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1 with or without vemurafenib (960 mg PO twice daily).
2 n switched to 50 mg film-coated tablets once daily.
3 s, with 52 (46%) patients experiencing these daily.
4 ned from each eye ranged from 1 daily to 277 daily.
5 ents received 5 mg of folic acid orally once daily.
6 ontrol) or 20, 40, or 80 mg telmisartan once daily.
7 uested to obtain at least 4 IOP measurements daily.
8 f lens epithelial cells was photo-documented daily.
9 to <12 years received sofosbuvir 200 mg once daily.
10 t Method and Sour Seven) were completed once daily.
11 ea/ocean, and not changing the kitchen towel daily.
12 abacavir 600 mg, and lamivudine 300 mg once daily.
13 ose of 100 mg/m(2) (maximum of 100 mg) twice daily.
14 d TDF/FTC dosing as (1) "perfect" adherence (daily); (2) "moderate" adherence (4 doses/week); or (3)
15 g once daily -3.8 (0.2; p=0.039), 60 mg once daily -3.6 (0.2; p=0.039), 30 mg twice daily -4.2 (0.4;
16 g once daily -4.0 (0.3; p=0.024), 30 mg once daily -3.8 (0.2; p=0.039), 60 mg once daily -3.6 (0.2; p
17 etection, increasing to 8.3% (67%) for twice-daily 30-second ECGs during 14 days and to 11% (68%), 13
18 ne days versus placebo: atogepant 10 mg once daily -4.0 (0.3; p=0.024), 30 mg once daily -3.8 (0.2; p
20 once daily -3.6 (0.2; p=0.039), 30 mg twice daily -4.2 (0.4; p=0.0034), and 60 mg twice daily -4.1 (
21 tion 48) demonstrated noninferiority of once-daily 60 mg (30 mg dose-reduced) edoxaban compared with
23 30% decrease in the weekly average of worst daily abdominal pain compared with baseline in at least
24 gistic mixed-effects model was used to model daily abstinence from alcohol over the 21 days after ket
25 less interference of neurologic symptoms in daily activities (P = .008) and fewer cognitive symptoms
26 e (40% versus 25%; P=0.019), and independent daily activities (taking a shower: 53% versus 38%, P=0.0
33 on-treatment drug use (P >.99), or imperfect daily adherence (P = .35) but was significantly associat
34 ose who experienced significant dry eye (ie, daily/almost daily dry eye) more often agreed that livin
35 53%) experienced severe dry eye (ie, dry eye daily/almost daily with major impact on their life).
36 73.5% of patients receiving BOT 0.5 mg twice daily and 75% receiving BOT 1.0 mg twice daily were in p
39 g (ADAPT) Study evaluated the feasibility of daily and nondaily human immunodeficiency virus (HIV) pr
40 ches around the world continuously adjust to daily and seasonal changes in wave and tide conditions,
42 Evaluable patients assigned to the twice-daily and thrice-daily regimens showed substantially red
43 , to adults mostly at a dose of 100 mg twice daily, and to paediatric patients mostly at a dose of 10
45 ion of dinitrogen plays an important role in daily anthropogenic life, and the processes by which thi
46 ues for sTXB2 (ng/mL) compared with the once-daily arm: 4 (2.1-6.7; n = 79), 2.5 (1.4-5.65, n = 79),
48 othiazide, and 10 mg of ramipril) or placebo daily, aspirin (75 mg) or placebo daily, and vitamin D o
51 was not a significant source of variation in daily B-cell levels or any CD4+ functional subset, it ac
53 experience thousands of distinct events on a daily basis, relatively few are committed to memory.
56 times daily [QID, high-dose] or CsA CE twice daily [BID, low-dose] + vehicle BID) and vehicle patient
58 the modified Arrhenius equation on modelled daily carbon gain causes a meaningful deviation of c. 18
59 istically significant difference in the mean daily case growth rate before versus after implementatio
62 To address this problem we use downscaled daily climate predictions from seven GCMs to run a conti
64 omarkers in FFPE samples to meet the need of daily clinical practice, especially for local laboratori
67 aphy, mouth level exposure (MLE) and average daily consumption (ADC) relating to two commercially ava
73 monstrated high adherence to once- and twice-daily DAA therapy among people with recent IDU or curren
74 ticipants self-collected mid-turbinate swabs daily (days 1 to 14) for SARS-CoV-2 polymerase chain rea
78 f these products provide up to 20-30% of the daily dietary reference intake of essential trace minera
80 d fluid restriction of <1000 ml/24 h, a once-daily dose of oral empagliflozin or placebo for 4 days.
