ライフサイエンスコーパス: covariation

1 are often residues that display evolutionary covariation.

2 traits that give rise to their strong global covariation.

3 nmeasured traits are required to explain LES covariation.

4 hifts in amino acid propensities due to site covariation.

5 s result in robust insights about phenotypic covariation.

6 sounds orthogonal or oblique to experienced covariation.

7 fect on a cell's output of manipulating such covariation.

8 rrors suffices to create all of the observed covariation.

9 strate high intraspecific variation in shape covariation.

10 ary across the strains, they exhibit minimal covariation.

11 hic data we identified two distinct modes of covariation.

12 olutionarily relevant patterns of amino acid covariations.

13 post-transcriptional regulation in defining covariations.

14 merely has insufficient variation to detect covariations.

15 shows several code-like protein-DNA sequence covariations.

16 ral key patterns of stomatal-hydraulic trait covariations.

17 omputational method, R-scape (RNA Structural Covariation Above Phylogenetic Expectation), that quanti

18 We also show covariation across different types of justice intuitions

19 tic dimensionality reduction, we investigate covariation across learning trajectories with few assump

20 We highlight patterns of covariation across levels of organisation and conclude w

21 Modelling results show substantial covariation across tasks, such that an entirely unobserv

22 We show strong regional patterns of trait covariation across the shared ranges of Th. couchii and

23 ndings suggest that, in healthy populations, covariation across these complex multidimensional behavi

24 We use amino acid evolutionary covariation across these ORs to define restraints on str

25 sing PCA, a color space was derived from the covariation, across voxels, in the responses to differen

26 We demonstrate that variability and covariation also apply to the biophysical properties of

27 ies often reported evidence of weak negative covariation, although more complicated patterns were als

28 that less-complex societies exhibit stronger covariation among behavioural characteristics, resulting

29 ptations in the absence of information about covariation among characteristics.

30 s of interspecific patterns of variation and covariation among characters describing the stem, cup, a

31 by RNase structure probing and by nucleotide covariation among closely related group 2 coronaviruses,

32 s on cortisol coregulation suggests stronger covariation among distressed partners.

33 to unpick subtle changes in variability and covariation among key genes.

34 -standing hypothesis by assessing geographic covariation among pollinator reliability, outcrossing ra

35 ographic rates, using simulated and observed covariation among rates.

36 The covariation among replicates of the three species densit

37 also providing a platform for assessments of covariation among root, leaf, and wood traits, the role

38 between growing seasons can lead to positive covariation among virus species.

39 this latent variable, by producing positive covariation among winter demographic rates, depicts a me

40 Genome-wide covariation analyses of pretreatment virus sequences fro

41 and is supported by combined mutagenesis and covariation analyses.

42 We present Coordinate Covariation Analysis (COCOA), a computational framework

43 Here, we combined covariation analysis and structure-based prediction to a

44 However, covariation analysis does reveal a weaker although signi

45 This reveals that covariation analysis identifies other types of structura

46 Covariation analysis is used to identify those positions

47 Covariation analysis provides limited support for basic

48 ectation), that quantitatively tests whether covariation analysis supports the presence of a conserve

49 y phenotype, as well as an evolutionary rate covariation analysis, generated lists of modifying genes

50 d coarse-grained MD simulations and sequence covariation analysis, we characterized the interface bet

51 airing constraints derived from phylogenetic covariation analysis.

52 that sensory systems are able to detect such covariation and adapt to reduce redundancy, leading to m

53 ure improvements; for example, incorporating covariation and immunological constraints will permit mo

54 This covariation and interaction may partially explain differ

55 e play a dominant role in shaping amino acid covariation and that computational protein design method

56 fied using a combination of protein sequence covariation and TMH binding surfaces predicted from sequ

57 t miRNAs naturally induce transcriptome-wide covariations and compare the relative importance of nucl

58 t insights into the interpretation of muscle covariations and their role in movement control.

59 We conclude that covariation (and probably a tightly controlled coregulat

60 f selection, estimated genetic variation and covariation, and predicted the response to selection for

61 ces to robustly assess the extent of residue covariation, and the larger the protein family, the more

62 uding the same latitudinal gradient in trait covariation, and the potential 'escape' from the arms ra

63 -to-spike correlations or slow across-trials covariations, and both were equally positive and negativ

64 pairs that have variation but no significant covariation are prevented from occurring.

