ライフサイエンスコーパス: cytoplasmic

1 lete degradation of viral genomic RNA by the cytoplasmic 5'-3' exoribonuclease Xrn1 halted at the Xrn

2 This selection identified Xrn1p, the cytoplasmic 5'-to-3' exoribonuclease, as a cofactor of R

3 ug validated a role for Taok2 in favoring Lm cytoplasmic access.

4 mDia2 disrupts HSPC polarization and induced cytoplasmic accumulation of MAL, which deregulates the a

5 tes, the (G4C2)-RNA repeats-induced aberrant cytoplasmic accumulation of Ran.

6 ion of actin itself was revealed to regulate cytoplasmic actin polymerization through the formin INF2

7 d to regulate CRKL (CRK-like proto-oncogene, cytoplasmic adaptor) expression.

8 Cytoplasmic aggregated proteins are a common neuropathol

9 binding protein TDP-43 forms intranuclear or cytoplasmic aggregates in age-related neurodegenerative

10 f affected motor neuron cells, often forming cytoplasmic aggregates in the process.

11 US is a nuclear RNA-binding protein, and its cytoplasmic aggregation is a pathogenic signature of amy

12 ion of nonnative proteins, (ii) reduction of cytoplasmic aggresomes in cells expressing aggregation-p

13 In mammalian cells, eight cytoplasmic aminoacyl-tRNA synthetases (AARS), and three

14 regenerative proliferation, but YAP remained cytoplasmic and little proliferation occurred in mouse u

15 Three highly conserved protein loops linking cytoplasmic and membrane domains enable scalable energy

16 Nexus is a dynamic membrane organelle, with cytoplasmic and membrane-embedded proteins binding and d

17 ing glucose and fatty acid (FA) oxidation in cytoplasmic and mitochondrial compartments, we estimated

18 The missing link between cytoplasmic and mitochondrial glutamine metabolism is no

19 the detection of a multitude of membranous, cytoplasmic and nuclear antigens in whole mouse organs a

20 nimal and plant cells disassembles, allowing cytoplasmic and nuclear components to intermix(3).

21 epletion that is highlighted by preferential cytoplasmic and nuclear mono-methylation of H3 Lys 9 (H3

22 s the only glycosyltransferase that modifies cytoplasmic and nuclear protein by transfer of N-acetylg

23 al system to separate and thereby define the cytoplasmic and nuclear stages of infection by other vir

24 bryonic fibroblasts, its location was solely cytoplasmic, and it then failed to mediate cell death.

25 flagellin X, and perinuclear anti-neutrophil cytoplasmic antibodies) and 1129 proteins in each sample

26 The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV

27 Stress granules (SGs) are cytoplasmic assemblies of proteins and non-translating m

28 l actin rearrangements in response to auxin, cytoplasmic auxin (i.e. NAA) stimulated a lesser respons

29 leton response to auxin requires AUX1 and/or cytoplasmic auxin.

30 y member, TRIM5alpha, has been shown to form cytoplasmic bodies involved in restricting retroviruses

31 -based intermediate filament meshwork and in cytoplasmic bodies.

32 In patient samples, cytoplasmic BOP1 was also inversely associated with over

33 volcanii involves the transient formation of cytoplasmic bridges between cells and is referred to as

34 Cytoplasmic bridges connected hyphae in field-collected

35 cleated erythroblasts and erythroblasts with cytoplasmic bridges indicating abnormal cytokinesis and

36 ells, makes protein-protein contact with the cytoplasmic C-tail domain of Canx.

37 ns are transported through, and a regulatory cytoplasmic C-terminal domain (CTD).

