ライフサイエンスコーパス: disclose

1 The remaining authors have nothing to disclose.

2 hotophysical, and electronic attributes were disclosed.

3 tion, JUP: c.201delC; p.Ser68Alafs(*)92, was disclosed.

4 rus-Sulfur Incorporation reagents previously disclosed.

5 oups attached to the adamantane scaffold are disclosed.

6 s with CO(2) (1 bar) via 1,4-Ni migration is disclosed.

7 disubstituted, and trisubstituted alkenes is disclosed.

8 cy of the previously designed scaffold 1 was disclosed.

9 oles on improvement of antiviral activity is disclosed.

10 dopamine D(1) receptor (D(1)R) was recently disclosed.

11 ophiles to alpha,beta-unsaturated ketones is disclosed.

12 aring a Z-trisubstituted alkenyl fluoride is disclosed.

13 tracellular GC signaling in adipogenesis are disclosed.

14 ols containing acyclic quaternary centers is disclosed.

15 d asymmetric allylic trifluoromethylation is disclosed.

16 the catalysis of a cobalt salt under air is disclosed.

17 stereomeric dihydroxylation of cis-enynes is disclosed.

18 polycyclic norditerpenoid ineleganolide are disclosed.

19 dium-catalyzed conjugate addition pathway is disclosed.

20 and results from these trials are now being disclosed.

21 ve route to access these natural products is disclosed.

22 atives with 4-hydroxy-2-alkynoates have been disclosed.

23 he norcembranoid diterpenoid scabrolide A is disclosed.

24 to the C7-C22 subunit of amphidinolide K are disclosed.

25 d chiral dinitrogen ligands that we recently disclosed.

26 ing of the resulting haloarene in one-pot is disclosed.

27 wo new examples of in cellulo KTGS were also disclosed.

28 ivatives with both aryl and alkyl halides is disclosed.

29 available aryl ketones and alkynes has been disclosed.

30 that contain an alpha-stereogenic center is disclosed.

31 te addition to dehydroalanine derivatives is disclosed.

32 es mediated by selenium dioxide (SeO(2)) are disclosed.

33 n amidating reagent under mild conditions is disclosed.

34 scade hydroalkylation of 1,7-enynes has been disclosed.

35 methine substituted dihydropyrroles has been disclosed.

36 cokinetic data of these natural products are disclosed.

37 nter and a versatile alkenylboronic ester is disclosed.

38 g a quaternary carbon and an alkenylboron is disclosed.

39 We disclose a basal level of adult neurogenic activity char

40 Here we disclose a bioinspired strain-driven ring opening of bic

41 Here, we disclose a broadly applicable enantioselective [2 + 2]-c

42 Here we disclose a cascade strategy for naphthyne formation that

43 These results disclose a catalytic activity-independent growth-promoti

44 We herein disclose a computational study on the homo- and heterodi

45 opulation-level dynamic causal modelling can disclose a core pathophysiological feature of proteinopa

46 Herein we disclose a desymmetrization that employs phosphinic acid

47 In this work, we disclose a general method for the synthesis of BCP-conta

48 Moreover, our findings disclose a logic of Tmc use where hearing depends on a c

49 Herein, we disclose a method for its formation by intramolecular cy

50 Here, we disclose a method for the union of N-alkylamines and tri

51 Here, we disclose a mild method for the fluorine-18 ((18)F)-fluor

52 We disclose a Ni-catalyzed vicinal difunctionalization of a

53 We disclose a nickel/Bronsted acid-catalyzed tandem process

54 In this work, we disclose a non-invasive method for the monitoring and pr

55 We disclose a novel class of 6-amino-tetrahydroquinazoline

56 Altogether, these findings disclose a novel molecular mechanism for the maintenance

57 We disclose a novel radical strategy for the fluorination o

58 Here, we disclose a photoredox protocol for the replacement of a

59 Here, we disclose a porous, robust homochiral metal-organic frame

60 nd glutamatergic neurotransmission in PD and disclose a possible direct influence of D-amino acids va

