ライフサイエンスコーパス: deplete

1 -length APC, but not if APC was truncated or depleted.

2 cAMP and glutathione were depleted.

3 Salmonella-infected, CD4-depleted 129X1/SvJ mice remained chronically colonized f

4 We demonstrate the use of these reagents to deplete a set of 103 proteins individually in the Drosop

5 Using small interfering RNA to deplete a subset of phosphorylated proteins not previous

6 As such, while all treatments depleted a significant proportion of Tregs, the side eff

7 on structure, we found that loss of miR-146a depleted a subpopulation of primitive, quiescent HSCs.

8 ly broad antiviral mechanism by 25HC through depleting accessible cholesterol on the plasma membrane

9 In follow-up studies, we depleted "accessible cholesterol" from the plasma membra

10 mmon lymphoid progenitors causing a severely depleted acquired immune system.

11 transcription assay in cultured cells and by depleting actin-rich processes in the tumor epithelium,

12 As a potent greenhouse gas and an ozone-depleting agent, nitrous oxide (N(2)O) plays a critical

13 th immunosuppressants (in particular, B cell-depleting agents) for attack prevention has greatly impr

14 th groups received induction with lymphocyte-depleting agents.

15 al contents in antibiotic-induced microbiota-depleted (AIMD) and control mice showed significant vari

16 tive catalytic fractionation of corn stover, depleting alkylguaiacols and alkylphenols.

17 s are unlikely to have been strong enough to deplete allelic richness by more than around 15%.

18 onsistent down-regulation across three NR2F2-depleted ALT+ cell lines.

19 cination can induce potent immune responses, deplete AML cells and prevent disease relapse.

20 standard-of-care cytoreductive chemotherapy depletes AML cells to induce remission, but is infrequen

21 By depleting an exosome core component, or components of ex

22 iNKT cells in TB-IRIS were CD4+CD8- subset depleted and degranulated around the time of TB-IRIS ons

23 nct immunologic profile in the lungs, with a depleted and exhausted CD4 and CD8 T-cell population tha

24 lly, studies in antibiotic-induced microbial depleted and in germ-free mice with and without fecal mi

25 and variance of resource availability, where depleted and more stochastic environments promote invest

26 nistration, Sertoli cells are preferentially depleted, and can be replaced to promote spermatogenesis

27 ry, tissue-resident alveolar macrophages are depleted, and monocytes from the bone marrow (BM) traffi

28 transgenic zebrafish strain, podocytes were depleted, and the glomerular response was investigated b

29 ty due to an absence of functional sperm, as depleted animals produce arrested primary spermatocytes

30 ntly attenuated by treatment of anti-CD4/CD8-depleting antibodies or anti-IFNAR1 antibody and in immu

31 d by the highly impactful effect of a B cell-depleting antibody on controlling MS.

32 ve stress markers but also rescues levels of depleted antioxidants.

33 H oxidation following ETC inhibition neither depletes asparagine nor activates the ISR, reflecting an

34 on electron transport chain (ETC) inhibition depletes asparagine, activating the ISR via the eIF2alph

35 atase knock-out (GFAP-ARO-KO) mouse model to deplete astrocyte-derived E2 in the brain and determine

36 ne, which is either permanently abrogated or depleted at a rate defined by the half-life of the prote

37 Strombine levels peaked as oxygen became depleted at dusk, indicating increased fermentation rate

38 ing R-loops accumulate during G(2)/M and are depleted at G(0)/G(1) phases of the cell cycle, and that

39 Energy stress depletes ATP and induces cell death.

40 action also drives SAM formation and further depletes ATP reserves.

41 Post-IVIG PANDAS sera and IgG-depleted baseline sera did not alter the activity of str

42 e and its subsequent reduction to l-cysteine depleted both NADPH and GSH pools, thereby allowing toxi

43 BRD9 is overexpressed in ovarian cancer and depleting BRD9 sensitizes cancer cells to olaparib and c

44 mice received an equivalent dose of nitrate-depleted BRJ (BRJ-) or normal drinking water.

