ライフサイエンスコーパス: disengage

1 device (malreduced), and post-disengagement (disengaged).

2 olumns to constrict, and the gear network to disengage.

3 lassical ERalpha signaling is epigenetically disengaged.

4 mitosis or early G1 phase, when they become disengaged.

5 were less clearly defined when tracking was disengaged.

6 TJ- and AJ-integral membrane proteins can be disengaged.

7 nd leaves NF155 on apposing paranodal myelin disengaged.

8 ndodomain is truncated and cAMP induction is disengaged.

9 lly for groups who tend to be underserved or disengaged.

10 he application is stopped and the channel is disengaged.

11 0.05|1.51; p = 0.0128; 82%) of recovery when disengaged.

12 during 2013-2014 and outcomes for those who disengaged.

13 :UAF1 deubiquitinase only occurs when DNA is disengaged.

14 for transport (ESCRT) machinery is purposely disengaged.

15 sic endonuclease activity, which removes the disengaged 3' RNA segment.

16 nd July 31 2015 silently transferred or were disengaged (40% male, median age 35 years, median CD4 le

17 nd 31 July 2015 silently transferred or were disengaged (40% male; median age, 35 years; median CD4 l

18 clinical trials, or HER4 antagonists, which disengage 4ICD signaling, may have untoward activity in

19 tor output decays because the brain actively disengages a component of the memory.

20 edge of the matured phragmoplast were often disengaged, accompanied by conspicuous retentions of MAP

21 hat SSeCKS suppresses metastatic motility by disengaging activated Src and then inhibiting the PKC-Ra

22 ells usually do not fuse with each other but disengage after the viral particles have been delivered,

23 a targets a specific SAP97 splice variant to disengage AKAP79/150 from regulating GluR1 AMPARs, provi

24 a current choice, exploring alternatives or disengaging altogether.

25 mers when they are not bound to DNA and then disengage and are replaced by class II ERPs to form high

26 opose a model in which flagellar stators are disengaged and sequestered from the flagellar rotor when

27 during preprotein import, the Toc159G dimer disengages and the dimer interface contacts translocatin

28 ovince clinic within 180 days, 9,005 (22.6%) disengaged, and 28,069 (70.4%) remained in care.

29 and in the absence of nucleotides, the NBDs disengage asymmetrically while the conformation of the T

30 rget tissues or cells that can be engaged or disengaged at will is predicated on understanding the ne

31 HUs were slower to disengage attention, relative to their faster baseline o

32 hemineglect, and specifically difficulty in disengaging attention in tests of covert orienting.

33 ow that early bilingual adults are faster at disengaging attention to shift attention, and at noticin

34 This mechanism to disengage bacterial clearance from inflammation required

35 alone (imatinib) is not sufficient to fully disengage BCR-ABL-mediated signaling and suggests that B

36 e balance between engaged reward seeking and disengaged behavioral states remains unclear.

37 rs Axin's affinity for beta-catenin, thereby disengaging beta-catenin from the degradation machinery.

38 esolimbic dopaminergic system, and failed to disengage both the BLA and plasticity-related AMPA recep

39 Following ionizing radiation, cells with disengaged BRCA1-PALB2 interaction show greatly increase

40 Upon synaptic stimulation, CaMKII is disengaged by calcium-calmodulin, triggering network dis

41 he suppression of reward seeking and rapidly disengaged by opioids.

42 CA1 pyramidal neurons that can be engaged or disengaged by small shifts in net membrane current near

43 ng approach, we show that VTA DA neurons are disengaged by the PBN afferent activation, implicating t

44 going some type of cytoplasmic processing to disengage c27/25 mRNA and make it available for translat

45 arch by remodeling the splicing substrate to disengage candidate splice sites.

46 Mechanistically, Gb3 bound and disengaged CD19 from its chaperone CD81, permitting CD19

47 While most cells with disengaged centrioles maintain spindle bipolarity, clust

48 s maintain spindle bipolarity, clustering of disengaged centrioles requires the kinesin-14, HSET.

49 ing meiosis II, resulting in spermatids with disengaged centrioles.

50 nt on Cdk2/cyclin E, and requires previously disengaged centrioles.

