ライフサイエンスコーパス: cytoplasmic tail

1 rol of an evolutionarily extended N-terminal cytoplasmic tail.

2 tibodies), the transmembrane domain, and the cytoplasmic tail.

3 indlin-3 through interactions with the beta3 cytoplasmic tail.

4 ated with mutant virions that lacked the Env cytoplasmic tail.

5 f tyrosine residues embedded in ITIMs of the cytoplasmic tail.

6 a and possible compensatory mutations in the cytoplasmic tail.

7 utant without the afadin-binding site in its cytoplasmic tail.

8 transmembrane region, and a short conserved cytoplasmic tail.

9 d proximal to the B30.2 domain in the BTN3A1 cytoplasmic tail.

10 smic proteins talin and kindlin to the beta3 cytoplasmic tail.

11 e pore-lining S6 helix connects to a helical cytoplasmic tail.

12 or tyrosine-based switch motifs in the NTB-A cytoplasmic tail.

13 d by deleting the last 19 amino acids of the cytoplasmic tail.

14 sical interaction between Mcc and the Vangl2 cytoplasmic tail.

15 o the parasite actomyosin system through its cytoplasmic tail.

16 l degradation owing to the truncation of its cytoplasmic tail.

17 hat cortactin binds directly to the cadherin cytoplasmic tail.

18 mains (TMDs) and a highly charged C-terminal cytoplasmic tail.

19 erved YxxO trafficking motif in the envelope cytoplasmic tail.

20 ons of two critical leucines on the receptor cytoplasmic tail.

21 lication of an HIV-1 gp41 mutant lacking the cytoplasmic tail.

22 need for signal transduction by the neurexin cytoplasmic tail.

23 s-presentation by MHC-I containing the HLA-C cytoplasmic tail.

24 F, and transmembrane domains, as well as the cytoplasmic tail.

25 se A-mediated phosphorylation of B2AR on the cytoplasmic tail.

26 th p120-catenin and beta-catenin through its cytoplasmic tail.

27 sequence in the receptor's carboxyl-terminal cytoplasmic tail.

28 ecruits Gag by a process that depends on its cytoplasmic tail.

29 kinase domain but suppressing it through its cytoplasmic tail.

30 ular switch in the amyloid precursor protein cytoplasmic tail.

31 fluenced by the presence of a truncated CD1d cytoplasmic tail.

32 e transmembrane (TM) domain and a 20-residue cytoplasmic tail.

33 anslation initiation sites in the N-terminal cytoplasmic tail.

34 le Ig domains, a transmembrane domain, and a cytoplasmic tail.

35 tes Pro(1146) for Ser in the integrin alphaM cytoplasmic tail.

36 and p120-binding domains within the cadherin cytoplasmic tail.

37 the presence of the distal region of the M2 cytoplasmic tail.

38 immediate stop codon, resulting in a shorter cytoplasmic tail.

39 ifferent binding domains within the integrin cytoplasmic tail.

40 artner of a platelet-specific alpha-integrin cytoplasmic tail.

41 tutions distinguish the Patr-AL and HLA-A*02 cytoplasmic tails.

42 is regulated by binding of proteins to their cytoplasmic tails.

43 on of motifs based on Tyr or di-Leu in their cytoplasmic tails.

44 ary complex with the Talin and beta-integrin cytoplasmic tails.

45 in-containing tyrosine phosphatases to their cytoplasmic tails.

46 er, a seven-helix transmembrane domain and a cytoplasmic tail(15).

47 noglobulin-like receptor, three domain, long cytoplasmic tail, 2 (KIR3DL2); interleukin 4 (IL4); and

48 virus M2 ion channel protein contains in its cytoplasmic tail a membrane-proximal amphipathic helix t

49 x32, the expression of cell surface-targeted cytoplasmic tail alone is sufficient to enhance the size

50 88/T789 phospho-switch in the integrin beta1 cytoplasmic tail and constitutes a novel target to modul

51 his effect is mediated by the integrin beta1 cytoplasmic tail and does not entail beta1 heterodimeriz

52 ermining talin binding to the beta3-integrin cytoplasmic tail and inducing a kink in the transmembran

53 of a clade B virus Env, which lacks only the cytoplasmic tail and is stabilized by the broadly neutra

54 that interaction between the integrin beta1 cytoplasmic tail and kindlin-2, a member of a family of

55 terestingly, this role is independent of its cytoplasmic tail and of its catalytic activity.

