ライフサイエンスコーパス: cortisol

1 red with heart rate variability and salivary cortisol.

2 ted with heart rate variability and salivary cortisol.

3 provided hair samples that were assayed for cortisol.

4 ure enzymatic assays, and it is specific for cortisol.

5 cortisone to the active glucocorticoid (GC) cortisol.

6 aldosterone and also acts as a receptor for cortisol.

7 med to immobilize the antibodies specific to cortisol.

8 n towards a supportive ingroup, regulated by cortisol.

9 f 0.005 fg/mL for the sensitive detection of cortisol.

10 atic skin leading to localized deficiency of cortisol.

11 highly-sensitive quantification of salivary cortisol.

12 variation in blood pressure, heart rate, and cortisol.

13 of 20beta-dihydrocortisol (20beta-DHF) from cortisol.

14 stressful situation, the human body produces cortisol.

15 developed asymptomatic, low serum levels of cortisol.

16 le to those of peak expiratory flow or serum cortisol.

17 directly correlated with the stress hormone cortisol.

18 s of their measured activities, aldosterone, cortisol, 11-deoxycorticosterone, corticosterone, 11-deo

19 Salivary cortisol (6.8 nmol/l, P < 0.001) and heart rate (7.2 bea

20 ed vulnerability to depression (high morning cortisol(6-9) and negative self-cognitions during low mo

21 This research explains how increases in cortisol, a biomarker of stress, disrupts navigation-rel

22 Cortisol, a key product of the stress response, has crit

23 Dysregulation in cortisol, a stress hormone that is the primary output of

24 emotional stress related hormones including cortisol, adrenaline, and serotonin were abnormally obse

25 olution, or other clinical outcomes based on cortisol, aldosterone, and ascorbic acid concentrations.

26 nd other clinical outcomes based on baseline cortisol, aldosterone, and ascorbic acid concentrations.

27 .13; 95% CI, 1.00-1.27; P = 0.04), but total cortisol, aldosterone, and ascorbic acid were not.Conclu

28 orrelated with serum hormone concentrations (cortisol and aldosterone), hepatobiliary enzyme levels,

29 Here, we examined associations between hair cortisol and children's hippocampal and ACC structure, i

30 Plasma levels of cortisol and chromogranin-A were determined.

31 Glucocorticoids (cortisol and corticosterone) and their inactive versions

32 Our results revealed that higher cortisol and CRP levels were significantly associated wi

33 ontaminants commonly found in saliva such as cortisol and dopamine.

34 pecificity was associated with lower morning cortisol and fewer negative self-cognitions during low m

35 battery, overnight hourly blood sampling for cortisol and genetic assessment.

36 HIIT suppressed cortisol and growth hormone responses, but not catechola

37 er acclimation (adrenocorticotropic hormone, cortisol and growth hormone) increased in spring in both

38 a unique endocrine milieu comprising minimum cortisol and high aldosterone, growth hormone (GH), and

39 aracterizing SWS (mainly by further reducing cortisol and increasing aldosterone levels) and reduces

40 e imaging data; n = 41 with both parent hair cortisol and magnetic resonance imaging data).

41 nd surface area (n = 37 with both child hair cortisol and magnetic resonance imaging data; n = 41 wit

42 fluence of two major stress neuromodulators, cortisol and noradrenaline, on loss aversion during fina

43 1 (11beta-HSD1) enzyme converts cortisone to cortisol and participates in the regulation of glucocort

44 dy, we investigated the associations of hair cortisol and plasma C-reactive protein (CRP) with the lo

45 biomarkers of condition, including baseline cortisol and testosterone levels, body morphology and st

46 In addition, cortisol and testosterone negatively interacted in predi

47 rn of effects was observed across endocrine (cortisol and testosterone), psychological (feeling in co

48 We show that corticosterone and cortisol and their less active precursors 11-dehydrocort

49 he Perceived Stress Scale (PSS) and salivary cortisol) and their relationship with rates of cognitive

50 .0076 ng/uL for aldosterone, corticosterone, cortisol, and beta-estrone, respectively, and with an av

51 resent study combined neuroimaging, salivary cortisol, and blood markers of inflammation and metaboli

52 ess and anxiety, breast milk intake and milk cortisol, and infant behavior and growth.

