ライフサイエンスコーパス: deletion mutant

1 lysozyme with a higher catalytic rate double deletion mutant.

2 compared with infection with an isogenic hla deletion mutant.

3 A) mutant was stronger than that of the pulM deletion mutant.

4 M), but not to the wild-type or a fra island deletion mutant.

5 all five putative PFOR mutants and in a PFL deletion mutant.

6 find that slrA mRNA accumulated in the pnpA-deletion mutant.

7 iratory nitrate reductase activity in a mobA deletion mutant.

8 We further generated a lon-2 deletion mutant.

9 e diploid strains that are homozygous double-deletion mutants.

10 ds to moderate toxicity and the emergence of deletion mutants.

11 to improve the respiration capacity of CCC2 deletion mutants.

12 assays and in vivo growth phenotypes of gene deletion mutants.

13 segment and the attenuated phenotype of NSs deletion mutants.

14 ful, although there have been successes with deletion mutants.

15 ions, we utilized c-di-GMP regulatory enzyme deletion mutants.

16 lex by using CRISPR/Cas9, and obtained three deletion mutants.

17 nt phenotypes in kn1 missense and tm1081(lf) deletion mutants.

18 n and striatal spinogenesis defects of Foxp2-deletion mutants.

19 this surface shell of [PSI+] deposits in the deletion mutants.

20 esis of strain 4295, which consists of three deletion mutants.

21 investigate this region with a panel of LANA deletion mutants.

22 ssing either wild-type NSP5 or selected NSP5 deletion mutants.

23 Using a double-deletion mutant (12203) of CPXV, we show that direct pri

24 n IgM ligand binding in the cytoplasmic tail-deletion mutant, 2) enhanced cap formation in FcmuR upon

25 By generating a series of deletion mutants, a conserved 69-residue (Asn(81)-Asn(14

26 The pvdO deletion mutant accumulates dihydropyoverdine, and this

27 cell function, we analyzed how an endogenous deletion mutant affected Pdx1 expression embryonically a

28 Using a systematic series of deletion mutants (all containing the intact DNA-binding

29 ese proteins we generated mice with targeted deletion mutant alleles of Tmc6 or Tmc8 Either TMC6 or T

30 Genetic analysis of DNA methyltransferase deletion mutants also indicated that proper reprogrammin

31 We further generated a lon-1 deletion mutant and an isogenic complemented strain.

32 We constructed an efbA deletion mutant and demonstrated that its virulence was

33 Analysis of a slr1270 insertion deletion mutant and respective wild-type revealed that t

34 Successful generation of a BbhtrA deletion mutant and restoration by genetic complementati

35 sis genes were still transcribed in the cccA deletion mutant and the quinol oxidase genes (cioAB) wer

36 111 and C112, in domain B and found that the deletion mutants and a double mutant lacking the C94-C11

37 s, LtgG (BPSL3046) through the generation of deletion mutants and biochemical analysis.

38 Using HDAC5 deletion mutants and co-immunoprecipitation studies, we

39 racellular and surface-associated capsule in deletion mutants and complemented strains further implic

40 screened Keio collection of Escherichia coli deletion mutants and revealed that deleting genes for re

41 Experiments with deletion mutants and synthetic peptides revealed that am

42 d characterized sncRNA species from two ABI3 deletion mutants and the wild type P. patens that were s

43 RD2 were assessed by comparing parental, RD2 deletion mutant, and complemented mutant serotype M28 GA

44 ion for the hypomorphic phenotype of the CTR-deletion mutant, and further suggests that Reln mutation

45 several variants of p53 and SUMO1, including deletion mutants, and those with modified sequences cont

46 he yeast Saccharomyces cerevisiae, coq1-coq9 deletion mutants are respiratory-incompetent, sensitive

47 CKS1 deletion mutants are severely impaired in hyphal growth,

48 ves an essential function in vivo, as bb0405-deletion mutants are unable to transmit from ticks and e

