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1 1 on both alpha-KG and glutarate (another C5-dicarboxylate).
2 Me2NH2)[In(ABDC)2] (ABDC, 2-aminobenzene-1,4-dicarboxylate).
3 MOF-74, DOBDC(4-) = 2,5-dihydroxybenzene-1,4-dicarboxylate).
4 dehyde and methyl carbon atoms to form a 1,2-dicarboxylate.
5 hyl spiro[cycloprop[2]ene-1,9'-fluorene]-2,3-dicarboxylate.
6 te reuptake blocker, l-trans-pyrrolidine-2,4-dicarboxylate.
7 obtained in one case with dimethyl acetylene dicarboxylate.
8 nitrogen, and 4 carboxylate of pyridine 2,4-dicarboxylate.
9 ate, but not by succinate, a nonexchangeable dicarboxylate.
10 ng buffer containing one fully (13)C-labeled dicarboxylate.
11 PA5530 gene was induced by extracellular C5-dicarboxylates.
12 onies and grew poorly on organic nitrogen or dicarboxylates.
13 ns and substrate specificity for four-carbon dicarboxylates.
14 ated that retained some ability to transport dicarboxylates.
15 2 mediate Na(+)-coupled transport of various dicarboxylates.
16 cells that shows preference for citrate over dicarboxylates.
17 a novel asymmetric alkylation of allylic gem-dicarboxylates.
18 ,5S,6R-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate) (0.3, 1.0, and 3.0 mg/kg, s.c.) dose depe
19 agonist APDC [(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate] (0.1 mum) or group III agonist l-(+)-2-am
20 1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate 1 (LY354740) bearing C4-thiotriazole subst
21 cycloaddition of dimethyl cyclobut-1-ene-1,2-dicarboxylate (1) with cyclohexene (7) afforded two phot
22 4-methyl (1R,2S,4R)-2-methylcyclohexane-1,4-dicarboxylate (+)-1, via palladium-catalyzed methoxycarb
23 these compounds are maleate (7), allene-1,3-dicarboxylate (10), cis,cis-muconate (11), trans,trans-m
24 e (4Z,10Z)-dimethyl cyclodeca-4,10-diene-1,4-dicarboxylate (10), which subsequently isomerized to pro
25 pyridine (10), dimethyl 2,2'-bipyridine-4,4'-dicarboxylate (11), 1,10-phenanthroline (12), 2,9-dimeth
27 ,6S-2-amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylate 2 (LY541850), exhibited an unexpected mGlu
28 is about 2000, releasing cyclopentanone-2,4-dicarboxylate (22) and two other precursors of this comp
29 oxylated 2E-fluoro-2,4-pentadienoate and the dicarboxylated 2E-fluoro-2-en-4-ynoate being the most po
30 syntheses of dimethyl 2,2'-bithiophene-4,4'-dicarboxylate (3), dimethyl 2,2'-bithiophene-3,4'-dicarb
31 eptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (3.0 microg/side) mimicked the effect of L
32 of a porous MOF, Zn(4)O(trans-4,4'-stilbene dicarboxylate)(3), with Br(2) results in diastereoselect
33 boxylate (3), dimethyl 2,2'-bithiophene-3,4'-dicarboxylate (4), and dimethyl 2,2'-bithiophene-3,3'-di
35 ethylspiro[bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate-7,1'-cycloprop ane] (B'), A:B', and A':B;
36 diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate (8), and i-Pr2NEt and their coupling in di
37 linkers (oxalate, 6; fumarate, 8; acetylene dicarboxylate, 9; cis,cis-muconate, 11; trans,trans-muco
38 ors (X-(CH(2))(n)-X) such as alkyl dithiols, dicarboxylate acids, and alkanethiol shells capped on na
42 binding to site IIf The decrease in matrix [dicarboxylate] allows O2 access to reduced site IIf, the
43 njugate was reduced by the OAT1-exchangeable dicarboxylates alpha-ketoglutarate, glutarate, and adipa
46 old, and concomitantly decrease the K(i) for dicarboxylate analogues of l-aspartate by up to 40-fold.
47 in conjunction with di-tert-butyl hydrazine dicarboxylate and an inorganic base provides a variety o
48 ew MOF [Yb2(BDC)3(DMF)2]H2O (BDC=benzene-1,4-dicarboxylate and DMF=N,N-dimethylformamide) under solvo
49 likely orients amino acid residues near the dicarboxylate and FAD binding site, which facilitates fo
50 col utilizes a combination of an iodobenzene dicarboxylate and iodine to functionalize a series of ac
51 de at 0.6 V, whereas diethyl 2,5-dioxahexane dicarboxylate and lithium propionate form on the Sn elec
52 + 2] cycloaddition between vinylcyclopropane dicarboxylates and 3-nitroindoles has been developed.
