ライフサイエンスコーパス: directly

1 mer-ID method have analyzed clinical samples directly.

2 ng depth and analyze the original count data directly.

3 uatic animals by grabbing prey whilst flying directly above, or floating upon (less likely), the wate

4 le at the data point level enabling users to directly access and download any subset of signatures ac

5 We show here that XBP-1s can directly activate ORF21 and that this activation is medi

6 ted herpesvirus (KSHV) lytic replication and directly activate viral interleukin-6 (vIL-6).

7 lar regulator of mitochondrial function that directly activates cytochrome c oxidase in the mitochond

8 e than 1 order of magnitude on average after directly adding a small amount (e.g., 2 mM) into TFA mob

9 The paucity of public health messages that directly address communities of color might contribute t

10 We now directly address this question for NMDA receptor-depende

11 One fundamental question that remains to be directly addressed is whether the structure and function

12 These methods include directly administering the peptides ex vivo (i.e., to ex

13 7 currents; however, siRNA knockdown did not directly affect action potential morphology.

14 ventions such as inhibitors or mutations can directly affect its activity state without changing its

15 ment is a crucial part of critical care that directly affects morbidity and mortality.

16 ses infectious disease risk, a question that directly affects policy decisions for biodiversity conse

17 istribution of PZC and electric field, which directly affects the electrochemical energy storage and

18 d show that the position of the resulting CO directly affects the formation of distinct chromosome su

19 patients with progressive multiple sclerosis directly after autopsy, at 3 T, using T1 and proton-dens

20 s and drug metabolites are known to interact directly and indirectly (through irreversible protein bi

21 seq approaches we identified genes regulated directly and indirectly by RFX1, RFX2 and RFX3 in mouse

22 e related to periodontal diseases, which are directly and indirectly mediated by oral bacteria.

23 The true population LD cannot be measured directly and instead can only be inferred from genetic s

24 In summary, we show that ERFE binds BMP6 directly and with high affinity, and that antibodies tar

25 rged, including multiplexed molecular panels directly applicable to blood and blood culture specimens

26 e of CKD, but there is no feasible method to directly assess Pglom in humans.

27 To directly assess the impact of cellular p53 status on CRI

28 Yet few studies have directly assessed ancestral variation in plasticity and

29 king exposure during the prenatal period was directly associated with differential expression of 14 g

30 ult to determine whether actin filaments are directly associated with specific membranes.

31 chromatin decompaction and nuclear shape by directly associating with the DNA.

32 ntaining the secreted Malibu-Glo reagent can directly be used for detection of cell surface antigens

33 t KBTBD13 localizes to the sarcomere and can directly bind actin.

34 ing evidence has indicated that circRNAs can directly bind proteins and participate in a myriad of di

35 Further analysis revealed that BZR1 could directly bind to the promoter of RESPIRATORY BURST OXIDA

36 describe a role for intestinal bile acids in directly binding and neutralizing TcdB toxin, the primar

37 gene that is involved in DNA replication by directly binding to specific motifs within their promote

38 -invasive and pro-metastatic effects through directly binding to Vimentin and competitively abrogatin

39 , in vitro experiments demonstrate that TAN1 directly binds microtubules, mediating microtubule zippe

40 Activated purified CaMKIIalpha also directly binds Shank3 between residues 829 and 1130.

41 We demonstrate that FDL1 directly binds to CCAACC core motifs present in AD1 regu

42 o eukaryotic protein kinases, and that MOB1A directly binds to the LegK7 kinase domain.

43 cular FRET analysis, we demonstrate that SWG directly binds to the lipid-binding cavity of OSBP.

44 Because STING directly binds to TRIF, we identified the STING-interact

45 ed CST complex binds to 5' DNA overhangs and directly blocks MRE11 degradation in vitro, and the DNA-

46 btained by controlling the functional groups directly bonded to the nitrogen atom of the ynamides.

