ライフサイエンスコーパス: defy

1 l recent experiments, these expectations are defied.

2 ed to be a quirk of microscopic objects that defied a common-sense explanation.

3 gists, but this amazing cell type has so far defied a generalized classification system.

4 eristics of these energy transfer mechanisms defied a simple correlation between the time that the ex

5 nt of white adipose tissue (WAT) have so far defied a unifying hypothesis in terms of the kinship the

6 behavior between individual events seemingly defies a description with a simple unifying model.

7 high rate of adaptive evolution for 180 days defies a model of adaptation to a constant environment.

8 a observed since Kepler's supernova in 1604, defies a number of theoretical expectations.

9 This uncharacteristic epistasis interaction defies a paradigm in biochemical genetics arguing that m

10 teraction between AIRs and their cognate Ags defies a simple key-in-lock paradigm and is instead a co

11 cytochrome c with molecular adaptations that defy a conserved role in eukaryotic evolution.

12 s display anomalous transport phenomena that defy a Fermi liquid description.

13 tocrit are observed in various vessels, also defying a major principle of particulate suspension flow

14 However, some proteins defy accurate prediction due to factors such as inadequa

15 Spider silk has hitherto defied all attempts at reproduction, despite advances in

16 The disease has thus far defied all curative strategies.

17 ular, malignant glioblastoma multiforme have defied all current therapeutic modalities.

18 ce of TxCAD, a goal that has until this time defied all the advances in immunosuppression during the

19 Hofmeister effects continue to defy all-encompassing theories, and their origin is stil

20 ing from 3 years of meningoencephalitis that defied an etiologic diagnosis despite extensive conventi

21 asis of this important process has until now defied analysis.

22 e treatment, CN distribution among cells has defied analysis.

23 A significant fraction of proteins defies annotation through conventional sequence similari

24 A fundamental property of tumor cells is to defy anoikis, cell death caused by a lack of cell-matrix

25 Yet, defying anticipated FKN functions, absence of CX(3)CR1 i

26 s, but their number and complexity currently defy any molecular understanding of the physiology of sy

27 recovered specimen of algae and Insecta that defy any obvious other explanation at a depth of -3.4 km

28 d geographic breadth of this rapid radiation defy any single diversification paradigm, but implicate

29 in a mix of global and local processing but defies assigning it a single circuit function.

30 nknown sex-determining system especially has defied attempts at conventional analysis.

31 cades of research(1), chip floorplanning has defied automation, requiring months of intense effort by

32 eight unresolved paradoxes-ranging from size-defying barrier penetration to absent toxicity threshold

33 wildering to physicians and is considered as defying basic biology.

34 Historically, HBx has defied biochemical and structural characterization, dete

35 ual redox tailoring reactions that appear to defy biosynthetic logic.

36 han superconductivity presented in this work defies both empirical precedent and theoretical explanat

37 hese proposed rectification limits cannot be defied by any bi-segment thermal rectifiers.

38 as an elegant, monogenic model of neoplasia, defying categorization as either benign or malignant.

39 es of seroconversion and PCR positivity have defied causative linkage to severe acute respiratory syn

40 The section defies characterization with the biological species conc

41 es, like the Haldane phase in spin-1 chains, defy characterization through local order parameters.

42 e features, cause metastatic recurrences and defy chemotherapy, which leads to patients' demise.

43 ents on the energetics of an adjacent H-bond defies classical Hammett analysis.

44 As a fuzzy organelle, it defies classical organellar proteomics and cannot be des

45 Such robust surfaces, which defy classical expectations and can spontaneously recove

46 GrpE, or the binding of a peptide substrate, defying classical explanations for the chaperoning mecha

47 Although Nosmips currently defies classification, this strange and unexpected fossi

48 omus hoazin), an odd and enigmatic bird that defies classification.

49 Some "atypical" cases defy classification and show pancreatic beta-cell nuclea

50 ew types of thiotemplate assembly lines that defy classification are being discovered at an accelerat

51 eir small abundance and polymineralic nature defied commercial exploitation.

52 The assembly of the active site defies common chemical convention by contradicting the I

53 tion from rod-like to platelet crystals that defies common Ostwald ripening processes.

