ライフサイエンスコーパス: dilator

1 ltrinitrate (GTN, an endothelium-independent dilator).

2 ts, SNP was administered as the experimental dilator.

3 due to the postulated additional endothelial dilator.

4 ons were biopsied and dilated with a balloon dilator.

5 applied only to the region specified as the dilator.

6 ese enzymes converted CO from constrictor to dilator.

7 duction and converted CO from constrictor to dilator.

8 holine (ACh) and mediated by endothelial NOS dilator.

9 il, the Graether 2000, and the Morcher pupil dilator.

10 ion in response to both vasoconstrictors and dilators.

11 pensatory increases in other O(2) -dependent dilators.

12 e were even less potent and less efficacious dilators.

13 dilated with an angioplasty balloon or with dilators.

14 Vessel dilator (100 ng/kg body weight per minute) given intrave

15 Vessel dilator, a 37-amino acid peptide hormone synthesized in

16 terial infusion of the endothelium-dependent dilator acetylcholine) in healthy volunteers before and

17 administration of the endothelium-dependent dilator acetylcholine.

18 achial infusion of the endothelium-dependent dilators acetylcholine (ACh) and bradykinin (BK) and the

19 ngs in response to the endothelium-dependent dilators acetylcholine and A23187 was greater in rings i

20 bral arterioles to the endothelium-dependent dilator, acetylcholine (10 micromol/L) was blunted in Mt

21 tters and hormones with both constrictor and dilator actions during hibernation are described.

22 ea (OSA) require increased pharyngeal muscle dilator activation during wakefulness to maintain upper

23 apy may be related to increased upper airway dilator activity in sleep and/or enhanced slow-wave slee

24 triction competes with endothelium-dependent dilator activity to determine post-exercise arterial fun

25 ed sleep-related suppression of upper airway dilator activity, p < 0.02.

26 in both airflow and pharyngeal airway muscle dilator activity, precipitating airway obstruction.

27 c was not mediated by changes in endothelial dilator activity.

28 ayer, which includes a marked increase in NO dilator activity.

29 response curves to different constrictor and dilator agonists were obtained at an intraluminal pressu

30 illary block was not as large as that of the dilator anatomy according to the quantified values of AO

31 l thickness iris) to quantify the effects of dilator anatomy, (2) in the presence (+PB) versus absenc

32 uction may contribute to impaired functional dilator and hyperaemic responses at the venular level.

33 the cremaster muscle (0.5, 1, 3 Hz), venular dilator and hyperaemic responses to lower frequencies we

34 STG, including the activation of the pyloric dilator and pyloric neurons, an increase in the pyloric

35 activity was present in ciliary muscle, iris dilator and sphincter muscles, and blood vessel smooth m

36 ttenuation of vasodilation to cAMP-dependent dilators and enhanced vasoconstriction to ET-1.

37 The use of different dilators and tract size continues to be examined.

38 x, the physiology of the upper airway muscle dilator, and the stability of ventilatory control are im

39 The upper airway dilators are much more susceptible to a decrease in musc

40 The pyloric dilator axons of the stomatogastric nervous system in th

41 ageal dilation, performed either with Savary dilators/bougie or hydrostatic balloon, is an effective

42 er vaccination) to the endothelium-dependent dilator bradykinin (BK) and the endothelium-independent

43 The peptide dilators calcitonin gene-related peptide (CGRP) and vaso

44 e (NO)-mediated artery function, and conduit dilator capacity (DC), a surrogate marker for arterial r

45 e was no evidence that adenosine can release dilator concentrations of K+ from skeletal muscle fibres

46 ictor response distinct from the multiphasic dilator/constrictor response to adenosine.

47 TER FROM 3.0 TO 5.4 MM IN 10 SECONDS, ACTIVE DILATOR CONTRACTION WAS APPLIED BY IMPOSING STRESS IN TH

48 The posterior location of the dilator contributes to the anterior iris bowing via a no

49 (4 mum, 1% of full thickness) versus a thick dilator (covering the full thickness iris) to quantify t

50 Dilators decrease central pressures by increasing venous

51 Vessel dilator decreased systemic vascular resistance 24%, pulm

52 lthough symptoms are treated with a range of dilator drugs.

53 erial infusion of ACh (endothelium-dependent dilator) during resting conditions, handgrip exercise (5

54 ABSTRACT: Endothelial dilator dysfunction contributes to pathological vascular

55 AJ activity can account for the endothelial dilator dysfunction in old arteries.

56 junctions, which contributes to endothelial dilator dysfunction.

