ライフサイエンスコーパス: corepressor

1 pendently of the Groucho/Tle transcriptional corepressor.

2 (MGEs), LexA often does so in concert with a corepressor.

3 cluding Split Ends (SPEN), a transcriptional corepressor.

4 expression by functioning as a transcription corepressor.

5 sandwiched between the HDAC and its cognate corepressor.

6 cetylase 3 (HDAC3)-dependent transcriptional corepressor.

7 lling and deacetylase (NuRD) transcriptional corepressor.

8 odulated by tissue-specific coactivators and corepressors.

9 stress-inducible genes via counteraction of corepressors.

10 he glucose sensors to promote binding of the corepressors.

11 leukemia and interacts with transcriptional corepressors.

12 those that contain the Sin3 transcriptional corepressors.

13 , less is known about how CSL interacts with corepressors.

14 a counteractive regulation by the Tup-family corepressors.

15 tical role for the epigenetic repressor REST corepressor 1 (CoREST) in promoting Treg suppressive tra

16 hormone receptor (SMRT) and nuclear receptor corepressor 1 (N-CoR) that accumulated in synchronized H

17 Nuclear corepressor 1 (NCoR) associates with nuclear receptors a

18 targeted inhibition of BCL6/nuclear receptor corepressor 1 (NCoR) complex by peptidomimetic inhibitor

19 lpha) with its cosuppressor nuclear receptor corepressor 1 (NCOR).

20 Conversely, mice expressing a mutant nuclear corepressor 1 (Ncor1) allele that cannot interact with T

21 Nuclear receptor corepressor 1 (NCOR1) and NCOR2 (also known as SMRT) reg

22 Nuclear receptor corepressor 1 (NCoR1) and silencing mediator for retinoi

23 that deletion of intestinal nuclear receptor corepressor 1 (NCoR1) completely diminishes hyperbilirub

24 ng to Rev-erbalpha recruits nuclear receptor corepressor 1 (NCoR1) into an active repressor complex.

25 Nuclear receptor corepressor 1 (NCoR1) is considered to be the major core

26 stone deacetylase 3 (HDAC3)-nuclear receptor corepressor 1 (NCoR1) repressor complex.

27 Expression of a mutated nuclear corepressor 1 (NCoR1) that lacks 2 NR interacting domain

28 The nuclear receptor corepressor 1 (NCOR1) was reported to mediate the domina

29 -binding protein-binding protein and nuclear corepressor 1 (NCoR1), fundamentals for the PPARgamma-me

30 in keratinocytes for either nuclear receptor corepressor 1 (NCoR1)/silencing mediator for retinoid or

31 ice ablated selectively for nuclear receptor corepressor 1 (NCoR1)/silencing mediator for retinoid or

32 llaboration with the corepressor CoREST/REST corepressor 1 (Rcor1) and regulates cell fates by epigen

33 Moreover, METH caused interactions of REST corepressor 1 and methylated CpG binding protein 2 with

34 ediator of transcription 13/nuclear receptor corepressor 1 axis, which in turn promotes Mef2 inhibiti

35 Knockdown of nuclear receptor corepressor 1 in primary male T cells abolished the effe

36 ), TP53 (P = 0.0006), and RB Transcriptional Corepressor 1 mutations (P = 0.03).

37 ment-1 silencing transcription factor (REST) corepressor 1, methylated CpG binding protein 2, and his

38 ceptor-interacting protein, nuclear receptor corepressor 1, to specific cis-regulatory elements in th

39 ue in that interaction with nuclear receptor corepressors 1 and 2 (NCoR1/2) is required to engage its

40 action between TR-alpha and nuclear receptor corepressor 2 (NCOR2) and suppressed Pln transcription.

41 ion Factor (CoREST) and the Nuclear Receptor Corepressor 2 (NCOR2).

42 ucose homeostasis regulator nuclear receptor corepressor 2 repression, and chromatin immunoprecipitat

43 NCOR2 (nuclear receptor corepressor 2) SNP rs150954431 was associated with P=1.1

44 on through interaction with nuclear receptor corepressor 2/histone deacetylase 3 for its repression.