56 recognized regulatory capacity of the Man1b1 cytoplasmic tail and provided insight into the functiona

57 a1-integrin by restricting the motion of the cytoplasmic tail and reducing the entropic barrier for t

58 Interactions between the glycoprotein cytoplasmic tail and the matrix domain of Gag are though

59 n-2 but not polysialylated when it lacks its cytoplasmic tail and transmembrane region and is secrete

60 h intracellular interactions at the integrin cytoplasmic tails and through integrin-ligand binding.

61 in the membrane-proximal region of the GluA2 cytoplasmic tail, and suggest a distinct model for the r

62 beta-subunits are well separated with their cytoplasmic tails approximately 8 nm apart.

63 ereas the carboxyl termini, often called the cytoplasmic tails, are highly divergent.

64 In resting T cells, the CD3epsilon cytoplasmic tail associates with the plasma membrane via

65 Kindlins are integrin cytoplasmic tail binding partners and are essential for

66 we provide mechanistic insight into MT1-MMP cytoplasmic tail binding protein 1 (MTCBP-1) with respec

67 n between ADAP and 2 essential integrin-beta cytoplasmic tail-binding proteins involved in alphaIIbbe

68 of a yeast two-hybrid screen for the MT1-MMP cytoplasmic tail-binding proteins, we identify here a no

69 SYG-1 cytoplasmic tail binds to the WRC using a consensus WRC

70 not affect its binding to the integrin beta3 cytoplasmic tail, but combined biochemical and NMR analy

71 7 activation involves phosphorylation of its cytoplasmic tail by mitogen-activated protein kinase (MA

72 embrane to induce phosphorylation of the CD3 cytoplasmic tails by incompletely understood mechanisms.

73 We further show that the presence of a cytoplasmic tail (c-tail) is indispensible, and identifi

74 n-like domain, a transmembrane domain, and a cytoplasmic tail containing a YXX sorting motif.

75 ersions of their FcgammaRII by switching the cytoplasmic tails containing the ITAM/ITIM motifs, leavi

76 CD2 numbers and motifs in its cytoplasmic tail controlled corolla formation.

77 a/DRbeta dimer most other amino acids in the cytoplasmic tail could be substituted for alanine with m

78 te the effects of functional properties of F cytoplasmic tail (CT) amino acids on virus replication a

79 ry syncytial virus (HRSV) fusion (F) protein cytoplasmic tail (CT) and matrix (M) protein are key med

80 ES is mediated by an interaction between its cytoplasmic tail (CT) and N.

81 single virus assembly sites requires the Env cytoplasmic tail (CT) and the L12 residue in the matrix

82 nt study, we modified RSV F by replacing its cytoplasmic tail (CT) domain or its CT and transmembrane

83 lope glycoprotein (Env) that contains a long cytoplasmic tail (CT) harboring trafficking motifs impli

84 shows anti-inflammatory properties, and its cytoplasmic tail (CT) interacts with transcription facto

85 The GP2 cytoplasmic tail (CT) is relatively conserved among aren

86 relevant cell lines.IMPORTANCE The HIV-1 Env cytoplasmic tail (CT) is required for efficient Env inco

87 uorescently labeled wild-type constructs and cytoplasmic tail (CT) mutants.

88 Truncation of the cytoplasmic tail (CT) of Env abrogated Gag's ability to

89 The highly conserved long cytoplasmic tail (CT) of Env is required in a cell type-

90 h interactions with host cell machinery, the cytoplasmic tail (CT) of F is a likely interactive domai

91 The cytoplasmic tail (CT) of GP2 is highly conserved among a

92 extracellular domain of rabies fused to the cytoplasmic tail (CT) of gp41 and pseudotyped lentiviral

93 The cytoplasmic tail (ct) of RAGE is essential for RAGE liga

94 teractions between the uncleaved Gag and the cytoplasmic tail (CT) of the Env protein.

