ライフサイエンスコーパス: cortical bone

1 or), and bone type (alveolar bone proper vs. cortical bone).

2 r in vivo imaging of bound and pore water in cortical bone.

3 ation artifacts in the lungs, and imaging of cortical bone.

4 in extraction sockets with an intact crestal cortical bone.

5 PET data, because of their ability to image cortical bone.

6 pha(-/-) mice of both genders had unaffected cortical bone.

7 ed, albeit regionally-dependent, benefits to cortical bone.

8 ptosis-focused RT-PCR gene pathways in mouse cortical bone.

9 lar bone network that replaces the amputated cortical bone.

10 lar, they significantly differ from those of cortical bone.

11 d bone mineral density in the trabecular and cortical bone.

12 uctural changes of an intact piece of bovine cortical bone.

13 function RA patients with thinned metacarpal cortical bone.

14 markedly reduced on the endosteal surface of cortical bone.

15 ty, area and strength of both cancellous and cortical bone.

16 scraping device was used to obtain strips of cortical bone.

17 sa, with no allowance for particle escape to cortical bone.

18 ost combinations of source-target regions in cortical bone.

19 hanced bone induction, area of new bone, and cortical bone.

20 d highly in osteocytes within trabecular and cortical bone.

21 carried through the haversian canals within cortical bone.

22 r 6 source-target tissue combinations within cortical bone.

23 ar and palatal tori as sources of autogenous cortical bone.

24 stmenopausal women; the largest effect is on cortical bone.

25 f therapy if the osteomyelitis is limited to cortical bone.

26 reatment may impair toughening mechanisms in cortical bone.

27 th of the HC material to approaching that of cortical bone.

28 oxyapatite-like mineral matrix that makes up cortical bone.

29 ated in notched and unnotched beams of sheep cortical bone (2x2x20 mm), with monotonic and fatigue lo

30 vented the development of trabecular but not cortical bone abnormalities.

31 s signaling pathway was required for optimal cortical bone accrual at the periosteum in mice.

32 Spaceflight resulted in lower cortical bone accrual in the femur but had no effect on

33 Biopsies of proximal femoral cortical bone adjacent to the fracture site were obtaine

34 unknown MR low-intensity class encompassing cortical bones, air cavities, and metal artifacts.

35 Probing and palpation of the hard cortical bone, also known as the "ventral lamina", cover

36 veals that the chemical shift frequencies of cortical bone and 10% carbonated apatite are similar but

37 Using Slc30a10 (-/-) mice, a loss of cortical bone and a marked decrease in S100g and Trpv6 i

38 e (UTE) sequences have been used to separate cortical bone and air, and the Dixon technique has enabl

39 g to characterize deficits in trabecular and cortical bone and have evaluated the 'functional muscle-

40 he long bones of mutant mice contain thinner cortical bone and reduced trabecular bone volume.

41 Descriptive bone analysis revealed thin cortical bone and sparse cancellous bone patterns.

42 gher bone area-to-total area ratios, thicker cortical bone and trabecular bone, significantly higher

43 s protection occurred in cancellous, but not cortical, bone and was associated with a failure to incr

44 se was caused by a deficiency of sFRP4, that cortical-bone and trabecular-bone homeostasis were gover

45 were taken at the 4% (trabecular bone), 20% (cortical bone), and 66% (for measurement of MCSA) sites

46 d polycarbonate to simulate trabecular bone, cortical bone, and cartilage.

47 by wide metaphyses, significant thinning of cortical bone, and fragility fractures.

48 ed reduced trabecular bone volume, decreased cortical bone, and increased osteoclast number in bone e

49 stence of S. aureus in submicron channels of cortical bone, and the diagnostic role of polymorphonucl

50 s, the rate of bone formation was reduced in cortical bone, and the parietal bones were 45% thinner t

51 gulator of bone mass with high expression in cortical bone, and Wnt16(-/-) mice have reduced cortical

52 Trabecular bone, as compared with cortical bone, appeared highly heterogeneous on the scat

53 used this technique to study trabecular and cortical bone architecture.

