ライフサイエンスコーパス: diene

1 unsaturated hydrocarbons (alkynes, alkenes, dienes).

2 tilized as a masking group for the sensitive diene.

3 uenced by the s-cis or s-trans nature of the diene.

4 ediated coupling of (Me(3) Si)CHN(2) and the diene.

5 ction of a versatile cyclic carbamate siloxy diene.

6 quinone dienophile and a silyl ketene acetal diene.

7 chenck-ene reaction, and photooxidation of a diene.

8 er product 3 with a zero-order dependence on diene.

9 ar terminal 1,3-dienes and 2-substituted 1,3-dienes.

10 d is promoted by a hydrazine reagent and 1,3-dienes.

11 tif and the formation of decorated (E,Z)-1,3-dienes.

12 with 2-substituted or 2,3-disubstituted 1,3-dienes.

13 he intermolecular coupling of amines and 1,3-dienes.

14 addition of aliphatic amines to acyclic 1,3-dienes.

15 y measured following formation of conjugated dienes.

16 -Diels-Alder cycloaddition of aldehydes with dienes.

17 oadditions of vinylidene equivalents and 1,3-dienes.

18 quaternary carbon by using 1,2-disubstituted dienes.

19 ynthesized and found to be unreactive toward dienes.

20 ntioselective hydroamination of branched 1,3-dienes.

21 n be achieved by employing 1,2-disubstituted dienes.

22 alyze [4 + 1]-cycloaddition reactions of 1,3-dienes.

23 DFT calculations indicate that the initial diene 1,2-borocupration forms a (3) eta-allylic copper a

24 trated that 2-dodecyl-6-methoxycyclohexa-2,5-diene- 1,4-dione (DMDD) remarkably inhibited the growth

25 1,2,3,4,8,9,10,11-octaazacyclotetradeca-2,9-diene-1,4,8,11-tetraido (OIM) ligand.

26 compound, 2-Dodecyl-6-methoxycyclohexa-2, 5-diene-1,4-dione (DMDD), which was extracted from the roo

27 e 3,5- dimethoxy-2-(methylthio)cyclohexa-2,5-diene-1,4-dione, and the blue compound was determined to

28 5-methoxy-2,3- bis(methylthio)cyclohexa-2,5-diene-1,4-dione.

29 acyanobutadiene (TCBD, A') and cyclohexa-2,5-diene-1,4-diylidene-expanded TCBD (A") as the acceptor u

30 tracyanobutadiene (TCBD) and a cyclohexa-2,5-diene-1,4-diylidene-expanded TCBD unit results in strong

31 The TCBD-linked and cyclohexa-2,5-diene-1,4-diylidene-expanded TCBD-linked phenothiazines

32 e (1S,6R)-5-ethyl-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylic acid (4) into compound 3, the latter

33 nes, 3 H-spiro[benzofuran-2,1'-cyclohexa[2,5]diene]-3,4'-diones, and biaryl compounds.

34 mmetric diol 3 and Heck cyclization of bromo-diene 5 to form the chromane core.

35 As reaction products, 2,4-diene-6-ols or divinyl ketones were obtained.

36 assistance of reactions using deuterated 1,3-dienes, a proposed mechanism is provided.

37 +4] cycloaddition of the pyrrole system with dienes, a wide variation of both reaction partners is po

38 eaction using a carbamate-substituted siloxy diene accompanied by a spontaneous intramolecular substi

39 Also, it was found that impurities in the diene affected the rate of the reaction.

40 by formation of an intermediate 1-amino-1,3-diene, affording highly functionalized cyclohexenes with

41 Subsequent steps provided the common diene alcohol, which underwent BF3.Et2O-mediated Et3SiH

42 f various biochemical compounds, from simple diene-alcohols have been carried out in a cascade fashio

43 of allylic amines from readily available 1,3-dienes, alkyl iodides, and amines.

44 1-(1-Benzyl-1H-tetrazol-5-yl)propa-1,2-diene and 3-methyl-, 3-ethyl- and 3-benzyl derivatives u

45 nriched organics was also demonstrated for a diene and a trisubstituted cyclohexene.