57 men with higher VM/VP ratios (i.e., greater dilator effect of a DI) tended to have greater methachol

58 nteric arteries (MAs) and veins (MVs) to the dilator effect of CCBs.

59 Second, the possible dilator effect of endothelin-B receptor activation was t

60 the constrictor effects exceeds that of the dilator effects by the magnitude of the TGF response.

61 lium is involved in both the constrictor and dilator effects of endothelin in rat pulmonary artery, c

62 ute hypertension and (2) block nNOS-mediated dilator effects of N-methyl-D-aspartate (NMDA) delivered

63 Vessel dilator enhanced sodium excretion 3- to 4-fold in CHF su

64 hypoxia is attenuated and replaced by other dilator factors.

65 ng the possibility that both constrictor and dilator fibres are present.

66 Carbachol was the most efficacious dilator, followed by isoprenaline.

67 operative anal dilatation using a 33 mm anal dilator for 20 min, while the second group did not.

68 ased screening method for identifying potent dilators from among the many thousands of available bitt

69 es of pravastatin-treated monkeys had better dilator function and plaque characteristics more consist

70 The endothelial dilator function appeared normal.

71 o adrenergic agonists as well as endothelial dilator function did not differ between PS and controls.

72 dministered high-dose folic acid on coronary dilator function in humans.

73 further characterization of constrictor and dilator function in mesenteric and caudal femoral arteri

74 ELISA), and its effect on cell viability and dilator function in mouse aorta were assessed.

75 Endothelial-dependent dilator function was determined by the topical applicati

76 Endothelial-dependent dilator function was preserved with PR.

77 oth muscle dilation (endothelial-independent dilator function) in all groups.

78 ss, together with testing of constrictor and dilator function.

79 mia adversely effects coronary microvascular dilator function.

80 While individual vasoconstrictor and dilator genes have been identified, the coordination of

81 dykinin (BK) and the endothelium-independent dilator glyceryl-trinitrate (GTN).

82 These results indicate that vessel dilator has significant beneficial diuretic, natriuretic

83 There was a significant correlation between dilator impairment and the degree of dyslipidemia record

84 p38 MAPK inhibitor, SB203580, prevented NMDA dilator impairment significantly less than the ERK MAPK

85 ve anal dilatation using a standardized anal dilator in reducing post-operative pain.

86 es to endothelium-dependent and -independent dilators in the ovine fetal pulmonary circulation.

87 onses to ET-1 and iloprost, a cAMP-dependent dilator, in vivo, plus the effects of such treatment on

88 of PGs also depend on other O(2) -dependent dilators including ATP, adenosine and NO.

89 also suggest that adenosine had little tonic dilator influence in CH rats breathing 12% O2 despite it

90 rats were more sensitive than N rats to the dilator influence of acute systemic hypoxia and this was

91 We suggest that in CH rats, the dilator influence of adenosine in acute hypoxia occurs v

92 Exposure to ONOO(-) reduced the dilator influence of K(v) channels in RSCAs.

93 to HG for 24 h showed a loss of K(v) channel dilator influence that also was partially restored by th

94 cle vasculature are largely blunted by local dilator influences, despite high instantaneous frequenci

95 lature after hemorrhage in favor of enhanced dilator mechanisms in premucosal vessels with enhanced c

96 ion was designed to determine whether vessel dilator might have similar beneficial effects in persons

97 ctions in serotonin delivery to upper airway dilator motoneuron activity may contribute to sleep apne

98 eceptor subtypes implicated in excitation of dilator motor neurons was evaluated in anesthetized, par

99 Pharyngeal dilator muscle activation (GGEMG) during wakefulness is

100 of local mechanisms in mediating pharyngeal dilator muscle activation in normal humans during wakefu

101 small upper airway with augmented pharyngeal dilator muscle activation maintaining airway patency awa

102 ortant in mediating the increased pharyngeal dilator muscle activation seen in sleep apnea patients d

103 imulus) were important in driving pharyngeal dilator muscle activation, one would predict that during

104 ich could not be explained by differences in dilator muscle activation.

105 aoral surface electrode to record pharyngeal dilator muscle activity (the genioglossus [EMGgg] normal

106 aoral surface electrode to record pharyngeal dilator muscle activity (the genioglossus [EMGgg]), we e

107 t cholinergic signaling impairs upper airway dilator muscle activity by suppressing glutamatergic inp

108 pper airway collapse is decreased pharyngeal dilator muscle activity during sleep.