81 showed a significant reduction in the lowest daily dose of oral prednisolone throughout the entire tr
83 le administration, and again on Day 10 after daily doses of either 4 mg (Cohorts 1 and 2), or 1 mg (C
84 ervention group received significantly lower daily doses of everolimus and nonsignificantly lower dos
85 ng (OR, 2.18 [95% CI, 1.01-4.70]), and twice-daily dosing (OR, 2.81 [95% CI, 1.47-5.36]) were associa
88 in terms of clinical course, involved drugs, daily drug dose, latency periods, test results of skin t
89 ienced significant dry eye (ie, daily/almost daily dry eye) more often agreed that living with Sjogre
90 ng wastewater from several FPIs, two months' daily effluent samples were collected and measured using
91 asthma, or allergic rhinitis should not use daily emollients to try and prevent eczema in their newb
95 stood as a means for organisms to anticipate daily environmental changes, circadian rhythms are also
96 f principle model successfully predicted the daily evolution of AD severity scores at an individual l
100 >=37 weeks gestational age) or 4 mg/kg twice daily for 1 week and 6 mg/kg twice daily thereafter for
102 00 days (n = 100) or valganciclovir, 900 mg, daily for 100 days as antiviral prophylaxis (n = 105).
103 nts were treated with 4 mg baricitinib twice daily for 2 days, followed by 4 mg per day for the remai
104 assigned to hydroxychloroquine (400 mg twice daily for 2 doses, then 200 mg twice daily for 8 doses)
105 pin, isoniazid, ethambutol, and pyrazinamide daily for 2 months, followed by rifampin and isoniazid d
106 ersus matching placebo was taken orally once daily for 26 weeks followed by nilotinib 300 mg versus p
109 with 1 dose of TMP-SMZ (160 mg/800 mg) twice daily for 45 days, and all lesions healed after this tre
111 o receive 1 of the following 3 interventions daily for 5 wk: low-nitrate vegetables + placebo pills,
113 mized to receive isoniazid 5, 10 or 15 mg/kg daily for 7 days (inhA group), and controls with drug-se
118 oroquine (600 mg twice on day 1, then 400 mg daily for a median of 5 days); 45.8% of the patients wer
120 ecommended aspirin regimen of 75 to 100 once daily for cardiovascular prophylaxis appears to be large
123 itors plus nevirapine dosed at 6 mg/kg twice daily for term neonates (>=37 weeks gestational age) or
124 nded supply of lozenges to be consumed twice daily for the following 42 days containing either the pr
126 external APBI using IMRT technique in 5 once-daily fractions is low and not different from that after
127 rium infantis (LB) to pregnant C57/BL6J mice daily from E16 to weaning, significantly suppressed post
128 and parent-reported interference of pain in daily functioning (38% and 50%, respectively) and overal
129 eeks, tended to increase the overall average daily gain, delayed the FI and BW depression for ~ 2 wee
130 mpaired thermoregulation and lowered average daily gains (ADG) result when livestock graze toxic endo
131 to isolate secular tectonic motions from the daily GNSS time series to show that the 2010 Maule, Chil
132 ates, we conclude that face masks reduce the daily growth rate of reported infections by around 47%.
