ライフサイエンスコーパス: densely

1 e, and provided position-selective access to densely 1,2,3-substituted arenes, which are not viable b

2 ted for large data sets that are distributed densely across space and time.

3 mutations account for only about half of all densely affected cutaneous melanoma families, and the ca

4 semiconducting carbon nanotubes (CNTs) into densely aligned evenly spaced arrays is required for ult

5 a macroscopic gel which transitioned from a densely and covalently crosslinked network to one with l

6 For instance, densely and sparsely grafted nanoparticles show distinct

7 , where a core and a periphery are groups of densely and sparsely interconnected nodes, respectively.

8 rneurons in the NAc are tonically active and densely arborized and thus well suited to modulate NAc f

9 We demonstrate that the spots can be densely arranged on a microfluidic device without signif

10 Six densely-arranged stalked sporocarps were engulfed in tre

11 e, some visual features are sampled far more densely at certain retinal locations than others.

12 acing of individual pyramidal neurons within densely Brainbow-labeled tissue, and multiplexed whole-b

13 Xyloglucans were also densely branched with monomeric and/or dimeric side chai

14 restricted to S5 that were smaller and more densely branching.

15 l-laden hydrogels may help sustain thick and densely cellularized engineered tissues, and assist inte

16 report a double helical conformation in the densely charged aromatic polyamide poly(2,2'-disulfonyl-

17 s exclude ribosomes and consist of a core of densely clustered 26S proteasomes surrounded by a loose

18 istinctive 3-dimensional structure exhibited densely clustered cariogenic pathogens that were surroun

19 ains unclear how these motors move along MTs densely coated with obstacles of various sizes in the cy

20 Furthermore, densely coating the outer surface of DNA brick nanostruc

21 realization that genetic information is more densely coded and that the proteome is more complex than

22 Mucosal barriers are densely colonized by pathobiont microbes such as Candida

23 The human gut microbiome is comprised of densely colonizing microorganisms including bacteriophag

24 lum-like as free-living aerobic heterotroph, densely colonizing the mesogleal axis inside the gastric

25 one, for example, the relative proportion of densely compact, homogenous (type I) bone versus more tr

26 ing correlated regions in complex systems as densely connected clusters.

27 In this work, a three-dimensional (3D) densely connected convolutional neural network (DCNet) i

28 A Densely Connected Convolutional Neural Network (or Dense

29 The LDCs are mainly non-hubs, but form a densely connected group overlapping on spatially segrega

30 rons, but in males PHC differentiates into a densely connected hub sensory neuron/interneuron, integr

31 ivity shows that the insula, one of the most densely connected hubs in the developing cortex, is a ma

32 We propose to use a densely connected mixed-scale network model to capture t

33 he connectivity among top genes; (ii) detect densely connected modules based on interactions among to

34 etween TADs in a chromosomal contact map and densely connected modules in a network, we formulate TAD

35 trade coverage for sensitivity, although the densely connected nature of biological networks suggests

36 that each network has exactly one large and densely connected subnetwork or core.

37 ch that nodes in the same community are more densely connected to each other than to the rest of the

38 The claustrum is densely connected to the cortex and participates in brai

39 aracterized by the emergence of larger, more densely connected, and more highly clustered spatial fun

40 um, longer WM tracts and areas that are more densely connected, in particular the sensorimotor networ

41 Case networks were more densely connected.

42 pture features at different image scales and densely connecting all feature maps with each other.

43 n that are dominated by organic ligands that densely cover the surface of nanocrystals.

44 As a population, LPLC2 neurons densely cover visual space and terminate onto the giant

45 Cellular membranes are densely covered by proteins.

46 Section 1 was less shaded and more densely covered with submerged macrophytes compared to s

47 The body of this species is densely covered with thin and long setae, suggesting its

48 e, because weakly interacting species can be densely covering surfaces at room temperature only when

49 While densely cross-linked and hydrolytically stable polyester

50 ation of polymer network in hydrogels, where densely cross-linked polymers serving as a framework are

51 ral adaptations of a crab inhabiting a flat, densely crowded environment, where most object motions a

52 The synthesis highlights the assembly of a densely decorated pyrrolidinone core via an aza-Payne/hy

53 revealed that repressed B compartments were densely decorated with H3K27me3 but not H3K9 or DNA meth

54 ley, Colorado, which is in the middle of the densely developed Denver-Julesburg basin.

