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4 bjects also exhibited a blunted and somewhat delayed type 1 T cell response to influenza vaccination,
5 erely impaired in IL-25(-/-) mice, including delayed type 2 cytokine responses, an attenuated functio
7 tact hypersensitivity (CHS) in the skin is a delayed type cellular immune response that can be mediat
8 suppression as measured by the inhibition of delayed type contact hypersensitivity to the chemical di
9 inflammation and hypersensitivity as well as delayed-type contact hypersensitivity were attenuated in
11 ranscriptase inhibitor often inducing severe delayed-type drug hypersensitivity, can trigger innate i
14 tion correlates with a strong induction of a delayed type hypersensitivity (DTH) response following e
16 IMP-1 and TIMP-2 had differential effects on delayed type hypersensitivity (DTH) responses to donor a
20 tivity, and cytokine production in vitro and delayed type hypersensitivity and inflammatory bowel dis
21 onor-specific regulation (DSR) by trans-vivo delayed type hypersensitivity assay at the time of enrol
22 rs before transplant and used the trans-vivo-delayed type hypersensitivity assay to measure immune re
24 transplants as responders in the trans vivo-delayed type hypersensitivity assay, we found that dendr
27 f systemically activated T cells home to the delayed type hypersensitivity reaction induced by the ov
28 tenuated in subjects who are able to mount a delayed type hypersensitivity reaction to M. tuberculosi
30 quisition of the capacity to mount cutaneous delayed type hypersensitivity reactions that disappeared
31 K14-mOVA Tg mice failed to mount T cell and delayed type hypersensitivity reactions to OVA, suggesti
32 global immunity as reflected by an enhanced delayed type hypersensitivity response and a 1.7-fold im
34 allogeneic tumor cells or the suppression of delayed type hypersensitivity responses against soluble
37 n a mucosal tolerization schedule suppressed delayed type hypersensitivity to E-selectin confirming t
38 proliferation of T(EM) cells and suppresses delayed type hypersensitivity when administered at 10 or
39 liferation of human TEM cells and suppresses delayed type hypersensitivity, a TEM cell-mediated react
40 me-linked immunosorbent assay, Western blot, delayed type hypersensitivity, and enzyme-linked immunos
42 autoreactive anti-MPO CD4(+) cells to induce delayed type hypersensitivity-like necrotizing glomerula
45 antibodies and histopathologic, RT-PCR, and delayed-type hypersensitivity (DTH) analyses were used t
46 ompanied by vigorous cardiac myosin-specific delayed-type hypersensitivity (DTH) and antibody product
47 these mice developed cardiac myosin-specific delayed-type hypersensitivity (DTH) and autoantibodies i
48 st skin-infiltrating lymphocytes in allergic delayed-type hypersensitivity (DTH) and bacterial chancr
49 acy of JAK-3 inhibitors was determined using delayed-type hypersensitivity (DTH) and collagen-induced
50 e absence of injury, aged mice had depressed delayed-type hypersensitivity (DTH) and splenocyte proli
54 s mediate the suppression of donor-specific, delayed-type hypersensitivity (DTH) in tolerant organ tr
55 both in vitro and in vivo in an Ag-specific delayed-type hypersensitivity (DTH) model in the cynomol
56 The effects of age, sex, and prevaccination delayed-type hypersensitivity (DTH) on the time course o
57 positive (responsive) or negative (anergic), delayed-type hypersensitivity (DTH) reaction to intrader
62 tory lymphokine essential for elicitation of delayed-type hypersensitivity (DTH) reactions in vivo.
