ライフサイエンスコーパス: destine

1 This modification destines activated caspase-8 molecules to rapid proteaso

2 Diapause-destined adult females and nondiapausing counterparts af

3 pically targeted cargo delivery, for both PM-destined and secretory cargo, providing the first eviden

4 The ASC-destined branch requires induction of IRF4, MYC-target g

5 Subjecting gyne-destined brood to simulated AD-frequency vibrations caus

6 body, galectin-3 colocalizes with melanosome-destined cargo, specifically tyrosinase and Tyrp-1.

7 All outflow tract-destined cells are intermingled with those that will con

8 Our studies identify that KV-destined cells remain interconnected by cytokinetic brid

9 crossovers or non-crossovers, but crossover-destined D-loops may have longer lifespans.

10 de novo DNA methyltransferase to the lineage-destined daughter cell facilitates epigenetic adaptation

11 d potential use of fodder potato protein not destined directly for food purposes as the suitable prod

12 or, and the ability to lay unfertilized male-destined eggs.

13 The dsi-RNA injected diapause-destined female post-adult eclosion were fed for 7 days

14 pping with the growth cones of other neurons destined for a different layer through the redundant fun

15 The developing mammalian brain is destined for a female phenotype unless exposed to gonada

16 icare/Medicaid Services model, and therefore destined for a financial penalty, 6/25 (24%) were reclas

17 is code, the setting differed: beneficiaries destined for a sepsis admission were more likely to have

18 the fate of each mitochondrion, to be either destined for a subsequent fusion or eliminated by autoph

19 espiratory drive to generate late-E activity destined for AbN motoneurones.

20 Embryos in seeds destined for abortion failed to undergo normal morphogen

21 r proteins that recruit cytoplasmic proteins destined for active nuclear import to the nuclear transp

22 Dysplastic ACF, once postulated as the ACF destined for adenomatous transformation, have been rarel

23 ypical childhood neural features among those destined for adolescent remission or the correction of e

24 vivo PI3K-delta inhibition in CD8(+) T cells destined for adoptive transfer, enhancing their survival

25 ertoire of states than are sequence segments destined for alpha-helix.

26 ived from intermediates of the OPPP that are destined for amino acid production, restores wild-type l

27 Although Medicare beneficiaries destined for an inpatient hospital admission with a seps

28 ominantly to convert a RPC subpopulation not destined for an RGC fate to adopt that fate.

29 ptotic cell extrusion." Specifically, a cell destined for apoptosis signals its live neighboring epit

30 During extrusion, a cell destined for apoptosis signals its neighboring cells to

31 ector cells (SLECs), a majority of which are destined for apoptosis, and the memory precursor effecto

32 iew addresses the potential of immunosensors destined for application in food and environmental analy

33 of 24 000 +/- 940 kg y(-1) of microplastics destined for application on US agricultural soils contai

34 ely on the same crops, although the fraction destined for aquaculture is presently small ( approximat

35 dination site for exogenously derived sulfur destined for attachment to the substrate or that the clu

36 information revealed that sequence segments destined for beta-sheet in the final native fold are ene

37 e, whereas structure formation for sequences destined for beta-strand is far less probable.

38 tion and in assuring quality of preparations destined for biomedical applications.

39 ivory price and increased seizures of ivory destined for China.

40 lar structure storing transmembrane proteins destined for cilia during the early phase of ciliogenesi

41 and to examine the metabolic status of iPSCs destined for clinical applications.

42 lapse, without subjecting those patients not destined for CNS relapse to unnecessary and potentially

43 mRNAs, perhaps cotranscriptionally, that are destined for cytosolic degradation as part of the mechan

44 ly equal mitoses the segregation of proteins destined for degradation (Smad1 phosphorylated by MAPK a

45 ER-resident proteins destined for degradation are dislocated into the cytosol

46 They sort proteins destined for degradation into internal vesicles while in

47 Multivesicular bodies (MVBs) deliver cargo destined for degradation to the vacuole or lysosome.

48 tering bulk cytoplasm and/or selected cargos destined for degradation upon autophagosome fusion with

49 hesive junctional PCP complexes appear to be destined for degradation upon internalization.

