1 Sudden cardiac death (SCD) in the young is
devastating.
2 ncrease in child and maternal deaths will be
devastating.
3 newborns, infection in this age group can be
devastating.
4 Premature, sudden death is
devastating.
5 Brachial plexus injuries are
devastating.
6 Bactrocera (Tetradacus) minax is a major and
devastating agricultural pest in Asian subtropical count
7 highly invasive and known as one of the most
devastating and deadly neoplasms.
8 recipitate aortic dissection or rupture with
devastating and often fatal consequences.
9 Fibrotic disorders are some of the most
devastating and poorly treated conditions in developed n
10 Oil spills can be environmentally
devastating and result in unintended economic and social
11 re efficacious treatment approaches for this
devastating and still uncurable disease.
12 Fulminant viral hepatitis (FVH) is a
devastating and unexplained condition that strikes other
13 , enteropathy, X-linked (IPEX) syndrome is a
devastating autoimmune disease caused by mutations in Fo
14 Systemic lupus erythematosus (SLE) is a
devastating autoimmune disease in which hyperactive T ce
15 stica) cultivars resistant to fire blight, a
devastating bacterial disease caused by Erwinia amylovor
16 The latest Permian mass extinction, the most
devastating biocrisis of the Phanerozoic, has been widel
17 In the
devastating blast fungus Magnaporthe oryzae(1), powerful
18 Retinitis pigmentosa is a
devastating,
blinding disorder that affects 1 in 4000 pe
19 in the gene encoding collagen VII cause the
devastating blistering disease recessive dystrophic epid
20 Patients with a
devastating brain injury and futile medical prognosis in
21 When patients with a
devastating brain injury had a futile prognosis in the E
22 Data regarding definition and prognosis of
devastating brain injury were extracted.
23 review of clinical charts of patients with a
devastating brain injury whose families were approached
24 pants were concerned about "recovery after a
devastating brain injury" (34%), and that "doctors would
25 efore prognosis in the various etiologies of
devastating brain injury, some common themes emerge.
26 included a case scenario of a patient with a
devastating brain injury.
27 have a significant impact on mortality from
devastating brain injury.
28 port for IDD in the case of a patient with a
devastating brain injury.
29 ean ash trees (Fraxinus excelsior) are being
devastated by the invasive alien fungus Hymenoscyphus fr
30 Pulmonary arterial hypertension (PAH) is a
devastating cardiovascular disorder characterized by the
31 tegrity during cerebral ischemia initiates a
devastating cascade of events that eventually leads to n
32 the first month posttransplant is a rare but
devastating cause of early allograft loss after kidney t
33 s known as the epicenter for seeding several
devastating cholera outbreaks across the globe.
34 athic pulmonary fibrosis (IPF) is a rare and
devastating chronic lung disease of unknown etiology.
35 Huanglongbing (HLB) is a
devastating citrus disease worldwide that is putatively
36 pathogen of citrus greening disease that is
devastating citrus industries worldwide.
37 The complexity of human cancer underlies its
devastating clinical consequences.
38 ve multifocal leukoencephalopathy (PML) is a
devastating CNS infection caused by JC virus (JCV), a po
39 Moreover, effective therapies to address the
devastating cognitive and behavioral symptoms are also u
40 Ischemic stroke is a
devastating complication affecting children with sickle
41 dy-mediated rejection (AMR) is a potentially
devastating complication and consistently effective trea
42 llograft thrombosis is the most frequent and
devastating complication in the early postrenal transpla
43 Endophthalmitis is a rare but potentially
devastating complication of intravitreal injection.
44 Prosthetic joint infection is a
devastating complication of knee replacement.
45 , parents should be informed on the possible
devastating complications and prompt surgical treatment
46 us infections is essential to preventing the
devastating complications induced by these viruses.
47 Stroke remains one of the most
devastating complications of transcatheter aortic valve
48 additional IOP-lowering surgery or visually
devastating complications) were analyzed.
49 additional IOP-lowering surgery or visually
devastating complications.
50 treatment is often inadequate in preventing
devastating complications.
51 Treatment options for this
devastating condition remain extremely limited.
