ライフサイエンスコーパス: cytolethal distending toxin

1 gene (encoding subunit B of the H. hepaticus cytolethal distending toxin).

2 ell vacuoles and induces apoptotic death via cytolethal distending toxin.

3 ll as live bacteria and do not depend on the cytolethal distending toxin.

4 e genomic island that carries genes encoding cytolethal distending toxins.

5 ed in NBM, notably diarrhea-associated cdtB (cytolethal distending toxin [46%]) and urinary tract inf

6 We concluded that cytolethal distending toxin activity is a characteristic

7 Cytolethal distending toxin activity is a potential viru

8 ys for the presence of the cdtB gene and for cytolethal distending toxin activity.

9 ell established, but the association between cytolethal distending toxin and disease is incompletely

10 Cytolethal distending toxins are produced by a small but

11 ecapitulate the evolution of two toxin genes-cytolethal distending toxin B (cdtB) and apoptosis induc

12 , the commercially available version of anti-cytolethal distending toxin B and anti-vinculin antibodi

13 -terminal Cys residue, a CdtB homologue from cytolethal distending toxin can form a functional comple

14 The bacterial genotoxins cytolethal distending toxin (CDT) and colibactin cause s

15 Haemophilus ducreyi makes cytolethal distending toxin (CDT) and hemolysin.

16 r actinomycetemcomitans strains that express cytolethal distending toxin (Cdt) are associated with lo

17 tis in susceptible mouse strains, produces a cytolethal distending toxin (CDT) consisting of CdtA, Cd

18 cobacter hepaticus expresses a member of the cytolethal distending toxin (CDT) family of bacterial cy

19 activity that represent a new member of the cytolethal distending toxin (CDT) family of bacterial to

20 Cytolethal distending toxin (CDT) from the diarrheagenic

21 ivo experiments, we recently showed that the cytolethal distending toxin (Cdt) from the periodontal p

22 IL-8 secretion was reduced by flagellum and cytolethal distending toxin (CDT) gene mutants, treatmen

23 o determine the role of the virulence factor cytolethal distending toxin (CDT) in the pathogenesis of

24 Cytolethal distending toxin (CDT) induces cell cycle arr

25 The tripartite cytolethal distending toxin (CDT) induces cell cycle arr

26 Cytolethal distending toxin (CDT) is a multisubunit prot

27 Cytolethal distending toxin (CDT) is a newly described t

28 The Actinobacillus actinomycetemcomitans cytolethal distending toxin (Cdt) is a potent immunotoxi

29 to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon the

30 to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon the

31 The cytolethal distending toxin (Cdt) is produced from a num

32 Because cytolethal distending toxin (CDT) may be a virulence fac

33 The cytolethal distending toxin (Cdt) of Actinobacillus acti

34 The cytolethal distending toxin (CDT) of Actinobacillus acti

35 The cytolethal distending toxin (CDT) of Campylobacter jejun

36 The cytolethal distending toxin (CDT) of Haemophilus ducreyi

37 herichia coli cdtABC genes that comprise the cytolethal distending toxin (CDT) of this enteric pathog

38 Campylobacter jejuni-derived cytolethal distending toxin (CDT) promotes CRC metastasi

39 ith the Actinobacillus actinomycetemcomitans cytolethal distending toxin (Cdt) results in dose-depend

40 hat the CdtB polypeptide of Escherichia coli cytolethal distending toxin (CDT) shares significant pat

41 Campylobacter jejuni encodes a cytolethal distending toxin (CDT) that causes cells to a

42 egatibacter actinomycetemcomitans produces a cytolethal distending toxin (Cdt) that inhibits the prol

43 Haemophilus ducreyi expresses a soluble cytolethal distending toxin (CDT) that is encoded by the

44 Haemophilus ducreyi expresses a soluble cytolethal distending toxin (CDT) that kills HeLa, HEp-2

45 A genetic locus for a cytolethal distending toxin (CDT) was identified in a po

46 of 20 Escherichia coli strains that produce cytolethal distending toxin (CDT) were analyzed for thei

47 Moreover, the effects of the cytolethal distending toxin (CDT) were evaluated first b

48 hree membrane-associated protein subunits of cytolethal distending toxin (CDT) were unable to induce

