ライフサイエンスコーパス: curcumin

1 mechanism of action for orally administered curcumin.

2 i-inflammatory efficacy compared to standard curcumin.

3 developed and used as delivery vehicles for curcumin.

4 s FOXP3 were upregulated in the colon by ETO-curcumin.

5 hen used as the wall material to encapsulate curcumin.

6 ncer cells and showed lower IC50 values than curcumin.

7 stases was associated with response to OXA + Curcumin.

8 -MOFs and the phenolic hydroxyl group of the curcumin.

9 butes to the anti-inflammatory properties of curcumin.

10 8, (-) epigallocatechin-3-gallate (EGCG), or curcumin.

11 y higher oxidative stability to encapsulated curcumin.

12 rmal and oxidative stability of encapsulated curcumin.

13 in by 173-fold when compared to the original curcumin.

14 oparticles to enhance the bioavailability of curcumin.

15 ing, we identified two distinct responses to curcumin.

16 one to denaturation and subsequently release curcumin.

17 The result shows that curcumin (46.8-59.50%) was major among all varieties, fo

18 he presence of +/-25 uM resveratrol, +/-1 uM curcumin, +/-5 mg/L theophylline, +/-1uM prednisolone an

19 ed significantly higher thermal stability to curcumin (91.8 +/- 1.0% and 99.7 +/- 3.1% at 70 degrees

20 parate cohort of mice was treated daily with curcumin, a clinically tested radioprotector, prior to a

21 and that SMSr oligomerization is promoted by curcumin, a drug known to perturb ER ceramide and calciu

22 JAK2 activity was inhibited using either curcumin, a natural compound with strong JAK2 inhibitor

23 Oral consumption of curcumin, a natural polyphenol, is associated with reduc

24 the exact targets and mechanism of action of curcumin, a natural product with anti-inflammatory and a

25 stance but was attenuated by the addition of Curcumin, a non-toxic NF-kappaB inhibitor.

26 has shown promise in the clinical setting is curcumin, a polyphenol compound found in the rhizome of

27 Chemopreventive efficacy of oral curcumin: a prodrug hypothesis.

28 Oxidative metabolites of curcumin adducted to and inhibited the inhibitor of NF-k

29 ohexanone (BM2) was 17 times more toxic than curcumin after 48 h incubation.

30 We find that curcumin allows fibril-like structures containing the sa

31 ior protection from DSS-induced colitis than curcumin alone, highlighting the anti-inflammatory poten

32 The color of the sample containing curcumin also became worse than its day-of-production st

33 Importantly, curcumin also prevented anxiety-like behavior in both re

34 STAT3 inhibition with micellar curcumin also suppressed postablation stimulation of dis

35 capacity of the liposomes was around 1.5% of curcumin, although the loading capacity of the hybrid mi

36 An unstable, alkynyl-tagged curcumin analog yielded abundant adducts with cellular p

37 Here, we characterize a novel curcumin analog, ASC-JM17, as an activator of central pa

38 Synthetic curcumin analogs that undergo oxidative transformation p

39 lity, solubility and antioxidant activity of curcumin and additionally are biocompatible.

40 Total phenolics, curcumin and antioxidant capacity were determined by spe

41 In fact, the initial interaction between curcumin and CD-MOF is crucial for the formation of the

42 The interaction between curcumin and CD-MOFs is strong through hydrogen bond typ

43 least 3 orders of magnitude compared to free curcumin and curcumin:gamma-CD at pH 11.5.

44 active metabolites, increased the potency of curcumin and decreased the amount of curcumin-glutathion

45 ion into NSAs decreased the crystallinity of curcumin and did not create any chemical bonding between

46 Selective M-MDSC chemoresistence to curcumin and DTX was mediated by secretory/cytoplasmic c

47 dings suggest that the combined treatment of curcumin and essential turmeric oils provides superior p

48 rostaglandin E2 (PGE2) show that, esculetin, curcumin and hesperetin were the principal constituents

49 the suitability of the approach to stabilize curcumin and increase its bioaccessibility was assessed.

50 curcumin dosing led to tumor accumulation of curcumin and inhibition of tumor growth in tumor models

51 Curcumin and its analogs have been identified as potenti

52 v/v of methanol content) on the stability of curcumin and its analogues demethoxycurcumin and bisdeme

53 Curcumin and its chalcone derivatives inhibit the growth

54 The precise mode of action of curcumin and its impact on system level protein networks

55 ively as other anti-aging compounds, such as curcumin and metformin.