51 Supporting disengaged children and young people living with diabete

52 all impact in the 1- to 13-J range, 10 (17%) disengaged completely from the orbital mount.

53 re sharply when the animal shut his eyes and disengaged completely from the task (5-10 minutes).

54 side chains within the lipid bilayer, and it disengages concomitant with substrate folding.

55 The disengaged condition resulted in average recovery of 1.7

56 ies down the key catalytic dynamic loop in a disengaged conformation and also locks the tetramer in a

57 e AMP complex) with active site loops in the disengaged conformation.

58 E(2) recruited ERalpha and disengaged corepressors from DACH1 at an endogenous ER r

59 Disengaged countertransference was associated with schiz

60 -risk group, which manifests as a failure to disengage default-mode regions in those at familial risk

61 Surprisingly, disengaging desmosomes from IF also accelerated the expr

62 In the DISENGAGE (Determination of Fractional Flow Reserve in I

63 cium-cAMP signaling during fatigue or stress disengage dlPFC recurrent circuits, reduce firing and im

64 ation, and hence was historically assumed to disengage during goal-directed tasks.

65 cognitive performance, rather than becoming disengaged during cognitive tasks.

66 mode network that is engaged during rest and disengaged during cognitive tasks.

67 somerization of allylic alcohols, whereas it disengages during the isomerization of alkenyl alcohols

68 hat enables flies to independently engage or disengage each wing from the mechanically linked thorax.

69 RvD4 disengaged emergency granulopoiesis, prevented excess BM

70 e no moving parts and animals can engage and disengage entirely at will.

71 One mechanism, direct suppression, disengages episodic retrieval through the systemic inhib

72 asured twice (with GC engaged [FFR(eng)] and disengaged [FFR(dis)]) in 202 intermediate stenoses of 1

73 the R-state, loop-engaged and T-state, loop-disengaged forms of FBPase.

74 ly, participants could freely decide when to disengage from a character and what to explore next.

75 whether participants could exert control and disengage from a memory state when it was no longer requ

76 This observation suggests that Eps15 may disengage from AP-2 during coat formation.

77 ver time will lead the agent to increasingly disengage from bodily responses even in the face of a le

78 are predisposed to readily integrate into or disengage from conserved genetic networks influencing or

79 individual's ability to both engage with and disengage from emotional stimuli.

80 s indicate that, on stress, ribosomes do not disengage from ER-associated transcripts (puromycin inse

81 CD phenotype, such as patients' inability to disengage from internally-generated scenarios and though

82 in the active site reveals that G1207 has to disengage from its Watson-Crick base pairing interaction

83 ars at the centrosome, procentrioles mature, disengage from mother centrioles, and ultimately duplica

84 k activity and micturition may allow time to disengage from ongoing behaviors unrelated to micturitio

85 these individuals had an impaired ability to disengage from opioid-related information.

86 Cdc6 and Orc1 progressively disengage from ORC as MCM translocates along DNA.

87 st in larger samples whether a difficulty to disengage from punishment avoidance contributes to chron

88 system), making it difficult for children to disengage from reward-seeking/consuming behaviors; and 3

89 al health(1-3) and can cause young people to disengage from stressful pursuits, resulting in missed o

90 These findings suggest that TonB does indeed disengage from the cytoplasmic membrane during energy tr

91 d default mode networks and the inability to disengage from the default mode network may be critical

92 result of the Cu(I)-CsoR mutants failing to disengage from the DNA targets, thus inhibiting the dere

93 r engages poorly processive polymerases that disengage from the DNA template prematurely.

94 ving systems that allow a driver to entirely disengage from the driving task also require the driver

95 sition and maturation, dendritic cells (DCs) disengage from the extracellular matrix, cross basement

96 and the failure of LPFC-lesioned animals to disengage from the immediately preceding response, it is

97 ger individuals, older adults failed to both disengage from the interruption and reestablish function

98 sult arises from our assumption that stators disengage from the motor for a significant portion of th

99 k codon-anticodon pairing allows the tRNA to disengage from the mRNA and slip +1, or an unusual codon

100 ack is necessary for the early-acting CRM to disengage from the promoter so that the late-acting CRM

101 e data showed that helices alpha1 and alpha6 disengage from the rest of the domain, leaving helices a

102 echanisms that rescue polymerases failing to disengage from the template at pA sites.