49 ar to the Etl4(lacZ) and Skt(Gt) alleles our deletion mutants are viable and fertile and show only mi

50 ern of yeast Pex11 in all non-essential gene deletion mutants, as well as in temperature-sensitive es

51 wine fever virus (ASFV) isolate OURT88/3 and deletion mutant BeninDeltaMGF have previously been shown

52 etermined that in cells infected with an NS4 deletion mutant (BTV8DeltaNS4), there is increased synth

53 vivo Secretion was impaired in a propeptide-deletion mutant but could be restored by co-expression o

54 if-derived peptide mirrors the effect of IQ3 deletion mutant by reducing Akt activation but has no im

55 SH2) or phosphotyrosine-binding (PTB) domain deletion mutants by biolayer interferometry, revealing t

56 ed cells infected with each of the five VMAP deletion mutants by electron tomography, which is necess

57 analyzed the functionality of several CCBE1 deletion mutants by generating knock-in mice expressing

58 , our functional rescue experiment using Jpx-deletion mutant cells shows that human JPX can functiona

59 LN3(R334C) and for a JNCL-related C-terminal deletion mutant (CLN3DeltaC).

60 icrobeads loaded with CASPR2, but not with a deletion mutant, co-localize with transfected CNTN1, sug

61 sources, such as ORFeome clone libraries and deletion mutant collections, are fundamental tools for e

62 Furthermore, an mrpJ deletion mutant colonized the bladders of mice at signif

63 and transcriptome were altered in the sdg8-5 deletion mutant compared to wild type, within the contex

64 ted (ATG) gene MoATG4, was altered in MoHMT1 deletion mutants, compared with wild-type strains under

65 The analysis of in frame deletion mutants confirmed the role of a hydroxymethylgl

66 In supporting its repressive role, the mcrA deletion mutant conidia contain more amounts of sterigma

67 The crystal structure of delta(1-101) (a deletion mutant containing the first 101 amino acid [aa]

68 Furthermore, SRSF1 deletion mutants containing the protein RNA-binding doma

69 ential for StAR activity, and the N-terminal deletion mutant continued to interact with VDAC2.

70 nd a monomeric CaMKII oligomerization-domain deletion mutant control.

71 immunoreactivity against a series of PLA2R1 deletion mutants covering the extracellular domains.

72 eq) screening of a pooled collection of gene-deletion mutants cultivated as biofilm and planktonic ce

73 A deletion mutant, DeltaalyA1, grew as well as the wild ty

74 The Clg2p deletion mutant (DeltaClg2p) had altered appressorium fo

75 A M. tuberculosis cytochrome bd oxidase deletion mutant (DeltacydKO) was hyper-susceptible to co

76 The FgSCH9 deletion mutant (DeltaFgSch9) was defective in aerial hy

77 The FgVPS27 deletion mutant (DeltaFgvps27) exhibited a reduction in

78 any effect on virus production; however, the deletion mutant (DeltaG209) showed a very low titer when

79 Here, we synthesize a single deletion mutant, DeltaG25, with the aim of sterically hi

80 d with familial frontotemporal dementia, the deletion mutant DeltaK280 and the point mutant P301L.

81 e NDH-2s in Synechocystis, by constructing a deletion mutant (DeltandbC) for a corresponding protein

82 old or more) up- or down-regulated in a scmR deletion mutant (DeltascmR) Metabolically, the DeltascmR

83 The deletion mutant DeltaSho1 was incubated on a cellophane

84 Although an SsrA-deletion mutant (DeltassrA) colonized the host to a norm

85 nning and mapping experiments with LptD-loop-deletion mutants demonstrated that 7 of the 13 ECLs are

86 The analysis of deletion mutants demonstrated that the globular domain a

87 in a moderate to severe growth phenotype in deletion mutants, demonstrating a key role for each enzy