56 evaluation and design of clinical trials of curcumin and other polyphenols of medicinal interest.

57 ity for two extremely water insoluble drugs, curcumin and paclitaxel.

58 reviews the essential medicinal chemistry of curcumin and provides evidence that curcumin is an unsta

59 sed of resveratrol, ellagic acid, genistein, curcumin and quercetin to modulate biomarkers indicative

60 anti-aggregation effects of two polyphenols, curcumin and resveratrol, on the aggregation of islet am

61 on of two poorly soluble natural polyphenols curcumin and resveratrol.

62 racellular co-release of the chemosensitizer curcumin and the encapsulated chemotherapeutic drug doxo

63 study, the interactions of beta-casein with curcumin and vitamin D3 under the same physico-chemical

64 reatment with SIRT1 activators (resveratrol, curcumin) and agents that prevent NAD depletion (theophy

65 ve curcumin) to 146+/-3 degrees C (nanonized curcumin) and enthalpy from 27+/-2J/g to 3.5+/-1J/g.

66 examine the effect of vanillin, resveratrol, curcumin, and epigallocatechin-3-gallate (EGCG) on the a

67 le of alternative therapies like probiotics, curcumin, and fecal microbiota transplantation in the ma

68 es, such as n-3 polyunsaturated fatty acids, curcumin, and fermentable fiber, have been proposed to e

69 Baicalein, curcumin, and rifampicin showed concentration-dependent

70 circulating tumor cells (CTCs), DNA/RNA, and curcumin, and the devices were optimized for POC use.

71 ide sequence, while those of resveratrol and curcumin are non-specific in that they stem from strong

72 Health-promoting effects of curcumin are well-known; however, curcumin has a very lo

73 Thus, identification of curcumin as a potential therapeutic for treating OM is o

74 Here, we identified curcumin as a pro-drug that requires oxidative activatio

75 gative effect on the antioxidant activity of curcumin as assessed by the DPPH and ABTS assays.

76 inylhydrazide, epigallocatechin gallate, and curcumin as reducing and stabilizing agents.

77 s the saffron authenticity marker, and using curcumin as the non-isotopic isobaric internal standard.

78 ibility of producing proliposomes containing curcumin, as well as liposome dispersions, using differe

79 exhibited a lower degradation rate than free curcumin at 60 degrees C.

80 fraction showed a compact complexation with curcumin at pH 3.0 with excellent aqueous solubility, st

81 vent in microextraction study to extract the curcumin at pH 4.0.

82 Here, we tested the efficacy of 1.5% dietary curcumin at promoting resilience to chronic social defea

83 ils (ETO-curcumin) in comparison to standard curcumin at three specific doses (0, 5, 25 or 50 mg/kg),

84 icated to obtaining a small library of novel curcumin-based analogues, and a number of potent and bal

85 with 0.4, 4.0, and 40mug/ml nanoencapsulated curcumin before and after simulated gastric and intestin

86 The K(D) value for curcumin-beta-casein interaction has been successfully e

87 Resveratrol and curcumin bind only to the hydrophobic residues near pept

88 Bovine serum albumin (BSA)/curcumin binding and dye photodegradation stability were

89 gnificantly enhanced the bioaccessibility of curcumin by 173-fold when compared to the original curcu

90 as also enhanced due to higher solubility of curcumin by CyD inclusion complex.

91 nal stability tests showed that solutions of curcumin can be stable up to five months when concealed

92 BSA/curcumin complex showed 1:1 stoichiometry, but the therm

93 he thermal stability of Alg and Cur at algae/curcumin complex was 3.8% and 33% higher than their free

94 For the unfolded BSA/curcumin complex, it was found thatp DeltaH(o)F=-16.12kJ

95 The curcumin concentration in enriched DES phase was analyze

96 oencapsulation structures increased with the curcumin content by incorporation of curcumin microcryst

97 In addition, the curcumin content retained in the powders ranged from 67

98 TWPC-SD showed higher total phenolic and curcumin contents compared to TWPC-FMD (p < 0.05).

99 lusion, we suggest that combination of OXA + Curcumin could be an effective treatment, for which CXCL

