ライフサイエンスコーパス: dichotomous

1 However, chaperone effects on tau are dichotomous.

2 ences in the context we examined are broadly dichotomous.

3 In analyses using dichotomous 25(OH)D levels, values greater than or equal

4 challenge the classic experience/expression dichotomous account of emotions, according to which expe

5 The dichotomous action of nicotine resulted from the up- and

6 Dichotomous activation is assessed as the fraction of re

7 ccurring human seizures, and here report two dichotomous activity patterns.

8 e (N=2547) and in independent samples with a dichotomous AG phenotype based on the Symptoms Checklist

9 Patients fell into two dichotomous age groups at the time of evaluation: six pa

10 servations suggest a different model for the dichotomous, age dependent outcome of HBV infection in h

11 Nicotine has dichotomous, age-dependent effects on microglial morphol

12 Dichotomous and categorical variables were analyzed usin

13 as used to calculate the effect size of both dichotomous and continuous data.

14 t-neighbors in high dimensions, handles both dichotomous and continuous outcomes and predictor data t

15 evelopment of a fine-root pool that was less dichotomous and more exploratory under N-limited conditi

16 y to see the world of psychiatric illness in dichotomous and opposing terms has three major sources:

17 ysis was performed by using chi(2) tests for dichotomous and ordinal variables and the t test for con

18 ancies, suggesting that this complex plays a dichotomous and poorly understood role in cancer.

19 ethod is flexible and can be applied to both dichotomous and quantitative traits and allows for the i

20 rized each study using median risk ratio for dichotomous and standardized mean difference for continu

21 T family tests when the trait of interest is dichotomous and the sample size is small.

22 Although clinical routine focuses on dichotomous and visual interpretation of amyloid PET, re

23 country-level predictors of seroconversion (dichotomous) and antibody titer (continuous), respective

24 ense heritability estimates for fatty liver (dichotomous) and fat fraction (continuous) were calculat

25 h, but also suggests complexities beyond the dichotomous approach of CLASH.

26 Trials included in the analysis reported a dichotomous assessment of overall response to therapy (r

27 Only RCTs reporting a dichotomous assessment of overall response to therapy, i

28 Both quantitative and dichotomous association analyses implicate a functional

29 These models differ in two dichotomous assumptions, constituting a 2 x 2 theoretica

30 Such dichotomous base-pairing behavior of the 5-azauracil moi

31 nisms by which MSN subtype function promotes dichotomous behavioral outcomes caused by differences in

32 shares similarities with the nodal-antinodal dichotomous behaviour observed in underdoped copper oxid

33 The dichotomous behaviour of MITF in drug response is corrob

34 But the proclivity to degrade P values into dichotomous bins corresponding to statistical significan

35 By differentiating between the two dichotomous biological activities of ANG, this strategy

36 membrane domain associated with the repeated dichotomous branching of the hyphae.

37 del is that fixation and exploration are not dichotomous, but are instead two extremes of a functiona

38 rdinal NEC score and cut points to develop a dichotomous case definition based on the highest area un

39 The ordinal NEC score and dichotomous case definition discriminated well between i

40 Ordinal NEC likelihood score, dichotomous case definition, and GA-specific probability

41 We show that, together, these dichotomous cell types fulfil the requirements necessary

42 of COL4A3 expression than to result from the dichotomous change implied by the previously proposed ec

43 A dichotomous choice for metazoan cells is between prolife

44 the four categories (kappa=0.43) and for the dichotomous classification (kappa=0.51).

45 by category (kappa=0.64 to 0.84) and for the dichotomous classification (kappa=0.63 to 0.84).

46 he four categories of breast density and for dichotomous classification as dense versus not dense.

47 of the peripheral nerves, a straightforward, dichotomous classification scheme can be used in which t

48 for 4 categories and k=0.70 to 0.87 for the dichotomous classification).

49 Its dichotomous classifications, 'functional' or 'non-functi

50 no confidence) to 100 (totally confident) on dichotomous clinical judgements of critical event risk.

