ライフサイエンスコーパス: dental caries

1 2 diabetes), and a prospective cohort study (dental caries).

2 tic acid, reducing the local pH, and causing dental caries.

3 rming oral pathogen commonly associated with dental caries.

4 s as well as new insights in the etiology of dental caries.

5 hogens and commensals in the pathogenesis of dental caries.

6 uced cariogenicity in vivo in a rat model of dental caries.

7 disease and metabolism of sugar alcohols in dental caries.

8 in genes lacking known or plausible roles in dental caries.

9 ociation between amount of sugars intake and dental caries.

10 dered the principal cariogenic bacterium for dental caries.

11 ptococcus mutans, a causative agent of human dental caries.

12 between hair disorders and susceptibility to dental caries.

13 1T) and KRT75(E337K), are prone to increased dental caries.

14 proved nor precluded their associations with dental caries.

15 t children in a trajectory of high levels of dental caries.

16 -kingdom interaction for the pathogenesis of dental caries.

17 treptococcus mutans is prominently linked to dental caries.

18 nd its essential role in the pathogenesis of dental caries.

19 ssociation between PAD and periodontitis and dental caries.

20 ng to active and passive vaccination against dental caries.

21 ry teeth that are particularly vulnerable to dental caries.

22 e biofilm and the primary causative agent of dental caries.

23 is a widely recognized etiological agent of dental caries.

24 ey organisms associated with the etiology of dental caries.

25 uller understanding of the genetic risks for dental caries.

26 There are many determinants of children's dental caries.

27 er of the oral plaque and is associated with dental caries.

28 roduction reduces the local pH, resulting in dental caries.

29 expression and activation were increased in dental caries.

30 een a focus for immunization studies against dental caries.

31 rimary etiological agent in the formation of dental caries.

32 he pathogenesis of S. mutans associated with dental caries.

33 iding further insight into the prevention of dental caries.

34 juice was less likely to be associated with dental caries.

35 le that diet and sealants have in preventing dental caries.

36 is an effective agent for the prevention of dental caries.

37 g the study period, 28,623 (23.7%) women had dental caries.

38 S. mutans plays a key role in dental caries.

39 h mutans streptococci and the development of dental caries.

40 view of potential new diagnostic methods for dental caries.

41 rapy was not identified as a risk factor for dental caries.

42 ent of new technologies for the detection of dental caries.

43 tans, the primary etiological agent of human dental caries.

44 erval, 1.07, 1.23) compared to those without dental caries.

45 ivity to fluoride for a better prevention of dental caries.

46 valence and severity of dental fluorosis and dental caries.

47 sociation between breastfeeding duration and dental caries.

48 wide range of infectious diseases, including dental caries.

49 useful strategy to combat the prevalence of dental caries.

50 and conditionally-independent risk loci for dental caries.

51 en associated with a decreased prevalence of dental caries.

52 res some risk factors with periodontitis and dental caries.

53 is a major contributor to the development of dental caries.

54 , hypertension, obesity-related cancers, and dental caries.

55 ponses to the levy on obesity, diabetes, and dental caries.

56 gent for dentin-pulp complex regeneration in dental caries.

57 the relationship between SDS and/or RDS and dental caries; 16 (12 studies) considered oral cancer; a

58 ting against demineralization of teeth (i.e. dental caries), a highly prevalent infectious disease as

59 is considered the primary etiologic agent of dental caries, a global health problem that affects 60 t

60 ococcus mutans is a major etiologic agent of dental caries, a prevalent worldwide infectious disease

61 especially in liquid form, increases risk of dental caries, adiposity, and type 2 diabetes.

62 Dental caries affects most adults worldwide; however, th

63 cies associated with periodontal disease and dental caries after a 2-week program.

64 g them, 4,741 (16.6%) women were treated for dental caries after diagnosis.

65 Experiments then compared experimental dental caries after immunization with SYI-CAT, SYI, or C

66 uccessfully uncover the precise locations of dental caries, allowing convenient screening of hidden d

67 h Sjogren's syndrome have elevated levels of dental caries, along with the loss of many teeth, early

68 Dental caries, although preventable, remains one of the

69 we examined variability in susceptibility to dental caries among children and adolescents in rural Ap

70 is warranted to determine if disparities in dental caries among women are due to differences in pari

71 was an association between HIV infection and dental caries among women enrolled in the Women's Intera

72 omising strategy for reducing disparities in dental caries among young children.