45 J were compared with both 'placebo' (nitrate-depleted) BRJ as well as water to control for potential

46 ilizer, agricultural soils worldwide will be depleted by between 4-19 kg ha(-1) yr(-1), with average

47 r expression should decline as AT2 cells are depleted by hyperoxia.

48 n from a mantle source that is geochemically depleted by melt extraction rather than primitive.

49 MAIT cells were depleted by the onset of the adaptive immune response, w

50 ince they are inevitably contaminated with H-depleted byproducts.

51 A method to prepare iron-depleted CAMHB (ID-CAMHB) has been described by the Clin

52 piration during stand development-leading to depleted carbohydrate reserves and an unrealistically hi

53 An extremely isotopically depleted carbon source, such as marine methane clathrate

54 CART cells could be used as an "antidote" to deplete CART19 cells to reduce long-term side effects, s

55 al data and decreased with applied load; GAG depleted cartilage exhibited higher hydraulic permeabili

56 adjusted Mueller-Hinton broth (BMD) and iron-depleted cation-adjusted Mueller-Hinton broth (ID-BMD),

57 Depleting CD4 T cells led to increased myeloid cells in

58 was mediated by CD8 T cells because when we depleted CD8 T cells in B cell-deficient mice, these mic

59 ects of autophagy inhibition are reversed by depleting CD8(+) T cells or reducing surface expression

60 the APCs, and underwent trans-endocytosis to deplete CD80.

61 While depleting CDK4 and 6 was sufficient to limit proliferati

62 producibility and provided both enriched and depleted cell populations in a single sort.

63 Conversely, p85beta-depleted cells are less sensitive to these inhibitors.

64 Impaired RhoU activity in FASN depleted cells leads to reduced adhesion turnover downst

65 tion of key cell cycle regulators in lincNMR-depleted cells like the key dNTP synthesizing enzymes RR

66 Moreover, in TPR-depleted cells reporter mRNAs generated from short trans

67 Our measurements with the ATP-depleted cells reveal that the diffusion dynamics of the

68 The ORC5-depleted cells show normal chromatin binding of MCM2-7 a

69 ndent nuclear functions and sensitized NBAT1-depleted cells to genotoxic drugs.

70 metabolism, we studied the response of ATAD5-depleted cells to several genotoxic agents.

71 egative breast cancer cells and that CBFbeta-depleted cells undergo a mesenchymal to epithelial trans

72 of VSVG endoglycosidase H resistance in Rab6 depleted cells was delayed.

73 nd electron microscopy analysis of ESCRT-III-depleted cells with a mathematical model, we show that u

74 uced apoptosis in Nutlin-3A-treated, FLIP(L)-depleted cells, albeit to a lesser extent than in caspas

75 Consistently, in MsrB2-depleted cells, F-actin levels are decreased in ICBs, an

76 es remain energetically favorable in cohesin-depleted cells, potentially as a result of the phase sep

77 oduction of infectious particles in HSD17B12 depleted cells, supporting a specific role of VLCFA in H

78 of the tsO45 mutant of VSVG protein in Rab6 depleted cells, we found that anterograde transport at 3

79 m the nucleus and cytosol of control and TPR-depleted cells, we provide evidence that TPR is required

80 n1, an actin-depolymerizing protein, in ATG7-depleted cells.

81 pressing developing hypothalamic neurons, by depleting ciliogenic genes IFT88 and KIF3A, leads to adu

82 elicit any acute adverse reactions, bind, or deplete circulating reticulocytes or reduce BBB-expresse

83 luripotent and differentiated cells, and pre-depleting cohesin in donor cells facilitates minor ZGA a

84 ts undergoing complex medical treatments can deplete commensal bacterial strains from the intestinal

85 These therapies deplete components of the immune system with the aim of

86 Nutrient depleted compost retained its structure, but plants grow

87 Under Na(+)-deplete conditions GAD65-ChR2-EYFP mice displayed a robu

88 r fermentation to remain active under oxygen-depleted conditions.