63 the selectins play a role and predominate in delayed-type hypersensitivity (DTH) reactions of the ski
64 Systemic exposure to LTA or CPAF inhibited delayed-type hypersensitivity (DTH) reactions to the che
65 l inflammatory diseases including psoriasis, delayed-type hypersensitivity (DTH) reactions, and rheum
68 e and central memory subsets and inhibit the delayed-type hypersensitivity (DTH) response caused by s
69 o sand fly saliva in rodents induces a T(H)1 delayed-type hypersensitivity (DTH) response conferring
70 val, adverse events (AEs), and the effect of delayed-type hypersensitivity (DTH) response on clinical
72 /6 mice with indoles (I3C or DIM) attenuated delayed-type hypersensitivity (DTH) response to methylat
73 plex virus type 1 (HSV-1) develop a vigorous delayed-type hypersensitivity (DTH) response upon intrad
74 ized severe C. pneumoniae disease as being a delayed-type hypersensitivity (DTH) response with increa
75 antigen-specific proliferation in vitro, the delayed-type hypersensitivity (DTH) response, and serum
76 uppression in septic patients is an impaired delayed-type hypersensitivity (DTH) response, manifested
77 cterium bovis-specific antigens to stimulate delayed-type hypersensitivity (DTH) responses in cattle
78 n PPD were tested for the capacity to induce delayed-type hypersensitivity (DTH) responses in H37Rv-i
79 mmune cell infiltration at vaccine sites and delayed-type hypersensitivity (DTH) responses to autolog
82 disease had high IgG antibody titers and no delayed-type hypersensitivity (DTH) responses to Leishma
83 mmunity, we hypothesized that decreased skin delayed-type hypersensitivity (DTH) responses to recall
87 ns ESAT-6, CFP-10, MPB70, and MPB83 elicited delayed-type hypersensitivity (DTH) skin test responses
89 egimen suppressed the strong myosin-specific delayed-type hypersensitivity (DTH) that normally develo
91 polygyrus infection reduced the magnitude of delayed-type hypersensitivity (DTH) to PPD in the skin.
94 rfered with cell-mediated immunity as myosin delayed-type hypersensitivity (DTH) was reduced, while a
95 ssential mediators of autoimmune disease and delayed-type hypersensitivity (DTH), a convenient model
96 t survival, graft infiltration, allospecific delayed-type hypersensitivity (DTH), and cytokine expres
97 uble RAGE treatment is effective in reducing delayed-type hypersensitivity (DTH), even in RAGE(-/-) m
98 responsiveness by the ear-swelling test for delayed-type hypersensitivity (DTH), in vitro proliferat
105 e differed from wild-type in the severity of delayed-type hypersensitivity (edema, T-cell and neutrop
107 velopment of specific antibody (P = .025) or delayed-type hypersensitivity (P = .03) responses to EGF
108 atic acid phosphatase (PAP) and a trans-vivo delayed-type hypersensitivity (tvDTH) assay, we found th
109 ic VL, (ii) asymptomatic infection (positive delayed-type hypersensitivity [DTH+]), or (iii) no evide
110 tein 60 was the only antigen shown to induce delayed-type hypersensitivity among other antigens teste
111 eactive T cells by ELISPOT and by trans-vivo delayed-type hypersensitivity analysis in a surrogate mu
113 HHE) associated with salutary or detrimental delayed-type hypersensitivity and AIDS phenotypes, respe
114 or in vivo inhibition, causing enhanced skin delayed-type hypersensitivity and antigen (Ag)-induced a
115 s several type 1 immune responses, including delayed-type hypersensitivity and autoimmunity in which
116 T cell responses and reduced inflammation in delayed-type hypersensitivity and clinical disease in EA
117 lammation and autoimmunity, murine models of delayed-type hypersensitivity and collagen-induced arthr
118 A in the a.c. displayed reduced OVA-specific delayed-type hypersensitivity and CTL responses, compare
119 ific mAb inhibited T cell-mediated models of delayed-type hypersensitivity and experimental autoimmun
123 f AnxA1 also increased OVA-induced cutaneous delayed-type hypersensitivity and IFN-gamma and IL-17 re
124 lin epitope-specific Th1 effector functions (delayed-type hypersensitivity and IFN-gamma production)
125 ducing T lymphocyte-mediated inflammation in delayed-type hypersensitivity and in experimental autoim
127 reated mice, as indicated by reduced in vivo delayed-type hypersensitivity and reduced levels of sple
128 icking to draining lymph nodes, induction of delayed-type hypersensitivity and rejection of corneal t
129 age-related T cell dysfunction, Ag-specific delayed-type hypersensitivity and T cell proliferation w
130 n control IgG exhibited impaired Ag-specific delayed-type hypersensitivity and T cell proliferation,
131 that excessive activity of T cells mediates delayed-type hypersensitivity and that cellular cytolysi
138 from C57BL/6 CD4 KO mice were assessed using delayed-type hypersensitivity assays and Annexin V apopt
144 immunopathology was found to be operative in delayed-type hypersensitivity footpad-swelling reaction
145 these cells to present Ag for elicitation of delayed-type hypersensitivity in previously immunized mi
146 of Th2 enhancement, as indicated by reduced delayed-type hypersensitivity in the context of enhanced
148 press the keyhole limpet hemocyanin-specific delayed-type hypersensitivity inflammatory response.