103 Epithelial cells disengage from their clusters and become motile by under

104 mbryos only start to incorporate Cnn as they disengage from their mothers; this generates a centrosom

105 rylated by src kinases when epithelial cells disengage from their tissue framework, identifying an im

106 " pauses, and that they can also temporarily disengage from these tracks, resulting in more prolonged

107 ifferentiated models of care before patients disengage from treatment programmes, increasing cost-eff

108 based on evidence that both an inability to disengage from unattainable goals and low interest in an

109 Inability to disengage from ZO-1 correlated with increased GJ plaque

110 efficiency, suggesting that the inability to disengage from ZO-1 prevented maturation of functional i

111 the tendency to enter into, and inability to disengage from, a negative mood state rather than the mo

112 eightened experience of, and an inability to disengage from, negative emotions in depressive disorder

113 s showed that when interrupted, older adults disengaged from a memory maintenance network and realloc

114 tion of the place code when mice voluntarily disengaged from a virtual navigation task, remarkably ev

115 public-sector ART programs in South Africa, disengaged from care at least once in a contemporary 2-y

116 and those of indigenous ethnicity) and those disengaged from care were more likely to remain HCV RNA

117 ts (PWID and Indigenous ethnicity) and those disengaged from care were more likely to remain HCV RNA

118 never referred and those who had previously disengaged from care.

119 time, health care delivery systems are often disengaged from clinical trials and fail to rapidly inco

120 ation, implying that astrocytes were largely disengaged from cortical input in healthy tissue.

121 (L3 AVs) can enable drivers to be completely disengaged from driving and safely perform other non-dri

122 e kinesin-14d1 mutant had kinetochore fibers disengaged from each other during mitosis and exhibited

123 apses between INs and PNs are engaged in and disengaged from functioning in a highly dynamic way acco

124 mplex, in which the mutant HisP subunits are disengaged from HisQ and HisM, suggesting that the resid

125 40-50% of individuals diagnosed with HIV are disengaged from HIV care.

126 We also provide evidence that NEMO is disengaged from IKK complex following genotoxic stress i

127 tabilized in an "intermediate" conformation, disengaged from important phosphoryl transfer residues.

128 n an open conformation, with its SNARE motif disengaged from its Habc domain and its linker region un

129 The phosphorylated regulatory domain is disengaged from its inhibitory position; the nucleotide-

130 /PFKFB3 signaling, this increases glycolysis disengaged from oxidative phosphorylation with mitochond

131 19 (6%) patients disengaged from services (12 [7%] of 165 CTOs vs 7 [4%]

132 tter is the most probable when the tandem is disengaged from the catalytic domain.

133 nvalid trials only, when attention had to be disengaged from the distractor and reoriented to the tar

134 e DMN is primarily a "task-negative" network disengaged from the external world.

135 e T2SS-ATPase complex is usually present but disengaged from the inner membrane, the T2SS has a much

136 Akt in which the PH domain is constitutively disengaged from the kinase domain are phosphorylated at

137 merular basement membrane and, occasionally, disengaged from the parietal basement membrane.

138 an alternative route of viral transmission, disengaged from the well-known extra-cytoplasmic ACE2 do

139 slation of Tnp1 and Tnp2 mRNAs is temporally disengaged from their transcription.

140 More participants in the VBP group disengaged from treatment, while VBP also had greater th

141 in the tendency for our attention to become disengaged from what we are reading.

142 n and clarify the fate of the toxin after it disengages from BiP.

