ライフサイエンスコーパス: design principle

1 ols are available to apply 1D diffusion as a design principle.

2 n transmission per energy used as a synaptic design principle.

3 ugh decades of work on developing structural design principles.

4 m colloidal structures, guided by biological design principles.

5 of cellular metamaterials based on Kirigami design principles.

6 eriving general and straightforward catalyst design principles.

7 grown on LaAlO3 (111) substrates fulfil the design principles.

8 yotes or bacteria, little is known about the design principles.

9 ting algorithms and exploring lineage tracer design principles.

10 t population-scale models to be explored for design principles.

11 trinsic dispersion of existing materials and design principles.

12 near-eye display based on the "human-centric design" principle.

13 pact on their ability to apply instructional design principles (49%) and present in face-to-face sett

14 to tailor active particles; (2) attempts to design principles according to which active particles in

15 Great strides in understanding the design principles adapted by nature have led to a tremen

16 Here we introduce physical design principles allowing us to define high-order elast

17 r successful implementation, including study design principles, analytical tools and future developme

18 sives detector by applying this bio-inspired design principle and making the device "sniff" like a do

19 the direct correlation between their modular design principle and various interesting properties.

20 This work provides design principles and a universal strategy to construct

21 ecision and analysis procedure incorporating design principles and ability to examine design decision

22 technologies by (i) introducing very simple design principles and assembly protocols; (ii) potential

23 The chemical design principles and cellular mechanisms of action to a

24 or dynamical systems by identifying critical design principles and codifying them into a compiler aut

25 gically relevant chemical space, we identify design principles and connectivity patterns that would p

26 Here, we outline the emerging siRNA design principles and discuss the consequences for siRNA

27 Previous reports exploit diverse design principles and fabrication techniques to achieve

28 Design principles and implementation approaches for frag

29 w provides a pertinent insight into relevant design principles and inspires further research in this

30 Advances in bioinspired design principles and nanomaterials have led to tremendo

31 microscale interfaces, so we expect that the design principles and predictive theory outlined here wi

32 The design principles and predictive theory outlined in this

33 Ring synV chromosome can extends Sc2.0 design principles and provides a model with which to stu

34 mmarizes the current state-of-the-art on the design principles and synthetic strategies toward COFs b

35 ) technologies by enabling fundamentally new design principles and topologically enhanced functionali

36 The underlying design principles and toughening mechanisms of these mat

37 of cancer nanomedicines: (i) physicochemical design principles, and (ii) clinical trial design, which

38 um ion transport, key evaluation parameters, design principles, and key materials.

39 ogical networks is the key to understand the design principles, and to infer governing mechanisms of

40 Therefore, cortical design principles appear to enhance coding accuracy by r

41 ystematically present material synthesis and design principles, applications, and challenges and oppo

42 Design principles are also established for some of the C

43 The workflow design principles are applicable to other genomic data t

44 These design principles are considered in the context of surfa

45 Alloy design principles are described along with the structure

46 These design principles are especially valuable for small syst

47 The proposed design principles are essential for design and implement

48 y of suitable materials, and new chromophore design principles are needed.

49 ure of SHE, we demonstrate that two of these design principles are weak crystal fields and the presen

50 of this Review will be predominantly on the design principles around the construction of temperature

51 nocrystals) with both top-down and bottom-up design principles at the submicron level.

52 Here we introduce a new design principle based on preassembled components of the

53 his understanding significantly differs from design principles based on ex situ characterization tech

54 Persistence of this design principle becomes apparent after the material pro

55 f PbSc(0.5)Ta(0.5)O(3), then the established design principles behind magnetocaloric heat pumps could

56 phosis and mammalian puberty exhibit similar design principles, but the conservation of molecular com

57 The work presented here uncovers the design principle by which it is possible to decode calci

58 is Tutorial Review, we discuss the different design principles by which molecular machines can be eng

59 into physicochemical signals based on logic design principles can be a powerful means for the develo

60 study demonstrating how reticular chemistry design principles can be extended to conductive framewor

61 The reported design principles can be extended to construct higher-or

62 With novel design principles, CDAPS addresses unmet new challenges,

63 ight developmental regulatory mechanisms and design principles common to these lineages.

