ライフサイエンスコーパス: delete

1 l region that is duplicated in Dup22q11.2 is deleted.

2 r oligodendroglioma, IDH-mutant and 1p19q co-deleted.

3 5c has been deleted.

4 ithelial cells whose Naked/NKD HisC has been deleted.

5 germ line when the primordial germ cells are deleted.

6 hydrolysis even when their Ubl domains were deleted.

7 gattii genome, either centromere 9 or 10 was deleted.

8 ly when two related enzymes are concurrently deleted.

9 ession when Nppb and flanking sequences were deleted.

10 Deleting 1 point of pLI decreases IQ by 2.6 points in au

11 Similar benefits accrued from genetically deleting 1 SCD allele, providing target validation.

12 r MTR(asym) in 1p/19q co-deleted gliomas (co-deleted, 1.17% +/- 0.32%; non-co-deleted, 1.72% +/- 0.41

13 gliomas (co-deleted, 1.17% +/- 0.32%; non-co-deleted, 1.72% +/- 0.41%, P = 1.13 x 10(-7)), while FDOP

14 Here, we employed CRISPR to delete a short interspersed nuclear element (SINE) in Ma

15 In a previous study, we deleted a gene (PG1780 in strain W83) predicted to encod

16 ed to explore the functional consequences of deleting a single conserved exon of PTCHD1-AS.

17 In a previous study of the effect of deleting a single proline residue in the FP of a demyeli

18 of Hensen's cells was observed when Jag1 was deleted after Hensen's cell formation at postnatal day (

19 Here, we conditionally deleted all three neurexin adhesion molecules from presy

20 By conditionally deleting all FIKK kinases combined with large-scale quan

21 By deleting all threonine deaminases, we generated a strain

22 tructural variation, in which rearrangements delete, amplify or reorder genomic segments that range i

23 activate the cas9 transgene (e-CHACRs) or to delete and replace the gene drive (ERACRs).

24 The BcJAR1 gene was deleted and its roles in fungal development and pathogen

25 Escherichia coli DeltaL YA, in which lacZ is deleted and lacY is retained, was employed to disable la

26 extran sulfate (AOM/DSS) exposure, both Xist-deleted and wild-type mice develop gastrointestinal tumo

27 recovered integrated vectors were partially deleted and/or rearranged.

28 Herein, we show that TDP-43-deleted astrocytes exhibit a cell-autonomous increase in

29 At the transcriptomic level, TDP-43-deleted astrocytes resemble A1-reactive astrocytes and i

30 r of residues driving amyloid formation upon deleting at least two repeats.

31 This study shows that deleting ATM in prostate cancer models does not signific

32 ential as iKOp/q mice generated on a Cacna1g deleted background show substantially diminished seizure

33 ression of a Bim mutant in which the CTS was deleted (BimL-dCTS) triggered apoptosis that correlated

34 Deleting both Fgf8 and Fgf20 results in kidney agenesis,

35 ents and, consequently, led to an internally deleted but partially functional protein.

36 we showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate

37 s with the most conserved genes of each step deleted, but also additional modifications are detected,

38 ) T cells in nonallergic individuals are not deleted, but have an expansion block that can be release

39 t tumor suppressors, they are rarely mutated/deleted, but rather are impaired by "inhibitor proteins.

40 nulosa cell expression of Runx2 and Cbfb was deleted by the Esr2Cre.

41 CRISPR knockout technique was used to delete c-Myc in primary murine lung ILC2 or an ILC2 cell

42 Restoration of the deleted C12L gene, encoding serine protease inhibitor 1,

43 ng fluorescently labelled wild-type and mecA-deleted CA-MRSA USA400 strains across ~57,000 compounds

44 Using genome editing to delete candidate REs, we showed that a strong intronic b

45 ifferentially expressed genes (DEGs) in Lmna-deleted cardiomyocytes.