100 Curcumin (Cur) has been reported to have anti-hepatocell

101 Curcumin (CUR) is a natural extract from the plant Curcu

102 Curcumin (CUR) is a well-known natural compound, which e

103 Curcumin (Cur), a polyphenols with pharmacological funct

104 drolysate (LSPH) with a lipophilic molecule, curcumin (CUR), and its effect on curcumin in vitro bioa

105 flammatory molecules, the natural polyphenol curcumin (CURC) and the corticosteroid dexamethasone (DE

106 The antioxidant effect of curcumin in Curcumin/CyD webs was also enhanced due to higher solubi

107 Both Curcumin/CyD webs were produced in the form of free-stan

108 lity and antioxidant property of curcumin in Curcumin/CyD webs.

109 In the sensory analysis, the addition of curcumin decreased the acceptance of color's sample and

110 -3-methoxyphenyl)hex-5-ene-2,4-dione) in the curcumin degradation process has not been reported yet.

111 Curcumin degradation to ferulic acid and vanillin was ex

112 At elevated temperature curcumin degrades to trans-6-(4'-hydroxy-3'-methoxypheny

113 the experimental domain, half-life times of curcumin, demethoxycurcumin and bisdemethoxycurcumin wer

114 ethod for the analysis of main curcuminoids (curcumin, demethoxycurcumin and bisdemethoxycurcumin) pr

115 Our results show that the curcumin derivatives affect and modulate the tau oligome

116 We previously showed that novel curcumin derivatives affect preformed tau oligomer aggre

117 tested a small library of newly synthesized curcumin derivatives against preformed recombinant tau o

118 and dementia with Lewy bodies, we found that curcumin derivatives modulate the aggregation state of B

119 In this study, we show that curcumin, derived from Curcuma longa plant, long known f

120 previously a succinate ester prodrug of Cur, curcumin diethyl disuccinate (CurDD) with better chemica

121 Inhibition of CSN5 by curcumin diminished cancer cell PD-L1 expression and sen

122 led nanoparticle formula of amphiphilic poly(curcumin-dithiodipropionic acid)-b-poly(ethylene glycol)

123 Chronic daily oral curcumin dosing led to tumor accumulation of curcumin an

124 Functional validations confirmed that curcumin downregulates cellular protein synthesis, and i

125 rystallinity and maximize the utilization of curcumin due to increased bioaccessibility.

126 We found that administration of curcumin during CSDS produced a 4.5-fold increase in str

127 tric digestion in influencing the release of curcumin during gastrointestinal digestion.

128 The present paper shows that curcumin easily transforms into ketonic/enolic structura

129 thout a STAT3 inhibitor (S3I-201 or micellar curcumin, eight arms).

130 videnced that non-polar microenvironment for curcumin embedded in nanogels was strengthened, which th

131 The curcumin encapsulated NLC (CUR-NLC) was produced and opt

132 tested five candidate compounds: rifampicin, curcumin, epigallocatechin-3-gallate, myricetin, and scy

133 ts (l-ascorbic acid, caffeic acid, caffeine, curcumin, (-)-epigallocatechin gallate (EGCG), gallic ac

134 The encapsulated curcumin exhibited a lower degradation rate than free cu

135 Moreover, curcumin exhibited sustained release profile from crossl

136 It is not known how oral curcumin exhibits chemopreventive activity.

137 Curcumin exhibits potent anti-inflammatory properties bu

138 ation before extraction, the water insoluble curcumin extract could be solubilized indefinitely in an

139 LPS-activated RAW264.7 macrophages show that curcumin facilitates its anti-inflammatory action by ind

140 For native BSA/curcumin, fluorescence indicated an enthalpic and entrop

141 Fs, which can be used to store and stabilize curcumin for food applications.

142 this study we utilized a novel water-soluble curcumin formulation (CDC) and delivered it directly int

143 Curcumin found in the spice turmeric derived from the Cu

144 pH 6.0 were used for the preconcentration of curcumin from sample matrix.

145 d sweet pepper, piperine from ground pepper, curcumin from turmeric and curry, and myristicin from nu

146 and Gram-positive bacteria was observed when curcumin-functionalized endotracheal (ETT-curc) was used

147 e highest impregnation capacity was 224.2 mg curcumin/g NSA.

148 s of magnitude compared to free curcumin and curcumin:gamma-CD at pH 11.5.