61 In this manuscript, we disclose a powerful automated flow-based strategy for id

62 Our data disclose a previously unidentified functional interactio

63 Here, we disclose a series of supramolecular (co)polymers based o

64 To expand this field, we herein disclose a step-economical and temperature tunable strat

65 We disclose a study on nucleoside triphosphate (NTP) analog

66 Herein we disclose a three-component strategy to access quaternary

67 Cross-sectional imaging disclosed a 5.2-cm intraparotid mass and extensive adeno

68 Intraoperative exploration disclosed a big mass of hard texture involving the gallb

69 It also disclosed a carboxyl-terminal extension that forms a hel

70 Speakers who disclosed a COI were significantly more likely to give a

71 ed a COI disclosure statement and 41 (47.7%) disclosed a COI.

72 is conformation occurs in solution, but also disclosed a difference in kinetics when compared with KR

73 Cell transfection studies disclosed a dual behavior of R406W-desmin with both its

74 Previous studies disclosed a geographical pattern in the distribution of

75 Neuropathology disclosed a high percentage of macrophages linked to sub

76 (depleted in SER/THR PROTEIN KINASE8 [STN8]) disclosed a moss-specific pattern of thylakoid protein p

77 In addition, we disclosed a new approach towards the metal-free fluorina

78 ession and activity at the kinetochores, and disclosed a new in vivo function for USEs in Drosophila

79 irmed recurrent carcinoma, and staging scans disclosed a pulmonary metastasis.

80 Applying feature-reduction methods disclosed a set of metabolic pathways whose presence and

81 RNA-Seq analysis of F01D4.5 mutant worms disclosed a significant reduction in the expression of s

82 Serum tumor marker testing disclosed a slightly elevated alpha-fetoprotein (AFP) of

83 egative-stain EM with full-length antibodies disclosed a stable, ring-like antigen-antibody structure

84 Statistical analysis disclosed a stochastic deterministic relationship betwee

85 FMN release in machine perfusates of livers disclosed a strong correlation with lactate clearance an

86 ed ETS1 mutants, the molecular dynamics data disclosed a triad of residues that respond specifically

87 Our study discloses a chemically distinct apoptosis-targeting ther

88 This work discloses a continuous flow carbonylation reaction using

89 This leverage effect discloses a highly efficient route towards the ultrafast

90 ghly resistant to lethality in these models, disclosing a complementary, but independent role of casp

91 crystal structure of the ArnB paralog vWA2, disclosing a complex topology comprising the vWA domain,

92 a microkinetic model for ORR on Fe-N-C SACs, disclosing a self-adjusting mechanism induced by its int

93 practice, and recognising, responding to and disclosing adverse events, including errors and near mis

94 linical guideline or guidance statement must disclose all financial and intellectual interests relate

95 Clinical Guidelines Committee (CGC) aims to disclose all health care-related interests and manage co

96 This paper discloses also details on the synthesis of building bloc

97 Here we disclose an efficacious hybrid molecule 4-(5-Amino-1,2,3

98 In this Communication, we disclose an iron-based catalytic system for the function

99 he phosphomimetic mutant cocrystal structure disclosed an alternative arrangement in which the activa

100 The model disclosed an elongated complex containing a flexible hin

101 Statistical analysis disclosed an overall observed agreement of 93.4% among t

102 ling the exhaustion level of the person, and discloses an entirely novel approach to studying human d

103 cope of Cr-mediated carbonyl alkylations and discloses an underexplored retrosynthetic strategy for t

104 Disclosing an unrecognized metabolic hijack of macrophag

105 tent difluorinated probe with MMP-9 are also disclosed and indicate that the structural basis of inhi

106 AFFF composition is seldom disclosed, and their use elicits concerns from both regu

107 to support our mechanistic understanding is disclosed, and we now preclude the suggested involvement

108 This envelope protein does not disclose any fusogenic activity in ex vivo assays, at va

109 Comparative transcriptomic analyses disclose berry-specific upregulated expression in repres

110 imes more powerful than existing methods and disclose biological discoveries that otherwise cannot be

111 el in complex with a nanobody fusion-protein disclosing bound K(+) ions.