45 of protein domains to create a diversity of corepressors, achieving similar properties with differen

46 ins (TLE1-4) are a family of transcriptional corepressors acting downstream of multiple signalling pa

47 at Src-1(-/-) mice have RTH due to unopposed corepressor action.

48 019) describe a role for the neuronal CoREST corepressor and changes in juvenile hormone (JH) and ecd

49 CSL interacts with both transcriptional corepressor and coactivator proteins, functioning as bot

50 lar basis for the anticancer actions of this corepressor and identify NCoR as a potential molecular t

51 in directly interacts with a transcriptional corepressor and ligand of the Slug promoter, ZBRK1.

52 ubcellular localization of CAR; 4) increases corepressor and reduces coactivator interaction with the

53 the SHH pathway, through recruitment of BCOR corepressor and SIRT1 deacetylase.

54 ndicate that TTP acts as a bona fide ERalpha corepressor and suggest that this protein may be a contr

55 r WOX1/STF, the LEUNIG (LUG) transcriptional corepressor and the ANGUSTIFOLIA3 (AN3) transcriptional

56 LTM interacts with the TOPLESS corepressor and with several transcription factors that

57 has 10-fold greater potency than endogenous corepressors and binds an essential region of the BCL6 l

58 ination of the mRNA start site by Tup family corepressors and CBF/NF-Y proteins.

59 ent stem cells by recruiting transcriptional corepressors and coactivator complexes onto neuroectoder

60 scriptional repressor complexes comprised of corepressors and histone-modifying enzymes to control ge

61 oic acid and thyroid hormone receptor (SMRT) corepressors and is largely unresponsive to ligand activ

62 These transcriptional corepressors and tumor suppressors inhibit the expressio

63 NCoR1 (nuclear receptor corepressor) and SMRT (silencing mediator of retinoid an

64 omatin architecture created by the Cyc8-Tup1 corepressor, and that releasing the P nucleosome contrib

65 ooperatively recruit TOPLESS (Mt-TPL) family corepressors, and this recruitment is required for STF f

66 Notably, both NCoR and SMRT corepressors are subject to alternative mRNA splicing, y

67 eracted with histone H3-binding proteins and corepressor-associated proteins but not with H3 or the c

68 mly weakens coactivator associations but not corepressor associations, implicating partial agonism as

69 The transcriptional corepressor B-cell lymphoma 6 (BCL6) is a member of the

70 The transcriptional corepressor BASP1 interacts with WT1 and mediates WT1's

71 of-function mutations of the transcriptional corepressor BCOR are recurrent and enriched in SHH medul

72 lycomb repressive complex 1.1 (PRC1.1), BCL6 corepressor (BCOR) and KDM2B, which helps target the com

73 frameshift mutations of the BCL6 interacting corepressor (Bcor) gene, most commonly within a 9-bp "ho

74 heterozygous mutations in the X-linked BCL-6 corepressor (BCOR) gene.

75 The BCL6 Corepressor (BCOR) is a component of a variant Polycomb

76 B cell lymphoma 6 (BCL6) corepressor (BCOR) was discovered as a BCL6-interacting

77 Despite both corepressors being present in the liver, deletion of SMR

78 nd that this phosphorylation is required for corepressor binding and ultimately HXT expression.

79 type of mice engineered to express BCL6 with corepressor binding site mutations.

80 y X-ray crystallography, reveals a monomeric corepressor-bound protein.

81 ptor gamma (PPARgamma) in an inverse agonist/corepressor-bound transcriptionally repressive conformat

82 ctor binding surfaces that are folded in the corepressor-bound wild-type protein are disordered.

83 y2 dephosphorylates Mth1, an Rgt1 associated corepressor, but does not dephosphorylate Rgt1 at sites

84 (BCOR) was discovered as a BCL6-interacting corepressor, but little is known about its other biologi

85 ones associated with aberrant recruitment of corepressors by TRalpha1 mutants underlies pathological

86 tivity of the NADH-sensitive transcriptional corepressor C-terminal binding protein 1 (CtBP1).