54 the low temperature 'hidden order' state has defied comprehensive understanding for over 30 years.

55 ces the largest flowers in the world and has defied confident phylogenetic placement since its discov

56 hylogenetic affinities of Tullimonstrum have defied confident systematic placement because none of it

57 h dynamics, we can ask how "outlier" species defy constraints.

58 Melanopsin ganglion cells have defied convention since their discovery almost 20 years

59 to the presence of multiscale features, and defies conventional methods.

60 This result defies conventional paradigms that prioritize increased

61 amido donors exert a weak ligand field, this defies conventional photosensitizer design principles.

62 This result defies conventional wisdom and suggests that distant pol

63 o also give the highest selectivities, which defies conventional wisdom.

64 and mudflats exhibit scaling properties that defy conventional power-law descriptions, presenting a l

65 ts of such large volume and complexity as to defy conventional scientific methodology.

66 Chaotic ecological dynamic systems defy conventional statistical analysis.

67 that tautomeric polymorph energy differences defy conventional wisdom by exceeding the normal 10 kJ/m

68 tatistical mechanics to design polymers that defy conventional wisdom by self-assembling into "megasu

69 al bonding and produce exotic compounds that defy conventional wisdom.

70 ore favorable, but paradoxes can emerge that defy conventional wisdom.

71 esponding increase in heat capacity of ~48%, defying conventional effective medium scaling of thermal

72 In defying conventional views that dismissed itch as trivia

73 evidence for molecular mass growth processes defying conventional wisdom that radical-radical reactio

74 n microbiology: despite its ubiquity, it has defied cultivation efforts.

75 s, presents ecotypic differentiation and has defied culturing efforts so far.

76 A description of such structures defies current traditional mechanical frameworks.

77 actions of chemicals dispersed in water that defy current chemical wisdom; reactions in electrified w

78 nsition states to enzymes, so strongly as to defy current understanding.

79 phic, ethnic and cultural diversity that can defy current universal models of healthy aging.

80 n generate remarkably complex responses that defy deep understanding of their contribution to behavio

81 Bacteriophages are enigmatic entities that defy definition.

82 ng of liquid metals at high temperatures has defied description and generalization.

83 cell signaling; however, these microdomains defy detection using conventional imaging.

84 mbracing deep subwavelength confinement that defies diffraction limits.

85 ne and often branching cell projections that defied direct visual resolution because of their size an

86 call this caspase-3 cleavage motif the Death Defying Domain (DDD).

87 problems for the selection process that have defied easy resolution.

88 e T-box family of transcription factor genes defy easy categorization.

89 These results defy easy classification: they show genomic patterns con

90 tes, and viruses is extremely rare and often defies ecological and functional explanations.

91 The heterogeneity of schizophrenia has defied efforts to derive reproducible and definitive ana

92 The structure of this region has defied elucidation due to its size, regional complexity,

93 alian cells in an aligned fibril network has defied elucidation.

94 nd its relation to thyroid gland dysfunction defies elucidation, and thus only palliative therapy exi

95 Presumably, the Reed-Sternberg cell defies endogenous apoptosis, persists, accumulates, and

96 Pseudomonas aeruginosa defies eradication by antibiotics and is responsible for

97 special eigenstates that counterintuitively defy ergodicity in quantum systems whose classical count

98 mu(3)-eta(1):eta(2):eta(2) binding mode that defies established paradigms for N(2) binding.

99 ordinary: an outlier among mammalian brains, defying evolutionary rules that apply to other species,

100 How it persists in the population and defies existing herd immunity is unknown.

101 ndrial inheritance also have been found that defy existing laws.

102 O has a completely novel suite of functions, defying existing "function-based" organelle classificati

103 onality effect on the transition temperature defies expectations from the Mermin-Wagner theorem, in c

104 physical phenomena or new compositions that defy expectations.

105 anges can have large, ramifying effects that defy expectations.

106 and Neptune have nondipolar magnetic fields, defying expectations that a thick interior layer of plan

107 in human-dominated landscapes, consistently defy expected biodiversity patterns based on island biog

108 lications, that have been predicted but have defied experimental verification.