64 The design principles constrain the set of configurations th

65 ons suggests that systems employing the same design principles could be implemented in other host org

66 Here we begin to explore how selective design principles deduced from spin-based systems could

67 Molecular design principles demonstrated here could have broad imp

68 are supported by experimental data, and the design principles derived from the descriptors provide a

69 The rational design principle described herein could potentially be e

70 nile rat somatosensory cortex suggest common design principles, despite the particular morphological

71 eties beyond conventional CB and SB based on design principles developed from these simulation studie

72 However, because of the lack of design principles, developing such smart microorganisms

73 The design principles dictating the spatio-temporal organisa

74 Following a materials design principle drawn from broad structural analogies t

75 Insight into molecular electrocatalyst design principles emerge from this study.

76 We also outline design principles, employing both intramolecular and int

77 ection by taking advantage of the structural design principles evolved by nature.

78 However, relatively few predictive design principles exist that permit both rational and mo

79 n be implemented using model-view-controller design principles, existing genome browsers, and existin

80 This unique design principle exploits liquid-liquid interface as a p

81 This work presents a design principle for a material that gains unique proper

82 he basis of our results, we derive a general design principle for acid CO(2) electrolyzers to suppres

83 This work addresses a fundamental design principle for constructing molecular wires where

84 [CpMo(H2)(CO)(P2N2)](+) isomers, providing a design principle for controlling heterolytic cleavage of

85 We report a new molecular-design principle for creating double-gyroid nanostructur

86 ance sheds light on the effectiveness of the design principle for developing safe and stable Li metal

87 tein and peptide self-assembly is a powerful design principle for engineering of new biomolecules.

88 on of the photoconductance leads to a simple design principle for enhancing the performance of molecu

89 s theory is a special case of an overarching design principle for icosahedral, as well as octahedral,

90 g-runout landslides, and can be couched as a design principle for low-friction interfaces.

91 discuss the classification of and propose a design principle for mechanical metamaterials that can b

92 cores cooperativity and synergy as a general design principle for multiobjective optimization in biol

93 suggest random sparse connectivity as a key design principle for neuronal computation.

94 the generality of this in situ approach and design principle for next-generation dendrite-free batte

95 ial organization can be a similarly powerful design principle for overcoming limitations of speed and

96 To exploit this potential, a design principle for percolation networks of technologic

97 Herein, an important design principle for perovskite LEDs is elucidated regar

98 Herein, we report a general design principle for pH-responsive DNA motifs for genera

99 roof-of-concept for, to our knowledge, a new design principle for protein-DNA recognition in the huma

100 This protocol describes a rational design principle for Si-based structures, general proced

101 talysts are often considered as the ultimate design principle for supported catalysts, due to their u

102 The strategy provides a general design principle for synthesizing abiotic polymer inhibi

103 hesin-dockerin interaction is now a standard design principle for synthetic biology(2,3).

104 Here, we report a design principle for the creation of a selective yet rob

105 We identified the structural design principle for this divergence: Insertions at key

106 We explore the design principles for a functional lattice made of 2D po

107 These elements may provide design principles for a generic mechanosensory protein m

108 ting a comprehensive theory of five rational design principles for achieving giant intrinsic SHE in t

109 Design principles for anti diastereomer derivatives are

110 synthetic biology should develop predictive design principles for biological systems operating in co

111 This protocol discusses design principles for CARs responsive to soluble ligands

112 inant genes provides unique insight into the design principles for constructing useful synthetic asse

113 These findings led to a set of new design principles for creating antifouling topographies,

114 Here, we establish the chemical design principles for creating materials with this behav

115 unds and allow for establishing quantitative design principles for efficient TPA materials.