55 metry provided site-specific compositions of densely distributed high-mannose and complex-type N-glyc

56 , we show that pulvinocortical terminals are densely distributed in the extrastriate cortex where the

57 , especially when these are contained within densely distributed super-resolution data.

58 models propose that MF inputs could be more densely encoded within the CGC layer than previous model

59 is strategy is demonstrated for constructing densely exposed Fe-N(x) moieties on hierarchically porou

60 Nav1.5 is densely expressed at the intercalated disk, and narrow i

61 alpha3* nAChRs are densely expressed by medial habenula (mHb) neurons, whic

62 it is known that opioid receptors (ORs) are densely expressed in both the brain and periphery, it is

63 PAR1 is a G-protein-coupled receptor densely expressed in the CNS, however there is limited i

64 that the diabetes-associated gene Tcf7l2 is densely expressed in the medial habenula (mHb) region of

65 ancient small brain area in the epithalamus, densely expresses nicotinic acetylcholine receptors and

66 ive in molecules where the electronic states densely fill a wide energy window (on the scale of elect

67 interior of nuclear pore complexes (NPCs) is densely filled with FG-nucleoporins that form a permeabi

68 ntional barbell-like configuration, with two densely folded B compartments separated by a central A c

69 It is also possible that such densely folded materials could present a considerable ba

70 us blacki was a giant hominid that inhabited densely forested environments of Southeast Asia during t

71 is work paves a way towards very compact and densely functional neuromorphic computing primitives, an

72 This robust method results in densely functionalised 1,2,3-triazoles that remain chall

73 ructural assignment of the unprecedented and densely functionalized (Z)-alpha-phosphino-beta-boryl ac

74 In the presence of 5 mol % FeCl(3), densely functionalized 2-piperidinones containing two ne

75 ducts and indolizines were investigated, and densely functionalized adducts were obtained in yields o

76 imple and practical method to rapidly access densely functionalized alkyl boronate esters from abunda

77 reaction followed by ring opening results in densely functionalized alpha,beta-unsaturated delta-lact

78 reactions of 2-trifluoromethyl oxirane give densely functionalized and highly versatile trifluoromet

79 The products are densely functionalized and ripe for further transformati

80 ble into nanoscale polymeric micelles with a densely functionalized aptamer-displaying corona.

81 eir structural complexity is embodied in the densely functionalized core, possessing a series of cont

82 molecule of methyl acrylate, resulting in a densely functionalized cyclohexene ring formation.

83 The reaction provides densely functionalized cyclopenta[b]indolines with versa

84 se pathogens express structurally unique and densely functionalized glycans on their surfaces which a

85 on (DLC) is experimentally demonstrated with densely functionalized graphenes displaying dynamic inte

86 o been exploited toward tunable synthesis of densely functionalized heteroarenes through challenging

87 lticomponent approach to access a library of densely functionalized homo- and hetero-multivalent glyc

88 A range of densely functionalized indolines (18 examples) is obtain

89 ons, thus allowing the rapid construction of densely functionalized molecules.

90 nted chemistry provides an easy route toward densely functionalized molecules: Amines, alcohols, and

91 r the rapid construction of a novel class of densely functionalized picolinates.

92 potential for the sustainable production of densely functionalized pyrroles from cheap and widely av

93 oxoacetonitriles, and ammonium acetate gave densely functionalized pyrroles in 75-96% yields.

94 n then yield these sterically encumbered and densely functionalized quaternary amino acids.

95 he utility of the method in the synthesis of densely functionalized small molecules suitable for frag

96 spidospermatan-type alkaloids from a linear, densely functionalized substrate.

