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1 coded by 8 exons of which three code for the discoidin domain.
2 by recombinant Mfge8 containing at least one discoidin domain.
3  direct interaction of collagen with the DDR discoidin domain.
4 elical collagen and was mediated by the DDR2 discoidin domain.
5 ing collagen for cellular uptake through its discoidin domains.
6 orresponding loops of functionally unrelated discoidin domains.
7 growth factor repeats, an RGD motif, and two discoidin domains.
8                Each subunit is composed of a discoidin domain and a small N-terminal (RS1) domain.
9                                          The discoidin domain and PTK core of DDR-2 were essential fo
10 s thrombospondin repeats, a collagen-binding discoidin domain, and a catalytically inactive metalloca
11 cid protein, retinoschisin, which contains a discoidin domain but is of unknown function.
12 to the polypeptide chain termini of the DDR2 discoidin domain constitutes the collagen recognition si
13 the stability and cell-surface expression of discoidin domain-containing receptor 2 (DDR2) in breast
14  lineage CSC(1) (CTSK(+) CSC) and a separate discoidin domain-containing receptor 2 (DDR2) lineage st
15  ligands for the previously orphan family of discoidin domain-containing receptor-like tyrosine kinas
16                                              Discoidin domain-containing receptors (DDRs) exhibit a u
17             Receptor tyrosine kinases of the discoidin domain family, DDR1 and DDR2, are activated by
18 y that used wild-type and mutant forms of RS discoidin domain glutathione S-transferase (GST) fusion
19                                          The discoidin domain has been identified in mammalian milk f
20  studies determined selective binding to the discoidin domain of CASPR2.
21 heir extracellular domains, and the isolated discoidin domain of DDR2 bound collagen I with high affi
22                             Furthermore, the discoidin domain of DDR2, but not of DDR1, was sufficien
23  To map the collagen binding site within the discoidin domain of DDR2, mutant constructs were created
24 ted to change the amino acid sequence in the discoidin domain of the retinoschisin protein.
25 odies in the CSF targeted the laminin G1 and discoidin domains of CASPR2 in all patients.
26                                Activation of discoidin domain receptor (DDR) 1 by collagen is reporte
27                                              Discoidin domain receptor (DDR) 1 is a receptor tyrosine
28 collagen receptors, alpha2beta1 integrin and discoidin domain receptor (DDR) 1.
29                                          The discoidin domain receptor (DDR) is a new class of recept
30 ified the conserved receptor tyrosine kinase Discoidin domain receptor (Ddr).
31                                          The discoidin domain receptor (DDR1) is characterized by a d
32  receptors on the tumor cells, including the discoidin domain receptor 1 (DDR1) and E-Cadherin (E-Cad
33                                              Discoidin domain receptor 1 (DDR1) belongs to a unique f
34 he expression of the novel collagen receptor discoidin domain receptor 1 (DDR1) by human MKs at both
35 ss, we identified a receptor tyrosine kinase discoidin domain receptor 1 (DDR1) expressed in granule
36                                              Discoidin domain receptor 1 (DDR1) is a collagen recepto
37                                              Discoidin domain receptor 1 (DDR1) is a collagen recepto
38                                              Discoidin domain receptor 1 (DDR1) is a collagen-activat
39                                              Discoidin domain receptor 1 (DDR1) is a key sensor of CO
40                                              Discoidin domain receptor 1 (DDR1) is a nonintegrin coll
41                                              Discoidin domain receptor 1 (DDR1) is a receptor tyrosin
42                                              Discoidin domain receptor 1 (DDR1) is a receptor tyrosin
43                                              Discoidin domain receptor 1 (DDR1) is a receptor tyrosin
44                                              Discoidin domain receptor 1 (DDR1) is a unique collagen-
45                                              Discoidin domain receptor 1 (DDR1) is a widely expressed
46                                          The discoidin domain receptor 1 (DDR1) is activated by colla
47 e also identified that the downregulation of discoidin domain receptor 1 (DDR1) is synthetically leth
48  simultaneous delivery of mRNA encoding anti-discoidin domain receptor 1 (DDR1) single-chain variable
49                            Here we show that discoidin domain receptor 1 (DDR1), a collagen receptor
50                           Here, we show that Discoidin Domain Receptor 1 (DDR1), a collagen receptor
51  RNAi sensitization screen, which identified discoidin domain receptor 1 (DDR1), a collagen-activated
52                  Significantly, knockdown of discoidin domain receptor 1 (DDR1), a collagen-binding p
53                  We previously reported that discoidin domain receptor 1 (DDR1), a nonintegrin collag
54 on of Wnt5a, but also the phosphorylation of discoidin domain receptor 1 (Ddr1), a receptor for colla
55 esumed progenitors of HRS cells, upregulates discoidin domain receptor 1 (DDR1), a receptor tyrosine
56 iated melanocyte localization, we identified discoidin domain receptor 1 (DDR1), a receptor tyrosine
57                                              Discoidin domain receptor 1 (DDR1), a receptor tyrosine
58 volving latent membrane protein 1 (LMP1) and discoidin domain receptor 1 (DDR1), which is activated b
59                     Whereas cCol I activates discoidin domain receptor 1 (DDR1)-NF-kappaB-p62-NRF2 si
60 moural hepatocytes and through activation of discoidin domain receptor 1 in established tumours.
61 Ruggeri et al that reports the importance of discoidin domain receptor 1 in tissue homeostasis in pan
62                                              Discoidin domain receptor 1 tyrosine kinase (DDR1) and t
63 lagen-binding receptor tyrosine kinase DDR1 (discoidin domain receptor 1) is a drug target for a wide
64                                        DDR1, discoidin domain receptor 1, belongs to a subfamily of t
65 mechanical cue is transduced sequentially by discoidin domain receptor 1, c-Jun N-terminal kinase 1,
66 ivation of collagen receptors, integrins and discoidin domain receptor 1, play a role in disease prop
67 vestigate the relationship between increased discoidin domain receptor 2 (DDR-2) expression and carti
68 d MMP-13, degraded type II collagen, and the discoidin domain receptor 2 (DDR-2) in knee joints.