46 s-Alder reaction was investigated, including diene and dienophile substitution patterns and dienophil

47 emonstrate the interactions of MaDA with the diene and dienophile to catalyse the [4+2] cycloaddition

48 precursor and zeroth order behavior in both diene and N(2) pressure were measured.

49 on reaction between a halogenated conjugated diene and nitrogen-containing nucleophiles.

50 onverted (Z,E)-FPP to (6R,7S)-himachala-9,11-diene and other sesquiterpenes observed in beetle extrac

51 >95:5) for a variety of linear terminal 1,3-dienes and 2-substituted 1,3-dienes.

52 erent substrates, including 17 prochiral 1,3-dienes and 3 acrylates, this hetero-dimerization reactio

53 equential addition to internally substituted dienes and a wide range of aldehydes and activated keton

54 th range of cyclic, heterocyclic, and acyclc dienes and also the reaction of cyclopentadiene with mal

55 ntial addition to internally substituted 1,3-dienes and an electrophilic cyanating reagent with high

56 multisubstituted indenes from alkyl aryl-1,3-dienes and aromatic aldehydes through tandem addition/4p

57 of second and third dehydrogenations to form dienes and aromatics such as benzene.

58 s are reactive through cycloadditions toward dienes and azides, promoted by the electron-withdrawing

59 able of bimolecular assembly of 2-siloxy-1,4-dienes and can be used to access beta,gamma-unsaturated

60 , and the lowest peroxide values, conjugated dienes and conjugated trienes.

61 xhibits a substrate promiscuity towards both dienes and dienophiles, which enables the expedient synt

62 s protocol is compatible with both mono- and dienes and exhibits a good functional group tolerance an

63 an effective base for the metalation of 1,4-dienes and isomerization of alkenes.

64 ereoselective manner with electron-deficient dienes and olefins.

65 products comprising hydroperoxides, hydroxy-dienes and other alcohols, epoxides, aldehydes and keto-

66 In the control oil, the conjugated dienes and the peroxide value observed were respectively

67 rgon purging, pH variation) using Conjugated Dienes and Thiobarbituric acid reactive substances assay

68 ring the peroxide value, acidity, conjugated dienes and trienes.

69 eaction between alkylidene azlactone-derived dienes and trifluoromethyl aryl ketones is reported for

70 nsaturation (or oxidation state) of the 4pi (diene) and 2pi (dienophile) pairs of reactants dictates

71 Alkynes, branched 1,3-dienes, and bicyclic alkenes were also found to be compe

72 ion of hexachlorocyclopentadiene with cyclic dienes, and both have elemental compositions of C18H12Cl

73 substituted styrenes, substituted conjugated dienes, and cyclic alkenes.

74 s, heterocyclic compounds, stereodefined 1,3-dienes, and ligands for catalytic asymmetric synthesis.

75 tive 1,2-hydroborations of 2-substituted 1,3-dienes are best accomplished using a catalyst prepared v

76 Additions of acids to 1,3-dienes are conventionally understood as involving discre

77 PhS- and PhNH-functionalized dienes are copolymerized efficiently with butadiene to s

78 Conjugated dienes are coupled to nucleophiles to demonstrate the fe

79 soprene and other internally monosubstituted dienes are effective inputs, with the reaction proceedin

80 vity is achieved in 37 examples, where (E,E)-dienes are exclusively formed.

81 Reactions of keteniminium cations with 1,3-dienes are influenced by the s-cis or s-trans nature of

82 s, beta-indole-substituted diazo esters, and dienes are obtained with good to high yields and selecti

83 N)Ni]-catalyzed hydroalkylations of branched dienes are reported.

84 1,3-Dienes are ubiquitous and easily synthesized starting ma

85 the two pathways leading to cyclobutenes or dienes are very close in energy.

86 activity analyses identified the lactone and diene as moieties conferring anticancer activity, thus i

87 s were incompatible with the dihydropyridine diene as they induced its decomposition.