73 tudy was to evaluate the association between dental caries and adverse pregnancy outcomes and the eff

74 Dental caries and dental visiting patterns have been rec

75 t lip and palate have a higher prevalence of dental caries and gingivitis.

76 (SDF) is used topically to prevent or arrest dental caries and has been tested clinically in toddlers

77 ost inputs: diet and behavior in the case of dental caries and immune system interactions in the case

78 Dental caries and its treatment were not associated with

79 parts, Indigenous persons had more untreated dental caries and missing teeth, fewer teeth that had be

80 tion between the amount of sugars intake and dental caries and on the effect of restricting sugars in

81 ptococcus mutans is the etiological agent of dental caries and one of the many bacterial species impl

82 Better understanding of dental caries and other oral conditions has guided new s

83 in public health that oral diseases such as dental caries and periodontal disease and general health

84 Both dental caries and periodontal disease are mediated by sy

85 Dental caries and periodontal disease are together the m

86 acy of hygiene-therapists when screening for dental caries and periodontal disease in regularly atten

87 giene-therapists could be used to screen for dental caries and periodontal disease.

88 oth sets of clinicians made an assessment of dental caries and periodontal disease.

89 e the sensitivity and specificity values for dental caries and periodontal disease.

90 cines to combat other oral diseases, such as dental caries and periodontal diseases.

91 Dental caries and periodontitis account for a vast burde

92 and early diagnosis of oral diseases such as dental caries and periodontitis, can be potentially achi

93 oral microbes contribute to the formation of dental caries and periodontitis; however, there is littl

94 s essential to develop strategies to prevent dental caries and plaque formation.

95 s and confounders assessed were governorate, dental caries and restorations, and obesity by waist cir

96 nts with hyposalivation are at high risk for dental caries and thus require aggressive oral hygiene r

97 y, there was no increased risk in women with dental caries and treatment compared with those without.

98 io on prevalence of obesity and incidence of dental caries and type 2 diabetes.

99 entification of the bacteria associated with dental caries and with dental health in a subset of 204

100 ns is the primary etiological agent of human dental caries and, at times, of infective endocarditis.

101 s) were included: 22 assessed the effects on dental caries, and 1 considered oral cancer.

102 ive association between periodontal disease, dental caries, and cocaine use, select co-usage elevated

103 ssers showed less periodontal disease, fewer dental caries, and loss of fewer teeth over a 5-y period

104 health-related quality of life, outcomes of dental caries, and outcomes of tooth loss.

105 streptococci are major etiological agents of dental caries, and several of their secreted products co

106 es into resin for Ca-PO(4) release to combat dental caries, and to investigate the filler level effec

107 h concerns, including nutrient displacement, dental caries, and weight gain.

108 countries, universal health problems such as dental caries, anemia, ophthalmologic conditions, and hy

109 rious characteristics of mothers who develop dental caries are not treated.

110 tified include the misconception of defining dental caries as a tooth or surface-level condition vers

111 old increase in presentation and severity of dental caries as compared with wild-type control mice.

112 on with log link function on 3-time repeated dental caries assessments.

113 ether sugar-related feeding practices affect dental caries between the ages of 6 and 18 y.

114 he expected detrimental effect of sucrose on dental caries but no effect on CHD.

115 f the treatment of dental caries, women with dental caries but no treatment had an increased risk of

116 tis, and, for some NAFLD measures, untreated dental caries but not overall caries experience after co

117 igated the differential effects of MA use on dental caries by comparing the patterns of decayed, miss

118 3F1 treatment effectively prevented dental caries by controlling S. mutans in a rat caries m

119 Dental caries can be described as a dysbiosis of the ora

120 Dental caries can compromise quality of life and is asso

121 of moderate-severe periodontitis, untreated dental caries, caries experience, and tooth loss (<20 te

122 t demonstrates activity against the dominant dental caries-causing pathogen as well as the first lysi

123 mutans, the primary causative agent of human dental caries, contains a single copy of the gene encodi

124 Dental caries continues to be a common chronic disease o

125 Dental caries covers the continuum from the first atomic

126 intraclass correlation coefficient (ICC) for dental caries data at tooth and surface level, 2) to pro

127 The ICC for dental caries data was 0.21 (95% confidence interval [CI

128 In the United States, dental caries (decay) is the most common chronic childho

129 ammatory mediators, including pericoronitis, dental caries, dentate status, root remnants, and gingiv

130 ow level of sugar consumption was related to dental caries, despite the use of fluoride.

