ライフサイエンスコーパス: deep brain stimulation

1 raphy (during concurrent subthalamic nucleus deep brain stimulation).

2 Parkinson disease with bilateral subthalamic deep brain stimulation.

3 omputer-assisted planning and programming of deep brain stimulation.

4 ehn and Yahr stage 2.6) prior to surgery for deep brain stimulation.

5 m control and motor function recovery during deep brain stimulation.

6 rary lead externalization during surgery for deep brain stimulation.

7 s for feedback control in trials of adaptive deep brain stimulation.

8 ic scientists to probe mechanisms underlying deep brain stimulation.

9 odes implanted in the subthalamic nuclei for deep brain stimulation.

10 put synchrony onto the cortex, is altered by deep brain stimulation.

11 fective, and it is less invasive compared to deep brain stimulation.

12 and that these symptoms are treatable using deep brain stimulation.

13 transcranial direct current stimulation, and deep brain stimulation.

14 may contribute to the therapeutic effects of deep brain stimulation.

15 nd lateral motor areas was not influenced by deep brain stimulation.

16 l open the door for novel therapies, such as deep brain stimulation.

17 ith levodopa-carbidopa enteral suspension or deep brain stimulation.

18 severe refractory adults, psychosurgery and deep brain stimulation.

19 guided high intensity focused ultrasound and deep brain stimulation.

20 tients developed mild parkinsonism following deep brain stimulation.

21 RI data in patients with subthalamic nucleus deep brain stimulation.

22 luding surgery, vagus nerve stimulation, and deep brain stimulation.

23 ering the clinical implications for adaptive deep-brain stimulation.

24 ons between the therapeutic effectiveness of deep brain stimulation (3 months postoperatively) and de

25 skinesias, and underwent subthalamic nucleus deep brain stimulation 8 years after grafting.

26 Adaptive deep brain stimulation (aDBS) is a closed-loop method, w

27 Adaptive deep brain stimulation (aDBS) uses feedback from brain s

28 Deep brain stimulation allows drastic reduction of dopam

29 tonia can be effectively treated by pallidal deep brain stimulation although the mechanism of this ef

30 ariety of neurological procedures, including deep brain stimulation and craniotomies that require tis

31 e paper has widespread applicability to both deep brain stimulation and magnetic resonance guided hig

32 properties need to be explored for targeted deep brain stimulation and novel brain-computer interfac

33 Approaches such as deep brain stimulation and treatment with levodopa-carbi

34 work could bring antisense oligonucleotides, deep brain stimulation, and gene therapy into the clinic

35 anatomical circuits modulated by subthalamic deep brain stimulation, and infer about the inner organi

36 terpreting orofacial movements evoked during deep brain stimulation, and neuroimaging tractography ef

37 romodulation interventions, both invasive as deep brain stimulation, and non-invasive such as repetit

38 and during a movement task; once with active deep brain stimulation, and once with deep brain stimula

39 support the adjunctive use of neuroleptics, deep-brain stimulation, and neurosurgical ablation for t

40 glia function that have been used to develop deep brain stimulation approaches for Parkinson's diseas

41 Although the targets of deep brain stimulation are grey matter structures, axona

42 erventions, such as intrathecal baclofen and deep brain stimulation, are promising options.

43 thways, which were additionally modulated by deep brain stimulation, as well as modulation of local (

44 e movement task functional MRI data revealed deep brain stimulation-associated signal increases in th

45 high beta frequency range, but the degree of deep brain stimulation-associated suppression in their c

46 Furthermore, deep brain stimulation at clinically ineffective frequen

47 f the basal ganglia and serves as target for deep brain stimulation, but information on the functiona

48 tes of consciousness and inform how targeted deep brain stimulation can alleviate disorders of consci

49 While typically highly effective, deep brain stimulation can sometimes yield suboptimal th

50 In the long-term deep brain stimulation cohort (deep brain stimulation in

51 elates with the degree of improvement during deep brain stimulation, compatible with the current view

52 her developed to reliably identify effective deep brain stimulation contacts and aid in the programmi

53 tivity for the volume of tissue activated of deep brain stimulation contacts was assessed using proba