88 lation of ketones using widely available 1,3-dienes as allylmetal surrogates.

89 Cis,trans-conjugated dienes associated with hydroperoxides, as well as monoep

90 ty in the ring-closing metathesis of various dienes at elevated substrate concentration up to 25 mM u

91 exes, as well as the [(R,R)-((iPr) DuPhos)Co(diene)][BAr(F) (4) ] derivatives, proved to be highly ac

92 xes, [(R,R)-((iPr) DuPhos)Co(eta(2) ,eta(2) -diene)][BAr(F) (4) ].

93 le synthesis of a bench-stable cyclohexa-1,4-diene-based surrogate of gaseous hydrogen iodide are des

94 thylene, yielding 1,1,4,4-tetracyanobuta-1,3-dienes-based push-pull chromophores.

95 displays high diastereoselectivity when the diene bears an additional alkene substituent but not an

96 y 1,4-addition with linear unsubstituted 1,3-dienes, but, surprisingly, selective 1,2-additions with

97 The oxidative cyclization of 1,5-dienes by metal-oxo species is a powerful method for ste

98 ed a mutation that disrupts the amorpha-4,11-diene C-12 oxidase (CYP71AV1) enzyme, responsible for a

99 ric 2,5-disubstituted bicyclo[3.3.0]octa-2,5-dienes C2-L and CS-L, respectively, were synthesized fro

100 s involved in the metabolism of cyclohex-1,5-diene carboxyl-CoA to acetyl-CoA were in high abundance

101 Oxidative cyclization of (2E,6E)-octa-2,6-diene catalyzed by OsO(4)/NMO has been studied using den

102 Conjugated dienes (CDs) were rapidly measured using a previously de

103 The resulting 1,3-diene complexes can undergo a second protonation and nuc

104 reaction with cationic eta(5)-iron carbonyl diene complexes under mild reaction conditions is demons

105 oach was performed by correlating conjugated diene concentrations measured by spectrophotometry and t

106 vice was performed by correlating conjugated diene concentrations measured by spectrophotometry and t

107 Here, we show that dienes containing an E-alkenyl-B(pinacolato) group, wide

108 al alkynes leads to the formation of skipped dienes containing trisubstituted alkenes.

109 Here, we describe a diene-containing noncanonical amino acid (ncAA) capable

110 When the diene contains an additional stereogenic center, effecti

111 , and only a small excess (1.5 equiv) of the diene coupling partner is required to achieve high yield

112 catalyst and extends to diverse tosylate and diene coupling partners.

113 ieve high yields of the desired internal E,Z-diene cross-metathesis product.

114 ducts consistent with fleeting cycloocta-1,2-diene (cyclic allene), which was fully characterized as

115 Optimization of a reductive diene cyclization led to the development of an intermole

116 H-Cyclohepta[ b]pyridin-9-one was used as a diene cycloaddition partner to construct [3.2.2] bicycle

117 onformational change of dibenzocycloocta-1,5-diene (DBCOD), a rigid-flexible-rigid organic moiety, fr

118 cycloadditions of indoles with 1,2-diaza-1,3-dienes (DDs) is reported.

119 y treatment of resorcinols and 1,2-diaza-1,3-dienes (DDs) under acidic conditions.

120 eta-amidothioamides (ATAs) and 1,2-diaza-1,3-dienes (DDs).

121 ntermediates providing access to thiophenes, dienes, dendralenes, and vic-quarternary carbon centers.

122 of pinacolborane (HBPin) to a variety of 1,3-dienes depending on the ligands chosen.

123 With TiCl4, they furnished E,E-1,3-diene derivatives stereoselectively via ring opening fol

124 l or allyl group to the epoxide produced the diene derivatives that were subjected to the ring closin

125 s a wide range of reactions as a Diels-Alder diene, dienophile, and [2 + 2] addend.

