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1 nglion mediated partly by early-born neurons destined to a myelinated phenotype participate in fating
2 ry cell production, and in its absence cells destined to a secretory phenotype instead adopt an absor
5 rmal cells derived from distinct regions are destined to acquire specific cardiac fates after undergo
10 e off antiretroviral therapy (ART) for those destined to be controllers and anticipate longer periods
13 natural populations that is deleterious and destined to be eliminated and the fraction of fixed diff
14 This may influence the choice of individuals destined to be exposed to higher than normal doses of ra
18 nd CPL in these tetracationic cyclophanes is destined to be of major importance in future development
22 d2 correctly identifies that a signal is not destined to be part of the mature protein's structure an
24 of the basic RS domain of ASF/SF2, which is destined to be phosphorylated, is bound to an acidic doc
26 osttransplant distinguish those from kidneys destined to be rejected, that is, C57BL/6 allografts int
27 ls in which loxP - flanked DNA sequences are destined to be removed from the genome by Cre-mediated r
28 ermanent cartilage or hypertrophic cartilage destined to be replaced by bone has not yet been possibl
30 formed in the central region of the myotome, destined to be synapse-rich, before axons extended and e
32 he mammalian genome codes for messenger RNAs destined to be translated into proteins, and it is gener
33 Some effector proteins are secreted and are destined to be translocated and function inside host cel
34 teins, whereas another subset of proteins is destined to be transported across the cell wall into the
35 onary modelling shows that ZTF J1813+4251 is destined to become a helium CV binary, reaching an orbit
38 richondrial cells of the fetal cartilage are destined to become an adipogenic subset of stromal cells
39 diopulmonary resuscitation (CPR) of a person destined to become an organ donor has been associated wi
41 gen, with lower oxygen tension in the region destined to become articular cartilage and higher oxygen
42 er due to the recruitment of cells, normally destined to become cranial epidermis, into the otic doma
43 showed that a subset of recombination events destined to become crossover products increased the freq
46 homeostasis, but also that JMJD proteins are destined to become drug targets in multiple diseases.
48 cally upregulated in ventricular progenitors destined to become ependymal cells, but not in NSCs, and
49 duce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentia
52 e-induced CTLs for the selection of epitopes destined to become immunotherapeutic for prostate cancer
53 or extrathymic differentiation by precursors destined to become intestinal intraepithelial T lymphocy
57 which adoptively transferred CD8(+) CTL are destined to become memory T cells is ambiguous as most s
58 kly reverts to discrete dots in those nuclei destined to become micronuclei, whereas it remains diffu
59 t STAT5 signals diverted thymocytes normally destined to become naive T cells into the Treg cell line
60 es loss of both Nf1 alleles in Schwann cells destined to become neoplastic and may be exacerbated by
61 enicity requires both a loss of NF1 in cells destined to become neoplastic as well as heterozygosity
63 n of mRNAs of these two frequency classes is destined to become overwhelming relatively early in any
64 that p27(Xic1) is highly expressed in cells destined to become primary neurones and is essential for
65 nd identified in regions of tendon which are destined to become rapidly mineralized around 14 weeks o
66 n the thrb (-/-) retina, retinal progenitors destined to become red cones were transfated into ultrav
67 e initiation of DNA replication at the locus destined to become silenced nor the passage of a replica
71 Before this time point, the epithelial layer destined to become the adult midgut is devoid of endocri
72 r in vitro labeling allows the regions of HS destined to become the antithrombin (AT)-binding sites t
73 e distal region of the optic vesicle that is destined to become the neural retina, suggesting a role
76 high early in the colony cycle, when larvae destined to become workers are being reared, and low lat
78 anagement by (1) shifting biomass production destined to bioenergy from forests to energy crops, (2)
79 n prevented the exit of cargo from the Golgi destined to both the plasma membrane and the late endoso
80 c dynein binds to regions of stacks that are destined to bud because dynein is present in budded memb
82 ngs elucidate why some, but not all, MIs are destined to CHF and help define a potential therapeutic
84 eplicate or generate daughter cells that are destined to commit to mature cells of different specific
85 he point at which spores became irreversibly destined to complete the uncoating process even if the o
88 irst endoderm cells to express Hesx1 are not destined to contribute to the future embryo, but instead
89 r, in zebrafish embryos, the domain of cells destined to contribute to the spinal cord extends all th
93 s, whether or not the activated T cells were destined to delete or survive, they were difficult to ex
94 syndecan-1 was consistently reduced in women destined to deliver growth restricted infants and those
95 AF, 17 were differentially abundant in women destined to deliver within two weeks of amniocentesis in
97 ' gestation and prior to intervention, women destined to develop a short cervix (n = 36) exhibited hi
99 olecular vasopermeability localized to sites destined to develop arthritis, augmenting its severity.