49 cytolethal distending toxin (Cdt), 4',6-diamidino-2-phen

50 Many H. ducreyi strains express cytolethal distending toxin (CDT), and recombinant CDT c

51 The bacterial genotoxin, cytolethal distending toxin (CDT), causes DNA damage in

52 Abbreviations: cytolethal distending toxin (Cdt), connective tissue (CT

53 The cytolethal distending toxin (Cdt), expressed by the peri

54 A genetically modified cytolethal distending toxin (Cdt), from the periodontal

55 ance of potential virulence factors, such as cytolethal distending toxin (CDT), in vivo are poorly un

56 polymorphic regions in the leukotoxin (lkt), cytolethal distending toxin (cdt), major fimbrial subuni

57 The cytolethal distending toxin (Cdt), produced by some clin

58 enic bacteria have evolved a toxin, known as cytolethal distending toxin (CDT), that has the ability

59 athogens encode a multisubunit toxin, termed cytolethal distending toxin (CDT), that induces cell cyc

60 ampylobacter jejuni produces a toxin, called cytolethal distending toxin (CDT), which causes direct D

61 Many bacterial pathogens encode the cytolethal distending toxin (CDT), which causes host cel

62 in survival and pathogenesis, including the cytolethal distending toxin (CDT).

63 They possess virulence factors, such as cytolethal distending toxin (CDT).

64 em, but the genome does not harbor genes for cytolethal distending toxin (cdt).

65 and animals were examined for production of cytolethal distending toxin (Cdt).

66 known heat-labile toxins, a hemolysin and a cytolethal distending toxin (CDT).

67 Campylobacter jejuni produces a toxin called cytolethal distending toxin (CDT).

68 ks), cytotoxic necrotizing factor (cnf), and cytolethal distending toxin (cdt).

69 al adhesion; (b) the newly discovered toxin, cytolethal distending toxin (CDT); and (c) a secreted ch

70 s an immunosuppressive factor encoded by the cytolethal distending toxin (cdt)B gene, which is homolo

71 s an immunosuppressive factor encoded by the cytolethal distending toxin (cdt)B gene.

72 dtB gene, which is homologous to a family of cytolethal distending toxins (Cdt) expressed by several

73 dtB gene, which is homologous to a family of cytolethal distending toxins (Cdt) expressed by several

74 e, one of three genes encoding the family of cytolethal distending toxins (Cdt).

75 ontains intact homologs of the gene encoding cytolethal distending toxin (cdtB), which interrupts the

76 n a validated rat model of IBS-D (induced by cytolethal distending toxin [CdtB] inoculation).

77 Cytolethal distending toxins (CDTs) are multisubunit pro

78 Cytolethal distending toxins (CDTs) are tripartite prote

79 Cytolethal distending toxins (CDTs) block cell division

80 The cytolethal distending toxins (CDTs) compose a subclass o

81 creens as illustrated here for the family of cytolethal distending toxins (CDTs).

82 ni and Campylobacter coli, the production of cytolethal distending toxin correlated positively (P < 0

83 Abbreviations: Cdt, cytolethal distending toxin; CSC, cancer stem cells; HNS

84 (M fimbriae), gafD (G fimbriae), cnf1, cdtB (cytolethal distending toxin), cvaC (colicin V), and ibeA

85 Intoxication by cytolethal distending toxin depends on assembly of CdtB,

86 CR quantitation of the H. hepaticus-specific cytolethal distending toxin gene and showed similar anim

87 Sequence analysis of the cytolethal distending toxin gene cluster (cdt) also disc

88 so identified genes needed for the action of cytolethal distending toxin, including a cell-surface pr

89 i (7.9%), cell-detaching E. coli (6.9%), and cytolethal distending toxin-producing E. coli (0.9%).

90 Overall the pathotypes, apart from cytolethal distending toxin-producing E. coli, were reco

91 e demonstrated the role of LuxS in motility, cytolethal distending toxin production, agglutination, a

92 , type 6 secretion system needle protein, or cytolethal distending toxin revealed a direct correlatio

93 a new diagnostic assay: hemolysin E (HlyE), cytolethal distending toxin, S. Typhi lipopolysaccharide

94 erial genes encoding toxins of animal cells, cytolethal distending toxin subunit B (cdtB) and apoptos

95 The presence of cytolethal distending toxin was confirmed on the basis o

96 tB, a homologue of the active subunit of the cytolethal distending toxin, which causes DNA damage lea