97 However, cross-coupling of densely functionalized substrates remains a major challe

98 emistry allows for synthesis of forskolin, a densely functionalized terpenoid, in 14 steps from comme

99 al-organic framework nanoparticles (MOF NPs) densely functionalized with oligonucleotides can be prog

100 s Minireview, we describe synthetic polymers densely functionalized with sequence-defined biomolecula

101 The MOFs act as protein hosts, and their densely functionalized, oligonucleotide-rich surfaces ma

102 genome-wide meta-analysis of LTL by pooling densely genotyped and imputed association results across

103 RTANCE Coronavirus spike proteins are large, densely glycosylated macromolecular machines that mediat

104 5-kDa protein fragment, originating from the densely glycosylated mucin domain (~250 kDa).

105 iotensin-converting enzyme 2 (ACE2) are both densely glycosylated.

106 gered by mucins, which are polymers that are densely grafted with O-linked glycans that form the 3D s

107 icron-sized features of DNP are presented as densely immobilized conjugates of bovine serum albumin (

108 This projection terminates most densely in Layer III with sparser termination in Layers

109 CA1 and subicular projections terminate most densely in Layers V and VI of the entorhinal cortex, wit

110 PNOC(ARC) neurons arborize densely in the ARC and provide inhibitory synaptic input

111 pled the segregation/integration performance densely in time.

112 These neurons also densely innervate ascending targets implicated in the ce

113 of both sexes), that corticotrigeminal axons densely innervate SpVc, where they target and directly a

114 Mesenteric arteries are densely innervated and the nerves are important regulato

115 Both are densely innervated by dopaminergic fibers, and are an in

116 We hypothesized that EGCs, which are densely innervated by excitatory mitral cells (MCs), wou

117 VP is densely innervated by orexin fibers and is known to regu

118 the secondary auditory field (A2), we found densely innervated CTB-positive axon terminals that were

119 g learning, fast-spiking interneurons (FSIs) densely innervated glutamatergic projection neurons (PNs

120 n using the cornea, a normally avascular and densely innervated ocular tissue, as a model.

121 Further, many tumor types are more densely innervated than their normal tissues of origin.

122 Hypothalamic MCH neurons densely innervated the dorsal hippocampus.

123 The cornea is densely innervated to sustain the integrity of the ocula

124 The skin is densely innervated with nociceptive neurons specialized

125 ior thalamic nucleus (medial part, POm) most densely innervates L1 and L5A.

126 al (VPM) somatosensory thalamic nucleus most densely innervates layer 4 (L4) barrels, whereas the hig

127 e other individualized symptom networks were densely interconnected clusters of symptoms.

128 ontaining many areas and cell types that are densely interconnected in complex ways, and for which ge

129 Across various densely interconnected neuron clusters, G-Cut achieves s

130 world network architecture, where cliques of densely interconnected neurons ("small worlds") communic

131 tif: populations of pyramidal cells that are densely interconnected with inhibitory neurons.

132 and predicts that stress accumulates within densely intruded regions of the volcano, blocking subseq

133 In this study, we compared the effects of densely-ionizing deuterons and sparsely-ionizing X-rays

134 morphology of large neuronal populations in densely labeled brains.

135 onal single-particle tracking and imaging in densely labeled cortex.

136 localization of individual molecules even in densely labeled samples and in cellular and tissue envir

137 r, a prototypical G-protein coupled receptor densely localized in the midbrain periaqueductal gray.

138 urden of manual synapse annotation for large densely mapped connectomes.

139 rt that the LTF CpG island is frequently and densely methylated in high-grade prostatic intraepitheli

140 udy, we show that KIR proximal promoters are densely methylated in less mature CD56(bright) NK cells

141 Because KIR genes are densely methylated in NK cell progenitors, there is an i

142 unravel the biosynthesis of one of the most densely modified and metabolically obscure ribosome-deri

143 mensional superlattices, where nanoparticles densely modified with DNA can be viewed as "programmable

144 previous observations that V3d and PO/V6 are densely myelinated relative to adjacent cortex and share

145 Mucin domains are densely O-glycosylated modular protein domains that are

146 Densely O-glycosylated mucin domains are found in a broa

147 to kill competing bacterial prey species in densely occupied niches.

148 low-downs as new species pack into ever more densely occupied regions of ecological niche space.

