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1 iple sclerosis pathology outside the classic demyelinating lesion.
2 acid (ACPD), was therefore injected into the demyelinating lesion.
3 injected with lysolecithin to induce a local demyelinating lesion.
4 s the effects of a single acute inflammatory demyelinating lesion.
5 associated inflammation and the formation of demyelinating lesions.
6 ntributors to thalamic atrophy than thalamic demyelinating lesions.
7 ), and this synaptic loss extends far beyond demyelinating lesions.
8 g myelination that is often stalled at human demyelinating lesions.
9 cross the blood-brain barrier, resulting in demyelinating lesions.
10 ises the regenerative response to subsequent demyelinating lesions.
11 R4.1 immunoreactivity is retained or lost in demyelinating lesions.
12 es at the rim of chronic active white matter demyelinating lesions.
13 reactive astrocytes in both rodent and human demyelinating lesions.
14 ursor cells with the distinct environment of demyelinating lesions.
15 early axonal pathology outside inflammatory demyelinating lesions.
16 the maturation of OPCs that are recruited to demyelinating lesions.
17 ons support using MTR to monitor symptomatic demyelinating lesions.
18 rocytes and Schwann cells, and recovery from demyelinating lesions.
19 ver-ground locomotion in the adult rat using demyelinating lesions.
20 ukin (IL)-18 and IFN-gamma were expressed in demyelinating lesions.
21 ed mononuclear phagocytes in and adjacent to demyelinating lesions.
22 EV was found predominantly on macrophages in demyelinating lesions.
23 lized with viral RNA and was associated with demyelinating lesions.
24 4AP) can sometimes cause ectopic activity in demyelinating lesions.
25 s decreased with onset-age, whereas actively demyelinating lesions and compartmentalized inflammation
26 e into oligodendrocytes limits the repair of demyelinating lesions and contributes to the disability
28 osaminoglycan hyaluronan (HA) accumulates in demyelinating lesions and has been implicated in the fai
31 ation and neuropathology in inflammatory and demyelinating lesions, and reduced paralysis in a mouse
32 oth 'virtual' and real) at an early stage of demyelinating lesions, and several groups, including our
33 loped neither neuropathological symptoms nor demyelinating lesions, and SJL P1-Tg mice developed sign
34 is (MS), axonal injury precedes inflammatory demyelinating lesions, and the distribution of axonal da
36 r Th cells that can drive the development of demyelinating lesions are phenotypically diverse or aris
37 croglia and foamy macrophages present within demyelinating lesions as well as in perivascular infiltr
41 dicate that BDNF may play a role following a demyelinating lesion by regulating the numbers of progen
42 Here, we developed a method to label CNS demyelinating lesions by the intraperitoneal injection o
43 g mechanisms for PIRA include chronic-active demyelinating lesions (CALs), subpial cortical demyelina
44 Local increases in BMPs at the site of a demyelinating lesion causes upregulation of gliosis, gli
45 of CPS by making unilateral electrolytic or demyelinating lesions centered on the spinothalamic trac
46 s delayed significantly in response to focal demyelinating lesions compared with wild-type animals.
47 S autoimmunity characterized by inflammatory demyelinating lesions confined to optic nerves and spina
48 sulfate proteoglycans (CSPGs) accumulate at demyelinating lesions creating a nonpermissive environme
49 ies and 32 autopsies that contained actively demyelinating lesions defined by stringent criteria.
55 onounced acute axonal damage in inflammatory demyelinating lesions from children compared to adults.
56 on myelin-laden macrophages in eight active demyelinating lesions from four autopsied multiple scler
57 ination were identical among multiple active demyelinating lesions from the same individual, but diff
58 d dorsal column of adult rats in which focal demyelinating lesions had been produced using ethidium b
59 oligodendrocyte differentiation following a demyelinating lesion, however, the endogenous sources of
60 pable of myelinating axons, are preserved in demyelinating lesions; however, why these precursors do
61 e B cells in vivo increased fourfold after a demyelinating lesion in corpus callosum, indicating that
65 yelin formation, but their role in repair of demyelinating lesions in diseases such as multiple scler
67 these macrophages to extensive inflammatory demyelinating lesions in infected SHP-1-deficient mice.
68 omyelitis (TMEV-DA) virus induces persistent demyelinating lesions in mice and serves as a model for
69 ling is activated in oligodendrocytes within demyelinating lesions in multiple sclerosis and EAE.
73 MEV but receiving no RCA I, had inflammatory demyelinating lesions in the anterior/lateral funiculi.
74 ignificantly higher viral loads and apparent demyelinating lesions in the central nerve system (CNS)
75 us (TMEV), results in immune system-mediated demyelinating lesions in the central nervous system (CNS
81 s to infiltrating T cells and macrophages in demyelinating lesions, it is also possible that astrocyt
82 ter cuprizone treatment, suggesting that the demyelinating lesion itself elicits a decrease in BDNF.
83 ntrols, we examined the relationship between demyelinating lesion load in three volumes of the cerebr
84 system (CNS) characterized by inflammatory, demyelinating lesions localized in the brain and spinal
85 rian degeneration of axons transected in the demyelinating lesions makes a major contribution to the
87 Acute optic neuritis due to an inflammatory demyelinating lesion of the optic nerve is often seen in
89 ells in perivascular cuffs and inflammatory, demyelinating lesions of SJL mice chronically infected w
90 drocyte progenitor cells (OPCs) recruited to demyelinating lesions often fail to mature into oligoden
91 y should be considered for acute tumefactive demyelinating lesions only once criteria of disseminatio
92 ssion in healthy control brain in all active demyelinating lesions, remyelinated lesions, and peripla
93 ia consisted of the presence of early active demyelinating lesions--required for immunopattern classi
95 e plus photon irradiation producing discrete demyelinating lesions sufficient to stop axonal conducti
96 t and topography of OG destruction in active demyelinating lesions suggests that in subsets of multip
98 aptic morphological abnormality secondary to demyelinating lesions that are in an anatomically linked
99 e the roles BDNF may play in the repair of a demyelinating lesion, the cuprizone model was used and t
100 ical relapses and the formation of new focal demyelinating lesions; they lead to neuroaxonal dysfunct
101 oligodendrocytes during the progression of a demyelinating lesion to a chronic state and determined w
102 ats with focal dorsal column inflammatory or demyelinating lesions to determine whether DTI measures
103 ptimal spatiotemporal positioning of OPCs in demyelinating lesions to receive local proliferative and
104 lt in selective localization of inflammatory demyelinating lesions to the optic nerves and spinal cor
105 ied to identify and characterize the primary demyelinating lesion, using a variety of histological an
106 main questions: (i) is the hypoxia found in demyelinating lesions 'virtual' or real; (ii) what cause
107 Importantly, in adults, remyelination of demyelinating lesions was also accelerated, at the expen
108 at recapitulates focal cerebral inflammatory demyelinating lesions, we investigated whether MRI is se
109 enters the spinal cord and colocalizes with demyelinating lesions, we used ultrasmall superparamagne
111 ith early-stage multiple sclerosis, cortical demyelinating lesions were frequent, inflammatory, and s
115 d do not mature into myelin-forming cells in demyelinating lesions where HMW hyaluronan is present.
116 in mice, with hiNSCs persisting long-term in demyelinating lesions where they can produce graft-deriv
117 ng ages, including acute and chronic, active demyelinating lesions with macrophages and lymphocytic p
119 ar syndrome) and at least two characteristic demyelinating lesions within the brain were randomized t