95 eptor (CD21=CR), a mutant lacking the entire cytoplasmic tail (CT), and a control vector (NEO) were s

96 including the transmembrane domain (TMD) and cytoplasmic tail (CT), can reshape the antigenic structu

97 s homologous gp41 envelope glycoprotein (GP) cytoplasmic tail (CT), we created chimeric RVG/HIV-1gp41

98 -muscle myosin IIA, a motor protein, via the cytoplasmic tail (CT).

99 ld be modulated through small changes in its cytoplasmic tail (CT).

100 tood but involves an interaction between Env cytoplasmic tails (CTs) and the matrix (MA) domain of th

101 vidence of an interaction between MA and the cytoplasmic tails (CTs) of Env trimers that contributes

102 irtue of an interaction with the Env protein cytoplasmic tails (CTs).

103 Mutations within the cytoplasmic tail (cytotail) of herpes simplex virus 1 (H

104 on of palmitoylated cysteine residues in the cytoplasmic tail decreased the efficiency of these proce

105 that compared with the full-length Cx32, the cytoplasmic tail-deleted Cx32 is assembled into small ga

106 ficant increase in IgM ligand binding in the cytoplasmic tail-deletion mutant, 2) enhanced cap format

107 tsO45 with either the native G tail (G) or a cytoplasmic tail derived from the chicken AE1-4 anion ex

108 Deletion or replacement of the FcRn cytoplasmic tail does not prevent diversion of trafficki

109 amino acids (+3 leucine) or by deleting the cytoplasmic tail domain (CTD) in the +1 leucine backgrou

110 In addition, the P2 cytoplasmic tail domain mediated the constitutive intera

111 ecombinant influenza B virus lacking the BHA cytoplasmic tail domain.

112 However, when the cytoplasmic tail domains (CTDs) in the Env constructs we

113 without replacement of its transmembrane and cytoplasmic tail domains with their counterparts from bo

114 mutation that truncated most of the tetherin cytoplasmic tail early in the Feliformia lineage (19 of

115 hat are linked via the interaction of the E2 cytoplasmic tail/endodomain with the capsid protein.

116 a membrane-bound Env trimer with a truncated cytoplasmic tail (EnvDeltaCT).

117 There are also 7 non-constitutive cytoplasmic tail exons that can either be included or sk

118 istically, P1146S substitution in the alphaM cytoplasmic tail generates a noncanonical 14-3-3zeta bin

119 ot PHV, harbor elements in their 142-residue cytoplasmic tails (GnTs) that inhibit RIG-I/MAVS/TBK1-TR

120 Truncation of their cytoplasmic tail has little effect on membrane fusion, b

121 The beta1 cytoplasmic tail has two NPxY motifs that mediate functi

122 plasmic tail of Vpu, specifically within the cytoplasmic tail hinge region, were required for modulat

123 essing the membrane-bound ADAM15 without its cytoplasmic tail, however, lost this anti-apoptotic prop

124 Deletion of the Env cytoplasmic tail improved the efficiency with which the

125 These results demonstrate the role of the F cytoplasmic tail in accumulation of structural component

126 To understand the role of this cytoplasmic tail in infectious virus production, we used

127 ic cleavage of the murine leukemia virus Env cytoplasmic tail in pseudotyped virions.

128 ete conformational changes in the C-terminal cytoplasmic tail in response to changes in cytoplasmic C

129 onstrated proteoforms of ADAM8 that lack the cytoplasmic tail in the supernatant.

130 Moreover, the beta1 cytoplasmic tail, in the context of the adjacent transme

131 tifs (FxNPxY or HIC) encoded within the LDLR cytoplasmic tail, indicating an additional internalizati

132 idues where replaced with those of the beta1 cytoplasmic tail induced only small chemical shift pertu

133 ed that a dileucine-like motif in the DRbeta cytoplasmic tail influences the efficiency of co-localiz

134 C/T, rs2034310) of the human CD300f receptor cytoplasmic tail inhibits the protein kinase C phosphory

135 se results suggest that PC1, via its cleaved cytoplasmic tail, integrates signaling inputs from EGFR