53 inity, disulfonic stilbene-sensitive flux of dicarboxylates and citrate across the plasma membrane by
55 DH4) contain all key residues for binding of dicarboxylates and quinones, but the enzyme showed the l
57 The transporter does interact with other dicarboxylates and tricarboxylates but with considerably
58 , Co, Ni; dobdc(4-) = 2,5-dioxidobenzene-1,4-dicarboxylate) and M(2)(m-dobdc) (m-dobdc(4-) = 4,6-diox
59 7 ([Zr6O4(OH)4 (bpdc)6], bpdc: 4,4'-biphenyl dicarboxylate) and UiO-abdc ([Zr6O4(OH)4 (abdc)6], abdc:
60 y structures of MOFs UWDM-2 (1,4-diazophenyl-dicarboxylate) and UWDM-3 (1,4-biphenyl-dicarboxylate) s
61 ghest reported affinity to date for these C4-dicarboxylates, and to succinate (K(d) = 110 nM) and fum
62 not group II [(2R,4R)-4-aminopyrrolidine-2,3-dicarboxylate] and III [L-AP 4 (L-(+)-2-amino-4-phosphon
64 ne (PC), and sphingomyelin (SM) cations with dicarboxylate anions are shown to charge-invert the posi
65 studied as receptors for the recognition of dicarboxylate anions of varying chain length in aqueous
66 ape complementarity between the host and the dicarboxylate anions, which is nicely reflected in the s
69 ajectory of S. Typhimurium implicates the C4-dicarboxylate antiporter DcuABC in early murine gut colo
70 mGluR agonists (2R,4R-4-aminopyrrolidine-2,4-dicarboxylate (APDC) and L(+)-2-amino-4-phosphonobutyric
71 3)) agonists (2R, 4R)-4-aminopyrrolidine-2,4-dicarboxylate (APDC) or (2S,2'R,3'R)-2-(2'3'-dicarboxycy
72 mGluR agonist, 2R,4R 4-aminopyrrolidine-2,4-dicarboxylate (APDC), did not alter thermal sensitivity
75 indicating that transport and utilization of dicarboxylates are important for virulence of DC3000.
76 owly in culture than wild-type bacteria when dicarboxylates are the only available carbon source.
78 ) and dimethyl 3,5-dimethyl-1-pyrazoline-3,5-dicarboxylate as a specific organocatalyst has been foun
79 new hosts against a series of alkyl and aryl dicarboxylates as well as a range of phosphoanionic spec
81 says, DcuABC and enzymes that convert the C4-dicarboxylates aspartate and malate into fumarate (AspA,
82 other transcriptional regulators involved in dicarboxylate assimilation, suggesting that MifR might i
85 complex of a 1,10-phenanthroline containing dicarboxylate axle with a 1,10-phenanthroline containing
86 benzo[24]crown-8 wheels, (3) 2,6-naphthalene dicarboxylate axles with tetra-imidazolium macrocycle wh
87 ary for transport was a four-carbon terminal dicarboxylate backbone and that productive substrate-tra
88 phiphilic ligand, 4'-tert-butyl-biphenyl-3,5-dicarboxylate (BBPDC), with Zn(NO(3))(2), Co(NO(3))(2),
89 O) as axial ligands and 2,2'-bipyridine-6,6'-dicarboxylate (bda) as the equatorial ligand, we have sy
90 of nonpolar functional groups on the benzene dicarboxylate (BDC) linker in the pillared DMOF-1 [Zn2(B
91 to the conservation of amino acids near the dicarboxylate binding sites of the two enzymes is that t
94 ults in succinate-dependent reduction of the dicarboxylate-binding site of complex II (site IIf); (b)
95 nedicarboxylate (NDC), and BTE/biphenyl-4,4'-dicarboxylate (BPDC), to give four metal-organic framewo
96 mu-O)(3)Mn(IV)(tmtacn)](2+) into the active, dicarboxylate-bridged [(tmtacn)Mn(III)(mu-O)(mu-RCOO)(2)
98 eptor unit 1 with several linear and angular dicarboxylate bridging ligands afforded hitherto unknown
99 highly stable MOFs (1 and 2) using elongated dicarboxylate bridging ligands derived from Cp*Ir(L)Cl c
101 ed using a post-assembly modification to the dicarboxylate building block, suggesting another strateg
102 As such, a small initial difference in the dicarboxylate building blocks is amplified into distinct