50 central role in processing cellular proteins destined for degradation, but little is currently known

51 internalized AChRs, which would otherwise be destined for degradation, into synaptic sites.

52 raned autophagosomes that engulf the cargoes destined for degradation, sometimes with the help of aut

53 se aggregated proteins are not misfolded and destined for degradation.

54 ackaging, and transport of synaptic material destined for degradation.

55 The tegument comprises at least 20 proteins destined for delivery into the host cell.

56 in the selection and packaging of the cargo destined for delivery to the cilium.

57 tracking along a subset of tracheal branches destined for destruction.

58 ed axon-glial interactions in those children destined for diagnosis of MS.

59 em cell lineages is that stem cell daughters destined for differentiation undergo several transit amp

60 to exclusively reduce disulfides in proteins destined for dislocation to the cytosol for degradation.

61 oming directly out of use or postuse storage destined for disposal or collection, which encompasses a

62 CGIs destined for DNA methylation show reduced protective H3K

63 , FOXO1 was expressed in a fraction of cells destined for DZ reentry.

64 hough this technique can save eyes otherwise destined for enucleation, ocular salvage may be accompan

65 binds to a misfolded nonglycosylated protein destined for ERAD, but not to the properly folded wild-t

66 ugh most circulating iron in blood plasma is destined for erythropoiesis, the mechanisms by which ery

67 ectly or indirectly with the cargo molecules destined for exit.

68 process, and also acidification of vesicles destined for exocytosis.

69 Proteins destined for export are synthesized in the endoplasmic r

70 that are silent in embryonic stem cells, but destined for expression during differentiation, includes

71 spent nuclear fuel (SNF) around the world is destined for final disposal in deep-mined geological rep

72 rished children and for identifying children destined for further growth shortfalls.

73 Metabolic resources normally destined for growth and development are redirected towar

74 Their presence in food destined for human consumption and in air samples has be

75 These shellfish, when destined for human consumption, undergo a depuration ste

76 an important potential contaminant in honey destined for human consumption.

77 eostasis and the quality of poultry products destined for human consumption.

78 Proteins destined for import into the nucleus contain nuclear loc

79 ve been employed for the preparation of MIPs destined for in vitro and in vivo targeting and bioimagi

80 ng of clathrin and adaptors around receptors destined for internalization.

81 CRgammadelta(+) T cells in the fetal thymus, destined for intraepithelial locations.

82 significant differences between individuals destined for joint replacement versus controls at region

83 The method was applied to biosolids destined for land application.

84 as not filled by the later-generated neurons destined for layer II, indicating that there is no subse

85 y endosomal sorting of EGFR between pathways destined for lysosomal degradation and recycling.

86 R escape of a misfolded proinsulin aggregate destined for lysosomal degradation via ER-phagy.

87 n internalized receptors and other cargo are destined for lysosomal degradation, they are ubiquitinat

88 which can engage ubiquitinylated substrates destined for lysosomal degradation.

89 questers bulk cytoplasm, or a specific cargo destined for lysosomal/vacuolar delivery.

90 s to Golgi--derived quality control carriers destined for lysosomes.

91 otein to recognize particular arginine tRNAs destined for m3C modification.

92 The proteomes of carriers destined for many organelles are ill-defined because the

93 nsure the continued formation of fatty acids destined for membrane phospholipid even though 24% of th

94 ntermediate containing intralumenal vesicles destined for membrane protein degradation in the lysosom

95 )/IUGR(mat), respectively) control-fed rats, destined for MetS, had a distinct metabolome at weaning

96 t allows them to capture membrane organelles destined for MT minus end-directed transport.

97 ntermediate progenitor cells (IPCs) that are destined for neuronal maturation in the hippocampal subg

98 d from the U.S. in 2010, of which 78-81% are destined for non-OECD countries.