131 lts worldwide; however, the risk factors for dental caries do not necessarily exert their effects uni

132 aries (DFS), parity was related to untreated dental caries (DS).

133 nstrated that TA@RAs could prevent secondary dental caries effectively.

134 rimary etiological agent in the formation of dental caries, encodes at least 18 TetR regulators.

135 Dental caries, endodontic infections and periodontal dis

136 and LPO) with plausible biological roles in dental caries exhibited suggestive evidence for associat

137 endance behaviors; those would lead to lower dental caries experience and better self-reported oral h

138 idate genes for evidence of association with dental caries experience in 13 race- and age-stratified

139 ionship between oral arginine metabolism and dental caries experience in children, we measured ADS ac

140 attern; they also had a significantly higher dental caries experience in the primary dentition than d

141 were used to generate two common indices of dental caries experience which were tested for associati

142 ding, dental fracture, dental fluorosis, and dental caries experience.

143 randomized or controlled clinical trials on dental caries, fluorides, sealants, and "restorative" ca

144 The first genome-wide association study of dental caries focused on primary teeth in children aged

145 dietary carbohydrates caused an increase in dental caries following the development of agriculture,

146 Lactobacilli have been associated with dental caries for over a century.

147 utans, a major oral pathogen responsible for dental caries formation, possesses a variety of mechanis

148 Dental caries forms through a complex interaction over t

149 tudinal studies to report the development of dental caries from childhood into adolescence.

150 ugar-related feeding practices on changes in dental caries from early childhood to young adulthood.

151 dustry could not deny the role of sucrose in dental caries given the scientific evidence.

152 idated through the analysis of a large-scale dental caries GWAS data set.

153 In a multivariable analysis, women with dental caries had an increased risk of delivering large-

154 ance of susceptibility genes in the risk for dental caries has been clearly established.

155 th loss, the relationship between parity and dental caries has not been extensively investigated.

156 extraoral infections, but its relevance for dental caries has only been theorized to date.

157 iated with the initiation and progression of dental caries has yet to be fully characterized.

158 tans, the primary etiological agent of human dental caries, has developed multiple mechanisms to colo

159 Streptococcus mutans, a primary agent of dental caries, has three (p)ppGpp synthases: RelA, which

160 ed genome-wide association scans (GWASs) for dental caries in a population-based cohort of 12 000 His

161 found fluoride to be effective in preventing dental caries in adults.

162 ol vs. placebo lozenges in the prevention of dental caries in caries-active adults.

163 idemiological study of oral microbiology and dental caries in children from a localized Alabama popul

164 studies demonstrated a greater prevalence of dental caries in children residing in radiation-contamin

165 ealth (DR-BNI)-in reducing the recurrence of dental caries in children who have a primary tooth extra

166 imerosal and of dental amalgam for repair of dental caries in children.

167 ificantly reducing the risk of recurrence of dental caries in children.

168 cal effectiveness of FS and FV in preventing dental caries in first permanent molars (FPMs) in 6- to

169 The increased risk of dental caries in HI children suggest immune-mediated cha

170 efficient carbohydrate for the promotion of dental caries in humans, and the primary caries pathogen

171 The causative agent of dental caries in humans, Streptococcus mutans, outcompet

172 reptococcus mutans is a primary pathogen for dental caries in humans.

173 primary causative agent in the formation of dental caries in humans.

174 lear is how the distribution and severity of dental caries in MA users differ from the general popula

175 Dental caries in pre-school children has significant pub

176 3 treatment strategies over 3 y for managing dental caries in primary teeth in UK primary dental care

177 The high prevalence of dental caries in recent humans is attributed to more fre

178 h biofilm microbiota composition and risk of dental caries in Swedish adolescents.

179 ks by young children is a risk indicator for dental caries in the primary dentition and should be dis

180 ofilms by 3F1 was able to effectively reduce dental caries in vivo without affecting the overall oral

181 xylitol-containing tooth-wipes in preventing dental caries in young children.

182 Adjusted analysis showed that dental caries increment ratio between ages 6 and 18 y wa

183 mption along the life course, the higher the dental caries increment.