47 ive approach is to change the magnetic state directly by acting on the interaction between magnetic m

48 energy cycling and thus surface temperature directly by altering surface physical properties (e.g.,

49 Furthermore, we show that GacB is inhibited directly by cyclic di-GMP, which provides evidence for c

50 rominent manifestation of the disease caused directly by the genetic defect, including other primary

51 n platelet-type 12-lipoxygenase (12-LOX) can directly catalyze the regioselective and stereospecific

52 In this work we directly compare the kinetics of photoreduction of six d

53 Few studies directly compared different tests, scores, cut points, o

54 Herein, we directly compared the in vitro chondrogenic potency of T

55 d that (18)F-JK-PSMA-7 was not inferior when directly compared with (68)Ga-PSMA-11 in a pilot study b

56 across internal interfaces, as supported by directly comparing the apparent diffusivities of the two

57 noisy nature of current regulatory networks, directly comparing the gains and losses of targets of ke

58 detection techniques have been reported for directly confirming the localized presence of the templa

59 " the US biomedical research enterprise must directly confront the reality of structural racism in sc

60 we propose DiNeR, a computational method to directly construct a differential TF co-regulation netwo

61 al changes are local and limited to subunits directly contacting bound cofilin.

62 s alters interactions with the ribosome that directly contribute to misreading.

63 continuous flow process is presented, which directly converts isoxazoles into their oxazole counterp

64 (13)C, and (15)N resonances for the ligands directly coordinating the metal center.

65 hat gives information of the capacitance, is directly correlated with concentrations.

66 crease in stiffness in human lenses that was directly correlated with levels of protein-cross-linking

67 anscriptomic changes, including NPPB levels, directly correlated with sarcomere function and can be u

68 alling sequence and that readthrough of SecM directly correlates with the stability of the RNH foldin

69 As reproductive outcome is directly coupled to evolutionary success, the underlying

70 oice has complex acoustic qualities that are directly coupled to peripheral musculoskeletal tensionin

71 ightning strikes, we estimate that lightning directly damages c.

72 uggests that pathogens that reduce yields by directly damaging harvestable plant tissues have receive

73 ic livestock by hunter-gatherers in Lesotho, directly dated to the seventh century AD at Likoaeng and

74 at holographic particle characterization can directly detect binding of proteins to functionalized co

75 poxia-inducible transcription factors (HIFs) directly dictate the expression of multiple RNA species

76 While not directly discernable, PopZ fills a region at the cell po

77 targetable, with reports of strategies that directly disrupt either the RAS interaction with activat

78 zed for probe-free applications: Domains are directly distinguished from the surrounding membrane by

79 .9 billion people living in (0.3 billion) or directly downstream of (1.6 billion) mountainous areas.

80 hannels and G protein-coupled receptors, has directly enabled the discovery of most drugs developed t

81 canonical modes of chromatin remodelers that directly engage and remodel nucleosomes or transcription

82 pment of novel intermolecular reactions that directly engage the arene pool.

83 Rather, the proteostasis network directly engages the misfolded C-Pro domain itself to pr

84 the open-activated state but that it may not directly enter the selectivity filter.

85 ite these findings, to date, no studies have directly examined how O-GlcNAcylation modulates the effi

86 Our results show that PTBP1 directly exploits the tendency of UPF1 to release RNA up

87 s many of these proteins bind actin monomers directly, formins use the actin-binding protein profilin

88 Method (M3) extracts output directly from a commercial platform with an undisclosed

89 CH=CH-) covalent organic framework, COF-701, directly from acetonitrile, a cheap commodity solvent, b

90 communities by isolating and sequencing DNA directly from an environment (metagenomics).

91 report the preparation of rare sugar isomers directly from biomass carbohydrates through site-selecti

92 accuracy in identifying MMR-D and TMB-H ECs directly from CE-CT.

93 an selectively extract and separate MCCA oil directly from chain-elongating bioreactor broth with jus

94 ming growth factor (TGF) beta-1 or generated directly from cultured BM treated with TGF beta-1 was pu

95 is difference in structural behavior follows directly from hydrogen-bonding restrictions and suggests

96 s, the main pushing machinery in cells, grow directly from microtubule tips toward the leading edge i

97 or the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens.

98 Bacterial RNA extracted directly from oropharyngeal swabs and evaluated by quant

99 d to handle, restrain, and collect specimens directly from pigs thus providing an approach to emergin

100 ty to spatially resolve molecular biomarkers directly from sectioned tissues.