99 enables characterization of waste materials destined for nuclear waste repositories as well as exten

100 In the 60 days prior to outbreak, units destined for outbreak had significantly lower HH adheren

101 referentially trafficked into acyl-CoA pools destined for phosphatidylinositol incorporation.

102 y amine and forming quaternary intermediates destined for phthalideisoquinolines and antimicrobial be

103 abundance of PHT1s in the secretory pathway destined for plasma membranes, but also provides a datab

104 tified distinct signatures that marked cells destined for positive selection versus apoptotic deletio

105 a wastewater treatment plant producing water destined for potable reuse.

106 l degradation of proteins in the cytosol and destined for presentation by MHC class I (MHC-I) are ass

107 bits the clearance of ubiquitinated proteins destined for proteasomal degradation by delaying their d

108 e cytosolic heat-induced Rsp5 substrates are destined for proteasomal degradation, whereas other Rsp5

109 n targets of SspH2-catalyzed Ub transfer are destined for proteasomal destruction.

110 ophobic substrates in the cytoplasm that are destined for proteasomal recycling.

111 lipid carrier of the oligosaccharide moiety destined for protein N-linked glycosylation.

112 During developmental remodeling, neurites destined for pruning often degenerate on-site.

113 biquitous non-coding RNAs that are typically destined for rapid debranching and degradation.

114 es that sweep into the population may not be destined for rapid fixation.

115 ect the general population, freezing of meat destined for raw or undercooked consumption is the most

116 suPAR appears to be higher in cases of FSGS destined for recurrence and merits further evaluation.

117 protein sorting with a majority of proteins destined for recycling, rather than MVB targeting.

118 port their survival, with excess capillaries destined for regression.This article has an associated '

119 Interestingly, target sites that were destined for release from Ago2 upon stress were depleted

120 agic targeting and clearance of mitochondria destined for removal.

121 g was performed through the section of bowel destined for resection, and slope of enhancement, time t

122 of at least two distinct pools of Abeta; one destined for secretion and the other being produced and

123 ns in the sorting and processing of proteins destined for secretion from eukaryotic cells.

124 Cargo proteins destined for secretion through T9SS carry a recognition

125 is and folding of newly synthesized proteins destined for secretion, such as insulin.

126 culum is a crucial step for folding proteins destined for secretion.

127 Bacterial proteins destined for self-assembly and host-cell targeting are t

128 Experimental mice destined for spaceflight and mice that remained on the g

129 carbon fixation, indicating that some carbon destined for specialized metabolism is likely fixed with

130 brane proteins for proper folding in samples destined for structural studies.

131 scle cells (SMCs) around those aortic arches destined for survival and reorganization, and identify t

132 mine into neurons for synthesis of glutamate destined for synaptic release is not strongly dependent

133 ons that eliminate IGF signaling cause axons destined for targets in the lateral bulb to shift to ect

134 , specific sorting of proteins into vesicles destined for the apical and basolateral domain is requir

135 Cargo vesicles destined for the axon recognize specialized microtubule

136 Proteins destined for the cell surface are first assessed in the

137 polysaccharides, proteoglycans, and proteins destined for the cell wall.

138 that serve as recruitment sites for proteins destined for the centrosome and cilium.

139 r findings indicate that structural proteins destined for the ciliary axoneme are attached to the out

140 icles not only for the transport of proteins destined for the ciliary membrane but also for the trans

141 n cells but only a small proportion of it is destined for the cytoplasm and subsequent translation, l

142 r cortices specify descending neural signals destined for the downstream interneurons and motoneurons

143 ding to cargo packaging into coated vesicles destined for the endolysosomal system.

144 Tail-anchored (TA) membrane proteins destined for the endoplasmic reticulum are chaperoned by

145 ately one-third of the proteome is initially destined for the eukaryotic endoplasmic reticulum or the

146 Most proteins destined for the extracellular space require disulfide b

147 (TA) proteins released from the ribosome and destined for the GET (Guided Entry of TA proteins) pathw

148 uired for the terminal maturation of neurons destined for the glomerular layer.

149 teins from endosomes into retrieval pathways destined for the Golgi apparatus and the plasma membrane

150 volution of biogenic amines in Canadian pork destined for the Japanese market.

