ライフサイエンスコーパス: cortical cataract

1 HFR polymorphisms via homocysteine levels to cortical cataract.

2 ependently associated with increased risk of cortical cataract.

3 and metabolic syndrome were associated with cortical cataract.

4 separately and jointly to increased risk of cortical cataract.

5 and inappropriate activity may contribute to cortical cataract.

6 that Ofl may be a model of human pulverulent cortical cataract.

7 ative importance of genes and environment in cortical cataract.

8 sed to determine the underlying liability to cortical cataract.

9 ay be related weakly to incident nuclear and cortical cataract.

10 s cell calcium has long been associated with cortical cataract.

11 size is a major risk factor for nuclear and cortical cataracts.

12 al volunteers and volunteers with nuclear or cortical cataracts.

13 0A4 ((-/-)) knockout mice develop late-onset cortical cataracts.

14 lear cataract, 1.62 (95% CI: 0.92, 2.85) for cortical cataract, 1.95 (95% CI: 0.48, 7.95) for posteri

15 Multivariate adjustment showed that pure cortical cataract (197 eyes) was significantly associate

16 In studies of cortical cataract, a severity score representing the are

17 s) and 95% confidence intervals for incident cortical cataract, after adjusting for age, sex, smoking

18 effects are important in the development of cortical cataract and involve the action of dominant gen

19 due to two novel PAX6 mutations; progressive cortical cataract and lamellar cataract with lens sublux

20 aA-crystallin subunits resulted in posterior cortical cataracts and abnormalities associated with the

21 the PP1-treated lenses showed development of cortical cataract, and the average area of opacity was j

22 The CRYalphaA(N101D) mice developed cortical cataract at about 7-months of age relative to C

23 will be 167,000-830,000 additional cases of cortical cataract by 2050.

24 Risk of cortical cataract by contrast fell with increasing birth

25 lear (NSC), posterior subcapsular (PSC), and cortical cataract (CC), using the new WHO Simplified Cat

26 In aged mice, most subcapsular and cortical cataracts colocalize with accumulations of nucl

27 Cortical cataracts develop in FE65L1 knockout (KO) mice

28 In multivariate analysis, age, sex (male), cortical cataract, diabetes, nuclear cataract, and forme

29 t that repression of estrogen action induces cortical cataract formation because estrogen is required

30 felodipine or nifedipine induces progressive cortical cataract formation with time, in association wi

31 he Salisbury Eye Evaluation Study, a digital cortical cataract grading algorithm was used to capture

32 Prevalence of significant cortical cataract (>/=5% of lens area) was similar in mo

33 The association between PXS and cortical cataract, however, did not persist after furthe

34 and serum homocysteine levels with incident cortical cataract in an older population.

35 Cortical cataract in humans is associated with Ca2+ over

36 ay be a therapeutic target to reduce risk of cortical cataract in persons carrying genetic risk.

37 risk of development of mild nuclear or mild cortical cataracts in participants not taking Centrum (P

38 ole for vitamin C in diminishing the risk of cortical cataracts in women aged <60 y and for carotenoi

39 idence interval [CI], 2.07-3.70; P < 0.001); cortical cataract increase of 5% or more in lens opacity

40 Modeling suggested liability to cortical cataract is explained by additive and dominant

41 ilure and the development of subcapsular and cortical cataracts is observed in Mbnl3(DeltaE2) mice.

42 The current genome scan for age-related cortical cataracts may lead to identification of novel g

43 ll of which exhibit posterior nuclear and/or cortical cataracts of variable severity.

44 taract status graded by the Wilmer protocol (cortical cataract: opacity >or=4/16; nuclear cataract gr

45 no follow-up data or DNA or who had previous cortical cataract or cataract surgery, 757 participants

46 levels were associated with a 3-fold risk of cortical cataract (OR = 3.74; 95% CI = 1.79-7.80).

47 aract: OR, 0.62; 95% CI, 0.43-0.88; and mild cortical cataract: OR, 0.77; 95% CI, 0.63-0.95.

48 aract: OR, 0.62; 95% CI, 0.43-0.90; and mild cortical cataract: OR, 0.80; 95% CI, 0.65-0.99.

49 phaB and betaB1 was significantly related to cortical cataract (P <or= 0.05).

50 , 1.73; 95% CI, 1.10-2.72) cataract, but not cortical cataract (P = 0.64); each millimeter increase i

51 XS had a significantly greater prevalence of cortical cataract (P=.02) and nuclear cataract (P < .000

52 oled OR 1.93, 95% CI 1.49-2.49) but not with cortical cataract (pooled OR 1.08, 95% CI 0.90-1.30).

53 me ocular exposure to ultraviolet B light on cortical cataract risk for each lens region was examined

54 haplotypes show a stronger association with cortical cataract (rs3761382, P = 0.002, OR = 2.1; rs130

55 t may not entirely explain the variations in cortical cataract severity across the lens.

56 The lower nasal regions had the highest cortical cataract severity in both the right and left ey

57 In the ER Delta 3 transgenic mice, cortical cataracts spontaneously form in ER Delta 3 fema

58 io (0.43; 95% CI: 0.2, 0.93) of developing a cortical cataract than was an intake <140 mg/d, and use

59 explained 26% and 37% and age 16% and 11% of cortical cataract variance in clinical and digital gradi

60 Five-year incidence of cortical cataract was 9.9% in statin users and 7.5% in n

61 Cortical cataract was assessed using the slit-lamp-based

62 h analysis showed that the genetic effect on cortical cataract was partially mediated via homocystein

63 To identify susceptibility loci for cortical cataracts, we genotyped a subset of families (1

64 Estimates of the broad sense heritability of cortical cataract were 58% (95% confidence interval [CI]

65 ular exposure to ultraviolet B radiation and cortical cataract were derived from a population-based s

66 studies, posterior subcapsular, nuclear, and cortical cataracts were associated with visual impairmen

67 etermine whether age-related subcapsular and cortical cataracts were linked to the failure of lens fi

68 In one phakic member, the cortical cataracts were punctate and vacuolated.

69 s between hyperopia and incident nuclear and cortical cataracts were unchanged.

70 is indicated that by 2050, the prevalence of cortical cataract will increase above expected levels by