136 The cytoplasmic tail is apparently crucial for internalizati

137 The short cytoplasmic tail is lacking in any known signaling motif

138 fected by the origin of F, suggesting that F cytoplasmic tail is not involved in intracellular moveme

139 splay a number of unique features, including cytoplasmic tails lacking characteristic SLAMF signaling

140 he viral transmembrane envelope glycoprotein cytoplasmic tail leads in pig-tailed macaques to a uniqu

141 al regulation of the Thr(567) in the MT1-MMP cytoplasmic tail may function as a regulatory mechanism

142 We demonstrate that m154 uses its cytoplasmic tail motif, DD, to interfere with the adapto

143 Knockin mice with CD28 cytoplasmic tail mutations that abrogate Vav signaling (

144 TgAMA1 cytoplasmic tail mutations that disrupt ALD binding in v

145 ture, an S6 activation gate position and the cytoplasmic tail "neck", are central to BacNaV gating.

146 ding domains for signaling proteins in their cytoplasmic tails, nonetheless also transduce signals to

147 ith a knockin mutation that ablates the NRP1 cytoplasmic tail (Nrp1(cyto)) have normal angiogenesis b

148 ows the importance of single residues in the cytoplasmic tail of a Golgi-resident protein for localiz

149 red reactions whereby an enzyme bound to the cytoplasmic tail of a receptor catalyzes reactions on su

150 dback by blocking the phosphorylation of the cytoplasmic tail of Ackr3 also results in less direction

151 ng partner, p120-catenin (p120ctn), with the cytoplasmic tail of apical mucin-1 (MUC1-CT) represent i

152 ion of the DXXLL-motif sequence DISLL in the cytoplasmic tail of BACE1.

153 The cytoplasmic tail of beta-integrin (PAT-3) is associated

154 tinin competes with talin for binding to the cytoplasmic tail of beta3-integrin, whereas it cooperate

155 Furthermore, p120-catenin binds to the cytoplasmic tail of cadherin and stabilizes it at the pl

156 and cargo-tethering protein, recognized the cytoplasmic tail of CD147 to help sort it and CD98 into

157 r of beta2 integrins that interacts with the cytoplasmic tail of CD18 and is crucial for induction of

158 Two sites within the cytoplasmic tail of CD28, a YMNM sequence that recruits

159 ual CD44 fragment, liberating the C-terminal cytoplasmic tail of CD44.

160 n adherens junctions, beta-catenin links the cytoplasmic tail of classical cadherins to the F-actin-b

161 terminus to active GTP-Rab8, as well as the cytoplasmic tail of CTLA-4.

162 The C-terminal cytoplasmic tail of Ctr1 is a 13-residue peptide harbori

163 Our results suggest that the cytoplasmic tail of Cx32 is not required to initiate the

164 Our findings suggest that the cytoplasmic tail of Cx32 may be involved in regulating t

165 We have explored the role of the cytoplasmic tail of Cx32, a Cx expressed in polarized an

166 In epithelial cells, the cytoplasmic tail of E-cadherin forms a dynamic complex w

167 ith the retrieval mutant, replacement of the cytoplasmic tail of E3/19K allowed only limited transpor

168 Interestingly, the cytoplasmic tail of E3/49K contains two potential sortin

169 determined by distinct motifs present in the cytoplasmic tail of each cargo, with Wls using tandem Ph

170 x (MA) domain of the Gag polyprotein and the cytoplasmic tail of Env are central players in the proce

171 mbly and the matrix domain accommodating the cytoplasmic tail of Env in the Gag lattice.

172 y distinct but complementary roles, with the cytoplasmic tail of Env responsible for directing Env to

173 itionally, we found that truncating the long cytoplasmic tail of Env restores incorporation of Env in

174 e rearrangements result in truncation of the cytoplasmic tail of EPOR at residues similar to those mu

175 of suspected gamma-COP-binding motifs in the cytoplasmic tail of ERManI was sufficient to disrupt the

176 The absence of peptides from the C-terminal cytoplasmic tail of fibrocystin implies a cleavage event

177 luding the cholesterol-recognition motif and cytoplasmic tail of gp41.