143 SPEN rapidly disengages from chromatin upon gene silencing, suggestin

144 odel: When the tyrosine-phosphorylated STAT1 disengages from DNA, the ND dimerizes and somehow assist

145 he closed conformation of CD81, however, EC2 disengages from EC1 and rotates toward the membrane, the

146 ILY disengages from hCD59 during the prepore to pore transit

147 ATP-BiP disengages from NHK, enabling it to retrotranslocate to

148 D1 hydrolyzes ATP and disengages from substrate prior to D2, while D2 rebinds

149 Here we probed how BiP disengages from SV40 to enable the virus to penetrate th

150 n of the ternary complex in which the enzyme disengages from the 3' end of the transcript and moves b

151 We show that PolB1 repeatedly disengages from the DNA template, leaving PCNA123 behind

152 d base lesion or, in some cases, its partner disengages from the helix and is bound to the enzyme's a

153 When bound to MHCI, but not MHCII, Valpha disengages from the Jalpha beta strand, switching Valpha

154 depletion, the soluble catalytic V(1) sector disengages from the membrane integral V(o), and at the s

155 the assembly of the prepore oligomer, but it disengages from the receptor upon the conversion to the

156 und that the Pol III* subassembly frequently disengages from the replisome during DNA synthesis and e

157 Following mismatch detection, MutS disengages from the replisome, facilitating repair.

158 ng the transition, the transport domain (TD) disengages from the scaffold domain (SD), allowing it to

159 phenomenon when the 3' end of the transcript disengages from the template DNA.

160 We measured the efficiency of disengaging from a central visual stimulus to orient to

161 In particular, disengaging from coping efforts can signal the likelihoo

162 young people living with HIV are at risk of disengaging from HIV care at all stages of the care casc

163 TOs on readmissions and the risk of patients disengaging from mental health services temporarily or e

164 istory of NSSI, particularly a difficulty in disengaging from NSSI images.

165 duals with chronic worry may have difficulty disengaging from punishment avoidance when instructed to

166 depicts single protein molecules completely disengaging from the network.

167 ol group flexibly adjusted their behavior by disengaging from the newly ineffective action in favor o

168 releases transcripts 2-8 nt in length before disengaging from the promoter and isomerizing to a stabl

169 GAPDH, by engaging/disengaging glycolysis and through fluctuations in its e

170 Force required to disengage guide wires from filters was measured.

171 Almost all those currently disengaged had prior experience of treatment.

172 Here, we used a genetic approach to disengage HIF activation from EPO synthesis and found th

173 However, Asf1 was unable to disengage histones from DNA for tetrasomes formed with H

174 These macrophages disengage if cells normalize p21 within 4 days, but if p

175 nputs co-engage early in action learning and disengage in a dissociable manner as actions are refined

176 However, by 14 months, longer latencies to disengage in the subset of the risk group later diagnose

177 ltured cells and HDAC1 binding to the AR was disengaged in a DHT-dependent manner.

178 People currently engaged and disengaged in care are similar with respect to age and g

179 rate that both restraining mechanisms can be disengaged in heteromeric channels to form fast and sens

180 ot reward-dependent, cholinergic activity is disengaged in proficient animals when the task becomes r

181 dback loops of the plant circadian clock are disengaged in roots, because two key clock components, t

182 Hydrogen bonding is nearly completely disengaged in the E-dipyrrinone half; yet, the ridge-til

183 d adaptively to food scarcity are relatively disengaged in the setting of continuous food availabilit

184 ctivated in well-trained rats if they became disengaged in the task and in response to an unexpected

185 ment initiation, or lasted up to that point, disengaging in time for antagonist activation to interru

186 rocess, with parts of the brain engaging and disengaging in time.

187 direction of coherent motion, and a second, disengaged (inattentive) state, where performance drops

188 assium glutamate stimulates transcription by disengaging inhibitory polymerase interactions at a sigm

189 likely through VTA glutamatergic neurons, to disengage instrumental food-seeking behaviors.SIGNIFICAN

190 BN-to-VTA input during food reward retrieval disengages instrumental food-seeking behaviors but spare

191 ivity is required for successful invasion to disengage interactions between parasite adhesins and hos

192 cular shuttling of mLT-expressing MZ B cells disengaged interactions between these MZ B cells and LTb

193 When disengaged interactions within a receptor are turned on

194 in gene transcription, whereas deacetylation disengages it from the antioxidant response element, the

195 t with the hypothesis that photoexcited CRY2 disengages its C-terminal domain from the PHR domain to

196 zed that photoexcitation derepresses CRY2 by disengaging its C-terminal domain from the N-terminal PH

197 also demonstrate that TRAF2 interactions can disengage JNK signaling from NF-kappaB activation and th

198 SMC head interface, whereas the Wapl subunit disengages kleisin, but only after ATP rebinds.

199 l communities, households are uninformed and disengaged; leaders' authority is unchecked.