38 d by the phosphorylation of threonine in the cytoplasmic C-terminal domain, providing the first direc

39 type gene with one encoding Kcnt1(R455H), a cytoplasmic C-terminal mutation homologous to a human R4

40 Modulating cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) by endopl

41 ase-activated Ca(2+) (CRAC) channels elevate cytoplasmic Ca(2+) concentration, which is essential for

42 y mechanism of MCU-channel activity in which cytoplasmic Ca(2+) regulation of intermembrane space-loc

43 It caused inhibition at diastolic cytoplasmic [Ca(2+)] but not at Ca(2+) levels in the dya

44 n both induce persistent static elevation of cytoplasmic calcium levels that fade over developmental

45 ols respond to opioids ex vivo by increasing cytoplasmic calcium, a novel finding for OR signal trans

46 Inhibition of cytoplasmic cap methylation was also associated with mRN

47 is a key event in the transport of multiple cytoplasmic cargo (e.g., proteins, protein aggregates, l

48 Macroautophagy (autophagy) targets cytoplasmic cargoes to the lysosome for degradation.

49 embraned vesicles (autophagosomes) sequester cytoplasmic cargos, which are subsequently delivered to

50 Scribble and Yap1 coordinate to control cytoplasmic Cdc42 activity and HSC fate determination in

51 ccurs on the luminal side of the membrane by cytoplasmic Cdc48 action.

52 e for nuclear CELF1 functions as compared to cytoplasmic CELF1 functions in skeletal muscle wasting.

53 malian WRB/CAML) that captures the TA from a cytoplasmic chaperone (Get3 or TRC40, respectively).

54 TOP1cc localizes to cytoplasmic chromatin and TOP1 interacts with cGAS to en

55 cretory phenotype (SASP) through recognizing cytoplasmic chromatin during senescence.

56 ablish a HMGB2-TOP1cc-cGAS axis that enables cytoplasmic chromatin recognition and response to immune

57 h necessary and sufficient for cGAS-mediated cytoplasmic chromatin recognition and SASP during senesc

58 We propose that cytoplasmic cilia assembly requires the precise localiza

59 anogaster sperm), very little is known about cytoplasmic cilia assembly.

60 Cytoplasmic cilia, a specialized type of cilia in which

61 arized to the distal end of the cilia during cytoplasmic ciliogenesis in Drosophila sperm.

62 Many RNA viruses replicate in cytoplasmic compartments (virus factories or viroplasms)

63 ated with misfolded nascent chains move into cytoplasmic compartments enriched in factors that facili

64 PINCH-1 is a cytoplasmic component of the cell-extracellular matrix (

65 tophagy is a catabolic process through which cytoplasmic components are degraded and recycled in resp

66 Here we show in HeLa cells that large cytoplasmic components are displaced before nuclear enve

67 Macroautophagy, the degradation of cytoplasmic content by lysosomal fusion, is an evolution

68 r organelles such as mitochondria as well as cytoplasmic content must also be properly distributed be

69 ionarily conserved cellular process by which cytoplasmic contents are targeted for lysosomal digestio

70 ved intracellular clearance pathway in which cytoplasmic contents are trafficked to the lysosome for

71 Autophagy involves engulfment of cytoplasmic contents by double-membraned autophagosomes,

72 rved cellular pathway by which cells deliver cytoplasmic contents to lysosomes for degradation.

73 ons at significantly higher rates than their cytoplasmic counterparts, resulting in foreshortened and

74 nding of the CheY family protein CleD to the cytoplasmic Cring switch complex, the control center of

75 Biochemical experiments indicated that cytoplasmic Cx43 had a half-life that was 50% shorter th

76 hese results establish CydDC as a reducer of cytoplasmic cystine, as opposed to an l-cysteine exporte

77 N-Glycanase 1 (NGLY1) is a cytoplasmic deglycosylating enzyme.

78 d that the inhibition occurred downstream of cytoplasmic DNA sensing.

79 d nuclear defects and GI generating aberrant cytoplasmic DNA, however simultaneous miR-181a mediated

80 SD), a central pore-gate domain, and a large cytoplasmic domain (CTD) that contains the Ca(2+) sensor

81 ctivation involves upward translation of the cytoplasmic domain and formation of state-dependent inte

82 to both forming and mature CNS nodes via its cytoplasmic domain and requires intact paranodes.

83 ompared accumulation of NF186 ectodomain and cytoplasmic domain constructs in WT versus paranode defe

84 onine motif (T788/T789) in the integrin beta cytoplasmic domain increases integrin activity.