46 Furthermore, in 14q-deleted ccRCC patients with complete (uncensored) surviv

47 nipulation, and the adverse prognosis of 14q-deleted ccRCC patients.

48 We used the CRISPR/Cas9 system to delete CD38 (CD38KO) in ex vivo expanded peripheral bloo

49 SINE-deleted cells exhibit an activated unfolded protein resp

50 By increasing serine biosynthesis, Max-deleted cells exhibit resistance to serine depletion.

51 Transcriptional profiling of RUNX1-CRISPR-deleted cells revealed a gene signature dominated by ext

52 Based on their replication ability in G3BP-deleted cells, Old World alphaviruses can be categorized

53 his model, we employed a genetic strategy to delete centrioles, the core structural components of the

54 1 affected neurons in vivo, we conditionally deleted (cKO) Top1 in postmitotic excitatory neurons in

55 Deleted clones exhibited an accessible chromatin conform

56 Removing this repression is important as deleting CNC1 allows enhanced cell growth under mild sta

57 und that a megabase-size "supermutation" has deleted color loci in green morphs.

58 ously uncharacterized virus gene, which when deleted completely attenuates the Georgia isolate.

59 interactions with BBDIs and genes that, when deleted, confer resistance.

60 he players can tune their playing period and delete connections by ignoring frustrating signals, to f

61 rial bioenergetics on neovascularisation, by deleting cox10 gene encoding an assembly factor of cytoc

62 collecting duct cells in which PKA has been deleted (CRISPR-Cas9) to identify PKA-independent respon

63 Skipping of exons 7 and 8 is predicted to delete critical amino acids in the ATP-binding site.

64 However, the pervasiveness of spurious and deleted cut sites in the raw data, which are called Rmap

65 tical mapping, which allows for spurious and deleted cut sites to be accounted for.

66 However, many cells with genetically deleted cyclin Ds, which activate and confer specificity

67 Deleting DDX11 in RPE1-TERT cells inhibits proliferation

68 better understand its cellular functions, we deleted DNA-PKcs from HeLa and A549 cells using CRISPR/C

69 Compared with FK506, GNF362 more selectively deleted donor alloreactive vs nominal antigen-responsive

70 g adolescence and are absent if the NMDAR is deleted during adulthood.

71 Mutants were constructed to delete each iron acquisition locus individually and in c

72 We deleted each of six commonly expressed bitter gustatory

73 Pax2 and Pax8 in the adult mouse kidney, we deleted either Pax2, Pax8, or both genes in adult mice a

74 task of defining its functions in cells, we deleted ELMOD2 in immortalized mouse embryonic fibroblas

75 axis promotes migration and invasion of PTEN-deleted endometrial tumor cells.

76 Deleting endothelial Slit2 suppressed metastatic dissemi

77 HP1gamma-deleted ESCs display reduced H3K36me3 enrichment, concom

78 HP1gamma-deleted ESCs have a slower self-renewal rate and an impa

79 utilize mammary cancer models to temporally delete essential autophagy regulators during carcinoma p

80 By deleting exon 13 (which encodes a sterile alpha motif) f

81 used a genetically engineered mouse model to delete exons 9/10 of Bcor (Bcor (DeltaE9-10) ) in GNPs d

82 l, we investigated the phenotypic impacts of deleting FATP2, followed by a transcriptomic analysis us

83 9-based engineering approach, we genetically deleted five large clusters of KRAB-ZFPs and demonstrate

84 In mice deleted for alphav integrin in the myeloid line to reduc

85 Agrobacterium tumefaciens strains either deleted for bioZ or which encode a BioZ active site muta

86 In SKPs deleted for Ccn2, differentiation into a myofibroblast,

87 Restoring glycerolipid synthesis in embryos deleted for CNEP-1 and ESCRT components rescued NE perme

88 were reduced in both HeLa and Jurkat T cells deleted for ESYT1 and ESYT2, SOCE was impaired only in J

89 Surprisingly however, mice deleted for Parkin alone are rather asymptomatic for PD-

90 es cerevisiae encoded by SIW14 Yeast strains deleted for SIW14 have increased levels of PP-InsPs.

