ライフサイエンスコーパス: cysteine-sulfenic acid

1 oteins containing an active site cysteine or cysteine sulfenic acid.

2 d M785 in the C-Ala domain) were modified to cysteine sulfenic acid and methionine sulfoxide, respect

3 served cysteine residue to the corresponding cysteine-sulfenic acid, and perhaps to higher oxidation

4 Since cysteine sulfenic acids are known to play an important f

5 uction of hydrogen peroxide to water using a cysteine-sulfenic acid as a secondary redox center.

6 attacking the peroxide substrate, forming a cysteine sulfenic acid at the active site.

7 The function of the cysteine sulfenic acid coordinated to the iron active si

8 ion as a general trap for proteins that form cysteine sulfenic acid (Cys-SOH) in vivo.

9 As a posttranslational protein modification, cysteine sulfenic acid (Cys-SOH) is well established as

10 4-nitrobenzo-2-oxa-1,3-diazole to identify a cysteine sulfenic acid (Cys-SOH) modification that forms

11 own to contain post-translationally modified cysteine sulfenic acids (Cys-SOH).

12 for more than 20 years that unusually stable cysteine-sulfenic acid (Cys-SOH) derivatives can be intr

13 We have proposed a cysteine-sulfenic acid (Cys-SOH) structure for the oxidi

14 Post-translational redox generation of cysteine-sulfenic acids (Cys-SOH) functions as an import

15 strongly supporting its identification as a cysteine sulfenic acid (Cys46-SOH).

16 cluding the condensation of two molecules of cysteine sulfenic acid (CySOH) to give CyS(=O)SCy.

17 Cysteine sulfenic acid CysS(O)H is shown to be formed fo

18 e have examined the importance of reversible cysteine sulfenic acid formation in naive CD8(+) T cell

19 r, these results demonstrate that reversible cysteine sulfenic acid formation is an important regulat

20 re sensitive to the inhibition of reversible cysteine sulfenic acid formation than IFN-gamma.

21 To examine the contribution of reversible cysteine sulfenic acid formation to T cell activation, i

22 Cysteine sulfenic acid has been generated in alkaline aq

23 ion reaction and the subsequent reactions of cysteine sulfenic acid have been studied by stopped-flow

24 Cysteine sulfenic acids have been shown to play diverse

25 e of the W197I variant is the first reported cysteine sulfenic acid in a serine esterase.

26 Increased ROI resulted in elevated levels of cysteine sulfenic acid in the total proteome.

27 peroxidase, which use a single redox-active cysteine-sulfenic acid in catalysis.

28 a-1, 3-diazole (NBD-Cl), it was shown that a cysteine sulfenic acid intermediate (Cys-SOH) is formed

29 nism for reversible inactivation involving a cysteine sulfenic acid intermediate is proposed.

30 of reaction intermediates and implicate the cysteine-sulfenic acid ligand as the catalytic nucleophi

31 nds and is sensitive to oxidation; thus, the cysteine sulfenic acid may play a role in the regulation

32 ith increased oxidant damage, which led to a cysteine sulfenic acid modification in endothelin B rece

33 r substitution at position 420 that mimics a cysteine sulfenic acid results in a ~4-fold increase in

34 In contrast, the E18D mutation stabilizes a cysteine-sulfenic acid that is readily reduced to the th

35 t reaction suggests that the condensation of cysteine sulfenic acid to give cysteine thiosulfinate es

36 emonstrated that the reversible formation of cysteine sulfenic acid was critical for ERK1/2 phosphory

37 edione (dimedone), which covalently binds to cysteine sulfenic acid, were added to cultures.

38 lowed by rate-limiting comproportionation of cysteine sulfenic acid with cysteinate to give cystine.

39 lowed by rate-limiting comproportionation of cysteine sulfenic acid with cysteinate to give cystine.

40 ster can be competitive with the reaction of cysteine sulfenic acid with cysteine.

41 chanism including the transient formation of cysteine sulfenic acid within AhpC is proposed.