88 An Mtb rv0888 deletion mutant did not grow on sphingomyelin as a sole

89 The IIV6 340R deletion mutant did not have a replication defect in cel

90 RPA0376 and RPA2838 single- and double-deletion mutants did not differ in longevity from WT R.

91 C. elegans intestinal epithelium, and sdpn-1 deletion mutants display phenotypes indicating a block i

92 AaGPx3 deletion mutants displayed increased sensitivity to H2 O

93 efficient transformation in vitro An EBNA3A deletion mutant EBV strain was recently reported to esta

94 nuclear localization of the PA-X C-terminal deletion mutant enhanced shutoff activity, highlighting

95 The SAM domain deletion mutant, EphA2DeltaS-GFP, also underwent further

96 Deletion mutants exhibited a range of translational phen

97 C-terminal deletion mutants exhibited a reduced tendency to solubil

98 In this study, we found that rcan-1 deletion mutants exhibited cryophilic behavior dependent

99 yl-terminal GPI anchor, while the GPI anchor deletion mutant exhibits dominant negative activity and

100 C. albicans sap6 deletion mutants failed to accumulate intracellular zinc

101 In addition, SYNV M deletion mutants failed to exclude superinfection by wil

102 osa, and compared the wild-type strains with deletion mutants for crc.

103 ened the genome-wide library of viable yeast deletion mutants for defects in the degradation of corti

104 We produced isogenic deletion mutants for every S. epidermidis psm locus and

105 ll extremities, whereas in anucleated cells (deletion mutants for mukB), the Tsr clusters are closer

106 n of Tsr clusters at the poles is smaller in deletion mutants for Tol-Pal than in wild-type cells, al

107 Here, we designed a HOTAIR deletion mutant form, named HOTAIR-sbid, including the p

108 We constructed a sdeXY deletion mutant from a derivative strain of the clinical

109 ng prompted us to generate a series of Mcl-1 deletion mutants from both the N and C termini of the pr

110 d approach, this method allows us to combine deletion mutants from different experiments and sources.

111 h phase are elucidated for seven single gene deletion mutants from upper glycolysis, pentose phosphat

112 sembly and function in strains in which loop deletion mutant genes are the ONLY: sources of uL4 or uL

113 Individual scfCDE deletion mutants grew comparably to WT 5448 in rich medi

114 When the deletion mutant grown at 28 degrees C was examined by EM

115 , a non-H5N1-NS1 [H6N6-NS1(E71)], and the LR deletion mutant H6N6-NS1(Delta80-84/E71) mimicking the m

116 The selD CRISPR deletion mutant had a growth defect in protein-rich medi

117 The FgSSN3 deletion mutant had a nutrient-dependent growth defects

118 g device-associated infection, the total psm deletion mutant had a significant defect in disseminatio

119 ssion of the C-terminal (amino acid 362-396) deletion mutant had no effect.

120 The Fgprp4 deletion mutant had severe growth defects but often prod

121 sion electron microscopy studies of two VMAP deletion mutants had suggested retention of connections

122 In corticosteroid-treated mice, a DeltacalA deletion mutant has significantly attenuated virulence r

123 While profound attenuation of ICP34.5 deletion mutants has been repeatedly demonstrated, a rol

124 We showed that the deletion mutants have increased binding to human-like re

125 e strategy for Burkholderia, but single-gene-deletion mutants have not provided complete protection.

126 We constructed a pil3 deletion mutant in a Pil3 overexpressing variant (Pil3+)

127 An ESX-5a deletion mutant in the model system M. marinum backgroun

128 Moreover, a M. tuberculosis H37Rv deletion mutant in the Rv3134c-dosS-dosR regulon, formed

129 verall, as the first report of targeted gene deletion mutant in U. virens, our results showed that Uv

130 c suppressor mutant of the priA beta-hairpin deletion mutant in which 22 codons around the deletion s

131 ry S. epidermidis psm locus and a sequential deletion mutant in which production of all PSMs was abol

132 oled diverse transcriptionally barcoded gene deletion mutants in 11 different environmental condition

133 from FMN-hydroquinone to its partners, three deletion mutants in a conserved loop near the FMN were c

134 These are the first reports of Pfhrp2/3 deletion mutants in Angola.

135 C. elegans, we utilized the individual gene deletion mutants in E. coli (K12).

136 By combining expression of GFP-JPH1 deletion mutants in skeletal muscle fibers with in vitro

137 ecular analyses using defined virulence gene deletion mutants in that lineage as of yet.

