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1 nucleosides, alcohols, purine and pyrimidine derivatives).
2 iol, which is synthesized from a cholesterol derivative.
3 oxidation of a tetrahydrofuranyl-2-aldehyde derivative.
4 ylpalladium species into a chiral norbornene derivative.
5 were observed for phlorizin and a quercetin derivative.
6 by obtaining an X-ray crystal structure of a derivative.
7 , or direct metalation of 4-azadiene-1-amine derivatives.
8 and deliberate exposure to fentanyl and its derivatives.
9 was subsequently used to design new chromone derivatives.
10 yl chlorides including biologically relevant derivatives.
11 eported previously in relation to stevioside derivatives.
12 several highly functionalized pharmaceutical derivatives.
13 dine and hetisine natural products and their derivatives.
14 ield colored, hydrocarbon-soluble polyolefin derivatives.
15 his cavity, precluding uptake of glutathione derivatives.
16 738 cm(-1), proper for these types of starch derivatives.
17 he practical synthesis of a library of these derivatives.
18 ntioxidant efficiency of the more lipophilic derivatives.
19 PA), and three high-throughput screening hit derivatives.
20 nd styrenes to prepare stilbene and stilbene derivatives.
21 , allowing the synthesis of mixed/asymmetric derivatives.
22 y-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide derivatives.
23 dehyde-derived floral volatiles, and tyrosol derivatives.
24 arious bioactive beta,beta-diaryl propanoate derivatives.
25 for excited state deactivation in isoindigo derivatives.
26 ope using substituted aromatic and aliphatic derivatives.
27 nium or B-ammonium boranephosphonate betaine derivatives.
28 more selective synthetic routes for quinone derivatives.
29 elective sp(3) C-H fluorination in terpenoid derivatives.
30 gically characterized Py-5-labeled histamine derivatives.
31 ration and viability of pre-T and pre-B cell derivatives.
32 oxamides with o-tolyl and methylnaphthalenyl derivatives.
33 d aryl esters into their corresponding tolyl derivatives.
34 nprecedented coupling of acetone with phenol derivatives.
35 ndergo a substitution reaction with cysteine derivatives.
36 ydrates, amino acids and indol- and alkaloid-derivatives.
37 ovide the corresponding bis-thiolated indole derivatives.
38 omes from wild-type and mutant S. marcescens derivatives.
39 ed from the cell surface to generate soluble derivatives.
40 A simple self-assembling glutamine amide derivative 1 was initially found to catalyze a model ald
41 rs and the barrier for isopropyl-substituted derivative 10 was experimentally estimated to be 18.7 kc
44 such as glutaric and delta-aminovaleric acid derivatives, 3-arylpiperidines, or other substituted phe
45 erse cyclopropanols and aryl/alkenyl boronic derivatives (39 examples, 65-94% yield) could be achieve
47 4,5]thiazolo[3, 2-a]pyrimidine-3-carboxylate derivatives (4a-i) containing electron-donor and electro
48 system that incorporates the synthetic auxin derivative 5-Ad-IAA and its high-affinity-binding partne
51 In a rat model of RA, the most promising derivative (5c) showed major antihyperalgesic action com
52 Starting from a known beta-methyltyrosine derivative (8), the route utilizes a diastereoselective
53 hydroxylation of the synthesized 9H-fluorene derivatives afforded 9H-hydroxy-functionalized quaternar
54 dentify the first local minimum of the first derivative after treatment start; this point represented
55 tanding of the reactivity of quinone methide derivatives, aiding the future rational design of the re
57 urier-transform-infrared spectroscopy second derivative analyses revealed that permanganate does not
58 t enantiocontrol for alpha-dehydroamino acid derivatives and alpha-enamides (ee's up to >99%) and pro
59 ocycles allow for the formation of multiaryl derivatives and are a preferred choice over de novo synt
60 ion between 2-alkylidene benzo[b]thiophenone derivatives and enones in the presence of the Cinchona a