65 Pairwise sequence covariations are a signal of conserved RNA secondary str

66 The validation of covariation as a predictive tool will be dependent on mo

67 enol A (BPA) was identified by chemical:gene covariation as the most impactful estrogenic chemical ac

68 d or adapted to encode the natural kinematic covariations associated with prehension described by a l

69 global-scale models may poorly describe LES covariation at non-global scales.

70 statistical coupling analysis (SCA) to infer covariations at various locations using a family of evol

71 ouplings between residue pairs have rendered covariation-based contact prediction a viable means for

72 s, however, little evidence of the predicted covariation between an animal's olfactory cues and its g

73 human subjects learned to shape patterns of covariation between arbitrary pairs of hand and forearm

74 thermore, our records show that the observed covariation between atmospheric CO2 concentration and ab

75 ariate models that account for the pervasive covariation between biological factors and extinction ar

76 an randomization (MR) accounting for genetic covariation between BMI and WHR, and we assessed what pr

77 We then quantify how covariation between both infection parameters measured d

78 orrelation analyses (sCCAs) to determine the covariation between brain imaging metrics of WM-network

79 We sought to discover linked patterns of covariation between brain structural development and a w

80 Differential patterns of covariation between combat veterans with and without PTS

81 mpare amounts of intraspecific variation and covariation between cranial shape and ecological variabl

82 iases have on individual measures and on the covariation between different constructs.

83 d States, paying particular attention to how covariation between ecological benefits and economic cos

84 associated polygenic variation also captured covariation between environmental exposures and children

85 Extensive covariation between floral traits and mating system amon

86 on analysis to discover distinct patterns of covariation between measures of brain organization (brai

87 Many studies have demonstrated covariation between muscle activations during behavior,

88 n task variables, this finding suggests that covariation between muscle activity is not solely driven

89 n biotic interactions, may commonly underlie covariation between native and non-native faunas, especi

90 gitudinal data to extract modes with maximum covariation between neuroimaging and non-imaging measure

91 ative sample (n = 6,710), we find widespread covariation between offspring trait-associated polygenic

92 Strong covariation between our new composite ITCZ-stack and Nor

93 carbon (C) cycles; yet, the demonstration of covariation between overstory tree genetic-based traits

94 pes enable us to identify subtle patterns of covariation between peptide sequence positions; analysis

95 n utilized is to examine overall patterns of covariation between phenotypic variables of interest, su

96 in cross-study synthesis, due to ubiquitous covariation between replication, variance and plot size.

97 Moreover, the strong covariation between residues in matrix and capsid at the

98 Poorly integrated plant CCDs (i.e. low covariation between scent compounds) support the notion

99 No covariation between self-relatedness and peripheral auto

100 we demonstrate conserved patterns of simple covariation between sequence evolution, codon usage, and

101 is does reveal a weaker although significant covariation between sets of nucleotides that are in prox

102 Nevertheless, population covariation between sexually antagonistic traits remaine

103 raspecific variation in both species, but no covariation between shape and climate in humans, contras

104 s in diffuse light fields that eliminate the covariation between surface orientation and intensity, a

105 Thus, we hypothesize that there has been covariation between the amount of DNA gained by transpos

106 f their DNA binding sites, investigating the covariation between the protein sequence and the sequenc

107 3D geometric morphometric analysis of shape covariation between the trapezial and proximal first met

108 Lastly, we found significant covariation between the volatile compounds and bacterial

109 We investigated covariation between trait-associated polygenic variation

110 and how this would affect interpretation of covariation between transcriptional profiles and other p

111 ed pattern and mechanism of positive genetic covariation between virulence and pathogen load are cons

112 We also find evidence for positive genetic covariation between virulence and pathogen load, a proxy

113 Instead, the preferentially strong covariation between VM and VL is consistent with the con

114 However, covariation between VM and VL was also stronger than the

115 actions on task variables, we found that the covariation between VM and VL was stronger than their co

116 we found weak but significant trial-to-trial covariations between V1 activity and behavioral choices,

117 Because of covariation, blood loss, blood transfusion, and complica

118 We verify predicted theoretical covariations by contrasting empirical data and provide t

119 This covariation can arise from multiple factors, including s

120 Finally, we demonstrate that the patterns of covariation can be generalized to quantifiable biologica

121 reliable modes of brain-behavior-environment covariation (canonical r(discovery) = .21 to .49, canoni

122 lationship between the resulting gray matter covariation components and mutual eye gaze.

123 ions between bout length and two gray matter covariation components.