91 A Staphylococcus aureus strain deleted for the c-di-AMP cyclase gene dacA is unable to

92 suggesting an association between altered or deleted forms of 8DR and virus attenuation.

93 Rejection also occurred if CXCR4 was deleted from donor Tregs pre-transplant.

94 we used conditional knockout mice with DORs deleted from forebrain GABAergic neurons (Dlx-DOR), and

95 Importantly, mice with IRF5 deleted from myeloid cells demonstrated T cell outcomes

96 block spanning Nppa-Nppb, respectively, were deleted from the mouse genome.

97 Importantly, deleting Fth in Sox10-positive oligodendroglial cells af

98 to interact with the receptor core, has been deleted, fully retain the ability to activate Src.

99 AAV vectors typically use a B-domain-deleted FVIII transgene, such as human FVIII-SQ in valoc

100 We demonstrate the utility of this model by deleting GALCLAMP1 specifically in myelinating Schwann c

101 Deleting Gata3 enhances adult prostate stem/progenitor c

102 The gene encoding ARF is the most commonly deleted gene in human cancer.

103 NKX3.1 is the most commonly deleted gene in prostate cancer and is a gatekeeper supp

104 gene and one of the most frequently mutated/deleted genes in human prostate cancer (PCa).

105 h low immune infiltrate had higher number of deleted genes while those with high immune infiltrate ex

106 (Xbp1) axis is blocked pharmacologically or deleted genetically have significantly reduced polarizat

107 a significantly lower MTR(asym) in 1p/19q co-deleted gliomas (co-deleted, 1.17% +/- 0.32%; non-co-del

108 In conclusion, 1p/19q co-deleted gliomas were less acidic, which may be related t

109 ing the Nkx2.1-cre mouse line we genetically deleted GluA1, GluA2, GluA3 selectively from MGE derived

110 In addition, genetically deleting GluN1 in dorsal root ganglion neurons or alpha2

111 Further, we determine that deleting GluN2D in the BNST leads to increased depressiv

112 hepatic functions of GPRC6A by conditionally deleting Gprc6a in hepatocytes by cross breeding Alb-Cre

113 In this study we conditionally deleted Hdac3 within Ctsk-expressing cells and examined

114 t such induction was abolished in HIF-2alpha-deleted hepatic MPhis.

115 PCBP1-deleted hepatocytes exhibited increased labile iron and

116 P that lacks hydroxylated prolines in ChREBP-deleted hepatocytes.

117 In contrast, deleting hmgR in two clinical isolates resulted in mutan

118 he effector proteins in the SidE family were deleted; however, this strain was still not targeted by

119 iled to rescue survival in the conditionally deleted iMEFs.

120 (AML), ALKBH5 was reported to be frequently deleted, implying a tumor-suppressor role.

121 The tumor suppressor CDK10 was deleted in 80% of the cohort while the oncogene MDM4 was

122 in which alpha2-Na/K ATPase is conditionally deleted in astrocytes display episodic paralysis.

123 Deleted in azoospermia-like (DAZL) is an RNA-binding pro

124 First, HIF-1alpha was constitutively deleted in CNS neurons (CNS-HIF-1alpha(-/-) ) by breedin

125 have revealed how netrin interacts with the deleted in colorectal cancer (DCC) receptor, other recep

126 Deleted in colorectal cancer (DCC), the receptor for the

127 The Deleted in Colorectal Carcinoma (Dcc) receptor plays a c

128 M2 was efficiently deleted in Cre-expressing cells, and the presence of lox

129 t mice in which a copy of the Arid1b gene is deleted in either parvalbumin (PV) or somatostatin (SST)

130 Second, when Xist is conditionally deleted in epithelial cells using Keratin14-Cre or in B

131 mouse in which the Cav1.2 alpha subunit was deleted in GFAP-positive astrocytes.