51 usual care in quality of depression care and dichotomous clinical outcomes (a decrease of at least 50

52 more powerful than either the continuous or dichotomous component in isolation, or a t-test on the z

53 aks in solid-state NMR indicates very stable dichotomous conformations for both the first and second

54 Although dichotomous criteria for the metabolic syndrome (MetS) a

55 y with central reviewing according to visual dichotomous criteria.

56 index (11-15%) using PASP as a continuous or dichotomous (cutoff=33 mm Hg) variable.

57 Dichotomous data are presented as relative risk (95% CIs

58 An overall effect estimate for all dichotomous data as an odds ratio with 95% CI was calcul

59 Dichotomous data for induction of remission and continuo

60 We pooled dichotomous data to obtain relative risks of induction o

61 Dichotomous data were analyzed by random or fixed-effect

62 gA) or two (LF2 and BGLF2 IgG) antibodies on dichotomous data were identified as the most parsimoniou

63 isk difference (RD) with 95% CI was used for dichotomous data; heterogeneity was assessed with the ch

64 e considers appropriate, instead of just the dichotomous decisions of whether to 'accept or reject th

65 s was performed with 'presence of DR' as the dichotomous dependent variable and other independent cov

66 Dichotomous dermatologic depictions of heroes and villai

67 For the dichotomous diagnostic test, we selected 60 study partic

68 nscription factor, which are consistent with dichotomous differentiation of SOX2-expressing precursor

69 linkage between rare genetic variants and a dichotomous disease indicator in family pedigrees.

70 g on mendelian randomization analyses with a dichotomous disease outcome and a continuous exposure.

71 us distribution, not as a random draw from a dichotomous distribution (null vs. alternative).

72 Such a dichotomous distribution is not typically observed with

73 alyses were performed after stratifying on a dichotomous education variable.

74 These findings help explain the dichotomous effect of smoking in patients with UC and CD

75 These findings illustrate the potential for dichotomous effects of a blocker in a long pore (with mu

76 itself plays a central role in mediating the dichotomous effects of growth factor- and stress-stimula

77 ights into mechanisms that contribute to the dichotomous effects of Notch during development and tumo

78 Mechanistic investigations showed that the dichotomous effects of Nrf2 could be explained at least

79 These dichotomous effects of Stu2 are independent of its previ

80 involved in neurodegenerative diseases, have dichotomous effects on flaviviruses-with ATL2 depletion

81 These data indicate that RP105 does not have dichotomous effects on TLR4 signaling and emphasize the

82 infection by multivariate modeling with four dichotomous effects: mouse strain (A/J or C57BL/6), diet

83 We tested dichotomous end points by chi(2) test and NT-proBNP by M

84 We describe stereoselectively dichotomous enyne cycloisomerizations, entirely dependen

85 different lymphocyte subsets to produce this dichotomous eosinophilia or neutrophilia.

86 ia, the compulsion to perceive quantities as dichotomous even when dichotomization is unnecessary and

87 Dichotomous events or odds ratios (ORs) of suicide, suic

88 x proportional hazards regression model with dichotomous ever/never categorization.

89 determined from cross-product terms between dichotomous (ever/never) solvent variables and genotypes

90 For dichotomous exposures and outcomes, the typical 2-stage

91 rence estimates and that are appropriate for dichotomous exposures and outcomes.

92 of measures of additive interaction between dichotomous exposures, such as the relative excess risk

93 orphisms in IL1RL1 were found in relation to dichotomous expression of both ST2L and sST2.

94 jects were genotyped and the relationship of dichotomous expression of ST2L and sST2 to single nucleo

95 In yeast, genes exhibit dichotomous expression patterns based on their promoter

96 Here we show that microbially driven dichotomous faecal immunoglobulin-A (IgA) levels in wild

97 When using a dichotomous FFR value of 0.80, C statistic was significa

98 ed; mean values were largely consistent with dichotomous findings.

99 n alternative perspective to the traditional dichotomous framework of ongoing and evoked activity.

