ライフサイエンスコーパス: cryptand

1 pylcyclopentadienyl) as the salt of [K(2.2.2-cryptand)](+).

2 2) {mu-eta(2) (OP):eta(2) (CP)-OCP}][K(2,2,2-cryptand)].

3 capsulation of a Cs(+) counterion with 2.2.2-cryptand.

4 bonds to N-H groups from the hexacarboxamide cryptand.

5 onium complexes of self-assembled orthoester cryptands.

6 ulated F(-) complexes of the two amide-based cryptands.

7 but 1 and 2 were especially effective, where cryptand 1 was the most active, particularly in the chro

8 plex [K(crypt)][Tb(NR(2))(3)] (crypt = 2.2.2-cryptand), 1-Tb, reacts with dinitrogen in Et(2)O at -35

9 2.2-cryptand)][Cp(3)Th(CCCPh(2))] ([Li(2.2.2-cryptand)][1]), respectively.

10 Cryptand 12 exhibits the highest association constant fo

11 crown ether diol 1d was converted to pyridyl cryptand 12 in 44% yield by reaction with pyridine-2,6-d

12 The binding constant of diquat 4 by cryptand 12 is nearly 6-times higher than any other repo

13 (RO)(3)Li(2-), which were also observed when cryptand [2.1.1] was used as a cosolvent, or when mixed

14 cosolvent additives PMDTA, TMTAN, HMPA, and cryptand [2.1.1].

15 2)Ar)(3)-arene)](infinity) (3) and [(K(2.2.2-cryptand))](2)[U((OSi(O(t)Bu)(2)Ar)(3)-arene)] (3-crypt)

16 tion of [Co(I)2(bis-(OMe)salophen)Na2Py4][Na(cryptand)]2, 8.

17 lophen ligand, [Co((OMe)salophen-CO2)Na]2[Na(cryptand)]2, 9, was isolated but CO3(2-) formation in 53

18 pyrrolidinyl) and [Pu(3+)(NPC)(4)][K(2.2.2.-cryptand)], 2-Pu, is described.

19 in acetonitrile containing a large excess of cryptand[2.2.2] exhibits a Hush-type intervalence charge

20 directed synthesis of a per-aza analogue of cryptand[2.2.2] in which each of the linking arms contai

21 Ti(II) salt [K(cryptand)][(PN)(2)TiCl] (1) (cryptand = 222-Kryptofix) and Na(OCAs)(dioxane)(1.5) in

22 udorotaxane complex of the new hydroxymethyl cryptand 3 with N,N'-dimethyl-4,4'-bipyridinium bis(hexa

23 rm para to the ester linkages, "short-armed" cryptand 3, did display a higher binding constant (Ka =

24 diols 7 and 10 to the corresponding pyridyl cryptands 3 and 4 by reaction with pyridine-2,6-dicarbon

25 ding the complex [(Co((OMe)salophen))2Na][Na(cryptand)]3, 7.

26 op of red crystals determined to be [K(2.2.2-cryptand)](3)[{Th(Tren(TIPS))(mu-eta(3):eta(3)-Sb(3))}(2

27 arm para to the ester linkages, "long-armed" cryptand 4, possessed diminished binding with both paraq

28 ,10,13,16-hexaoxacyclooctadecane (18-C-6) or cryptand 4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8

29 Cryptands 4 and 5 were synthesized from cis- and trans-b

30 in a controllable manner on the basis of the cryptands' abilities to complex KPF6 strongly, providing

31 capsulation of K(+) in 2 with crown-ether or cryptand affords the first discrete salt [K(encap)][(PN)

32 [2.2.2]cryptand affords what is believed to be a contact-ion-pa

33 the supporting ligands 18-crown-6 and [2.2.2]cryptand allows the selective formation of contact ion p

34 The cryptands also form complexes with ammonium hexafluoroph

35 this interaction has been reported between a cryptand and paraquat.

36 were performed for 19 distances between the cryptand and the chloride.