135 Many parts of the visuomotor system guide daily hand actions, like reaching for and grasping objec
136 tion is associated with an increased risk of daily hospital admission for depression in the general u
138 ce in average total hospital charges, though daily hospital charges were significantly lower for pati
140 in fasted adults on dolutegravir 50 mg once-daily; in children weighing 25 kg to less than 30 kg tak
141 X-M) abundance during treatment (21% and 10% daily increase, respectively), while treatment with mero
142 1 followed by 100 mg on days 2-10 in single daily infusions) or the same volume of placebo infusions
146 ree long-term datasets on bird reproduction, daily insect availability, and weather, we investigated
148 -weekly insulin icodec as compared with once-daily insulin glargine U100 in patients who had not prev
151 A subset of women (IDEALplus) also completed daily journals and a body fat assessment via dual-energy
152 Polymers are ubiquitously present in our daily life because they can meet a wide range of needs a
153 nts who engaged in a larger number of CTs in daily life had lower connectivity in the posterior tempo
154 Occurrence, risk factors, and impact on daily life of chronic pain after critical illness have n
156 and assessment of functional capacity during daily life should be performed prior to noncardiac surge
157 itive function, physical function, and basic daily life skills are assessed at 3 months and beyond 1
163 e key themes were identified: (i) individual/daily lifestyle considerations, (ii) patient involvement
164 Many organisms are experiencing changing daily light regimes due to latitudinal range shifts driv
165 odds of impaired instrumental activities of daily living (95% CI: 1.6-6.3) compared to those reporti
166 ces) that quantify mobility in unsupervised, daily living environments are emerging as complementary
167 ty, functional independence in activities of daily living, excellent functional outcome (mRS 0-1), an
169 PM(2.5) was positively correlated with O(3), daily maximum and minimum temperature, and negatively co
171 onstrate that male elephants increased their daily mean speed and range size with age and in musth.
173 d carbon fluxes is typically higher on fine (daily-monthly) timescales and reduces on longer (seasona
175 receive 960 mg of oral co-trimoxazole twice daily (n = 170) or matched placebo (n = 172) for between
182 tib 400 mg or matching placebo, orally twice daily on an intermittent weekly schedule of 4 days on an
183 2 h and oral capecitabine 1000 mg/m(2) twice daily on days 1-14 repeated every 3 weeks (regimen two).
184 e 2016 survey, spending more than 60 minutes daily on electronic devices was associated significantly
188 g (aHR, 4.00 [95% CI, 3.62-4.41]; P < .001), daily or more frequent injection (aHR, 1.45 [95% CI, 1.0
189 mly assigned 1:1 to empagliflozin 10 mg once daily or placebo, stratified by age (<65 and >=65 years)
192 us enoxaparin 4,000 international units once daily) or high regimen thromboprophylaxis (i.e. subcutan
194 ither fostemsavir (at a dose of 600 mg twice daily) or placebo to their failing regimen for 8 days, f
195 omized 2:1 to olaparib tablets (300 mg twice daily) or single-agent chemotherapy TPC (21-day cycles o
198 VKAs with target INR 2-3, rivaroxaban 10 mg daily, or rivaroxaban 10 mg daily plus vitamin K2 2000 u
199 ide 25 mg and emtricitabine 200 mg, and once-daily oral dolutegravir 50 mg; once-daily oral fixed-dos
200 te 300 mg and emtricitabine 200 mg, and once-daily oral dolutegravir 50 mg; or once-daily oral fixed-
201 once-daily oral dolutegravir 50 mg; or once-daily oral fixed-dose combination of tenofovir disoproxi
202 Participants were randomly assigned to once-daily oral fixed-dose combination tenofovir alafenamide
203 and once-daily oral dolutegravir 50 mg; once-daily oral fixed-dose combination tenofovir disoproxil f
204 r humans that may be superior in efficacy to daily oral TLZ and would be useful for treatment of PARP
205 II or III are randomized 1:1 to receive once-daily, oral mavacamten, or matching placebo for 30 weeks
208 ation was used to achieve pulmonary delivery daily over 10 days to M. tuberculosis infected mice for
210 of olaparib tablet monotherapy (300 mg twice daily) over chemotherapy treatment of physician's choice
212 as used to determine trends in postoperative daily physical activity among patients with and without
215 e ruxolitinib orally, starting at 5 mg twice daily plus corticosteroids, until treatment failure, una
216 ial comparing dabrafenib 150 mg orally twice daily plus trametinib 2 mg orally once daily versus two
217 ivaroxaban 10 mg daily, or rivaroxaban 10 mg daily plus vitamin K2 2000 ug thrice weekly during 18 mo
218 (180-mg loading dose followed by 90 mg twice daily) plus aspirin (300 to 325 mg on the first day foll
219 his work presents results from more than 300 daily PM(10) and further size-resolved atmospheric PM sa
221 he IBD Disk, a visual tool easily useable in daily practice to assess disability in IBD patients.