53 growth factor I, triglycerides, cholesterol, cortisol, and leptin, were measured after an overnight f

54 ss did not significantly correlate with hair cortisol, and there was no evidence to suggest that indi

55 s or gold-coated glass slides decorated with cortisol antibodies as the capture substrates.

56 However, despite the popularity of cortisol as a biomarker for stress and adversity, little

57 although delta cortisol (change in baseline cortisol at 60 min of < 9 mug/dL) after cosyntropin (250

58 3.13; 95% CI: -5.9, -0.3) and lower hindmilk cortisol at HV1 (Delta = -44.5%; 95% CI: -76.1%, -12.9%)

59 A bigger cortisol awakening response (CAR) was weakly associated

60 of cognitive tasks, disrupted sleep and the cortisol awakening response (CAR), depending on whether

61 xysteroid dehydrogenase type 2 to inactivate cortisol before it reaches the fetus, leading to higher

62 ctors can advance algorithm developments for cortisol biosensing systems to mitigate stress-based ill

63 A non-faradaic label-free cortisol biosensor was demonstrated using MoS2 nanosheet

64 In this work, we present a cortisol biosensor which relies on a highly sensitive te

65 1beta-hydroxylase (CYP11B1), which catalyzes cortisol biosynthesis and is highly homologous to CYP11B

66 teroidogenesis pathway that lead to impaired cortisol biosynthesis.

67 uries and death, and reduced saliva and hair cortisol, both biomarkers for stress.

68 Of interest, PGE2 and cortisol, both well-demonstrated stimulants of COX-2 exp

69 or simultaneous detection of insulin (I) and cortisol (C) biomarkers that can enhance the ability to

70 can reliably diagnose CIRCI, although delta cortisol (change in baseline cortisol at 60 min of < 9 m

71 Cortisol, clinical symptoms and variation in genes, NR3C

72 Increased cortisol-collected during the 2nd, but not the 3rd, trim

73 rcise (SBE), and saliva after exercise (SAE) cortisol concentration (AP-SBE: p = 0.0017, AP-SAE: p =

74 tary-adrenal axis activity, measured by hair cortisol concentration (HCC), is associated with microst

75 to females (p = 0.0559), and significant SAE cortisol concentration differences were also recorded be

76 Trier Social Stress Test (n = 444), and (c) cortisol concentration in hair (n = 1210).

77 ality-of-life domains, disease activity, and cortisol concentration in hair.

78 d relationship, a human pilot study examined cortisol concentration in sweat and saliva samples colle

79 Hair cortisol concentration may be an informative biomarker l

80 A significantly greater AP cortisol concentration was detected in males compared to

81 Higher hair cortisol concentration was significantly associated with

82 Chronic stress-as indexed by hair cortisol concentration-may represent an important mechan

83 cortisol in a linear fashion with respect to cortisol concentration.

84 alter blood pressure, heart rate, or plasma cortisol concentrations (all Poverfeeding x sleep = NS).

85 Research examining maternal cortisol concentrations across pregnancy and offspring n

86 Post-confinement cortisol concentrations and gene expression of corticotr

87 Hair cortisol concentrations correlated with stress (r(s) = 0

88 Maternal cortisol concentrations during pregnancy were significan

89 of picomolar (pM) insulin and nanomolar (nM) cortisol concentrations in a single microliter sample dr

90 l-being, sex factors, athletic activity, and cortisol concentrations in various biofluids to predict

91 rwise inactivates cortisol, sustaining tumor cortisol concentrations to stimulate GR and enzalutamide

92 Maternal cortisol concentrations were assessed serially over 4 da

93 no effect of MCH on fetal plasma/lung tissue cortisol concentrations, nor genes regulating glucocorti

94 mance and was therefore selected to quantify cortisol content in biological fluids (urine and serum).