124 Covariation concomitantly increases the frequencies of g

125 he method, named CaCoFold (Cascade variation/covariation Constrained Folding algorithm), predicts a n

126 Furthermore, we give examples of complex covariation created by simple regimes of combined direct

127 to lack covariation support do have adequate covariation detection power, providing additional eviden

128 Knowledge of noise covariations did not lead to better decoding performance

129 Our study indicates that spatial climate covariation drives the global carbon cycle response.

130 on due to RNA structure and removes spurious covariation due to phylogeny.

131 First, it uses significant covariation due to RNA structure and removes spurious co

132 hundred proteins sharing complex patterns of covariation (e.g. the lab-derived avGFP lineage).

133 However, others postulate that noise covariation effects may depend on network anisotropy/hom

134 Evolutionary rate covariation (ERC) is a phylogenetic signature that refle

135 Such evolutionary rate covariation (ERC) is a sequence-based signature of coevo

136 ruct gene networks via the evolutionary rate covariation (ERC) signature.

137 gnal transmission, we used Evolutionary Rate Covariation (ERC), a recently developed bioinformatic to

138 protein structure has constrained amino acid covariation for 40 diverse protein domains.

139 Statistical covariation for the shear stress stimulus did not alter

140 These covariations form a network with biological properties,

141 hat can be employed to determine patterns of covariation from both uni- and multivariate phenotypic c

142 ogram for statistical prediction of pairwise covariation from sequence alignments, but it initially s

143 ses in Australia's energy mix, this negative covariation has implications for storage capacity of exc

144 V-Phaser uses covariation (i.e. phasing) between observed variants to

145 Analyses of phenotypic and genetic covariation identified substantial correlations among th

146 Sequence covariation implies wide conservation of structural and

147 s--unexpected floods and droughts--determine covariation in abundance of native and non-native fish s

148 nificant similarities between the amino acid covariation in alignments of natural protein sequences a

149 Moreover, we identified covariation in amino acid transport and cofactor synthes

150 Here we test a developmental model of limb covariation in anthropoid primates and demonstrate that

151 ching geometries govern much of the observed covariation in biological scaling exponents.

152 sult in comparable variation and patterns of covariation in both species.

153 demographic variates, recently associated to covariation in brain function, can already be identified

154 a meta-analysis to characterize patterns of covariation in CCDs and identified functional or biosynt

155 study evaluates patterns of brain anatomical covariation in chimpanzees and humans to infer their inf

156 pread across the entire brain, and driven by covariation in cortical area, i.e. likely differences in

157 dies publish raw data to allow evaluation of covariation in cross-study syntheses, and we recommend a

158 erve that invasive cancers exhibit increased covariation in DNA methylation at the risk CpG sites rel

159 Importantly, we show that the covariation in DNA methylation at these risk CpG loci is

160 nd environmental influences on variation and covariation in EUE and EOE were established using a biva

161 ificity of GABAergic gene groups, defined by covariation in expression, for response to chronic alcoh

162 environment on the degree of diet-microbiome covariation in free-ranging African megafauna, and this

163 no acid residues are in contact by analysing covariation in homologous sequences, which aids in the p

164 The lack of covariation in humans may suggest a disconnect in climat

165 d climate in humans, contrasting with strong covariation in macaques.

166 sed morphometry (SBM) to examine gray matter covariation in magnetic resonance imaging scans and dete

167 validated technique based on across-subject covariation in magnetic resonance imaging-derived cortic

168 nents (PCs) of the G-matrix corresponding to covariation in metals response, nitrogen availability, o

169 Brain structural covariance networks reflect covariation in morphology of different brain areas and a

170 odel to simultaneously examine variation and covariation in multiple binary indicators across hospita

171 Results show a distinct pattern of shape covariation in Neanderthals, consistent with more extend

172 ements and ZF genes and was not explained by covariation in other genomic features.

173 ximum entropy approach to infer evolutionary covariation in pairs of sequence positions within a prot

174 ummary, we report structural brain-behaviour covariation in Parkinson's disease with distinct reward

175 We show that amino acid covariation in proteins, extracted from the evolutionary

176 or application by using them to help explain covariation in slopes of spatial and temporal TL (two co

177 vations from across Britain), we compare the covariation in temperature and first spawning dates of t

178 Molecular profiling therefore reveals covariation in the properties of thalamic pathways servi

179 del environmental filtering by variation and covariation in the responses of individual species to th

180 , His/Val, and Leu/Ile) that showed striking covariation in their concentrations across ST samples.

181 The resulting covariation in these rates determines population dynamic

182 traits indicate that a small portion of the covariation in these traits can be explained by the repo

183 By linking estimated covariation in tree growth and mortality over time with

184 rvation of RNA base pairing induces pairwise covariations in sequence alignments.

