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1 t confer strain-specific differences in bile deconjugation.
2  that contribute to CSN activation and Nedd8 deconjugation.
3 limination reactions, preventing nonspecific deconjugation.
4 ptide bond and study its Usp1/UAF1-dependent deconjugation.
5  dynamics of SUMO chains in vivo by constant deconjugation.
6 ving maturation, activation, conjugation and deconjugation.
7 ure form, and negatively, by catalyzing SUMO deconjugation.
8 minants of SUMO recognition, processing, and deconjugation.
9 cies that altered the bile acid pool through deconjugation.
10 talysed, stereo-controlled, strain-relieving deconjugation.
11 idase activity and end-products of bilirubin deconjugation.
12 t (Q116P) that is resistant to ATG4-mediated deconjugation.
13 resulted primarily from a deficit of SUMO2/3-deconjugation activity.
14 ghlight the importance of CSN-mediated NEDD8 deconjugation and adaptive exchange of CRL substrate rec
15 coli chassis reveals distinct differences in deconjugation and amidation activities, underscoring fun
16  physiological dose did not affect bile acid deconjugation and had little effect on other intestinal
17 gases through RUB (for Related to Ubiquitin) deconjugation and highlight the unequal role that CSN(CS
18  we developed a novel protease-assisted drug deconjugation and linker-like labeling (PADDLL) method t
19 erum samples were also analyzed by enzymatic deconjugation and liquid-liquid extraction (LLE) for the
20 ingent quality control while avoiding enzyme deconjugation and precolumn chemical derivatization.
21                                        Nedd8 deconjugation and re-engagement of the active site zinc
22 m Athens, Greece, were analyzed by enzymatic deconjugation and SPE.
23              The dynamics of conjugation and deconjugation and the role of SUMO during the cell cycle
24 in vivo, we highlight the importance of SUMO deconjugation, and we demonstrate the highly dynamic nat
25 uitin-related modifier (SUMO) processing and deconjugation are mediated by sentrin-specific proteases
26 acilitating isopeptidase SENP6-mediated SUMO deconjugation at telomeres.
27 nt tethered antibody formats, proteolysis or deconjugation at the fusion or conjugation site present
28             The method is based on enzymatic deconjugation, automated liquid-liquid extraction, and g
29 by a delicate balance between BA conjugation/deconjugation based on the bsh genes present.
30  that limits Smt3-protein ligation when Smt3 deconjugation by both Ulp1 and Ulp2 is compromised, allo
31 e modification is determined at the level of deconjugation by isopeptidases.
32                                        Early deconjugation by memory CD4 T cells is dependent on CD4-
33 lar basis for ubiquitin (Ub) recognition and deconjugation by MERS-CoV PL(pro), we determined its cry
34 more, we present the mechanism of SUMO chain deconjugation by SENPs, which occurs via a stochastic me
35                                     Although deconjugation can potentially occur in vivo to produce a
36 imide hydrolysis reaction over retro-Michael deconjugation can result in superb conjugation stability
37          These data identify SUMO4 as a SUMO deconjugation component and show that SUMO4:SENP1 are cr
38                                The enzymatic deconjugation efficiency, verified by deconjugation of u
39 as a conjugated internal standard to monitor deconjugation efficiency.
40     Deregulation of ubiquitin conjugation or deconjugation has been implicated in the pathogenesis of
41 th N-aryl maleimides exhibited less than 20% deconjugation in both thiol-containing buffer and serum
42  and that thiolate adducts undergo oxidative deconjugation in the presence of H(2)O(2), the pervasive
43  exogenous expression of either wild-type or deconjugation-inactive Usp18, and superimposition of an
44                                              Deconjugation is achieved by the SUMO protease ULP-4 and
45 rum of SUMO conjugates, indicating that SUMO deconjugation is substrate-specific and plays a critical
46 biotransformation (e.g., payload metabolism, deconjugation) leading to reduced or complete loss of ac
47 teractions between ubiquitin conjugation and deconjugation machineries and we examine the regulatory
48 hese results suggest that regulation of SUMO deconjugation may be a major facet of B23/nucleophosmin
49 s product release, with SUMO conjugation and deconjugation needed for each catalytic cycle, but this
50 in the analytical procedure indicted that no deconjugation occurred during the SPE procedure.
51                                              Deconjugation of ABA-GE by the endoplasmic reticulum and
52 7 degrees C; pH 6) was optimal condition for deconjugation of anthocyanidins and anthocyanins in urin
53  which the microbiota modify bile is through deconjugation of bile salts through bile salt hydrolase
54 ulfatases/glucuronidases results in complete deconjugation of conjugated CEHC.