37 ence of macrocyclic polyether ligands: L(C) (cryptand) and L(E) (crown-ethers).

38 (tbs)L)Fe(3)(mu(3)-NPh)] (4) (C(222) = 2,2,2-cryptand), and the mixed-valent ((tbs)L)Fe(3)(mu(3)-NPh)

39 -1,10-diazabicyclo[8.8.8]hexacosane ([2.2.2] cryptand); and tris[2-(2-methoxyethoxy)ethyl]amine (TDA-

40 All of the cryptands appear to encapsulate F(-) in solution, where

41 resulted complex induces the release of the cryptand as a major E,E,E isomer, while other studied an

42 3Th with H2 in the presence of KC8 and 2.2.2-cryptand at -45 degrees C produced two monometallic hydr

43 ts of KC(8) in THF, in the presence of 2.2.2-cryptand, at -78 degrees C.

44 Various cryptands based on 1,3-dioxane decorated 1,3,5-trisubsti

45 For the first time it was found that in cryptand-based complexes, different stoichiometries are

46 with relatively weak binding abilities, the cryptand-based host-guest interactions have a high assoc

47 Formation of the paraquat/cryptand-based pseudorotaxanes can be switched off and o

48 Exploration of this 2.2.2-cryptand-based reaction with the remaining lanthanides f

49 It was found that these cryptands bind paraquat derivatives very strongly.

50 of 3a and the previously reported homologous cryptand, bis(1,3,5-phenylene)tri(1,4,7,10,13-pentaoxatr

51 A new cryptand, bis(1,3,5-phenylene)tri(1,4,7,10-tetraoxadecyl

52 Crystal structures are reported for both cryptands, both paraquat diol-based pseudorotaxanes, bot

53 to be able to encapsulate the isomers of the cryptand by forming a Matryoshka-type complex.

54 nce of [2.2.2]cryptand to yield [Na(+)(2.2.2-cryptand)](C(137)H(121) (-)) (1) and [K(+)(2.2.2-cryptan

55 tand)](C(137)H(121) (-)) (1) and [K(+)(2.2.2-cryptand)](C(137)H(121) (-)) (2), respectively, is repor

56 ducts, namely, (C5Me4H)3ThH, 5, and [K(2.2.2-cryptand)]{(C5Me4H)2[eta(1):eta(5)-C5Me3H(CH2)]ThH]}, 6.

57 methylamino)ethyl]amine (Me(6)Tren) or 2,2,2-cryptand, can exert a level of reducing selectivity by p

58 The chloride can bind either inside the cryptand cavity or more loosely outside of the ligand.

59 e chloride into a stable position inside the cryptand cavity.

60 tary hydrogen bonds with the hexacarboxamide cryptand, [CO3 subsetmBDCA-5t-H6](2-) (2), a conclusion

61 on [Nd(II) (crypt)](2+) ], the first Nd(II) cryptand complex, assign a 4f(4) electron configuration

62 K+ displaces paraquat diol from the cryptands, converting yellow-orange solutions to colorle

63 ) (3(M)), respectively, as salts of [K(2.2.2-cryptand)](+) (Cp(Ge) = [GeC(4)-2,5-(SiMe(3))(2)-3,4-Me(

64 nt lanthanide complex salts, namely [K(2.2.2-cryptand)][Cp'3Ln] (Ln = Y, La, Ce, Pr, Nd, Sm, Eu, Gd,

65 These Ln(2+) complexes, [K(2.2.2-cryptand)][Cp'3Ln] (Ln = Y, Pr, Gd, Tb, Ho, Er, Lu), all

66 s, Cp'3Ln, 1, (Cp' = C5H4SiMe3) and [K(2.2.2-cryptand)][Cp'3Ln], 2, respectively, have been synthesiz

67 Y(2+), Ho(2+), and Er(2+) analogs: [K(2.2.2-cryptand)][Cp'3Ln].

68 .2.2-cryptand generates crystalline [K(2.2.2-cryptand)][Cp'3U], the first isolable molecular U(2+) co

