コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 n for shared human CDR3betas that are highly cross-reactive.
2 ide binding, the ILA1 T-cell clone was still cross-reactive.
3 nigmatic: TCRs are at once specific but also cross-reactive.
4 bor intensive, and the resulting TCRs may be cross-reactive.
5 CMV epitopes, either conserved, variant, or cross-reactive.
6 a human anti-CD3 specificity that is rhesus cross-reactive.
7 at NA immunity can be protective and broadly cross-reactive.
9 associated with more-severe disease, and no cross-reactive Abs against prior betacoronavirus were fo
10 results suggest that DENV NS1 can induce Plg cross-reactive Abs through molecular mimicry, which can
15 ing the pIP501 plasmid and also proved to be cross-reactive against other clinically relevant enteroc
16 ve long been diagnosed with serum antibodies cross-reactive against Proteus vulgaris (Weil-Felix reac
18 small number of amino acid differences among cross-reactive allergens can reduce the affinity of bind
19 ed to be termed 'fish-chicken syndrome' with cross-reactive allergens involved being parvalbumins, en
21 at commercial Cpn and Ctr ELISA antigens are cross-reactive among all Chlamydia spp., but Cpn and Ctr
23 tive Ags (COBRA) targeting H1 elicit a broad cross-reactive and cross-neutralizing Ab response agains
24 otential of the human immune system to mount cross-reactive and cross-protective humoral immune respo
25 of heterogeneous and functionally competent cross-reactive and induced memory CD8(+) T cell response
29 sing features of IgA, being at the same time cross-reactive and selective in its interactions with th
30 les to estimate the contribution of serotype-cross-reactive and type-specific antibodies to neutraliz
31 lated flaviviruses has long been known to be cross-reactive, and antibody detection of ZIKV is nonspe
32 conclusion, TXB2 is a high affinity, species cross-reactive, and brain-selective VNAR antibody to TfR
34 llenge in dengue vaccine development is that cross-reactive anti-DENV Abs can be protective or potent
35 raries demonstrated that biopannng against a cross-reactive anti-Luk monoclonal antibody (MAb) recove
36 etermine whether the specificities of a less cross-reactive anti-Zaire ebolavirus sdAb and a totally
38 into dengue virus (DENV) endemic regions and cross-reactive antibodies (Abs) could potentially affect
39 er was based on a virus that elicits broadly cross-reactive antibodies against a wide range of H5 vir
40 1 glycoconjugate resulted in high titers of cross-reactive antibodies against CR-Kp CPS in mice and
41 nd ability of the vaccines to elicit broadly cross-reactive antibodies against the hemagglutinin stal
42 etting the concern of ZIKV vaccines inducing cross-reactive antibodies and sensitizing people to subs
43 duced the exposure of epitopes recognized by cross-reactive antibodies and therefore showed a lower p
44 Ad5 vaccine induced dominant gp41-microbiota cross-reactive antibodies derived from blood memory B ce
46 envelope proteins raise the possibility that cross-reactive antibodies induced following Zika virus i
47 ines as the induction of poorly neutralizing cross-reactive antibodies may prime an individual for AD
48 o influenza and suggests that once elicited, cross-reactive antibodies targeting the HA stem can pers
49 a virus vaccine candidates to induce broadly cross-reactive antibodies targeting the stalk domain of
50 d to identify conserved HA epitope selecting cross-reactive antibodies that mediate heterosubtypic pr
52 isk, we evaluated the levels of heterologous cross-reactive antibodies to A(H3N2)v cluster 2010.1 vir
53 isk, we evaluated the levels of heterologous cross-reactive antibodies to A(H3N2)v cluster 2010.1 vir
54 fluenza vaccine would need to elicit broadly cross-reactive antibodies to multiple H2 influenza virus
55 al survey using a novel approach to rule out cross-reactive antibodies to other seasonal influenza vi
56 d sGP in complex with GP-specific and GP/sGP cross-reactive antibodies undergoing human clinical tria
58 pe on envelope (E) protein-are recognized by cross-reactive antibodies(1-3) that are not only poorly
61 might continue to circulate, and to generate cross-reactive antibodies, particularly towards conserve
67 Guinea pigs developed high titers of broadly cross-reactive antibodies; mice and ferrets exhibited na
68 immunoassay-like setting by capturing with a cross-reactive antibody (R109) binding to both proteins
69 Here, we examine the structural basis for cross-reactive antibody binding to RSV and HMPV F protei