109 y at the bed (< 10 mm) scale that has so far defied explanation by a single formative process.

110 A phenomenon that has defied explanation for two decades is the time scale for

111 y by biochemical analyses but whose role has defied explanation in terms of previous structural analy

112 here that vary over monthly time scales have defied explanation to date.

113 contemporary methane trends (1982-2017) have defied explanation with numerous, often conflicting, hyp

114 as an epigenetic phenomenon, 'mantling' has defied explanation, but here we identify the MANTLED loc

115 ture of the anti-Gal-binding RBC epitope has defied explanation, given that humans repress expression

116 multi-megabase arrays of DNA satellites, has defied explanation.

117 nclusions, CAIs) in meteorites have hitherto defied explanation.

118 istance is a complex metabolic disorder that defies explanation by a single etiological pathway.

119 in obese youth is a complex phenomenon that defies explanation by a single pathway.

120 h decreasing particle sizes in a manner that defies explanation by conventional quantum confinement.

121 r light, the SPP drag by electrical currents defies explanation by simple kinematics and is linked to

122 ic logic for their production is unknown and defies explanation via classical biochemical paradigms.

123 anged within circumscribed microdomains that defy explanation by conventional biosynthetic mechanisms

124 Water anomalies still defy explanation.

125 A basic phenomenon, defying explanation by traditional decision theories, is

126 ble spongiform encephalopathies (TSEs), have defied full characterization for decades.

127 r tyrosine kinase coactivation networks that defy full inhibition with single targeted drugs.

128 ashion to stereotypically spaced motifs that defy heterochromatin.

129 ding/unfolding is a complicated process that defies high-resolution characterization by experimental

130 ively characterized, FcR for IgM (FcmuR) has defied identification.

131 gest that the relevance of CCS is completely defied if the annual emission growth rate is in excess o

132 Helminth parasites defy immune exclusion through sophisticated evasion mech

133 In particular, its braincase and ear region defied interpretation, such that conventional anatomical

134 thogens such as human norovirus (HuNoV) have defied interrogation because they were previously uncult

135 However, inferred binding sites often defy intuition and the resulting LO decisions are often

136 Our approach defies intuitive interpretations in a picture of photons

137 of the first high-energy compound on earth, defies its extreme compositional and structural simplici

138 near arrangement of inorganic phosphates and defies its structural simplicity with an astounding numb

139 including TN cells) express endogenous GLS2, defying its role as a bona fide tumor suppressor.

140 Migrating sanderlings defy long distances but may end up in winter areas with

141 of magnitude lower than either constituent, defying long-standing composite bounds.

142 llenging to understand, especially when they defy manipulative experiments for practical or ethical r

143 olecular recognition, a task that has so far defied many conventional imaging approaches.

144 This complex earthquake defies many conventional assumptions about the degree to

145 y of dinoflagellates remains enigmatic: they defy many functional and genetic traits attributed to ty

146 For example, in epilepsy, which has largely defied mapping analysis, the underlying disease patholog

147 and can appear irrational in ways that have defied mechanistic explanations.

148 or patterns of virulence that have, to date, defied medical explanation.

149 a growing clinical problem that increasingly defies medical intervention.

150 These restrictions defy medical guidelines, lack scientific justification,

151 s that bias their transmission into gametes, defying Mendelian inheritance.

152 However, for decades, this disorder has defied molecular characterization.

153 le efforts, these critical host factors have defied molecular identification.

154 Flexible filamentous viruses have defied more than two decades of effort in fiber diffract

155 sitions and chemical reactions to occur that defy much of our understanding gained under ambient cond

156 dual measurements taken hours or days apart, defying naive statistical expectations.

157 d the need for tissue-to-electrode proximity defy non-invasive interfaces at scales of more than a th

158 outlandish features of the human genome that defy notions of ID by a caring cognitive agent.

159 Here, we report a symmetry-defying oriented attachment FeS(2) nanocrystal growth by

160 This protracted recovery defies our current understanding of climate regulation v

161 erns of divergence may, however, continue to defy our attempts to completely reconstruct them with co

162 dings have been largely ignored because they defy our common chemical understanding and evaded direct

163 Importantly, both explanations defy our current understanding of Mars' upper atmosphere

164 n distinct heritable phenotypes--continue to defy our understanding.