61 ddition of the corresponding alkenyl boronic derivatives and maleimides or maleic anhydride is descri
63 nt preparation of alpha-aminophosphonic acid derivatives and phosphonopeptides, which are valuable bu
64 f important compound classes, such as ligand derivatives and polyaromatics, and in the late-stage tri
66 ve sites was planned with benzenesulfonamide derivatives and, for the first time, a phosphorus-based
67 phosphatidylcholine (PC, or their lyso-lipid derivatives), and we find that these substrates compete
69 cogen to distinguish iPSCs from their neural derivatives, and the result was verified by the conventi
71 ing, it can be addictive, and several of its derivatives are being investigated as preferable alterna
73 The barriers for the formation of dioxetane derivatives are computed to be higher than 50 kcal mol(-
74 ous amines, alcohols, thiols, and amino acid derivatives are effective nucleophiles, and their produc
75 synthesized chiral naphthalene diimide (NDI) derivatives are excellent electroactive materials for TD
77 zuki-Miyaura couplings of nontriflate phenol derivatives are limited by their intolerance of halides
78 pids namely polyprenols, dolichols and their derivatives are linear polymers of several isoprene unit
81 5alpha-P), pregnanolone, and their synthetic derivatives are potent positive allosteric modulators (P
83 veral synthetic applications of gamma-lactam derivatives are presented including some examples of hig
86 their benzofused systems, and thiazolidinone derivatives are widely recognized as nuclei of great val
87 d their analogs, along with alkynyl carbonyl derivatives, are the classes of substrates that have ret
91 ly developed agents incorporating spiropyran derivatives as the sensing moiety and characterized feat
92 er phenotypes, the development of flavagline derivatives as therapeutic agents has been hampered beca
93 rate enhancements of a difluorinated SNO-OCT derivative, as compared to the parent scaffold, were not
96 r studies suggest that unsymmetrical aniline derivatives bearing electron withdrawing groups are pref
97 for receiving specific 5,10-diheterotruxene derivatives because the universal method suitable for ob
98 ugh accidental ingestion of plants and their derivatives, besides to products of vegetal-animal origi
100 ivalents of the corresponding cyclopropanone derivatives, by alpha-hydroxylation of sulfonylcycloprop
101 nes into the corresponding silylated aniline derivatives, by using a mixture of sodium powder, crown
102 Our results also demonstrate that epoxide derivatives can be formed as intermediates or byproducts
104 n in fibrocytes to that of IL-12p35 in their derivative CD34(+) OF results from the actions of Slit2.
105 multiple cell line models including a LNCaP derivative cell line resistant to the anti-androgen, enz
107 ectrometry (LC-MS/MS) revealed that luteolin derivative compounds comprised an average of 70% of the
108 automeric structure for the major cyclic ASA derivative, confirming the importance of intramolecular
109 hile molecular motion, predicted for several derivatives, could be of interest for the development of
111 This result demonstrates that cryptophane derivatives decorated with a higher number of phenol gro
114 bial activity, and importantly, eight of the derivatives displayed improved aqueous solubility (up to
115 We analyzed the effects of a new purine derivative drug, PDD005, in attenuating mechanisms invol
116 with the MF59-like adjuvant AddaVax, the RBD derivative elicited neutralizing antibodies with an endp
117 was that local application of enamel matrix derivative (EMD) added to papilla reflection/root prepar
118 study, the effect of using an enamel matrix derivative (EMD) as an adjunct to non-surgical periodont
119 mpared with the association of enamel matrix derivative (EMD) with ABG in the management of intrabony
120 lly, the NH proton in the trifluoroacetamide derivative engages in extended H-bond interactions in it
122 ed Recovery After Surgery (ERAS) and various derivative ERPs have been successfully implemented.