95 is the major receptor for the stress hormone cortisol (corticosterone in rodents) and is widely expre

96 ry cortisol levels and calculated a salivary cortisol cut-off value for screening adrenocortical func

97 Salivary cortisol cut-off values were 0.015mug/dL for plasma cort

98 Beyond the effects of cortisol, demographics and clinical symptoms, NR3C1 vari

99 Notably, cortisol demonstrated an overrepresentation of associati

100 ase (HRP)-labeled sandwich assay whereas the cortisol detection relies on an alkaline phosphatase (AL

101 nd-held device successfully exhibited a wide cortisol-detection range from 3 pg/mL to 10 mug/mL, with

102 rforming sensitive LFIA analysis of salivary cortisol down to 0.4 ng/mL directly onboard the Internat

103 mpanzees experienced their highest levels of cortisol during cycling (versus lactation), and this eff

104 Maternal cortisol during pregnancy has the potential to influence

105 Normative variation in maternal cortisol during pregnancy is associated with the coordin

106 Maternal cortisol during pregnancy is related to newborn amygdala

107 cific distress, and 24-h ambulatory salivary cortisol) during the 2nd and 3rd trimesters.

108 agal tone and heart rate variability, alters cortisol dynamics during stress and heightens reactivity

109 alamic-pituitary-adrenal axis regulation and cortisol dynamics, the autonomic nervous system, and gen

110 on corticosteroids, as well as to those with cortisol elevations due to medical or psychiatric condit

111 rhythm and a significant linear increase in cortisol, even after controlling for changes in dominanc

112 (NFATs) or adenomas causing mild autonomous cortisol excess (MACE), but their natural history is unc

113 al of the beneficial effects, with long-term cortisol exposure becoming maladaptive, which can lead t

114 ly to the transcriptomic response to chronic cortisol exposure, mediating the upregulation of proinfl

115 aches the fetus, leading to higher levels of cortisol exposure.

116 g to progressive dysregulation and increased cortisol exposure.

117 Although the initial rise in cortisol follows a large surge in adrenocorticotropic ho

118 A detailed comparison of sodium, lactate and cortisol from saliva is reported, demonstrating the pote

119 ul sampling was determined when the ratio of cortisol from the adrenal vein to the level of cortisol

120 significant variation in telomere length and cortisol functioning was observed at the neighborhood le

121 Circadian phase and amplitude of melatonin, cortisol, ghrelin, leptin, and glucose were not differen

122 le DLMO (p = 0.049), higher evening salivary cortisol, greater insomnia symptoms and greater sleep va

123 lammatory lipids and stress hormones such as cortisol, have been recognized as key factors in amyloid

124 Salivary cortisol (hypothalamic pituitary axis), heart rate varia

125 e, we examine age-related changes in urinary cortisol in a 20-y longitudinal study of wild chimpanzee

126 ate technique, which shows the separation of cortisol in a linear fashion with respect to cortisol co

127 a biosensor for analysing salivary levels of cortisol in astronauts, a marker of chronic stress.

128 n immune cell numbers were mostly similar to cortisol in direction but smaller in intensity and durat

129 hermore, combinatorial detection of IL-6 and Cortisol in human sweat was established with minimal cro

130 rtisol from the adrenal vein to the level of cortisol in the inferior vena cava >= 5.

131 We demonstrate SERS-based detection of cortisol in the physiologically relevant range using col

132 belled cortisol is added to compete with the cortisol in the sample, for the capture Ab binding sites

133 Furthermore, we identified hsd11b2, a cortisol inactivating gene, as chronic stress-responsive

134 nging, increased object exploration, smaller cortisol increases) compared to No SI subjects.

135 was negatively correlated to stress-induced cortisol increases.

136 to the TSST measuring the levels of salivary cortisol, IOP, and heart rate before, immediately after,

137 Cortisol is a biomarker for stress monitoring; however,

138 Horseradish peroxidase (HRP)-labelled cortisol is added to compete with the cortisol in the sa

139 For this reason, cortisol is also called "the stress hormone" and is cons

140 Cortisol is an important steroid hormone in human physio

141 We previously showed that cortisol is lower in obese pregnancy.

142 s have demonstrated that plasma clearance of cortisol is markedly reduced during critical illness, ex

143 The end product of this pathway - cortisol - is secreted in a pulsatile pattern, with chan

144 sitive correlations between AP cortisol, SAE cortisol, K10 scores, and fat intake among female partic

145 x metalloproteinases mmp-9 and mmp-13, while cortisol led to stronger upregulation of the gluconeogen

146 nificant relationships were observed between cortisol level and immune function, nor between family i

147 family income during ontogeny, adult height, cortisol level and immune response in women.

