ライフサイエンスコーパス: deep cerebellar nuclei

1 ivities at the injection sites (thalamus and deep cerebellar nuclei).

2 ch may disinhibit the output activity of the deep cerebellar nuclei.

3 e activity in both the cerebellar cortex and deep cerebellar nuclei.

4 ty of both Purkinje cells and neurons of the deep cerebellar nuclei.

5 g inhibition of cerebellar output neurons in deep cerebellar nuclei.

6 upts inhibition of the inferior olive by the deep cerebellar nuclei.

7 flexible selection of signals for output to deep cerebellar nuclei.

8 All injections labeled the deep cerebellar nuclei.

9 uced in Purkinje cells, but increased in the deep cerebellar nuclei.

10 otocols can drive synaptic plasticity in the deep cerebellar nuclei.

11 um without directly affecting neurons in the deep cerebellar nuclei.

12 stantia nigra pars reticulata, pallidum, and deep cerebellar nuclei.

13 enhanced hyperexcitability of neurons in the deep cerebellar nuclei.

14 sent in the olfactory bulb, red nucleus, and deep cerebellar nuclei.

15 es in the cerebellar cortex and in the lower deep cerebellar nuclei.

16 to extracerebellar structures by way of the deep cerebellar nuclei.

17 ulations vulnerable to weaver, including the deep cerebellar nuclei.

18 lum, it is expressed in Purkinje neurons and deep cerebellar nuclei.

19 ibular nuclei, inferior olivary complex, and deep cerebellar nuclei.

20 ss of lower motor neurons and neurons of the deep cerebellar nuclei.

21 raphically -distinct neurons in the anterior deep cerebellar nuclei (aDCN) that are activated by feed

22 nsmission at synapses from Purkinje cells to deep cerebellar nuclei and at vestibular synapses in mic

23 onto discrete populations of neurons in the deep cerebellar nuclei and brainstem vestibular nuclei.

24 --'50/40 pS'--openings) in some patches from deep cerebellar nuclei and dorsal horn neurones.

25 amatergic premotor projection neurons in the deep cerebellar nuclei and GABAergic neurons that feed b

26 nuclei, and the rhombic lip, which generates deep cerebellar nuclei and granule cells.

27 ons from layers four and five of the cortex, deep cerebellar nuclei and other localized brain regions

28 clei, hypothalamus, midbrain, pons, medulla, deep cerebellar nuclei and spinal cord, with tau-immunor

29 The specific role of deep cerebellar nuclei and the cerebellar cortex in eyeb

30 localized to specific areas within both the deep cerebellar nuclei and the cerebellar cortex.

31 components simulating cerebellar cortex and deep cerebellar nuclei, and it received input from a mid

32 trogliosis and vacuolation of neurons in the deep cerebellar nuclei, and the severe vacuolation of th

33 basal forebrain, the vestibular complex, the deep cerebellar nuclei, and the trapezoid body, a patter

34 learning in the cerebellar cortex versus the deep cerebellar nuclei; and (4) negative feedback from t

35 The projection neurons of the deep cerebellar nuclei are especially altered.

36 In contrast, targeted neurons in the deep cerebellar nuclei are known to unambiguously encode

37 or motor recovery, and lesions affecting the deep cerebellar nuclei are not fully compensated at any

38 ses formed by cerebellar Purkinje cells onto deep cerebellar nuclei as a model system, we confirm tha

39 s onto a Purkinje cell or onto a cell in the deep cerebellar nuclei become eligible for plasticity on

40 rtex (M1(L5)), while another arises from the deep cerebellar nuclei (Cb).

41 Transduction was evident in the deep cerebellar nuclei, cerebellar Purkinje cells, the b

42 Results suggest that lateral deep cerebellar nuclei contribute to visuospatial proces

43 isinhibition of the cerebellar cortex on the deep cerebellar nuclei could treat oculopalatal tremor.

44 istributed among many unlabeled cells in the deep cerebellar nuclei (DCbN).

45 , while low concentrations were found in the deep cerebellar nuclei (DCN) (30 ng/g [95% CI: 20, 41]).

46 We find that in mice the deep cerebellar nuclei (DCN) and vestibular nuclei (VN)

47 al lines of evidence have indicated that the deep cerebellar nuclei (DCN) are a site of memory storag

48 Neurons of deep cerebellar nuclei (DCN) are spontaneously active, a

49 The deep cerebellar nuclei (DCN) are the main output centers

50 The deep cerebellar nuclei (DCN) are the major output of the

51 In addition, we evaluated the use of the deep cerebellar nuclei (DCN) as a site for injection to

52 rat cerebellum, PNNs are found around large, deep cerebellar nuclei (DCN) neurons and Golgi neurons a

53 d the components of the neuropil in the four deep cerebellar nuclei (DCN) of the rat's brain.

54 Inhibitory projection neurons in the deep cerebellar nuclei (DCN) provide GABAergic input to

55 se, may be initiated by hyperexcitability of deep cerebellar nuclei (DCN) secondary to loss of inhibi

56 glutamatergic projection neurons within the deep cerebellar nuclei (DCN) that provide the primary ce

57 s within the mature fastigial pathway of the deep cerebellar nuclei (DCN), a region critical for bala

58 ween Purkinje neurons and the neurons of the deep cerebellar nuclei (DCN), a site that has been impli

59 prominently expressed around neurons of the deep cerebellar nuclei (DCN), but their role in adult ce

60 reactive to several brain regions, including deep cerebellar nuclei (DCN), globus pallidus, and thala

61 requency bursting activity in neurons of the deep cerebellar nuclei (DCN), which comprise the bulk of

62 als that received linear GBCAs showed higher deep cerebellar nuclei (DCN)-to-brainstem SI ratios comp

63 ination was examined with an emphasis on the deep cerebellar nuclei (DCN).