85 e found that incorporation of the CD3epsilon cytoplasmic domain into a second-generation chimeric ant

86 e show here that the KRK motif in the PlxnA4 cytoplasmic domain is required for Sema3A-mediated corti

87 The cytoplasmic domain of BRI1 contains five putative canoni

88 biochemical measurement-that SarA mimics the cytoplasmic domain of glycoprotein 130 (gp130, IL6ST).

89 We show that phosphorylation of the cytoplasmic domain of p14 triggers N-WASP-mediated assem

90 the GTP-bound state, RhoJ interacts with the cytoplasmic domain of PlexinD1.

91 he structure of its interacting partner, the cytoplasmic domain of PscD (SctD).

92 The cytoplasmic domain of PscD forms a forkhead-associated (

93 the KRK motif within the Plexin-A4 receptor cytoplasmic domain, are required to coordinate the downs

94 1229) at the ankyrin binding motif of the L1 cytoplasmic domain, leading to the dissociation of L1 fr

95 ols fates of mRNAs localized within the same cytoplasmic domain.

96 ct prosurvival signals mediated by the 4-1BB cytoplasmic domain.

97 rrantly persists into adulthood, whereas the cytoplasmic domain/transport-dependent targeting is impa

98 ies, here we combined the DrBpP-PCM with the cytoplasmic domains of EGFR and FGFR1.

99 h at least three distinct regions within the cytoplasmic domains of the channel that contain conserve

100 Many immunoreceptors have cytoplasmic domains that are intrinsically disordered (i

101 eins with small ER luminal domains and large cytoplasmic domains.

102 d tandem kinase and endoribonuclease (RNase) cytoplasmic domains.

103 anism that mammalian cells utilize to detect cytoplasmic dsDNA from incoming viruses, bacteria, or se

104 Cytoplasmic dynein is a eukaryotic motor protein complex

105 Cytoplasmic dynein is an AAA(+) motor that drives the tr

106 Cytoplasmic dynein is the primary motor for microtubule

107 al cortex involves Nesprin-2, which recruits cytoplasmic dynein, kinesin, and actin to the nuclear en

108 It has been shown that cytoplasmic dynein, targeted to cortical actin, removes

109 Cytoplasmic dynein-1 is a molecular motor that drives ne

110 al channels and annular cylinders, even when cytoplasmic dynein-dependent pulling mechanisms were inh

111 Although many apoplastic and cytoplasmic effectors have been reported, nuclear effect

112 ated protein 1 (LRP1), led to recruitment of cytoplasmic EHD1 to endosomal membranes.

113 itable photolabeling of amino acids near the cytoplasmic end of the beta subunit M4 (beta3Pro-415, be

114 g residue of the EAAT2 anion channels at the cytoplasmic entrance into the ion conduction pathway.

115 pling protein, TraD, which is located at the cytoplasmic entrance of the F-encoded type IV secretion

116 Cytoplasmic envelopment depends upon interactions betwee

117 The Src homology phosphatase 2 (SHP2) is a cytoplasmic enzyme that mediates signaling induced by mu

118 ne transfer (HGT), including conjugation and cytoplasmic exchange through nanotubes.

119 rgy intensive to enforce membrane fusion and cytoplasmic expansion.

120 lear eIF5A during anaerobiosis, enabling the cytoplasmic export of eIF5A/Tsc2 mRNA complexes for tran

121 this experimental regime in conjunction with cytoplasmic extract, a new study finds that microtubule

122 Around the neck of the FP on its cytoplasmic face is a structure called the flagellar poc

123 The cytoplasmic form of NOC is constitutively expressed and

124 E490del remained mostly cytoplasmic, forming punctate co-localisations with LC3,

125 Here, we identified a cytoplasmic function for Elp1 in sympathetic neurons tha

126 turnover of most epithelial cell types, the cytoplasmic function of YAP1 in epithelial cells has not

127 TMTs do not allow intercellular transfer of cytoplasmic GFP.

128 x1 in 20-30% of transfected cells in a novel cytoplasmic giantin-based intermediate filament meshwork

129 GFP-MuMx1 in Huh7 cells also associated with cytoplasmic giantin-based intermediate filaments, and su

130 reactive oxygen (ROS) production, increased cytoplasmic glycogen accumulation, mitochondrial dysfunc