148 cortisol signaling in males, or increase of cortisol level in females, decreased or increased the nu

149 ironmental factors that affect physiological cortisol level, which include individual mood and dietar

150 ntranasal insulin also increased circulating cortisol levels (F=12.78, P0.001).

151 kening cortisol levels, the mean increase in cortisol levels (MnInc) and total cortisol secretion (AU

152 the correlation between plasma and salivary cortisol levels and calculated a salivary cortisol cut-o

153 No relationship was found between salivary cortisol levels and conversion rate to dementia.

154 Endophenotypic analyses using peripheral cortisol levels and neuroimaging paradigms showed that m

155 ficant positive correlation between salivary cortisol levels and plasma cortisol levels in all patien

156 Acute elevations in cortisol levels are beneficial to promoting survival of

157 l cut-off values were 0.015mug/dL for plasma cortisol levels below 3mug/dL (sensitivity 83%, specific

158 There was a significant linear increase of cortisol levels between the start and end of each IBL st

159 Despite prednisolone and cortisol levels commonly being used as adherence markers

160 ations or abnormalities in the physiological cortisol levels control acute and chronic stress respons

161 or waking cortisol levels, and 5.5% for peak cortisol levels following a stressor.

162 between salivary cortisol levels and plasma cortisol levels in all patients, patients under age 3, a

163 pal region most closely associated with hair cortisol levels in childhood.

164 pt studies were performed to detect salivary cortisol levels in human subjects with high and low risk

165 Detection of cortisol levels in human sweat samples has also been inv

166 mics of melatonin suppression and changes in cortisol levels in humans in response to light exposure

167 evels were positively correlated with plasma cortisol levels in pediatric asthmatic patients.

168 The ability to monitor cortisol levels in the physiological range is key in dia

169 ere current methodology for determination of cortisol levels relies on instrumentation that requires

170 one levels return to near basal levels while cortisol levels remain raised as a result of increased a

171 minant to arginine vasopressin-dominant, and cortisol levels remain raised due at least in part to de

172 During acute stress, cortisol levels rise and pulsatility is maintained.

173 ightened aggression and decreased whole-body cortisol levels suggesting that they are dominant.

174 s experiencing decreased appetite had higher cortisol levels than subjects in the other two groups, a

175 nversion rates to dementia but high salivary cortisol levels were associated with RLCQ scores and poo

176 jective measures of auditory performance and cortisol levels were collected on 3 Friday nights over t

177 No differences in cortisol levels were found.

178 Plasma and salivary cortisol levels were measured from 8:00 am to 10:00 am i

179 Cortisol levels were measured from plasma samples pre- a

180 erts were not a response to stress as canine cortisol levels were not significantly changed.

181 Salivary cortisol levels were positively correlated with plasma c

182 We found that higher hair cortisol levels were specifically related to lower CA3-D

183 s of 6% for telomere length, 3.4% for waking cortisol levels, and 5.5% for peak cortisol levels follo

184 sychological state, breast milk intake, milk cortisol levels, and infant behavior and growth.

185 ificant changes in IOP, heart rate, salivary cortisol levels, and STAI scores.

186 Women from wealthier families had lower cortisol levels, and women from the highest family incom

187 Conventional methods of quantifying stress (cortisol levels, heart rate/heart rate variability) requ

188 measurement indices were derived: awakening cortisol levels, the mean increase in cortisol levels (M

189 se correlations were discovered among plasma cortisol levels, TSC22D3 expression in circulating leuko

190 icted testosterone only among men with lower cortisol levels.

191 at was strongest among those with the lowest cortisol levels.

192 ological measures of heart rate and salivary cortisol levels.

193 cortisone led to an acute increase in plasma cortisol levels.

194 elatonin onset (DLMO)), and evening salivary cortisol levels.

195 tion of these lipid classes and reduce acute cortisol levels.

196 We investigated the use of salivary cortisol measurements as a simple, noninvasive method fo

197 oup but neither the RLCQ scores nor salivary cortisol measures were different between groups.

198 ross hippocampal subfields, and whether hair cortisol mediated associations between socioeconomic bac

199 tive stress and gut microbial diversity, and cortisol metabolism.

200 ain raised due at least in part to decreased cortisol metabolism.

