contributions of maternal and fetal genetic effects behi

160 nvironmental microbiology, to understand the contribution of metabolically active bacteria in fundame

161 studies in U.S. cities have highlighted the contribution of methane emissions from natural gas distr

162 of plant C into microbial necromass and the contribution of microbial necromass to SOC, respectively

163 different, and the P-induced decrease in the contribution of microbial residues might be unfavorable

164 The building evidence for the contribution of microbiota to human disease has spurred

165 has been difficult to delineate the specific contribution of microglia to disease.

166 ide food in terms of calories, the essential contribution of micronutrients (vitamins and minerals) t

167 The absolute contribution of migraine with aura to CVD incidence in r

168 ich is conservative, as it only includes the contribution of mineral soils.

169 Here we define the relative contribution of mitochondrial electron transport chain (

170 In this work, we dissect the contributions of modules within the disordered CTT to as

171 temporal unwrapping procedure to assess the contributions of moment-to-moment activity cofluctuation

172 monstrating that a detailed understanding of contribution of motor actions to sensing is needed to un

173 A better understanding of the contribution of mTOR to T-cell fate decisions will ultim

174 To comprehend the contribution of Muc5ac in pancreatic cancer pathology, w

175 significant SNPs for SCS, and quantified the contribution of MY and LACT acting as mediator traits to

176 ng role of Na(V)1.7 and indicated an overall contribution of Na(V)1.9.

177 For many of the contributions of nature, we find differing trends across

178 ional forest inventory plots to describe the contribution of nearly 1.4 trillion trees on forestland

179 The relative contributions of neighborhood food availability and soci

180 The degree of contribution of neural representation and attention to c

181 The contribution of neuroinflammation to the pathogenesis of

182 nduced acute pyelonephritis to determine the contribution of neutrophils and monocytes to resolution

183 Here, we first discuss representative contributions of niche cell types to regulation of neura

184 tive stress, it is important to consider the contribution of NKA inhibition to their cytotoxic effect

185 The contribution of NO(3)(-)/NO(2)(-) to the nitration and n

186 However, the relative contribution of Notch3 expression in tissue versus infil

187 es with varied DHTKD1 expression reveals the contributions of OADH and OGDH to oxidation of 2-oxoadip

188 We also discuss the major contribution of obesity and alcohol to the ten most comm

189 re involved in chromatin compaction, but the contribution of other chromatin proteins, DNA sequence a

190 , Zambia, and Uganda, when compared with the contributions of other factors (such as HIV or aggressiv

191 A key contribution of our work is direct visualization of the

192 The Sr and Ba atoms diminish the contribution of Pb 6s(2) states and decrease the energy

193 d efferocytosis and underscore the important contribution of PE in these major biological processes.I

194 phaltene samples is key to understanding the contribution of photochemically generated dissolved orga

195 However, the relative contributions of plant identity, phenology and soil reso

196 The contribution of poly ribosomes dominates at faster and s

197 ensive genome-wide assays, has confirmed the contribution of polygenic inheritance involving common a

198 i-PyMT) model and highlight the differential contributions of pre- and post-EMT tumor cells in breast

199 immunodeficiency virus; however the relative contributions of pre-ART drug resistance mutations (DRMs

200 We found that the contribution of preparatory neural activity to movement

201 ) in wildfire plumes, including the relative contributions of primary versus secondary sources, has b

202 substrates and the previously unappreciated contribution of protein cofactors to PBP activity.

203 We quantified contributions of protein regions to the ASCC2-ASCC3 inte

204 However, the relative contributions of protein-protein and protein-membrane in

205 be it as signaling platforms or through the contribution of proteins and lipids.

206 ement of the halides, largely neglecting the contribution of protons, on the basis of computed densit

207 unctional categories indicated a significant contribution of regulatory elements to EOC heritability.

208 ma-herpesvirus NECs, the binding free energy contributions of residues displayed from identical posit

209 ween host genetics and viral infections, the contributions of respiratory viral infections to pattern

210 lated, allowing us to dissociate between the contributions of reward and learning to happiness.

211 ever, our knowledge about Munc13-independent contributions of RIM to active zone functions is limited

212 studied, less attention has been paid to the contribution of RNA to LLPS.

213 Our data reveal the contribution of rostral inferior parietal lobule (IPL) r

214 We dissected the particular contributions of sensory-driven versus choice-correlated

215 ss of glycocalyx integrity and highlight the contribution of several proteases, heparanase, and hyalu

216 global shale gas production to constrain the contribution of shale gas emissions to observed atmosphe

217 ion is a multistep process entailing dynamic contribution of SHF-derived ECs to pharyngeal arches, th

218 Dissecting the relative contributions of simulations of AF induction and raw ima

219 These results point to the potential contribution of single-gene CNVs to schizophrenia, indic

220 Here, we assessed the contribution of somatic structural variation (SV) in neu

221 nd that the capacity to predict the combined contribution of species to stability from the sum of the

222 Knowing this and the relative contribution of specific dietary and physical activity b

223 etal-ion binding, quantitatively linking the contributions of specific interactions of metal ions wit

224 to outbreaks, limiting our knowledge of the contribution of sporadic illness to the overall impact o

225 gical models with fractional exponent in the contribution of sub-populations to the incidence rate.