70 differences in the degree of homologous and cross-reactive antibody boosting elicited by different e
72 a on weight loss, viral replication, and the cross-reactive antibody response, we identified A/mallar
73 ble infection; however, we could not exclude cross-reactive antibody responses to seasonal influenza
74 Anhui/1/2005 (clade 2.3.4) vaccine to elicit cross-reactive antibody responses to these emerging viru
75 c germinal centers give rise to more broadly cross-reactive antibody responses, thereby generating cr
78 Unexpectedly, Pca1 immunization generated cross-reactive antibody that recognized Pneumocystis jir
79 predicts the presence of SARS-CoV/SARS-CoV-2 cross-reactive antibody titers specific for the receptor
81 h both an sGP-specific antibody and a GP/sGP cross-reactive antibody, permits us to unambiguously ass
82 nactivated A(H7N9) vaccines elicited robust, cross-reactive antibody-dependent cell-mediated cytotoxi
83 current study we examined type-specific and cross-reactive antibody-dependent cellular cytotoxicity
85 tis surface protein, designated Pneumocystis cross-reactive antigen 1 (Pca1), as a potential vaccine
86 l prophage in stools and expression of a TMP-cross-reactive antigen by tumors correlated with long-te
87 tients were more likely to seroconvert for a cross-reactive antigen if they seroconverted for the spe
88 be taken into account when designing broadly cross-reactive antivirals against NoVs.IMPORTANCE Human
90 the phenotype of DENV serotype-specific and cross-reactive B cells during and after natural DENV inf
94 R-HPVs, including finding 3 broadly antibody cross-reactive BCEs of L1 that each covers almost all HR
95 mmunodominant CD8 T cell response apparently cross-reactive between a newly defined putative MCMV epi
97 lidated immunogenic B-cell epitopes that are cross-reactive between members of the pore-forming leuko
98 from the receptor binding site, that enables cross-reactive binding between SARS-CoV-2 and SARS-CoV.
99 ils parallel selection to selectively enrich cross-reactive binding sequences, followed by serial sel
101 ls of 50 and 100 Envs either to characterize cross-reactive breadth for sera identified as having pot
102 sort for cells that are recognized by trimer cross-reactive broadly neutralizing antibody (bnAb) and
109 As IgE glyco-epitopes, also referred to as cross-reactive carbohydrate determinants (CCDs), can sha
112 two distinct intact IgE with specificity for cross-reactive carbohydrate determinants and Der p 2 as
113 ur immunological scenarios for the impact of cross-reactive CD4(+) memory T cells on COVID-19 severit
114 epeated annual influenza vaccination on both cross-reactive CD4+ and CD8+ T cells has not been explor
118 without compromising the induction of robust cross-reactive CD8+ T cell responses upon exposure to vi
119 plicating a preferential selection of shared cross-reactive CDR3betas during repertoire formation.
120 sponsive animals support a critical role for cross-reactive central memory T cells in viremia control
122 ay even favor the expansion and dominance of cross-reactive clones, but only when conflicting selecti
124 ith cockroach allergen, we observed that non-cross-reactive epitope predominantly determined IgE bind
126 results identify ZIKV-specific and ZIKV/DENV cross-reactive epitopes and demonstrate both an altered
127 vaccinations for related pathogens and that cross-reactive epitopes and TCRs may be useful for multi
129 ion of mice with ZIKV-specific and ZIKV/DENV cross-reactive epitopes elicited CD8(+) T cell responses
131 the engineered immunogens should have their cross-reactive epitopes masked, and they should be optim
135 ied the DENV NS1 by replacing the C-terminal cross-reactive epitopes with the corresponding region of
141 neutralizing antibody specificities that are cross-reactive for VACV, CPXV, MPXV, and VARV and that a
143 trates for CB6 click that do not contain any cross-reactive functional groups and by optimizing react
145 PV and 38.37% (95% CI = 12.68-56.51) against cross-reactive genotypes (HPV 31, 33, 45), respectively.
147 imothy grass pollen allergen, belongs to the cross-reactive group 1 grass pollen allergens that are t
149 ogous prime-boost vaccination induced modest cross-reactive HI antibody responses to H5Nx viruses.
150 hat breaching peripheral tolerance permits a cross-reactive HIV-1 autoantibody response able to neutr
151 +) T cells from DENV-infected mice, and five cross-reactive HLA-B*0702-binding peptides were identifi
152 n this study, we discover and characterize a cross-reactive human IgA monoclonal antibody, MAb362.