178 Whereas the two cysteines in the cytoplasmic tail of HA contain only palmitate, stearate

179 a lattice capable of accommodating the long cytoplasmic tail of HIV-1 Env; in the absence of MA trim

180 Third, deletion of the cytoplasmic tail of HIV-1 gp41 dramatically enhanced the

181 well as tail swap experiments exchanging the cytoplasmic tail of HLA-A2 with that of HLA-E, demonstra

182 ulated HLA-E surface levels and targeted the cytoplasmic tail of HLA-E.

183 The C-terminal cytoplasmic tail of human PC2 (HPC2 Cterm) is important

184 We show that the cytoplasmic tail of IAV M2 interacts directly with the e

185 The highly conserved cytoplasmic tail of influenza virus glycoprotein hemaggl

186 rtilin, as retromer can directly bind to the cytoplasmic tail of IRAP.

187 inflammatory conditions, we report that the cytoplasmic tail of JAM-A is tyrosine phosphorylated (p-

188 se mutation from methionine to lysine in the cytoplasmic tail of Kcc1 impairs phosphorylation of adja

189 Proteins binding to the cytoplasmic tail of L-selectin regulate L-selectin funct

190 put is dependent on this interaction and the cytoplasmic tail of L-selectin.

191 ic calcium-binding protein calmodulin to the cytoplasmic tail of L-selectin.

192 a premature stop codon deleting most of the cytoplasmic tail of LAT, including the critical tyrosine

193 A, and recovery from each, we found that the cytoplasmic tail of M6PR causes the recruitment of AP-1

194 Herein we report that the intracellular cytoplasmic tail of Met has evolved to harbor a tandem p

195 p11 directly binds to the cytoplasmic tail of metabotropic glutamate receptor 5 (m

196 an amino acid signal motif (LPYS) within the cytoplasmic tail of MNS3 that acts as a specific Golgi r

197 es show that islet formation is based on the cytoplasmic tail of MT1-MMP and its ability to bind the

198 Accumulating evidence shows that the cytoplasmic tail of MT1-MMP is subjected to phosphorylat

199 neurons with and without a peptide from the cytoplasmic tail of NaVbeta4 (the beta4 peptide), which

200 eported that tyrosine phosphorylation of the cytoplasmic tail of nephrin facilitates recruitment of N

201 Replacing the cytoplasmic tail of Patr-AL with that of HLA-A*02 increa

202 n which parts of the N and C terminus of the cytoplasmic tail of PC7 were deleted, and chimeric prote

203 The cytoplasmic tail of PD-1 contains an immunoreceptor tyro

204 that C-terminus of c-Cbl interacted with the cytoplasmic tail of PD-1.

205 In resting platelets, the cytoplasmic tail of PEAR1 was found complexed to c-Src a

206 ovel, direct binding interaction between the cytoplasmic tail of podocalyxin and the large GTPase dyn

207 The cytoplasmic tail of POMGnT1 was found to be critical for

208 ng tyrosine phosphatase 2 phosphatase to the cytoplasmic tail of programmed death-1.

209 , replacing their cytoplasmic tails with the cytoplasmic tail of PSGL-1 significantly enhanced their

210 We further show that the cytoplasmic tail of rat ADAM17 contains a conserved seri

211 The cytoplasmic tail of Rbd2 appears to modulate PtdIns(4,5)

212 etic and biochemical studies showed that the cytoplasmic tail of Rbd2 binds directly to PtdIns(4,5)P2

213 GIV is recruited to the cytoplasmic tail of receptors upon stimulation, but the

214 onfirm that a linear sequence located in the cytoplasmic tail of Robo2 (residues 991-1070) interfaces

215 r lysosomal anchor complex Ragulator and the cytoplasmic tail of SLC38A9 in the pre- and post-GTP hyd

216 ith the first luminal loop of Glut4, and the cytoplasmic tail of sortilin binds to retromer.

217 on of a single lysine residue present in the cytoplasmic tail of the alpha chain, DMalpha.

218 ons, Lys4Gln and Ser15Tyr, in the N-terminal cytoplasmic tail of the alpha subunit of phosphotransfer

219 a the evolutionarily conserved lysine in the cytoplasmic tail of the beta chain in dendritic cells (D

220 osine kinase c-Src in platelets binds to the cytoplasmic tail of the beta3 integrin subunit via its S

221 Here we reveal that the cytoplasmic tail of the GABABR2 subunit binds directly t

222 interactions between Gag's MA domain and the cytoplasmic tail of the gp41 subunit of Env (gp41CT).