185 Do slow trial-by-trial noise covariations increase or decrease IT's object coding cap

186 SHAPE probing structural data and nucleotide covariation information from structure-based alignments.

187 of thermodynamic stability and evolutionary covariation information.

188 ing algorithms that incorporate all positive covariation into one structure.

189 Although covariation is not direct evidence of structural propens

190 Particularly, increased covariation is observed between subsets of characters fr

191 Consistent with the proposal that muscle covariation is related to similarity of muscle actions o

192 the similarity between natural and designed covariation is sensitive to the magnitude and mechanism

193 Our results suggest that negative covariation is widely anticipated from theory.

194 By contrast, we identified a strong mode of covariation linking functional network connectivity to c

195 nal structure, the improved understanding of covariation may help identify functional residues involv

196 While covariation methods have effectively and accurately pred

197 The inapplicability of amino acid covariation methods to small protein families has limite

198 Alternatively, this covariation might reflect regulation of low-level aspect

199 Covariation network analysis using the fetal neocortex d

200 ork independent of the V3 loop; and (iv) the covariation network formed between the V3 loop and other

201 iii) CD4 binding sites form part of a unique covariation network independent of the V3 loop; and (iv)

202 nce and found that (i) there are complicated covariation networks, indicating frequent coevolutionary

203 e results suggest that networks of intrinsic covariation observed at multiple levels and with several

204 dies have demonstrated that such patterns of covariation occur, although these are often between samp

205 arations that permit measurement of both the covariation of a neuron's input signals and the effect o

206 s a phylogenetic signature that reflects the covariation of a pair of proteins over evolutionary time

207 statistical modeling of the population level covariation of alleles across the chromosome and model-f

208 s demonstrate that the observed compensatory covariation of amino acids in eukaryotic loop 2 is essen

209 ural insights from an unexpected source: the covariation of amino acids in sequences of different cur

210 from the right hemisphere with only moderate covariation of amplitude, and drive CA1 pyramidal units

211 Decomposing variance revealed that covariation of bacterial clades within human body sites

212 ctions may lead to either co-conservation or covariation of binding interfaces.

213 Intrinsic covariation of brain activity has been studied across ma

214 The covariation of carbon dioxide (CO(2)) concentration and

215 This effect results from per-nucleus covariation of chromosome axis lengths.

216 Factor analysis was used to assess spatial covariation of condition prevalence and to construct a c

217 then used this decomposition to explain why covariation of correlations with firing rate-a relations

218 The covariation of dissolved nitrate and phosphate is mainta

219 (COCOA), a computational framework that uses covariation of epigenetic signals across individuals and

220 Thus, covariation of excitatory and inhibitory inputs can be a

221 We analyze covariation of fungal and bacterial taxa, and find that

222 gray matter networks (GMNs) emerge from the covariation of gray matter volume and cortical area at t

223 ful structural architecture emerges from the covariation of gray matter volume and cortical folding.

224 orks derived from analysis of inter-regional covariation of gray matter volume in MRI data on 259 hea

225 ore, we developed a predictive model for the covariation of H, D, and stem volume V scaling relations

226 ssibility that the visual system may use the covariation of local surface orientation and intensity a

227 Thus, the ubiquity in mammals of the covariation of longer cortical neurogenesis and increase

228 ance of enzyme and substrate concentrations, covariation of magnesium and nucleoside triphosphates, a

229 l framework for understanding the origin and covariation of many allometric traits within a complex i

230 trolled and field conditions and examine the covariation of mesophyll conductance with photosynthetic

231 up, sparse partial least squares analysis of covariation of microbial, inflammatory, and clinical par

232 We examined the covariation of mind perception with three subclinical sy

233 Despite these selection pressures, genetic covariation of morphology, phenology and lifespan appear

234 To examine covariation of mutations between two different sites usi

235 We examined covariation of pathogen infection and bacterial microbio

236 fied 11 pleiotropic hQTLs that determine the covariation of shoot and taproot growth.