54 Deep brain stimulation (DBS) allows for direct recording

55 Deep brain stimulation (DBS) and cortical responsive sti

56 r symptoms, including gene therapy, adaptive deep brain stimulation (DBS) and optogenetically inspire

57 Emphasis was placed on deep brain stimulation (DBS) and randomized clinical tri

58 gated functional properties of the PCC using deep brain stimulation (DBS) and stereotactic electroenc

59 Deep brain stimulation (DBS) can be an effective therapy

60 Subthalamic nucleus (STN) deep brain stimulation (DBS) can improve motor complicat

61 Deep brain stimulation (DBS) depends on precise delivery

62 d potential (LFP) oscillations recorded from deep brain stimulation (DBS) electrodes within the VS ar

63 e subthalamic nucleus (STN) in patients with deep brain stimulation (DBS) electrodes.

64 allidus externa (GPe) in children undergoing deep brain stimulation (DBS) for dystonia and investigat

65 To explore the feasibility of deep brain stimulation (DBS) for intractable SIB seen in

66 The experience with deep brain stimulation (DBS) for pain is largely based o

67 The benefit of deep brain stimulation (DBS) for Parkinson disease (PD)

68 The efficacy of deep brain stimulation (DBS) for Parkinson disease (PD)

69 Subthalamic deep brain stimulation (DBS) for Parkinson's disease (PD

70 mparative studies of the efficacy of 'awake' deep brain stimulation (DBS) for Parkinson's disease (PD

71 pose a novel, closed-loop approach to tuning deep brain stimulation (DBS) for Parkinson's disease (PD

72 Deep brain stimulation (DBS) for Parkinson's disease is

73 activation in the therapeutic mechanisms of deep brain stimulation (DBS) for Parkinson's disease.

74 Based on the success of deep brain stimulation (DBS) for treating movement disor

75 fety and efficacy of neuroablation (ABL) and deep brain stimulation (DBS) for treatment refractory ob

76 A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-refractory ob

77 Deep brain stimulation (DBS) has been proposed for sever

78 Deep brain stimulation (DBS) has been shown to be an eff

79 Deep brain stimulation (DBS) has been used to treat a va

80 multiple sclerosis tremor using lesioning or deep brain stimulation (DBS) has been variable.

81 Deep brain stimulation (DBS) has improved the prospects

82 amic nucleus (STN) of PD patients undergoing deep brain stimulation (DBS) has now been translated int

83 For more than 15 years, deep brain stimulation (DBS) has served as a last-resort

84 Deep brain stimulation (DBS) has shown promise for treat

85 treating obsessive-compulsive disorder with deep brain stimulation (DBS) have been proposed.

86 Patients with deep brain stimulation (DBS) implants may be subject to

87 N), which serves as a therapeutic target for deep brain stimulation (DBS) in movement disorders, such

88 apeutic effects of subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson's disease (PD)

89 eus (PPTg) has been proposed as a target for deep brain stimulation (DBS) in parkinsonian patients, p

90 pplication in 1999, the potential benefit of deep brain stimulation (DBS) in reducing symptoms of oth

91 double-blind trial comparing active to sham deep brain stimulation (DBS) in the anterior limb of the

92 ort- and long-term antidepressant effects of deep brain stimulation (DBS) in treatment-resistant depr

93 assess whether dopaminergic medications and deep brain stimulation (DBS) influence Pavlovian bias.

94 Deep brain stimulation (DBS) is a circuit-oriented treat

95 Deep brain stimulation (DBS) is a clinical therapy used

96 Deep brain stimulation (DBS) is a neurosurgical procedur

97 Deep brain stimulation (DBS) is a promising tool for dev

98 Deep brain stimulation (DBS) is a promising treatment fo

99 Deep brain stimulation (DBS) is a surgical procedure use

100 Deep brain stimulation (DBS) is a treatment option for r

101 The clinical use of deep brain stimulation (DBS) is among the most important

102 Deep brain stimulation (DBS) is an effective interventio

103 Deep brain stimulation (DBS) is an effective treatment f

104 Deep brain stimulation (DBS) is an effective treatment o

105 Deep brain stimulation (DBS) is an emerging treatment fo

106 Deep brain stimulation (DBS) is known to be an effective

107 arge-balanced pulses used by the standard HF deep brain stimulation (DBS) is modulated by the smooth