112 In contrast to (18)F-FDG PET, immuno-PET disclosed brain metastases.

113 N(x) centers in the carbon matrix is clearly disclosed by aberration-corrected scanning transmission

114 key role of the hydride ligand in 1 has been disclosed by both experimental results and DFT calculati

115 rtially originating from charge transfer, as disclosed by our energy decomposition analysis based on

116 ut also acts to alleviate RGO aggregation as disclosed by scanning electron microscopy, most likely d

117 ple tumors and anticipate that the molecules disclosed can be used as starting points for future effo

118 is in situ proteomics approach to a recently disclosed cancer-associated histone mutation, H3K4M, rev

119 ametric Mapping analysis (as a reference) to disclose cerebral metabolic patterns associated with con

120 The disclosed chemical probes are useful to identify other c

121 capacity for halogenation of two frequently disclosed compounds with demonstrated halogenation pathw

122 erein, we report application of a previously disclosed cyclic carbamate P1 linker which provided impr

123 of Adverse Outcomes in Heart Failure) trial disclosed DAPA's benefits in symptomatic heart failure,

124 The structural studies disclosed defective ribosome complex formation due to a

125 We have recently disclosed [(dtbpy)(2)RuCl(2)] as an effective precatalys

126 coupling of catharanthine with vindoline is disclosed, enlisting tris(4-bromophenyl)aminium hexachlo

127 olution: flash frozen toluene solutions of 1 disclose entirely different EPR spectra at 10 K when pre

128 s database (OP) have been compared with self-disclosed financial relationships made by physician auth

129 anding may be used to rationalize previously disclosed findings, significantly improve a transformati

130 s for 3) are remarkable and the highest ever disclosed for any DLC-based organic semiconductor, promi

131 This is disclosed for the C-H bond alkylation of biologically re

132 yclic carbenes (NHCs) and chiral diamines is disclosed for the first time.

133 not only offers clues for basic research to disclose genetics behind these agronomic traits, but als

134 f 11a bound to influenza A PB2 cap region is disclosed here and deposited to the PDB.

135 potential use in treating HCV infections is disclosed here.

136 Disclosed herein is the development of a novel single-el

137 The results disclosed herein lay the foundation for a clear interpre

138 zothiazine) scaffold of red hair pigments is disclosed herein.

139 es with ease of fabrication and operation is disclosed herein.

140 these catalysts in patent literature is also disclosed highlighting the versatility of the catalytic

141 two intramolecularly pai-stacked dimers and disclose how intramolecular stacking modes dictate photo

142 linear free energy relationships (LFER), we disclose how the formation of either imines or enamines

143 Structural characterization disclosed how the newly identified RBD mutations coopera

144 ng and the architecture of the active sites, disclosing important structural information for rational

145 view of the famed solid solution model first disclosed in 1959.

146 , specific pathogenic variants have not been disclosed in many individual patients when analyzed by n

147 ilar stereoelectronic interactions have been disclosed in other molecular structures, its presence in

148 ncept, and many 3d-metal catalysts have been disclosed in recent years.

149 for publication, what manipulations must be disclosed in the methods and the figure legends, and wha

150 mple of chiral molecular recognition and can disclose innovative approaches to enantioselective sensi

151 ools, but again these are often based on non-disclosed insurance data.