149 results indicate that sequence space is not densely occupied.

150 orpuscles are mechanosensory end organs that densely occupy mammalian glabrous skin.

151 a its long coiled-coil domain and associates densely on the repetitive sequence of the phosphorylated

152 Densely opaque axoplasmic sentinels are arranged along n

153 en Tetrahymena chromosomes are normally most densely packaged.

154 mbrane, composed of directionally unaligned, densely packed actin filaments, most shorter than 150 nm

155 In skeletal muscle fibers, mitochondria are densely packed adjacent to myofibrils because adenosine

156 Densely packed Ag3 PO4 particles form a non-oscillating

157 In cyanobacteria, Rubisco enzymes are densely packed and encapsulated in a specialized organel

158 rons projecting to the cingulate cortex were densely packed and more evenly distributed throughout th

159 onger binding to sugar-binding proteins than densely packed arrangements of sugars.

160 show that although metals are highly opaque, densely packed arrays of metallic nanoparticles can be m

161 In recent years, metasurfaces consisting of densely packed arrays of optical antennas have been demo

162 ss of self-organization that operates within densely packed bacterial populations.

163 matrix-secreting V. cholerae variants, whose densely packed biofilm structures displace competitors f

164 detection and cellular shape measurement in densely packed biofilms are challenging because of the l

165 The migration of densely packed cells generated strong signals, while dis

166 Heterochromatin, a densely packed chromatin state that is transcriptionally

167 light-harvesting systems spatially organize densely packed chromophore aggregates using rigid protei

168 Yu et al. show programmable, densely packed clusters using thermally expandable soft

169 eract with their luminal environment using a densely packed collection of apical microvilli known as

170 nging nano- and microcapsules with shells of densely packed colloidal particles closer to application

171 lamellar bodies (LBs), organelles containing densely packed concentric membrane layers, for storage a

172 nd that compact metaphase chromosomes have a densely packed core along their cylindrical axes that ex

173 The densely packed crossbar arrays of individually accessibl

174 Densely packed Cu NP ensembles underwent structural tran

175 -assembly of bright nanomaterials containing densely packed dyes.

176 cate the significant potential of generating densely packed endothelial networks together with electr

177 ical for planar-orientated cell divisions in densely packed epithelia.

178 We observed less densely packed fibrillin-1-rich microfibrils with irregu

179 A densely packed gold nanoparticles on the rGO-MWCNT platf

180 of the corneal endothelium most affected by densely packed guttae.

181 Acipenseriform fish, densely packed in the deposit, contain ejecta spherules

182 eal that at the nanoscale, while the QDs are densely packed into the center of the co-assemblies, the

183 e-dimensional DNA nanostructures designed on densely packed lattices.

184 residue types and remains disordered in the densely packed liquid phase.

185 They consist of densely packed LixM (M = Si, Sn, or Al) nanoparticles en

186 ectance is mediated by a continuous layer of densely packed melanosomes in the exterior-most layer of

187 The densely packed microtubule (MT) array found in neuronal

188 In the presence of 0.04 mg/mL LRAP, however, densely packed mineral layers, comprising bundles of sma

189 a nanoplasmonic substrate, which consists of densely packed mushroom-like nanostructures with silicon

190 to 50 wt% silica nanoparticles) and feature densely packed nanoparticles uniformly distributed over

191 xcitons are a direct result of exceptionally densely packed pigments in photosynthetic proteins.

192 -resolution visual prostheses require small, densely packed pixels, but limited penetration depth of

193 is also consistently associated with large, densely packed seeds.

194 surface leads to a more uniform coverage of densely packed silver nanoparticles of approximately 50

195 ordered matrix, demonstrating low losses and densely packed single modes.

196 observations of high NH(4) (+) levels in the densely packed spermathecae of mated females.

197 NOB formed densely packed spherical clusters with a low surface are

198 g attribute this high specific capacity to a densely packed stage-I graphite intercalation compound,

199 -invasively is challenging due to its small, densely packed structures deep within the brain.

200 ence-based clustering, is capable of probing densely packed structures which vary in scale.