108 therapeutic approach.SIGNIFICANCE STATEMENT Deep brain stimulation (DBS) is remarkably effective in

109 Deep brain stimulation (DBS) is used to treat a wide arr

110 Deep brain stimulation (DBS) is used to treat multiple n

111 dying the rewarding and punishing effects of deep brain stimulation (DBS) of subcortical emotional ne

112 Direct or indirect deep brain stimulation (DBS) of the entorhinal-hippocamp

113 Deep brain stimulation (DBS) of the subcallosal cingulat

114 Deep brain stimulation (DBS) of the subthalamic nucleus

115 Deep brain stimulation (DBS) of the subthalamic nucleus

116 morbid for a spectrum of sleep disorders and deep brain stimulation (DBS) of the subthalamic nucleus

117 Deep brain stimulation (DBS) of the subthalamic nucleus

118 Deep brain stimulation (DBS) of the subthalamic nucleus

119 Deep brain stimulation (DBS) of the subthalamic nucleus

120 Deep brain stimulation (DBS) of the subthalamic nucleus

121 The location of the optimal target for deep brain stimulation (DBS) of the subthalamic nucleus

122 Deep brain stimulation (DBS) of the subthalamic nucleus

123 with advanced Parkinson's can be treated by deep brain stimulation (DBS) of the subthalamic nucleus

124 Deep brain stimulation (DBS) of the subthalamic nucleus

125 n humans and rodents has explored the use of deep brain stimulation (DBS) of the ventral capsule/vent

126 ients failing ERP therapy are candidates for deep brain stimulation (DBS) of the ventral capsule/vent

127 Pi) in reward and punishment processing, and deep brain stimulation (DBS) of these structures has bee

128 Remarkably, deep brain stimulation (DBS) provides beneficial effects

129 Deep brain stimulation (DBS) reduces depressive symptoms

130 Closed-loop control is a promising deep brain stimulation (DBS) strategy that could be used

131 High-frequency deep brain stimulation (DBS) with a single electrical so

132 ement of focal lesions or the application of deep brain stimulation (DBS) within circuits that modula

133 Deep brain stimulation (DBS), a well established therape

134 son's disease who have undergone therapeutic deep brain stimulation (DBS), as in these individuals we

135 Parkinson's disease, on and off subthalamic deep brain stimulation (DBS), focussing on adaptive sens

136 leus (STN) or globus pallidus internus (GPi) deep brain stimulation (DBS), found that stimulation at

137 ith pallidotomy and then with high-frequency deep brain stimulation (DBS), has led to a renaissance i

138 the nature of motor activity in response to Deep Brain Stimulation (DBS), in the mouse.

139 ndWith growing numbers of patients receiving deep brain stimulation (DBS), radiologists are encounter

140 Chronic forniceal deep brain stimulation (DBS), recently shown to rescue h

141 Deep brain stimulation (DBS), targeting the subthalamic

142 When dyskinesia persists during therapeutic deep brain stimulation (DBS), the peak frequency of this

143 ed in vivo analysis of rodent's brains after deep brain stimulation (DBS).

144 on therapies to correct dysfunction, notably deep brain stimulation (DBS).

145 al and research tool for patients undergoing deep brain stimulation (DBS).

146 be accessed with surgical techniques such as deep brain stimulation (DBS).

147 n-human primate, swine, and rodent models of deep brain stimulation (DBS).

148 lation in some cases, was observed following deep brain stimulation (DBS).

149 tial tremor patients with bilateral thalamic deep brain stimulation (DBS).

150 internus (GPi), another effective target for deep brain stimulation (DBS).

151 t medical therapy (BMT, n=116) and bilateral deep brain stimulation (DBS, n=164) at either the subtha

152 rrespond to consistently successful sites of deep brain stimulation (DBS; essential tremor).