54 (43)Ca NMR spectra of bovine cortical bone are analyzed by comparing to the natural-a

55 on (ICRP)-recommended absorbed fractions for cortical bone are given only for the CBE as target regio

56 cts of parathyroid hormone on trabecular and cortical bone are primarily mediated via G(s)alpha in os

57 oup had lower bone measures at the 20% site (cortical bone area and cortical BMC at the tibia, total

58 moral bone volume, trabecular thickness, and cortical bone area and thickness were significantly incr

59 ercentage BF was inversely related to radial cortical bone area, total bone cross-sectional area (CSA

60 varying thicknesses (0.5 to 4 mm) of buccal cortical bone around the implants.

61 mounts of trabecular bone and unusually thin cortical bone, as a result of differential regulation of

62 Folfiri nor ACVR2B/Fc had effects on femoral cortical bone, as shown by unchanged cortical bone volum

63 leads to geometric and structural changes in cortical bone, as well as asymmetry in fracture healing.

64 -XRF allowed resolving thin Gd structures in cortical bone, as well as correlating them with calcium

65 situ beneath the periosteal surface of mouse cortical bone at depths up to 50 microm with laser scann

66 ted mice) and in the width and volume of the cortical bone at the femoral diaphysis (+24% and +20%, r

67 ted bone was equivalent to that of untreated cortical bone at week 4, while the bone hardness around

68 ree-dimensional electron transport model for cortical bone based on Monte Carlo transport and on bone

69 Porcine cortical bone blocks were subjected to defatting, differ

70 histomorphometrically for area of new bone, cortical bone, bone marrow, and residual DFDBA.

71 f mineralization are modified in the brittle cortical bone but a cluster of autophagy-associated gene

72 d growth and improved mineralization and the cortical bone, but it failed in normalizing growth plate

73 osteocytes is critical for full anabolism in cortical bone, but tempers bone gain in cancellous bone.

74 PTH increased the HyA content of cortical bone by 2-fold while not affecting the HyA cont

75 t 3.0 T and was validated in sheep and human cortical bone by using exchange of native water with deu

76 While canals in cortical bone can readily be identified and characterise

77 ated Wnt16 expression in both trabecular and cortical bone compared with wild type (WT) mice.

78 of estrogens on the cancellous, but not the cortical, bone compartment that represents 80% of the en

79 ity was increased in both the trabecular and cortical bone compartments in nestin-ERalpha(-/-) mice c

80 reover, the buccal and mesial regions of the cortical bone concentrated significantly higher stress (

81 Human cortical bone contains two types of tissue: osteonal and

82 btraction mask to eliminate high-attenuation cortical bone contours.

83 As the elastic mechanical properties of cortical bone correlated with porosity, we would recomme

84 with antibodies to sclerostin corrected the cortical-bone defect.

85 been confirmed as representing osteitis and cortical bone defects, respectively, adding to what was

86 n myeloid progenitors accelerates healing of cortical bone defects.

87 Muscle attenuation as well as trabecular and cortical bone densities revealed negative correlations w

88 We measured trabecular bone densities, cortical bone densities, VAT areas, and subcutaneous adi

89 implicate Aldh1a1 as a novel determinant of cortical bone density and marrow adiposity in the skelet

90 ious reports that deficits in trabecular and cortical bone density and structure independently contri

91 (HR-pQCT), we demonstrate low trabecular and cortical bone density contributing to lower volumetric b

92 y with estrogen has been reported to improve cortical bone density in postmenopausal women with asymp

93 r number and increased separation; the lower cortical bone density results from thinner cortices, whe

94 Cyclical growth marks in cortical bone, deposited before attainment of adult body

95 Cortical bone-derived stem cells (CBSCs) and cardiac-der

96 tly reduced both reactive bone formation and cortical bone destruction by CM from LAC cultures.

97 was conducted to identify the role of Scx in cortical bone development and fracture healing.

98 decreased bone resorption and an increase in cortical bone due to increased bone formation.

99 atient--eg, the knee), beam hardening (about cortical bone--eg, the femoral shaft), and cone-beam art

100 t regions: the cortical haversian space, the cortical bone endosteum (CBE) and the cortical bone volu

101 metric placement of trabecular bone within a cortical bone envelope represents yet another mechanism

102 d contrast enhancement decrease, but fat and cortical bone-equivalent signal intensity increases.