64 function is rebound firing in neurons of the deep cerebellar nuclei (DCN).

65 , posterior parietal cortex (area 5) and the deep cerebellar nuclei (DCN).

66 by including in our study the neurons of the deep cerebellar nuclei (DCN).

67 but that the classic cerebellar outputs, the deep cerebellar nuclei, do not directly project there.

68 clei (DRN) send projections to the fastigial deep cerebellar nuclei (fDCN) and that photostimulation

69 halamus, contralateral cerebellar cortex and deep cerebellar nuclei (FDR q < 0.05).

70 We conclude that the deep cerebellar nuclei have a bilateral movement represe

71 For example, in the deep cerebellar nuclei, Hebbian patterns of coincident s

72 ibuted between the cerebellar cortex and the deep cerebellar nuclei; (ii) the cerebellar cortex plays

73 importance of the cerebellar cortex and the deep cerebellar nuclei in eyeblink conditioning is uncle

74 of the parabrachial, lateral lemniscal, and deep cerebellar nuclei, in addition to cerebellar granul

75 k comprising the inferior olive, vermis, and deep cerebellar nuclei including the dentate nucleus dur

76 ons but strikingly similar to neurons in the deep cerebellar nuclei, indicating a common role for int

77 making microelectrode penetrations into the deep cerebellar nuclei (mainly nucleus interpositus) of

78 f vestibular signals from the vestibular and deep cerebellar nuclei may be important components of fu

79 nput that can be achieved in this way in the deep cerebellar nuclei may be particularly important to

80 uit, with relative increases in perfusion in deep cerebellar nuclei (medial, interposed, lateral), th

81 ed largely to the olfactory bulbs, midbrain, deep cerebellar nuclei, medulla, and spinal cord.

82 Here, I investigated the Purkinje cell to deep cerebellar nuclei neuron synapses (PC_DCNs), which

83 At synapses from Purkinje cells to deep cerebellar nuclei neurons (PC-->DCN), light- and el

84 e cells could explain the responses of these deep cerebellar nuclei neurons across all self-motion co

85 ABAA receptor-mediated monosynaptic IPSPs in deep cerebellar nuclei neurons by stimulation of Purkinj

86 Unlike vestibular and deep cerebellar nuclei neurons, where a mixture of respo

87 r Purkinje cells (which possess NR1 and 2D), deep cerebellar nuclei (NR1, 2A, 2B and 2D) and spinal c

88 Conclusion Increased signal intensity in the deep cerebellar nuclei of rats persists for at least 1 y

89 s made by Purkinje cells onto neurons in the deep cerebellar nuclei (PC to DCN synapses).

90 ollowing bilateral lesions targeting lateral deep cerebellar nuclei, rats were subjected to a bridge

91 (TEM-EDS) localization of gadolinium in the deep cerebellar nuclei showed ~ 100 nm electron-dense fo

92 nular cell layer, and loss of neurons in the deep cerebellar nuclei; spheroids and loss of myelinated

93 um and to pinpoint the exact location in the deep cerebellar nuclei that is necessary.

94 inclusions at atypical sites (e.g. thalamus, deep cerebellar nuclei) that are not typical for Lewy bo

95 TXN1 messenger RNA levels were >/=30% in the deep cerebellar nuclei, the cerebellar cortex, inferior

96 however, decreases Purkinje-cell synapses on deep cerebellar nuclei, the major output pathway of cere

97 -sensitive neurons in the most medial of the deep cerebellar nuclei, the rostral fastigial nucleus, w

98 In the deep cerebellar nuclei, the temporal increases in PBR pa

99 indbrain, including, but not limited to, the deep cerebellar nuclei, the trapezoid body, the red nucl

100 ing us to use optogenetic stimulation of the deep cerebellar nuclei to induce frequency-specific trem

101 coding of information also allows neurons of deep cerebellar nuclei to use a simple averaging mechani

102 glutamatergic neurons, namely neurons of the deep cerebellar nuclei, unipolar brush cells, and the la

103 luorescent protein (rAAV1.miS1eGFP) into the deep cerebellar nuclei using magnetic resonance imaging

104 iple brainstem motor nuclei, inferior olive, deep cerebellar nuclei, vestibular nuclear complex, nucl

105 cleus, oculomotor nucleus, substantia nigra, deep cerebellar nuclei, vestibular nucleus, and the thal

106 es prior to E12.5, with the exception of the deep cerebellar nuclei, we find that Math1 cells migrate

107 After AAV.miS1 delivery to deep cerebellar nuclei, we unexpectedly observed cerebel

108 binding and AT2 receptor mRNA levels in the deep cerebellar nuclei were also not affected by 3-acety

109 nt in cerebellar white matter and within the deep cerebellar nuclei, where neuron loss also occurred.

110 etected in the putamen, globus pallidus, and deep cerebellar nuclei, where the most dense areas of 8B

111 ction of Purkinje-cell axon terminals in the deep cerebellar nuclei, whereas the dendritic trees grew

112 Purkinje cells target the deep cerebellar nuclei, which are the output of the cere

113 effectively promote firing in neurons in the deep cerebellar nuclei with remarkable speed and precisi