153 ipants diagnosed with ET undergoing thalamic deep brain stimulation (DBS; ET(DBS) ) to 19 healthy con

154 study, PD patients using Levodopa (n = 25), Deep Brain Stimulation (DBS; n = 6), de novo patients (n

155 vestigate the safety and targeting errors of deep-brain stimulation (DBS) electrodes placed under int

156 Furthermore, deep-brain stimulation (DBS) for psychiatric disorders t

157 that assessed the therapeutic impact of PPN deep-brain stimulation (DBS) in three patients with Park

158 plasticity induction by repeated pairing of deep-brain stimulation (DBS) of the BG with M1 stimulati

159 and sleep outcomes after subthalamic nucleus deep brain stimulation depends on the location of neuros

160 a control signal for closed-loop control of deep brain stimulation devices, for adjustment of dopami

161 Conventional deep brain stimulation did not change the distribution o

162 Furthermore, deep brain stimulation directed to the interposed cerebe

163 Modulating the altered activity with deep brain stimulation directed to the Purkinje cell out

164 med at elucidating key mechanisms supporting deep brain stimulation efficiency.

165 ncephalogram and local field potentials from deep brain stimulation electrodes in 9 Parkinson's disea

166 otential (LFP) recordings from patients with deep brain stimulation electrodes in the basal ganglia h

167 sensorimotor cortex were identified in which deep brain stimulation-evoked activation correlated with

168 e presence of paraesthesias, the most common deep brain stimulation-evoked adverse effect.

169 ic resonance imaging could be used to detect deep brain stimulation-evoked changes in functional and

170 n stimulation (3 months postoperatively) and deep brain stimulation-evoked changes in functional and

171 In addition, our findings indicate that deep brain stimulation-evoked functional activation maps

172 ion localizations, followed by evaluation of deep brain stimulation-evoked therapeutic and adverse ef

173 a-amplitude in primary motor cortex and that deep brain stimulation facilitates motor improvement by

174 ngitudinal data available after insertion of deep brain stimulation for medically refractory dystonia

175 streamlines, can predict clinical outcome of deep brain stimulation for obsessive-compulsive disorder

176 Deep brain stimulation for obsessive-compulsive disorder

177 been implicated in the clinical benefits of deep brain stimulation for Parkinson's disease.

178 deep brain stimulation, whereas conventional deep brain stimulation globally suppressed beta activity

179 neficial effects of globus pallidus internus deep brain stimulation (GPi DBS) on health-related quali

180 At 1 year post-deep brain stimulation, >50% of subjects showed BFMDRS-M

181 actions, and compared the modulatory effects deep brain stimulation had on different circuit componen

182 intrathecal infusion pumps, implantation of deep brain stimulation hardware, and general neurosurger

183 Deep brain stimulation hardware-related artifacts only a

184 While deep brain stimulation has been in the focus of academic

185 We propose that deep brain stimulation has both behaviour-independent ef

186 ng of functional MRI data has suggested that deep brain stimulation has modulatory effects on a numbe

187 High-frequency deep brain stimulation (HFS) is clinically recognized to

188 effects was conducted in 9 adults undergoing deep brain stimulation implantation surgery for chronic

189 electrode screening session, one month after deep brain stimulation implantation, the clinical benefi

190 e, efficient and selective than conventional deep brain stimulation, implying mechanistic differences

191 wireless ME stimulators provide therapeutic deep brain stimulation in a freely moving rodent model f

192 underwent ipsilateral ventral tegmental area deep brain stimulation in a specialist unit.

193 patients treated with ventral tegmental area deep brain stimulation in an uncontrolled, open-label pr

194 lity of reward and choice during therapeutic deep brain stimulation in four patients with treatment-r

195 Both animal studies and studies using deep brain stimulation in humans have demonstrated the i

196 bthalamic nucleus-the most common target for deep brain stimulation in Parkinson's disease-in cost-be

197 ropagation should inspire new rationales for deep brain stimulation in patients with intractable foca

198 ation in the motor cortex evoked ambulation, deep brain stimulation in the striatum caused rotation a

199 ore efficacious than conventional continuous deep brain stimulation in the treatment of Parkinson's d

200 us epilepticus, suggesting a pivotal role of deep brain stimulation in the treatment response.