152 s the attributes and limitations of recently disclosed investigational drugs targeting Na(V)1.7 and r

153 Disclosed is a five-step synthesis of (+/-)-vibralactone

154 in ion suppression across the tissue, which disclosed itself as varying slopes in the per-pixel regr

155 Our findings disclose key behavioral and acoustic mechanisms enabling

156 tly resulting in the C481S substitution, and disclosed many mutations in PLCG2, encoding phospholipas

157 (57) Fe Mossbauer study discloses metal oxidation states of W(IV) (2) Fe(II) (4)

158 The disclosed method is amenable to a range of differentiall

159 The disclosed methods apply to other fluids or tissues provi

160 Taken together, these studies have disclosed mitochondria-dependent effects of cationic Au-

161 ith Notch signaling as the key regulator, we disclose molecular proof and lineage tracing evidence sh

162 nd spectroscopic/diffractometric studies, we disclose new gamma-/beta-turn and loop structures presen

163 Our findings disclose new opportunities to probe the causal roles of

164 The recently disclosed next generation of reversible, selective, and

165 RNA sequencing analysis disclosed no consistent differences in expression of ind

166 le thermophoresis of the dimerization domain disclosed no further assembly, but did reveal reversible

167 However, control Doppler US disclosed no ischaemia and successful exclusion of the a

168 of immunofluorescence retina nuclear layers disclosed no significant differences between TT and any

169 and multiangle light-scattering experiments disclosed novel oligomeric states of the LCP enzymes.

170 Herein, we disclose our efforts to identify potent, selective, and

171 s ownership in OP, but 35 authors/presenters disclosed ownership (including stock) to ASCO.

172 , and mapping of geographical origin without disclosing personal genomes.

173 UPLC-DAD-ESI-MS/MS analyses disclosed phenolic acids and tannins as constituents, in

174 g flow cytometry provides powerful means for disclosing population-based morphological membrane trans

175 mplicity, scalability, and tunability of the disclosed precursor platform are anticipated to inspire

176 In asymptomatic carriers, qAF disclosed previously undetected visual cycle deficiency.

177 ocument patient prognosis are more likely to disclose prognosis and offer comfort-focused care.

178 Documenting prognosis may help intensivists disclose prognosis to ICU proxies, but in isolation, it

179 We also disclose queen toots and quacks, showing statistics of t

180 Moreover, we disclosed reciprocal LDTg connections with structures in

181 agln2 using the adipocyte protein 2 promoter disclosed remarkable sex-dependent variations, in which

182 Secondary outcomes included disclosing risk of death.

183 Analysis of site occupancy data disclosed several new classes of STT3A-dependent accepto

184 erosexual and queer older people tend not to disclose sexual concerns and difficulties which increase

185 Quantitative OCT measurement disclosed significant distortions of both retinal thickn

186 f eIF3 subunits associated with the HCV IRES disclosed similar effects and that the a subunit is crit

187 pattern of altered neural activity has been disclosed so far.

188 ferentiation of human FOXP3(+) iTregs and to disclose some of the molecular pathways involved.

189 Our results disclosed statistically significant negative correlation

190 We disclose strategies for designing and synthesising frame

191 bstituted divinyl ketones using our recently disclosed strong and confined imidodiphosphorimidate Bro

192 peptidic inhibitors of CK2 subunit interface disclosing substrate-selective functional effects.

193 e core of ineleganolide, which was the first disclosed synthesis of the core of the norditerpene natu

194 Importantly, she had disclosed taking complex regiments of natural health pro

195 strated Lewis pairs have been uncovered that disclose that certain combinations of Lewis acids and ba

196 dies under CO(2), (13)CO(2), and CO with DFT disclosed that 1((I)) reacts with CO(2) to form the pivo

197 Importantly, these simulations also disclosed that a major conformational change occurs in t

198 The data disclosed that a single P2 layer is inserted between two

199 The structure disclosed that AFF4-CHD folds into a novel domain that c

200 cal microscopy studies and cell-based assays disclosed that after roseltide rT7 penetrates cells, it

201 The comparison disclosed that although both peptides are interfacially

202 The structures disclosed that although catalytic residues are conserved

203 The structures disclosed that although the structure in complex with AM

204 Mutational analyses disclosed that amino acids substitutions at the 246 and

205 Furthermore, functional assays disclosed that ATF3 is necessary and sufficient for HSF1

206 ed four strictly conserved GH26 residues and disclosed that BoMan26A and BoMan26B reside on two disti