100 The dichotomous function of EZH2 in regulating differentiati

101 mation remain elusive because Notch displays dichotomous functional activities, promoting both prolif

102 clusion, our data support the concept that a dichotomous functional organization, as actioned by arky

103 l model that helps to explain the strikingly dichotomous functionality of MSCs in inflammation and im

104 These dichotomous functions are performed by three distinct ce

105 f SIRTs in cancer is extremely complex, with dichotomous functions depending on cell contexts.

106 n tumor suppression and promotion, and these dichotomous functions have frustrated the development of

107 Collectively, current study elucidated dichotomous functions of BTLA in GVHD to serve as a cost

108 The dichotomous functions of TGF-beta are proposed to be dic

109 e test a treatment strategy that targets the dichotomous functions of the two receptors by inhibiting

110 nts in cancer that are associated with these dichotomous functions.

111 these findings reveal a trait with markedly dichotomous functions.

112 The cutoff scores for the dichotomous GA-specific case definition were 2 or greate

113 d interleukin 8 (IL-8) were compared between dichotomous groups with low or high serum 25(OH)D concen

114 ntinuous blood pressure were associated with dichotomous hypertension.

115 endent mechanism through which gp96 controls dichotomous immune responses relevant to the therapy of

116 Understanding these dichotomous impacts of MMP14 provides novel insights int

117 Hydrogen sulfide (H(2)S) is dichotomous in nature as it is lethal at higher concentr

118 on analyses, both large and small, have been dichotomous in nature, in which phenotypes are compared

119 Medium spiny neurons (MSNs) in striatum are dichotomous in their expression of either D1 or D2 dopam

120 Dichotomous indicator for counties with at least 1 outpa

121 Dichotomous indicators for whether a zip code tabulation

122 (Liebowitz Social Anxiety Scale (LSAS)) and dichotomous indicators of response (LSAS </= 50) and rem

123 In dichotomous indices of therapeutic response, a significa

124 Dichotomous interreader reliability (kappa) for the enti

125 , linear weighted kappa = 0.90 +/- 0.06, and dichotomous kappa = 0.91 +/- 0.07).

126 Such dichotomous kinetics implicate additional rate-limiting

127 However, along with many benefits, this dichotomous lens can distort questions, and may contribu

128 s of TKI resistance have been viewed under a dichotomous lens.

129 continuous normalized variable, as well as a dichotomous LGE variable based on previously validated m

130 ic regression, (2) homogeneity tests, or (3) dichotomous logistic regression, analyzing all 7 possibl

131 unomodulatory fibroblast sub-populations and dichotomous macrophage populations.

132 FITs are invariably used in a dichotomous manner using pre-specified cut-off values.

133 and the ER is currently used clinically as a dichotomous marker.

134 The primary antimicrobial outcome was a dichotomous measure (<15 colony-forming units or >/= 15

135 over the subsequent 4 years compared with a dichotomous measure in middle-aged and older adults.

136 n was treated as a continuous, rather than a dichotomous, measure and when controlling for age and st

137 correlated across all diagnostic groups, and dichotomous measurements were in agreement in 86% of sub

138 d assessment of pathology beyond traditional dichotomous measures.

139 A dichotomous method was also developed to enable rapid de

140 trical flow distributions at bifurcations in dichotomous microvascular networks.

141 Simulated scenarios focused on continuous or dichotomous missing outcome data from randomized trials

142 These mechanisms coordinately lead to a dichotomous mitochondrial optimization, namely increased

143 A predefined dichotomous model classified tumors as "high expressor"

144 The dichotomous model of "drivers" and "passengers" in cance

145 ms that cannot be appropriately modeled by a dichotomous model; the subjects in a study may be recrui

146 ge and motor composite scores, growth, and a dichotomous mortality and morbidity index.

147 utrophils contribute to the development of a dichotomous myeloid compartment.

148 and steatohepatitis, two states with fairly dichotomous natural history.

149 The dichotomous nature of Gal-9 is evident in hepatocellular

150 The dichotomous nature of the debate (above or below) has be

151 asi-likelihood framework, which exploits the dichotomous nature of the trait and achieves computation

152 t compensated for, which may account for the dichotomous nature of this farming symbiosis.