201 e target of neurosurgical lesions as well as deep brain stimulation in these patients.

202 These results suggest that thalamic deep brain stimulation in tremor likely exerts its effec

203 ectional connectivity analysis revealed that deep brain stimulation increased the impact of the ventr

204 nd that the rest data were best explained by deep brain stimulation-induced increased (effective) con

205 the long-term deep brain stimulation cohort (deep brain stimulation inserted for >5 years, n = 8), im

206 Deep brain stimulation is a promising therapeutic approa

207 While high-frequency deep brain stimulation is a well established treatment f

208 Subthalamic nucleus deep brain stimulation is an effective treatment for adv

209 Deep brain stimulation is an established neurosurgical t

210 Deep brain stimulation is effective for patients with tr

211 Deep brain stimulation is now the treatment of choice fo

212 raoperative testing of subcallosal cingulate deep brain stimulation is unknown.

213 Neuromodulation of deep brain structures (deep brain stimulation) is the current surgical procedur

214 Subthalamic deep brain stimulation may alleviate bradykinesia in Par

215 Deep brain stimulation may be a treatment option in supe

216 Deep brain stimulation may be an effective therapy for s

217 Ventral tegmental area deep brain stimulation may be an effective treatment opt

218 e pilot studies have suggested that adaptive deep brain stimulation may potentially be more effective

219 Deep brain stimulation may represent a viable alternativ

220 ori local safety testing, patients receiving deep brain stimulation may safely undergo 1.5- and 3-T M

221 hese results offer a better understanding of deep brain stimulation mechanisms, promoting the develop

222 e therapeutic and adverse effects induced by deep brain stimulation.media-1vid110.1093/brain/aww145_v

223 son's disease, and helps inform how adaptive deep brain stimulation might best be delivered.

224 ght exist in which activation resulting from deep brain stimulation might correlate with the presence

225 study are illustrated by an index case where deep brain stimulation of estimated predominant non-moto

226 ecline in mitochondrial biomass, reversed by deep brain stimulation of subthalamic nucleus.

227 eted pharmacotherapy with Avpr1b agonists or deep brain stimulation of the CA2 are potential avenues

228 us that eventually resolved after commencing deep brain stimulation of the centromedian nucleus of th

229 es of dystonia may respond differentially to deep brain stimulation of the globus pallidus pars inter

230 Deep brain stimulation of the internal globus pallidus i

231 ssive compulsive disorder who have undergone deep brain stimulation of the limbic and associative sub

232 Deep brain stimulation of the nucleus accumbens (NAc-DBS

233 Deep brain stimulation of the subcallosal cingulate (SCC

234 n 13.3 +/- 6.3 years) who received bilateral deep brain stimulation of the subthalamic nucleus at the

235 ndings demonstrate that clinically effective deep brain stimulation of the subthalamic nucleus differ

236 Deep brain stimulation of the subthalamic nucleus is an

237 Deep brain stimulation of the subthalamic nucleus is an

238 Deep brain stimulation of the subthalamic nucleus is an

239 nson's disease patients undergoing bilateral deep brain stimulation of the subthalamic nucleus were i

240 rodes in Parkinson's disease patients, after deep brain stimulation of the subthalamic nucleus.

241 Deep brain stimulation of the vALIC resulted in a signif

242 Deep brain stimulation of the ventral anterior limb of t

243 Ten patients receiving deep brain stimulation of the ventralis intermedius thal

244 Previous case reports on deep brain stimulation of this region, now understood to

245 udy, we hypothesized that spatially targeted deep brain stimulation of ventromedial prefrontal cortex

246 Wireless deep brain stimulation of well-defined neuronal populati

247 This finding might explain why deep-brain stimulation of the STN can impair subjects' a

248 he modulatory effects of subthalamic nucleus deep brain stimulation on effective connectivity within

249 mechanisms mediating the clinical effects of deep brain stimulation on motor symptoms in Parkinson's

250 uence of the location of subthalamic nucleus deep brain stimulation on non-motor symptoms in patients

251 h the long-term therapeutic effectiveness of deep brain stimulation (P < 0.05), with the strongest co

252 , respectively, and that subthalamic nucleus deep brain stimulation predominantly suppresses the form

253 the return of pallidotomy, and subsequently deep brain stimulation procedures.