131 IVCM showed diffuse cytoplasmic granular hyperreflectivity and rounded/ellip

132 RH domain interaction for phosphorylation of cytoplasmic GRK5 substrates.

133 t there was a displacement or replacement of cytoplasmic gross cystic disease fluid protein-15 and CK

134 We identify a Get2/CAML cytoplasmic helix that forms a "gating" interaction with

135 nctional zone trophoblast cells positive for cytoplasmic high temperature requirement A1 (Htra1), a m

136 We found that, on average, half of the cytoplasmic HIV-1 RNAs are being actively translated at

137 ed at clarifying whether inactivation of the cytoplasmic immunoglobulin tail tyrosine (ITT) motif in

138 as diffuse nuclear in one tissue and diffuse cytoplasmic in another but toxic in both).

139 isease duration-related increase in neuronal cytoplasmic inclusions in the dentate gyrus and cornu am

140 Semi-quantitative analysis of neuronal cytoplasmic inclusions in the hippocampus and parahippoc

141 on density of TDP-43 immunoreactive neuronal cytoplasmic inclusions in the neocortical regions.

142 e demonstrate that lanthanides are stored as cytoplasmic inclusions that resemble polyphosphate granu

143 inding to FUS and decreased the formation of cytoplasmic inclusions.

144 Cytoplasmic incompatibility (CI) is the most common symb

145 his new host, where it showed high levels of cytoplasmic incompatibility, enabling rapid invasion of

146 RP1 is an innate immune sensor that can form cytoplasmic inflammasome complexes.

147 host cytosol where it is protected from host cytoplasmic innate immune responses.

148 Despite having a network of cytoplasmic interconnections (plasmodesmata) facilitatin

149 substantial structural rearrangements at the cytoplasmic intersubunit interface.

150 ting that NI, although probably derived from cytoplasmic invaginations, are not just simple invaginat

151 proteins in the ER lumen, IRE1 activates its cytoplasmic kinase and ribonuclease domains to transduce

152 analyses reveal that the PBL13 receptor-like cytoplasmic kinase phosphorylates RBOHD's C-terminus and

153 or IRE1alpha resides in the ER and deploys a cytoplasmic kinase-endoribonuclease module to activate t

154 Receptor-like cytoplasmic kinases (RLCKs) such as ZED1, interact with

155 sterol and sphingomyelin, whereas the inner, cytoplasmic leaf is rich in phosphatidylserine and phosp

156 tric septum retracts, resulting in forespore cytoplasmic leakage and loss of DNA translocation.

157 However, the cytoplasmic level of l-cysteine must be tightly regulate

158 system to selectively manipulate the nucleo-cytoplasmic levels of acetyl-CoA using clustered regular

159 regarding regulation of InsP(3)R activity by cytoplasmic ligands and processes, its regulation by ER-

160 Here, we identify cytoplasmic linker-associated protein 2 (CLASP2), a +TIP

161 Here, we reveal that cytoplasmic linker-associated protein 2 (CLASP2), a key

162 photoautotrophic seedling growth, for which cytoplasmic lipid droplets (LDs) play a critical role as

163 We also discovered that Fabp5, an abundant cytoplasmic lipid-binding protein found in brain endothe

164 ALAL-1 is a TNFalpha- and NF-kappaB-induced cytoplasmic lncRNA that specifically interacts with SART

165 ansfected with CYLDM719V exhibited increased cytoplasmic localization of TDP-43 and shortened axons.

166 umenal/extracellular domains or shortening a cytoplasmic loop abolishes transport activity by both NP

167 consistent with the reported mapping of the cytoplasmic loop that contains the EDTEE sequence as a g

168 e residue (C621) promotes reorientation of a cytoplasmic loop to enhance nucleophilicity and modifica

169 ing motifs (AIMs) located at the C-terminus, cytoplasmic loop, and within the transmembrane segments.

170 Type C cytoplasmic male sterility (CMS-C) is the most commonly

171 tis, keratin and ubiquitin aggregates within cytoplasmic Mallory-Denk bodies, and changes of the intr

172 t mechanism by which cells can control their cytoplasmic mechanics.