237 Because the covariation of symptoms of functional disorders cannot b

238 Here we introduce a method to measure covariation of the excitatory and inhibitory inputs a ce

239 on methods; heritability of brain variation; covariation of the sizes of brain regions; and correlati

240 oxygen perturbations-precisely mirroring the covariation of these parameters upon transitions between

241 Extensive QTL co-localization suggests that covariation of these traits is likely due to pleiotropy,

242 is analysis expands our understanding of the covariation of UV-B irradiance and UV floral pigmentatio

243 We propose that the covariation of voltage dependences of ion channels repre

244 ng that limitation in mind, it is shown that covariations of cloud and environmental properties in th

245 Here, we examined trial-to-trial covariations of concurrently recorded EEG and fMRI in a

246 results suggest that changes in gm depend on covariations of multiple leaf (S(mes)) and M cell (inclu

247 how the study of changes in DNA methylation covariation patterns across normal, intra-epithelial neo

248 S) method, processed to systematically infer covariation patterns among biochemically related metabol

249 Mfold and phylogenetic covariation patterns among similarly grouped betacoronav

250 th the removal of Arctic populations turning covariation patterns compatible with evolution by geneti

251 cts on the default-mode network by examining covariation patterns in functional connectivity among 33

252 We examined these issues by analyzing covariation patterns in quadriceps muscle activity durin

253 ides a general tool to identify evolutionary covariation patterns in small sets of close sequence hom

254 nds revealed biosynthetic constraints in the covariation patterns of plant CCDs.

255 We expect computation of covariation patterns to complement experimental structur

256 both performance and evolutionary signals on covariation patterns.

257 important in the maintenance of established covariation patterns.

258 It has been shown that natural variation and covariation provide valuable insights into the developme

259 or neurons with correlated tuning, and noise covariations reduced object encoding capability, includi

260 According to one common proposal, this covariation reflects simplification of task performance

261 etwork anisotropy/homogeneity and on how the covariation relates to representation.

262 atory analyses of interregional resting rCBF covariation revealed a specific and significant diagnosi

263 These results (1) support a totally new covariation scaling model, (2) indicate that differences

264 ibe a method for distinguishing when lack of covariation signal can be taken as evidence against a co

265 ctions are often inaccurate because the true covariation signal in the MSA is often masked by biases

266 ines three distinct approaches for inferring covariation signals from multiple sequence alignments, c

267 oncluded that an unmeasured trait drives LES covariation, sparking efforts to identify the latent phy

268 tions within the same RNA molecule, enabling covariation studies.

269 er, and model simulations confirmed that the covariation suffices to normalize the somatic AP wavefor

270 tegrated than those of plants (i.e. stronger covariation), suggesting that animals communicate via fi

271 ong non-coding RNAs previously shown to lack covariation support do have adequate covariation detecti

272 bsets of neurons may be more immune to noise covariation than others.

273 bsets of neurons may be more immune to noise covariation than others.

274 ng free from the constraints associated with covariation that have been observed between certain kine

275 activity at the same sites exhibited spatial covariation that reflected the tonotopic map of the STP.

276 t the full extent of macroecological pattern covariations, the role of the constraints imposed by fin

277 Of the PE that showed covariation, this appeared to be due to shared genetic i

278 cess of using natural, evolutionary sequence covariation to compute protein and RNA folds, we explore

279 ltaneously and examined their trial-to-trial covariations to gain insight into these attentional cont

280 models that account for seasonal demographic covariation using a latent variable.

281 Unexpectedly, amino acid covariation was highest between VP4 and VP2, which are s

282 ison analysis suggested that this structural covariation was sufficient to account for the behavioral

283 Covariations were predominantly positive (> 80%), sugges

284 ally distinct lines of mice, finding minimal covariation when comparing synaptically connected or dev

285 Amino acid covariation, where the identities of amino acids at diff

286 nd transdiagnostic mode of genome-connectome covariation which is positively and specifically correla

287 res revealed three population modes of brain covariation, which were robust as assessed by cross-vali

288 N:P and stem diameter (D) showed significant covariations, which indicates that leaf N and W, N:P and

289 would be particularly likely to show genetic covariation with ADHD.

290 f abundance can be explained entirely by its covariation with geographic range.

291 through metabolomic 'guilt by association' (covariation with known metabolites).

292 Fecal microbiota showed covariation with mucosal adherent microbiota.

293 ubregions of the dorsal cingulate cortex and covariation with rated pain.

294 ting method (PEC) for quantifying positional covariation with the Gutell lab's new RNA Comparative An

295 Second, we report a significant covariation with the level of AED load and a wake-depend

296 may affect hearing capacity or could reflect covariation with the surrounding temporal bone.

297 on between VM and VL was stronger than their covariations with RF.

298 tween VM and VL was also stronger than their covariations with VI.

299 cterize natural polymorphisms and amino acid covariation within an inhibitor-naive sequence set spann

300 Jaccard index was used to analyze amino acid covariation within HIV-1 integrase.