132 t mice, a single-cycle HSV candidate vaccine deleted in glycoprotein-D (DeltagD-2) that induces ADCC

133 Third, when Xist is deleted in gut using Villin-Cre, female mice remain heal

134 Purification and identification revealed deleted in malignant brain tumors 1 (DMBT1) (also known

135 The orthologous region was deleted in mice, which resulted in selective loss of exp

136 Because SNORD115 genes are deleted in most patients with the Prader-Willi syndrome

137 r mice in which the Tbk1 gene is selectively deleted in motor neurons, do not display a neurodegenera

138 esis was mitigated when Smad2 expression was deleted in neurons, supporting a role for the CX3CL1-TGF

139 Second, HIF-1alpha was deleted in NTS neurons in adult mice (NTS-HIF-1alpha(-/-

140 erritin heavy subunit (Fth) was specifically deleted in oligodendroglial cells.

141 mall hairpin RNA (shRNA) screen of 730 genes deleted in prostate cancer.

142 l of TSC (Tsc2-RG) in which the Tsc2 gene is deleted in radial glial precursors and their neuronal an

143 the NMDA receptor (NMDA-R) GluN1 subunit, is deleted in SCs.

144 ns, TCRalpha (TRAC) and TCRbeta (TRBC), were deleted in T cells to reduce TCR mispairing and to enhan

145 s includes a so far unknown ORF in the locus deleted in the FDA-approved oncolytic virus Imlygic.

146 was responsible for p53 activation, Atg7 was deleted in the presence or absence of the master regulat

147 d priming diminishes if Il7r is subsequently deleted in vivo.

148 anscription factors (TFs) among the 28 genes deleted in Williams syndrome, and prior mouse models of

149 L2HGDH was therefore co-deleted in ~ 95% of 14q deletions involving HIF1A locus.

150 is issue of Blood, Margraf et al selectively delete integrin linked kinase (ILK) in myeloid cells of

151 trand configuration normally provided by the deleted interswitch residues, thereby permitting homodim

152 Deleting IR-L in combination with IR-R synergistically t

153 Using this technology, we deleted IRF5 in human myeloid cells.

154 ated isolate OURT88/3 and an attenuated gene-deleted isolate, BeninDeltaMGF.

155 Murine-induced, Itpkb-deleted (Itpkb-/-) T cells attenuated acute GVHD in 2 mo

156 at beta-cells express abundant Kindlin-2 and deleting its expression causes severe diabetes-like phen

157 a BP180 functional-deficient mouse strain by deleting its extracellular domain of humanized NC16A (te

158 g Fgfr3-iCreER(T2) ::Jag1(loxP/loxP) mice to delete Jag1 at P0, we observed a similar loss of Hensen'

159 on induced by a live attenuated centrin gene-deleted L. donovani (LdCen(-/-) ) parasite vaccine.

160 fferent MBP-fused 5-HT(3A)-ICD constructs by deleting large segments of its amino acid sequence.

161 Deleting LATS kinases or expressing YAP variants that ev

162 ered regions (IDRs) of SRRM2 are genetically deleted, leads to a near-complete dissolution of NS.

163 Although PCBP1-deleted livers were iron deficient, dietary iron supplem

164 We deleted LKB1 from ISCs in mice using Lgr5-regulated CRE-

165 generate a mouse model of DCM in which they delete Lmna in cardiomyocytes and discover that bromodom

166 CD11b-cre transgenic mice were also used to delete Lpar1 in microglia.

167 ed a glycosylation site at residue 144 and a deleted lysine at position 147 residue were more effecti

168 analysis was performed, using CRISPR-Cas9 to delete MafK-int6 binding region in IRF8 expression-restr

169 We deleted mafr-1 from the Caenorhabditis elegans genome an

170 Silencing MR or deleting mannose residues on Env rescues Env expression

171 omic reduction of host brain excitability by deleting MapT suppressed molecular markers of epileptoge

172 overexpressing transgenic mice and Mcub gene-deleted (Mcub(-)(/-)) mice were generated to dissect the

173 Aberrant L1 integrations can delete megabase-scale regions of a chromosome, which som

174 of COX2 and PGE2 were also observed in NRF2-deleted melanoma cells in vivo.