153 es to climate change are often guided by the dichotomous needs to resolve either (i) internal plant w

154 enescence checkpoint functions may influence dichotomous Notch activities in the neoplastic context.

155 experimental approach, that these apparently dichotomous observations can simply result from a single

156 Dichotomous, or even opposing, functions have been descr

157 es in rats to determine whether and how this dichotomous organization applies to the dopamine-intact

158 at GPe exhibits several core components of a dichotomous organization as fundamental as that in stria

159 l was fitted for each individual DM, using a dichotomous outcome (1 = each DM; 0 = rest of hospital b

160 evels were examined as both a continuous and dichotomous outcome (using a threshold of 130 mg/dL).

161 Risk ratio for dichotomous outcome and standardized mean difference for

162 In contrast to the commonly used dichotomous outcome FA vs no FA, the allergy status is i

163 and (3) reported a statistically significant dichotomous outcome in the abstract.

164 sh-language trials and could not incorporate dichotomous outcome measures into the analysis.

165 different preparations of CHG and PVI on the dichotomous outcome of surgical site infection.

166 he effects of all independent variables on a dichotomous outcome recurrence in relation to time.

167 on model for pain exacerbation measured as a dichotomous outcome variable, and a mixed-effects regres

168 prenatal urinary BPA concentration with the dichotomous outcome wheeze (wheeze over the previous 6 m

169 A probabilistic model of each dichotomous outcome, derived using a stepwise Bayesian p

170 To demonstrate the application of ISM with a dichotomous outcome, we prospectively examined the assoc

171 t and term or preterm (<37 weeks) birth as a dichotomous outcome.

172 juries were modeled using SEM procedures for dichotomous outcomes and a complex sampling design.

173 M is a useful approach with which to examine dichotomous outcomes and indirect effects in complex sam

174 We pooled risk ratios of dichotomous outcomes and mean differences of continuous

175 in meta-analyses, reporting odds ratios for dichotomous outcomes and standardized mean differences f

176 e of outcome-dependent sampling not only for dichotomous outcomes but also for continuous outcomes in

177 ccumbens medium spiny neurons (MSNs) promote dichotomous outcomes in motivated behaviors.

178 these are not the primary forces behind the dichotomous outcomes observed but reveal a limited capac

179 ulated as mean differences with 95% CIs, and dichotomous outcomes were calculated as Mantel-Haenszel

180 For dichotomous outcomes, the authors discuss when the stand

181 For dichotomous outcomes, we entered the number of events an

182 table for serial monitoring of continuous or dichotomous outcomes.

183 e risks (RRs) with corresponding 95% CIs for dichotomous outcomes.

184 diators has mainly focused on continuous and dichotomous outcomes.

185 g mechanistic models of HLH pathology into a dichotomous pathogenesis driven through discrete pathway

186 Second, a superordinate, dichotomous pattern of activation/deactivation, is commo

187 rongly symptom-provoking conditions evoked a dichotomous pattern of deactivation/activation in patien

188 We observed a dichotomous pattern of PKM expression, in which postmito

189 ciated with SC were also associated with the dichotomous phenotype, DSM-IV AD.

190 providing a clearer picture than analyses of dichotomous phenotypes and environments.

191 ly using a mixed model approach to partition dichotomous phenotypes into additive risk and non-additi

192 ach was used: (1) a mixed model to partition dichotomous phenotypes into an additive component and no

193 bilistic model to predict the probability of dichotomous phenotypes.

194 Taken together, two largely dichotomous populations of LGI1 mAbs with distinct domai

195 gnitive decline that is not available from a dichotomous positive/negative categorization.

196 ch outcome, physicians and nurses provided a dichotomous prediction and rated their confidence in tha

197 obing depth (PD), clinical attachment level, dichotomous presence or absence of supragingival plaque

198 dmission serum creatinine was categorized as dichotomous (presence of CKD as <60) or as distinct cate

199 sizes >500 and a 2-by-2 factorial design or dichotomous primary outcomes were selected.