223 ract with both the small GTPase Rap1 and the cytoplasmic tail of the Heart of glass (HEG1) membrane a

224 Here we show that the cytoplasmic tail of the human lysosomal solute carrier f

225 s that engage two distinct epitopes from the cytoplasmic tail of the ligand Jagged1, one in the intra

226 esenting cells through ubiquitination of the cytoplasmic tail of the mMHCII beta chain.

227 erved motifs YxxPhi and/or KxHxx/KKxx in the cytoplasmic tail of the S protein.

228 e that the matrix (MA) domain of Gag and the cytoplasmic tail of the transmembrane glycoprotein gp41

229 Furthermore, the cytoplasmic tail of this Eph kinase regulates initial pl

230 Second, mutating Y731 in the cytoplasmic tail of VE-cadherin, known to selectively af

231 identified 4 amino acid substitutions in the cytoplasmic tail of viral envelope glycoprotein gp41 of

232 whereby Trp-76 anchors the C terminus of the cytoplasmic tail of Vpu to the plasma membrane, enabling

233 We found that features in the cytoplasmic tail of Vpu, specifically within the cytopla

234 ize interactions between 14-3-3-zeta and the cytoplasmic tails of alpha4, beta1, beta2 and beta3 inte

235 oplasmic domain-associated protein-1) to the cytoplasmic tails of beta1 integrins inhibits integrin a

236 o found that polybasic motifs present in the cytoplasmic tails of CD43 and CD44 also promote their co

237 The cytoplasmic tails of human and simian immunodeficiency v

238 ere it directly binds NPX(Y/F) motifs in the cytoplasmic tails of its target receptors to mediate the

239 Ms) are signaling domains located within the cytoplasmic tails of many transmembrane receptors and as

240 3 ligases that promote ubiquitination of the cytoplasmic tails of Notch ligands.

241 vide evidence for direct binding between the cytoplasmic tails of receptors and the WAVE complex, a r

242 ITAMs also have been identified in the cytoplasmic tails of some enveloped virus glycoproteins.

243 Signaling within the cell modifies the cytoplasmic tails of substrates, a step important in sta

244 lation of conserved tyrosine residues in the cytoplasmic tails of tetherin dimers.

245 by binding adaptor proteins to the flexible cytoplasmic tails of the alpha- and beta-integrin subuni

246 athway in which the Ycks prime a site on the cytoplasmic tails of the glucose sensors to promote bind

247 and Tyk2 phosphorylation, which bind to the cytoplasmic tails of the IL-4Ralpha/IL-13Ralpha1 complex

248 in which polybasic sequences present in the cytoplasmic tails of the membrane proteins and in Gag ar

249 ayers on the membrane association of the CD3 cytoplasmic tails of the T-cell receptors.

250 e (ALD) provides a critical link between the cytoplasmic tails of transmembrane adhesins and the acti

251 ors that bind to short, linear motifs in the cytoplasmic tails of transmembrane protein cargos and se

252 Although the endodomain (cytoplasmic tail) of the S2 subunit was not absolutely r

253 potential ubiquitin conjugation sites in the cytoplasmic tail or Lys residues in the ectodomain.

254 eolytic fragment of PC1 corresponding to the cytoplasmic tail, PC1-p30, is overexpressed in ADPKD.

255 We used L-selectin cytoplasmic tail peptide pulldown assays combined with h

256 Further analysis indicated that the F cytoplasmic tail plays a critical role in cell surface e

257 dition, TNS4 interaction with beta1-integrin cytoplasmic tail positively regulates beta1-integrin sta

258 he N terminus of the surface subunit and the cytoplasmic tail R peptide.

259 Mutations in the distal cytoplasmic tail region of M2, and in particular a tyros

260 nomodulatory fusion proteins (IFPs) with the cytoplasmic tail replaced by the signaling domain of the

261 paB activation, indicating that the tetherin cytoplasmic tail resembles the hemi-immunoreceptor tyros

262 proximal and distal NPxY motifs of the beta1 cytoplasmic tail, respectively.