103 is apparent for several of the alkylaminium dicarboxylates but not for the alkylaminium monocarboxyl
104 tion of the transport and metabolism of C(4)-dicarboxylates, but they are not highly related by seque
105 ethyl]-amino]propyl]-1,3-benzodiox azole-2,2-dicarboxylate], but not after administration of beta1, b
107 ([Zr6O4(OH)4 (abdc)6], abdc: 4,4'-azobenzene dicarboxylate) by single-crystal nanoindentation, high-p
108 ous DEAD reagent bis(perfluorohexylethyl)azo dicarboxylate (C(6)F(13)(CH(2))(2)O(2)CN=NCO(2)(CH(2))(2
109 byproducts from bis(perfluorohexylpropyl)azo dicarboxylate (C(6)F(13)(CH(2))(3)O(2)CN=NCO(2)(CH(2))(3
110 reagent perfluorooctylpropyl tert-butyl azo dicarboxylate (C(8)F(17)(CH(2))(3)O(2)CN=NCO2(t)Bu, F-DE
111 rapid efflux of succinate/fumarate and other dicarboxylates capable of competitively binding to site
114 such as overexpression of the mitochondrial dicarboxylate carrier result in increased ROS formation
117 ecedented selectivity for fum(2-) over other dicarboxylate competitors, including its cis isomer male
119 ues, Arg-349 and Asp-373, of the renal Na(+)/dicarboxylate cotransporter (NaDC-1) have been shown in
122 SLC13A3 encodes the plasma membrane Na(+) /dicarboxylate cotransporter 3, which imports inside the
126 ithin the substrate access pore of the Na(+)/dicarboxylate cotransporter, either in a transmembrane h
127 uctural similarity to the members of the Na+-dicarboxylate cotransporter/Na+ -sulfate cotransporter (
129 aureus is a homologue of the mammalian Na(+)/dicarboxylate cotransporters (NaDC1) from the solute car
137 pane rings in 2'-aryl-1,1'-bicyclopropyl-2,2-dicarboxylates (D-A bicyclopropyl, ABCDs) in the presenc
138 units and a mixture of 2,2'-bipyridine-5,5'-dicarboxylate (dcbpy) and 1,4-benzenediacrylate (pdac) l
139 hoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate (DDB) analogues were designed and synthesi
140 gene encodes 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase (HMPDdc), an enzyme involved
141 nsporter function by L-trans-pyrrolidine 2,4-dicarboxylate decreased the rate of glutamate uptake but
142 8 [(-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate] decreased nicotine, but not food, self-ad
143 carboxylates and 1.1 to 2.2 for alkylaminium dicarboxylates, dependent on the molecular functionality
144 -anisylformamidinate), linked by unsaturated dicarboxylate dianions of various lengths have been prep
148 phthalates and di(isononyl) cyclohexane-1,2-dicarboxylate (DINCH) in 656 urine samples collected fro
150 rate levels, we hypothesize that by allowing dicarboxylate efflux from the matrix, PTP opening during
153 ydrogenation of dibenzyl 5-dipyrroketone-2,9-dicarboxylates followed by decarboxylative iodination af
154 ann reaction of 2-naphthols with acetone-1,3-dicarboxylates, followed by an intramolecular Friedel-Cr
155 legans may lead to decreased availability of dicarboxylates for cellular production of metabolic ener
156 feature a new preparation of cis-cyclobutane dicarboxylates from commercially available coumalate sta
157 Thus, SdcS facilitates the transport of the dicarboxylates fumarate, malate, and succinate across th
159 BDC) (H2DHBDC(2-) = 2,5-dihydroxybenzene-1,4-dicarboxylate) function as selective sensors for ammonia
160 selectivity follows: phenolates >/= aromatic dicarboxylates > aromatic monocarboxylates > benzenesulf
161 where TTh-CO2 = 2,2':5',2''-terthienyl-5,5''-dicarboxylate, has also been prepared and employed in th
163 des olefins along with unsaturated mono- and dicarboxylates in distributions with adjustable widths.