103 F-alpha-dependent systemic inflammation, and cortical bone erosion.

104 The structure of human cortical bone evolves over multiple length scales from i

105 he radius, a skeletal site that is primarily cortical bone, exist and also differ by sex.

106 ls showed positive outcome on trabecular and cortical bone formation in extraction sockets with an in

107 ineralization rate and higher trabecular and cortical bone formation rate was displayed in CCR3-defic

108 th either maintained (trabecular) or higher (cortical) bone formation as compared to vehicle-treated

109 Cortical-bone fragility is a common feature in osteoporo

110 ortical bone free water T1 (R(2) = 0.72) and cortical bone free water concentration (R(2) = 0.62) sho

111 Conclusion The cortical bone free water concentration and free water T1

112 Cortical bone free water T1 (R(2) = 0.72) and cortical b

113 ficiency promoted progressive cancellous and cortical bone gain in both mutants, although more pronou

114 lone had greatly reduced trabecular density, cortical bone geometry properties, and bone mineral cont

115 Substantial deficits in trabecular vBMD, cortical bone geometry, and muscle were observed at CD d

116 size, muscle mass, trabecular bone density, cortical bone geometry, and strength.

117 ing was that surgery markedly changed tibial cortical bone geometry.

118 with hyaluronic acid (HY) and cancellous and cortical bone granules from the same donor: DBM alone (1

119 oss on the material properties of mandibular cortical bone have received little study.

120 and differentially regulates trabecular and cortical bone homeostasis.

121 Regulation of cortical-bone homeostasis has proved elusive.

122 terized by radiolucent lesions affecting the cortical bone immediately under the periosteum of the ti

123 ation and that it is associated with thinner cortical bone in adult male mice.

124 ble for trabecular bone in male mice and for cortical bone in both genders.

125 r the trabecular bone in female mice and the cortical bone in both genders.

126 ant for trabecular bone in male mice and for cortical bone in both males and females.

127 s, and there was complete destruction of the cortical bone in much of the proximal tibias by 4 weeks.

128 d (ii) an osteoporosis mouse model comparing cortical bone in sham-treated and ovariectomized mice.

129 e PET/CT, PET/MR ignores the contribution of cortical bone in the attenuation map.

130 in the cortical vertebrae in one strain) and cortical bone in the calvariae (bone mineral density was

131 Trabecular and cortical bone in the distal metaphysis was made osteopor

132 Mandibular cortical bone in the edentulous mandibles differed from

133 ne accrual in the femur but had no effect on cortical bone in the humerus or calvarium.

134 he trabecular bone in the first 6 months and cortical bone in the subsequent 6 months.

135 longitudinal relaxation time [T1]) of human cortical bone in vivo.

136 ion in osteoblasts and osteocytes lining the cortical bone, in chondrocytes and in the sinus lining c

137 Implants placed in sites with thin cortical bone increased the chance for a patient to lose

138 ory cytokines, through small perforations of cortical bone, increases the rate of bone remodeling and

139 It was found that fracture in human cortical bone is consistent with strain-controlled failu

140 s show that the true transverse toughness of cortical bone is far higher than previously reported.

141 ilar but the quadrupole coupling constant of cortical bone is larger than that measured for model com

142 rom the phase information of the first echo; cortical bone is segmented using a dual-echo technique.

143 n in periosteal bone callus formation at the cortical bone junction as determined by MicroCT and hist

144 homozygous for the ALAD-1 allele have higher cortical bone lead levels; this implies that they may ha

145 esembles characteristics of younger, healthy cortical bone, leads to improved bone quality.

146 Occasionally, unusual apposition of cortical-bone-like layers in bone marrow space was obser

147 age analysis algorithm were used to quantify cortical bone loss and periosteal new bone formation for

148 eeve gastrectomy (VSG) caused trabecular and cortical bone loss that was independent of sex, body wei

149 of endogenous WNT16 results specifically in cortical bone loss, whereas overexpression of WNT16 surp

150 ets, while CD4+ T cells additionally induced cortical bone loss.

151 eak bone mass and age-related trabecular and cortical bone loss.