69 hat this was not the U(3+) hydride, [K(2.2.2-cryptand)][Cp'3UH], which could be crystallographically

70 ))] ([Li(12-crown-4)(THF)][1]) and [Li(2.2.2-cryptand)][Cp(3)Th(CCCPh(2))] ([Li(2.2.2-cryptand)][1]),

71 of Sc(NR2 )3 with K in the presence of 2.2.2-cryptand (crypt) and 18-crown-6 (18-c-6) and with Cs in

72 2)Sc(II) with KC(8) in the presence of 2.2.2-cryptand (crypt) generates [K(crypt)][Cp(ttt)(2)Sc(III)(

73 ) in the presence of one equivalent of 2.2.2-cryptand (crypt) generates an intensely colored red-brow

74 lphenyl)(mesityl)amide] with KC(8) and 2.2.2-cryptand (crypt) resulted in formation of [K(crypt)][(PN

75 for linear coordination of Hg2+, whereas the cryptand derivative favors Pb2+ because of its larger ca

76 referentially bind Hg2+, except for the cage cryptand derivative, which favors Pb2+.

77 g comparable to the most effective bis(tren) cryptands despite binding anions via only three NH group

78 Reaction of the [2.2.2] cryptand (DHS) linker with Pb(II) in acidic media gave r

79 Specifically, the diazoborane anion [K(2.2.2-cryptand)](+)Dmp(Mes)BN(2)(-) (3, Dmp = 2,6-dimesitylphe

80 can be obtained in gram quantities from the cryptand-driven disproportionation reaction of potassium

81 Here we report self-assembling trimetallic cryptands (e.g. [L(2)(Metal)(3)](6+) where Metal = Cu(2+

82 lly reversible reduction of oxygen (O(2)) to cryptand-encapsulated O(2)(2-).

83 erties of 12 new receptors from the unclosed cryptand family.

84 The new cryptands form pseudorotaxanes with the paraquat derivat

85 potassium graphite in the presence of 2.2.2-cryptand generates crystalline [K(2.2.2-cryptand)][Cp'3U

86 CH(2) NSiPr(i) (3) )(3) ) with KC(8) /2,2,2-cryptand gives [{U(Tren(TIPS) )}(2) {mu-eta(2) (OP):eta(

87 of polyether ligands including crown ethers, cryptands, glycols, glymes, and related polyether ligand

88 binding to Li(+) (Me(6)Tren) or K(+) (2,2,2-cryptand), hence pushing the electron to the other catio

89 o crown ethers, this protocol makes powerful cryptand hosts readily available in gram quantities in g

90 m Ni(CO)(2)(PPh(3))(2), K(4)Sn(9), and 2,2,2-cryptand in en/toluene solvent mixtures.

91 red from Pt(PPh(3))(4), K(4)Sn(9), and 2,2,2-cryptand in en/toluene solvent mixtures.

92 The cryptand in its hexaprotonated form shows considerable a

93 With 2.2.2-cryptand in place of 18-crown-6 in the Cp'3Ln/K reaction

94 Chloride movement toward the cryptand is accompanied by stepwise dehydration of the a

95 This readily accessible cryptand is one of the most powerful hosts reported for

96 luding, but not limited to, crown ethers and cryptands, is responsible for the very high binding cons

97 3 reacts with the cryptand Krypt211 to form [Li(Krypt211)][(OPO)PdMe(py')]

98 CO and isocyanides in the presence of DME or cryptand (Kryptofix222), to form rare, five-coordinate T

99 K(2.2.2-cryptand)][La(Cp')(3)] (1), [K(2.2.2-cryptand)][La(Cp")(3)] (2), and [K(2.2.2-cryptand)][La(C

100 studies on three La(II) complexes, [K(2.2.2-cryptand)][La(Cp')(3)] (1), [K(2.2.2-cryptand)][La(Cp")(

101 2.2-cryptand)][La(Cp")(3)] (2), and [K(2.2.2-cryptand)][La(Cp(tt))(3)] (3), which feature cyclopentad

102 rate Nd(III) and Sm(III) ions into the 2.2.2-cryptand ligand (crypt) to explore their reductive chemi

103 s residing on the bridging O-atom and on the cryptand ligand for the case of 2.

