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1 f specialized mesenchymal cells known as the dermal papilla.
2 n interpreting a gradient emanating from the dermal papilla.
3 hought to be determined by the volume of its dermal papilla.
4 rea of the hair cortex and the volume of the dermal papilla.
5 s androgens must regulate is the size of the dermal papilla.
6 large abnormal follicles containing a small dermal papilla.
7 c staining of the nuclei of the cells of the dermal papilla.
8 eceptor was expressed in the hair matrix and dermal papilla.
9 label-retaining cells, descend to the apical dermal papilla.
10 WNT6 and WNT10B, and inhibiting SFRP1 in the dermal papilla.
11 s, including HFSCs, secondary hair germ, and dermal papilla.
12 talized DPCs have high resemblance to intact dermal papilla.
13 ent hair buds also show abnormalities in the dermal papilla.
14 es, namely epithelial matrix and mesenchymal dermal papilla.
15 ndrogenetic alopecia by interfering with the dermal papilla.
16 b expressed markers of the dermal sheath and dermal papilla.
17 the diffusible IGF antagonist Igfbp3 in the dermal papilla.
18 o detect genes specifically expressed in the dermal papilla.
19 unravel new molecular landscapes within the dermal papilla.
20 populate a papillar ectoderm niche near the dermal papilla.
21 base of rete ridges or overlying the tip of dermal papilla.
23 thought to be controlled by signals from the dermal papilla, a specialized cluster of mesenchymal cel
25 mean 17-fold greater number of cells in the dermal papilla and a 2.4-fold greater volume associated
26 t the functional lineage restriction between dermal papilla and adipocyte fates is regulated by disti
28 ession of IP-associated genes in cultured HF dermal papilla and dermal sheath cup cells (DSCCs) compa
31 licles exhibited pigment incontinence in the dermal papilla and in selected outer root sheath keratin
32 oughout the murine hair cycle, including the dermal papilla and lower epithelial strand of late-catag
33 hifts in noncoding regions also included the dermal papilla and matrix regions of the hair follicle t
35 supported by reduced proliferation of human dermal papilla and predominantly epithelial keratinocyte
37 ic cartilage, connective tissue fibroblasts, dermal papilla and sheath cells, and adipocytes in the a
38 trix expressed SUR1 and Kir6.2, whereas both dermal papilla and sheath exhibited SUR2B and Kir6.1.
39 gest that onychodermis is the counterpart of dermal papilla and that BMP5 in onychofibroblasts plays
40 olled by reciprocal interactions between the dermal papilla and the surrounding epidermal hair precur
41 o correlated with the number of cells in the dermal papilla and with the volume of dermal papilla per
42 d in the outer root sheath, sebaceous gland, dermal papilla, and connective tissue sheath of human an
43 romote the formation of a tightly aggregated dermal papilla, and/or protect the dermal papilla cells
44 interactions that lead to the formation of a dermal papilla anlage and ingrowth of the epidermis.
45 Further, IGF-I receptor expression by the dermal papilla appears to be switched off during the tra
47 Melanocyte stem cells more distant from the dermal papilla are unscathed, thereby preventing hair gr
48 estricted to the hair matrix surrounding the dermal papilla, are found in the precortex and hair shaf
49 pled receptor kinase 2 deletion displace the dermal papilla away from the bulge and promote irreversi
50 stem cell homeostasis beneath the stem cell-dermal papilla-based epithelial-mesenchymal interaction
52 0 years revealed many previously undescribed dermal papilla, bulge SC, and hair germ SC genes in mous
53 ll transcriptomics established signatures of dermal papilla, bulge SCs, and hair germ SCs, but low de
54 e located in the key follicle regulator, the dermal papilla, by analyzing individual follicular struc
62 that the comparison of the mRNA of cultured dermal papilla cells and fibroblasts can lead to the ide
63 d a previously unrecognised heterogeneity in dermal papilla cells and shown that Sox2-positive cells
65 in large quantities in cultured rat vibrissa dermal papilla cells but undetectable in cultured rat sk
66 this study was designed to determine whether dermal papilla cells cultured from human hair follicles
67 ptor and/or aromatase expression in cultured dermal papilla cells derived from human hair follicles.