87 ding decreased levels of the transcriptional corepressor C-terminal binding protein 1.

88 w that the expression of the transcriptional corepressor C-terminal binding protein-2 (CtBP2) is elev

89 hysical interaction with the transcriptional corepressors C-terminal binding proteins (CtBP1/2), are

90 ations in human Atrophin1, a transcriptional corepressor, cause dentatorubral-pallidoluysian atrophy,

91 d that MTA1 association with nucleosomes and corepressor/coactivator complexes is dynamic.

92 herefore, functional consequences of altered corepressor/coactivator exchange were examined at Mcsfr,

93 (PTMs) on histones and coregulators such as corepressors, coactivators, DNA-binding factors and PTM

94 However, both corepressors collaborate to control hepatic lipid conten

95 of JAZ10.4 links transcription factors to a corepressor complex and suggest how JA-induced transcrip

96 show that RUNX1 is a component of the HDAC3 corepressor complex and that HDAC3 preferentially binds

97 ons correlated with reduced occupancy of the corepressor complex at inflammatory promoters, providing

98 ensus RORE or RevDR2 motifs and overlap with corepressor complex binding.

99 tumor growth, independent of IKK2, MTA2/NuRD corepressor complex negatively regulates NF-kappaB signa

100 trans-recruitment of the GR-N-CoR/SMRT-HDAC3 corepressor complex on these enhancers.

101 protein is a component of a transcriptional corepressor complex recently linked to the silencing of

102 eport that expression of the transcriptional corepressor complex subunits GPS2 and SMRT was significa

103 of MLH1 and other CIMP genes, and recruits a corepressor complex that includes its heterodimeric part

104 Promoter-bound ZNF304 recruits a corepressor complex that includes the DNA methyltransfer

105 ntify NCoR1-GPS2-HDAC3 as a NELF-interacting corepressor complex that is associated with repressed HI

106 s partner LSD1, and ZMYM2 recruits LSD1/HDAC corepressor complex to MERVL LTR for transcriptional rep

107 ZTF-11 functions together with the MuvB corepressor complex to suppress the activation of non-ne

108 lass IIa deacetylase that interacts with the corepressor complex together with the highly active clas

109 in 1), identified as a component of the CtBP corepressor complex, binds to nearby DNA elements to ass

110 P is not only able to interact with the NCoR corepressor complex, but also with the H3K4 methyltransf

111 ion of GPS2 and TBL1, components of the SMRT corepressor complex, but not histone deacetylase 3 (HDAC

112 First identified as part of the NCoR-SMRT corepressor complex, GPS2 is known to play an important

113 nt of the mammalian Sin3-histone deacetylase corepressor complex, severely impairs the competitive re

114 chromatin binding module in the HDAC1:MIDEAS corepressor complex.

115 f retinoic acid and thyroid receptors (SMRT) corepressor complex.

116 t has been thought that HDACs associate with corepressor complexes and repress gene transcription; ho

117 lation by histone deacetylase (HDAC)-bearing corepressor complexes is poorly understood.

118 AC3) is the catalytic component of NCoR/SMRT corepressor complexes that mediate the actions of transc

119 AC1/2) form the core catalytic components of corepressor complexes that modulate gene expression.

120 hly phosphorylated HDAC2 is recruited within corepressor complexes to regulatory regions, while the n

121 is associated with multiple transcriptional corepressor complexes, including CtBP/LSD1/HDAC complexe

122 These results suggest that corepressor complexes, including HDAC1 or HDAC2 homodime

123 ended on class I HDACs and involved multiple corepressor complexes, including HDAC1/2-containing Sin3

124 and transcriptional activity by inactivating corepressor complexes, which associate in a ligand-depen

125 and is mediated by multiple HDAC1-containing corepressor complexes.

126 n, BCL11A was found to interact with several corepressor complexes; however, the mechanisms underlyin

127 The Tup family corepressors contribute to critical cellular responses,

128 TFs (n = 2662), coactivators (COA; n = 766); corepressors (COR; n = 599); mixed function coregulators

129 production in macrophages by recruiting the corepressor CoREST to the Th promoter.