123 obtained from 2,5-di(alkoxy)terephthaldehyde derivatives, except for the COF with the longest alkoxy
125 nhancer in HAND2-AS1 (heart and neural crest derivatives expressed 2 antisense RNA1, a noncoding gene
127 nol triflate derived from a Hagemann's ester derivative followed by a stereoselective Crabtree hydrog
128 r to justify the potential of oxidized C(60) derivatives for bio-applications, we investigated their
129 ntal platform comprised of cell and organoid derivatives from human pluripotent stem cells (hPSCs).
130 mably because they generate ribose-phosphate derivatives from products of an unlinked but essential n
131 od for the synthesis of 1,4-dihydroquinoline derivatives from simple and readily accessible substrate
132 ated conditions using a series of amino acid derivatives gave (3-8, 19, and 34) in 30-74% yield and i
134 eonidin, three cyanidin and two pelargonidin derivatives glycosylated with sophorose and/or glucose a
138 lic aluminyl anion is feasible, a handful of derivatives have been developed to date, which are, howe
147 ns on EMB in its nucleotide-free state and a derivative homology model containing 61 amino acid subst
148 Hence, we present hydroxytyrosol synthetic derivative HT C6 as a new antiangiogenic compound and as
149 antly, due to the greater solubility of this derivative in pure water, we show for the first time tha
150 urthermore, crystal structure analyses of 12 derivatives in complex with Leishmania major NMT reveale
152 ates to afford (E)-diazoaryl-benzo[b]azepine derivatives in excellent yields (89-99%) and with high d
153 of methylated, glucuronidated, and sulfated derivatives (in total, 21 derivatives were identified).
154 netic subdivisions and corresponding nuclear derivatives, in the context of local tract landmarks.
155 Noticeably, starting from o-nitroaniline derivatives, in the presence of alcohols, benzimidazoles
156 nation of electronically diverse aryl halide derivatives, including the bioactive molecules vismodegi
158 f furylated drugs and acetylenedicarboxylate derivatives, initiating the downstream release of the sm
159 report the synthesis and screening of lipid derivatives inspired by granadaene, which reveal feature
161 served that the inclusion of a d-glucosamine derivative into the hydrophobic cavity of beta-CD increa
162 vailable inert electrophiles, such as phenol derivatives, into the corresponding trifluoromethylated
166 first synthesis of a complete set of cation derivatives is to discover highly stable cations, which
169 ochemistry can be observed for cinnamic acid derivatives, leading to the delivery of the copper to th
170 ecular packing of a thiophene-functionalized derivative leads to efficient triplet pair separation, g
171 enome-Wide Association Study (GWAS) of DT696 derivative lines from 72 crosses based on multi-environm
174 histamine was synthesized and the glucosidic derivative N-caprylhistamine-beta-glucoside was isolated
175 inhibited by sulfonamide and tetrazole-based derivatives, NDM-1 by compounds bearing a thiol, a thios
176 Among those tested, diflunisal, a salicylate derivative not previously identified to have anti-folate
177 t-mediated prodrug activation of a propargyl derivative of 5-FU was shown in a colorectal zebrafish x
179 work is aimed to synthesize a new UV active derivative of alpha-lipoic acid (ALA) by its esterificat
180 n vitro and in vivo of a human IgG1 chimeric derivative of MAb 2C7 (2C7-Ximab) with a complement-enha
181 st potent agonists, including 21 and a close derivative of melatonin, 28, had dramatically reduced ar
182 these new adjuvant candidates, VSA-2 (5b), a derivative of Momordica saponin (MS) II, showed consiste
183 ] (Pd(24) ) can be considered as a bicapped derivative of Pd(16) with a tetra-palladium-oxo unit gra
186 of glutathione persulfide (GSSH/GSS(-)), the derivative of the abundant cellular thiol glutathione (G
189 tioxidant activity, the content in coumaroyl derivatives of anthocyanins and the vitisins A and B wer