200 eraging the ability of our system to rapidly disengage ligand binding, we also measure slower reset r

201 teric inhibitor, which promotes the T-state, disengaged-loop conformation.

202 hat maternal presence blocked fear learning, disengaged mesolimbic circuitry, basolateral amygdala (B

203 hibits motility like a molecular clutch that disengages MotA.

204 Kampala: 5 with retained mothers and 3 with disengaged mothers from the PVT.

205 two in-depth interviews were conducted with disengaged mothers.

206 ining of a movement reshapes motor circuits, disengaging motor cortex potentially for automatized exe

207 in a manner similar to that of a clutch, by disengaging motor force-generating elements in cells emb

208 CFTR maturation pathway that is required to disengage nascent CFTR from ER biosynthetic machinery.

209 competitive binding of unconnected proteins disengages networks and prevents LLPS.

210 The E. coli Rho protein disengages newly transcribed RNA from its DNA template,

211 s that initially promote NHEJ and eventually disengage NHEJ.

212 such as feeling overwhelmed, burned out, or disengaged often remain hidden due to fear of judgment o

213 ated antiretroviral therapy and subsequently disengaged, often multiple times.

214 124I ensues, with the R-subunits transiently disengaging, on average, every 515 bp.

215 motors engaged in a tug-of-war resolvable by disengaging one motor species.

216 hat motors at a leading kinetochore abruptly disengage or turn off, leading to a direction reversal.

217 age, but not across individuals who socially disengage or who speak different languages.

218 ecursive intromission attempts when the male disengages or is dislodged from the hermaphrodite genita

219 tional regulators inhibit motility by either disengaging or jamming the stator-rotor interaction.

220 d demonstrate that its amino-terminal domain disengages p53 from Numb, triggering p53 proteolysis and

221 e a neuronal encoding scheme for how anxiety disengages PFC during decision making.

222 The template switch disengages Pol II from DNA and effectively terminates tr

223 e possible role of nucleolytic retraction in disengaging pol III from TFIIIB is discussed.

224 irst pollen tube alters ovular conditions to disengage pollen tube attraction and prevent the approac

225 au sequesters the polymerase tail from beta, disengaging polymerase from DNA.

226 ivity globally, reaching remote or otherwise disengaged populations.

227 sing its cognate sites, sumoylation fails to disengage prebound p53 from DNA.

228 large proportion of the myosin population to disengage rapidly from actin filaments.

229 This coordination engages and disengages rapidly in association with cognitive demands

230 Those who died or disengaged recently were previously distributed across a

231 strategies such as persevering, exploring or disengaging remain poorly understood.

232 cal violence because of random responding by disengaged respondents and because of a reliance on hypo

233 ngly, perturbation of the miR156/SPL9 module disengages seedling responsiveness to warm temperatures

234 ng Src to caveolin-rich lipid rafts, thereby disengaging Src from FAK-associated adhesion and signali

235 es of the ATPase motor, favoring a partially disengaged state of the ATPase motor on the nucleosome.

236 s blocks, achieving high performance even in disengaged states by biasing choices toward the side wit

237 low biases relative to the stimulus and two disengaged states with pronounced biases relative to the

238 greater past reward predicted transition to disengaged states, suggesting that disengagement may be

239 ds predicted transitions between engaged and disengaged states.

240 coupling, suggesting that 2-APB has to first disengage STIM1 before it can directly gate Orai3 channe

241 e catechin moiety, which recruits previously disengaged substituents into the binding interface and l

242 nction after the enzyme binds nucleosomes to disengage substrate histone tails from nucleosomal DNA.

243 k across the mitochondrial inner membrane to disengage substrate oxidation from ATP production.

244 Inhibition of the disengaged task remains active for a period of time and

245 the allocation of computational resources by disengaging task-irrelevant cortical regions.