175 We investigated the effects of deleting MHCII proteins specifically in mice with infect

176 Using this proline-deleted MHV strain, here we investigated whether intracr

177 tal muscle regeneration in both old and ARNT-deleted mice.

178 val time 2-fold in the myocyte-specific Lmna-deleted mice.

179 cell metabolism toward aerobic glycolysis by deleting mitochondrial pyruvate carrier recapitulates ag

180 These TbD1-deleted "modern" lineages are responsible for globally-s

181 We have deleted more than 250 acquired genes from 6 different lo

182 We conditionally deleted MORs from neurons in two key areas of the brains

183 In one, CRISPR/Cas9 deleted most of the Synpo gene, preventing production of

184 ster together along microtubules, while tail-deleted motors exhibit rapid motility without clustering

185 tion, which becomes severely reduced in tail-deleted motors.

186 Unchaperoned iron in PCBP1-deleted mouse hepatocytes leads to production of ROS, re

187 accelerates SCLC progression in an Rb1/Trp53-deleted mouse model.

188 We deleted mouse Nf1 from the medial ganglionic eminence, w

189 Ablation, the deleted mtDNA fraction, suffices to explain skeletal mus

190 luence hematopoietic aging, we conditionally deleted mTOR in ECs (mTOR(ECKO)) of young mice and obser

191 A VIG1-deleted mutant shows hypersensitivity to the translation

192 ) oligodendroglioma, IDH-mutant and 1p19q co-deleted (n = 81); (2) astrocytoma, IDH-mutant and 1p19q

193 Decreasing TG synthesis by deleting neuronal diglyceride acyltransferases (DGATs) a

194 ssfully rescued the migration defects of HuR-deleted neurons.

195 Deleting ngr1 in excitatory neurons in L4, but not in L2

196 Deleting NLRP3 inflammasome components or the downstream

197 Deleting Notch3 receptors on resident cells blunts kidne

198 pha subunit, deleting the HUbeta subunit, or deleting nucleoid-associated naRNAs, each previously imp

199 We examined the effect of deleting OCRL on endocytic traffic and cell division in

200 Individual mutants deleted of essential loci formed microcolonies of nongro

201 Here we find that mouse oocytes deleted of Setx accumulate DNA damage when exposed to ox

202 , we analyzed Caenorhabditis elegans mutants deleted of the sole SEIPIN gene, seip-1 Homozygous seip-

203 ative regulator phosphate and tensin homolog deleted on chromosome 10 (PTEN) in mural cells.

204 inhibition of phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a negative PI3K regulat

205 essor PTEN (phosphatase and tensin homologue deleted on chromosome 10) levels are frequently found re

206 Deleting one copy of Fgf8 reversed the effect of deletin

207 ting one copy of Fgf8 reversed the effect of deleting one copy of Spry1, which rescued the renal agen

208 Deleting one copy of the Tcf7 gene recapitulated Foxp3-d

209 Copy number aberrations (CNAs), which delete or amplify large contiguous segments of the genom

210 iR-146a is a known tumor suppressor commonly deleted or expressed at reduced levels in human myeloid

211 Deleted or inverted -31CBS impairs TAL1 expression in a

212 e transcription in time and space, we either deleted or inverted this sub-TAD boundary, eliminated th

213 (RBM10) is an RNA-binding protein frequently deleted or mutated in lung cancer cells.

214 ppressors, as they promote apoptosis and are deleted or mutated in many cancers.