89 experiments under ATP, DIP-replete, and DIP-depleted conditions.

90 EB) downstream of TLR4 compared to their GIV-depleted counterparts.

91 or genetic inhibition of MYC activity in SMS-depleted CRC cells dramatically induces Bim expression a

92 naive cells to migrate, which was blocked by depleting CXCL1 and IL-8 from the conditioned medium.

93 administration of cyst(e)inase, a drug that depletes cysteine and cystine, demonstrating a translata

94 Gnotobiotic colonization of microbiome-depleted dams with a limited consortium of bacteria prev

95 772 cal BP (2sigma error) which matches more depleted delta(18)O values in alpine speleothems.

96 gated either by stabilizing osmolytes, which deplete diffuse mHtt or by urea, which negates protein-p

97 P and TEAD, or genetic deletion of YAP1, all deplete dormant cells by enhancing EGFR/MEK inhibition-i

98 ification of conformational changes in Zelda-depleted Drosophila embryos; (3) patient-specific aberra

99 concentration, which changes as monomers are depleted during growth.

100 ological treatment that thins F-actin bands, depletes E-cadherin, and stimulates proliferation in lon

101 increase endothelial permeability in MYLK-L-depleted EC and Mylk-L(-/-) lungs, thus demonstrating th

102 As-received AN-102, Cs-depleted effluent, and sRF eluate fractions were compreh

103 Depleting ELP proteins promoted apoptotic cell death in

104 d Frizzled (Fzd) levels were reduced in emc1-depleted embryos, while NCC defects could be rescued wit

105 Krest)) would be increased, compensating for depleted energy stores (phosphocreatine/ATP), but potent

106 as an internal peptide surrogate in peptide-depleted environments stabilizing empty MHC I and impedi

107 entelimab) is an anti-Siglec-8 antibody that depletes eosinophils and inhibits mast cells and that ha

108 and alters the airway cellular landscape by depleting epithelial progenitors.

109 substrates from BiP observed in the calcium-depleted ER and suggest a mechanism for tuning ER qualit

110 a Ewsr1 conditional knockout mouse model to deplete EWSR1 before the onset of meiosis and found that

111 these target genes were upregulated in Rspo2-depleted explants.

112 n in excitatory neurons and radial glias but depleted expression in inhibitory neurons.

113 es R loops and genome instability induced by depleting five different unrelated factors.

114 Cells depleted for BGL3 displayed genomic instability and were

115 ce and phenotype of 2570 elderly Australians depleted for cancer, cardiovascular disease, and dementi

116 Finally, we demonstrate that NDAs are depleted for regulatory activity compared to RAs, while

117 and DNA double-strand breaks (DSBs) in cells depleted for Topoisomerase I (Top1), an enzyme that rela

118 cumulated in the trans-Golgi network and was depleted from peripheral compartments.

119 lin receptor, calcitonin receptor (CTR), was depleted from POMC neurons using an inducible mouse mode

120 have low derived allele frequency, and were depleted from promoters of essential genes, which is con

121 fectiveness when higher-risk individuals are depleted from the at-risk population at different rates

122 When mitochondrial DNA is depleted from the cells, we observed severe impairment o

123 ated with HIV-1 acquisition, and are rapidly depleted from the periphery and gastrointestinal mucosa

124 Ergosterol is depleted from this periprotein lipidome, whereas phospha

125 se lubricant into surfaces and how lubricant depletes from the surface.

126 vely affects identification of significantly depleted genes, optimal screen design can nevertheless e

127 show a marked increase in HF water use, and depleting groundwater in some semiarid regions (e.g., by

128 ate, a metabolite produced by the vancomycin-depleted gut bacteria, abrogated the vancomycin effect.

129 ditional triple-H1-knockout mouse strain and depleted H1 in haematopoietic cells.