226 id coherence length, to enhance the relative contribution of surface excitations, and suppress hydrod

227 the SVZ after cortical injury, reducing the contribution of SVZ-derived reactive astrocytes to lesio

228 The contribution of terrestrial DOC leaching to the global-s

229 lief, we could detect no significant genomic contribution of the Arabian breed to the Thoroughbred ra

230 Together with an analysis of the contribution of the different inositide phosphate groups

231 The large contribution of the edges to the total release offers op

232 This observational study investigated the contribution of the fecal microbiome to influence host p

233 To unravel the contribution of the immune system to CDC pathogenesis, w

234 Here, we consider the contribution of the individual modification/binding site

235 s to colonize the respiratory tract, but the contribution of the latter is particularly unclear.

236 ypes, and from these genes, we estimated the contribution of the major cell types to the composition

237 Here, we investigated the contribution of the MAPK module MEK5-ERK5 to SCLC growth

238 This task revealed the differential contribution of the NAcC to responding to different type

239 The relative contribution of the peak leaf area and vegetation stress

240 ess of haze development and to calibrate the contribution of the physical and chemical effects on the

241 f N-terminal residues revealed an unexpected contribution of the receptor N terminus to chemokine sig

242 of applicability and confirms the mechanical contribution of the reconstituted AJs.

243 tistical framework for jointly inferring the contribution of the relevant selective and demographic p

244 The contribution of the RLIM-flanking genes to the phenotype

245 ependent conformational changes suggests the contribution of the S1-S4 domain to thermosensing shares

246 controlling signal peptide trimming and the contribution of the T1D inflammatory milieu on these mec

247 lectively, these results indicate a critical contribution of the viral membrane to the stability of t

248 r model, with centering, to assess the joint contributions of the 2 components of the risk-factor exp

249 However, the relative contributions of the ANS and SAN to HRV are not clear, i

250 The joint contributions of the CTL and CTP make Bs-FtsZ, an enzyme

251 r cutting methods allowed us to separate the contributions of the edge- and surface-sourced fibers fr

252 rogenitor cell migration, and the functional contributions of the epicardium to heart formation and c

253 To explore the individual functional contributions of the first (BD1) and second (BD2) bromod

254 Together, these results show that contributions of the immune system are integral for NMJ

255 alth and have implications for understanding contributions of the latter to late life dementia risk.

256 eclinical models have begun to elucidate the contributions of the PFC and its circuitry to depression

257 al approaches have described the overarching contributions of the PM network, but less is known about

258 =pyridinium and ammonium, we can isolate the contributions of the pyrazinium-based orbitals in the ba

259 states to ensure accurate assessments of the contributions of the sensory periphery to activity in de

260 We show that the relative contributions of the two pathways to the attenuation of

261 Understanding the functional contributions of the two receptor classes may help us un

262 An important contribution of their article is that they study how nei

263 We also discuss the contribution of these changes to responses to cancer the

264 In this way, we assess the contribution of these conditions to volcanic deformation

265 ments, compromising our understanding of the contribution of these elements to important bacterial ph

266 This study evaluated the contribution of these factors to the magnitude of carbon

267 there is little to no information as to the contribution of these neurons to the generation of acute

268 that respond to S1 inputs and the magnified contribution of these neurons to the nociceptive respons

269 ers to the toxicity of anticancer drugs, the contribution of these proteins to oxaliplatin-induced pe

270 Determination of the type and relative contribution of these structural components through empi

271 MYRF, TMEM98, CRB1,VMD2/BEST1), the relative contribution of these to nanophthalmos or to less severe

272 We investigated the contributions of these cells to hepatic injury.

273 The relative contributions of these effects depend on coverage, chemi

274 enerated from lipid peroxidation damage, the contributions of these enzymes to other biological proce

275 d at physiological levels to investigate the contributions of these mechanisms to dose-dependent Hh s

276 We investigated the relative roles and contributions of these three types of interaction to sta

277 ls, to precisely characterize the respective contributions of these two lesion types to the signals t

278 sulfur-deficiency response and quantify the contributions of these two transcription factors.

279 However, the contribution of this function to tumor suppression is po

280 However, the relative contribution of this mechanism is still not fully clear

281 cture of the meningeal lymphatic system, the contribution of this network in evoking a protective ant

282 and full functionality of this synapse, the contribution of this structure as a primary driver in mo

283 ption has prevented the deconvolution of the contributions of transcription and translation to the re

284 in numerous neurodegenerative diseases, the contributions of transporter dysfunction to disease path

285 Understanding the contribution of treatment delay on progression to severe

286 ns, are providing valuable insights into the contribution of triplicated genes or groups of genes to

287 In the past, studying the contribution of tubulin and microtubules to spindle asse

288 ability in laboratory methods, with possible contribution of unmeasured population factors.

289 epithelial and immune cells, but the in vivo contributions of VacA as an important determinant of Hp

290 Here, we characterized the contribution of vacuolar polyP metabolism to K-PPn of tw

291 us experimental techniques, the atomic-level contributions of various secondary structures of lucifer

292 with CRS compared to controls, suggesting a contribution of vascular dysfunction in CRS pathophysiol

293 These results demonstrate a novel contribution of vHipp-NAcSh pathway activity to palatabi

294 have been quantified in vivo relative to the contribution of virus neutralization mediated by the Fab

295 search should elucidate further the relative contribution of vision loss and neurofibromatosis type 1

296 c male mice thus enabled us to determine the contribution of VPAC2-expressing cells (~35% of SCN cell

297 n increasing surface charge and a decreasing contribution of water molecules aligned by the surface c

298 reserved for weaker synapses, enhancing the contribution of weak synapses to somatic responses.

299 The contribution of ZIKV NS1 to placental dysfunction during

300 However, the contribution of ZO-1 to cardiac physiology remains poorl