153 SA inhibition results showing that, although cross-reactive human IgE epitopes exist, there are uniqu
154 n children may offer some protection, due to cross-reactive humoral immunity and T cell immunity betw
156 f mold allergy, and determination of a major cross-reactive IgE-epitope has clinical potential for th
158 t v 1 SLIT induced Bet v 1-specific, Mal d 1-cross-reactive IgG antibodies with limited cross-blockin
159 munization of mice and rabbits, MBC4 induced cross-reactive IgG antibodies, which were able to block
160 n by LJM17 from L. longipalpis-elicited DSG1-cross-reactive IgG4 antibodies may lead to FS in genetic
161 cal aspects and implications of pre-existing cross-reactive immune memory to SARS-CoV-2, which largel
162 ine may have the added benefit of inducing a cross-reactive immune response to viral strains not foun
163 sess the magnitude and functional quality of cross-reactive immune responses between these closely re
166 se data demonstrate that M type-specific and cross-reactive immune responses occur following skin inf
167 phoidal serovar, Salmonella Typhi, generates cross-reactive immune responses, which provide far great
168 commercial CIV H3N8 IIV but provided limited cross-reactive immunity and heterologous protection agai
169 ld-type C57BL/6 mice infected with ZIKV have cross-reactive immunity to subsequent ZIKV infection and
171 as been a challenge given preexisting, often cross-reactive, immunity and in particular, poorly immun
173 nto chickens, the HN13-derived antiserum was cross-reactive in immunoblots with all tested 32 field i
174 n, gut-derived IgA monoclonal antibodies are cross-reactive in the sense that they bind to multiple b
178 e neutralizing antibodies were detected, but cross-reactive interferon-gamma-secreting T cells were d
183 dy therapy for NiV and HeV using a humanized cross-reactive mAb targeting the F glycoprotein, and the
184 e a structural and molecular mechanism for a cross-reactive mAb that uniquely neutralizes ZIKV and DE
186 d that the RV-A15-specific mAbs, but not the cross-reactive mAbs, had neutralizing activity against R
188 ; the H. influenzae protein D (HiD); and the cross-reactive material from diphtheria toxin (CRM197).
189 covery of infused BeneFix (FIX(WT)) in null (cross-reactive material negative, CRM(-)) hemophilia B m
190 engue virus elicits robust type-specific and cross-reactive MBC responses after primary and secondary
192 fections does not influence type-specific or cross-reactive MBC responses, although ZIKV has the high
194 requency and proportion of type-specific and cross-reactive MBCs were comparable between primary and
195 both high-quality neoantigens and predicted cross-reactive microbial epitopes, consistent with neoan
196 antibodies, specifically the two identified cross-reactive monoclonal antibodies (KL-2E5 and KL-2H7)
199 d to characterize the potency and breadth of cross-reactive neutralization by monoclonal antibodies,
201 esponse comprising very potent and extremely cross-reactive neutralizing antibodies [broadly neutrali
202 three viral challenges and produced broadly cross-reactive neutralizing antibodies to H2 influenza v
207 nd characterized a panel of vaccine-elicited cross-reactive neutralizing MAbs targeting the Env V3 lo
208 al studies demonstrated that the most potent cross-reactive neutralizing mAbs, HENV-26 and HENV-32, p
210 ion in ferrets and non-human primates with a cross-reactive, neutralizing human monoclonal antibody (
211 anced in the presence of sub-neutralizing or cross-reactive non-neutralizing antiviral antibodies.