116 anding of the phenomena as well as potential design principles for engineering magneto-optical and op

117 The design principles for engineering plasticity described c

118 Additionally, we derive three other design principles for enhancing SHE.

119 e that such modular vaccine strategies offer design principles for enhancing the immunogenicity of pr

120 Design principles for fullerene-free acceptors remain un

121 ave also provided key insights into chemical design principles for future classes of MCC-based anolyt

122 These findings suggest a set of new design principles for gene delivery by the synergistic c

123 mutants, we identify the general underlying design principles for generating stochastic transcriptio

124 tochastic thermodynamics, we derive a set of design principles for growing controlled assemblies far

125 Our work offers design principles for how nonequilibrium fitness "seasca

126 Our findings establish the design principles for improved glycan conjugate vaccines

127 he identification and application of generic design principles for improving palliative care in the E

128 its on their operational characteristics and design principles for improving performance, and discuss

129 Our results highlight new design principles for long T1 and T2 times by demonstrat

130 hemicellulose-based materials may offer new design principles for material formulations.

131 Our findings provide general design principles for multistep cell linage transitions

132 Our concepts propose design principles for networks predicting how behavior a

133 materials and highlight electrode structure design principles for obtaining the desired electrochemi

134 tion and nanoscale morphology in elucidating design principles for OECT operation.

135 phasic shape dependence, leading to catalyst design principles for optimal reactant adsorption effica

136 dings provide possibilities in advancing the design principles for photo-rechargeable lithium ion bat

137 First the design principles for polymer-drug conjugates are discus

138 These results offer design principles for potential MOFs candidates for urem

139 nd metal oxide component, and we set out the design principles for producing high-selectivity Pd-base

140 This work offers design principles for programmable biochemical reactions

141 Our findings offer design principles for programming efficient transport in

142 AL metabolic regulation, but also elucidated design principles for ratio-sensing signal processing th

143 , when compared to other mechanisms, (2) new design principles for rationally designing PTM systems f

144 experimental refactoring, identifying simple design principles for rationally tuning the dose respons

145 This discovery points to new materials design principles for scalable valleytronic devices and

146 From these findings, we formulate design principles for simultaneous optimization of built

147 Facing enormous chemical space and unclear design principles for small-molecule combinations, compu

148 windows, and are not constrained to previous design principles for sulfide and oxide Li-ion conductor

149 ation therapy, and provide new insights into design principles for tailor-made nanomedicine platforms

150 ient catalysts, it is necessary to establish design principles for the carbon-based catalysts.

151 d electrochemical stability, and provide the design principles for the development of air-stable soli

152 ing effective models, here we outline simple design principles for the optimization of shift currents

153 The basic design principles for the preparation of highly luminesc

154 lid electrolyte, which can be used to derive design principles for the preparation of related oxide i

155 he cursor control setting, but the available design principles for these decoders are such that it ha

156 We sought to establish design principles for this class of biosensor by charact

157 ng has the potential to introduce additional design principles for transition-metal complexes, with i

158 alignment, providing alternative instrument-designing principles for atomic force microscopy-based i

159 he final aim of aiding in the development of designing principles for catalysts with a broader scope.

160 The analysis indicates that bioinspired design principles from ecosystems can lead to both envir

161 hape mapping opens up new ways to understand design principles, functions, and evolution of proteins.

162 ity of reflectins as the centrally important design principle governing biophotonic tunability in thi

163 Origami- and kirigami-based design principles have recently received strong interest

164 odern quantum chemical methods to understand design principles how the structure of tertiary amine ca

165 We demonstrate that this molecular design principle, i.e., incorporation of sterically dema

166 gain advantages from three general and basic design principles: (i) Compact representation of the lon

167 Our analysis suggests a new design principle in controlling cellular plasticity thro

168 tituent mechanism, can serve as an effective design principle in controlling the interaction strength

169 Establishing an effective design principle in solid-state materials for a blue-lig

170 powerful tool to predict and decode circuit design principles in an unbiased manner, and to quantita

171 way towards real-time analysis of materials design principles in devices as they actually operate.

172 ified designed sequence is crucial to verify design principles in genome synthesis.

173 The increasing popularity of biomimetic design principles in nanomedicine has led to therapeutic

174 This revealed novel design principles in synthetic biology and demonstrated

175 ructural catalyst motifs and inspired unique design principles in this field.

176 s in dissipative gases and can lead to novel designing principles in particulate systems.

177 By implementing biological design principles into glass-based materials at the micr

178 Here, the design principle is demonstrated by cyclometalation with

179 nction-oriented organic synthesis, a general design principle is presented to build high-performance

180 Its guiding design principle is that the target structure is the sin

181 quantitative understanding of the underlying design principles is still lacking.

