ライフサイエンスコーパス: discriminate against

1 h voxels selective for the other class being discriminated against.

2 because terrestrial photosynthesis strongly discriminates against (13)CO(2), whereas ocean uptake do

3 In addition, plants discriminated against (18) O and (2) H during water upta

4 guanine for PurR and the ability of PurR to discriminate against 2-oxopurines do not result from dir

5 ingle-subunit RNAPs, a conserved Tyr residue discriminates against 2'dNTPs, whereas selectivity mecha

6 nt growth strongly fractionates Tl isotopes, discriminating against (205)Tl as the plant matures.

7 the substrate base that may explain how TDG discriminates against 5hmC and 5mC.

8 has a low affinity to DNA and is not able to discriminate against a mispaired template:primer in the

9 y deoxyribozymes show great specificity, can discriminate against a small number of mutations in the

10 While several DNA polymerases discriminated against a d(tC-A) base pair only by factor

11 ment interferes with fundamental freedoms or discriminates against a suspect class.

12 perceived as violating fundamental rights or discriminating against a protected class-for example, ag

13 To discriminate against abundant competitors, the Nramp met

14 TraA variability alone is not sufficient to discriminate against all cells, as traA allele diversity

15 nanomolar affinity for a single hmC/mC CpG, discriminates against all 14 other modified CpG dyads, a

16 eady-state kinetic analysis reveals that A3A discriminates against all ox-mCs by >3700-fold, arguing

17 r results also suggest that the MAT does not discriminate against alpha-substituted acyl-CoA thioeste

18 dant interactions and enhance specificity by discriminating against alternate sites.

19 It discriminates against aminoacyl transfer RNAs that do no

20 ut how RelA recognizes stalled ribosomes and discriminates against aminoacylated tRNAs is missing.

21 signals target analytes but also stringently discriminates against analogous competing analytes.

22 ide specificity for the transition state and discriminate against analogs that are larger only by ten

23 ome is the fact that unattractive people are discriminated against, and that such discrimination nega

24 Past research shows that decision-makers discriminate against applicants with career breaks.

25 Also, high-pass filtering discriminated against ascorbic acid, DOPAC, and acidic p

26 odified or Prp24-bound U6 snRNAs in order to discriminate against association with other RNAs.

27 th the P3 residue emerged, Kex2 was found to discriminate against at least one residue Asp. at this p

28 les mammalian 43S preinitiation complexes to discriminate against AUG codons with a context that devi

29 triplets, but it was unknown whether it also discriminates against AUGs in suboptimal context.

30 tion, and can be individually identified and discriminated against background scatter.

31 interaction of the aldehyde is critical for discriminating against BAL in some plant ALDH10s.

32 In addition to discriminating against base pair mismatches, DNA polymer

33 ting cGMP, as well as negative elements that discriminate against binding of cAMP, and that the cGMP/

34 he substitutions, A116W and N144'W, strongly discriminated against binding of GPP to the allylic site

35 Molecular modeling studies suggest how DGL discriminates against binding the biantennary complex ca

36 any state and local medical societies openly discriminated against black physicians, barring them fro

37 so demonstrate that the capacity of EF-Tu to discriminate against both of these aminoacyl-tRNAs is co

38 the target protein with a K(d) of 21 nM and discriminates against both the nonacetylated protein and

39 ctive site-binding groups in MDH effectively discriminates against both the shorter and the longer ke

40 lacking conical cells have been shown to be discriminated against by foraging bumblebees.

41 atient had been treated unfairly or had been discriminated against by health services.

42 with other rarely used initiation codons, is discriminated against by IF-3, resulting in the aborting

43 ackaging signal from phage Qbeta known to be discriminated against by MS2 coat protein both in vivo a

44 73.5%] vs 131 [57.2%], P = .006) and "I feel discriminated against by others" (12 [12.2%] vs 6 [2.6%]

45 ivity mechanism that accommodates G or U but discriminates against C and A bases.

46 two sites: one site favors Mg2+ and Ba2+ and discriminates against Ca2+, while the other site favors

47 Since this waveform effectively discriminates against capacitance currents, cyclic squar

48 ome, untargeted metabolomics will inevitably discriminate against certain compound classes.

49 racteristic of the folded protein target can discriminate against chemically similar species.

50 igators that the NIH peer review process may discriminate against clinical research.

51 evidence indicating that this conserved RNA discriminates against closely related analogues of Moco.

52 e genome are taken into account, in order to discriminate against commonly occurring patterns in the

53 ining set are taken into account in order to discriminate against commonly occurring signals and prod

54 soenergetic profiles for K(+) and Rb(+), and discriminates against Cs(+), all in agreement with exper

55 ir authentic substrates and regulators while discriminating against D-sites in other pathways.