152 rs who continued throwing during aging, some cortical bone mass and more strength benefits of the phy

153 We observed significant increases in cortical bone mass and strength, notably in cortical tis

154 Estradiol increased the trabecular and cortical bone mass as well as the uterine weight, wherea

155 -/-) ) female mice had higher trabecular and cortical bone mass compared to age and sex-matched contr

156 reases at the time of a transient deficit in cortical bone mass due to the increased calcium demand d

157 a dramatic reduction of both trabecular and cortical bone mass in homozygous mutants.

158 eased bone formation and thus cancellous and cortical bone mass in skeletally mature rodents.

159 with estradiol increased the trabecular and cortical bone mass to a similar extent in both Wnt16(-/-

160 Once throwing activities ceased, the cortical bone mass, area, and thickness benefits of phys

161 terine weight, whereas no effect was seen on cortical bone mass, fat mass, or thymus weight.

162 etons as evidenced by reduced trabecular and cortical bone mass, lower bone mineral density, and a sl

163 eage show significantly lower trabecular and cortical bone mass, serum and bone marrow PDGF-BB concen

164 ontributes to bone repair and maintenance of cortical bone mass.

165 r osteocytes did not influence cancellous or cortical bone mass.

166 ice) yielded markedly reduced trabecular and cortical bone mass.

167 tical bone, and Wnt16(-/-) mice have reduced cortical bone mass.

168 However, scaffolds possess both cortical bone-matching mechanical properties and excelle

169 Both trabecular and cortical bone measurements by micro-CT did not reveal an

170 he first study to explore the role of Scx in cortical bone mechanics and fracture healing.

171 for bone mineral density and trabecular and cortical bone microarchitecture.

172 area, total bone cross-sectional area (CSA), cortical bone mineral content (BMC), periosteal circumfe

173 structure and increased both trabecular and cortical bone mineral densities in a dose-related fashio

174 Trabecular and cortical bone mineral density (BMD) and content were ass

175 t of renal transplantation on trabecular and cortical bone mineral density (BMD) and cortical structu

176 hin close proximity of the joints as well as cortical bone mineral density and periosteal new bone fo

177 al density, whereas ST-SPI diet only reduced cortical bone mineral density loss 3 wk post-OVX.

178 Cortical bone mineral density was significantly higher i

179 tions in cortical porosity and increments in cortical bone mineral density with OPG in PPR*Tg mice we

180 iminished the loss of total, trabecular, and cortical bone mineral density, whereas ST-SPI diet only

181 were internally coated with pulverized human cortical bone mixed with epoxy glue to simulate minimal

182 f blood vessel structures recovered from the cortical bone of a Tyrannosaurus rex (USNM 555000 [forme

183 ough estimate yields an OH- content of human cortical bone of about 20% of the amount expected in sto

184 ulated in osteoblast-like cells derived from cortical bone of female Prkca(-/-) mice compared with WT

185 Cortical bone of Gnas(+/p-) mice showed elevated express

186 While the increase in Rankl/Opg in cortical bone of mice lacking Sfrp4 suggests an osteobla

187 icient women, particularly on the hip and on cortical bone of the total body, are unknown.

188 R(+) perisinusoidal BMSCs differentiate into cortical bone osteoblasts solely during regeneration.

189 n) mutant mice exhibit severe cancellous and cortical bone osteopenia due to increased bone resorptio

190 , Notch2(Q2319X) mice exhibit cancellous and cortical bone osteopenia, enhanced osteoclastogenesis, a

191 1 month of age they exhibited cancellous and cortical bone osteopenia.

192 gnificantly lower yttrium uptake in bone and cortical bone over a 10-d period when DOTA was used as t

193 e in bone mineral density and trabecular and cortical bone parameters.

194 trabecular micro-architecture and preserved cortical bone parameters.

195 ro-architecture, with trends towards thicker cortical bone plate, higher trabecular connectivity dens

196 , MGUS patients have significantly increased cortical bone porosity and reduced bone strength relativ

197 etermined significance (MGUS) have increased cortical bone porosity and reduced bone strength,1 condi

198 A marker of cortical bone porosity called porosity index was defined

199 A two-point MR imaging method to assess cortical bone porosity in humans was conceived and valid

200 ging-derived SR may serve as a biomarker for cortical bone porosity that is potentially superior to B

201 ential for clinical use to assess changes in cortical bone porosity that result from disease or in re

202 nsity characterized by severe trabecular and cortical bone porosity, marked thinning of the parietal

203 r (CKD-MBD), specifically the development of cortical bone porosity.