69 nvestigate the role of the collagen receptor discoidin domain receptor 2 (DDR-2) in the pathogenesis
70 hat a majority of human melanoma overexpress discoidin domain receptor 2 (DDR2) after treatment.
71                 In this study, we identified discoidin domain receptor 2 (DDR2) as a crucial receptor
72 ion of the tyrosine-kinase collagen receptor discoidin domain receptor 2 (DDR2) has no impact on huma
73 llular domain (ECD) of the collagen receptor discoidin domain receptor 2 (DDR2) inhibits fibrillogene
74                                              Discoidin domain receptor 2 (DDR2) is a collagen-activat
75                                              Discoidin domain receptor 2 (DDR2) is a receptor tyrosin
76                                              Discoidin domain receptor 2 (DDR2) is a tyrosine kinase
77                                              Discoidin domain receptor 2 (DDR2) is an unusual recepto
78 et al demonstrate that the collagen receptor Discoidin domain receptor 2 (DDR2) promotes neutrophil c
79                  Increased expression of the discoidin domain receptor 2 (DDR2) results from its inte
80 ptomic and proteomic analyses, we identified discoidin domain receptor 2 (DDR2), a cell surface recep
81                                              Discoidin domain receptor 2 (DDR2), a collagen receptor
82                      The collagen receptors, discoidin domain receptor 2 (DDR2), a collagen-specific
83                                              Discoidin domain receptor 2 (DDR2), an understudied coll
84 lated proteins: von Willebrand factor (VWF), discoidin domain receptor 2 (DDR2), and the extracellula
85 ression of a cell surface collagen receptor, discoidin domain receptor 2 (DDR2), is increased in chon
86 e show that the fibrillar collagen receptor, Discoidin Domain Receptor 2 (DDR2), promotes collagen pr
87 2, or collagen deglycosylation that prevents discoidin domain receptor 2 activation allowed cells to
88 t involves activation of the tyrosine kinase discoidin domain receptor 2 and is independent of effect
89                                              Discoidin domain receptor 2 expression was unchanged, bu
90                             Mutations in the discoidin domain receptor 2 gene (DDR2), which encodes a
91 RNA and also used to determine the amount of discoidin domain receptor 2 mRNA in cardiac tissue.
92 c), thymocyte differentiation antigen 1, and discoidin domain receptor 2).
93 tin, procollagen I, fibronectin I, vimentin, discoidin domain receptor 2, and tenascin C, markers of
94 nase inhibitor genistein, down-regulation of discoidin domain receptor 2, or collagen deglycosylation
95                                              Discoidin domain receptor tyrosine kinase 1 induces stem
96                                        DDR1 (discoidin domain receptor tyrosine kinase 1) kinase s hi
97 -trisphosphate receptor, type 3 (ITPR3), and discoidin domain receptor tyrosine kinase 2 (DDR2).
98 taining, and up-regulated mRNA expression of discoidin domain receptor tyrosine kinase 2, fibronectin
99                                              Discoidin domain receptor tyrosine kinase, activated by
100 inkage, also activates the collagen receptor discoidin domain receptor-2 (DDR-2) in both the utse and
101 drocyte responses through receptors, such as discoidin domain receptor-2 and syndecan-4.
102 gen I activates fibroblast collagen receptor discoidin domain receptor-2, contributes significantly t
103 ed growth factor receptors (PDGFRs), and the discoidin domain receptor.
104  show that the TVC-specific collagen-binding Discoidin-domain receptor (Ddr) cooperates with Integrin
105                                              Discoidin domain receptors (DDR) 1 and 2 represent a fam
106                                              Discoidin domain receptors (DDR1 and DDR2) are receptor
107                                              Discoidin domain receptors (DDR1 and DDR2) are receptor
108                                              Discoidin domain receptors (DDR1 and DDR2) are the colla
109                                              Discoidin domain receptors (DDR1 and DDR2) are widely ex
110 have recently been identified as ligands for discoidin domain receptors (DDR1 and DDR2), generating a
111                                          The discoidin domain receptors (DDRs) are receptor tyrosine
112                                          The discoidin domain receptors (DDRs) are receptor tyrosine
113                                          The Discoidin Domain Receptors (DDRs) constitute a unique se
114                                  The role of Discoidin Domain Receptors (DDRs) is poorly understood i
115 study, we found that collagen binding by the discoidin domain receptors (DDRs) requires dimerization
116                                    The human discoidin domain receptors (DDRs), DDR1 and DDR2, are ex
117               The widely expressed mammalian discoidin domain receptors (DDRs), DDR1 and DDR2, are un
118                                          The discoidin domain receptors (DDRs), DDR1 and DDR2, form a
119                                              Discoidin domain receptors 1 and 2 (DDR1/2) play a centr
120                                          The discoidin domain receptors, DDR1 and DDR2, are nonintegr
121                                          The discoidin domain receptors, DDR1 and DDR2, are receptor
122   Collagens and their cognate receptors, the discoidin domain receptors, have a role in various steps
123 mino acid mutation and insertion in the ACLP discoidin domain regulates collagen binding and assembly
124 ecific secreted protein encoding a conserved discoidin domain sequence.
125              Here, we tested the role of the discoidin domain tyrosine kinase receptor 2 (DDR2), whic
126 ially adjacent surface loops within the DDR2 discoidin domain were found to be critically involved in

 
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