56 That hpol eta discriminates against dATP exclusively at the insertion

57 RNA polymerases effectively discriminate against deoxyribonucleotides and specifical

58 This site discriminates against deoxyribonucleotides at the 3' end

59 ied as optimal films for PME by sufficiently discriminating against detrimental background current an

60 fer remarkable promise for cancer therapy by discriminating against devastating cytotoxicity of chemo

61 atically the ability of T7 DNA polymerase to discriminate against dideoxynucleotides.

62 cal G.C and A.T/U Watson-Crick base pairs to discriminate against DNA and RNA mismatches in order to

63 integrity of the genome, DNA ligase 1 (LIG1) discriminates against DNA junctions harboring mutagenic

64 ccur in populations that are marginalised or discriminated against due to structural, legal, and cult

65 cognize the initiation codon context, and to discriminate against establishing a codon-anticodon inte

66 insights into the mechanism MutM employs to discriminate against extrahelical normal DNA bases and i

67 GGTase-I discriminates against farnesyl diphosphate (FPP) at the

68 We find that bumblebees use color cues to discriminate against flowers that lack conical cells--bu

69 We also found that buff-tailed bumblebees discriminate against flowers with smaller bullseye sizes

70 the presence and quality of the other - bees discriminated against flowers with more defended pollen

71 e by over an order of magnitude and strongly discriminate against formation of non-native tertiary co

72 moieties of cAATrp, we demonstrate that CpaD discriminates against free Trp but accepts tryptophan-co

73 are both potent RT inhibitors, but Pol gamma discriminates against (-)-FTC-TP by two orders of magnit

74 ptors, unlike the C-X-C chemokine receptors, discriminate against Galpha16, a hematopoietic-specific

75 ting activity has evolved in this variant to discriminate against Glu.

76 other diseases and opens a rapid strategy to discriminate against health problems.

77 abidopsis thaliana accessions the ability to discriminate against heterospecific pollen.

78 petitive edge to ES, the species that better discriminated against heterospecifics.

79 possibility of future AI systems implicitly discriminating against humans as a class, giving AI agen

80 However, female D. heteroneura do not discriminate against hybrids on the basis of their head

81 come revealed that the surrogate having felt discriminated against in the healthcare setting was asso

82 ive binding by other analytes is effectively discriminated against in the mass-measurement step.

83 Remarkably, primase strongly discriminated against incorporating virtually all of the

84 t the hammerhead has an intrinsic ability to discriminate against incorrect bases, but emphasizes tha

85 er to further understand how DNA polymerases discriminate against incorrect dNTPs, we synthesized two

86 se analogues as compared to their ability to discriminate against incorrect natural dNTPs.

87 sis, DNA polymerases must rapidly sample and discriminate against incorrect nucleotides.

88 kinetics as well, which showed that T7 RNAP discriminates against incorrect NTP both at the nucleoti

89 RecQ does not reduce genomic instability by discriminating against incorrect D-loops.

90 sing DNA end-joining reactions that strongly discriminate against incorrectly paired DNA substrates.

91 ous studies have probed how effectively RecA discriminates against interactions involving a short sim

92 Instead, hPolbeta discriminates against L-stereochemistry through accumula

93 e.g. 4-phenylimidazole and morpholine) while discriminating against larger azole drugs.

94 binding pocket selective for fluoride, while discriminating against larger halide ions.

95 learn to recognize their own chicks and then discriminate against later-hatched parasitic chicks in t

96 site of USP11 as a contributing feature for discriminating against linear diubiquitin.

97 bias during the PCR amplification step that discriminates against longer homologs, as we show experi

98 L variant, supporting a model in which IFE-3 discriminates against m(3)(2,2,7)GTP by steric hindrance

99 Island females strongly discriminated against mainland males, suggesting that di

100 large body of research evidenced that people discriminate against members of their out versus ingroup

101 ften favor members of their own group, while discriminating against members of other groups.

102 Likewise, CDR3 alone did not discriminate against MHC binding, suggesting VDJ recombi

103 ants the nanogap sensor excellent ability to discriminate against mismatched sequences and allows hyb

104 rong, and the ability of each to effectively discriminate against mismatches in short duplex DNA.

105 step of strand exchange, the enzyme strongly discriminates against mismatches close to the cleavage s

106 t, whereas the Klenow fragment more strongly discriminates against mismatches, in accord with its gre

107 We demonstrate that MamM's CTD can discriminate against Mn(2+), supporting its postulated r

108 igid drug binding pocket that can be used to discriminate against molecules that are not substrates o

109 bacterium's biosynthetic machinery does not discriminate against monofluoro-fatty acid intermediates

110 4me3- over K4me2-containing H3 peptides, and discriminates against monomethylated and unmodified coun

111 nsing Watson-Crick base-pairing geometry and discriminating against near-cognate tRNA.