126 Analysis of the diene-dienophile interactions reveal that the reactivity

127 Diels-Alder cyclization of diverse diene-dienophile reactive pairs proceeds rapidly, in hig

128 All rely on the same starting material, the diene diol derived from phenethyl acetate by the whole-c

129 tylated hydroxyanisole (BHA)] for conjugated dienes (during a 90-day period) and for malonaldehydes (

130 , thus producing the isomeric and cyclic 1,4-diene (e.g., 12).

131 h selectivity, including for the substituted dienes (E)-1,3-pentadiene and (2E,4E)-2,4-hexadiene.

132 Conjugated dienes enable the formation of a highly electrophilic et

133 he regioselective functionalization of silyl-diene enol ethers under a bifunctional organocatalyst pr

134 rs giving valuable, enantio-pure skipped 1,4-diene esters (with two configurationally defined double

135 The computations are consistent with a diene-first pathway.

136 -bis(benzenesulfonyl)sulfur diimide with 1,3-diene followed by copper-catalyzed Grignard substitution

137 ial addition of a Cu-Bpin complex across the diene followed by Pd-catalyzed cross coupling with an ar

138 d the differential reactivity of the various dienes for both the initial Diels-Alder reaction and a p

139 lyloxy)pyrroles are established as competent dienes for the synthesis of para-iminoquinones.

140 A novel stereospecific mechanism for diene formation involving a vinylogous enolate intermedi

141 various alkenes and in situ formed 1-aza-1,3-dienes from the reaction of furan/pyrrole/thiophene and

142 ctive quinone oxidant, which is required for diene functionalization.

143 The ability of 1,6-diene-fused allylic sulfone to undergo efficient SO(2) e

144 ctive incorporation of nucleophiles (Nu) and dienes, giving more complex, multistereocenter containin

145 zed 1,2-carbofunctionalization of conjugated dienes has been developed.

146 nd enantioselective monohydrogenation of 1,4-dienes has been realized using an iridium catalyst with

147 ectron-deficient Pd-oxyallyls and conjugated dienes have been investigated with density functional th

148 l dehydrogenation triggers rapid, reversible diene hydrometalation en route to regioisomeric allyliri

149 eflected by an offshore downward gradient in diene II concentration in >100 surface sediments from An

150 Here we show that a source of diene II is the sympagic diatom Berkeleya adeliensis Med

151 carbon atoms-is proposed as a proxy name for diene II.

152 t the phosphadiene moiety of DPF is a potent diene in the Diels-Alder reaction and reacts with dienop

153 ydroxynicotinate followed by reaction with a diene in the presence of triethylamine afforded (4+3) cy

154 eneration of oxidation compounds (conjugated dienes in chains having also hydroperoxy/hydroxy groups,

155 upling and electrophilic substitution and as dienes in Diels-Alder cycloaddition.

156 m Morita-Baylis-Hillman alcohols to give 1,4-dienes in high yields.

157 nal bisketene equivalents for application as dienes in the Diels-Alder reaction.

158 on of C2-symmetric, 1,3-anti-diol-containing dienes in the generation of macrocyclic phosphates with

159 ed, and er's > 95:5 are obtained for several dienes including 1-alkenylcycloalk-1-enes.

160 ng storage (35 degrees C 50% RH), conjugated dienes increased more slowly in microcapsules containing

161 ion of Co-hydride intermediates that undergo diene insertion to generate Co-pi-allyl species.

162 The stereochemistry of the 1,5-diene intermediate can be controlled through the choice

163 n by the strain in the medium-ring (E,E)-1,3-diene intermediate.

164 s allows the efficient synthesis of valuable diene intermediates in good yields.

165 Insertion of 2-substituted dienes into the methanol C-H bond occurs in a regioselec

166 -H activation and migratory insertion of the diene is followed by beta-hydride elimination and hydrid

167 is to the less substituted alkene of the 1,3-diene is important for the success of these reactions.

168 s-[4+4]-cycloaddition of monosubstituted 1,3-dienes is described.

169 a direct difunctionalization of abundant 1,3-dienes is especially attractive.

170 ethod for the regiodivergent arylboration of dienes is presented.

171 ve [4+2]-cycloaddition of alkenylboranes and dienes is presented.