165 ent discoveries from time-domain surveys are defying our expectations for how matter accretes onto su

166 the protein greatly affected the phenotype, defying pathogenicity prediction algorithms.

167 cessive food consumption occurs in ways that defy personal insight or are below individual awareness.

168 d with resistance to apoptosis; 4) The death-defying phenotype of KCs does not require early differen

169 izes AlmG at the molecular level, showing it defies phylogenetic expectations to add amino acids to l

170 ent receptors and catalysts whose structures defy prediction.

171 ations of a fungal transcription factor that defies predictions on the basis of sequence alone.

172 understanding experimental observations that defy predictions of classical theories.

173 o RNS is often slow, is highly variable, and defies prognostication based on clinical factors.

174 has slowed markedly over the last 20 years, defying projections despite a growing beneficiary popula

175 sis until autopsy or transplantation and has defied proper treatment trials for its rarity and deadly

176 assemblies underlie diverse tauopathies but defy rapid classification.

177 As such, the origin of animals defies retrospective explanations.

178 tum correlations violating Bell inequalities defy satisfactory causal explanations within the framewo

179 en mammalian brain and body mass continue to defy satisfactory explanation.

180 This gap in averages defies simple intuitive explanations, applies to globall

181 population density and reserve effectiveness defy simple explanation but may depend on human migratio

182 e muscle contraction and muscle stretch that defy simple explanation.

183 ely reproduce observed neural activity often defy simple interpretations.

184 s in promoting autoimmunity, the newest data defy simple paradigms.

185 corresponding solution state optical spectra defy simple structure-optical property correlations.

186 , and carbenes (R(2)C:)-two-coordinate octet-defying species with formally six valence electrons(3).

187 Cocaine addiction and overdose have long defied specific treatment.

188 mo), a 7-pass integral membrane protein, has defied standard biochemical characterization.

189 able to diverse cancer incidences previously defying standard treatments.

190 irus superantigens (vSAGs) are notorious for defying structural characterization, and a consensus has

191 to treat cocaine use disorders has thus far defied success, leaving this patient population without

192 istics forms and their phonetic realizations defy such heuristics.

193 pparent wandering of axons across the repair defies surgical control and mandates a biological approa

194 (4), which violates this relationship not by defying symmetry-imposed selection rules but by invoking

195 ly substituted aromatic building blocks that defy synthesis via existing methods.

196 as zone is not a phase boundary and has thus defied systematic description.

197 any sexual selection models, but has largely defied testing due to the challenges of quantifying the

198 uring operations in indefinite causal order, defying that events be causally ordered at all.

199 The eastern tropical Pacific has defied the global warming trend.

200 common cancers in Western countries but has defied the trend of reductions in age-adjusted mortality

201 antiferromagnetic SrIr(0.8)Sn(0.2)O(3) that defies the antisymmetric constraint on the anomalous Hal

202 n selectively adsorb oxygen in a manner that defies the classical picture: adsorption sites either do

203 g and manufacturing a novel waveplate, which defies the fundamental limit of bandwidth and incident a

204 a non-conventional transport mechanism that defies the fundamental tenets of the alternating-access

205 ormation for Ni, more so than with Pd, which defies the generally assumed trends that beta-hydride el

206 ts have demonstrated metallic behaviour that defies the Landau Fermi paradigm(1-5).

207 chanism, as the variation that HIV generates defies the limits of the T cell repertoire.

208 L is organized as an atypical hierarchy that defies the strict lineage marker boundaries and unidirec

209 In different ways, each species defies the tendency for tropical birds to have long-term

210 erences for cues associated with the parent) defies the traditional rules of learning in that it seem

211 These two characteristics defy the classical object-observer duality, making BMIs

212 are widespread and important in biology but defy the classical protein structure-function paradigm b

213 ite of N-methyl D-aspartate (NMDA) receptors defy the concept that a neurotransmitter must be synthes

214 To determine whether these genes defy the concerted evolution paradigm, we examined the p

215 stable G-quadruplex structures, all of them defy the description of sequences G3+NL1G3+NL2G3+NL3G3+,

216 micrometre scale, however, colloids in water defy the intuitively simple idea of forming crystals fro

217 e K(d)(Mn(II)) of 29 and 7 uM, respectively, defy the Irving-Williams series to selectively detect Mn

218 Second, findings that defy the orthodoxy of oncogenic "driver mutations" are n

219 es in ceramide metabolism and structure that defy the prevailing unifying hypothesis on ceramide func

220 h surprisingly shallow slopes that seemed to defy the quasi-exponential k(ch)(T) dependence.