254 rents-a radical departure from commonly used deep brain stimulation protocols-is sufficient to modula

255 the relatively selective effect of adaptive deep brain stimulation provides a rationale for why this

256 Except for laryngeal dysphonia, deep brain stimulation provides a significant improvemen

257 Follow-up after deep brain stimulation ranged from 0.25 to 22 years.

258 Moreover, deep brain stimulation relatively selectively suppressed

259 te matter (WM) pathways, and the efficacy of deep-brain stimulation relies upon activation of WM.

260 Thalamic deep brain stimulation resulted in activation within est

261 lation is known to play an important role in deep brain stimulation's therapeutic mechanism.

262 lysis of responders to subcallosal cingulate deep brain stimulation (SCC DBS) for depression demonstr

263 Here, we demonstrate that deep brain stimulation selectively suppresses certain sp

264 Finally, the most effective deep brain stimulation sites for treating dystonia were

265 S.SIGNIFICANCE STATEMENT Subthalamic nucleus deep brain stimulation (STN DBS) is increasingly used in

266 Subthalamic nucleus deep brain stimulation (STN DBS) protects dopaminergic n

267 Subthalamic deep brain stimulation (STN-DBS) for Parkinson's disease

268 Subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease

269 patients both on and off subthalamic nucleus deep brain stimulation (STN-DBS), while they performed a

270 hypothesis that pairing subthalamic nucleus deep-brain stimulation (STN-DBS) with motor cortical tra

271 Although both adaptive and conventional deep brain stimulation suppressed mean beta activity amp

272 hat clinically effective subthalamic nucleus deep brain stimulation suppresses synchrony locally with

273 iatum of PD and dystonic patients undergoing deep brain stimulation surgeries.

274 eurons (SPNs) in patients with PD undergoing deep brain stimulation surgery, compared with patients w

275 affected by essential tremor and undergoing deep brain stimulation surgery, ventral intermediate nuc

276 acy across different clinical indications of deep brain stimulation surgery.

277 during temporary lead externalization after deep brain stimulation surgery.

278 ensorimotor cortex in 10 patients undergoing deep brain stimulation surgery.

279 led by medication or who were ineligible for deep-brain stimulation surgery to undergo focused ultras

280 active deep brain stimulation, and once with deep brain stimulation switched off.

281 ucleus' portions deemed to be appropriate as deep brain stimulation target to treat motor symptoms in

282 Deep brain stimulation targeted to the vALIC.

283 tion, our findings may be used to guide both deep brain stimulation targeting and programming and to

284 ory obsessive-compulsive disorder undergoing deep brain stimulation targeting the anterior limb of th

285 Commonly used deep brain stimulation targets such as the ventral inter

286 longside with the growth of neuroimaging and deep brain stimulation techniques.

287 frequency-based design in the development of deep brain stimulation therapy for PD.

288 Deep brain stimulation therapy is an effective symptomat

289 Sustained locking of deep brain stimulation to a particular phase of tremor a

290 ients with Parkinson's disease who underwent deep brain stimulation to compare spectral power and pow

291 input to the basal ganglia, is targeted with deep-brain stimulation to alleviate a range of neuropsyc

292 us is the preferred neurosurgical target for deep-brain stimulation to treat cardinal motor features

293 Effective adaptive deep brain stimulation truncated long beta bursts shifti

294 Parkinson's disease and subthalamic nucleus deep brain stimulation underwent functional MRI at rest

295 Adaptive deep brain stimulation uses feedback about the state of

296 ases of epilepsy, current procedures such as deep brain stimulation, vagus, and trigeminal nerve stim

297 Median age at deep brain stimulation was 11.5 years (range: 4.5-37.0 y

298 Improvement in mood and anxiety following deep brain stimulation was associated with reduced amygd

299 total of 105 dystonia patients with pallidal deep brain stimulation were enrolled and 87 datasets (43

300 ive effect on burst duration during adaptive deep brain stimulation, whereas conventional deep brain