109 ep apnea (OSA) may have augmented pharyngeal dilator muscle activity during wakefulness, to compensat

110 of two serotonin antagonists on upper airway dilator muscle activity, diaphragm activity, Sao2, and u

111 With reductions in dilator muscle activity, upper airway cross-sectional ar

112 riven primarily by posterior location of the dilator muscle and by dynamic pupillary block, but the e

113 pupillae muscle, iris pigment epithelium and dilator muscle complex, nonpigmented and pigmented epith

114 is, we assessed the relationship between two dilator muscle electromyograms (EMGs, i.e., genioglossus

115 ng (high loop gain), and impaired pharyngeal dilator muscle function.

116 nificantly lower values of iris thickness at dilator muscle region (DMR) found in treated subjects (P

117 Iris dilator muscle region (DMR) thickness, sphincter muscle

118 and collapsibility and enhanced upper-airway dilator muscle responses to avoid OSA.

119 The genioglossus is an upper airway dilator muscle, the length of which is directly related

120 ugh alpha-adrenergic stimulation of the iris dilator muscle.

121 chanics, ventilation, plus activation of two dilator muscles (genioglossus [GG] and tensor palatini [

122 Pharyngeal dilator muscles are clearly important in the pathogenesi

123 Pharyngeal dilator muscles are clearly important in the pathogenesi

124 Pharyngeal dilator muscles are clearly important in the pathophysio

125 Pharyngeal dilator muscles are important in the pathophysiology of

126 Upper airway dilator muscles are phasically activated throughout brea

127 The stimuli controlling pharyngeal dilator muscles are poorly defined.

128 ay have augmented serotonergic control of UA dilator muscles as a mechanism to prevent pharyngeal col

129 ta provide strong evidence that upper airway dilator muscles can be activated throughout inspiration

130 he complex lumen and marked expansion of the dilator muscles characteristic of 50- and 100-day untrea

131 activation is similar to that of pharyngeal dilator muscles during spontaneous and induced apneas, a

132 n is in the nucleus ambiguus innervating the dilator muscles of the soft palate, pharynx, and larynx,

133 lar to skeletal postural muscles, pharyngeal dilator muscles responsible for maintaining an open uppe

134 mitigated by highly responsive upper-airway dilator muscles to avoid OSA.

135 way anatomy, (2) the ability of upper airway dilator muscles to respond to rising intrapharyngeal neg

136 increased mechanoreflex-mediated activity of dilator muscles while awake, but this reflex is inhibite

137 Proper function of pharyngeal dilator muscles, including the genioglossus muscle of th

138 neuropil and orthodromically to the pyloric dilator muscles.

139 lung volume, and dysfunctional upper airway dilator muscles.

140 and positional therapy (CAPT; external nasal dilator, nasal saline lavage with mometasone, mouth tapi

141 ate block, our data suggest that sympathetic dilator nerves are not responsible for limb vasodilatati

142 d to all six modulators, but the ventricular dilator neuron only responded to a subset of them.

143 imental phase resetting curves for a pyloric dilator neuron show satisfactory agreement.

144 xon of the crustacean stomatogastric pyloric dilator neuron.

145 he pyloric (PY) neurons, and the ventricular dilator neuron.

146 , gastric mill, lateral pyloric, and pyloric dilator neurons from male crabs of the species Cancer bo

147 We studied the axons of the pyloric dilator neurons in the stomatogastric nervous system of

148 tion being mediated by sensory nerve-derived dilator neuropeptides CGRP and substance P, and also nNO

149 dykinin (BK) and the endothelium-independent dilators NTG and verapamil (resistance vessel response).

150 or pupil expansion include the Beehler pupil dilator, nylon iris hooks, and pupillary rings, includin

151 Strikingly, acetylcholine, a powerful dilator of most vascular beds, virtually lost the abilit

152 Relaxin is a powerful dilator of systemic resistance arteries secreted by the

153 , organic nitrates are established selective dilators of conduit arteries.