101 lates and identify probable diphtheria cases directly from specimens.

102 atically reconstructs 3D whisker information directly from the 'stereo' video data.

103 the label-free study of enzymatic reactions directly from the bioassay matrix with an effective anal

104 ntelligence in Medical Technologies database directly from the carotid ultrasound device.

105 ptic shock and S. aureus bacteremia admitted directly from the emergency department to the ICU from J

106 extracting the velocity and pressure fields directly from the images is challenging.

107 substrates, we show that unfolding can occur directly from the initial closed-channel complex.

108 , and other surrounding brain areas, but not directly from the mushroom bodies.

109 fected by bacteria were selected and sampled directly from the tissue without cell manipulation throu

110 cessful attempts to target the small GTPases directly have resulted in them being classed as "undrugg

111 Using a high-throughput approach, we have directly identified specific metabolites that exert tran

112 recordings from ENs of larval zebrafish that directly illustrate how synaptic inhibition and excitati

113 We directly image defect nanodomains in the MOF UiO-66(Hf)

114 transmission electron microscopy is used to directly image Neel-type skyrmion lattice and the stripe

115 ncubate HA for different times at pH 5.0 and directly image structural changes using single-particle

116 The state-of-the-art microscopy directly images atomic/molecular configurations in thin

117 We show here that at low doses these SCFAs directly impact B cell intrinsic functions to moderately

118 Disruptions in this equilibrium directly impact neutrophil numbers in circulation, cell

119 change and increasing world population will directly impact the global food supply chain linkages.

120 on of the tRNA pool and thus presumed to not directly impact translation.

121 uld be designed to determine if our findings directly impact vaccine effectiveness.

122 resistance to overwash, as opposed to being directly impacted by major storms.

123 -2 residues protruded out from the cleft and directly impacted KIR3DL1 engagement.

124 Here we add that arginine also directly impacts bacterial virulence.

125 delay between injury and polyplex injection directly impacts the magnitude of transfection efficienc

126 nd kidney was not perfused with EVNP and was directly implanted to a 64-year-old patient.

127 erence data, we parcellated the entire brain directly in 3D, labeling every voxel with a brain struct

128 We have shown that dried milk can be used directly in alkaline-catalysed methylation, whereas dire

129 strategy to manipulate vHPC-NAc excitability directly in awake behaving mice.

130 of the extracellular and bath or blood pool directly in contact with electrodes that exhibit a press

131 y to examine the transition-metal resonances directly in MXene samples, and the first (93)Nb NMR of a

132 esolution microscopy to study TNFR1 assembly directly in native cellular settings and at physiologica

133 e in health laboratory environments but also directly in places where humans circulate and spread the

134 d conspecific versus heterospecific stimuli, directly in the field and in two contexts (allopatry vs.

135 caffolding causes communities to participate directly in the process of evolution by natural selectio

136 probabilistic nature allows them to be used directly in unbiased evaluation of synergistic efficacy

137 Furthermore, the ability of mCD40L to also directly induce cell death in CD40-expressing carcinomas

138 onical electronic-structure calculations, we directly infer the coupled electron transfer, which we f

139 rus to identify the cortical areas that most directly influence parasympathetic and sympathetic contr

140 sight on how initiating oncogenic events may directly influence the selection of secondary concomitan

141 ope V3 loop, this viral determinant does not directly influence V3 loop bnAb sensitivity.

142 lationship between FASN, RhoU and Cdc42 that directly influences cell migration potential.

143 pe the experience of watching joint actions, directly influencing how beautiful and enjoyable we find

144 ion to its ability to downregulate c-MYC and directly inhibit tumor cell proliferation, NHWD-870 bloc

145 type Ca(2+) channel (Cav1.2) antagonist that directly inhibits calcium influx and smooth muscle contr

146 e delivery approach to alter CaM function by directly injecting adenoviruses expressing CaM-wild type

147 unknown how broadly RBPs and ERV transcripts directly interact to provide a posttranscriptional layer

148 findings, showing that anionic AuNPs do not directly interact with embedded gA channels but perturb

149 We reported that osteocytes (Ocys) directly interact with MM cells to increase tumor growth

150 IFT54 directly interacted with IFT dynein subunit D1bLIC, and

151 These findings suggest that Tspan15 directly interacts with ADAM10 in a functional scissor c

152 For the first time, we demonstrate that RocA directly interacts with itself (RocA) and CovS, but not

153 )-ICD fused to maltose-binding protein (MBP) directly interacts with RIC-3, without the involvement o

154 olymersomes to deliver encapsulated payloads directly into cell nuclei.