130 In contrast, reinstating cGAS in cGAS-depleted HD cells activates cGAS activity and promotes i

131 ction of glucagon, which is known to rapidly deplete hepatic glycogen.

132 Senescent beta-catenin-depleted hepatocytes in aged mice create an inflammatory

133 nighttime uptake of Hg by vegetation, which depletes Hg from the atmosphere.

134 hole blood, one of which is also designed to deplete hgbRNAs.

135 ty and reproducibility, while simultaneously depleting highly abundant proteins such as human serum a

136 ed, as conditioning regimens are believed to deplete host T cells.

137 OCRL-depleted human cells proliferated more slowly and about

138 Furthermore, Fbw7-depleted human mesenchymal stem cells and primary mouse

139 )-induced EC migration was diminished in YY1-depleted human umbilical vein endothelial cells (HUVECs)

140 CD8 T cells, which has been observed in CD4-depleted humans.

141 The organic matter is depleted in (15)N relative to the terrestrial value at a

142 When the meningeal lymphatics are depleted in a mouse model of SAH, the degree of erythroc

143 Parasites conditionally depleted in AC9 or AC10 replicate normally but are defec

144 ntially required for the expression of genes depleted in active chromatin marks, a chromatin signatur

145 In contrast, edited COIII mRNAs are depleted in BSF by inhibition of editing progression.

146 with indirect allospecificity, B cells were depleted in C57BL/6 mice, using an anti-CD20 antibody, p

147 s in Arabidopsis, all TE-derived siRNAs were depleted in Capsella nrpd1 microspores.

148 and suggests that the mantle has become more depleted in carbon over geologic time.

149 Lunar mare basalts are depleted in F and Cl by approximately an order of magnit

150 da Galaxy (M31), RBC EXT8, that is extremely depleted in heavy elements.

151 These earthquakes are depleted in high-frequency content and typically occur n

152 Fungal diversity was depleted in host-associated communities compared with th

153 to proteins with a cationic carboxy terminus depleted in hydrophobic residues.

154 RAMOS cells in terms of the number of guides depleted in library screening and the extent of the indu

155 It is also strongly depleted in magnesium.

156 ntified whose binding sites were enriched or depleted in mutations.

157 prepared model quartz particles enriched or depleted in NFS, we demonstrate that NFS drive toxicity,

158 found that innate lymphoid cells (ILCs) were depleted in the blood and gut of people with HIV-1, even

159 her microglial cluster 7, enriched for genes depleted in the cortex of individuals with Alzheimer's d

160 When Notch or zfh1 are depleted in the mesenchymal cells, tumor growth is compr

161 Myeloid cells in the fetus were not depleted in this experiment, likely because of an inabil

162 , causing increased basal insulin secretion, depleting insulin vesicles from the cytoplasm, and impai

163 T-cells infiltrate the islets of Langerhans, depleting insulin-secreting beta-cells (insulitis).

164 otic-treated conventionally housed mice with depleted intestinal microbiomes that greater CHIKV infec

165 Lastly, we found that depleting KIF11 resulted in an increase in cilium length

166 Here we show that depleting Lama5 in LNSCs resulted in decreased Lama5 pro

167 We named this new migration mode ligand-depleting (LD) migration.

168 eroxidase (MPO) and nitric oxide (NO), while depleting levels of endogenous antioxidants such as cata

169 removal of globin gene counts in non-hgbRNA depleted libraries provides improvement in overall perfo

170 Parasites in which ERK7 has been depleted lose their conoids late during maturation and a

171 treated with IgG or anti-F4/80 antibodies to deplete macrophages during preneoplastic growth.

172 macrophages mimics the phenotype of METTL14-depleted macrophages.

173 We show in mice that B/B therapy selectively depleted mature PC producing donor-specific antibodies (

174 In the presence of Wnt5A-depleted MDSC, tumor-infiltrating lymphocytes expressed

175 obin allowed Spn to resume growth in an iron-deplete medium.