182 The work describes the design principles, large hydrophobic P3 residue and smal

183 gether, the simulations reveal the molecular design principles linking redox reactions to quinone tur

184 olecular and synthetic biology is to uncover design principles linking RNA structure to function to u

185 estable predictions provides insights into a design principle of biological clockwork, with implicati

186 Here we present a design principle of carbon supports, utilizing self-asse

187 A common design principle of heteromeric signaling proteins is th

188 This simple and effective design principle of host-guest interactions driven fluor

189 rd these compounds is described based on the design principle of iron(III)-catalyzed carbonyl-olefin

190 The design principle of NDP-V is to reduce the conformationa

191 Our results uncover a simple design principle of organ growth where progenitors and d

192 Thus, the results suggest an important design principle of separable contributions from ECM pre

193 nd thus provides a structural glimpse of the design principle of the molecular transducer for cold an

194 o-3D printed prototypes demonstrate that the design principle of the peacock spiders' scales could in

195 Design principles of a new class of microwave thin film

196 y serve as a framework for understanding the design principles of a number of types of molecular moto

197 Based on the design principles of a paper-based centrifuge, this 3D-p

198 Our findings provide insight into the design principles of an immunoregulatory checkpoint cont

199 Further, we discuss the design principles of bidirectionality and reversibility

200 The related mechanistic understanding and design principles of carbon-based metal-free catalysts a

201 eview, we explore the common themes and core design principles of cellular clocks, giving special con

202 ing properties have been developed using the design principles of crystal engineering and structure-p

203 We also discuss design principles of different approaches, their utility

204 he GSR will provide crucial insight into the design principles of early stress-response modules and t

205 Directly testing the design principles of how dual-timescale circuits control

206 However, detailed studies outlining the design principles of ILs for transdermal drug delivery a

207 n animals have been studied extensively, the design principles of information processing in such grou

208 c matrix provide important insights into the design principles of lithium metal anodes.

209 d by nature can be achieved by mimicking the design principles of natural photosynthetic proteins.

210 This feature, and other design principles of our work, might enhance the study a

211 Here we analyse in detail the design principles of phoretic pumps and show that for a

212 These findings reveal design principles of protein networks by means of altera

213 l effects on defect dynamics may inspire new design principles of radiation-tolerant structural alloy

214 ng alloy complexity may pave the way for new design principles of radiation-tolerant structural alloy

215 We applied the design principles of speed and accuracy, unattended auto

216 SPT) of the protonated chromophore, we infer design principles of the GFP chromophore as a photoacid

217 We here review the design principles of the scOrange toolbox that support s

218 We also discuss design principles of tools and the role of failure.

219 letes' Village that was repurposed on active design principles, on adult physical activity and adipos

220 The design principle opens a new opportunity to develop high

221 d that indicate the presence of evolutionary design principles or have an overly influential role on

222 ining folding-mechanistic behaviors, and the design principles orchestrating the signal transduction

223 These design principles point the way to the addition of N-H b

224 dashboards developed using the framework and design principles presented here are extensible and cust

225 The design principles presented here will undoubtedly help a

226 The design principles proposed in this work extend to pallad

227 This new design principle provides an effective and versatile pla

228 n R and leveraging Bioconductor software and design principles, provides for the coordinated represen

229 each of which employed different fundamental design principles ranging from a pattern recognition met

230 Together, the data suggest design principles relevant to many developing tissues.

231 NRR), mechanistic understanding and catalyst design principles remain lacking.

232 extended supramolecular macromolecules, and design principles remain nascent.

233 ss-linked polymers in industry, of which the design principle remains unknown [M.

234 We also provide insights into the design principles required for efficient fluorogenic des

235 questions that remain to be addressed to the design principles required for useful applications.