207 Our experiments also disclosed that casein kinase 2 plays an integral role in

208 The structure disclosed that certain differences in the amino acid com

209 These structures disclosed that differences around the p7 residue subtly

210 disease process, genetic modifiers have been disclosed that explain the phenotypic heterogeneity of P

211 In vitro analysis disclosed that ferredoxin (flavodoxin):NADP(+) oxidoredu

212 n kinase bound PI(4,5)P2, biochemical assays disclosed that focal adhesion kinase is preferentially a

213 anthine that participate in the reaction are disclosed that identify the key structural features requ

214 Kinetic analysis and structural studies disclosed that IE2 is a SUMO cis-E3 ligase.

215 Analytical ultracentrifugation disclosed that IgG2 is monomeric with a sedimentation co

216 We further disclosed that Importin 4 (IPO4) augmented the nuclear t

217 Further investigations disclosed that inhibition of the G(2)/M regulator cyclin

218 ical assays with membrane-reconstituted SDBC disclosed that it is a nonselective channel that has som

219 Overexpression and depletion experiments disclosed that l-PGDS partakes in Rab4 activation follow

220 Mechanistic experiments disclosed that leptin activates signal transducer and ac

221 The RET-nintedanib co-crystal structure disclosed that Leu-730 in RET engages in hydrophobic int

222 ranes of DT40 cells expressing only TbIP(3)R disclosed that luminal inorganic orthophosphate (P(i)) o

223 contrast, leakage of anionic lipid vesicles disclosed that membrane disruption is closely associated

224 Furthermore, molecular profiling disclosed that neurodegenerative-related gene pathways a

225 ntified compounds with increased potency and disclosed that NTZ's nitrothiazole ring is critical for

226 Receiver operating characteristic analysis disclosed that R(up) <66% predicted persistent PH after

227 says performed in the presence of trap dsDNA disclosed that RHA enhances the processivity of HIV-1 re

228 Phos-tag SDS-PAGE coupled with MS analysis disclosed that SnRK1 indeed phosphorylates AtCCT1 at Ser

229 genes in these cells of the two species and disclosed that SOX9 targets showed high similarity of ta

230 These analyses also disclosed that SYNPO binds the tandem WW domain polypept

231 We have previously disclosed that synthesis of calcium diazeniumdiolate sal

232 Analysis of available TFB2M structures disclosed that the C-tail engages in intramolecular inte

233 Binding studies disclosed that the competitive inhibitor isoeugenol is p

234 It was disclosed that the conjugate of the pentasaccharide anal

235 her individually or both replaced by alanine disclosed that the double substitution does not abrogate

236 The structure disclosed that the enzyme comprises four domains, includ

237 The structures disclosed that the high-affinity ligand N-acetyl-d-gluco

238 Isothermal titration calorimetry disclosed that the highest affinity peptides (K(D) of ~1

239 econstruction of glycan degradation cascades disclosed that the individual or combined activities of

240 Moreover, in-cell fluorescence spectroscopy disclosed that the intracellular environment slows down

241 perando X-ray absorption spectroscopy, it is disclosed that the isolated single atom ruthenium was ke

242 orthern blotting experiments with rifampicin disclosed that the regulation of yciF expression is, mos

243 tal structure of HDAC6 complexed with NR-160 disclosed that the steric complementarity of the bifurca

244 In vitro and in vivo RNA-binding assays disclosed that these glycoprotein mRNAs are targeted by

245 sus a binding pocket-deficient double mutant disclosed that this binding site modulates USP11's funct

246 of resting-state functional connectivity and discloses that frame-wise contributions vary across time

247 ns and the outcome of trajectory simulations discloses that molecular beam studies merged with dynami

248 with density functional theory calculations discloses that the etching of lattice Cl(-) serves as th