100 f older adults, at an age when those who are destined to develop dementia are still likely to be some
107 apid PSADT who were previously thought to be destined to develop progressive metastatic disease may a
109 Borrelia burgdorferi, in the joints of mice destined to develop severe arthritis (C3H) or mild disea
112 the ability to robustly identify individuals destined to develop type 1 diabetes was essential for cl
113 defect of beta-cell function in individuals destined to develop type 2 diabetes and that this defect
115 s, even though their spermatogenic cells are destined to die (bs/bs and qk/qk) or are programmed to u
116 n aggregates were accumulated in CA1 neurons destined to die 72 hr after 15 min of cerebral ischemia.
117 for Ca(2+) influx through AMPARs in neurons destined to die and implicate Ca(2+)-permeable AMPARs in
119 fection by preventing the apoptosis of cells destined to die because of growth factor deprivation.
120 protective barrier, epithelia extrude cells destined to die by contracting a band of actin and myosi
121 latory pathway determining the fate of cells destined to die by the default pathway of apoptosis.
122 TEMENT Under some conditions cells otherwise destined to die can be rescued just before death in a pr
124 onse to Ag during the inflammatory phase are destined to die during termination of the immune respons
125 d diaphorase-positive neurons which were all destined to die following administration of quinolinic a
126 -apoptotic gene Bax showed that even neurons destined to die formed qualitatively and quantitatively
127 striatal neural populations, including those destined to die in a rodent model of HD, and supports th
130 hils as terminally differentiated leukocytes destined to die or to participate primarily in host inna
133 n viable in the presence of TPA versus cells destined to die upon exposure to taxol or okadaic acid.
134 ription in promoting CED-3 activity in cells destined to die, it remains unclear whether the temporal
150 treak in living embryos, and find that cells destined to different structures follow defined pathways
151 ferating transit amplifying cells, which are destined to differentiate after a finite number of cell
152 t embryos, precursor cells that are normally destined to differentiate as beta cells instead take on
154 ome plants is the selective killing of cells destined to differentiate into an unwanted sexual organ.
155 cells producing high-affinity antibodies are destined to differentiate into memory B cells and plasma
156 ge numbers of committed progenitors that are destined to differentiate into spermatozoa throughout li
162 ups and single cells and show that cells not destined to enter the node can become resident and self-
163 ys independent of APOE.Some individuals seem destined to escape AD, even over an extended lifespan.
164 expansion potential are limited and they are destined to eventually stop proliferating after a finite
165 e foot soldiers of the immune system, solely destined to execute a set of effector functions against
167 urea nitrogen (BUN), could identify patients destined to experience adverse outcomes associated with
168 e of adequate discrimination between infants destined to experience poor outcomes and those not; comp
169 ng to identify more precisely those patients destined to experience relapse, which would allow more t
170 rly in the course of therapy, those patients destined to experience treatment failure with a melanoma
171 R1+ cells in CX3CR1(+/GFP) animals and cells destined to express CX3CR1 in CX3CR1(GFP/GFP) knockouts.
172 cus to study the developmental fate of cells destined to express prx-1 in the prx-1 mutant background
173 ought to develop stopping rules for patients destined to fail boceprevir-based combination therapy in
174 , suggesting that chronic-phase CML patients destined to fail imatinib have more advanced disease tha
177 onse" at 6 and 12 months identified patients destined to fare badly, although criteria at 18 months w
179 months is the best way to identify patients destined to fare poorly, thereby allowing early clinical
180 The E-Cbs typically resides within the DNA destined to form a macronuclear DNA molecule, but can al
183 xpression of spliced XBP1 in tubule segments destined to form cysts reduced cell proliferation and im
186 paraxial mesoderm, and in its absence cells destined to form posterior somites differentiate along a
188 rimordium (PLLP) a group of about 100 cells, destined to form sensory structures, that migrates from
190 we exchange pre-migratory neural crest cells destined to form the craniofacial dermis between them.