151 en proposed that iron-sulfur [Fe-S] clusters destined for the maturation of [Fe-S] proteins can be pr

152 Proteins destined for the mitochondrial matrix are targeted to th

153 ls proliferation and migration of adult NSCs destined for the mouse olfactory bulb (OB).

154 Most sensory information destined for the neocortex is relayed through the thalam

155 Different subtypes of interneurons, destined for the olfactory bulb, are continuously genera

156 neurons in the human subventricular zone are destined for the olfactory bulb--we describe a major mig

157 of birth of different types of interneurons destined for the olfactory bulb.

158 mmals generates large numbers of new neurons destined for the olfactory bulb.

159 Regardless of whether they are destined for the outer or inner membrane, the intermembr

160 Most proteins destined for the peroxisomal matrix depend on the peroxi

161 STELLA may identify a subpopulation of cells destined for the PGC lineage, our findings reveal that i

162 whether glucose transporters (GLUTs, SGLTs) destined for the plasma membrane are active during ER tr

163 regulating the fission of transport carriers destined for the plasma membrane.

164 rtable, local factory for producing proteins destined for the secretory pathway.

165 ts cotranslational translocation of proteins destined for the secretory pathway.

166 specifically recognizes TMDs of TA proteins destined for the secretory pathway.

167 erograde and retrograde trafficking of cargo destined for the sensory cilium and this balance require

168 co-transcriptionally separate the pre-rRNAs destined for the small and large subunit.

169 riptional cleavage step that separates rRNAs destined for the small and large subunit.

170 ckness, mainly due to elimination of neurons destined for the superficial layers.

171 Collectively, our data suggest that MOSP destined for the TDE OM follows the canonical BAM pathwa

172 Proteins destined for the thylakoid lumen of chloroplasts must cr

173 ntent of different endosome-derived vesicles destined for the trans-Golgi network (TGN).

174 al vesicles (ILVs) containing cargo proteins destined for the vacuolar/lysosomal lumen.

175 TORC1 interacts with multiple cargo proteins destined for the Vid pathway and plays an important role

176 rationally design chemically modified siRNA destined for therapeutic use.

177 s the relaxosome, which nicks the DNA strand destined for transfer and couples the nicked substrate w

178 ll therapy, we strongly recommend that cells destined for transplant be monitored throughout their pr

179 of perfluoroalkyl acids (PFAAs) in biosolids destined for use in agriculture has raised concerns abou

180 tals (copper, zinc and cadmium) in biosolids destined for use in agriculture.

181 ing and standardizing MDI-albumin conjugates destined for use in clinical research.

182 ular mechanisms that supply neurotransmitter destined for vesicle filling, the endogenous transmitter

183 ch neural stem cells generate olfactory bulb-destined interneurons.

184 re highly expressed in queen- than in worker-destined late-instar larvae.

185 RNA-binding protein in the translation of ER-destined mRNAs.

186 s, whereas overexpression of CXCR4 in non-SG-destined NCCs induces them to migrate aberrantly toward

187 h fragment at the S3 site produces a nuclear-destined Notch intracellular domain (NICD).

188 plicable not only to photovoltaic or display-destined organic semiconductors but also to explaining t

189 Sorting signals for apically destined proteins are highly diverse and can be present

190 Encoding organelle-destined proteins in the nucleus allows for host control

191 sh5 (MutSgamma) complex, which stabilizes CO-destined recombination intermediates and members of the

192 cronuclear-limited sequences to macronuclear destined sequences at two of these loci.

193 S) are excised, followed by rejoining of MAC-destined sequences, while fragmentation occurs at conser

194 t preferentially binds endoplasmic reticulum-destined TA proteins and directs them to the GET pathway

195 These different excitability properties destine the two types for distinct functions, because th

196 a template, adding a short peptide tag that destines the aborted protein for destruction.

197 nglion mediated partly by early-born neurons destined to a myelinated phenotype participate in fating

198 oduced at specific developmental periods and destined to a specific neocortical layer.