112 bute to the fidelity of protein synthesis by discriminating against near-cognate tRNAs on the ribosom

113 , we demonstrate that LIG1 is not capable of discriminating against nick DNA containing a 3'-ribonucl

114 ct the integrity of the tRNA molecule and to discriminate against nicked or damaged species from furt

115 d that eliminates sample to sample variance, discriminates against noise and artifacts, and improves

116 ent to bind all GU-rich sequences and yet to discriminate against non-GU-rich RNAs.

117 NA folding is that the free-energy landscape discriminate against non-native folds.

118 e site contacts that play essential roles in discriminating against non-substrates in the wild-type e

119 icity of the "native" protein-ligand complex discriminating against "non-native" binding modes and th

120 nslation, aminoacyl-tRNA synthetases (AARSs) discriminate against noncognate amino acids and cellular

121 ination, explaining the ability of LysRS1 to discriminate against noncognate substrates accepted by L

122 ficity toward the l-enantiomer of lysine and discriminated against noncognate amino acids with differ

123 NA synthetase (GlnRS) reveal that the enzyme discriminates against noncognate glutamate at multiple s

124 synthesis of 2'-5'/3'-5'-linked cGAMP while discriminating against noncognate NTPs and off-pathway i

125 te mRNAs for matched (cognate) targets while discriminating against noncognate targets.

126 When amoebae aggregate they do not perfectly discriminate against nonkin, leading to chimeric fruitin

127 us serve as identify barcodes to exquisitely discriminate against nonself to ensure populations are g

128 rahymena ribozyme to optimize its ability to discriminate against nonspecific substrates in vitro.

129 e, enable high-throughput screening, and can discriminate against nonspecific UAG decoding.

130 We have investigated how AAG discriminates against normal DNA bases, while accommodat

131 til (silk and ovary) a number of maize genes discriminate against or exclude pollen not carrying the

132 than the trimer and slightly less ability to discriminate against other DNA sequences.

133 tightly bind 8-oxoguanine (8-oxoG), strongly discriminate against other purine derivatives, and funct

134 ement to bind many GU-rich sequences and yet discriminate against other RNAs.

135 th an affinity of approximately 5 microM and discriminates against other sequences lacking the centra

136 V-associated pneumonia, although its role in discriminating against other respiratory viral-associate

137 mL depending on assay format) while strongly discriminating against other VLP types.

138 ts that, in fact, group-biased behavior that discriminates against out-groups is not inevitable after

139 How DNA polymerases discriminate against oxidized and undamaged nucleotides,

140 how the aptamer specifically selects p50 and discriminates against p65.

141 This indicates that F227A discriminates against particular base substitutions.

142 These practices structurally discriminate against patients of African and Middle East

143 eld study, egg-laying E. solidaginis females discriminated against plants previously exposed to the s

144 Pol alpha strongly discriminated against polymerizing dATP opposite 8-oxoG,

145 Although eIF1 autoregulates by discriminating against poor context in yeast and mammals

146 rm competition and female choice of sperm by discriminating against previous mates.

147 ggested to alter ribosomal fine structure to discriminate against prolyl-tRNA(Pro) and promote termin

148 Ps) contributes to C/EBPalpha specificity by discriminating against purines at position -3 and imposi

149 Nase T displays an unusual base specificity, discriminating against pyrimidine and, particularly, C r

150 Although most DNA polymerases discriminate against ribonucleotide triphosphaets (rNTPs

151 While most DNA polymerases discriminate against ribonucleotide triphosphate (rNTP)

152 approximately 1,000-fold-reduced ability to discriminate against ribonucleotides compared to that of

153 ratios, by the ability of DNA polymerases to discriminate against ribonucleotides, and by the capacit

154 Although DNA polymerases discriminate against ribonucleotides, many therapeutic n

155 da used a novel sugar selection mechanism to discriminate against ribonucleotides, whereby the ribose

156 , its active site has evolved the ability to discriminate against ribonucleotides.

157 dependent insertion represents a key step in discriminating against ribonucleotides because, once ins

158 subunits (R(CE)) of PKAI(CE) and stringently discriminates against RIIalpha and RIIbeta subunits, the

159 us of the AKAP helix, the hydrophobic groove discriminates against RIIalpha.

160 r lambda cro RNA but a much lower ability to discriminate against RNA molecules lacking cis-acting Rh

161 At amino acid 62, Phe discriminates against RNA binding and Tyr allows RNA bin

162 a monomer in a sequence-specific manner, and discriminates against RNA of telomeric sequence.