215 Autism susceptibility increases when deleting or duplicating any point of pLI.

216 regret after posting on social media, and of deleting or editing their posts.

217 ic are these effects, when the tQCUG gene is deleted, or Elp3, the catalytic component of the Elongat

218 sed to produce an undetectable, N terminally deleted ORC5, the protein would lack 80% of the AAA+ ATP

219 Deleting P1 (DeltaP1) or both P1 and P2 (DeltaDelta) als

220 n geniculate neurons are cell autonomous, we deleted p75 specifically in Phox2b + oral sensory neuron

221 it the HCT116 colorectal cancer cell line to delete part of the hRpn13 Pru, producing cells that expr

222 created a LNJ-like protein in Arabidopsis by deleting parts of the coding sentence of the AFP2 gene t

223 cantly contribute to adult adipogenesis, and deleting Pdgfra in adult adipose lineage did not affect

224 We demonstrate that deleting PIR-A in the recipient or blocking PIR-A bindin

225 Here, we used CRISPR/Cas9 to delete PML and APB components from ALT-positive cells to

226 Surprisingly, deleting pmrB only partially suppressed qseC-related sha

227 Here we generated two mouse stains: one that deletes Podxl in developmentally mature podocytes (Podxl

228 w OTX2+ cell fates are regulated in mice, we deleted Prdm1 and Vsx2 or their cell type-specific enhan

229 a novel conditional knockout mouse model and deleted Prdm16 in adult mouse hematopoietic system using

230 Here, we show that deleting qseB completely reverses the shape defect of De

231 Here, we use G-deleted rabies virus-mediated monosynaptic tracing to id

232 ORC2 signaling was specifically disrupted by deleting rapamycin-insensitive companion of target of ra

233 We observed that the proline-deleted recombinant MHV strain is restricted to the opti

234 the initial system suffered from low yields, deleting redundant copies of tRNA(fMet) from the genome

235 that haploinsufficiency of genes within the deleted region drives the disorder.

236 (FOXI3), a candidate gene within the common deleted region found in patients, were compared with wil

237 Genomic location of the overlapping deleted region started from approximately 350 kb downstr

238 iency for FOXI3, a candidate gene within the deleted region, is the likely underlying cause.

239 A and assessed in full or by mutating and/or deleting regulatory elements by luciferase assays.

240 Depletion of cGMP by deleting retinal guanylate cyclase 1 or inhibition of PK

241 inated within the laminar circuitry of V1 by deleting separately in each cortical layer (L) a gene re

242 To our surprise, the majority of these deleted sequences did not integrate into the human genom

243 Our finding that massively deleted sequences rarely succeed in integrating has seve

244 n of pharmacologic and genetic approaches to delete SIGN-R1(+) marginal zone (MZ) macrophages and rev

245 orylation of LEF1 as well as HDAC1 among NLK-deleted SP CD8(+) cells.

246 enesis of the PCNA/Pol30 polymerase clamp or deleting specific error-prone polymerases abolishes the

247 an memory-decoding, enhancing, incepting, or deleting specific memories-suggests exciting therapeutic

248 ered mouse models where we can conditionally delete Stk11 and autophagy essential gene, Atg7, respect

249 A usp (4207)-deleted strain had rough colony morphology and reduced b

250 ignificantly affected processes in only CCC2 deleted strain.

251 Deleting such candidate TEs in human cells leads to the

252 First, when Xist is deleted systemically in post-XCI embryonic cells using t

253 Indeed, deleting Tbx1 triggers accelerated mineralization due to

254 nal KO line (GluN2D(flx/flx)) to selectively delete the subunit from the BNST, we find that BNST-GluN

255 We progressively deleted the distal carboxyl terminus domain (CTD) of the

256 storage in oligodendrocyte function, we have deleted the ferritin heavy chain (Fth) specifically in t

257 nic functions of LAR-RPTPs, we conditionally deleted the genes encoding all three LAR-RPTPs, singly o