154 t pial arteries constricted and responses to dilator opioids were blunted after fluid percussion inju

155 , five occurred during passage of the bougie dilator or nasogastric tube, and two occurred after surg

156 e normal 1:1 alternation between the pyloric dilator (PD) and LP neurons to patterns of 2:1, 3:1, or

157 The pyloric dilator (PD) neuron exclusively expresses D2Rs.

158 roperties and synaptic output in the pyloric dilator (PD) neuron, in part by reducing calcium current

159 lateral pyloric (LP) neuron and the pyloric dilator (PD) neurons after blocking action potential-med

160 The two pyloric dilator (PD) neurons are active in the pyloric rhythm, h

161 ic circuit of the spiny lobster, the pyloric dilator (PD) neurons are members of the pacemaker group

162 ndent Ca(2+) accumulation in the two pyloric dilator (PD) neurons of the pyloric network in the spiny

163 We previously showed that, in pyloric dilator (PD) neurons of the stomatogastric ganglion (STG

164 he peripheral motor axons of the two pyloric dilator (PD) neurons of the stomatogastric ganglion in t

165 sion in the two electrically coupled pyloric dilator (PD) neurons showed significant interanimal vari

166 hereas the anterior burster (AB) and pyloric dilator (PD) neurons were rhythmically active at a low f

167 Proctolin additionally acts on the pyloric dilator (PD) neurons, the pyloric (PY) neurons, and the

168 se and confirmed their expression in pyloric dilator (PD) neurons, which are part of the pacemaker ke

169 solate the anterior burster (AB) and pyloric dilator (PD) neurons.

170 pse from the lateral pyloric (LP) to pyloric dilator (PD) neurons.

171 burst amplitude and duration in the pyloric dilator (PD) neurons.

172 temperature, while the phases of the pyloric dilator (PD), lateral pyloric (LP), and pyloric (PY) neu

173 cemaker neurons anterior burster and pyloric dilator (PD).

174 s: the anterior burster (AB) and the pyloric dilator (PD).

175 The single-dilator percutaneous tracheostomy technique is a safe, c

176 e (average 70%), showing that the anatomy of dilator plays an important role in iris deformation duri

177 pha-TRPV4 signaling was upregulated, whereas dilator pressure-TRPV4-BK channel signaling was disrupte

178 on, and a single muscle group--the laryngeal dilators--produces underwater calls.

179 ecause of an enhanced release of endothelial dilator prostaglandins and suggest that this vascular ad

180 dulated by substances such as endothelin and dilator prostaglandins, normoxic contraction is an intri

181 dilation, suggesting that it was mediated by dilator prostaglandins.

182 omerulus may counteract the effects of these dilator prostanoids and increase glomerular resistance.

183 ty of the iris to dilate owing to absence of dilator pupillae muscle.

184 IAs in the lateral pyloric (LP) and pyloric dilator (PY) cells, and the Drosophila shal current.

185 The impaired dilator reactivity in OZR reflects a loss in venular nit

186 Hypoxia enhanced dilator reactivity to sodium nitroprusside, the large co

187 rvested and, in one segment, constrictor and dilator reactivity was determined by wire myography.

188 , both post-capillary and collecting venular dilator reactivity within the skeletal muscle of obese Z

189 ACTION WAS APPLIED BY IMPOSING STRESS IN THE DILATOR REGION.

190 Furthermore, folate increased dilator reserve by 83% in abnormal segments (0.77 +/- 0.

191 in/g, placebo vs. folate, p < 0.05), whereas dilator reserve in normal segments remained unchanged (2

192 The dilator response (P < 0.05) and sensitivity (P < 0.05) t

193 infusion also resulted in greater epicardial dilator response after ACh among African Americans.

194 have a role in temperature sensation or the dilator response in human skin.

195 spontaneous myogenic tone, but enhanced the dilator response of penetrating arterioles to extralumin

196 perfusion (7.7+/-1.5% to 3.5+/-0.9%) and the dilator response of resistance vessels to acetylcholine

197 IR did not reduce the dilator response of the radial artery to glyceryltrinitr

198 gliben-clamide-sensitive afferent arteriolar dilator response to 1 microM PCO-400 (a benzopyran K(ATP

199 In addition, women with abnormal coronary dilator response to acetylcholine had less time free fro

200 LIGRL was selectively preserved, whereas the dilator response to acetylcholine was converted to const

201 rictor response to endothelin-1 and enhanced dilator response to acetylcholine was observed in CYP2J2

202 Animal studies have demonstrated that the dilator response to exogenous nitrovasodilators is exagg

203 However, neither the dilator response to nitroglycerin (21 +/- 14% vs. 18 +/-

204 None of the therapies improved the dilator response to nitroglycerin (all P>/=0.184).

205 no correlation between the magnitude of the dilator response to nitroglycerin and acetylcholine.

206 No therapy improved the dilator response to nitroglycerin.

207 contrast, in the umbilical vascular bed, the dilator response was not only prevented but reversed to

208 red for transmission or manifestation of the dilator response.

209 ation of other ion channels in mediating the dilator response.