130 CtBP's association with the transcriptional corepressor CoREST, and was critical for CtBP2 induction

131 4 (H3K4) residues in collaboration with the corepressor CoREST/REST corepressor 1 (Rcor1) and regula

132 s target genes depends on its recruitment of corepressors (CtBP, BRG1) or coactivators (p300) althoug

133 via a cascade involving the transcriptional corepressor Ctbp2 and the Notch suppressor Sirt1.

134 A is downregulated by a pathway in which the corepressor DACH1 represses ATF6, which is an inducer of

135 cides with the predicted binding site of the corepressor DAX-1 (dosage-sensitive sex reversal, adrena

136 In contrast, ligand-induced corepressor-dependent NR repression appears to occur thr

137 factor that plays the role of coactivator or corepressor, depending on the cell and promoter contexts

138 is carried out by histone deacetylase (HDAC)/corepressor element-1 silencing transcription factor (Co

139 hip with a host kinase and a transcriptional corepressor enables retrograde regulation by vPK of ZEBR

140 expression by interacting with transcription corepressor/enhancer complexes and they orchestrate down

141 epresentative targets of the transcriptional corepressor ETO2.

142 with reduced protein level of hematopoietic corepressor ETO2.

143 The Sds3 transcriptional corepressor facilitates the assembly of the 1- to 2-MDa

144 h the Dnmt1, Sin3A, Nurd, CoRest, and B-Wich corepressor families.

145 Our findings show that the TPL/TPR corepressor family are components of the central circadi

146 We discover the neuronal corepressor for element-1-silencing transcription factor

147 ranscription factor Eos (Ikzf4), an obligate corepressor for Foxp3.

148 DNA damage response, acting as an essential corepressor for KRAB family zinc finger proteins (KRAB-Z

149 uN promoter as an antirepressor of Fur and a corepressor for NsrR.

150 ings, C-DIM12 also stabilized binding of the Corepressor for Repressor Element 1 Silencing Transcript

151 Thus, RUNX1 and PU.1 cooperate to exchange corepressors for coactivators, and the specific corepres

152 Here we report that CRY1/2 serve as corepressors for many NRs, indicating a new facet of cir

153 functional departure from the canonical MEF2 corepressor function of class IIa HDACs.

154 ian BEN-solo factor that conserves the Notch corepressor function of Insv but not its capacity to bin

155 lar domain structure and performs a parallel corepressor function, revealed that the plant TPLs have

156 derstanding of gene-specific coactivator and corepressor functions across the AML1-ETO/RUNX1 cistrome

157 utations in the PRC1-like component and BCL6-corepressor gene Bcor.

158 We show that the corepressor Grg3 is expressed in almost all beta-cells t

159 anscriptional coregulators (coactivators and corepressors) have emerged as the principal modulators o

160 note, both the transcription factor Sp1 and corepressor HDAC1 associated with the +38/+187 region wh

161 The nuclear localization of the MEF2 corepressor HDAC4 is impaired by Mrf4 knockdown, suggest

162 -alpha) and histone deacetylase 2 (HDAC2), a corepressor important for glucocorticoid action and whos

163 as a coregulator of AR with properties of a corepressor in a context-dependent manner.

164 20 (H4K20me1), is a context-dependent GATA-1 corepressor in erythroid cells.

165 n that functions as a master transcriptional corepressor in hematopoiesis.

166 GR-interacting protein-1 (GRIP1) is a GR corepressor in macrophages, however, whether GRIP1 media

167 gene-related 1 (MTGR1) is a transcriptional corepressor in the myeloid translocation gene/Eight-Twen

168 dole-3-acetic acid (Aux/IAA) transcriptional corepressors in controlling response dynamics and highli

169 at p300/CBP and HDACs act as coactivators or corepressors in histone acetylation-induced PKCdelta up-

170 ts define a novel function of Groucho family corepressors in peripheral T cells and demonstrate that

171 retinoid or thyroid-hormone receptors (SMRT) corepressors in skin keratinocytes, Dex-induced direct r

172 binding of enhancer-associated coactivators/corepressors, including p300 and RIP140, permitting full