52 Spinal cord ischemia (SCI) is a rare but
devastating condition that can occur in the perioperativ
53 Acute kidney injury (AKI) is a
devastating condition with high morbidity and mortality.
54 STATEMENT Tinnitus, a common and potentially
devastating condition, is the presence of a "phantom" so
55 on-specific prevention and treatment of this
devastating condition.
56 infantile encephalopathies with epilepsy are
devastating conditions mandating an accurate diagnosis t
57 Skeletal muscle wasting is a
devastating consequence of cancer that contributes to in
58 Diseases of the spinal cord often have
devastating consequences and imaging studies are indispe
59 ptomatic in the immunocompetent, it can have
devastating consequences in those with compromised or un
60 niae infection can result in bacteremia with
devastating consequences including heart damage.
61 Viral infections during pregnancy can have
devastating consequences on pregnancy outcomes, fetal de
62 Despite
devastating consequences to patients' quality of life, t
63 mmed process, the failure of which can bring
devastating consequences to the mother and fetus.
64 tion therapies in Africa would probably have
devastating consequences, and continued surveillance for
65 can report different values with potentially
devastating consequences, such as recommending to termin
66 Perinatal hepatic inflammation can have
devastating consequences.
67 ns occurs in a minority of individuals, with
devastating consequences.
68 alth among Americans to spread rapidly, with
devastating consequences.
69 f and other, which when impaired can lead to
devastating consequences.
70 enza strain might have potentially even more
devastating consequences.
71 gering global concern over these potentially
devastating consequences.
72 e resulted in deferred cancer surgeries with
devastating consequences.
73 2 (SARS-CoV-2) is the causative agent of the
devastating COVID-19 lung disease pandemic.
74 nt RNA virus, is responsible for the present
devastating COVID-19 pandemic.
75 Acrididae including grasshoppers and locust
devastate crops and eco-systems around the globe.
76 are also many species that persist following
devastating declines due to disease.
77 ect neural development and contribute to the
devastating developmental and neurological anomalies obs
78 EMENT Pontocerebellar Hypoplasia Type 3 is a
devastating developmental disorder associated with sever
79 Nuclear war, beyond its
devastating direct impacts, is expected to cause global
80 Necrotizing enterocolitis (NEC) is a
devastating disease affecting premature infants with int
81 increase, new treatment strategies for this
devastating disease are urgently needed.
82 Malaria is a
devastating disease caused by Plasmodium parasites, resu
83 es is a necessary step in controlling future
devastating disease emergences.
84 rtant role.IMPORTANCE African swine fever, a
devastating disease for domestic pigs and wild boar, is
85 st Meningococcus B, for prevention from this
devastating disease in infants and adolescents.
86 Fire blight is a
devastating disease of apple and pear caused by the bact
87 HB) caused by Fusarium graminearum (Fg) is a
devastating disease of crops, especially wheat and barle
88 us Magnaporthe oryzae causes blast, the most
devastating disease of cultivated rice.
89 ighly pathogenic avian influenza (HPAI) is a
devastating disease of poultry and a serious threat to p
90 Necrotizing enterocolitis (NEC) is a
devastating disease of premature infants with high morta
91 e underlying ELP1 splicing defect can rescue
devastating disease phenotypes and is therefore a viable
92 ities, the exact molecular mechanism of this
devastating disease remains obscure.
93 ch as pregnant women is essential to prevent
devastating disease such as that which was experienced w
94 cinia striiformis f. sp. tritici (Pst), is a
devastating disease that causes significant global grain
95 Many pathogens that caused
devastating disease throughout human history, such as Ye
96 Tomato spotted wilt virus (TSWV) is a
devastating disease to peanut growers in the South-easte
97 Pulmonary arterial hypertension (PAH) is a
devastating disease with poor prognosis and limited ther
98 nal chemistry to discover new drugs for this
devastating disease.
99 profoundly disrupts immune tolerance in this
devastating disease.
100 rostate cancer, providing insights into this
devastating disease.
101 STAT1-LNK signaling axis in this potentially
devastating disease.