138 plied our method to a set of newly generated deletion mutants in the dioecious plant Silene latifolia

139 Plant inoculation experiments with deletion mutants in the individual genes (Deltaexlx and

140 Four single deletion mutants in ttn.2 or ttn.1 resulted in four phen

141 he expression of a CD81 carboxy (C)-terminal deletion mutant, increases cellular dNTP content and HIV

142 production of 128 proteins in the oxyR gene deletion mutant, indicating its global regulatory role i

143 phenotype is similar to that of MGAS5005 sse deletion mutants, indicating that the enzymatic activity

144 An E3 deletion mutant induced protein kinase R (PKR) and eukar

145 Infection of Swiss cells with an EHEC espW deletion mutant induces a cell shrinkage phenotype that

146 nd unable to synthesize Q(6) The yeast coq10 deletion mutant is also respiratory-deficient and sensit

147 Regulation of a CLH-3b AD deletion mutant is reconstituted by intracellular perfus

148 trate that an Mtb cytochrome bc1-aa3 oxidase deletion mutant is viable and only partially attenuated

149 ve form of CotH, like those formed by a cotG deletion mutant, lack the pattern of electrondense outer

150 red in two independent cerk1 null mutants; a deletion mutant lacking D14L, and with D14L complemented

151 We investigated a deletion mutant lacking only this alpha-helix in stable

152 We then constructed two deletion mutants lacking C-terminal regions and mutants

153 s less constrained, whereas in the D219/E220 deletion mutant, little orientational preference was obs

154 An IQ3 deletion mutant loses interactions with the PI3K-Akt com

155 then crossed these animals with the NDL (Neu DeLetion mutant) model of ErbB2-induced mammary tumorige

156 The MoSYN8 deletion mutant (Mosyn8) mutant exhibits defects in endo

157 he BERosome complex, as observed for a NEIL1 deletion mutant (N311) lacking the CTD, not only inhibit

158 er associated with the generation time of RP deletion mutants nor with bulk inhibition of protein syn

159 We therefore generated a cytoplasmic deletion mutant of CD27 (CD27-trunc) to study the role o

160 A defined deletion mutant of cysE was attenuated in C57BL/6 wild-t

161 Mapping of digenic interactions for a deletion mutant of each paralog, and of trigenic interac

162 A deletion mutant of EZH2, lacking its N-terminal domain,

163 ransgenic plants expressing the F-box domain deletion mutant of FOF2 (FOF2DeltaF), or double loss of

164 We created a markerless deletion mutant of fsq and demonstrate that fsq is requi

165 endotoxicity and CAMP resistance of a double deletion mutant of lpxE-eptA was similar to that of a si

166 Herein, a deletion mutant of MAB_4780, encoding a dehydratase, dis

167 A quadruple deletion mutant of PpCSP1 and three closely related PpCS

168 Moreover, a deletion mutant of rovA, previously shown to be moderate

169 An FnBPB-deletion mutant of S. aureus LAC bound less H3 and was m

170 -in-oil-adjuvanted, formalin-inactivated hha deletion mutant of Shiga toxin 2 negative (stx2(-)) O157

171 with PTEN for binding to DLG-1, unlike a PBM deletion mutant of Tax1.