200 cytes (CTLs) is typically considered to be a dichotomous process and uncommon during chronic HIV-1 in

201 ity approach therefore identified apparently dichotomous processes characterizing the amyotrophic lat

202 bias were identified that not only manifest dichotomous protein expression but also are enriched in

203 Logistic regression analysis showed that dichotomous qualitative assessment of wall thickening (>

204 In response to a dichotomous question, 37% of parents supported testing m

205 In response to a dichotomous question, 44% of parents reported hypothetic

206 Dichotomous questions and visual analogue scales (VASs)

207 , comparisons between summary scores for the dichotomous questions between the CLE cases and non-CLE

208 tron emission tomography scan is to assign a dichotomous rating of positive or negative for the prese

209 ese findings underscore a previously unknown dichotomous regulation of ILC3s by Helicobacter species,

210 data provide a molecular explanation for the dichotomous regulatory activities of Soj, as well as ass

211 However, it displays a dichotomous requirement for initiation site selection be

212 This method predicted the dichotomous resistance outcome of whether the IC50 neutr

213 dar hypomorph is paralleled by an unexpected dichotomous response of ADAR target transcripts, i.e. ce

214 The mechanisms responsible for the dichotomous response of neonatal and adult CD161(hi) cel

215 Conclusion: There is rapid dichotomous response on (68)Ga-PSMA PET imaging to AB-de

216 at naive CD4+ T cells from DBA/1 mice have a dichotomous response to TGFbeta: enhanced RORgammat, yet

217 Critically, this dichotomous response was associated with enhanced regula

218 n by clinically relevant genetic changes but dichotomous responses to hormonal therapy, we show that

219 dels, together with longitudinal modeling of dichotomous responses.

220 thalmology trials, statistically significant dichotomous results are often fragile, meaning that a di

221 menology of photic integration and suggest a dichotomous retinohypothalamic network leading to circad

222 is proposed to identify patterns of multiple dichotomous risk factors for outcomes of interest in gen

223 Together, our data describe a dichotomous role for ATF3-mediated regulation of neutrop

224 er, our findings reveal a context-dependent, dichotomous role for NaCl in shaping Th17 cell pathogeni

225 surface and soluble TbetaRIII may regulate a dichotomous role for TbetaRIII during cancer progression

226 This study identifies a novel dichotomous role for TLR4 as a growth regulator and a mo

227 Natural killer (NK) cells play a dichotomous role in alloimmune responses because they ar

228 B cells have a dichotomous role in both the pathogenesis and recovery f

229 Autophagy serves a dichotomous role in cancer and recent advances have help

230 tratumoral parasympathetic nerves may have a dichotomous role in cancer progression and may induce Wn

231 In summary, this study shows that Pfn1 has a dichotomous role in early vs late steps of breast cancer

232 rmore, we demonstrated that KDM2B exhibits a dichotomous role in hematopoietic malignancies.

233 es particularly intriguing cells given their dichotomous role in protecting against, or accelerating,

234 Thus, autophagy plays a dichotomous role in this model of disease.

235 These observations reveal an unexpected dichotomous role of BAF60a-mediated chromatin remodeling

236 anced in the nucleus accumbens, suggesting a dichotomous role of BDNF signaling in striatal regions.

237 Marcus theory may explain the dichotomous role of exciting the donor or the acceptor o

238 Here we report a dichotomous role of megakaryocytes (MKs) in both maintai

239 were both driven by IFN-gamma, revealing the dichotomous role of this cytokine in regulating IL-12-me

240 Here, we will review in detail the dichotomous role of TLRs in tumor biology, focusing on r

241 Thus, we have investigated the potential dichotomous role of YAP in UCC response to chemotherapy

242 The TGFbeta cytokine plays dichotomous roles during tumor progression.

243 , we hypothesize that ET(A)R and ET(B)R play dichotomous roles in oral carcinogenesis and pain, such

244 MOylation-based mechanism controlling WASp's dichotomous roles in transcription may have implications

245 Here, we delve into the dichotomous roles of IL-17 in cancer and provide insight

246 The dichotomous roles of immune cell-derived exosomes toward

247 tor cells, yet how this pathway serves these dichotomous roles remains enigmatic.