201 essed expression and activity of the primary cortisol-metabolizing enzymes in the liver and kidney.

202 Increased NOP in response to elevated cortisol might suggest a compensatory mechanism in the b

203 hing's syndrome and a mean 24-h urinary free cortisol (mUFC) of at least 1.5 times the upper limit of

204 escales: (a) diurnal fluctuation in salivary cortisol (n = 400), (b) salivary cortisol reactivity and

205 Hair cortisol (N = 4761) and plasma CRP (N = 5784) were measu

206 h either hydrocortisone or placebo for total cortisol (odds ratio [OR], 1.09; 95% confidence interval

207 (250 mug) administration and a random plasma cortisol of < 10 mug/dL may be used by clinicians.

208 vo effects of adrenaline, noradrenaline, and cortisol on number and functionality of porcine blood im

209 OR, 1.07; 95% CI, 1.00-1.13; P = 0.70), free cortisol (OR, 1.20; 95% CI, 1.04-1.38 vs. OR, 1.16; 95%

210 We tested differences in cortisol output across nine aspects of social disadvanta

211 ng of reward is already related to increased cortisol output and depression severity in preschoolers.

212 lation-based Texas Twin Project, we measured cortisol output at three different timescales: (a) diurn

213 and adversity, little is known about whether cortisol output differs in children being raised in soci

214 Higher total cortisol output following a stressor was associated with

215 put, as measured in saliva; otherwise, child cortisol output was unrelated to any other aspect of soc

216 gher concentrated poverty had higher diurnal cortisol output, as measured in saliva; otherwise, child

217 vantaged and disadvantaged children in their cortisol output.

218 ed to cumulative glucocorticoid levels (hair cortisol), parenting stress, and performance on memory t

219 included in the IPD meta-analysis of diurnal cortisol patterns with crystallised and fluid cognitive

220 , master clock markers (plasma melatonin and cortisol), plasma triglycerides, or clock gene expressio

221 gh DNA methylation in hypercortisolemia with cortisol-producing adenoma (CPA), and to investigate a p

222 abergoline or pasireotide, or both, controls cortisol production in up to 40% of patients.

223 In turn, cortisol production is affected by senescence of the hyp

224 hypothesise that this may reflect diminished cortisol production to psychological stress as the disea

225 s disease, a disorder arising from excessive cortisol production.

226 tration, despite similarities in circulating cortisol profiles.

227 thesis testing and for evaluation of morning cortisol profiles; and 5) identify measures that best di

228 The cortisol quantification is performed by colorimetric det

229 By contrast, hALCs synthesized cortisol rather than T.

230 racterized by high, prolonged stress-induced cortisol reactivity and emotional reactivity in toddlerh

231 measures of self-regulation: stress-induced cortisol reactivity and fear-elicited emotional reactivi

232 in salivary cortisol (n = 400), (b) salivary cortisol reactivity and recovery after exposure to the T

233 sed pubertal stage via nurse examination and cortisol reactivity to the Trier social stress test for

234 n situ monitoring of human stress levels and cortisol-related disorders (e.g. Cushing's syndrome and

235 Swabbing led to a smaller change in cortisol release and behaviour on the first day of analy

236 ted a significant stress-induced increase in cortisol release and negative affect, the hyper-response

237 n was prevalent between nutrition, mood, and cortisol release.

238 he stress group (including both Low and High cortisol responders) showed reduced P300 amplitude to ta

239 examined the concurrent associations between cortisol response following a stressor, functional brain

240 reported child depression severity and child cortisol response following stress were also measured.

241 We used sci-fate to study the cortisol response in >6,000 single cultured cells.

242 rception at 6 weeks and 1 year, and salivary cortisol response to a simulated anaphylaxis scenario at

243 ial Stress Test (TSST) is a tool to evaluate cortisol response to psychologic stimulation based on th

244 Although cortisol response to stress is essential for survival, a

245 onse, groups characterized by hyper and mild cortisol response were both associated with more negativ

246 Relative to the group showing a moderate cortisol response, groups characterized by hyper and mil

247 e memory activation has been found to dampen cortisol responses and improve mood in humans(4) and to

248 Significant positive correlations between AP cortisol, SAE cortisol, K10 scores, and fat intake among

249 or T biosynthesis, synthesized T rather than cortisol, secreted steroid hormones in response to dibut

250 ncrease in cortisol levels (MnInc) and total cortisol secretion (AUC(G)).