164 ntributes to favorable binding constants for dicarboxylates in water, as well as a high degree of sel
165 ,5S,6R-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate) in adult, but not prepubertal, mice born
167 da(2-) being [2,2':6',2''-terpyridine]-6,6''-dicarboxylate, including complex [Ru(IV)(OH)(tda-kappa-N
168 agonist APDC [(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate] induced a concentration-dependent decreas
169 In Staphylococcus aureus, the transport of dicarboxylates is mediated in part by the Na+-linked car
171 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate) is characterized for the removal of CO2 f
172 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate), is shown to undergo a topotactic oxidati
173 I)(bda)(isoq)2] (bda is 2,2'-bipyridine-6,6'-dicarboxylate; isoq is isoquinoline) exists as the open-
176 molecular clip 6 and three different linear dicarboxylates led to the formation of neutral molecular
178 -bipyridine, ppy = 2-phenylpyridine) derived dicarboxylate ligands (DBB-Ir) and then loaded with Well
179 d 2) built from [Ir(ppy)(2)(bpy)](+)-derived dicarboxylate ligands (L(1) and L(2)) and Zr(6)(mu(3)-O)
180 than those of the analogous polyunsaturated dicarboxylate linked compounds and reveal at least two s
182 nic framework (MOF) based on a BINAP-derived dicarboxylate linker, BINAP-MOF, was synthesized and pos
183 nstructed from only bipyridyl-functionalized dicarboxylate linker, both mBPV- and mPT-MOF were built
184 th four methyl groups decorating the benzene dicarboxylate linker, leads to a smooth transition from
186 demonstrated using the 2,2'-bipyridine-5,5'-dicarboxylate linker; it is energetically prohibitive fo
187 chemically unsaturated and fully conjugated dicarboxylate linkers (oxalate, 6; fumarate, 8; acetylen
190 tu ligand exchange with progressively longer dicarboxylate linkers is performed on single crystalline
192 I), were prepared using purely BINAP-derived dicarboxylate linkers or by mixing BINAP-derived linkers
197 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY354740), a potent and pharmacologically
198 (-)-4-Amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate (LY389795, (-)-3) is a highly potent and s
200 te citramalyl-CoA, an intermediate in the C5-dicarboxylate metabolic pathway that includes itaconate,
203 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate; mmen = N,N'-dimethylethylenediamine) was
204 ive Ru-bda type (bda is 2,2'-bipyridine-6,6'-dicarboxylate) molecular OER catalysts are proposed to o
205 sotope shifts implies that a wide variety of dicarboxylate monanions are asymmetric, present as a rap
206 (13)C NMR chemical shifts of cyclohexene-1,2-dicarboxylate monoanion in chloroform-d and on the (19)F
207 he hydrogen bond in hydrogen cyclohexene-1,2-dicarboxylate monoanion was determined in chloroform usi
208 ers have been described to participate in C4-dicarboxylate movement across biological membranes, but
209 thynyl-6-phenyl-1,4(+/-)dihydropyridine-3 ,5-dicarboxylate (MRS1191), by the phospholipase C inhibito
213 (4-vinylpyridine)2 (bda=2,2'-bipyridine-6,6'-dicarboxylate) on planar electrodes results in films con
215 ixtures (> or = 81% product) of the reactive dicarboxylate or monocarboxylate intermediates, 2 or 2-h
216 ly, the GT inhibitor l-trans-pyrrolidine-2-4-dicarboxylate (PDC) potentiated, whereas the positive GT
217 es the reversible hydrolysis of 2-pyrone-4,6-dicarboxylate (PDC) to 4-oxalomesaconate and 4-carboxy-2
218 with 100-500 microM L-trans-pyrrolidine-2,4-dicarboxylate (PDC), an inhibitor of glutamate re-uptake
220 trate (methyl propiolate, dimethyl acetylene dicarboxylate, phenyl acetylene, ethyl 2,3-butadienoate)
221 t energy absorptions are Mo(2)(4+) delta --> dicarboxylate pi metal-to-ligand charge transfer transit
224 neogenesis using deaminated amino acids with dicarboxylate products of peroxisomal lipid beta-oxidati
225 xanthenone fluorescent scaffold coupled to a dicarboxylate pseudocrown ether receptor to achieve sele
227 nd radicals generated from phenyliodine(III) dicarboxylate reagents and exhibits excellent functional
228 tamate analogue PDC (L-trans-pyrrolidine-2,4-dicarboxylate), reduced the current by approximately 88%