68 P-1 expression was absent from hair bulb and dermal papilla cells during early to mid-anagen but was
69 show that Blimp1 is dynamically regulated in dermal papilla cells during hair follicle (HF) morphogen
70 from neonatal foreskins and cultured murine dermal papilla cells from adult GFP transgenic mice and
72 ggregated dermal papilla, and/or protect the dermal papilla cells from apoptosis induced by cytokines
74 med global gene expression analysis of human dermal papilla cells in culture and discovered very rapi
75 apitulate this process in humans using human dermal papilla cells in human skin have failed, suggesti
77 imulated and androgen-treated cultured human dermal papilla cells isolated from beard (androgen-sensi
78 uman skin have failed, suggesting that human dermal papilla cells lose key inductive properties upon
79 ed that the osteopontin gene is expressed in dermal papilla cells of pelage follicles during catagen
81 addition, this study supports that cultured dermal papilla cells provide a cell-based model system t
82 n of these genes in cultured beard and scalp dermal papilla cells reflected similar differences in mi
84 y skin keratinocytes and fibroblasts without dermal papilla cells served as positive and negative con
87 this study, we define the transcriptomes of dermal papilla cells, bulge SCs, hair germ SCs, epiderma
88 ens do not stimulate mitogenesis in cultured dermal papilla cells, this study was designed to determi
89 inductive capability, and we show that human dermal papilla cells, when grown as spheroids, are capab
101 reased [3H] thymidine incorporation by other dermal papilla cells; trypsin treatment significantly re
104 nterior-posterior Wnt2b signaling within the dermal papilla controls barbule cell fates with spatiote
106 ) morphogenesis and cycling, the location of dermal papilla (DP) alternates between the dermis and hy
107 in the inner root sheath (IRS), whereas the dermal papilla (DP) and outer root sheath were consisten
109 assembly strategies for the interactions of dermal papilla (DP) cells with adipose-derived stem cell
111 bridization to identify genes induced in the dermal papilla (DP) during anagen as a result of the int
115 ranscription factor Sox2 is expressed in the dermal papilla (DP) of guard/awl/auchene hair follicles
117 and gain of function of beta-catenin in the dermal papilla (DP) of the hair follicle results in yell
118 ranscription factor Tbx18 specifically marks dermal papilla (DP) precursor cells during embryonic hai
120 cILC2s accumulated around the hair follicle dermal papilla (DP) region to facilitate the process.
122 Systematic ablation of previously identified dermal papilla (DP) signature genes in embryonic DP prec
126 by a specialized mesenchymal population, the dermal papilla (DP), that is embedded in the hair bulb.
133 n wound closure, we found that hair follicle dermal papilla fibroblasts could accelerate closure of i
135 polarity, and loss of TGF-beta signaling in dermal papilla fibroblasts leads them to progressively l
136 rough mouse intravital imaging, we show that dermal papilla fibroblasts remodel individually and coll
137 e used a cytokine array to determine how the dermal papilla fibroblasts were eliciting this effect an
139 uctive potential and premature senescence of dermal papilla fibroblasts, or by intraepithelial events
140 Hair follicle stem cells are regulated by dermal papilla fibroblasts, their principal signaling ni
143 sion of selected ones, namely PAPPA2 for the dermal papilla, FOXM1 for the germinative hair matrix, A
144 ompartment ablation and inhibition of mature dermal papilla functions, confirmed by additional single
146 expression in the mesenchymal component, the dermal papilla, has hampered progress towards understand
148 imply that the increase in the volume of the dermal papilla in these follicles is due to an increase
149 sence of ectodermal placode and primodium of dermal papilla in these mice, yet the subsequent hair sh
150 e functional role of Blimp1 in promoting the dermal papilla inductive signaling cascade that initiate
151 limp1 is both a target and a mediator of key dermal papilla inductive signaling pathways including tr
152 lial-fibroblast interface, namely, hair germ-dermal papilla interface, makes asymmetrically organized
154 d et al show that JAK/STAT5 signaling in the dermal papilla is required for anagen onset in the murin
155 lected similar differences in microdissected dermal papilla isolated from intact beard and scalp foll
156 o key compartments (matrix keratinocytes and dermal papilla) leads to dynamic instabilities in the po
158 uce hair growth independently of mesenchymal dermal papilla niche signals normally required for hair
159 he new follicles formed sebaceous glands and dermal papilla, normally established only in embryogenes
163 the epidermis (Lef-1, beta-catenin, Shh) and dermal papilla (p75 kDa neurotrophin receptor, alkaline
166 reas Aldh1a3 expression was primarily in the dermal papilla, pre-cortex, and hair shaft during mid-la
167 with their remodeling fibroblast niche, the dermal papilla, providing a powerful model to functional
168 cate an estrogen receptor pathway within the dermal papilla regulates the telogen-anagen follicle tra
169 association studies signals are enriched in dermal papilla regulatory regions, supporting the role o
170 s, precursors of adult HF stem cells and the dermal papilla/sheath niche, along with lineage-related
172 Furthermore, we pinpoint KIT-ligand as a dermal papilla signal promoting melanocyte stem cell dif
174 oth BAB and BAN retained high proportions of dermal papilla signature gene and versican protein expre
175 these genes, sfrp-2 has been identified as a dermal papilla signature gene in mouse pelage follicles.
176 ctors may be involved in the key increase of dermal papilla size necessary for androgen-induced chang
177 ecause hair size has been clearly related to dermal papilla size, one of the key functions androgens
178 ytes, and BMP signaling positively regulates dermal papilla-specific enhancer of the Agouti gene in p
179 da-A1 expression is required until the early dermal papilla stage for guard hair germs to make follic
181 One forms the upper dermis, including the dermal papilla that regulates hair growth and the arrect
184 leads to endogenous EDN3 upregulation in the dermal papilla, the secondary hair germ cells, and the e
185 ndrogens are thought to act primarily on the dermal papilla, these changes may have a direct bearing
186 derived from human and rodent epidermis and dermal papilla to reconstitute hair-follicle mini-organs
188 n large male facial follicles the mean total dermal papilla volume was almost 40-fold higher than in
189 e expression of the estrogen receptor in the dermal papilla was hair cycle-dependent with the highest
190 the outer root sheath, sebaceous gland, and dermal papilla, whereas CCAAT/enhancer-binding protein-b
191 r matrix which forms the hair itself, or the dermal papilla which is responsible for induction of the