191 ple access to a vast range of difluoromethyl derivatives of current interest to pharmaceutical, agroc
192 octadecamonoenoic acids (EpOMEs) are epoxide derivatives of linoleic acid (9,12-octadecadienoic acid)
193 s' (ROS) is an umbrella term for an array of derivatives of molecular oxygen that occur as a normal a
195 rs, as-yet-uncharacterized biochemicals, and derivatives of neuromodulatory drugs as important areas
197 ater solubility, various polyethylene glycol derivatives of the distally binding piperidin-4-yl moiet
198 s study, we report the development of cyclic derivatives of the immunomodulatory and antibiofilm inna
199 tic approach also allows access to unnatural derivatives of the natural product, which would not be a
201 hylene and difluoromethylene monophosphonate derivatives of the PAg (E)-4-hydroxy-3-methyl-but-2-enyl
202 ide) regulates the production of avermectin, derivatives of which are used in the treatment of river
204 the ECS and the effects of cannabis and its derivatives on gastrointestinal and hepatic function in
205 synthesis of 2,3,6,7-substituted anthracene derivatives, one of the most challenging anthracene subs
206 , P=0.041], certain chemotherapies [platinum derivatives; OR, 3.0, P=0.034], and a history of radiati
207 g low-kappa materials (such as silicon oxide derivatives, organic compounds and aerogels) have kappa
208 ,4]triazino[5,6-b]indol-5(3H)-yl)acetic acid derivatives (OTIs), designed by molecular modeling and d
209 lar recognition properties of pillar[n]arene derivative P[6]AS, which we refer to as Pillar[6]MaxQ al
210 adiative decay of the anthracene-substituted derivatives, perhaps because of inter-arene torsions tha
211 coverage procedures, including enamel matrix derivative, platelet-derived growth factor, platelet con
214 f-renew and differentiate into multiple cell derivatives provide platforms for drug screening and pro
216 formation of 1,3-enyne or 1-chloro-1,3-enyne derivatives, respectively; the reaction follows an unort
217 tem cells are kept inactive by the vitamin A derivative retinoic acid, which is synthesized and degra
218 constituted with a human alpha-satellite DNA derivative revealed both DNA ends to be highly flexible,
219 d the activity profiles of three epibatidine derivatives, RTI-36, RTI-76, and RTI-102, which have aff
220 e elimination to form the bis-cyclometalated derivatives [Ru(PPh(3))(C(6)H(4)PPh(2))(2)H][M'] where [
221 a new series of LPA(1) agonists among which derivative (S)-17 (UCM-05194) stands out as the most pot
222 a5-subunit-containing GABA(A) receptors, the derivative SH53d-acid shows superior (>40-fold) affinity
226 s with Bocillin FL, a fluorescent penicillin derivative, showed increased beta-lactam binding affinit
231 ion to ketones, aldehydes and other carbonyl derivatives, such amides, ester and carboxylic acids, ar
232 as well as in the tyrosol and hydroxytyrosol derivatives, such as oleocanthal, oleacein, and elenolic
233 Herein 64 examples of beta-alkylated styrene derivatives, synthesized through the reactions of readil
234 series of water-soluble ferrocenylquinoline derivatives, targeting Leishmania donovani, among which
235 ution of a zinc tetraphenylporphyrin (ZnTPP) derivative terminated with an Ipa anchor group (ZnTPP-P-
236 rmacokinetic-optimized, metabolically stable derivative that induced growth delay in a neuroblastoma
238 (1->3) thiodisaccharides led to a family of derivatives that could be used as building blocks for th
239 ed the monomeric LPL/GPIHBP1 complex and its derivative, the LPL-GPIHBP1 fusion protein, with the goa
240 roles in the morphogenesis of PAAs and their derivatives, the aortic arch artery and its major branch
241 le for pursuing enantiomerically pure RJW100 derivatives: they establish RR-RJW100 as the stronger LR
242 a broad range of the desired rubazonic acid derivatives through oxidative diazidation combined with