233 enyl-dicarboxylate) and UWDM-3 (1,4-biphenyl-dicarboxylate) show that both frameworks are large enoug
237 ane axle component facilitates the complexed dicarboxylate species to be sensed via a fluorescence re
239 including the SdhE assembly factor and bound dicarboxylates, stimulate covalent flavinylation by preo
243 I) lyotropic gyroid phase formed by a gemini dicarboxylate surfactant self-assembly using a combinati
246 ion of self-assembly in the Fe-biphenyl-4,4'-dicarboxylate system, demonstrating that coordination mo
248 portantly, we also identify a small molecule dicarboxylate that acts as an essential cofactor in this
249 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate) that feature step-shaped CO2 adsorption i
250 udied using a structurally similar series of dicarboxylated thiacyanine dyes that bind to the oxide s
251 on strategy, the [3]rotaxane host recognises dicarboxylates through the formation of 1:1 stoichiometr
252 boxylation of 3-hydroxy-2-methylpyridine-4,5-dicarboxylate to 3-hydroxy-2-methylpyridine-5-carboxylat
253 contribution of the polyolefinic alpha,omega-dicarboxylate to the molecular orbital undergoing oxidat
254 4'-(4-benzoate)-(2,2',2''-terpyridine)-5,5''-dicarboxylate (TPY) before being coordinated with iron c
256 mbrane transporters, proteins involved in C4-dicarboxylate transport and utilization, enzymes for bio
257 Our results reveal a new function in C4-dicarboxylate transport by members of the poorly charact
260 d transporters from the tellurite-resistance/dicarboxylate transporter (TDT) family or the Na(+) coup
261 The absence of the Arabidopsis tonoplast Dicarboxylate Transporter (tDT) in the tdt knockout muta
263 ion that increased expression of the dctA C4-dicarboxylate transporter greatly enhanced the Cit(+) ph
264 cell motility 2), SLC13A3 (sodium-dependent dicarboxylate transporter member 3), and PREX1 (phosphat
265 function of the high affinity Na(+)-coupled dicarboxylate transporter NaDC2 in C. elegans may lead t
267 ctural modeling using the x-ray structure of dicarboxylate transporter VcINDY as template and confirm
268 a crystal structure of Vibrio cholerae Na(+)-dicarboxylate transporter VcINDY, from which we generate
270 d functionally characterized a Na(+)-coupled dicarboxylate transporter, SdcS, from Staphylococcus aur
272 ion of the dctA gene, which encodes the C(4)-dicarboxylate transporter, was reduced in a gyrA751 muta
275 hila melanogaster and with the Na(+)-coupled dicarboxylate transporters NaDC1 and NaDC3 identified in
276 the differential substrate specificity among dicarboxylate transporters that underpin their diverse b
277 functionally characterized two Na(+)-coupled dicarboxylate transporters, namely ceNaDC1 and ceNaDC2,
279 on/Na(+) symporter (DASS) family translocate dicarboxylate, tricarboxylate or sulphate across cell me
280 ceptor cyclopropanes (2-arylcyclopropane-1,1-dicarboxylates) under double-catalysis conditions by tre
281 iral monomeric all-cis 5-arylpyrrolidine-2,4-dicarboxylate units were synthesized for the first time
283 as prepared from diethyl 2-nitropyrrole-3,4,-dicarboxylate via an alkylation, ammonolysis, reduction
284 on of trans-2-aroyl-3-styrylcyclopropane-1,1-dicarboxylates was investigated with different Lewis aci
287 hydroxamates derived from trans-cyclopropyl dicarboxylate were examined as potential TNF-alpha conve
291 f 4-oxo-2,4-dihydrocyclopenta[c]chromene-1,2-dicarboxylates were obtained in moderate to good yields
293 dobdc) (m-dobdc(4-) = 4,6-dioxidobenzene-1,3-dicarboxylate), which all contain a high density of coor
294 ork, we trans-hydrogenate [1-(13)C]acetylene dicarboxylate with para-enriched hydrogen using a commer
295 nding is observed for dicarboxylic acids and dicarboxylates with four-carbon chains, and the binding
297 s, Ru(bda)(L)(2) (bda = 2,2'-bipyridine-6,6'-dicarboxylate) with phosphonate or pyridyl sites for wat
298 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate) with the cyclic diamine 2-(aminomethyl)pi
299 ceptors form more endothermic complexes with dicarboxylates, with a favorable entropy of association.
300 electron spectra of nine isomeric pyridinium dicarboxylate zwitterions and three nonzwitterionic meth