173 athway transports folded proteins across the cytoplasmic membrane and has been implicated in virulenc

174 nd fully occluded cavity at the level of the cytoplasmic membrane boundary, with no ligand bound.

175 stator units that couple ion flow across the cytoplasmic membrane to generate torque.

176 hinery, which transports proteins across the cytoplasmic membrane.

177 a coli periplasm and that it depolarizes the cytoplasmic membrane.

178 to GM1-rich, liquid-ordered lipid domains on cytoplasmic membranes by using unroofed cells, which enc

179 3D analysis revealed cytoplasmic membranes directly adjacent to NE holes cont

180 ) are nonenveloped viruses that replicate in cytoplasmic membranous organelles called viral inclusion

181 stress-responsive transcription factors and cytoplasmic messenger ribonucleoprotein granules.

182 dation is reversible and is regulated by the cytoplasmic methionine sulfoxide reductase Mxr1 (MsrA) a

183 These phenotypes are partially caused by cytoplasmic mislocalization of Mitf/TFEB, a key transcri

184 roteins based on their surface charge, while cytoplasmic MLOs formed in AfrLEA6-transfected insect ce

185 -7), which raises the question of how larger cytoplasmic molecules are cleared from the nucleus.

186 An inner membrane assembly platform and a cytoplasmic motor controls pseudopilus assembly.

187 1/DCP1, the essential co-factor of the major cytoplasmic mRNA decapping enzyme, impacts normal develo

188 l decision-making cascade: the generation of cytoplasmic mRNA patterns via the control of transcripti

189 and quantify nuclear nascent transcripts and cytoplasmic mRNAs as a function of position along the ge

190 copical analyses showed that roasting caused cytoplasmic network disruption, with a loss of lipid com

191 unable to maintain higher expression of the cytoplasmic NF-kappaB inhibitor IkappaBalpha.

192 We measured the impact of cytoplasmic NOCT on the transcriptome and observed that

193 ssue of Cell, Zavaliev et al. determine that cytoplasmic NPR1-containing assemblies are consistent wi

194 t the substrate specificity underpinning the cytoplasmic O-glycosylation pathway that modifies all si

195 ctroscopy permits quantitative assessment of cytoplasmic oligomerization, while stepwise photobleachi

196 Here, we investigated whether cytoplasmic organelles-called intracellular vesicle clus

197 ed functionality mapped to the transmembrane/cytoplasmic part of alpaca BTN3.

198 However, timing and reason for this cytoplasmic passage are poorly understood.

199 Remarkably, after this cytoplasmic passage, the nuclear stability of telomerase

200 nditions that increase FUS accumulation into cytoplasmic phase-separated structures.

201 udy signal exchange in and out of the 200 nm cytoplasmic pole-organizing protein popZ (PopZ) microdom

202 regates of a prion-like RNA-binding protein, cytoplasmic polyadenylation element-binding (CPEB) prote

203 ription, but instead via binding of CPEB4 to cytoplasmic polyadenylation elements within the 3'-untra

204 se Mxr1 (MsrA) and a previously unidentified cytoplasmic pool of the reductase Mxr2 (MsrB).

205 After nerve injury, tSCs extend cytoplasmic processes between NMJs to guide axon growth

206 m (CNS) survey their surroundings with their cytoplasmic processes, phagocytose debris and rapidly re

207 APC is an essential component of a cytoplasmic protein complex that targets beta-catenin fo

208 regulator of G protein signaling 4 (RGS4), a cytoplasmic protein expressed in airway smooth muscle an

209 In Leishmania major, PRMT7 is a cytoplasmic protein implicit in pathogenesis with unknow

210 ved understanding of the role of O-GlcNAc in cytoplasmic protein quality control and proteostasis.

211 that in addition to poly ribosomes, soluble cytoplasmic proteins have a significant contribution in

212 d to FF, FFPE transcripts coding for nuclear/cytoplasmic proteins involved in DNA packaging, replicat

213 hat bacterially derived flavohemoglobins are cytoplasmic proteins required for nitric oxide detoxific

214 Talin and kindlin are cytoplasmic proteins that bind to integrin and modulate

215 (AtEH1/Pan1 and AtEH2/Pan1) which, although cytoplasmic proteins, are not associated with the hexame

216 Annexins are abundant cytoplasmic proteins, which bind to membranes that expos

217 We found that three cytoplasmic proteins-ZC3H12A, ZC3H12B, and ZC3H12C-bound

218 terotrimeric G proteins is modulated by many cytoplasmic proteins.