243 form provides expedient access to a range of derivatives through subsequent elaboration of the xantha
244 arylidene-9H-fluorene/arylideneindolin-2-one derivatives to afford highly substituted bisperoxides wi
245 allyl alcohols at the C-4 position of indole derivatives under the C-H activation conditions catalyze
246 nes, namely, phenols, naphthols, and anisole derivatives, under mild reaction conditions, is describe
248 for the C(7)-H functionalization of indoline derivatives using first-row transition-metal cobalt has
249 iron-catalyzed hydromagnesiation of styrene derivatives using TMEDA has provided molecular-level ins
251 r cyclization, leading to benzo[b]fluorenone derivatives via a radical intermediate as supported by E
252 ivity of the longest oxa[19]helicene dithiol derivative was studied by the scanning tunneling microsc
256 phenolic acids, catechin and some quercetin derivatives was also favored by calcium, while other fla
257 A wide scope of N-arylimine and quinoline derivatives was demonstrated and good efficiency was obs
261 adenocarcinomas to aggressive neuroendocrine derivatives - was initially described in lung cancers ha
262 king with a model, a pentamethyl-substituted derivative, we found that the mutual orientation of two
263 (E(2))] and angular triphenylethylene (TPE) derivatives-we have synthesized a small series of compou
268 ifferent recombinant GCSF-based homo-dimeric derivatives were evaluated by total internal reflection
269 log D) and hepatic stability of several AOXD derivatives were experimentally determined and found tha
271 series consisting of new polyaminoisoprenyl derivatives were prepared in moderate to good chemical y
272 and methylbenzotriazole (MeBT), where these derivatives were sorbed to different types of granular a
274 her amount of ellagitannins and ellagic acid derivatives when compared to the 'Tulameen' cultivar und
275 ically-defined bis-tetrahydrofuran (bis-THF) derivative, which is one of the key structural elements
276 ective enzymatic re-acylation of glucosamine derivatives, which can introduce new stable functionalit
277 high nucleophilic reactivity of benzofuroxan derivatives, which has been related essentially to two f
278 thetic utility of cyclopropanols and related derivatives, which have emerged as unique three-carbon s
279 n effects are observed for ortho-substituted derivatives, which undergo a rapid decomposition associa
280 protocol to access 7-amino-4-methylcoumarin derivatives will find use toward the development of new
281 aromatic acids, anhydrides, and acrylic acid derivatives with 4-hydroxy-2-alkynoates have been disclo
283 eaction generates gamma,gamma-diarylcarbonyl derivatives with alpha-secondary, tertiary, and quaterna
284 catalytic beta-scission of aliphatic alcohol derivatives with both aryl and alkyl halides is disclose
286 analogues of the corresponding cyclopentane derivatives with fixed envelope conformation of the five
287 Novel 1-(1-benzoylpiperidin-4-yl)methanamine derivatives with high affinity and selectivity for serot
288 tructure-assisted design of future A9g-based derivatives with improved binding and stability characte
289 rical annulation of 3-O/N-allyl benzoic acid derivatives with isocyanates for the construction of dih
290 Addition of the surface-bound phosphonate derivatives with L = 4-pyridyl phosphonic acid or diethy
292 ckel-mediated trifluoromethylation of phenol derivatives with readily available trimethyl(trifluorome
293 Sorption coefficients for 14 benzylamine derivatives with systematic differences in compound stru
294 It was demonstrated that tetrahydrofuran derivatives with the benzoxime group (EWG = CHNOBn) are
296 so, it uses exclusively N-alkyl nicotinamide derivatives, without being able to recognize NADH, the r
297 involving application of Bacteriochlorophyll Derivative WST-11 mixed with dextran (WST-D) to the epit
300 The crystallographic analysis of two IDT derivatives yielded a highly unusual three-dimensional p