251 still controversial due to the complexity of cortisol secretion mechanisms and their circadian cycles

252 ne regulator of the stress axis that reduces cortisol secretion.

253 ants suggests glucose involvement in blubber cortisol sensitivity.

254 Pigs receiving cortisol showed strongly decreased adaptive immune cell

255 Under CBL conditions cortisol showed trimodal changes with an initial linear

256 steroid-17,20-desmolase pathway cleaves the cortisol side chain, forming pro-androgens predicted to

257 B. adolescentis 20beta-HSDH could regulate cortisol side-chain cleavage by limiting pro-androgen fo

258 teroid dehydrogenase (20beta-HSDH) regulates cortisol side-chain cleavage by reducing the C-20 carbox

259 Inhibition of cortisol signaling in males, or increase of cortisol lev

260 Hair cortisol significantly mediated associations between par

261 Analysis of cortisol solutions in a complex matrix (bovine serum alb

262 Significant elevations of IOP, salivary cortisol, STAI scores, and heart rate occurred after ind

263 rtal stage were associated with increases in cortisol stress reactivity for postinstitutionalized you

264 ed by crowding stress or exposed to elevated cortisol stress, both of which activate glucocorticoid r

265 2 (11beta-HSD2), which otherwise inactivates cortisol, sustaining tumor cortisol concentrations to st

266 h selectivity against the closely homologous cortisol synthase (CYP11B1).

267 ed by colorimetric detection of HRP-labelled cortisol, through optical absorption at 450nm, using a C

268 ated with a decrease in the ratio of urinary cortisol to creatinine in children younger than 8 years

269 The identified pathway from maternal cortisol to higher internalizing symptoms in girls via a

270 hat of larvae with a GR, suggesting that the cortisol-treated larvae develop GR resistance.

271 and paradoxically, that the transcriptome of cortisol-treated larvae is more like that of larvae lack

272 9-) larvae and consistently overexpressed in cortisol-treated larvae was klf9.

273 dependent gene expression in both normal and cortisol-treated larvae.

274 nder both normal conditions and with chronic cortisol treatment, we find that GR mediates most of the

275 s often done by measuring 24-hour urine free cortisol (UFC) excretion.

276 subjects in the other two groups, and their cortisol values correlated inversely with the ventral st

277 oses of either adrenaline, noradrenaline, or cortisol via i.v. infusion for 48 h.

278 Higher hair cortisol was also associated with greater caudal ACC thi

279 Elevated maternal cortisol was associated with higher internalizing sympto

280 thermore, when controlling for testosterone, cortisol was associated with increased ingroup-love.

281 Elevated maternal cortisol was associated with stronger amygdala connectiv

282 Higher night time cortisol was associated with worse fluid ability (standa

283 Cortisol was chosen as a model analyte.

284 control manipulation a week later; salivary cortisol was measured throughout to assay stress reactiv

285 Cortisol was most frequently measured (N = 136), usually

286 Despite being the most abundant steroid, cortisol was not consistently associated with predation

287 istically signifies a direct relationship to cortisol was not present.

288 Elevated free cortisol was significantly associated with 90-day mortal

289 rement of blood prednisolone with or without cortisol was used in eight studies as a measure of oral

290 Subjective sleepiness, melatonin and cortisol were assessed hourly.

291 Elevations in cortisol were associated with more negative ratings of s

292 Morning serum levels of cortisol were in the normal range at baseline and did no

293 e cell proportions, cytokines, CRP and serum cortisol were measured at baseline and during the exam p

294 circulating adrenocorticotropic hormone and cortisol were observed.

295 he final step generating the steroid hormone cortisol, which controls stress and immune responses and

296 cation level was associated with higher hair cortisol, which in turn was associated with smaller volu

297 one is converted by 11beta-HSD1 to active GC cortisol, which is responsible for delayed wound healing

298 stronger effects on immune system genes than cortisol, which was characterized by upregulation of fkb

299 ed to sustained improvements in urinary free cortisol, with an acceptable safety and tolerability pro

300 avage by reducing the C-20 carboxyl group on cortisol, yielding 20beta-dihydrocortisol.