172 N-heteroarenes to terminal and internal 1,3-dienes is reported.

173 ntioselective hydroamination of branched 1,3-dienes is reported.

174 Diene isomerization and [4 + 2] cycloaddition, common fo

175 In contrast, s-cis constrained dienes lead to preferential formation of (4 + 2) product

176 reaction between an imine and Danishefsky's diene leading to the formation of dihydropyridinone.

177 By using a chiral diene ligand, products can be obtained with high enantio

178 n order to study the impact of regioisomeric diene ligands on the formation and catalytic activity of

179 ng a C horizontal lineC isomerization of the diene ligands.

180 as taken to interrogate the mechanism of the diene-ligated, iridium-catalyzed regio- and enantioselec

181 In some cases, a diene linkage isomerization from 3,4-eta(2) to 1,2-eta(2

182 have in common an E,Z-configured conjugated diene linked to a di- or triyne chain.

183 ital interactions of the BCN HOMO-1 with the diene LUMO.

184 Dienes metalate via tetrasolvated sodium amide monomers,

185 d as main-chain functional groups in acyclic diene metathesis (ADMET)-polymers, conferring dual respo

186 rization products (O) resulting from acyclic diene metathesis polymerization was increased from 0.55,

187 The diene methyl ethers or acetates, constructed from the Li

188 rent terminal thiocarbonylthio moiety with a diene-modified model protein.

189 cross-coupling approach to forge the central diene moiety and demonstrate this strategy by syntheses

190 nd strongly on the linker length between the diene moiety and functional group, in, e.g., PhS-(CH2)xC

191 l-ene addition copolymerization with diamide diene monomers.

192 strated as a powerful synthetic tool to form diene motifs and widely applied in the synthesis of comp

193 The diene ncAA described here is capable of producing therap

194 construct the highly substituted conjugated diene, non-Evans syn aldol, CBS reduction, Hantzsch's th

195 The Diels-Alder reaction of the photocaged diene (o-quinodimethane ether or thioether) with electro

196 acid, isomerization to a 1-arylsulfonyl 1,3-diene occurs.

197 llylic oxidation of ester-functionalized 1,4-dienes occurs at the most electron-rich double bond.

198 +2] cycloaddition and 1,2-cycloaddition with dienes + olefins, respectively.

199 oaddition involves concerted addition of the diene onto the oxidopyridinium ion.

200 ponents, a stepwise addition occurs with the diene or olefin, leading to a zwitterionic intermediate

201 bond transposition toward the conjugated 1,3-diene or the allylic oxidation is faster.

202 dienyl boronic esters has been developed via diene or triene metathesis.

203 rted transfer hydrogenative C-C couplings of dienes or CF(3)-allenes with methanol.

204 ence of protic or Lewis acids, rearranged to dienes or lupanes bearing a bicyclo[3.3.1]nonane fragmen

205 a remarkable dual role, catalyzing both the diene oxidation itself and the regeneration of the activ

206 ethod to stereoselectively establish the E,Z-diene part, an ester-tethered ring-closing metathesis/ba

207 y parametrizing both the dienophiles and the dienes partners.

208 A diene possessing a 1,2-disubstituted and 2,2-disubstitut

209 N-Boc substitution on the diene precursor changes the site of insertion of the met

210 g in situ assembly of the chiral 3-amino-1,5-diene precursor, (2) facilitating the rearrangement via

211 of ICA resolution provided information over dienes (primary oxidation compound), polyphenolic compou

212 arbonylative coupling of alkyl tosylates and dienes producing enantioenriched dienones.

213 A (6R,7S)-himachala-9,11-diene-producing sesquiterpene synthase activity was dete

214 dants do not show any reduction in conjugate diene production compared to controls, and no effect of

215 ation in both the derivatization of obtained diene products and the on-DNA synthesis of DNA-tagged di

216 Acyclic 1,4-diene products bearing either alkyl- or aryl-substituted

217 openings of the cyclobutenes give (Z,Z)-1,3-diene products, again for thermodynamic reasons.