201 Layered graphene oxide membranes (GOM) with densely packed sub-nanometer-wide lamellar channels show

202 ns, as well as molecular differences between densely packed synapses.

203 Eukaryotic cells are densely packed with macromolecular complexes and intertw

204 ually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) that a

205 of cross-linked PSGs revealed that PSGs are densely packed with proteasomes and contain ubiquitin bu

206 The pyrenoid matrix is densely packed with the CO2-fixing enzyme Rubisco and is

207 This hydrophobic exterior allows gold to be densely packed within ~150 nm polymeric micelles.

208 Our strategy provides densely packed yet ultralight clusters with a variety of

209 mobility across dividing cells that contain densely packed, dynamic microtubules, comprising the met

210 lasm to equalize mesoscale mobility across a densely packed, dynamic, non-uniform environment, thus s

211 ffusing rather freely, in reality the DNA is densely packed, is not rigid but highly mobile, and the

212 designed for situations in which nuclei are densely packed, nonspherical, or heterogeneous in shape,

213 cades have the potential to deliver complex, densely packed, polycyclic architectures, with control o

214 Superresolution microscopy recently revealed densely packed, rapidly moving ER tubules mistaken for s

215 ional microshells formed by self-assembly of densely-packed 5 nm gold nanoparticles (AuNPs).

216 of two protofibrils that are connected via a densely-packed interface formed by residues 50-57 (Guerr

217 odomains', charged nucleotides interact with densely-packed membranes and biomolecules.

218 n templated method which allows formation of densely-packed quasi-spherical Au/Ag colloidal aggregate

219 ng of skin texture patterns which consist of densely-packed, reticulate arrays of small (<0.5 mm) pol

220 However, such densely phenotyped longitudinal studies are still rare a

221 nitive and clinical data were collected in a densely phenotyped pediatric cohort (N=160; 70 with ADHD

222 The FHS cohorts are densely phenotyped, with recurring follow-up examination

223 chitecture parameters of sorghum, a tall and densely planted crop species.

224 back repression of the mevalonate pathway in densely-plated glioma cells.

225 These neurons densely populate the paraventricular nucleus of the hypo

226 ug/m(3) (23.9-36.2%), were identified in the densely populated air basins of San Francisco Bay Area,

227 e-month-ahead prevalence prediction within a densely populated all-year-round malaria metropolis of o

228 rations of PAHs and PCBs were found close to densely populated and industrialized regions, i.e., in t

229 Hence, this densely populated area is more likely to act as an accel

230 ndhand smoke exposure, and residence in more densely populated areas and in areas with fewer faciliti

231 ver disease nationwide, particularly in less densely populated areas and in community-based practices

232 power lead to similar health benefits across densely populated areas of Asia and Europe, we find that

233 In densely populated areas only few very long rivers remain

234 action of emissions, concentrated in or near densely populated areas, plays an outsized role in damag

235 In densely populated areas, traffic is a significant source

236 s of temperate forests, in particular around densely populated areas.

237 in watersheds around the world including in densely populated areas.

238 persists within splenic granulomas that are densely populated by CD11b(+)CD11c(+)Ly6C(+) macrophages

239 ted by sensory and autonomic nerves, and are densely populated by resident immune cells, allowing rap

240 ons of several potentially harmful metals in densely populated cites worldwide motivates expanded mea

241 )) and ozone (0.4-0.7 ppbv) occur around the densely populated cities in East and West Africa.

242 assess the annual heat-related mortality in densely populated cities of China at 1.5 degrees C and 2

243 flooding because of their low elevations and densely populated cities.

244 These regions coincide with the most-densely populated coastal region of Chile and the most-i

245 density-dependent transmission and implicate densely populated communities as key sources of viral di

246 on child diarrhoea prevalence in low-income, densely populated communities in urban Bangladesh.

247 cially target racial and ethnic minority and densely populated communities.

248 Mucus is a densely populated ecological niche that coats all non-ke

249 (O(2)) and high carbon dioxide (CO(2)) of a densely populated fossorial nest.

250 stem (InaTEWS), especially in Java, the most densely populated island in Indonesia.