173 main 1 (AD1) of E2A has specifically reduced corepressor interaction due to E2A-specific amino acid c

174 On the other hand, the weak E2A-AD1-corepressor interaction imposes a critical importance on

175 LXR inverse agonist SR9243 that induces LXR-corepressor interaction.

176 ence for the differential involvement of E2A-corepressor interactions in distinct leukemogenic pathwa

177 Blocking SALL4-corepressor interactions released suppression of PTEN (t

178 The 2525 amino acid SMRT corepressor is an intrinsically disordered hub protein r

179 as Arabidopsis thaliana, the most prominent corepressor is TOPLESS (TPL), which plays a key role in

180 -CoREST (lysine-specific demethylase 1; REST corepressor) is an ideal model system to study the inter

181 our findings suggest that YY1, with HDACs as corepressors, is a critical negative transcriptional reg

182 HDAC3 acts canonically as a transcriptional corepressor, it functions as a coactivator of oestrogen-

183 ing the synergy between NF-kappaBeta and the corepressor JDP2.

184 TAT3 suppresses the cellular transcriptional corepressor Kruppel-associated box domain-associated pro

185 higher affinity for BCL6 than its endogenous corepressor ligands to evaluate their therapeutic effica

186 e we indicate a role for the transcriptional corepressor Lysine-Specific Demethylase 1 (LSD1) and its

187 wnstream ETO-interacting sequence (DES), for corepressor-mediated repression.

188 ption factors together with coactivators and corepressors modulate the expression of genes that regul

189 A where AR interaction with coactivators and corepressors modulates transcription.

190 Ralpha, but decreased the association of its corepressors (N-CoR and SMRT), with the miR-122 DR1 and

191 shing interactions with the nuclear receptor corepressor (NCOR or SMRT) render HDAC3 nonfunctional in

192 2 (GPS2), a subunit of the nuclear receptor corepressor (NCOR) and histone deacetylase 3 (HDAC3) com

193 of the receptor along with nuclear receptor corepressor (NCoR) and silencing mediator of retinoic ac

194 f the MeCP2 with DNA or the nuclear receptor corepressor (NCoR)/silencing mediator of retinoic acid a

195 We show that the nuclear receptor corepressor NCoR1 is a key target of proteolysis and phy

196 on of the tumor-suppressive nuclear receptor corepressor NCOR1.

197 ct repression, but not bindings of GR and of corepressors NCoR1/SMRT, was abolished, indicating that

198 Recently, the nuclear corepressor, NCOR1, has been postulated to regulate TSH

199 e model harboring a mutated nuclear receptor corepressor (NCOR1DeltaID) (Thra1(PV/+)Ncor1(DeltaID/Del

200 Nuclear receptor corepressors (NCORs) are transcription co-regulators phy

201 f a functional complex with nuclear receptor corepressors (NCORs) were critical in restricting differ

202 pha1 mutants to properly release the nuclear corepressors (NCORs), thereby inhibiting thyroid hormone

203 mer partner) is a well-known transcriptional corepressor of bile acid and lipid metabolism in the liv

204 studies identify PIAS3 as a transcriptional corepressor of EKLF for at least a subset of its target

205 ual conundrum: mechanistically, as the FOXO1 corepressor of glucokinase is unknown, and clinically, a

206 rt that SIN3A is the insulin-sensitive FOXO1 corepressor of glucokinase.

207 h GR in protein complexes and functions as a corepressor of GR-mediated transcription.

208 tion of human small heterodimer partner, the corepressor of hCYP7A1 transcription, was also confirmed

209 oform of BET family member BRD4 (BRD4S) as a corepressor of HIV-1 transcription.

210 WASp from a transcriptional coactivator to a corepressor of nuclear factor (NF)-kappaB response genes

211 modeling and histone deacetylase (NuRD), and corepressor of RE1 silencing transcription factor (CoRES

212 Here we have discovered that MTA1 is a novel corepressor of serum and glucocorticoid-inducible kinase

213 We identified ZMYND8 as a transcriptional corepressor of the H3K4 demethylase JARID1D.

214 ein (SMILE) has been identified as a nuclear corepressor of the nuclear receptor (NRs) family.