155 udy was to determine whether IRMA may evolve directly into NV.

156 e therapeutic outcomes, we microinjected ASO directly into the E12.5 inner ear.

157 he gill chambers of jawless vertebrates open directly into the environment, jawed vertebrates evolved

158 Although live coral tends not to face directly into the prevailing current direction, preferri

159 ls have also incorporated the mirGFF3 format directly into their code, such as, miRge2.0, IsoMIRmap a

160 Using the microphytobenthos community to directly introduce a pulse of labile carbon into sedimen

161 cted cells, vNr-13 expression appeared to be directly involved in the disruption of the mitochondrial

162 Although Hubei Province was seldom directly involved in the food trade, it experienced subs

163 ng enzyme 1 (IRE1alpha) branch of the UPR is directly involved in the polarization of macrophages in

164 To discern whether chaperones were directly involved in Ubr1-mediated ubiquitination, we de

165 elial CD8(+) T-cell lines, or CD8(+) T cells directly isolated from intestinal biopsies, with gammac

166 On the other hand, the ROS not only directly kills tumor cells by photodynamic therapy but s

167 Directly linked porphyrin dimers have attracted consider

168 ing fluids where organic functionalities are directly linked through the Si-C bond, unlike the indust

169 ron flux through redox buffering circuits is directly linked to changes in oxygen consumption mediate

170 The latter was directly linked to greater oral hygiene effectiveness.

171 ct proxy for reliably assessing Pb emissions directly linked to human activities.

172 product of cosmic rays which are themselves directly linked to solar activity and the earth magnetic

173 information; many of these regions have been directly linked to the neurobiology of pair bonding in m

174 In contrast with previous therapeutics directly linking Dox and TF, cytotoxicity of CDT resulte

175 Our structure directly links LA and S, setting the stage for intervent

176 al based therapies, including the ability to directly manipulate disease mechanisms, selectively targ

177 Now, by directly manipulating E7 binding to PTPN14 and using a P

178 the vicinity of the conical intersection is directly mapped by the proposed experiment.

179 ional analysis of the functional surfaces to directly measure Syt1-membrane interaction and fully map

180 cule orientation localization microscopy, to directly measure the orientation spectra (3D orientation

181 we use massively parallel reporter assays to directly measure the transcriptional outputs of thousand

182 heimer's disease (AD), but the impact of the directly measured iron on the clinical syndrome has not

183 itation of estimating g(m) , which cannot be directly measured, and (iv) how g(m) responds to long- a

184 electrochemical measurements, the OCP method directly measures the overall PCET reaction thermodynami

185 However, the implementation of cameras directly mimicking the eyes of common arthropods is comp

186 Proinflammatory cytokines directly modulate RANKL/OPG expression and consequently

187 2-AG directly modulates pathogen function by inhibiting virul

188 A nanofluidic device directly monitors the protein size and quantity in the c

189 influence on air temperatures and winds, or directly, mostly through its effects on ice shelves.

190 intact high-titer infectious prions are not directly neurotoxic.

191 We have directly observed sub-gap states significantly lower in

192 Eight-day inpatient directly observed therapy confirmed nonadherence as the

193 We analysed directly obtained and imputed genotypes, and followed-up

194 ions with glycans at the single-virion level directly on living mammalian cells, which offers new per

195 entire timespan, while fixed decoders based directly on the recorded neural activity degraded substa

196 Here, the growth of layers of organothiols directly onto muscovite mica is demonstrated using a sim

197 SG cargoes (phogrin and VMAT2) does not sort directly onto SGs during budding, but rather exit the TG

198 ffects all cells of the immune system either directly or after hydrolysis to adenosine.