219 data shows that combining extracellular and cytoplasmic proximal tagging with a biophysical binding

220 Furthermore, decreases in nuclear but not cytoplasmic Pten levels associated with a reduction in e

221 epressive regulatory role, DDX3 localized to cytoplasmic puncta with SG marker PABP1 in CRPC.

222 elevate Dishevelled levels, it forms its own cytoplasmic puncta, but these do not recruit Axin.

223 tor NPR1 resides in either the nucleus or in cytoplasmic puncta, depending on levels of the plant hor

224 temperature alters the coupling between the cytoplasmic RCK domains and the pore domain.

225 st splitting algorithm and achieved reliable cytoplasmic reconstitution of functional diphtheria toxi

226 In doing so the cytoplasmic redox ratio becomes progressively smaller, t

227 angstrom resolution crystal structure of the cytoplasmic region of RPTPalpha, encompassing D1 and D2,

228 abelling, we investigate the response of the cytoplasmic region of transmembrane helices 6 and 7 of t

229 ng partners by tagging the extracellular and cytoplasmic regions of a "bait" protein with BioID bioti

230 structural changes in the transmembrane and cytoplasmic regions of CD3 subunits.

231 the best-characterized members of a group of cytoplasmic regulators that contain a Galpha-binding and

232 tions that partially truncate its C-terminal cytoplasmic regulatory domain impair NHE6 activity and e

233 gnificant cytosolic compaction and extensive cytoplasmic reorganization, as well as the emergence of

234 rior side of the zygotes in a later phase of cytoplasmic reorganization, before the first cell divisi

235 pathy and decreased ATP that causes elevated cytoplasmic resting (diastolic) Ca(2+) concentration and

236 These CSCs carried mutations within the cytoplasmic retention domain of HDAC6, stop/gain inserti

237 llular photoactivation of Rac1, diffusion of cytoplasmic rheological tracers at a volumetric rate of

238 5S rRNA is an indispensable component of cytoplasmic ribosomes in all species.

239 ptides encoded in nuclear DNA, translated on cytoplasmic ribosomes, and imported into mitochondria.

240 adjuvant PUUC, targeting endosomal TLR7s and cytoplasmic RLRs respectively, when delivered together i

241 We here show that ZC3H5 is an essential cytoplasmic RNA-binding protein.

242 asmic shuttling protein with well-documented cytoplasmic roles as a modulator of ATP-dependent DEAD-b

243 Replacing NaCl by KGlu, the primary cytoplasmic salt in E. coli, results in a decrease of th

244 strong agonist-evoked calcium activation and cytoplasmic secretion into CSF.

245 esearch have demonstrated critical roles for cytoplasmic sensors and inflammasomes during Leishmania

246 ecognized signal transduction system whereby cytoplasmic sentinel lectins detect membrane damage lead

247 This is associated with cytoplasmic sequestration of TFEB, preventing induction

248 the pathway negatively regulates YAP through cytoplasmic sequestration.

249 telomerase RNAs undergo one round of nucleo-cytoplasmic shuttling.

250 Accordingly, MdfA should open at the cytoplasmic side and/or laterally toward the membrane to

251 jugated to the disaccharide trehalose on the cytoplasmic side of the bacterial cell membrane.

252 ith ER bound protein FNDC3A to reside in the cytoplasmic side of the ER.

253 s translocated from the extracellular to the cytoplasmic side of the membrane, is rate limiting to tr

254 rmation in the membrane, particularly on the cytoplasmic side, where autoacylation occurs.

255 orter IrtAB(4), which features an additional cytoplasmic siderophore interaction domain(5).

256 ulator of interferon genes (STING) acts as a cytoplasmic signaling hub of innate immunity that is act

257 xon growth and guidance is understanding how cytoplasmic signaling modulates the cytoskeleton to prod

258 xon growth and guidance is to understand how cytoplasmic signaling modulates the cytoskeleton to prod

259 terminus of Slack channels binds a number of cytoplasmic signaling proteins.