163 plays a high level of substrate specificity, discriminating against RNAs that contain a single base m

164 nsure genome stability, DNA polymerases must discriminate against rNTPs and incorporated ribonucleoti

165 sensitivities to ddNTPs and their ability to discriminate against rNTPs versus dNTP substrates on nat

166 s from several distinct families selectively discriminate against rUTP.

167 says, and confirmed that these RNAs strongly discriminate against SAM and other closely related analo

168 lity of cysteinyl-tRNA synthetase (CysRS) to discriminate against Sec.

169 ing domain, utilizes pre-transfer editing to discriminate against serine.

170 ive analysis of gene expression and does not discriminate against short or structured RNAs.

171 t determines specificity and how do proteins discriminate against similar ligands?

172 ides after 3-nitrotyrosine while effectively discriminating against similar peptides containing unmod

173 The enzyme must, however, also discriminate against smaller substrates, such as pyruvat

174 ersally detect any organic compound, it will discriminate against species with high molar absorptivit

175 ific RNAs, Rrp6p utilizes its selectivity to discriminate against specific RNAs.

176 substrate selectivity that enables Rrp6p to discriminate against specific RNAs.

177 s a litmus test for these FMS hallmarks that discriminates against spurious contributions from magnet

178 However, current methods frequently discriminate against structured and/or small RNA species

179 ic Tev-LHEs are active in vivo and similarly discriminate against substrates lacking the 5'-CNNNG-3'

180 transcriptase (RT) that allow the enzyme to discriminate against such analogs.

181 rties in the ability of CaM to recognize and discriminate against targets by tuning its conformationa

182 a lesion-bypass DNA polymerase) specifically discriminates against tC in the template strand may sugg

183 pair only by factors <10, T7 RNA polymerase discriminates against tC-A base pair formation by factor

184 in the template strand may suggest that DinB discriminates against template modifications in the majo

185 of aromatic residues, which is predicted to discriminate against the CoA thioesters.

186 may be common in the ocean but difficult to discriminate against the complex chemical background of

187 ucker and trans peptide bond, P4H appears to discriminate against the conformation of proline residue

188 These clusters were shown to discriminate against the development of angiographic CAV

189 imetic pheromone during mate search but must discriminate against the model cue to avoid orienting to

190 isplays asymmetry in terms of its ability to discriminate against the modification of the DNA templat

191 tics strongly suggests that SepRS is able to discriminate against the noncognate amino acids glutamat

192 Both mutants and the wild-type enzyme discriminated against the mismatched primer at the catal

193 PBP2a effectively discriminates against the beta-lactam antibiotics as pot

194 at the electrode surface while cytochrome c discriminates against the electrode surface.

195 However, how LIG1 discriminates against the mutagenic 3'-mismatches incorp

196 Also, RedJ strongly discriminates against the streptomycete ACP of fatty aci

197 with the dithiolane ring of lipoic acid and discriminating against the entry of biotin.

198 heterologous systems in a reciprocal manner, discriminating against the formation of initiation compl

199 beta-Glu(44) with alanine prevented IHF from discriminating against the H'44A variant but not the oth

200 join correctly base-paired substrates, while discriminating against the ligation of substrates contai

201 s for reading the isoleucine codon AUA while discriminating against the methionine codon AUG.

202 zyme plays an important role in catalysis by discriminating against the monoanionic form of substrate

203 osphorylation of Thr-38 while simultaneously discriminating against the phosphorylation of Ser-26 is

204 localizing with active methylation marks and discriminating against the repressive H3K27me3 mark.

205 e Asp133 of dCK that is most responsible for discriminating against the thymine base.

206 lary and a consistent set of gene signatures discriminating against the transcriptomic cell types and

207 ng reference chicks, coots can be induced to discriminate against their own offspring, confirming tha

208 w fragment exhibit a remarkable inability to discriminate against these analogues as compared to thei

209 Both EF-Tu orthologs discriminate against these misacylated tRNAs, confirming

210 By discriminating against these misacylated tRNAS, EF-Tu pl

211 n products suggests that the polymerases may discriminate against this pairing system on the basis of

212 However, Cre discriminates against this substrate both before and aft

213 lection yielded compact gene signatures that discriminated against tumor, normal, and mucosa.

214 pairing specificity, we have hypothesized to discriminate against U/G wobble pair by tailoring the st

215 nine (oxoG) to be correctly paired, while it discriminates against U-oxoG and G-oxoG mispairs.

216 identical to the native U/A base pair, while discriminating against U/G wobble pair.

217 , with apparent mid-nanomolar affinity while discriminating against uniform dsRNA.

218 nability of pol alpha and Klenow fragment to discriminate against unnatural bases.

219 ns greatly complement direct interactions in discriminating against various types of trap interaction

220 dy of work has shown that insect pollinators discriminate against white phenotypes when white flowers