199 Cancer therapies aim to kill tumor cells directly or engage the immune system to fight malignancy

200 suggesting that the increased H3K27me3 could directly or indirectly contribute to the transcription r

201 nt productive anti-tumor immune responses by directly or indirectly excluding effector CD8+ T cells f

202 ted downstream signaling kinases which might directly or indirectly influence neutrophil responses to

203 examining how CodY controls gene expression directly or indirectly, virtually nothing is known about

204 rolling the decision between forming neurons directly or indirectly.

205 Chemical biology strategies for directly perturbing protein homeostasis including the de

206 AURKB directly phosphorylates MYC at serine 67, counteracting

207 lop a secondary random-forest classifier for directly predicting asthma severity.

208 the multi-organ pathology of Bbs2-/- mice by directly preserving ciliary structure and function towar

209 remained elusive due to a lack of methods to directly probe nanoscopic membrane features.

210 thick triangle-shaped vacancy platelets can directly produce <c> dislocation loops.

211 to infer the phenotypes of biospecimens not directly profiled.

212 We showed that TSLP can directly promote T(H)2-cell differentiation in the lung,

213 und that neurons isolated from mice with DED directly promoted VEC proliferation and tube formation c

214 cornerstones of synthetic strategies, which directly provides the direct molecular-based design of f

215 quality of board oversight could be measured directly, rather than relying on the heuristic of board

216 e, and the ability of nanopore sequencing to directly read DNA modifications.

217 by H3K4 di-methylation, histone sumoylation directly recruits the Set3 complex to both protein-codin

218 Our data suggest that suppression of RA directly reduces arrhythmia susceptibility and reinforce

219 ighly structured differential cross sections directly reflect the increasing number of contributing w

220 AL is shown to form a DNA-RNA triplex and to directly regulate BRCA1 transcription, thereby increasin

221 We have previously shown that primary cilia directly regulate insulin secretion.

222 we show that keratin intermediate filaments directly regulate the morphogenesis of microridges, elon

223 Directly regulated targets reflect the role of ABI3 in s

224 We find that Neurog1 directly regulates cxcr4b through an E-box cluster locat

225 To determine if the receptor directly regulates pendrin, as well as the effect of ser

226 Genomic analyses revealed that Hnf4a directly regulates the expression of genes involved in t

227 Whether this receptor directly regulates the intercalated cell chloride/bicarb

228 itro and in vivo and has a noncanonical role directly regulating actin dynamics.

229 Furthermore, we directly relate the experimentally observed yield of ful

230 n during low-temperature serpentinization is directly related to a Si deficiency in the serpentine st

231 The prevalence of introduced interactions is directly related to human environmental modifications an

232 breakdown of short-wavelength TA phonons is directly related to the Ag diffusion, with the vibration

233 to the size, the UHI intensity of a city is directly related to the density and an amplifying effect

234 uded activity in primary sensory regions not directly relevant to the task (e.g., neural activity in

235 es such as voicing periodicity, that are not directly relevant to the word recognition task.

236 ymal transition transcription factor SLUG to directly repress pro-apoptotic BMF, limiting drug-induce

237 Bcl-6 directly repressed Hhex in GC B cells.

238 ranscription factor FRUITFULL induces GPA by directly repressing genes of the APETALA2 (AP2) clade.

239 rowth has been hampered by the difficulty in directly sampling the small intestinal mucosa and microb

240 volves multiple laborious steps that are not directly scalable to current manufacturing platforms.

241 Ge(16) ](4-) and [Cd(6) Ge(16) ](4-) , were directly self-assembled through highly-charged [Ge(4) ](

242 A two-component system CpxRA directly senses acidification through protonation of Cpx

243 Here we directly set national PM(2.5) mortality cost reduction t

244 MutSgamma directly stimulates DNA cleavage by the MutLgamma endonu

245 is the only bona fide elongation factor that directly stimulates transcription elongation by RNA poly

246 nce that some of these 1T(1T') phases can be directly synthesized via bottom-up vapour- and liquid-ph

247 The compounds are shown to directly target tau pre-mRNA in cells, via chemical cros

248 They are directly targeted by some therapies, and the composition

249 se reporter assay confirmed that miR-466o-3p directly targeted WT1 mRNA.

250 thologically inspired behavioral paradigm to directly test the hypothesis that echolocating bats buil

251 In response, we directly test the original methods in a multinational st

252 hnical limitations, they have been unable to directly test the stress-reactivity hypothesis in situ.