176 s the first study to show a unique, nutrient-deplete metabolic subphenotype in women with RCC, with i

177 studies, these data suggest that in dopamine-depleted mice abnormally correlated and temporally offse

178 nm diameter) were fabricated from hemoglobin-depleted mice erythrocyte-ghosts and doped with Indocyan

179 d functional decline in wild type and Clec9a-depleted mice lacking DC cross-priming function.

180 Na(+)-depleted mice showed robust preferences to "light taste"

181 and activation, we report that, in dopamine-depleted mice, (1) D2 dopamine receptor expressing stria

182 We found that, in dopamine-depleted mice, (1) the firing rate of D2-SPNs was elevat

183 ILC2 responses from control but not basophil-depleted mice, and basophils were sufficient to directly

184 olon, similar to that observed in microbiota-depleted mice.

185 ing factor 1 receptor inhibitor (PLX5622) to deplete microglia and a chronic intermittent ethanol vap

186 Furthermore, multiple strategies to deplete microglia resulted in oligodendrocytes maintaini

187 By transiently depleting microglia from the healthy adult mouse brain,

188 Depleting microglia in vivo dramatically suppressed the

189 y involved in the motor deficits of dopamine-depleted mouse models of Parkinson's disease, where cell

190 proteomic experiments with clpC1- and clpP2-depleted Mtb cells suggested that the ClpC1P1P2 complex

191 transcriptome and proteome analyses of NatB-depleted mutants suggested a function of NatB in multipl

192 NPCs have a limited lifespan and are depleted near the time of birth.

193 Mutations in centrosome genes deplete neural progenitor cells (NPCs) during brain deve

194 fic aromatase KO (FBN-ARO-KO) mouse model to deplete neuron-derived E2 in the forebrain and determine

195 We found that depleting neuronal lipin1, a key enzyme controlling the

196 Inhibiting IL-1beta or depleting neutrophils, which both promote invasive infec

197 This mutant has an unusual mechanism as it depletes normal-functioning DNM2 from autophagosome form

198 ntribute to declines in insect herbivores by depleting nutrients from their already nutrient-poor die

199 fected, ART-treated RMs that are selectively depleted of CD8(+) T cells via the CD8beta-targeting ant

200 discrete nanodomains, which persist in cells depleted of CTCF or cohesin, whereas disruption of nucle

201 ratinocytes and organotypic skin equivalents depleted of Dsg1 exhibited reduced Cx43 expression, resc

202 phorylated, but not total, RNAPII, and cells depleted of Elongin A show stronger promoter RNAPII paus

203 ronal cultures of either sex, which had been depleted of endogenous SV2A to mimic the homozygous huma

204 Regulatory regions depleted of H3.3K4A showed histone modification alterati

205 Post-SLIT sera depleted of IgG1 or IgG4 were compared for their IgE-blo

206 hosphorylated, S-nitrosylated, oxidized, and depleted of its stabilizing subunit calstabin-1 6 hours

207 Forced expression of SOCS1 in macrophages depleted of METTL14 or YTHDF1 rescues the hyper-responsi

208 Notably, in 3xTg-AD mice depleted of NK cells, microglia demonstrated a homeostat

209 In Ifitm3(-/-) B cells, lipid rafts were depleted of PIP3, which resulted in the defective expres

210 cial for the function of an organism will be depleted of such variants in natural populations, wherea

211 nduced pluripotent stem cell-derived neurons depleted of TDP-43, but not in those with pathogenic TAR

212 nase as a therapeutic vulnerability in cells depleted of the ATRX chromatin remodeler gene.

213 nd regions that span an AT-rich core and are depleted of the canonical histone H3.

214 of the respiratory chain in human cell lines depleted of the catalytic complex IV subunit COX1 or COX

215 copy (TEM) on wing imaginal discs temporally depleted of the ESCRT-III core component Shrub.

216 Depleted oilfields provide an immediate option for stora

217 to therapeutic strategies for inhibiting and depleting oncogenic RAS proteins.