102 ive strategies will be needed to defeat this
devastating disease.
103 in targeted control and elimination of this
devastating disease.
104 K2 might not be useful for treatment of this
devastating disease.
105 ts could provide novel therapeutics for this
devastating disease.
106 to epidermal keratinocytes and inducing this
devastating disease.
107 o develop novel therapeutics to control this
devastating disease.
108 cycle, that might benefit patients with this
devastating disease.
109 to develop new methods in dealing with this
devastating disease.
110 proving medical countermeasures against this
devastating disease.
111 s alternative therapy opportunities for this
devastating disease.
112 nt of alternative treatment options for this
devastating disease.
113 Breast cancer brain metastasis (BCBM) is a
devastating disease.
114 is no FDA-approved medication to treat this
devastating disease.
115 SFV genes which are essential to combat this
devastating disease.IMPORTANCE African swine fever virus
116 HLB), or Citrus Greening, is one of the most
devastating diseases affecting agriculture today.
117 will become standard of care for a number of
devastating diseases in the coming decade.
118 The fungus Magnaporthe oryzae causes
devastating diseases of crops, including rice and wheat,
119 ous diseases, there remain numerous globally
devastating diseases without fully protective vaccines,
120 romising therapeutic target to treat several
devastating diseases, including epilepsy.
121 ment of small-molecule therapeutics to treat
devastating diseases.
122 inue to provide critical insights into these
devastating diseases.
123 te respiratory distress syndrome (ARDS) is a
devastating disorder characterized by diffuse inflammati
124 n novel therapeutic approaches to treat this
devastating disorder.
125 e fundamental mechanistic insights into this
devastating disorder.SIGNIFICANCE STATEMENT Pontocerebel
126 Developmental epileptic encephalopathies are
devastating disorders characterized by intractable epile
127 heterogeneous group of inherited or acquired
devastating disorders that affect the energy metabolism
128 mum temperature and duration as the cause of
devastating disturbances in coral reefs, kelp forests, a
129 ctious diseases (EIDs) of plants continue to
devastate ecosystems and livelihoods worldwide.
130 Maternal mental illness can have a
devastating effect during the perinatal period, and has
131 mand for rhino horn is driving poaching with
devastating effect for the few individuals left of the f
132 Amputations in patients with diabetes have a
devastating effect on quality of life and are associated
133 Aging has a profound and
devastating effect on the brain.
134 Finally, the report discusses the
devastating effect the animal rights movement and advers
135 The
devastating effects and incurable nature of hereditary a
136 iculata and Calonectria henricotiae, has had
devastating effects in gardens since its first appearanc
137 ation of damaged metabolites likely triggers
devastating effects in tissues such as the brain and the
138 These disorders have
devastating effects in young children, and current thera
139 digenous communities best mitigate potential
devastating effects of COVID-19?
140 reby decreasing streamflow, with potentially
devastating effects on aquatic ecosystems.
141 Despite its
devastating effects, very little is known about how ZIKV
142 so causes sporadic pandemics, which can have
devastating effects.
143 eribacter taxon have produced pathogens with
devastating effects.
144 ting of terrestrial ecosystems following the
devastating end-Permian mass extinction.
145 l health emergency that has the potential to
devastate entire national economies as effective vaccine
146 se, which has marked European history with a
devastating epidemic at the end of the 15(th) century.
147 , with over 28,000 reported infections; this
devastating epidemic emphasized the need to understand t
148 trials in the midst of a rapidly spreading,
devastating epidemic for which there was no effective tr
149 l role in the prevention and control of this
devastating epidemic.
150 plague pandemic, caused by Yersinia pestis,
devastated Europe and the nearby regions between the 14(
151 Arguably, the most
devastating example of endocrine disruption occurred in
152 Homelessness is a
devastating experience for children and their families.
153 lub Impact may not be considered as the most
devastating extinction event for the community.
154 ls tens of thousands of Americans each year,
devastates families and entire communities, and cripples
155 nitive impairment, but might also experience
devastating features, such as memory loss, seizures and
156 management strategies for this economically
devastating fish-pathogenic oomycete A. invadans.