184 Reports that compare dental caries indices in HIV-seropositive (HIV+) subject

185 Dental caries induced by Streptococcus mutans is one of

186 tive GTF and demonstrated protection against dental caries infection after immunization, implying tha

187 Dental caries is a cariogenic bacteria-mediated, ferment

188 Dental caries is a chronic infectious disease of multifa

189 Dental caries is a costly and prevalent disease characte

190 Dental caries is a microbially mediated disease that can

191 Dental caries is a prime example of a biofilm-dependent

192 Dental caries is a ubiquitous disease affecting all age

193 Dental caries is an infectious disease that causes tooth

194 l, behavioral, and community determinants of dental caries is based on cross-sectional analyses.

195 Dental caries is closely associated with the virulence o

196 Dental caries is considered a diet-mediated disease, as

197 The eventual outcome of dental caries is determined by the dynamic balance betwe

198 We show that the heritability of dental caries is enriched for conserved genomic regions

199 As the most common chronic disease globally, dental caries is induced by host-microbial dysbiosis in

200 Dental caries is influenced by a complex interplay of ge

201 Remineralization of dentin during dental caries is of considerable clinical interest.

202 Dental caries is one of the most prevalent infectious di

203 Previous studies report that dental caries is partially heritable, but there is uncer

204 Dental caries is prevalent, and secondary caries causes

205 Dental caries is the most common chronic disease in chil

206 Dental caries is the most common chronic disease worldwi

207 Dental caries is the most common human infectious diseas

208 lth Organization (WHO) stated that globally, dental caries is the most important oral condition.

209 Dental caries is the most prevalent infection globally a

210 occus mutans, a principal causative agent of dental caries, is considered to be the most cariogenic a

211 se, an inflammatory disease mainly caused by dental caries, is one of the most prevalent infectious d

212 ans, the primary aetiological agent of human dental caries, is unknown.

213 ontributes to the enamel-destructive disease dental caries, lacks the capabilities to generate WTA.

214 Dental caries left untreated threaten exposure of the de

215 model that specified that parity influences dental caries levels through dental care, psycho- social

216 s mutans, a major etiological agent of human dental caries, lives primarily on the tooth surface in b

217 estorative materials as useful strategies to dental caries management.

218 uggesting that the processes contributing to dental caries may have undesirable downstream effects on

219 Dental caries may lead to endodontic disease, where the

220 s reported the absolute amount of sugars and dental caries, measured as prevalence, incidence, or sev

221 The high rates and distinctive patterns of dental caries observed could be used 1) to alert dentist

222 itively associated with the control outcome, dental caries (odds ratio [OR] 1.04 per log(10) transfor

223 ed a significant genetic association between dental caries of the anterior mandibular teeth and LYZL2

224 ncy outcomes and the effect of treatment for dental caries on adverse pregnancy outcomes.

225 determine the impact of enamel fluorosis and dental caries on oral health-related quality of life (OH

226 However the influence of dental caries on pregnancy is unknown.

227 ms are associated with oral diseases such as dental caries or periodontitis.

228 Dental caries, otherwise known as tooth decay, is one of

229 ften cited as the main bacterial pathogen in dental caries, particularly in early-childhood caries (E

230 fect homeostasis and stress tolerance in the dental caries pathogen S. mutans.

231 nduced protein-encoding mRNA (irvA) from the dental caries pathogen Streptococcus mutans directly mod

232 Streptococcus mutans, a dental caries pathogen, also causes endocarditis and is

233 Two dental caries pathogenesis experiments were performed wh

234 osyltransferase (GTF), an enzyme involved in dental caries pathogenesis, was used as a test antigen.

235 us local and systemic human diseases such as dental caries, periodontal disease, obesity, and cardiov

236 and data on oral health outcomes relating to dental caries, periodontal disease, or oral cancer.

237 raphic characteristics, smoking, tooth loss, dental caries, periodontal status, and OHRQoL in adults

238 ypertensive medication; smoking; tooth loss; dental caries; periodontal status (bleeding on probing,

239 Hyposalivation contributes to dental caries, periodontitis, and microbial infections.

240 e-wide association studies (GWAS) of 5 novel dental caries phenotypes (developed by clustering the pe

241 tans, the primary etiological agent of human dental caries, possesses at least two fructose phosphotr

242 1; 95% confidence interval [CI], 1.59-3.65), dental caries prevalence (prevalence ratio, 1.29; 95% CI

243 High and upward sugar consumers had higher dental caries prevalence and mean DMFT in all cohort wav

244 For dental caries prevention, however, Chilton and Fertig an

245 ws produce conflicting conclusions regarding dental caries-preventive effects of water fluoridation i

246 cus mutans, the principal causative agent of dental caries, produces four glucan-binding proteins (Gb

247 t with a significant genetic contribution to dental caries progression and severity in both emerging

248 role of genetic and environmental factors on dental caries progression in young children was determin

249 The etiology of dental caries reflects a complex interplay of biochemica

250 n before their third birthday and subsequent dental caries-related treatment (CRT) and CRT payment.