191 ere is extensive reorganisation of the cells destined to form the eyes, telencephalon and diencephalo
193 rating NCCs express CXCR4 and this subset is destined to form the neural core of the sympathetic gang
195 rned, and the anterior region is known to be destined to form the outflow tract and right ventricle.
196 errant migration of granule cell progenitors destined to form the posterior-most lobule causes this u
200 oximately one third of a cell's proteins are destined to function outside the cell's boundaries or wh
201 iosynostosis in mice, but the sites that are destined to fuse exhibit an unexpected depletion of CTSK
206 cific nature of the split human RL, which is destined to generate most of the neurons in the human br
207 tomic differences between excitatory neurons destined to give rise to broad "proto-regions," and acti
209 ctates the number of postmitotic progenitors destined to give rise to the hair cells and supporting c
210 the dorsolateral territory of the somite is destined to give rise to the hypaxial skeletal musculatu
216 nt health threat and their levels in seafood destined to human consumption are regulated in many coun
217 oteasome is a specialized type of proteasome destined to improve major histocompatibility complex (MH
218 , and human conflicts, dementia incidence is destined to increase in the developing world in tandem w
220 roblasts and essentially all definitive HPCs destined to initially seed the fetal liver after E9.5 ar
222 with many co-occurring contaminants is often destined to land application which raises concern regard
223 blood in response to cytokine exposure, are destined to later return to marrow, an observation that
224 turna changed the lives of people previously destined to live a life of blindness, but it has fueled
227 recursor cells arising in the lateral somite destined to migrate to and populate the limb musculature
228 he myotome, and later in myotomal precursors destined to migrate towards their final destination, for
235 re consistent with the hypothesis that SHBG, destined to participate in signaling at the cell membran
236 ompared the outcome of paired donor kidneys, destined to patients who had ESRD more than 2 years comp
238 of KLRG1(hi) CD8+ T cells, which are usually destined to perish during contraction, without inducing
239 E) 80 and E90 to block the division of cells destined to populate the superficial cortical layers, be
240 These data indicate that GOLD36 is a protein destined to post-ER compartments and suggest that its ex
242 show that Neurod1-expressing RPCs, which are destined to produce amacrine and photoreceptor cells, ca
243 ppropriate gene expression occurred in cells destined to produce either cell type and caused correspo
246 ation of the GGTase-I-encoding gene in cells destined to produce lung tumors driven by oncogenic K-Ra
247 an essential component of a genetic program destined to produce the cellular complexity of the mamma
249 esions and approximately 40% of all patients destined to progress to proteinuria are normoalbuminuric
254 disease focuses on the detection of patients destined to relapse despite appearing to be in clinical
258 template DNA are segregated to the daughter destined to remain a stem cell, thus insuring lifetime g
263 ancreatography and endoscopic ultrasound are destined to replace endoscopic retrograde cholangiopancr
267 that the number of DCD kidney transplants is destined to rise in the UK, we believe that ATG is a val
268 nge the notion that CD8(+) and CD8(-) DC are destined to selectively induce Th1 or Th2 responses, res
269 subsample of NutriQuebec, a web-based cohort destined to study temporal changes in dietary habits amo
277 ed protein (GET) pathway selects TA proteins destined to the endoplasmic reticulum (ER) utilizing dis
278 lyzes the transfer of tail-anchored proteins destined to the endoplasmic reticulum from Sgt2 to the c
280 ate that a subset of BiP-ligand complexes is destined to the vacuole and differs from those likely to
281 tics are the medicines of the future and are destined to transform the approaches by which the causes
287 ent NTP:P(i) was higher in patients who were destined to undergo a durable event-free survival compar
288 ses sufficiently below zero, the universe is destined to undergo a series of smooth transitions.
290 lly end-stage cells trapped in the liver and destined to undergo apoptotic cell death in that organ.
292 dent defenses and to trap pathogens in cells destined to undergo hypersensitive cell death, (ii) as a
294 of caspase-3 are administered to motoneurons destined to undergo PCD, decreased levels of APP protein
295 al interaction paradigm in which progenitors-destined to undergo programmed cell death-control the co
297 her hibernating myocardium is adaptive or is destined to undergo progressive irreversible injury.
298 this gene to determine if axotomized neurons destined to undergo retrograde death could be rescued.
299 ould be detected in the circulation of women destined to undergo spontaneous preterm birth, with eith
300 ells, those daughters of stem cells that are destined to withdraw from the cell cycle and terminally