263 iciency virus (SIV) SIVmac239 envelope (Env) cytoplasmic tail resulted in a virus (DeltaGY) that exhi

264 ch expresses a chimeric hPIV1 F with the SeV cytoplasmic tail sequence grew similar to wt SeV or rSeV

265 re highly similar in structure, however, the cytoplasmic tail sequences of the envelope glycoproteins

266 Truncation of the NiV-F cytoplasmic tail (T5F) alone, combined with full-length

267 MICA/B molecules and a dilysine motif in the cytoplasmic tail that confers retrieval from the Golgi a

268 scence response, we mapped the region in its cytoplasmic tail that controls signaling.

269 er, there are 5 tyrosine residues within the cytoplasmic tail that could potentially mediate TbetaRII

270 dileucine sorting signal encoded within the cytoplasmic tail that directs Notch to the limiting memb

271 ons to the F protein transmembrane domain or cytoplasmic tail that disrupted endocytic trafficking le

272 tion required arginine residues in the ICOSL cytoplasmic tail that recruited the adaptor protein RACK

273 vide evidence for a motif within the SorCS1c cytoplasmic tail that, when manipulated, results in pert

274 brane-proximal segment in the integrin beta1 cytoplasmic tail, that Arg phosphorylates the membrane-p

275 mbrane by a mechanism requiring the receptor cytoplasmic tail, the intraflagellar transport complex-B

276 in 3 (GGA3) interacts directly with the TrkA cytoplasmic tail through an internal DXXLL motif and med

277 chimeric protein with its transmembrane and cytoplasmic tail (TMCT) domains substituted with those o

278 chimeric form in which its transmembrane and cytoplasmic tail (TMCT) domains were replaced with those

279 IT1 with ICAP1 and ICAP1 with integrin beta1 cytoplasmic tail to 2.54 and 3.0 A resolution (the resol

280 which uses ERM and ankyrin motifs within its cytoplasmic tail to bind actin, LYVE-1 displays little i

281 However, transfer of the human tetherin cytoplasmic tail to mouse tetherin restored restriction

282 et al. elucidate how the binding of the DSG1 cytoplasmic tail to the scaffolding protein Erbin decrea

283 ur results show how Pxn binding to the CD103 cytoplasmic tail triggers alphaEbeta7 integrin outside-i

284 mutation in the ezrin binding site, or with cytoplasmic tail-truncated CD44.

285 presentation by MHC-I molecules containing a cytoplasmic tail tyrosine signal (murine MHC-I molecules

286 Phosphorylation within CD300f cytoplasmic tail tyrosine-based motifs initiates signals

287 K stimulation, SGEF is recruited to the Fn14 cytoplasmic tail via TRAF2.

288 h was an unexpected finding because its 7-aa cytoplasmic tail was assumed to be inert.

289 revealed, moreover, that the entire neurexin cytoplasmic tail was dispensable for heterologous synaps

290 gH chimera in which the gH transmembrane and cytoplasmic tail were replaced with that of human CD4 pr

291 C-I molecules containing a human MHC-I HLA-C cytoplasmic tail, which does not contain a tyrosine sign

292 st 12 amino acids of the longer (L-tetherin) cytoplasmic tail, which includes a tyrosine motif that a

293 ane proteins, the binding of adaptors to its cytoplasmic tail, which is 47 residues long and contains

294 ary structure of melanopsin indicates a long cytoplasmic tail with many potential phosphorylation sit

295 tes neurotransmission via interaction of its cytoplasmic tail with the synaptic release machinery.

296 se inclusion or skipping generates different cytoplasmic tails with distinct functions.

297 However, replacing their cytoplasmic tails with the cytoplasmic tail of PSGL-1 si

298 ified two alternatively spliced exons in the cytoplasmic tail, with transmembrane domains in exon var

299 Also, mutations of the beta3 cytoplasmic tail (Y747F and Y759F) that block beta3 tyro

300 e-based motif YEVF or YEAF) and KVHVQ at the cytoplasmic tail, yet their functions have not been full