215 Corepressors of the Polycomb family, which are frequentl

216 romatin-modifying proteins Sin3a and coREST (corepressors of the transcription factor REST) and subse

217 -modifying proteins (CMPs) Sin3a and coREST (corepressors of the transcription factor REST).

218 eacetylase (HDAC) classes I and II served as corepressors of YY1, and, accordingly, HDAC inhibitors i

219 retinoid or thyroid-hormone receptors (SMRT) corepressors or histone deacetylase 3 (HDAC3), Dex-induc

220 coactivator peptide, and reduce binding of a corepressor peptide to RORgamma LBD.

221 ed when either CRY is bound to the circadian corepressor PERIOD2.

222 BBX25 and BBX24 function as transcriptional corepressors, probably by forming inactive heterodimers

223 on, and what dictates its coactivator versus corepressor properties is unknown.

224 s GRIP1 coactivator but, remarkably, not its corepressor properties.

225 emonstrated that engineered BCL6 interacting corepressor protein (Bcor) mutation in hematopoietic ste

226 ins histone deacetylases 1 and 2, the MIDEAS corepressor protein and a protein called DNTTIP1 whose f

227 through the recruitment of nuclear receptor corepressor protein and silencing mediator of retinoid a

228 methylase-1 (LSD1/KDM1A) in complex with its corepressor protein CoREST is a promising target for epi

229 HP1) isoforms and the generic HP1-associated corepressor protein KAP1 all resulted in growth inhibiti

230 ng a MYC mutant unable to associate with the corepressor protein MIZ1 (ZBTB17).

231 H3K4 in peptide substrates, but requires the corepressor protein, CoREST, to demethylate nucleosome s

232 i, where it mono-ADP ribosylates the nuclear corepressor protein, KAP1, and facilitates KAP1 interact

233 , HDAC2, and HDAC3) are recruited by cognate corepressor proteins into specific transcriptional repre

234 unction of AF2 is to recruit coactivator and corepressor proteins that allow ERalpha to oscillate bet

235 th CSL is thought to both disrupt binding of corepressor proteins to CSL and anchor NICD to CSL, prom

236 ession in glial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to in

237 tion of the maize (Zea mays) transcriptional corepressor RAMOSA1 ENHANCER LOCUS2 (REL2), a unique mem

238 The corepressor Rcor1 has been linked biochemically to hemat

239 epressors for coactivators, and the specific corepressors recruited to PU.1 as a consequence of RUNX1

240 We found that corepressor recruitment by RUNX1 contributes to a block

241 ts were shown to play a role in differential corepressor recruitment.

242 lterations in the balance of coactivator and corepressor recruitment.

243 e retinoblastoma (RB) family transcriptional corepressors regulate diverse cellular events including

244 R1 can interact with GFI1, a transcriptional corepressor required for Paneth cell differentiation, an

245 Here, we show AR and its corepressor, REST, function as transcriptional-repressor

246 also defines the mechanism of action of the corepressor-selective inverse agonist T0070907, and reve

247 The corepressor SIN3 controls histone acetylation through as

248 Taken together, these data demonstrate that corepressor specificity exists in vivo and that NCoR1 is

249 adipogenesis is associated with a switch in corepressor splicing from NCoRomega to NCoRdelta, which

250 ompetitively displacing RUNX1 and recruiting corepressors such as histone deacetylase 3 (HDAC3).

251 lso associated with extensive recruitment of corepressors such as NCoR and HDACs, indicating that thi

252 wild-type E2A is silenced by high levels of corepressors, such as the AML1-ETO fusion protein in t(8

253 Tup11/12 (the Tup-family corepressors) suppress direct binding of Rst2 to UAS2, b

254 Coactivators and corepressors tethered by proteins similar to ASEs and XS

255 SIN3 is a transcriptional corepressor that acts as a scaffold for a histone deacet

256 has been characterized as a transcriptional corepressor that can associate with many different trans