212 we report the characterization of 22 broadly cross-reactive, nonneutralizing antibodies specific for
213 se might be diverted from one site to a more cross-reactive one, which would help in the induction of
219 the related dengue virus is the induction of cross-reactive poorly neutralizing antibodies that can c
220 seasonally circulating coronaviruses induce cross-reactive, potentially even cross-neutralizing, ant
221 recognized by virus-specific and flavivirus cross-reactive potently neutralizing antibodies that hav
224 avian influenza (H5N1) virus elicits robust, cross-reactive protection from influenza virus infection
226 ng capsule-based vaccination with conserved, cross-reactive protein-based vaccines broadens and enhan
228 led three structural epitopes: two partially cross-reactive regions around alpha-helices 2 and 4 as w
229 m MCMV-immune mice mount a robust CD8 T cell cross-reactive response between a newly defined putative
232 ry and secondary DENV infections, within the cross-reactive response, the breadth of MBC responses ag
234 f fHbp in N. cinerea and N. meningitidis and cross-reactive responses elicited by Bexsero suggest tha
235 e protein have been hampered by concerns for cross-reactive responses that induce antibody-dependent
236 iple flaviviruses; however, the magnitude of cross-reactive responses was consistently severalfold lo
237 Moreover, in the uncommon instances where cross-reactive responses were detected, the variant epit
240 stitute a potential new source of primary or cross-reactive sensitization to lupin, particularly to L
241 , the single sensor device integrated in the cross-reactive sensor matrix exhibits multimodal detecti
244 al influenza virus vaccine regimens elicited cross-reactive serum IgG antibodies that targeted the co
245 ody (2.2-5.6 times induction over baseline), cross-reactive serum IgG antibody, and peripheral blood
246 ka virus infection induced detectable Dengue cross-reactive serum IgG responses that significantly am
248 A vaccine providing both powerful Ab and cross-reactive T cell immune responses against influenza
249 sum, we argue that key potential impacts of cross-reactive T cell memory are already incorporated in
250 nexposed individuals, suggesting preexisting cross-reactive T cell memory in 20 to 50% of people.
251 uction of two completely independent and non-cross-reactive T cell populations that show distinct fun
252 40%-60% of unexposed individuals, suggesting cross-reactive T cell recognition between circulating "c
253 This results indicate that spike-protein cross-reactive T cells are present, which were probably
254 In the absence of neutralizing antibodies, cross-reactive T cells have been shown to limit disease
256 oof of concept that LAIVs boost preexisting, cross-reactive T cells in children to genetically divers
258 unity to related flaviviruses could generate cross-reactive T cells that may affect immune responses
260 he use of LAIV in children to elicit broadly cross-reactive T cells, which are not induced by traditi
264 cord with the observations that pre-existing cross-reactive T-cells correlate with protection in huma
265 f a soy-peptide-containing an immunodominant cross-reactive T-epitope, along with a single B epitope,
266 A) protein can be protective and are broadly cross-reactive, the immune response to NA during infecti
267 ) responses, as well as weak and/or sporadic cross-reactive tier 2 virus NAb responses with unknown s
268 elineate the specificity of vaccine-elicited cross-reactive tier 2 virus NAb responses, we performed
269 3-specific MAbs, nearly 20% (6/33) displayed cross-reactive tier 2 virus neutralization, which recapi
271 uster IV A(H3N2)v vaccine induced antibodies cross-reactive to cluster 2010.1 viruses in about 1/3 of
272 uster IV A(H3N2)v vaccine induced antibodies cross-reactive to cluster 2010.1 viruses in approximatel
277 golipids and phospholipids, but were broadly cross-reactive towards diverse phospholipids including p
278 itope, and our attempts to rationally design cross-reactive trimers resulted in only limited success.
279 ology were observed between selected macaque cross-reactive V3 NAbs elicited by vaccination and proto
281 H and SARS-CoV-2 S and demonstrate that this cross-reactive VHH neutralizes SARS-CoV-2 S pseudotyped
284 R was identified as a high affinity, species cross-reactive VNAR antibody against TfR1-ECD that does
285 es and found that the synbodies were broadly cross-reactive with affinities that ranged from 0.5 to 8
287 ria/2/1987-like lineage, and two were highly cross-reactive with B/Yamagata/16/1988-like lineage viru
288 at systemic and lung mucosal immunoglobulins cross-reactive with beta-glucan and chitosan/chitin are
289 Notably, lung mucosal quantities of IgA cross-reactive with beta-glucan or chitosan/chitin are d
290 l depletion did not impact quantities of IgG cross-reactive with beta-glucan or chitosan/chitin in th
291 ls was low and dominated by clones that were cross-reactive with both Ebola glycoprotein (GP) and wit
292 f preexisting memory CD4(+) T cells that are cross-reactive with comparable affinity to SARS-CoV-2 an
294 DENV nonstructural protein 1 (NS1) which are cross-reactive with host Ags and trigger anti-DENV NS1 A
295 naturally processed cancer antigens that are cross-reactive with microbial peptides were detected.
296 FM15-35 Although NFM15-35 is immunogenic and cross-reactive with MOG at the polyclonal level, it fail
297 g the acute phase of infection and are often cross-reactive with similar pathogenic and nonpathogenic
299 gp41 membrane proximal region (MPER) and is cross-reactive with the HIV broadly neutralizing Ab (bnA
300 e whether an anti-Ebola virus sdAb, that was cross-reactive within the Ebolavirus genus, recognized a