157 sequence, abnormal pre-mRNA splicing can be
devastating for the encoded protein, inducing a frameshi
158 pregnancy or within 6 weeks of childbirth is
devastating for the mother and her family, yet data rega
159 POI is particularly
devastating for young girls reaching puberty, because it
160 Glioblastoma is a
devastating form of brain cancer.
161 Temporal lobe epilepsy (TLE) is a common and
devastating form of human epilepsy that lacks preventive
162 Intracerebral hemorrhage (ICH) is a
devastating form of stroke affecting millions of people
163 ia graminis Pers. f. sp. tritici (Pgt), is a
devastating fungal disease threatening global wheat prod
164 tritici (Pgt), is a
devastating fungal disease threatening global wheat prod
165 Thanatephorus cucumeris) is one of the most
devastating fungal diseases which cause severe loss to r
166 Necrotizing enterocolitis (NEC) is a
devastating gastrointestinal disease of incompletely und
167 Necrotizing enterocolitis (NEC) is a
devastating gastrointestinal emergency of neonates.
168 may explain the evolutionary persistence of
devastating genetic diseases such as Huntington's diseas
169 rome coronavirus 2 (SARS-CoV-2) pandemic has
devastated global public health systems and economies, w
170 pink bollworm (Pectinophora gossypiella), a
devastating global cotton pest.
171 omising antifungal drug lead to help address
devastating global fungal pathogens such as C. auris.
172 d pandemic influenza outbreaks, which pose a
devastating global health concern.
173 ID-19) pandemic caused by SARS-CoV-2 has had
devastating global impacts and will continue to have dra
174 COVID19 is a
devastating global pandemic with epicenters in China, It
175 Streptococcus pneumoniae is a
devastating global pathogen.
176 e disorder (AUD) is a chronic condition with
devastating health and socioeconomic effects.
177 e editing for novel plant resistance against
devastating HLB.
178 eted therapeutic strategies for treating the
devastating human cancers associated with this new tumor
179 on inherited gene variants, plays a role in
devastating human conditions such as mitochondrial neuro
180 Smallpox, one of the most
devastating human diseases, killed between 300 million a
181 nto the pathogenesis and penetrance of these
devastating human diseases.
182 ensitive, deployable tests to diagnose these
devastating human diseases.
183 transferase, and amidotransferase, result in
devastating human metabolic disorders.
184 ling them to propagate efficiently and cause
devastating human pandemics.
185 Alcohol use disorder (AUD) is a
devastating illness defined by periods of heavy drinking
186 Schizophrenia is a
devastating illness that affects over 2 million people i
187 In response to
devastating illness, patients and families are frequentl
188 ated disease, COVID-19, has demonstrated the
devastating impact of a novel, infectious pathogen on a
189 gs may be one way to assist in combating the
devastating impact of ASFV.
190 novel intervention strategies to combat the
devastating impact of malaria.
191 As the world attempts to cope with the
devastating impact of the COVID-19 pandemic, researchers
192 Invasive fungal infections have a
devastating impact on human health worldwide, killing ~1
193 This pathogen has had a
devastating impact on larch plantations in the United Ki
194 and decreased water availability, can have a
devastating impact on plant growth and productivity, pot
195 COVID-19 has had a
devastating impact on the care of cancer patients.
196 fungal species are plant pathogens and have
devastating impacts on agriculture.
197 he recent African swine fever epidemic, with
devastating impacts on economy.
198 Marine heatwaves (MHWs) can cause
devastating impacts to marine life.
199 Considering the
devastating implications of nitrogen cycle disruption, t
200 ic meningitis worldwide and are particularly
devastating in the neonatal population, where they are a
201 Spinal muscular atrophy (SMA) is a
devastating infantile genetic disorder caused by the los
202 Tuberculous meningitis (TBM) is a
devastating infection of the central nervous system lack
203 Necrotizing fasciitis and myositis are
devastating infections characterized by high mortality.
204 e been utilized in attempts to control these
devastating infections, such as combinations of various
205 tists are pathogens leading to a spectrum of
devastating infectious diseases.