199 socioemotional skills are unresolved issues destined to attract future research.

200 on-induced association with cellular cargoes destined to autophagic double membrane structures.

201 d kinase that phosphorylates protein domains destined to be extracellular.

202 search, where every established "rule" seems destined to be overturned.

203 The part of the RS domain destined to be phosphorylated at later stages of the rea

204 of the basic RS domain of ASF/SF2, which is destined to be phosphorylated, is bound to an acidic doc

205 ermanent cartilage or hypertrophic cartilage destined to be replaced by bone has not yet been possibl

206 he mammalian genome codes for messenger RNAs destined to be translated into proteins, and it is gener

207 Some effector proteins are secreted and are destined to be translocated and function inside host cel

208 teins, whereas another subset of proteins is destined to be transported across the cell wall into the

209 The daughter cell destined to become a neuron was derived from the more ap

210 tionally been immunology-based, is therefore destined to become a RM-based discipline.

211 diopulmonary resuscitation (CPR) of a person destined to become an organ donor has been associated wi

212 gen, with lower oxygen tension in the region destined to become articular cartilage and higher oxygen

213 er due to the recruitment of cells, normally destined to become cranial epidermis, into the otic doma

214 cartilage or hypertrophic cartilage that is destined to become endochondral bone.

215 cally upregulated in ventricular progenitors destined to become ependymal cells, but not in NSCs, and

216 o have earlier detection of a tumor that was destined to become large.

217 lial cells of the mouse airways and ependyma destined to become MCCs.

218 t STAT5 signals diverted thymocytes normally destined to become naive T cells into the Treg cell line

219 nd identified in regions of tendon which are destined to become rapidly mineralized around 14 weeks o

220 n the thrb (-/-) retina, retinal progenitors destined to become red cones were transfated into ultrav

221 riphosphatase, Cdc42, to the cortical region destined to become the "front" of the cell.

222 Before this time point, the epithelial layer destined to become the adult midgut is devoid of endocri

223 l differentiation in regions of the eye disc destined to become ventral head tissue.

224 high early in the colony cycle, when larvae destined to become workers are being reared, and low lat

225 n prevented the exit of cargo from the Golgi destined to both the plasma membrane and the late endoso

226 Proteins destined to circulate in the blood are first folded and

227 axon segments distal to transection that are destined to degenerate.

228 ' gestation and prior to intervention, women destined to develop a short cervix (n = 36) exhibited hi

229 tests to identify presymptomatic individuals destined to develop Alzheimer's disease (AD).

230 s before progressive decline in a population destined to develop illness.

231 rns, of which 2 clearly distinguish patients destined to develop NI from those who did not.

232 protective barrier, epithelia extrude cells destined to die by contracting a band of actin and myosi

233 onse to Ag during the inflammatory phase are destined to die during termination of the immune respons

234 -apoptotic gene Bax showed that even neurons destined to die formed qualitatively and quantitatively

235 hils as terminally differentiated leukocytes destined to die or to participate primarily in host inna

236 Extrusion occurs by cells destined to die signalling to surrounding epithelial cel

237 oding a functional B-cell receptor (BCR) are destined to die.

238 presses REST expression, and rescues neurons destined to die.

239 mediately after ischemia rescues CA1 neurons destined to die.

240 l CA1, seizures activate REST in CA3 neurons destined to die.

241 that provide acute protection but are often destined to die.

242 rons that express cleaved caspsase-3 and are destined to die.

243 t embryos, precursor cells that are normally destined to differentiate as beta cells instead take on

244 aining stem cell identity and the other cell destined to differentiate.

245 Persistent spines that were destined to disappear showed, on average, reduced PSD-95

246 urea nitrogen (BUN), could identify patients destined to experience adverse outcomes associated with

247 e of adequate discrimination between infants destined to experience poor outcomes and those not; comp

248 ng to identify more precisely those patients destined to experience relapse, which would allow more t

249 ought to develop stopping rules for patients destined to fail boceprevir-based combination therapy in

250 , suggesting that chronic-phase CML patients destined to fail imatinib have more advanced disease tha

251 90% in both cohorts excluded allografts not destined to fail within 5 years.