204 given the plasticity of mammalian diaphyseal cortical bone, provides insights into the habitual level

205 eletion of Gnas (Gnas(+/p-)) have defects in cortical bone quality and strength during early developm

206 eatures include osteomalacia, thinned/porous cortical bone, reduced processing of procollagen and den

207 n these cells indeed causes insufficiency in cortical bone regeneration.

208 reased approximately 50% at the distal femur cortical bone region but not at trabecular bone region a

209 of apoptotic osteocytes was increased at the cortical bone region by approximately 40% initially obse

210 bone microstructural information for several cortical bone regions.

211 While the essential role of periosteum in cortical bone repair and regeneration is well establishe

212 This was probably due to decreased cortical bone resorption, because osteoclasts were marke

213 both marrow and endosteum in trabecular and cortical bone, respectively.

214 ed by micro-CT, correlated with femoral neck cortical bone's elastic modulus and ultimate compressive

215 Porosity index of midtibia cortical bone samples obtained from 16 donors was compar

216 In this work, cortical bone samples obtained from fibulae of 13 juveni

217 sure or predict the mechanical properties of cortical bone samples obtained from the femoral neck of

218 R experiments on bone, using powdered bovine cortical bone samples.

219 ressures between occluding teeth that exceed cortical bone shear strength, thereby permitting access

220 e sites when maintaining excess body weight, cortical bone showed a trend in the opposite direction.

221 crocomputed tomography (microCT) analysis of cortical bone showed that hPTH-infusion induced signific

222 3, 44%; grade 4, 4%), (b) increasing fat and cortical bone signal intensity at T1-weighted imaging (g

223 ons of energy were tabulated for three adult cortical bone sites considering three source and target

224 had decreased tibia trabecular bone density, cortical bone size and strength, and muscle mass.

225 Cortical bone size, trabecular bone volume, bone mineral

226 ring the diffusion fluxes of tissue water in cortical bone specimens from the midshaft of rabbit tibi

227 micro-CT-derived porosity in 13 donor human cortical bone specimens.

228 RATIONALE: Cortical bone stem cells (CBSCs) have been shown to redu

229 We showed that mesenchymal stromal cells, cortical bone stem cells, and tail-tip fibroblasts fuse

230 -destructive metrics to measure femoral neck cortical bone stiffness at the millimetre length scale.

231 d predictors of age-related deterioration of cortical bone structure and are potentially superior to

232 eletion partially prevented aging effects on cortical bone structure and mechanical properties.

233 Furthermore, EGCG resulted in reduced cortical bone structure and strength in Ts65Dn mice.

234 The changes demonstrated in the cortical bone structure, rigidity, stiffness, and modulu

235 w predictor for age-related deterioration of cortical bone structure.

236 ensitometry, preferably at a site containing cortical bone, such as the hip or forearm.

237 astic cells, and decreased smoothness of the cortical bone surface were evident within several days o

238 t crack-growth resistance behaviour of human cortical bone that accurately assesses its toughness at

239 The cortical bone that forms the structure of the cochlea, p

240 , we describe the mechanical architecture of cortical bone, the growth plate, metaphysis, and marrow

241 In cortical bone, the scattering signal was significantly h

242 In the rat tibia cortical bone, the scattering signals from two orthogona

243 bone crest; 2) tooth torque (TT); 3) labial cortical bone thickness (BT) for alveolar and basal bone

244 analyses revealed a significant reduction in cortical bone thickness and an increase in trabecular th

245 Histomorphometry confirmed increased cortical bone thickness and demonstrated significantly h

246 The WNT16 locus is a major determinant of cortical bone thickness and nonvertebral fracture risk i

247 Finally, cortical bone thickness and trabecular volume, as well a

248 mineral density, trabecular bone volume, and cortical bone thickness compared with control littermate

249 f this cadaver study to determine an average cortical bone thickness in different tooth locations.