206 The
devastating inherited disease cystic fibrosis (CF) is ca
207 Introduced mammals have
devastated island nesting seabird populations worldwide.
208 enic avian influenza (HPAI) H5N2 in the U.S.
devastated its poultry industry and resulted in over $3
209 Parkinson disease (PD) is a
devastating,
largely nonfamilial, age-related disorder c
210 rate, but standard treatments often lead to
devastating life-long side effects and recurrence is fat
211 tation (VCA) allows tissue replacement after
devastating loss but is currently limited in application
212 .IMPORTANCE Thrips-transmitted viruses cause
devastating losses to numerous food crops worldwide.
213 effect is widely documented and can lead to
devastating losses, the underlying psychological mechani
214 regeneration is essential for recovery from
devastating lung diseases.
215 roid lipofuscinoses) constitutes a family of
devastating lysosomal storage disorders that collectivel
216 Devastating macrovascular complications (cardiovascular
217 Cognitive impairment is a common and
devastating manifestation of multiple sclerosis (MS).
218 The slow, continuous,
devastating march of Alzheimer's disease continues to mo
219 ce temperature (SST) anomalies that produced
devastating marine impacts in the Northeast Pacific duri
220 Depression is a
devastating mental disorder that affects millions of peo
221 for the early intra-mammalian stage of this
devastating metazoan parasite.
222 ine has been traditionally attributed to the
devastating Mongol invasion of the early-13th century CE
223 ceroid lipofuscinoses (NCLs) are a group of
devastating monogenetic lysosomal disorders that affect
224 Strongyloidiasis can cause
devastating morbidity and death in immunosuppressed pati
225 Friedreich's ataxia (FRDA) is a
devastating,
multisystemic disorder caused by recessive
226 oencephalopathy (PML) is a rare, potentially
devastating myelin-degrading disease caused by the JC vi
227 hquakes are responsible for some of the most
devastating natural disasters(1).
228 Trypanosomiasis is a
devastating neglected tropical disease affecting livesto
229 Biliary atresia (BA) is a
devastating neonatal cholangiopathy that progresses to f
230 alent form of dementia, is a progressive and
devastating neurodegenerative condition for which there
231 Amyotrophic lateral sclerosis (ALS) is a
devastating neurodegenerative disease affecting motor ne
232 Amyotrophic lateral sclerosis (ALS) is a
devastating neurodegenerative disease for which the orig
233 cause amyotrophic lateral sclerosis (ALS), a
devastating neurodegenerative disease.
234 in aggregates that are notorious for causing
devastating neurodegenerative diseases in mammals.
235 evelopment of effective treatments for these
devastating neurodegenerative diseases.
236 Alzheimer's disease is a
devastating neurodegenerative disorder with no cure.
237 to changes induced by genetic disorders with
devastating neurodevelopmental deficiencies.
238 Rett Syndrome is a
devastating neurodevelopmental disorder resulting from m
239 NA-binding repressor protein MeCP2 cause the
devastating neurodevelopmental disorder Rett syndrome.
240 tion of adult CNS axons is abortive, causing
devastating neurologic deficits.
241 Alzheimer's disease (AD) is a
devastating neurological disorder characterized by chang
242 While generally considered for its
devastating neurological phenotype, disturbances in othe
243 Duchenne muscular dystrophy (DMD) is a
devastating neuromuscular disease that causes progressiv
244 ll head circumference) produces particularly
devastating neuropathology.
245 usceptibility to developing schizophrenia, a
devastating neuropsychiatric disease with high heritabil
246 en unexpected death of an infant (SUDI) is a
devastating occurrence for families.
247 worldwide and perhaps the most puzzling and
devastating of all human behaviors.
248 r life, and eating disorders often result in
devastating or life-threatening conditions.
249 African meningitis belt were susceptible to
devastating outbreaks, largely attributed to serogroup A
250 currence rates after kidney transplant, with
devastating outcomes.
251 Malaria, the world's most
devastating parasitic disease, is transmitted between hu
252 ndromes in squash (Cucurbita moschata), is a
devastating pathogen worldwide.