248 Dichotomous root branching in Selaginella appears to be

249 , and bone metastases present [M1]) and on a dichotomous scale (M0/M1).

250 On a lesion level (dichotomous scale), the observers agreed on the number a

251 ground radiation both in analyses based on a dichotomous score and in analyses of continuous scores o

252 Two dichotomous self-reported alcohol consumption variables,

253 A dichotomous separation of hepatitis B viral DNA and HBsA

254 A dichotomous separation of hepatitis B viral DNA and hepa

255 A dichotomous society emerges with cooperators prospering

256 This dichotomous spatial organization is especially pronounce

257 This suggests that applying a dichotomous-stage diagnosis on the basis of CSF pleocyto

258 To model dichotomous states of persistent Ag exposure in the pres

259 calins and 7,6-bicycles can be obtained with dichotomous stereochemical outcomes.

260 ess type-1 and type-2 dopamine receptors are dichotomous, such that these neurons are selectively sen

261 e the view that exploration and fixation are dichotomous, suggesting instead that visual fixation is

262 Here, subnetworks are defined using serial dichotomous suppression and enforcement of flux through

263 he Pediatric Risk of Mortality III score) in dichotomous (survival and death) and trichotomous (survi

264 cterized Scl1 proteins of S. pyogenes show a dichotomous switch in ligand binding between human tissu

265 rovocative but premature, and is vitiated by dichotomous thinking, interpretive double standards, and

266 er family members rather than a qualitative, dichotomous trait and comparing probands with the health

267 on to solving the classification problem for dichotomous trait disease models, our results apply to a

268 on and rare) in a region and a continuous or dichotomous trait while easily adjusting for covariates.

269 protein-coding genes with a quantitative or dichotomous trait.

270 loci across more than 3,000 quantitative and dichotomous traits, with separate analyses for common an

271 is known only for continuous traits and for dichotomous traits.

272 -genome sequencing studies of continuous and dichotomous traits.

273 small, especially for the important case of dichotomous traits.

274 MECP2 is a dichotomous transcription regulator that either activate

275 Our findings show that HDAC3 is a dichotomous transcriptional activator and repressor, wit

276 g an AhR agonist-specific mutually exclusive dichotomous transcriptional response.

277 sease control rate (DCR; CR/PR/SD v PD), and dichotomous tumor response (DiTR; CR/PR v others) metric

278 elated with survival, the impact of a single dichotomous value to predict outcomes was limited.

279 ous basis given limited ability of a single, dichotomous value to predict outcomes.

280 able using cumulative logit regression, as a dichotomous variable (excellent/very good/good versus fa

281 outcomes, most studies have treated it as a dichotomous variable based on academic credentials.

282 oportional hazards model, incorporation of a dichotomous variable by defining hypertension as CBP >/=

283 The exposure was a time-varying dichotomous variable equal to 1 for patients who were pr

284 Similar model with V-wave change as a dichotomous variable showed that patients with a V-wave

285 e number of positive findings and deriving a dichotomous variable to approximate the top quintile ("h

286 Each single treatment agent was entered as a dichotomous variable to determine treatments associated

287 Neither emphysema score nor emphysema as a dichotomous variable was an independent predictor of out

288 For abdominal obesity, a dichotomous variable was created: 1) eutrophic/lost weig

289 action between use of sunitinib and age as a dichotomous variable was highly significant (P = 0.003).

290 Fibrosis as a dichotomous variable was independently associated with t

291 Lung diseases were also assessed as dichotomous variables (zero vs nonzero scores).

292 (RR) and 95% confidence intervals (CIs) for dichotomous variables and as standardized mean differenc

293 Dichotomous variables were analyzed by chi2 test and con

294 e of past and acute herpesvirus infection as dichotomous variables.

295 ontinuous distributions that are analyzed as dichotomous variables.

296 ent between 1.5 T and 3.0 T on compositional dichotomous variables.

297 A dichotomous vascular construct was created from the pres

298 This dichotomous view is buoyed by the high expression of alp

299 constructs, and critically examines both the dichotomous view of learning as well as the claim that l

300 At the same time, a dichotomous view that separates noncognitive, unconsciou