251 ly by amalgamating neighboring bacteria into densely populated microcolonies.

252 ial effects are shared across many people in densely populated neighbourhoods.

253 The densely populated North Sea region encompasses catchment

254 uary is located in Massachusetts Bay off the densely populated northeast coast of the United States;

255 socio-economic impacts over one of the most densely populated parts of the world.

256 pical Andes with deleterious effects on this densely populated region of South America.

257 the model increases rainfall by 10-70% over densely populated regions in India and 10-30% over north

258 Coastal zones, the world's most densely populated regions, are increasingly threatened b

259 f airfields are common and may affect large, densely populated residential areas.

260 of malaria vectors is grossly lacking in the densely populated Sahelo-Sudanian region of Nigeria.

261 visualization reveals structural ordering as densely populated small clusters in a nanorod heated fro

262 Singapore is one of the most densely populated small island-states in the world.

263 nized threat, an eventual HF epidemic in the densely populated South Asian nations could have dramati

264 nature of movement of B. pseudomallei within densely populated Southeast Asia.

265 d-culture surveillance studies, largely from densely populated urban centers.

266 ives significant sympathetic innervation, is densely populated with a diverse microbial ecosystem, an

267 Using neonatal C57/Bl6 mouse ovaries densely populated with primordial follicles, CCND2 prote

268 65 individuals in 2017/2018 in a high-income densely-populated area of China, Shanghai City.

269 igher in US counties that were more urban or densely-populated or that had more crowded housing, air

270 om diverse basal forebrain GABAergic neurons densely project in all layers of the olfactory bulb.

271 gnition, a behavior that is supported by the densely recurrent primate ventral stream, culminating in

272 Here we densely sample adaptive mutations in Saccharomyces cerev

273 The densely sampled alignment provides a single-base-pair ma

274 ng from West Sacramento, CA to Woodland, CA, densely sampled at 2 m spacing.

275 whom' in an infectious disease outbreak from densely sampled case data, with most recent studies focu

276 we quantified spatial trends in the rich and densely sampled fossil history of brachiopods and bivalv

277 for this study, representing one of the most densely sampled genomic-scale data sets available.

278 is on North America, which has a relatively densely sampled history.

279 Using a densely sampled HIV-infected population, we show no evid

280 ional cerebellar networks at rest in a woman densely sampled over a complete menstrual cycle (30 cons

281 me proposed in the Lepanthes clade producing densely sampled phylogenies with Maximum Parsimony, Maxi

282 ealed transmission cluster expansion in this densely sampled region and allowed estimates of Re to mo

283 these variables on the HIV phylogeny of the densely sampled Swiss HIV Cohort Study.

284 Using infant marmoset monkeys, we densely sampled vocal, postural and locomotor behaviors

285 Here we utilize a densely sampled, multi-source dataset to examine how cli

286 ctionalized hydrogels, serum-free media, and densely seeded good manufacturing practice protocol-grad

287 high spatial-frequency 3D motion fields from densely seeded single-particle layer images.

288 -selected reference panels without requiring densely sequenced data in family members, while imputati

289 progenitor D-genome reference sequence with densely spaced BES anchor points and computational filte

290 ing cascade is designed for the synthesis of densely substituted 4-alkoxy quinolines via an oxonium i

291 c strategy has been developed for assembling densely substituted arabinoxylan oligosaccharides, which

292 developed protocol enabled the formation of densely substituted chiral 2-aryl ferroceneamides, exhib

293 Densely substituted fused aromatic triazenes can be prep

294 chemical oxidation and enabled access to the densely substituted oxetane in one step.

295 ing of high aspect ratio, 2D sheets that are densely surface-decorated with DNA.

296 an neutrophils, phagocytic immune cells that densely surround aggregates but do not enter them.

297 ngular arrays of symmetric trimers packed so densely that the coupling between neighbouring unit cell

298 Densely tiled CRISPRi screening indicates that only LCR

299 ior bed nucleus of the stria terminalis, and densely to the lateral hypothalamus.

300 the proposed algorithm accurately identified densely vascularized regions from the rest of the tumor.