149 sessment of Th1 function using the cutaneous delayed-type hypersensitivity model confirmed that p53(-
150 stopathological analysis of tissues from the delayed-type hypersensitivity model demonstrates that in
152 (+) T cell responses were also observed in a delayed-type hypersensitivity model in which mTORC2 was
154 able to reduce inflammation in a murine paw delayed-type hypersensitivity model, suppress the onset
156 a T cells do not cause direct suppression of delayed-type hypersensitivity nor do they act as tolerog
158 compound showed good efficacy in an in vivo delayed-type hypersensitivity pharmacology model in rats
159 nodes (LNs) of mice with cOVA-induced airway delayed-type hypersensitivity reaction (DTHR) but not in
160 king RON exhibit increased inflammation in a delayed-type hypersensitivity reaction and increased sus
166 d with E. chaffeensis, the animals developed delayed-type hypersensitivity reactions at cutaneous sit
167 naling of human T cells in vitro and reduces delayed-type hypersensitivity reactions in rats in vivo.
168 terolemia is frequent in these patients, and delayed-type hypersensitivity reactions in the arterial
170 ve indicated that UVB-mediated inhibition of delayed-type hypersensitivity reactions is mediated, in
173 Immunization stimulated the development of delayed-type hypersensitivity reactions to irradiated, d
174 Immunization stimulated the development of delayed-type hypersensitivity reactions to irradiated, d
175 2) in the control of cutaneous inflammation, delayed-type hypersensitivity reactions were elicited in
176 e responses against intracellular pathogens, delayed-type hypersensitivity reactions, and induction o
181 showed that IL-27 regulated the severity of delayed-type hypersensitivity response and EAE through i
182 icance of the role of IL-27 was addressed in delayed-type hypersensitivity response and experimental
183 ignificantly stronger CD4(+) T-cell-mediated delayed-type hypersensitivity response and resulted in s
184 ry effect of alpha(1)beta(1) blockade on the delayed-type hypersensitivity response could be bypassed
185 owever, IL-10-deficient mice had an enhanced delayed-type hypersensitivity response during the chroni
186 ed allografts did not elicit an alloreactive delayed-type hypersensitivity response in graft recipien
188 fluence of photoperiod and acute stress on a delayed-type hypersensitivity response in the skin.
191 IL-10 transgenic mice demonstrated a smaller delayed-type hypersensitivity response to allogeneic cel
192 lymph nodes and allografts, 2) a suppressed delayed-type hypersensitivity response to B6D2F1 Ags, an
193 rative responses and a significantly reduced delayed-type hypersensitivity response to challenge anti
194 trates demonstrated a much weaker peripheral delayed-type hypersensitivity response to donor alloanti
195 et KO cells, gastritis was associated with a delayed-type hypersensitivity response to H. pylori anti
196 Lastly, P763.74, but not PGH786, induced a delayed-type hypersensitivity response to HMW-MAA-bearin
197 spleen T cells in vitro and inhibition of a delayed-type hypersensitivity response to oxazolone in v
198 on-induced immunosuppression, resulting in a delayed-type hypersensitivity response to photo-induced
199 -MEM mice responded with an enhanced footpad delayed-type hypersensitivity response, and more IFN-gam
200 lin E and inhibition of the anticryptococcal delayed-type hypersensitivity response, indicating a shi
205 rdiac myosin (autoimmunity) but did decrease delayed-type hypersensitivity responses against both ant
206 , characterized by Ag-specific inhibition of delayed-type hypersensitivity responses and a reduction
207 n the periphery, which resulted in increased delayed-type hypersensitivity responses and autoimmune d
209 Our data demonstrate that decorin modulates delayed-type hypersensitivity responses by augmenting th
210 induced Ag-specific T cell proliferation and delayed-type hypersensitivity responses in FcgammaRIIB-e
211 orphisms and haplotype pairs that influenced delayed-type hypersensitivity responses in healthy perso
212 reduced IFN-gamma production, and inhibited delayed-type hypersensitivity responses in immune mice c
213 ls, which failed to undergo proliferative or delayed-type hypersensitivity responses in recipients.