218 fore differentiation into ForB decorated and depleted ones.

219 As expected, EXOSC10-depleted oocytes have impaired endomembrane components i

220 njection of recombinant DAZL protein in DAZL-depleted oocytes rescues the translation and maturation

221 his plasticity has led to notable efforts to deplete or repolarize tumor-associated macrophages.

222 and miRNA inhibitors that were significantly depleted or increased after repopulation.

223 rvival in KRAS-mutant cancers; therefore, we depleted or inhibited MAP3K19 in KRAS-mutant cancer cell

224 lar sclerosis, mixed cellularity, lymphocyte-depleted or lymphocyte-rich HL), which account for the m

225 , particularly when other sensory inputs are depleted or otherwise compromised.

226 We have shown previously that ATXN3-depleted or pathogenic ATXN3-expressing cells abrogate p

227 of krill at the ice edge indicated they were depleted or were responding to increased predation and/o

228 nobacterial blooms produce hazardous toxins, deplete oxygen, and secrete compounds that confer undesi

229 Southeast Asia, seasonally and interannually depleted oxygen isotope ratios in precipitation have bee

230 RLPs as postlipolytic partially triglyceride-depleted particles derived from chylomicrons and VLDL th

231 rological and immunological data of a B-cell depleted patient treated with obinutuzumab for follicula

232 Interestingly, NRP-1-depleted patient-derived GBM xenografts substantially pr

233 sive activity is promoted by G proteins that deplete phosphatidylinositol 4,5-bisphosphate.

234 organization of oncogenic K-Ras and H-Ras by depleting phosphatidylserine (PtdSer) and cholesterol co

235 ior research indicates ambient heat exposure depletes physiological and cognitive resources, but thes

236 ite precipitation in the presence of a (34)S-depleted pore water sulfide reservoir, via closed system

237 show that the actin-membrane linker ezrin is depleted prior to protrusion onset and that perturbation

238 l a 'disarming' strategy of neutrophils that depletes protein stores to reduce the magnitude of infla

239 c strategy termed "targeted chemotherapy" by depleting protein phosphatase 2A (PP2A) or its inhibitio

240 tween enriched proteins binding strongly and depleted proteins binding marginally, while highlighting

241 used an in vitro assay combining a ribosome-depleted rabbit reticulocyte lysate and ribosomes prepar

242 AS binding proteins inhibit RAS activity and deplete RAS proteins through an autophagosome-lysosome-m

243 we defined a specific nucleosome/nucleosome-depleted region structure that restricts HO activation t

244 distance between heterochromatic nucleosome-depleted regions (NDRs), which is predicted to affect lo

245 els the +1 nucleosome to generate nucleosome-depleted regions during gene activation(9).

246 which has seven chromosomes, and histone H3 depleted regions in Malassezia slooffiae and Malassezia

247 ich explains how INO80 can define nucleosome-depleted regions in the absence of other factors(2).

248 the fast-growing S. mutans creates nutrient-depleted regions that affect the survival and metabolic

249 unusually low bendability within nucleosome-depleted regions upstream of transcription start sites (

250 osomes and this signal, have wide nucleosome-depleted regions, and are more enriched for core promote

251 ility of FFPE-derived RNA, we performed ribo-deplete RNA extractions on > 3200 FFPE slide samples; 25

252 been developed to detect circRNAs from rRNA-depleted RNA-seq data based on back-splicing junction-sp

253 an inducible auxin-degron system to rapidly deplete RPB1 (the largest subunit of RNA Pol II) in livi

254 ltransferase 1 activity, but only chloramine depleted SAM, suggesting that removal of substrate was t

255 Depleting senescent HSCs by 'senolytic' treatment with d

256 response/DNA repair regime that when acutely depleted sensitize FANCJ CRISPR knockout cells to a low

257 We used UNCALLED to deplete sequencing of known bacterial genomes within a m

258 o methods for preparing ribosomal RNA (rRNA)-depleted sequencing libraries for RNA-Seq of whole blood

259 Tumors from women with RCC were nutrient-deplete, showing enhanced energy production to fuel aspa

260 In this study, we show that depleting SIRPalpha (SIRPalpha(-/-)) in mice during TLR9

261 d to alter phosphate transport in intestinal-depleted Slc34a2-deficient mice.