218 ne methide and an in situ generated isomeric diene promoted by either Lewis or Bronsted acids.

219 e oxidation to afford further functionalized dienes prone for follow-up reactions.

220 to a gating effect of solvation that allows diene protonation only when the incipient ion pair is ne

221 2-Aryl and alkyl monosubstituted dienes provide alpha-aryl and alpha-alkyl alpha-methyl-s

222 E- and Z-dienes react in a stereoconvergent fashion, providing cy

223 s-Trans dienes react to give an intermediate enamine that leads

224 alpha-Oxy- o-xylylene, a highly reactive diene readily accessible from benzocyclobutenol, undergo

225 alkynes to provide unsymmetrical 3-boryl-1,4-diene reagents.

226 an appropriate chiral catalyst with a Rawal diene renders the sequence enantioselective.

227 The reactions are catalyzed by a chiral (diene)Rh(I) complex and provide a wide array of beta-ste

228 oroxines (ArBO)3 in the presence of a chiral diene-rhodium catalyst gave high yields of chiral 1,1-di

229 the presence of arylboronic acids and chiral dienes-rhodium catalyst under mild conditions.

230 that polyamide (39%) and ethylene-propylene-diene rubber (23%) were the most abundant polymers withi

231 ated by a Takai olefination, and the skipped diene side chain was introduced with a stereocontrolled

232 generated Z-products from easily accessible diene starting materials bearing a Z-olefin moiety.

233 mization of the electronic properties of 1,6-diene structures.

234 loadditions of keteniminium cations with 1,3-dienes studied experimentally by Ghosez et al. were expl

235 and survey the borylative union of allenes, dienes, styrenes and other olefins, with imines, nitrile

236 ex proved substitutionally labile undergoing diene substitution with tetrahydrofuran, NBD, or arenes.

237 astereomers was achieved using 4-substituted diene substrates.

238 3) )(2) )C(6) H(3) ](4) ) in the presence of dienes, such as 1,5-cyclooctadiene (COD) or norbornadien

239 e 1,4-difunctionalization of unactivated 1,3-dienes, such as butadiene, has been achieved by employin

240 , followed by catalytic hydrogenation of the diene system, we easily converted a dipeptide precursor

241 [4 + 2] cycloaddition, common for conjugated diene systems, were not observed during the singlet oxyg

242 A 1,1,4,4-tetracyanobuta-1,3-diene (TCBD)-aniline moiety has been introduced, for the

243 tion occurs via a concerted mechanism if the diene termini are held in close proximity, as in cyclope

244 dent of the thioesterase SphJ and yields the diene terminus of siphonazole.

245 e separation of mixtures containing alkynes, dienes, terpenes, esters, aldehydes, and ketones.

246 This feature allows dienes that are commercially available as E/Z mixtures t

247 anism involving oxidative cyclization of two dienes that determines regio- and diastereoselectivity.

248 These monocycloadducts carry semicyclic dienes that undergo a second, substrate-controlled diast

249 The reactions generate strained (E,E)-1,3-dienes that undergo spontaneous 4pi-electrocyclizations

250 alled o-quinodimethane species, a photocaged diene, that reacts in the presence of light with suitabl

251 tes with activated olefins, 1,3-dipoles, and dienes, the process generates diverse molecular architec

252 When treated with dienes, the result is a sequential [5 + 2]/[4 + 2] cyclo

253 Synthesis of skipped dienes through the hydroallylation of terminal alkyl and

254 reocontrolled 1,4-semihydrogenation of a 1,3-diene to a tetrasubstituted double bond, enzyme-catalyze

255 functionalizations of the resultant complex diene to finalize the target structure.

256 ch thereby enhances charge transfer from the diene to the imine.

257 interactions that favor the addition of the diene to the more hindered face of the dienophile, while

258 ioselective cross-[4+4]-cycloaddition of 1,3-dienes to form substituted cyclooctadienes under very mi

259 report a Rh-catalyzed hydroamination of 1,3-dienes to generate homoallylic amines.