104 chloride-selective receptor in the form of a cryptand-like cage using only CH hydrogen bonding.

105 A new class of cryptand-like ionophore based on a bis calix[4]arene str

106 tein can template its assembly into a unique cryptand-like protein complex ((C81/C96)RIDC14) by guidi

107 The "masked" terminal Zn sulfide, [K(2.2.2-cryptand)][(Me) LZn(S)] (2) ((Me) L={(2,6-(i) Pr(2) C(6)

108 adily with PhCCH and N(2) O to form [K(2.2.2-cryptand)][(Me) LZn(SH)(CCPh)] (4) and [K(2.2.2-cryptand

109 ptand)][(Me) LZn(SH)(CCPh)] (4) and [K(2.2.2-cryptand)][(Me) LZn(SNNO)] (5), respectively, displaying

110 ryptand yielded the title complex [K([2.2.2]-cryptand)][[{(Me(3)Si)(2)NC(N(i)Pr)(2)}(2)Y](2)(mu-n(6):

111 The irradiation of a 10:1 CB[8]-cryptand mixture has led to a selective conversion of th

112 The system under study consisted of a cryptand molecule, chloride ion, and 319 water molecules

113 guest occupies parts of the cavities of two cryptand molecules.

114 d Cs(+), as well as the separated ion pair K(cryptand)(+)NB(-*)-both series of which are structurally

115 (PyTFSI)-templated syntheses of 2,6-pyridyl cryptands of cis(4,4')-dibenzo-30-crown-10 (3a), the p-b

116 asier NMR assignment of the structure of the cryptands on the other side.

117 Two novel bis(m-phenylene)-32-crown-10-based cryptands, one bearing covalent linkages and the other m

118 rown-6 binds the KPF6 and allows the colored cryptand-paraquat complex to reform.

119 Herein, we exploit the cryptand/paraquat host-guest recognition motifs as cross

120 2)-KNa(thf)(2)) (2) and the discrete salt [K(cryptand)][(PN)(2)Ti=As] (3) featuring a terminal Ti=As

121 lation involving the discrete Ti(II) salt [K(cryptand)][(PN)(2)TiCl] (1) (cryptand = 222-Kryptofix) a

122 than the analogous dibenzo-30-crown-10-based cryptand previously studied; however, the effect was onl

123 ) with one or two equivalents of KC(8)/2.2.2-cryptand produces [{(eta(5)-Cp(Ge))M(eta(5)-Cp(ttt))}(2)

124 -electron reduction of 1(M) with KC(8)/2.2.2-cryptand produces the mono-anionic complexes [{(eta(5)-C

125 plete encapsulation of the alkali metal with cryptand provides the terminally bound nitride as a disc

126 ate for plutonium, namely Pu(2+) in [K(2.2.2-cryptand)][Pu(II)Cp''3], Cp'' = C5H3(SiMe3)2.

127 N)3Sc]2[mu-eta(1):eta(1)-N2]} (crypt = 2.2.2-cryptand, R = SiMe3), has been isolated from the reducti

128 LDA, in the presence of 12-crown-4 or 2.2.2-cryptand, results in the formation of discrete cation/an

129 The [K(2,2,2-cryptand)](+) salt is very air and moisture sensitive an

130 The [K(2,2,2-cryptand)](+) salt is very air and moisture sensitive, i

131 de capture from water by the tetraprotonated cryptand SC24 is presented.