55 utility of the method is demonstrated in the deconjugation of diverse electron-rich/electron-poor alk
56 econjugase enzyme (Arabidopsis thaliana) for deconjugation of folates (PE-LC-MS/MS), or animal-origin
57 soflavonoid absorption from the gut requires deconjugation of glucosides to aglycones.
58 perfamily and are best known to catalyze the deconjugation of glycine or taurine from bile salts to r
59  several factors involved in conjugation and deconjugation of Met1-linked polyubiquitin have been imp
60 led kinetic characterization of CSN-mediated deconjugation of Nedd8 from SCF.
61 he cleavage of NEDD8 from CRLs, and blocking deconjugation of NEDD8 traps the CRLs in a hyperactive s
62 ations in bile because of partial intestinal deconjugation of orally administered GCA.
63  that contribute to protease function during deconjugation of poly-SUMO chains.
64 ases (Ulp/SENPs) mediate both processing and deconjugation of small ubiquitin-like modifier proteins
65  full-length SUMO to its mature form and (2) deconjugation of SUMO from targeted proteins.
66 c process that requires both conjugation and deconjugation of SUMO moieties.
67 s, respectively, mediate the conjugation and deconjugation of SUMO molecules to/from target proteins.
68 roteases are required for the maturation and deconjugation of SUMO proteins, thereby either promoting
69              A family of proteases catalyzes deconjugation of SUMO-1-containing species.
70        It remained unknown, however, whether deconjugation of SUMO-1/Smt3 from proteins is also essen
71   Inhibition of viral DNA replication blocks deconjugation of SUMO-2 from Mre11 and Nbs1, indicating
72 ily of SUMO-specific proteases catalyzes the deconjugation of SUMO-modified proteins.
73    In the presence of inulin, more bacterial deconjugation of taurine from primary bile acids was obs
74                The inhibitor selectivity for deconjugation of the 26 and 17 kDa conjugates was simila
75                                 Photoinduced deconjugation of the extended pai-system within these ch
76 urine samples were processed using enzymatic deconjugation of the glucuronides followed by solid-phas
77  of the Active ADC, while exhibiting minimal deconjugation of the pyrrolobenzodiazepine (PBD) warhead
78              COP9 signalosome (CSN) mediates deconjugation of the ubiquitin-like protein Nedd8 from t
79  both heavy-light chain dissociation and the deconjugation of the warhead will affect the activity of
80 from substrates in a manner analogous to the deconjugation of Ub from eukaryotic proteins.
81 d as selective inhibitors of conjugation and deconjugation of ubiquitin catalyzed by reticulocyte fra
82                                              Deconjugation of ubiquitin from cellular proteins is cat
83                                     Specific deconjugation of ubiquitinated substrates has been descr
84 ymatic deconjugation efficiency, verified by deconjugation of urine samples spiked with alpha-naphthy
85                                    Microbial deconjugation of xenobiotics and release of aromatic moi
86 ght enhance the effectiveness of curcumin by deconjugation, production of active metabolites, and pro
87 ction studies suggest that Velo acts in SUMO deconjugation rather than in maturation.
88  a significant change in abundance after the deconjugation reaction.
89 hat SENP6 and SENP7 prefer SUMO2 or SUMO3 in deconjugation reactions with rates comparable with those
90 al microbiota of pregnancy enhance bile acid deconjugation, reducing ileal bile acid uptake and lower
91 served, yet the dynamics of SUMO conjugation/deconjugation remain poorly understood.
92                         Here, we developed a deconjugation-resistant form of NEDD8 to stabilize the n
93 ng under reducing and denaturing conditions, deconjugation-resistant LC3B accumulated in multiple for
94 imide ring hydrolysis, cysteinylation at the deconjugation site(s), and partial linker-payload cleava
95          Together, the IRF8 SUMO conjugation/deconjugation switch is part of a larger transition in S
96  microbial modifications including bile acid deconjugation that augments Fxr activity.
97 ted the balance between SUMO conjugation and deconjugation to continuously and bidirectionally fine-t
98 BA synthesis and catabolism, conjugation and deconjugation to glucose, and ABA transport all are invo
99 l ubiquitin-like modifier (SUMO) conjugation/deconjugation to heat shock transcription factors regula
100 epared with N-alkyl maleimides showed 35-67% deconjugation under the same conditions.
101                               Its subsequent deconjugation, which is broadly achieved by the human en
102  demonstrate that inhibition of bacterial BA deconjugation with a small-molecule inhibitor prevents t
103                           Thus, an enzymatic deconjugation with beta-glucuronidase was optimized.
104                          Selective enzymatic deconjugation with glucuronidase and mixed glucuronidase
105 gase activity, and it is presumed that Nedd8 deconjugation would reverse these effects.

 
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