260 reaction of a wide variety of aldehydes and dienes to give enantiomerically enriched dihydropyrans.

261 xpanded to unsaturated substrates beyond 1,3-dienes to include olefins and alkynes; this provides a n

262 time by estimating the levels of conjugated dienes, total polar compounds, polymeric compounds viz.,

263 their structural requisite for a successful diene transmissive Diels-Alder (DTDA) reaction by employ

264 ignificantly extend the preparative value of diene-transmissive Diels-Alder sequences since they offe

265 stereochemical distribution of the generated dienes under various conditions and within different pol

266 Replacing the C18-C21 diene unit of sanglifehrin with a styryl group led to po

267 s an anti-1,3-dimethyl system and a terminal diene unit, was accomplished in 10 linear steps in 7.4%

268 three bis-allylic carbons within 1,4-cis,cis-diene units.

269 across olefins) using regular olefins or 1,3-dienes up to May 2016.

270 ormation of (hetero)aryl-fused cyclohexa-1,3-dienes upon acid-promoted cyclopropyl carbinol ring open

271 the goal of selectively forming alpha,omega-diene using cis-cyclooctene as a prototypical substrate.

272 e) promote cyclopropanation reactions of 1,3-dienes using (Me(3) Si)CHN(2) .

273 alpha-amino radical species with conjugated dienes using a unified cobalt and iridium catalytic syst

274 ereoselective vicinal functionalization of a diene utilizing an intramolecular sulfinyl group as a nu

275 atalytic (3+2) cycloaddition with conjugated dienes via a Pd-aminoallyl intermediate.

276 rategy for the hydrofunctionalization of 1,3-dienes via Rh-hydride catalysis.

277 oselective approach to substituted (E,Z)-1,3-dienes was developed by using an interrupted Pummerer re

278 Silole (1-silacyclopenta-2,4-diene) was synthesized for the first time by the bimolec

279 other alcohols, epoxides, aldehydes and keto-dienes, was followed by (1)H nuclear magnetic resonance.

280 of SASFs with a range of dipoles and cyclic dienes, we report a diverse click-library of 173 unique

281 Syntheses of strained cyclic dienes were accomplished via palladium(II)-catalyzed oxi

282 -enynes or bis-silyl-functionalized buta-1,3-dienes were obtained with excellent yields and fully cha

283 These coordinated dienes were successfully taken through a second protonat

284 xidative 1,4-functionalization of cyclic 1,3-dienes where the palladium plays a remarkable dual role,

285 r the elaboration of the desired substituted dienes which will be involved in the second pericyclic r

286 atives with few examples of reactions of 1,3-dienes, which have been reported to undergo mostly 1,4-a

287 alumination of unactivated 2-substituted 1,5-dienes, which provides efficient and direct access to ch

288 the Alder-ene reaction generate acyclic 1,4-dienes, which were investigated in the selenium dioxide

289 tion of the incipient N-C bond from imine to diene while simultaneously accelerating the C-C bond for

290 Fusing 1,6-diene with allylic sulfide or allylic sulfone motifs ena

291 iastereoselective 1,4-aminothiolation of 1,3-dienes with a sulfur diimide reagent, a copper catalyst,

292 results for reactions of OsO(4)/NMO with 1,5-dienes with acid (oxidative cyclization) and without aci

293 e inverted and the reductive coupling of 1,3-dienes with aldehydes achieved.

294 dition of simple and electronically unbiased dienes with any type of aldehyde has long been unknown.

295 hydroarylation of terminal and internal 1,3-dienes with aryl pinacolato boronates is reported.

296 The reaction of 2-siloxycyclo-1,3-dienes with E-vinyldiazoacetates in the presence of the

297 t efficiently triggers the hydroarylation of dienes with electron-rich aromatic molecules.

298 phy) of PAHs containing one or more appended dienes with the ortho-quinodimethane (o-QDM) structure,

299 Deprotonation results in silyl dienes with yields from 52% to 92%.

300 and 1,5-dipoles; while reaction with cyclic dienes yields several three-dimensional bicyclic Diels-A