221 understood, nor is it clear how individuals defy the risks associated with drugs or addiction vulner

222 However, some metal alloys are known to defy the rules of crystallography and form so-called qua

223 imensional topological semimetal CoSi, which defy the standard description in two fundamental aspects

224 e performance of elite athletes is likely to defy the types of easy explanations sought by scientific

225 Defying the common Diels-Alder reactivity, the thermal c

226 ficiency (the beta-factor) over large areas, defying the common wisdom that the beta-factor degrades

227 uctivity of ~0.55 W m(-1) K(-1) at 298 K and defying the conventional correlation between mass and la

228 in real space at quantized magnetic fields, defying the conventional optical selection rules.

229 ized by a bis(alpha-iminopyridine) ligand L, defying the Coulombic repulsion.

230 f the protective immune response against it, defying the development of an effective vaccine.

231 rt effector functions for prolonged periods, defying the mechanisms that normally curb their capaciti

232 tinuously tunable, triaxial, tensile strain, defying the Poisson ratio of the embedded material and a

233 hic proteins switch between different folds, defying the protein folding paradigm.

234 Defying the requirements of translational periodicity in

235 Au is very similar at the SOR and NR levels, defying the typically robust correlation between MP and

236 ribonucleic acid (RNA) on the cell surface, defying the view that RNA only functions intracellularly

237 an astounding range of complex behavior that defies their categorization as solid, liquid, or gas.

238 some main-sequence stars, these white dwarfs defy their conventional portrayal as dead stars.

239 es, and fail when applied to individuals who defy them.

240 ation in the past must have been very large, defying theoretical explanations.

241 a cause of death among premature babies, has defied therapeutics for decades.

242 b for designing exotic many-body states that defy thermalization.

243 of which contained the spike E484K mutation) defied these trends and persisted at moderately increasi

244 b chains in an insulating perovskite crystal defy these conventional expectations.

245 Defying these expectations, the adoptive transfer of IL-

246 However, many cases of chronic pain have defied this logic, leaving clinicians perplexed as to ho

247 s, which can exhibit critical behaviour that defies this description and is not well understood(1).

248 Proteusins are RiPP precursor peptides that defy this characterization as they possess unusually lon

249 However, some protein regions defy this constraint, with protein activity dictated mor

250 lifetimes, yet there are many examples that defy this convention by displaying remarkable stability.

251 Our findings defy this paradigm by demonstrating that cicadas-weighin

252 To defy this paradigm, we describe novel design principles

253 t least-studied venomous lineages, appear to defy this rule.

254 s the iron-based materials, which extend and defy this understanding in unexpected ways.

255 s the regime of "signal-dependent noise" and defies traditional decoding approaches.

256 umber and lack of movement of chromatophores defies traditional Turing-type pattern generating mechan

257 e 1990, whereas rising adult mortality rates defy traditional epidemiological transition models in wh

258 nt offsets in space and in time, which often defy traditional mechanistic explanations.

259 sms of the human central nervous system have defied treatment, in part because of the limited selecti

260 Photogranulation defies typically postulated requirements for granulation

261 The flow of water in carbon nanochannels has defied understanding thus far(1), with accumulating expe

262 intensive research, multiple sclerosis (MS) defies understanding and treatment remains suboptimal.

263 The regulatory system is so complex that it defies understanding by verbal arguments alone.

264 often exhibit diverse learning trajectories, defying understanding of its underlying dopaminergic mec

265 to date, the collective mass in graphene has defied unequivocal measurement.

266 ence and the diverse use of animals globally defies uniform bans.

267 g rates in underrepresented populations pose defies, with many pathogenic mutations still awaiting di