225 time-series of 2324 in situ measurements of daily predawn and midday Psi, the temporal variability o
226 primary exposures of interest were number of daily prescribed medications (1-2, 3-4, 5-6, 7-8, 9-10,
229 ed on their original regimen (CsA CE 4 times daily [QID, high-dose] or CsA CE twice daily [BID, low-d
233 the 9-wk follow-up period, patients recorded daily ratings of facial pain intensity and duration; the
235 ients assigned to the twice-daily and thrice-daily regimens showed substantially reduced interindivid
237 e juvenile host matures, it develops complex daily rhythms characterized by profound changes in the a
248 lignment' between their circadian system and daily sleep-wake behaviors, with negative health consequ
253 ive sample of US adults, a greater number of daily steps was significantly associated with lower all-
254 -controlled, multicentre trial compared once-daily subcutaneous administration of vosoritide with pla
255 fatigue and lower satisfaction with time for daily tasks and family/social life, whereas working 12-h
257 cant inverse association between the maximum daily temperature and the rate of cases at 5 days (IRR,
260 ctions differently as DTW results in greater daily temperature variation and moves organisms nearer t
265 enic acid), every 30 minutes: 20%-30%-50% of daily therapeutic dose, for the moderate absorption grou
266 /kg twice daily for 1 week and 6 mg/kg twice daily thereafter for preterm neonates (34 to <37 weeks g
267 acebo) and fatigue (1% [1/93] for 10 mg once daily to 10% [9/91] for 60 mg twice daily vs 3% [6/186]
268 were nausea (range 5% [5/93] for 10 mg once daily to 12% [22/186] for 60 mg once daily vs 5% [9/186]
269 uency ranged from 18% (17/93) for 10 mg once daily to 26% (24/91) for 60 mg twice daily, versus 16% (
271 or pH 5.5) was applied double-blinded twice daily to 6 AD patients and 6 healthy (HE) controls for 8
272 d (nutritionally enhanced mealworms supplied daily to meet 40%-50% of each supplemented brood's food
274 in-human study in postmenopausal women, once daily treatment with BAY 1214784 effectively lowered pla
275 -matched non-diabetic rats were subjected to daily uniaxial ulnar loading for 1, 4, 7, and 10 days, r
276 ptive therapy (valganciclovir, 900 mg, twice daily until 2 consecutive negative tests a week apart) f
277 ltispecies probiotics was administered twice daily upon start of antibiotic treatment, up to 1 week a
278 peration from 35 homes; and (2) characterize daily usage patterns over ~1-2 months per water heater t
282 that the biomarkers do not show significant daily variation, and that they are stable for up to 5 da
286 ion of more than 500 Billion USD and typical daily volume of 30 Billion USD, and manifests highly vol
288 mg once daily to 12% [22/186] for 60 mg once daily vs 5% [9/186] for placebo) and fatigue (1% [1/93]
291 reas under the curve for apixaban 5 mg twice daily were 5512 ng/(mL.h) and 3406 ng/(mL.h) for patient
292 ice daily and 75% receiving BOT 1.0 mg twice daily were in persistent remission compared with 4.4% of
293 m-coated tablet doses of 25 mg or 35 mg once daily, which were approved by the SRAs for the children'
294 either oral vancomycin (dosed at 125 mg once daily while receiving systemic antibiotics and continued
297 ng amiloride/hydrochlorothiazide (5 mg/50 mg daily) with dietary sodium restriction (60 mmol per day)
298 C [n = 747]) compared with DRV+r (800/100 mg daily) with FTC/TDF or ABC/3TC (n = 383) or EFV/FTC/TDF
299 vir disoproxil fumarate [TDF] or DOR [100 mg daily] with emtricitabine [FTC]/TDF or abacavir [ABC]/3T