210 with hypoxia, due to a smaller compensatory dilator response.

211 nistic effects on epicardial coronary artery dilator responses in atherosclerotic monkeys.

212 e of tamoxifen on epicardial coronary artery dilator responses in atherosclerotic, ovariectomized mon

213 n receptor as a modulator of coronary artery dilator responses in ovariectomized, atherosclerotic mon

214 Blood pressure, and constrictor and dilator responses in the aorta and mesenteric resistance

215 ed impairment of NO and K+ channel-dependent dilator responses may be responsible for the increased r

216 Estrogens have been shown to improve dilator responses of atherosclerotic coronary arteries.

217 The dilator responses of femoral arterial rings to acetylcho

218 ponses to air in CH, but reversed or reduced dilator responses to 12% O2 in N rats (to -2.4 +/- 1.3%

219 t of chronic 17beta-estradiol replacement on dilator responses to acetylcholine and sodium nitropruss

220 Similarly, dilator responses to acidosis were reduced by nearly 60%

221 ease), brachial artery endothelium-dependent dilator responses to hyperemia by ultrasonography (as an

222 predicted by a simple sum of the individual dilator responses to hypoxia alone and normoxic exercise

223 iography was used to measure coronary artery dilator responses to intracoronary infusions of acetylch

224 Dilator responses to leucine enkephalin and dynorphin, e

225 However, whether arteriolar dilator responses to NMDA are reduced during arterial hy

226 en-dependent, cytochrome P450 (CYP)-mediated dilator responses to shear stress in arterioles of NO-de

227 tion and enhanced third-order femoral artery dilator responses to the H(2)S donor sodium hydrosulphid

228 They also showed similar maximum dilator responses to topical adenosine (10(-3) M); 14.1

229 constricted or dilated with ACH had similar dilator responses with BK.

230 Additionally, with the impaired dilator responses, a modest increase in adrenergic const

231 Nitric oxide (NO) and K+ channel-mediated dilator responses, elicited by acetylcholine, iloprost,

232 h superoxide dismutase restored all examined dilator responses.

233 l muscle that is associated with accentuated dilator responsiveness to acute hypoxia and dilator subs

234 PSD95 appears to function as a critical 'dilator' scaffold in cerebral arteries by increasing the

235 The possible contribution of an endothelial dilator secondary to activation of adenosine receptors o

236 This enhanced dilator sensitivity is most evident in small premucosal

237 els within the physiological range, enhances dilator sensitivity of the coronary microcirculation thr

238 nitroprusside and the endothelium-dependent dilators serotonin, A23187, and substance P were obtaine

239 e, for example by facilitating conduction of dilator signals upstream.

240 ose responses to the endothelium-independent dilator sodium nitroprusside and the endothelium-depende

241 ig, pial arteries constrict and responses to dilator stimuli, including opioids, are blunted.

242 vessels to both physical and pharmacological dilator stimuli.

243 reased, consistent with removal of a hypoxic dilator stimulus that is waning in 7CH rats.

244 dilator responsiveness to acute hypoxia and dilator substances that are NO -dependent.

245 The contribution of the nitric oxide (NO) dilator system to cutaneous endothelial dysfunction is c

246 acheostomy by either the single- or multiple-dilator technique described by Ciaglia.

247 ue in 6:01 +/- 3:03 mins and by the multiple-dilator technique in 10:01 +/- 4:26 mins (p <.0006).

248 tracheostomy was performed using the single-dilator technique in 6:01 +/- 3:03 mins and by the multi

249 l tracheostomy than for the Ciaglia multiple dilator technique, pooled risk difference 0.12 (95% CI,

250 rs and to determine the efficacy of coronary dilators to attenuate their action.

251 ckade to reduce constrictor tone and augment dilator tone.

252 provide tonic, NO-dependent cerebrovascular dilator tone.

253 c oxide, contribute to resting microvascular dilator tone.

254 t one intrinsic neuron type, the ventricular dilator (VD) neuron, a highly organized and stereotyped

255 e discharges in the motoneurons: ventricular dilator (VD), PY, and LP.

256 ts only when the proper anatomic position of dilator was used.

257 eptive reflexes to phasic activity of airway dilators, we assessed genioglossal electromyogram (GG EM

258 icromol/L papaverine, a direct smooth muscle dilator, were impaired with the HM/LF diet in wild-type

259 nitroprusside (SNP; endothelium-independent dilator) which served as a high-flow control condition (

260 eater vascular occlusion and accumulation of dilators, while blunted hyperaemia in BAs may reflect lo