262 CasRx) is an effective and precise system to deplete specific mRNA transcripts in zebrafish embryos.

263 ulum (SR), and another, with open RyRs and a depleted SR.

264 egulatory domain, produced opaque seeds with depleted starch reserves.

265 ct of a PE diet on FAM; in contrast to lipid-depleted starved animals, PE-fed caterpillars maintain l

266 mechanism of action (i.e., requiring an iron-depleted state) and due to differences in interpretative

267 t abilities to rescue MDC formation in ERMES-depleted strains and are incapable of rescuing MDC forma

268 encing to characterize neurogenesis by Notch-depleted striatal astrocytes in vivo.

269 Behaviorally, 5-HT depleted subjects demonstrated impaired social reward le

270 Chlorofluorocarbons (CFCs) are ozone-depleting substances previously thought to be persistent

271 rctic stratosphere due to emissions of ozone-depleting substances(9-11).

272 FcRn binding, half-life, or their ability to deplete target cells in FcgammaR/FcRn humanized mice.

273 Continuation of this trend would deplete the basin and cause significant socio-economic c

274 uring the TMT labeling as a decoy reagent to deplete the excess amount of TMT reagent.

275 hile broad-spectrum antibiotic treatment (to deplete the intestinal microbiota) did not alter the res

276 single 30 ms step to 0 mV was sufficient to deplete the membrane-proximal vesicle pool, while trigge

277 the dominant ALDH isoform in high AVS HNSCC depleted the CIC pool in vitro and in vivo.

278 Sunlight depleted the pool of aromatic compounds that supported m

279 degeneration, displays NADase activity that depletes the key cellular metabolite, NAD+, in response

280 noradrenaline from sympathetic nerves, which depletes the stem cells that give hair their color.

281 hosphoinositide is conventionally studied by depleting the corresponding lipid kinase.

282 f Rapamycin Complex 1 (mTORC1) signalling or depleting the key metabolic substrate glutamine, which d

283 ral organ - skeletal muscle - by selectively depleting the protein in only this tissue.

284 nd human astrocytes to functional neurons by depleting the RNA-binding protein PTB (also known as PTB

285 ivity of CCT2 (CCTbeta) by overexpressing or depleting the subunit in breast epithelial and breast ca

286 teractions within an activated myofibril and depleting the thick filaments in one sarcomere unexpecte

287 hatase Ppx1 to the vacuole and concomitantly depleting the two endopolyphosphatases (ppn1Deltappn2Del

288 th broad-spectrum antibiotics for 4 weeks to deplete their gut microbiota.

289 tion to immunosuppressive treatment and cell-depleting therapies that might increase susceptibility t

290 n (HDL) receptor as a target for cholesterol depleting therapy, we treated lymphoma cell lines known

291 erapy, which is now available to selectively deplete these cells.

292 h, pathogen thalli become increasingly lipid-depleted; they subsequently tend to become entirely abor

293 ons and to regulate the expression of CG/CHG-depleted transposons.

294 antoic Membrane (CAM) in vivo model, lincNMR-depleted tumors are significantly smaller.

295 hese findings, the expression profile of MDK-depleted tumors was enriched in key indicators of a good

296 flammation and plaque regression, Tregs were depleted using CD25 monoclonal antibody in atherosclerot

297 s transcriptional binding partner, ARNT were depleted using siRNA to determine their role in activati

298 Reduction of Treg cells with a depleting version of the same CD25 Ab permitted CD8(+) e

299 Sinking into oxygen depleted waters explains the exceptional soft tissue pre

300 e accept the more disputed evidence of (13)C-depleted zircon deposits.