172 in the absence of ligands, and a well folded deletion mutant of the Bacillus stearothermophilus enzym

173 Here, an open reading frame 2 deletion mutant of the neuropathogenic EHV-1 strain Ab4

174 riments with coilin-deficient plants and the deletion mutant of the TRV 16K protein showed that both

175 As expected, the A6 deletion mutant of VACV failed to replicate in noncomple

176 ed metabolomics analysis of an S. cerevisiae deletion mutant of YDR109C revealed ribulose as one of t

177 he homologous pathway in RHA1 was confirmed: Deletion mutants of agcA and aphC, encoding the meta-cle

178 pproach to produce a library of >9000 random deletion mutants of an artificial RNA ligase enzyme repr

179 We show that spoIIQ or spoIIIAH deletion mutants of C. difficile result in anomalous eng

180 We made single and double deletion mutants of ccmK3 and ccmK4 in Synechococcus elo

181 By contrast, deletion mutants of gcoA and pcaL, encoding a CYP255A2 f

182 lting in reduced nucleosome-barrier, such as deletion mutants of histones H3/H4 themselves and the ge

183 characteristics, and produced isogenic gene deletion mutants of important CA-MRSA virulence determin

184 In an application to data from deletion mutants of kinases and phosphatases in S. cerev

185 We examined deletion mutants of luxO, opaR, and aphA for in vivo fit

186 By screening a panel of deletion mutants of mouse cytomegalovirus (MCMV) a mutan

187 While studying C-terminal (C-tail) deletion mutants of Mtf1 and TFB2M, we stumbled upon a f

188 A recent study by Laplante et al.[3], using deletion mutants of myp2 and myo51 and the mis-sense mut

189 In contrast, movement of recombinant MP deletion mutants of sonchus yellow net nucleorhabdovirus

190 tion of the mammalian host by using unmarked deletion mutants of the F. tularensis live vaccine strai

191 Deletion mutants of the S1242, S1289, S2406 and icsA gen

192 Deletion mutants of the seven genes within one LSR (G-LS

193 ith the use of motile and isogenic nonmotile deletion mutants of two independent strains of P. aerugi

194 Deletion mutants of ULS1 are hypersensitive to the Top2

195 Deletion mutants of unc-68, and in particular the point

196 Among various deletion mutants, only full-length Mdm4 was able to supp

197 atory imbalances that are not uncovered from deletion-mutant phenotyping.

198 f TdDof restored stem solidness in the TdDof deletion mutant pithless1 and conferred stem solidness i

199 paring parental B. pertussis to an rseA gene deletion mutant (PM18), we sought to characterize the ro

200 Most interestingly, the deletion mutant possessed a higher thermal stability and

201 We tested several candidate miRNA-deletion mutants post gamma-irradiation and identified c

202 ygen-dependent alginate synthesis inhibitor) deletion mutant produced alginate also in the presence o

203 showed that inoculation with a DeltaprrF1,2 deletion mutant protects against future challenge with w

204 Herein, using has deletion mutants, quantitative PCR analyses, and immunob

205 In this study, we showed that the Fgsrp1 deletion mutant rarely produced conidia and caused only

206 The seip-1 deletion mutants reduced the ratio of polyunsaturated fa

207 on of the NCR169 gene into the dnf7-2/NCR169 deletion mutant restored symbiotic nitrogen fixation.

208 Phenotyping of Mtb hadD deletion mutant revealed the influence of HadD(Mtb) on t

209 Phenotypic analysis of TF deletion mutants revealed complex relationships among vi

210 plementation experiments performed with PstP deletion mutants revealed marginally compromised surviva

211 , a nonbiased screen of transcription factor deletion mutants revealed that the phosphate-responsive

212 h cDNA clone of SL-CoV WIV1 (rWIV1), an ORFX deletion mutant (rWIV1-DeltaX), and a green fluorescent

213 The deletion mutant showed a reduction in transcription of g

214 An alc deletion mutant showed modified cell morphology when gro

215 e corresponding C. elegans clec-49 and fat-3 deletion mutants showed delayed biofilm formation and ab