251 able, the specific genes influencing risk of dental caries remain largely unknown.

252 DF application to teeth to prevent or arrest dental caries results in plasma and tissue silver concen

253 a potential source for accurate and reliable dental caries risk and onset.

254 S2R38, TAS1R2, GNAT3) may be associated with dental caries risk and/or protection.

255 While genetics clearly influences dental caries risk, few caries genes have been discovere

256 occus mutans, a principal causative agent of dental caries, secretes antimicrobial peptides known as

257 Dental caries (similar to periodontitis) was considered

258 a, Actinobacillus actinomycetemcomitans) and dental caries (Streptococcus mutans and S. sobrinus).

259 However, the appearance of dental caries suggest a diet high in fermentable-carbohy

260 This study reinforces the complexity of dental caries, suggesting that numerous loci, mostly hav

261 Understanding the factors influencing dental caries susceptibility may lead to improvements in

262 identify genetic factors that contribute to dental caries susceptibility, either alone or in combina

263 However, why sucrose causes severer dental caries than other sugars is largely unknown.

264 ldhood caries (ECC) is a preventable form of dental caries that affects very young children, particul

265 coccus mutans is an etiologic agent of human dental caries that forms dental plaque biofilms containi

266 During the treatment of dental caries that has not penetrated the tooth pulp, ma

267 fracture toughness that protects teeth from dental caries, the most common chronic disease worldwide

268 Dental caries, the most common chronic infectious diseas

269 Streptococcus mutans, the causative agent of dental caries, the most prevalent childhood disease.

270 dental erosion and the relationship between dental caries to GER and dental erosion.

271 ile others are linked to oral diseases, from dental caries to gum disease.

272 d the first genome-wide association scan for dental caries to identify associated genetic loci and no

273 In conclusion, this was the largest GWAS of dental caries, to date and was the first to target Hispa

274 Dental caries (tooth decay) is a polymicrobial biofilm d

275 ions for widespread application to eradicate dental caries (tooth decay) within a decade.

276 and consequential oral diseases globally are dental caries (tooth decay), periodontal disease, tooth

277 s and traits, including periodontal disease, dental caries, tooth agenesis, cancers of the head and n

278 Dental caries, tooth loss, and periodontal attachment lo

279 rpose was to evaluate the natural history of dental caries using a standardized, visually based syste

280 t this peptide may be important in a subunit dental caries vaccine.

281 n demonstrated to be effective components of dental caries vaccines.

282 ering, including the treatment/prevention of dental caries, via bioactive surface groups.

283 Dental caries was a positive control outcome.

284 plus 16-immunized groups, and the extent of dental caries was also significantly reduced in these gr

285 Childhood dental caries was clinically determined (including nonca

286 Untreated dental caries was not associated with preterm birth or p

287 l sugar consumption groups, the increment of dental caries was slightly higher between ages 6 and 12

288 tans, the primary etiological agent of human dental caries, was completed.

289 ptococcus mutans, a causative agent of human dental caries, was detected for the aqueous leaf extract

290 ns, one of the principal causative agents of dental caries, was dramatically impaired by growth of th

291 development of broader-spectrum vaccines for dental caries, we explored the immune potential of const

292 When women with dental caries were divided on the basis of the treatment

293 Dental caries were lower in each peptide-immunized group

294 th the development of periodontal disease or dental caries were overabundant in the group that did fl

295 rvations regarding a hereditary component of dental caries were reported as early as the 1920s.

296 ide varnish (FV) are effective in preventing dental caries when compared with a no-treatment control.

297 nd in biofilms of children exhibiting severe dental caries, with different degrees of lesion severity

298 ere divided on the basis of the treatment of dental caries, women with dental caries but no treatment

299 Streptococcus mutans is the leading cause of dental caries worldwide.

300 Tooth loss, dental caries, worse periodontal status, and smoking wer