149 lts in formation of a unique complex between curcumin, gammaCD and potassium cations.

150 We propose curcumin glucuronide is an inflammation-responsive natur

151 ency of curcumin and decreased the amount of curcumin-glutathione adducts in cells.

152 To identify the curcumin governed regulatory action on protein interacti

153 regation is as follows: EGCG > resveratrol > curcumin > vanillin, consistent with experimental findin

154 effects of curcumin are well-known; however, curcumin has a very low bioavailability due to its cryst

155 Curcumin has anti-inflammatory and antioxidant effects a

156 Addition of vitamin D and curcumin has been shown to increase the efficacy of IBD

157 linded, placebo controlled clinical trial of curcumin has been successful.

158 Curcumin has been successfully encapsulated in cyclodext

159 r, the fluorescence quenching data show that curcumin has higher affinity to beta-casein (K(A) = 23.5

160 Curcumin has recently been classified as both a PAINS (p

161 odified compound based on natural di-ketonic curcumin, has been shown to reduce bone loss and inflamm

162 e spice turmeric, with its active polyphenol curcumin, has been used as anti-inflammatory remedy in t

163 Many cellular targets of curcumin have been identified, but how such a wide range

164 results suggest that less polar analogues of curcumin have potent cytotoxicity in vitro.

165 The aqueous solutions of curcumin/HP-beta-CyD and curcumin/HP-gamma-CyD were yiel

166 queous solutions of curcumin/HP-beta-CyD and curcumin/HP-gamma-CyD were yielded uniform fiber morphol

167 Curcumin/Hydroxypropyl-beta-Cyclodextrin (HP-beta-CyD) a

168 xypropyl-beta-Cyclodextrin (HP-beta-CyD) and Curcumin/Hydroxypropyl-gamma-Cyclodextrin (HP-gamma-CyD)

169 However, ETO-curcumin improved disease activity index (DAI) dose-depe

170 s successful in retarding the degradation of curcumin in alkaline media (only 25-28 40% degraded in 1

171 All novel compounds were more effective than curcumin in apoptosis induction and cell cycle arrest at

172 e also made to enhance the solubilization of curcumin in aqueous equimolar mixed surfactant systems.

173 The antioxidant effect of curcumin in Curcumin/CyD webs was also enhanced due to h

174 e the solubility and antioxidant property of curcumin in Curcumin/CyD webs.

175 was successfully applied to determination of curcumin in food and herbal tea samples.

176 s been developed for the preconcentration of curcumin in food samples prior to its spectrophotometric

177 lied for the extraction and determination of curcumin in food samples.

178 proaches confirm the release of encapsulated curcumin in intestinal compartment without any significa

179 nd uncover the full therapeutic potential of curcumin in lung inflammation, in this study we utilized

180 GILZ was inducible by curcumin in macrophage cell lines, primary human monocyt

181 Oral administration of curcumin in mouse tumor models generated significant tum

182 h synthetic antioxidant and microcrystals of curcumin in relation to its physicochemical and sensoria

183 he results obtained suggest the potential of curcumin in replacing synthetic antioxidants in cooked m

184 The concentration of curcumin in the bioaccessible fraction was improved from

185 Concerning the high solubility of curcumin in the examined ternary mixtures, it was attemp

186 the glucuronide resulted in the formation of curcumin in the tumor tissue.

187 Most importantly, the stability of curcumin in this complex was enhanced by at least 3 orde

188 The likely false activity of curcumin in vitro and in vivo has resulted in >120 clini

189 molecule, curcumin (CUR), and its effect on curcumin in vitro bioaccessibility/stability, functional

190 tion containing essential turmeric oils (ETO-curcumin) in comparison to standard curcumin at three sp

191 In contrast, treatment of cells with curcumin increased the number of bleaching steps.

192 in-silico study will help to understand how curcumin induces its anti-cancerous, anti-inflammatory,

193 pe and GILZ knock-out mice demonstrated that curcumin inhibits the activity of inflammatory regulator

194 eta40 differ only near the C-terminus, where curcumin interacts, while Zn(2+) interacts near the N-te

195 from 0.003 to 0.125 mg/mL by impregnation of curcumin into NSAs (42-fold).