250 However, information about cortical bone thickness in various regions of the maxill

251 rtilage thickness decreased, and subchondral cortical bone thickness increased in the posterior tibia

252 Measurements were made of the cortical bone thickness of the harvested ramus graft and

253 in trabecular bone volume and a decrease in cortical bone thickness of the long bones.

254 ient mice expressed increased trabecular and cortical bone thickness producing mechanically stronger

255 A significant reduction in cortical bone thickness was also found in the sham/HP gr

256 ificantly reduced trabecular bone volume and cortical bone thickness, associated with increased osteo

257 ad increased bone mineral density, increased cortical bone thickness, higher rate of bone formation,

258 compared with bone mineral density (BMD) and cortical bone thickness.

259 signaling was critical for achieving proper cortical-bone thickness and stability.

260 There is an association between metacarpal cortical bone thinning and obstruction or incompressibil

261 a genetic disorder that is characterized by cortical-bone thinning, limb deformity, and fractures; t

262 the majority of BW is in the pore system of cortical bone, this parameter provides a surrogate measu

263 t enhanced the HyA staining of osteocytes in cortical bone tissue sections to the extent that the lac

264 y (SR-XRF), gadolinium was detected in human cortical bone tissue.

265 Decreases in cortical bone, trabecular bone, and whole-bone failure s

266 Micro-finite-element models for cortical bone, trabecular bone, and whole-bone section w

267 Decreases in cortical bone, trabecular bone, and whole-bone stiffness

268 becular bone volume and greater increases in cortical bone turnover, than did PTH(1-34).

269 ential, we acquired Raman spectra from human cortical bone using microscope- and fiber optic probe-ba

270 transverse and longitudinal orientations in cortical bone, using both crack-deflection/twist mechani

271 The material behavior of cortical bone varied in three ways: isotropic homogeneou

272 e, the cortical bone endosteum (CBE) and the cortical bone volume (CBV).

273 images of mouse paws for evaluation of joint cortical bone volume (JCBV) within close proximity of th

274 found that captivity induced an increase in cortical bone volume and muscle force, and a topographic

275 femoral cortical bone, as shown by unchanged cortical bone volume fraction (Ct.BV/TV), thickness (Ct.

276 receptor ligand trap prevents trabecular and cortical bone volume loss caused by myeloma, without inc

277 metry (DXA) scanning, and the trabecular and cortical bone volume was determined by microfocal comput

278 +/+), Postn(-/-) mice had a lower bone mass, cortical bone volume, and strength response to PTH.

279 n was -0.321, between BMI and the density of cortical bone was -0.250, and between BMI and trabecular

280 avimetric water content from human cadaveric cortical bone was created using NIRSI data obtained at s

281 In contrast, cortical bone was thickened with narrowing of the bone m

282 he medullary cavity and/or thickening of the cortical bone-was assessed.

283 scopic imaging (NIRSI) to monitor changes in cortical bone water content, an emerging biomarker relat

284 The dimension and volume of the neighboring cortical bone were adequate, and the augmented edentulou

285 veolar bone proper and more distant osteonal cortical bone were estimated.

286 l sites, regions of trabecular spongiosa and cortical bone were identified and segmented.

287 The maximum principal stress values for cortical bone were measured at the mesial, distal, bucca

288 d bone matrix chord length distributions for cortical bone were randomly sampled to create alternatin

289 us the anterior pillar is a hollow column of cortical bone, whereas in A. robustus it is a column of

290 e strength is determined by its outer shell (cortical bone), which forms by coalescence of thin trabe

291 there are no data on whether the porosity of cortical bone, which may play a greater role in bone str

292 We analyse metacarpal trabecular and cortical bone, which provide insight into behaviour duri

293 sults in exceptionally strong trabecular and cortical bones, whose density surpasses other reported m

294 Cortical bone width and trabecular thickness in Dicer(De

295 Severely affected lines also showed reduced cortical bone width.

296 ly, this new transport model of electrons in cortical bone will improve the relatively energy-indepen

297 quantify free and bound water components of cortical bone with a model-based numeric approach with u

298 apping bound and pore water in vivo in human cortical bone with practical human MR imaging constraint

299 r skeleton is compromised because of thinner cortical bone, with a low periosteal circumference and a

300 ases in BMD over 24 months at trabecular and cortical bone, with overall AE rates similar to those of