215 zation, because Jak3-/- chimeric mice showed delayed-type hypersensitivity responses indistinguishabl
216 administration of MSCs significantly reduced delayed-type hypersensitivity responses to allogeneic an
218 ermined by the level of serum antibodies and delayed-type hypersensitivity responses to HMW-MAA-beari
219 yeloperoxidase CD4+ T cells, enhanced dermal delayed-type hypersensitivity responses to myeloperoxida
222 n 42 patients with leprosy were compared for delayed-type hypersensitivity responses to purified prot
223 ount but was associated with higher rates of delayed-type hypersensitivity responses to TT (25% of su
224 of murine CD8(+) dendritic cells to suppress delayed-type hypersensitivity responses to tumor-associa
226 41 vaccination decreased corneal opacity and delayed-type hypersensitivity responses while elevating
227 combinant murine IL-10 were able to suppress delayed-type hypersensitivity responses within injected
229 Cs including enhanced T-cell reconstitution, delayed-type hypersensitivity responses, and class-switc
230 nterferon gamma-producing T cells, increased delayed-type hypersensitivity responses, and higher seru
231 es: rash, high fever, viremia, depression of delayed-type hypersensitivity responses, lowered leukocy
232 not age, was associated with impairments in delayed-type hypersensitivity responses, lymphoprolifera
233 ed bystander suppression of tetanus-specific delayed-type hypersensitivity responses, which was rever
234 rvival demonstrated prominent donor-reactive delayed-type hypersensitivity responses, which were incr
240 tor and memory T cells inhibited Ag-specific delayed-type hypersensitivity responses; similar decreas
243 ral load, baseline CD4(+) T cell counts, and delayed-type hypersensitivity skin test responses, an in
247 s II expression on macrophages, and restored delayed-type hypersensitivity to a model hapten, consist
248 hermore, ATPgammaS enhanced the induction of delayed-type hypersensitivity to a model tumor vaccine i
249 in the hosts and inhibited the expression of delayed-type hypersensitivity to donor alloantigens.
251 of healthy subjects have tested positive for delayed-type hypersensitivity to soluble leishmania anti
252 ed immunologic memory and the elicitation of delayed-type hypersensitivity to the common opportunisti
254 vels of inflammation were seen in a model of delayed-type hypersensitivity using 2,4-dinitrofluoroben
258 nd gastric epithelial metaplasia), cellular (delayed-type hypersensitivity) and humoral immune respon
259 reactions triggered by immune (immediate and delayed-type hypersensitivity) and non-immune (intoleran
261 beta1AR(-/-) mice had improved cellular (delayed-type hypersensitivity) responses while beta2AR(-
262 nted a hallmark of sepsis (i.e., the loss of delayed-type hypersensitivity), which is an IFN-gamma- a
263 ction of antigen inhibits the development of delayed-type hypersensitivity, a phenomenon known as ant
264 mice exhibited T cell priming by peptide and delayed-type hypersensitivity, although these responses
265 , MAS, mean and cumulative arthritis scores, delayed-type hypersensitivity, and antibody responses to
266 , suppress primarily Th1 responses including delayed-type hypersensitivity, and transfer suppression
267 nies many type 1 immune responses, including delayed-type hypersensitivity, autoimmunity, and graft r
270 In a more generalized model of inflammation, delayed-type hypersensitivity, CP-481,715 significantly
271 respect to disease induction, enhancement of delayed-type hypersensitivity, enhancement of lymphocyte
272 clude mixed lymphocyte reactions, trans-vivo delayed-type hypersensitivity, enzyme-linked immunospot
273 es of T cell function--ranging from positive delayed-type hypersensitivity, in asymptomatic infected
274 ain aspects of immune function, particularly delayed-type hypersensitivity, may be improved in HD pat
276 lls and prevented these mice from developing delayed-type hypersensitivity, which is critically depen
277 nate immune activation to medication-induced delayed-type hypersensitivity, which may stimulate new c
290 of immunity by B. dendrobatidis, a modified delayed-type-hypersensitivity (DTH) protocol was develop
291 inished memory T-cell populations, decreased delayed-type-hypersensitivity responses and decreased in
293 rum specific IgE antibodies to alpha-gal and delayed type I allergic reactions to the carbohydrate al
294 In addition, IRF-3-deficient BMDCs exhibited delayed type I IFN synthesis compared to control cells.
295 that robust virus replication accompanied by delayed type I interferon (IFN-I) signaling orchestrates
296 hypersensitivity (CHS) is a T cell-mediated delayed-type immune response which has been considered t
297 mechanism-mediated finding consistent with a delayed-type immune-mediated type IV hypersensitivity in
298 also been implicated in type IV (also termed delayed-type or T cell-mediated) hypersensitivity reacti
299 vity to corticosteroids is a common finding, delayed-type reactions being much more frequently encoun