252 Patients destined to fare poorly can be identified early during t

253 months is the best way to identify patients destined to fare poorly, thereby allowing early clinical

254 Pre-migratory neural crest mesenchyme destined to form bone in the mandible was transplanted f

255 e, which targets undifferentiated mesenchyme destined to form bone.

256 y candidate pathways dysregulated in kidneys destined to form cysts.

257 rimordium (PLLP) a group of about 100 cells, destined to form sensory structures, that migrates from

258 ich enclose viroplasm consisting of proteins destined to form the cores of mature virions.

259 ere is extensive reorganisation of the cells destined to form the eyes, telencephalon and diencephalo

260 We show that at the cap stage, cells destined to form the follicle are still competent to for

261 rating NCCs express CXCR4 and this subset is destined to form the neural core of the sympathetic gang

262 y for specification of the prosensory domain destined to form the organ of Corti.

263 rned, and the anterior region is known to be destined to form the outflow tract and right ventricle.

264 errant migration of granule cell progenitors destined to form the posterior-most lobule causes this u

265 oximately one third of a cell's proteins are destined to function outside the cell's boundaries or wh

266 calized site of contact between the bilayers destined to fuse.

267 tomic differences between excitatory neurons destined to give rise to broad "proto-regions," and acti

268 In neurons destined to harbor latent virus (checkpoint 3), HSV hija

269 -143 and miR-145, in cervical cells of women destined to have a PTB.

270 nt health threat and their levels in seafood destined to human consumption are regulated in many coun

271 oteasome is a specialized type of proteasome destined to improve major histocompatibility complex (MH

272 , and human conflicts, dementia incidence is destined to increase in the developing world in tandem w

273 ental process in the mosquito vector and are destined to infect the mammalian liver.

274 yopherinbeta1 transport-receptor and cargoes destined to nuclear import.

275 h the aim of developing Argan trees orchards destined to oil production.

276 dymal cells continuously produce new neurons destined to olfactory bulb.

277 acture, reveals possible biomarkers of cells destined to perform poorly in patients.

278 of KLRG1(hi) CD8+ T cells, which are usually destined to perish during contraction, without inducing

279 These data indicate that GOLD36 is a protein destined to post-ER compartments and suggest that its ex

280 18 had big size and oval form so it could be destined to potato chips industry.

281 show that Neurod1-expressing RPCs, which are destined to produce amacrine and photoreceptor cells, ca

282 Nano-enabled products are ultimately destined to reach end-of-life with an important fraction

283 D1, responds well to initial therapy but is destined to relapse.

284 template DNA are segregated to the daughter destined to remain a stem cell, thus insuring lifetime g

285 that become mineralized compared to collagen destined to remain nonmineralized.

286 that the number of DCD kidney transplants is destined to rise in the UK, we believe that ATG is a val

287 wn, this is a rapidly emerging field that is destined to suggest novel antiviral therapies.

288 bed ribbon around midcell where septation is destined to take place.

289 ow distinct migration pathways of POMC cells destined to the anterior and intermediate lobes.

290 rk, regulating fission of transport carriers destined to the cell surface.

291 ed protein (GET) pathway selects TA proteins destined to the endoplasmic reticulum (ER) utilizing dis

292 lyzes the transfer of tail-anchored proteins destined to the endoplasmic reticulum from Sgt2 to the c

293 tics are the medicines of the future and are destined to transform the approaches by which the causes

294 Their target proteins are destined to transit cellular membranes during their bios

295 Proteins destined to travel this secretion pathway are targeted t

296 characterizing future cell therapy products destined to treat endothelial dysfunctions.

297 minority of ulcerative colitis (UC) patients destined to undergo neoplastic progression.

298 ean many threatened species might already be destined toward extinction.

299 ciliary architecture via regulation of cilia-destined trafficking.

300 -Golgi network (TGN) of plasma membrane (PM)-destined transport carriers.