236 as9-based histone deacetylase (HDAC) and the design principles required to achieve locus-specific his

237 a generalist circuit, obeying computational design principles resembling those governing other highe

238 cale, stochastic modeling to investigate the design principles responsible for robust establishment o

239 The design principle revealed by this work can be used to ex

240 Indeed, the "design principles" shaping the optical properties of the

241 These design principles should facilitate the development of i

242 The tool incorporates visualization design principles such as focus+context and visual data

243 cilitate the broader use of these compounds, design principles supported by density functional theory

244 pe and 10 mutant strains, and we uncovered a design principle that describes how architectures make t

245 This reveals an underlying design principle that is maintained across large changes

246 ct manifests tapering symmetry, a felicitous design principle that may have evolved not only to aid t

247 of a new pai-conjugated material, based on a design principle that promises to facilitate spin and ch

248 This finding supports the design principle that semiflexible receptors can facilit

249 the poseidon system and use it to illustrate design principles that can facilitate the adoption and d

250 The fundamental design principles that control the structural determinan

251 ade complex organic materials follows simple design principles that could be exploited to engineer he

252 Learning from the design principles that defined success for the clinicall

253 subtilis to uncover widely relevant general design principles that describe the structure-function r

254 We introduce design principles that enable robust and scalable circui

255 nd energy storage, and discuss the intricate design principles that enable these COFs to perform bett

256 the smallest connectomes (302 neurons), the design principles that explain how the connectome struct

257 We identify four design principles that govern the production of these hi

258 f this Viewpoint is to discuss the molecular design principles that guide development of synthetic an

259 These results reveal molecular vaccine design principles that may be used to drive functional B

260 In this article, we examine whether the core design principles that Ostrom advanced can cultivate sel

261 this selectivity, and comment on the general design principles that should help develop targeted exci

262 Uncovering biochemical design principles that underpin such response dynamics i

263 We show that Ostrom's design principles that were forged in the context of man

264 this assay system to show that a dualsteric design principle, that is, molecular probes, carrying tw

265 Furthermore, guided by the same design principles, the synthesis and applications of mul

266 the cleavable bond location can be used as a design principle to achieve controlled thermoset degrada

267 This work establishes a general design principle to control over ultra-large optical asy

268 udies, we have established a module-swapping design principle to engineer allosteric response and DNA

269 In 1903, Alexander Graham Bell developed a design principle to generate lightweight, mechanically r

270 in prokaryotic genomes, identifies a simple design principle to guide bioengineering and bioinformat

271 However, the fundamental design principle to prepare materials that can convert t

272 In this study, we apply this design principle to synthetic networks, testing whether

273 The translation of nature's design principles to applications in optoelectronic devi

274 r-dynamics simulations, we develop molecular design principles to connect the sequenced charge patter

275 We introduce a set of general design principles to create intricate DNA tessellations

276 ed to take advantage of some set of physical design principles to ensure robust vesiculation against

277 gically diverse teams suggests institutional design principles to help unleash the power of polarizat

278 We use these design principles to predict statistics of the affinitie

279 e the most promising candidate and developed design principles to rationalize why longer alkyl chains

280 ctive materials that do exist are given, and design principles to realize the next generation of mate

281 ently in Nature, using biologically inspired design principles to recapitulate native crypt-villi top

282 We focus on: (1) attempts to formulate design principles to tailor active particles; (2) attemp

283 ications that have been utilized and suggest design principles toward high-mobility indacenodithiophe

284 icrobial activity and establishes innovative design principles toward the development of antimicrobia

285 The design principles underlying biomolecular phase separati

286 The replication in synthetic systems of design principles underlying such structural motifs has

287 of PTX drug delivery systems and analyze the design principles underpinning each delivery strategy.

288 We design principled unsupervised methods to derive hyperpa

289 To develop a GABA sensor, we applied the design principles used to create the fluorescent glutama

290 ct works on CPPs, including basic structural design principles, various synthetic protocols and topic

291 This device is based on design principles we have reported previously for detect

292 Using a modular design principle, we developed genetically encoded, unim

293 Based on this design principle, we experimentally demonstrate waveguid

294 Using this design principle, we generate a ratiometric fluorescent

295 Utilizing this design principle, we have successfully detected the acti

296 Using a similar design principle, we report spectroscopic evidence for t

297 In support of these design principles, we report their successful applicatio

298 Here, we identify a new design principle which has so far been overlooked.

299 We expect these ligand design principles will broadly enable the continued sear

300 ementation of new reporting and experimental design principles will improve experimental work, speed