216 of CSQ1 or a C-terminal (amino acid 388-396) deletion mutant significantly promoted the association o

217 A MakatG1 deletion mutant strain (DeltaMakatG1) showed decreased c

218 An ibeA deletion mutant strain (NRG857cDeltaibeA) was constructe

219 e, a yeast (Saccharomyces cerevisiae) SEIPIN deletion mutant strain and a plant (Nicotiana benthamian

220 s of a wild-type strain and an isogenic fabT deletion mutant strain found that between 3.7 and 28.5%

221 of both the reference strain and homozygous deletion mutant strain of CCC2, which encodes a Cu(2+)-t

222 strain; in situ reconstitution of fnm in the deletion mutant strain restored adherence.

223 ocA polymorphisms (n = 48), an isogenic rocA deletion mutant strain, and five isogenic rocA polymorph

224 Here we generate a new deletion mutant strain, CVS-N2c(DeltaG), and examine its

225 n-independent growth of the M. smegmatis tam deletion mutant strain.

226 m were significantly upregulated in the fabT deletion mutant strain.

227 h more resistant to oxidants than a catalase-deletion mutant strain.

228 Individual DeltatrxA and DeltatrxC deletion mutant strains each show a greater abundance of

229 surface in both the E. coli parent and aceE deletion mutant strains.

230 s of lipid A isolated from the corresponding deletion mutant strains.

231 ties identical to those of the corresponding deletion mutant strains.

232 nalyses of ert-m and ant1 single- and double-deletion mutants suggest Ant1 as a closely linked gene e

233 examination of the inferred fitness of gene deletion mutants suggests that secondary replicons evolv

234 geneity was more pronounced in the D219/E220 deletion mutant than in the E220A mutant, indicating tha

235 rm switching is more prominent in the sdg8-5 deletion mutant than in the wild type.

236 ion of wild-type Pdcd4 and Pdcd4(157-469), a deletion mutant that binds to translation initiation fac

237 tive PARP6 mutant, or a cysteine-rich domain deletion mutant that has significantly reduced catalytic

238 himeric dimers of aS (syn-syn) and by the aS deletion mutant that lacks the C-terminus, i.e., aS (1-9

239 Having generated an R. gnavus nan-cluster deletion mutant that lost the ability to grow on sialyla

240 We identified 56 diverse E. coli deletion mutants that enhance dauer formation in an insu

241 ichia coli collection and uncovered 244 gene deletion mutants that slow Caenorhabditis elegans develo

242 Additionally, degron deletion mutants that upregulate Pyr exhibit cell polari

243 Also in deletion mutants, the distribution of Tsr clusters diffe

244 ts of wild-type or an isogenic typhoid toxin deletion mutant (TN) of S. Typhi.

245 These six basic amino acids enabled a PA deletion mutant to suppress protein expression at a leve

246 eficient EBOV VP40 double PTAP/PPEY L-domain deletion mutant to wild-type levels.

247 ucted a high-density Y-deletion map and used deletion mutants to manipulate gene dose and analyze gen

248 ival, as determined by the inability of vapA deletion mutants to replicate in host macrophages.

249 Subsequently, we subjected deletion mutants to suboptimal temperatures that are kno

250 tion of ace to be virtually absent in a grvR deletion mutant under the conditions that increase ace e

251 ng cariogenic traits and strain fitness in a deletion mutant using in vitro biofilm models.

252 this question, we generated a complete tarP deletion mutant using the fluorescence-reported allelic

253 fined using a series of alanine scanning and deletion mutant variants.

254 I2 and allowed construction of the VACV I2L deletion mutant vDeltaI2.

255 n of ECTV-resistant C57BL/6 mice with a CrmD deletion mutant virus resulted in uniform mortality due

256 , using monoclonal antibody inhibition and a deletion mutant virus, we demonstrate that the KSHV viri

257 density and the infectivity of a class II IN deletion mutant virus.