249 n properties in dependence of the stack size disclosing that the absorption features can be rationali

250 d derivatives in complex with the EphA2 LBD, disclosing that YSA targets the ephrin-binding pocket of

251 Our findings disclose the binding site of TbFPC4 on TbBILBO1-NTD, whi

252 rganic fluoride (IF) analysis was applied to disclose the chemical composition of 24 foams intended f

253 Herein, we disclose the combined NMR spectroscopic, single-crystal

254 Herein, we disclose the development of a modular approach toward 2,

255 Here, we disclose the development of highly subunit-selective imm

256 Herein, we disclose the discovery and preclinical characterization

257 e-genome analysis of WSUCF1 was performed to disclose the essential genes correlated with nucleotide

258 dentified and contacted ARRs by telephone to disclose the familial pathogenic variant and offer telep

259 We herein disclose the first report of a first-row transition meta

260 We also disclose the first use of this reagent as a source of ra

261 Our results disclose the human anterior hippocampus as a likely arbi

262 Our results disclose the mechanism by which cIAP1 RING dimer activat

263 Herein, we disclose the medicinal chemistry discovery and the early

264 of our furan-based candidates allowed us to disclose the most potent competitive inhibitor known to

265 We now disclose the optimization of these targeted covalent inh

266 We disclose the results of an investigation designed to gen

267 In summary, these results disclose the structural architecture of the free forms o

268 Herein we disclose the synthesis and full characterization of the

269 We disclose the synthesis and structural characterization o

270 Direct visualizations of magnetic structures disclose the unique dynamical feature of a BP as an atom

271 Herein, we disclose the use of polysulfide anions as visible light

272 c beads coated with dietary polysaccharides, disclosed the contributions of targeted species to fiber

273 Recent work has disclosed the critical role played by enamel peptides in

274 We previously disclosed the discovery of truncating adenomatous polypo

275 variants reconstituted into proteoliposomes disclosed the following: (i) all variants act as UDP-Glc

276 outcome, the X-ray crystallographic analysis discloses the consequences of adding two electrons to th

277 Removing both at the same time discloses the extent to which this regulatory mechanism

278 This study discloses the first examples that show the Wolff rearran

279 This article discloses the in vitro and cellular activity profiles of

280 This article discloses the profile of GSK046, also known as iBET-BD2,

281 This work clearly discloses the structure-property relationships that the

282 FADS3 as a Delta14Z LCB desaturase, thereby disclosing the last missing enzyme of the SL de novo syn

283 the bioconjugate fractographic peak allowed disclosing the mixture of the different species in the b

284 is study examines whether Catholic hospitals disclose their religious identity and health care practi

285 Patients prefer that physicians disclose their self-discovered medical errors, and discl

286 By disclosing these compounds, we hope to provide valuable

287 Herein, we disclose three structurally differentiated gamma-secreta

288 Our study characterizes the recently disclosed three calcium binding sites of FXIII-A concern

289 The tree discloses three types of NDs: the stem NDs with less tha

290 masked for group assignment, which was only disclosed to the neurosurgical staff at the time of oper

291 common actions they would take if IMED were disclosed to them.

292 Here we disclose two new chemical scaffolds that inhibit Notum e

293 Further in silico analysis disclosed two yet unknown cis-regulatory DNA elements in

294 lation, followed by aza-Michael addition, is disclosed using 2-aminobenzothiazoles and ortho-halo cin

295 on transient functional brain dynamics were disclosed using hidden Markov modeling of power envelope

296 We disclosed various 3'-UTR length variants of ABCC1, C2, a

297 Future studies may disclose whether several different pathways lead to Hg m

298 pha and C-7alpha androstanes were studied to disclose which position among them is more convenient to

299 ocedure for dehydrative ketal protections is disclosed, which serves as an alternative to the classic

300 bonylation protocol of vinyl arenes has been disclosed with the help of alpha-bromocarbonyls where ae