260 bola virus (EBOV) inclusion bodies (IBs) are cytoplasmic sites of nucleocapsid formation and RNA repl

261 domain.IMPORTANCE Inclusion bodies (IBs) are cytoplasmic sites of RNA synthesis for a variety of nega

262 mber of micronuclei and with the presence of cytoplasmic ssDNA, leading to the activation of the IFI1

263 ycle and maturation of telomerase includes a cytoplasmic stage.

264 anslational competence represents a decisive cytoplasmic step in the biogenesis of 40S ribosomal subu

265 Disruption of the fusome, a large cytoplasmic structure that extends through RCs and is im

266 gnals through the ubiquitination of specific cytoplasmic substrates.

267 the active VPS34CII complex is docked to the cytoplasmic surface of endosomal membranes, it phosphory

268 hored by the Nesprin homologue Msp300 at the cytoplasmic surface of the nucleus.

269 olled by the binding of CheY proteins to the cytoplasmic switch complex of the flagellar motor, resul

270 relevant cell lines.IMPORTANCE The HIV-1 Env cytoplasmic tail (CT) is required for efficient Env inco

271 including the transmembrane domain (TMD) and cytoplasmic tail (CT), can reshape the antigenic structu

272 terestingly, this role is independent of its cytoplasmic tail and of its catalytic activity.

273 CD2 numbers and motifs in its cytoplasmic tail controlled corolla formation.

274 on of palmitoylated cysteine residues in the cytoplasmic tail decreased the efficiency of these proce

275 without replacement of its transmembrane and cytoplasmic tail domains with their counterparts from bo

276 C/T, rs2034310) of the human CD300f receptor cytoplasmic tail inhibits the protein kinase C phosphory

277 luding the cholesterol-recognition motif and cytoplasmic tail of gp41.

278 which uses ERM and ankyrin motifs within its cytoplasmic tail to bind actin, LYVE-1 displays little i

279 Although the endodomain (cytoplasmic tail) of the S2 subunit was not absolutely r

280 d by deleting the last 19 amino acids of the cytoplasmic tail.

281 rol of an evolutionarily extended N-terminal cytoplasmic tail.

282 hin motor neurons by reducing (mislocalized) cytoplasmic TDP-43, TDP-43 aggregation and cell toxicity

283 pression gradually increased and resulted in cytoplasmic TDP-43, widespread ubiquitination, and corti

284 n DsbD reduces DsbC and is itself reduced by cytoplasmic thioredoxin.

285 The requirement of TARS2, but not cytoplasmic threonyl-tRNA synthetase TARS, for this effe

286 ) or TDP-43(G348C) mice led to a decrease in cytoplasmic to nuclear ratio of human TDP-43.

287 cilitating the HCR amplification analysis of cytoplasmic TR.

288 tion, increased protein turnover, and nucleo-cytoplasmic trafficking.

289 To characterize the nuclear and cytoplasmic transcriptomes during brain development, we

290 We also observed that this cytoplasmic translocation is required for full activatio

291 cer progression by regulating the nuclear to cytoplasmic translocation of their effector, WDR26, via

292 While the implication of cytoplasmic transport in d-Ser toxicity was unsurprising

293 hesion links are stabilized at the tips by a cytoplasmic tripartite module containing the scaffolds U

294 investigated the activation of Src family of cytoplasmic tyrosine kinases (SFKs) and two SFK substrat

295 pertrophied contractile vacuoles and intense cytoplasmic vacuolization, possibly resulting in osmotic

296 ch all four phenolic rings are nitrated, (6) cytoplasmic vesicles in vascular endothelial cells known

297 hese proteins are involved in degradation of cytoplasmic viral and/or unspliced transcripts.

298 dverse impacts on plasma-membrane functions, cytoplasmic viscosity, protein behaviour, and other esse

299 eserve capacity to support larger functional cytoplasmic volumes in developing myofibers.

300 omyosin networks, generated by encapsulating cytoplasmic Xenopus egg extracts into cell-sized 'water-