132 es showed that the pyridine-containing amide cryptand shows the highest affinity (K(a) > 10(5) in DMS

133 irradiation and without the assistance of a cryptand, such as K2.2.2, primary substrates with select

134 he previously reported Ni congener, [K(2.2.2-cryptand)][(tBu) LNi(S)] ((tBu) L={(2,6-(i) Pr(2) C(6) H

135 ld green Sb(2)(*3-) radical complex [K(2.2.2-cryptand)][{Th(Tren(TIPS))}(2)(mu-eta(2):eta(2)-Sb(2))]

136 KC(8) gives the mono(arene) complex [K[2.2.2]cryptand][Th(TDA)(3)(THF)] (5).

137 ne solvent mixtures in the presence of 2,2,2-cryptand to give four different complexes: "Rudolph's co

138 ure has led to a selective conversion of the cryptand to the E,E,Z isomer inside CB[8].

139 potassium graphite in the presence of 2.2.2-cryptand to the uranium(I) metallocene [U(eta(5)-C(5)(i)

140 th Na and K metals in the presence of [2.2.2]cryptand to yield [Na(+)(2.2.2-cryptand)](C(137)H(121) (

141 l pnictidenes [An(Tren(TCHS) )(PnH)][M(2,2,2-cryptand)] (Tren(TCHS) ={N(CH(2) CH(2) NSiCy(3) )(3) }(3

142 t)Bu)(2)Ar)(3)-arene)(THF)] (2) and [K(2.2.2-cryptand)][U((OSi(O(t)Bu)(2)Ar)(3)-arene)(THF)] (2-crypt

143 ene (CHT) to form the U(IV) complex [K[2.2.2]cryptand][U(n(7)-C(7)H(7))(TDA)(2)(THF)] (7).

144 elds the anionic bis(arene) complex [K[2.2.2]cryptand][U(TDA)(2)] (3) (TDA = N-(2,6-di-isopropylpheny

145 rates a mixture of the U(III) anion [K[2.2.2]cryptand][U(TDA)(4)] (1-crypt) and U(COT)(2), while the

146 ile late-stage functionalization of unclosed cryptands (UCs) (11 examples, yield up to 99%).

147 ear U(III)-U(III) triiodide species [K[2.2.2]cryptand][(UI(TDA)(2))(2)(u-I)] (6) and as a three-elect

148 ooperative change in the conformation of the cryptand when the Cl- starts to enter the ligand and jus

149 xes, [K(crypt)][Cp'(3)Ln(II)] (crypt = 2.2.2-cryptand), which have either 4f(n+1) (Sm, Eu) or 4f(n)5d

150 2-Tb), Dy (2-Dy), Y (2-Y); crypt-222 = 2.2.2-cryptand), which were obtained from one-electron reducti

151 Specifically, a diester cryptand with a pyridyl nitrogen atom located at a site

152 independent synthesis: treatment of (i) free cryptand with K2CO3; (ii) monodeprotonated cryptand with

153 e cryptand with K2CO3; (ii) monodeprotonated cryptand with PPN[HCO3]; and (iii) free cryptand with TB

154 ated cryptand with PPN[HCO3]; and (iii) free cryptand with TBA[OH] and atmospheric CO2.

155 Also as expected, the cryptand with the tetra(ethyleneoxy) arm para to the est

156 from Corey-Pauling-Koltun (CPK) models, the cryptand with the tri(ethyleneoxy) arm para to the ester

157 irradiation, stabilizing the isomers of the cryptand with Z-configurations.

158 Four new bis(m-phenylene)-32-crown-10-based cryptands with different third bridges were prepared.

159 of [K(crypt)][(PN)(2)TiCl] (1, crypt = 2.2.2-cryptand) with [Na(OCP)] results in [K(crypt)][(PN)(2)Ti

160 graphite (KC(8)) in the presence of [2.2.2]-cryptand yielded the title complex [K([2.2.2]-cryptand)]

161 KC(8) in the presence of 1.1 equiv of 2.2.2-cryptand yields the emerald green Sb(2)(*3-) radical com

162 )O at -35 degrees C in the presence of 2.2.2-cryptand, yields the green Sc(II) metallocene iodide com