257 D complex is a multi-protein transcriptional corepressor that couples histone deacetylase and ATP-dep

258 findings show that Mth1 is a transcriptional corepressor that facilitates the recruitment of Ssn6-Tup

259 HDAC4 is a transcriptional corepressor that has been linked to synaptic plasticity

260 1 (transducin-like enhancer of split 1) is a corepressor that interacts with a variety of DNA-binding

261 d CLOCK-BMAL1, thereby reconstituting a NuRD corepressor that is important for circadian transcriptio

262 ssor 1 (NCoR1) is considered to be the major corepressor that mediates ligand-independent actions of

263 ene family member MTG16 is a transcriptional corepressor that relies on the DNA-binding ability of ot

264 signal from the sensors to the Mth1 and Std1 corepressors that are required for repression of HXT gen

265 PXR associates with multiple corepressors that attenuate and coactivators that enhanc

266 Promoter-bound MAFG recruits a set of corepressors that includes its heterodimeric partner BTB

267 pression involves a class of proteins called corepressors that link transcription factors to chromati

268 sors associate with ARF proteins and recruit corepressors that prevent auxin-induced gene expression.

269 te myelogenous leukemia, are transcriptional corepressors that regulate hematopoietic stem cell progr

270 verlap specific interaction sites for alpha2 corepressors: the Mcm1 interaction site in the central a

271 r-associated proteins but not with H3 or the corepressors themselves.

272 , dTcf/Pan partners with the transcriptional corepressor TLE/Groucho (Gro) and inhibits gene expressi

273 lis gastrulae and find that occupancy of the corepressor, TLE/Groucho, is a better indicator of tissu

274 The corepressor Tle3 was also identified in the screen and w

275 and establish that NCOA5 functions as an LXR corepressor to attenuate Abca1 expression.

276 HDACs 1 and 2 are recruited by the MTA1 corepressor to form the catalytic core of the complex.

277 ur data suggest that, rather than recruiting corepressors to enhancers, Scl prevents ectopic cardioge

278 mutated Bcl6 encoding Bcl-6 that cannot bind corepressors to its BTB domain resulted in disruption of

279 vation domain, and likely the recruitment of corepressors to the Foxo1 locus by c-Myb.

280 gether support a model in which STF recruits corepressors to transcriptionally repress its targets du

281 uiting the Groucho/TUP1-like transcriptional corepressor TOPLESS (TPL).

282 This NINJA-like recruits the corepressor TOPLESS that contributes to the suppressive

283 KIX9, which act as adaptor proteins for the corepressor TOPLESS.

284 ession and for physical interaction with the corepressor TOPLESS.

285 Here we report that the transcriptional corepressor TRIM28 is the major binding partner for nucl

286 SETDB1 is required, but the widely utilized corepressor TRIM28/Kap1 is not.

287 Here we show that the corepressor Tup1 is sumoylated, at two specific lysines,

288 saccharomyces pombe fission yeast Tup family corepressors Tup11 and Tup12 (Tup11/12), which are ortho

289 ind to the Groucho-Tup1 type transcriptional corepressors Tup11 and Tup12, and locally antagonize the

290 mRNA splicing, yielding a series of distinct corepressor variants with highly divergent functions.

291 e data suggest that MTGR1, a transcriptional corepressor well characterized in hematopoiesis, plays a

292 trated that PER2 served as a transcriptional corepressor, which recruited polycomb proteins EZH2 and

293 on repressor through recruitment of Atrophin corepressors, which bind to TLX via a conserved peptide

294 n of Tle4, a member of the Groucho family of corepressors, which is then recruited to a distal regula

295 e state recruits peptides from two different corepressors, while another recruits just one, providing

296 sferase repressor (NIR) is a transcriptional corepressor with inhibitor of histone acetyltransferase

297 nding protein-1 (CtBP1) is a transcriptional corepressor with multiple in vitro targets, but its in v

298 with one of its targets, the transcriptional corepressor, XCtBP.

299 ions is demonstrated for the transcriptional corepressor ZMYM2/ZNF198 where its multi-SUMO-binding ac

300 ption machinery, and 'ejects' the elongation corepressor ZMYND11(8,9).