258 generated mice with loxP-flanked Il11ra1 and deleted the IL11 receptor in adult fibroblasts (CKO mice

259 al function and target genes of such REs, we deleted the orthologue of an RE containing noncoding var

260 PR/Cas9 to generate a series of mutants that deleted the SE.

261 Deleting the canonical NF-kappaB kinase, IKKbeta, in Scx

262 Deleting the CC segment impaired BRD2's ability to resto

263 ted us to create an ERbeta knockout mouse by deleting the ERbeta gene with the use of CRISPR/Cas9 tec

264 Deleting the GAF domain from PtsP makes cells "blind" to

265 This process is circumvented by deleting the gene encoding cytochrome c (M) (CytM), a cr

266 Deleting the homologous gene in P. falciparum, PfDegP, s

267 oline residue (P63A) in the HUalpha subunit, deleting the HUbeta subunit, or deleting nucleoid-associ

268 ree systems but was enhanced over 10-fold by deleting the last 19 amino acids of the cytoplasmic tail

269 n young mice, while enhancing myelination by deleting the muscarinic acetylcholine receptor 1 in olig

270 cing a kinetically trapped analog of I(T) by deleting the N-terminal six amino acids increases the ag

271 Deleting the PCSK9 gene in mouse cancer cells substantia

272 ISPR)/Cas9 and non-homologous end-joining by deleting the repeat region, with the risk of creating in

273 such chromatin modification by conditionally deleting the Rnf40 subunit of the responsible E3 ligase

274 Knocking down the microRNAs or deleting their seed sites on Drd1 mimicked the cilia-bea

275 Deleting this motif from TraA abolishes the cell surface

276 and in vivo; (ii) an efficient mechanism for deleting this region from the viral genome may exist, gi

277 Here, we investigate the consequences of deleting this super-enhancer in vivo.

278 iorated nephritis, opposite of the effect of deleting Tlr9.

279 Blocking or deleting TNFR2 during sepsis decreased the susceptibilit

280 By deleting transcription cis-regulatory modules of one iTF

281 ion of Eif4e3, a neighboring gene, likely by deleting transcription start sites on the anti-sense str

282 orter, translational reporter and C-terminal deleted translational reporter lines in rice to establis

283 Deleting TRF2 (also known as TERF2) in somatic cells abo

284 Here, we conditionally deleted Trp53 (p53 hereafter) and/or the essential autop

285 f SOX9 was significantly increased in Hdac10-deleted tumor cells and depletion of SOX9 in Hdac10 knoc

286 at PTEN is expressed at lower levels in PTEN-deleted tumor samples than in normal solid tissue sample

287 denocarcinoma cells were increased in Hdac10-deleted tumors compared with Hdac10 wild-type tumors.

288 Deleting UPL3 depleted Sir2 during growth in rice cells,

289 However, when Cas3 and all crRNP genes were deleted, uptake of correctly processed spacers was obser

290 ild-type Smn (flwt-Smn) can be conditionally deleted using Cre recombinase.

291 Transcriptomic analyses of DICER1 deleted uteri or Ishikawa cells revealed unique transcri

292 Aberrant internally deleted viral RNAs (vRNAs) known as mini viral RNAs (mvR

293 gously to what is observed in vivo Massively deleted viral sequences formed more frequently in restin

294 Furthermore, infection with E1B55K-deleted virus resulted in an increased interaction of hn

295 geny production during infection with E1B55K-deleted virus.

296 model in which endothelial Dhh is inducibly deleted, we found that endothelial Dhh both opens the BB

297 ng recombinant VACV with A26L or G6R or both deleted, which increased virus replication levels and de

298 We deleted Yap/Taz throughout the palatal shelf mesenchyme

299 tochondria from TAZ-KO mouse cells and in CL-deleted yeast crd1Delta cells, indicating that the role

300 Here, we used CRISPR/Cas9 to delete ZNF274 binding sites at the SNORD116 locus to det