196 Curcumin is a constituent (up to approximately 5%) of th

197 Curcumin is a natural bioactive compound with poor water

198 Curcumin is a phenolic compound produced by some plants,

199 Curcumin is a powerful coloring agent widely used in the

200 Curcumin is an important bioactive component of turmeric

201 istry of curcumin and provides evidence that curcumin is an unstable, reactive, nonbioavailable compo

202 Curcumin is known from its lability, however, the struct

203 Although curcumin is the most studied active constituents of turm

204 riments, even 28.8% or 20.6% of the degraded curcumin is transformed to feruloyloacetone during 2 h h

205 e (nFTP) technology and investigated whether curcumin leads to intracellular AD pathologic changes.

206 We first demonstrated that curcumin, like docetaxel (DTX), can selectively target C

207 Interestingly, dissolving the curcumin loaded CD-MOFs crystals in water results in for

208 Finally, the curcumin-loaded liposomes preserved up to 63% of the bio

209 ty Pathway Analysis(TM) (IPA) suggested that curcumin may exert its anticancer effects over multiple

210 promotes resilience to CSDS and suggest that curcumin may prevent the emergence of a range of anxiety

211 cumin remained constant, suggesting that ETO-curcumin may provide superior anti-inflammatory efficacy

212 The mortadella with curcumin microcrystals showed significantly lower TBARS

213 ith the curcumin content by incorporation of curcumin microcrystals upon electrospraying.

214 gs deduce a precise molecular mechanism that curcumin might exert in the system.

215 plexation enhanced the aqueous solubility of curcumin more than 856-fold.

216 report a poly(lactic-co-glycolic acid) based curcumin nanoparticle formulation (Nano-CUR).

217 did not create any chemical bonding between curcumin nanoparticles and the NSA matrix.

218 We further show that curcumin nanoparticles enhance the capacity of BCG to in

219 Here, we show that curcumin nanoparticles enhance various antigen-presentin

220 Thus, curcumin nanoparticles hold promise for enhancing the ef

221 Curcumin nanoparticles significantly enhanced the bioacc

222 rmation method to generate low-crystallinity curcumin nanoparticles to enhance the bioavailability of

223 The average particle size of the curcumin nanoparticles was 66 nm.

224 The millet protein-curcumin nanoparticles were spherical with diameter arou

225 is is a novel approach to produce food grade curcumin nanoparticles with reduced crystallinity and ma

226 y of 93%) were employed as a mold to produce curcumin nanoparticles with the help of supercritical ca

227 Bioactivation of curcumin occurred readily in vitro, which may explain th

228 We measure the effects of Zn(2+) and curcumin on Abeta40, and compare these with their previo

229 ve natural prodrug that is converted back to curcumin on demand at the site of action.

230 However, the effects of curcumin on intracellular AD pathologic processes remain

231 The current study examines effect of curcumin on: 1) systemic T helper 17 (Th17) cell respons

232 ein that were decreased by pretreatment with curcumin or an unstable analog but not by a stable analo

233 tyle modification advice plus either 1500 mg curcumin or the same amount of placebo for 12 weeks.

234 of the antiepileptic efficacy (for example, curcumin) or antiepileptogenic affect (for example, ator

235 The concomitant combination of Curcumin + OXA was more effective and synergistic in cel

236 ximately 15mN/m in the presence of amorphous curcumin particles in water phase compared to crystallin

237 After nanonization, native crystalline curcumin particles were converted into amorphous, nanosi

238 In this study, nano-sized amorphous curcumin particles were fabricated using nanonization te

239 icles in water phase compared to crystalline curcumin particles.

240 BSA (mainly native) increased the curcumin photodegradation stability.

241 work describes ETT's functionalization with curcumin photosensitizer, as well as its evaluation in P

242 d gene expression alterations of a specific, curcumin preparation containing essential turmeric oils

243 r the effects of herbs (such as cannabis and curcumin), probiotics, acupuncture, exercise, and mind-b

244 provide the first preclinical evidence that curcumin promotes resilience to CSDS and suggest that cu

245 cted top five ranked phenolics (Resveratrol, Curcumin, Quercetin, Epigallocatechin Gallate, and Genis

246 tiple-ring compounds, EGCG, resveratrol, and curcumin, redirect Abeta(17-36) from a fibrillar aggrega

247 Direct pulmonary delivery of solubilized curcumin reduces severity of lethal pneumonia.

248 e the anti-inflammatory efficacy of standard curcumin remained constant, suggesting that ETO-curcumin

249 Intriguingly, curcumin remarkably reduced the level of intracellular o

250 the selection of key regulatory proteins of curcumin-rewired PIN.