258 e present a novel approach that employs HCMV deletion mutant viruses lacking HLA class I immunoevasin

259 id of transport activity, but remarkably the deletion mutant was active, as were mutants obtained by

260 One Uvhog1 deletion mutant was identified after screening over 600

261 A pglA deletion mutant was impaired in both pathogenesis and gu

262 A lipA lipB deletion mutant was more sensitive than the wild-type pa

263 The amd1 deletion mutant was normal in growth and conidiation but

264 . marcescens strain and found that the sdeXY deletion mutant was sensitive to a broad spectrum of ant

265 The asp f3 deletion mutant was sensitive to ROS, and this phenotype

266 Furthermore, we showed that each deletion mutant was significantly attenuated in comparis

267 Importantly, we showed that pil3 deletion mutant was unable to colonize mice colon as com

268 GABA-induced transport currents by all three deletion mutants was diminished, and the charge-to-flux

269 n, and that the survival of prophenoloxidase-deletion mutants was impaired when fed several plant phe

270 For all four deletion mutants we find that NO-induced biomass reducti

271 negatively charged residues of the D219/E220 deletion mutant, we measured more unfavorable entropic a

272 Also, using a wbaP(Mx) deletion mutant, we revisited the role of LPS O-antigen

273 yces cerevisiae) vps23Delta bro1Delta double-deletion mutant, we showed that the Vps23p ESCRT-I prote

274 protein-tagged components or from different deletion mutants, we determined the molecular architectu

275 y characterizing a series of PA-X C-terminal deletion mutants, we found that the first 9 amino acids

276 the motor structures of wild-type and stator-deletion mutants, we not only localized the stator compl

277 Furthermore, by imaging deletion mutants, we observed functional differences bet

278 Through a systematic analysis of F-box deletion mutants, we show that Dia2 is required to susta

279 chemical and crystallographic analysis of HD deletion mutants, we show that the HD is an autoinhibito

280 hese chromosomal mutations as well as a pslG deletion mutant were still capable of forming Psl biofil

281 ominently increased replication of the SPI-1 deletion mutant were subjected to a secondary screen.

282 We found that all deletion mutants were capable of forming caffeine- and r

283 bpsl2248, tex, rpiR, bpsl1728, and bpss1528 deletion mutants were constructed from the wild-type str

284 ine how eIF4G recruits the mRNA, three eIF4G deletion mutants were constructed: (i) eIF4G601-1196, co

285 The hptA, hptRS, and uhpT markerless deletion mutants were generated by an allelic replacemen

286 Both deletion mutants were much more sensitive to O2-mediated

287 phenocopies that of ISC1 Reciprocally, ISC1 deletion mutants were sensitive to benomyl, indicating a

288 The N1, N2, N4, and N5 deletion mutants were significantly impaired in T4P-medi

289 Twelve single gene deletion mutants were under selection in this assay, and

290 Isogenic P1 deletion mutants were used to reconstitute the previousl

291 interaction and functional analyses of XND1 deletion mutants were used to test the importance of RBR

292 NB-B), and here, we characterize a recurrent deletion mutant where the last 14 residues are missing.

293 n of P. patens PpMET we generated DeltaPpmet deletion mutant which lost (m)CG and unexpectedly (m)CCG

294 ortant for virulence, we created a Deltacps1 deletion mutant which was unable to cause disease in thr

295 not essential for virulence, because the Mip deletion mutant, which failed to form dimers, was still

296 he thermosensitive growth of the yeast mms19 deletion mutant while expression of the diminutive allel

297 We identified two HSV-1 ICP27 amino-terminal deletion mutants with a similar release defect.

298 A comparison of the binding of eIF4G deletion mutants with BTEs containing mutations showed a

299 Four deletion mutants with reduced cytotoxicity were identifi

300 into a pool of 4653 homozygous diploid yeast deletion mutants with unique barcode sequences, followed