253 Plant-parasitic nematodes are
devastating pathogens of many important agricultural cro
254 potential therapeutic target to tackle this
devastating pathology.
255 of disability worldwide, and brain injuries
devastate patients and their families, but currently no
256 Rhabdomyosarcoma (RMS) is a
devastating pediatric sarcoma.
257 Serious fungal infections continue to
devastate people living with HIV and remain a leading ca
258 Especially
devastating periods of coral loss frequently occur durin
259 the United States, some populations of this
devastating pest have rapidly evolved practical resistan
260 his sacchari Zehntner), a relatively new and
devastating pest of sorghum in the United States.
261 erapies to control citrus greening and other
devastating plant diseases caused by fastidious pathogen
262 infection-related development by a globally
devastating plant pathogenic fungus and to determine how
263 ld represent a therapeutic approach for this
devastating progeroid syndrome.
264 Pulmonary Fibrosis (IPF) is a disease with a
devastating prognosis characterized by unrelenting lung
265 le: Idiopathic pulmonary fibrosis (IPF) is a
devastating progressive disease with limited therapeutic
266 Alcohol use disorder (AUD) persists as a
devastating public health problem; widely effective phar
267 tensified to a Category 5 storm within 24 h,
devastating Puerto Rico.
268 Chordoma is a
devastating rare cancer that affects one in a million pe
269 y and thus likely contributes to many of the
devastating sequelae of chronic pain, including the poor
270 s in lactate are a key feature of this often
devastating severe mental illness.
271 Decades of overexploitation have
devastated shark populations, leaving considerable doubt
272 In a few
devastating short months in 2020, the coronavirus diseas
273 Ischemia reperfusion (IR) injury results in
devastating skeletal muscle fibrosis.
274 The biology of harlequin ichthyosis (HI), a
devastating skin disorder caused by loss-of-function mut
275 ene therapy is a promising approach to treat
devastating skin fragility diseases.
276 lly changed the structure of our lives, with
devastating social and economic consequences that are li
277 NCE STATEMENT Heightened aggression can have
devastating social consequences and may be associated wi
278 tal adenocarcinoma (PDAC) is one of the most
devastating solid malignancies, with only 9% of patients
279 Metastasis is the most
devastating stage of cancer progression and causes the m
280 While root diseases are among the most
devastating stresses in global crop production, our unde
281 ous deep intracerebral hemorrhage (ICH) is a
devastating subtype of stroke without specific treatment
282 lasmic large DNA virus (NCLDV) that causes a
devastating swine disease currently present in many coun
283 In addition to the
devastating symptoms of dementia, Alzheimer's disease (A
284 n low because detrimental conditions did not
devastate the entire Gulf Coastal Plain, allowing mollus
285 Adverse physiology and antibiotic exposure
devastate the intestinal microbiome in critical illness.
286 outbreaks can claim numerous lives and also
devastate the local health infrastructure, as well as th
287 rome coronavirus 2 (SARS-CoV-2) pandemic has
devastated the global economy and claimed more than 1.7
288 possibly related to a huge marine storm that
devastated the ports of Naples in 1343 (200 km north of
289 Outbreaks of this disease are
devastating the swine industry from Central Europe to Ea
290 The disease is
devastating the swine industry in Central Europe and Eas
291 the apex of an entropic hierarchy and impart
devastating therapy resistance.
292 that infiltrate tissues and organs to become
devastating tumors.
293 toma multiforme (GBM) is the most common and
devastating type of primary brain cancer.
294 s ruminants (PPR) is a highly contagious and
devastating viral disease affecting mainly sheep and goa
295 outh disease virus (FMDV) is one of the most
devastating viral pathogens of cloven-hoofed animals.
296 ssay for White Spot Syndrome Virus, the most
devastating virus impacting global shrimp aquaculture.
297 Cachexia, a
devastating wasting syndrome characterized by severe wei
298 species that produce food toxins, currently
devastates wheat production worldwide, yet few resistanc
299 Duchenne muscular dystrophy (DMD) is a
devastating X-linked disease affecting ~1 in 5000 males.
300 Infectious endophthalmitis is a
devastating,
yet rare, complication after intraocular su