251 Thus, our results provided evidence that curcumin's mechanism of action in attenuating AD patholo

252 TWPC containing 3.6 mg of curcumin showed good acceptability.

253 e inconclusive results in human studies with curcumin so far.

254 Curcumin solubility in binary mixtures consisting of eth

255 physicochemical properties of self-assembled curcumin-soluble soybean polysaccharide (SSPS) nanoparti

256 one during 2 h heating of alkaline or acidic curcumin solution, respectively.

257 ely 90% were self-assembled after increasing curcumin-SSPS mixture to pH 12.0 and lowering pH to 7.0.

258 Curcumin stabilized O/W emulsion has an initial droplet

259 ity for the hydrophobic small drug molecules curcumin, sulindac, and triamterene is demonstrated.

260 present study was to evaluate the effects of curcumin supplementation on inflammatory indices, and he

261 Our results indicated that curcumin supplementation plus lifestyle modification is

262 Curcumin supplementation was associated with significant

263 Curcumin suppressed CXCL5 expression by direct inhibitio

264 A synthetic monoketone analog of curcumin, termed 3, 5-bis (2-flurobenzylidene) piperidin

265 melting point from 177+/-1 degrees C (native curcumin) to 146+/-3 degrees C (nanonized curcumin) and

266 Curcumin, together with demethoxycurcumin and bisdemetho

267 lytical and food processing point of view as curcumin transformation products can be mistakenly treat

268 n from its lability, however, the structural curcumin transformations and the formation of hydroxy an

269 Curcumin-treated mice showed significant decreases in bo

270 more efficiently down-regulated after OXA + Curcumin treatment as compared to the sensitive cells.

271 Our results suggest that curcumin treatment induces HuR expression.

272 Curcumin treatment polarized surviving M-MDSCs toward CC

273 AP2 protein levels in both cell lines whilst curcumin treatment reduced ATRA-mediated AGAP2 increase.

274 riodontitis; 2) group 2 = periodontitis with curcumin treatment; 3) group 3 = periodontally healthy w

275 ent; 3) group 3 = periodontally healthy with curcumin treatment; and 4) group 4 = periodontally healt

276 sent study showed that both ETO and standard curcumin treatments provided protection against DSS-indu

277 ifferent from control at any x-ray dose, all curcumin treatments yielded significant differences at a

278 ethod for separation and preconcentration of curcumin using deep eutectic solvent known as green solv

279 in, umbelliferone, esculetin, hesperetin and curcumin, using the orthogonal design, uniform design an

280 with distinct intracellular composition and curcumin was a model encapsulated bioactive.

281 The PIN rewired by curcumin was a scale-free, extremely linked biological s

282 Curcumin was administered via oral gavage (30 mg/kg/d) f

283 Curcumin was decreased the most by SD (72%), followed by

284 dynamic and static quenching mechanisms and curcumin was distributed in a palisade layer of mixed ag

285 Curcumin was extracted from Curcuma Longa employing a gr

286 In our study, curcumin was identified as a lead compound for the simul

287 stion indicated that the bioaccessibility of curcumin was increased from 67% to 95% post complexation

288 aliva) revealed that the water-solubility of curcumin was prominently improved by inclusion complexat

289 Curcumin was totally preserved without any loss during t

290 lity to solubilize a model hydrophobic drug, curcumin, was also explored.

291 EGCG, gallic acid, and curcumin were identified as a multifunctional compounds,

292 While 64% of defeated mice on curcumin were resilient (responders), the remaining 36%

293 Although the overall effects of curcumin were striking, we identified two distinct respo

294 6-bis benzylidine cyclohexanone analogues of curcumin were synthesized, and their inhibitory effects

295 Two natural compounds (quercetin and curcumin) were tested as sensitizing or protecting agent

296 present work focuses on the natural product curcumin, which has previously been reported to inhibit

297 eported that replacement of two OH groups in curcumin with less polar groups like methoxy increases i

298 redict the binding position and mechanism of curcumin with self-assemblies.

299 Microencapsulation of curcumin within the proposed hybrid structures significa

300 The internal standard curcumin yielded good linearity (R(2) = 0.994), and with