253 To directly test whether such "special reservoirs" of zoono

254 However, this mechanism has not been directly tested in experiments.

255 cally microtubule-associated Pavarotti binds directly to actin in vitro and in vivo and has a noncano

256 baseline QTc levels and leukocyte count and directly to basal heart rates(p<0.01).At multivariate st

257 SPRED1 binds directly to both c-KIT and to the RasGAP, neurofibromin,

258 rabidopsis CenH3 in dividing cells and binds directly to both the N-terminal tail and the histone fol

259 argeted treatment approach to deliver toxins directly to cancer cells are one of the fastest growing

260 y indicate that these electrodes can be used directly to determine the unbound acetaminophen fraction

261 ay scattering, and microscopy can be related directly to device degradation and are attributed to the

262 logy search benchmarks, where we can compare directly to exact alignment methods that capture nested

263 or EpiSCs, formative stem (FS) cells respond directly to germ cell induction.

264 In KTA recipients, graft quality correlates directly to graft survival.

265 However, whether the virus spread directly to humans or through an intermediate host is cu

266 hromatin immunoprecipitation that MftR binds directly to malR.

267 s of the yeast ribosome and that it is bound directly to RNA molecules.

268 We scale ALT amounts in virtual mice directly to target plasma ALT values in individual mice.

269 e an alternate trafficking route delivers it directly to the autophagosomes.

270 cal propensity and establishes that H2 binds directly to the coiled-coil 1B (CC1B) domain of p150(Glu

271 ic silylene c-(CH)(2) (NtBu)(2) Si: proceeds directly to the corresponding tetrasilacyclobutene witho

272 Here, we demonstrate that BRI1 binds directly to the medium AP-2 subunit (AP2M).

273 y sensory neurons (OSNs) project their axons directly to the olfactory bulb (OB) glomeruli, where the

274 metabolomics generate data that relate more directly to the pathological symptoms and clinical param

275 we report that the oncoprotein Mdm2 can bind directly to the tumor suppressor VHL, and conjugate nedd

276 nditions were used to create monoliths bound directly to the walls of the titanium channels.

277 many of Sung Wan's early efforts contributed directly to Utah's biomaterials efforts and the Total Ar

278 iology, however not all of this knowledge is directly transferrable to cereals.

279 However, these advances have not directly transferred to metagenomic data sets, as assump

280 show that those different binding properties directly translate to distinct biological functions: fre

281 Some directly transmitted human pathogens, such as influenza

282 but that reduction in mTOR activity may not directly underpin Ag-expTh1 cell loss and exhaustion dur

283 the positive persons, 7292 were hospitalized directly upon presentation; an additional 882 persons te

284 Thus, XBP-1s may directly upregulate KSHV ORF21 and, thus, contribute to

285 gh expression of ABCE1, a translation factor directly upregulated by N-MYC, is itself a strong predic

286 we show that ligand activation of PPARalpha directly upregulates the long non-coding RNA gene Gm1544

287 addressed; MS signal intensities are usually directly used to calculate fold changes for quantitative

288 g that conventional fold-change calculations directly using MS signal intensities can be misleading.

289 Obstruction ought to be measured directly, using as the primary probe the DNA-binding spe

290 r, which interacts with a closed pore domain directly via two interfaces and indirectly via an interc

291 r characterize lesion recognition by ATL and directly visualize DNA lesion search by highly motile AT

292 The SECCM imaging directly visualized the relationship of HER activity and

293 n a liquid metal and a liquid electrolyte is directly visualized via advanced 3D chemical analysis.

294 gside optical microscopy techniques aimed at directly visualizing phase partitioning.

295 Multiple factors associate directly with CMG, including Ctf4 and the heterotrimeric

296 ere we demonstrate that human Sox2 interacts directly with one of these lncRNAs with high affinity th

297 only combinations of traits associated more directly with plant functional processes, rather than mo

298 Dosage and regimen parameters correlated directly with resulting fluid volumes.

299 oad range, with symptom severity correlating directly with virus-specific antibody magnitude.

300 that reduce firing rates and can be accessed directly without cued retrieval.