246 "two-hit" mechanism in which tau acetylation disengages tau from MTs and also promotes tau aggregatio

247 Consequently, HIV-1 Nef disengages TCR triggering from the generation of p-LAT a

248 A2A adenosine receptors (A2AR) was shown to disengage the critical immunosuppressive mechanism and c

249 el the metastatic population, we are able to disengage the direct dependency of the metastatic burden

250 tion in adults), maternal presence failed to disengage the mesolimbic dopaminergic system, and failed

251 presence of operative cues (primes), novices disengage the prefrontal cortex and seem to accept the o

252 these changes in allowing the polymerase to disengage the promoter is poorly understood.

253 is movement is blocked the polymerase cannot disengage the promoter.

254 litated by nascent peptide interactions that disengage the ribosome anticodon-codon interactions for

255 ulate the rate at which complexes attempt to disengage the sigma(70):DNA interaction.

256 compressive force) caused the attachments to disengage the tip and slide over the filament, but slidi

257 The synthetic lesions (i) completely disengaged the premorbid system, leaving the alternative

258 rearrangement of the dimer interface, which disengages the agonist-induced conformational change in

259 ertion of lipoprotein acyl chains physically disengages the chaperone protein from the transporter by

260 recombination intermediates and in so doing disengages the D-loop structure by cleaving the 3'-invad

261 ction between the two proteins in which FEN1 disengages the Dna2 tracking mechanism.

262 eby swiveling around an alpha-helical linker disengages the His domain from the PEP-binding domain.

263 phosphorylation of human Pgp and mouse Pgp1a disengages the influence which these Pgps have on ICl(sw

264 that chronic impairment of local inhibition disengages the mPFC from its cognitive functions by part

265 sbA, envisions a large-amplitude motion that disengages the nucleotide-binding domains and repacks th

266 ion of the pause hairpin with RNA polymerase disengages the RNA 3' end from the active site.

267 Previously, we demonstrated that FEN1 disengages the tracking mechanism of Dna2 to remove it f

268 s intramolecular SUMOylation of TRIM28, thus disengages the TRIM28-imposed brake on RLR transcription

269 B sheet and indirectly shorten B strands by disengaging the backbones of the flanking residues from

270 c mutations activate FGFRs and other RTKs by disengaging the brake either directly or indirectly.

271 terminating TCR signaling and simultaneously disengaging the CTL from the target cell to allow serial

272 CD3(+) T cell compartment in the spleen and disengaging the hyperactivation state in the memory T su

273 enhancing the affinity for the substrate and disengaging the inhibitor by 20 to 286 and 5- to 3-folds

274 ha-DOG initiate downstream signaling without disengaging the N-terminal fragment from its C-terminal

275 es metastasis and prolongs mouse survival by disengaging the Shh-IL6-RANKL signaling network in strom

276 or 2 on breast tumour cells can be halted by disengaging the T cells from the tumour cells via the in

277 Of the 9,005 who disengaged, the 2 most common initial outcomes were retu

278 pamycin complex 1 (mTORC1) signaling pathway disengages, the mitochondria network fragments, cristae

279 tegies than younger adults, while failing to disengage their default-mode network during learning.

280 of circularly arranged F protein trimers may disengage them from pulling the membrane centrifugally,

281 However, FEN1 disengaged these nonproductively bound Dna2 molecules, p

282 ehaviors remain unclear, and whether opioids disengage those systems is unknown.

283 esult, the RVM neurons downstream of LHA are disengaged, thus suppressing nociception.

284 How CTLs terminate signaling and disengage to allow serial killing has remained a mystery

285 device 20 mm proximal to the ankle, manually disengaged to allow semi-constrained motion of the synde

286 ic TolB, which, as recent evidence suggests, disengages TolB from its interaction with other componen

287 peptides that are unable to conformationally disengage TPN from class I molecules are excluded from t

288 dic reaction times, and reduced latencies to disengage visual attention.

289 ly developing toddlers had more difficulties disengaging visual attention from faces than toddlers wi

290 in response to the ion motive force, clearly disengage when conditions change.

291 distinct kinds of memories: (1) one that was disengaged when the brain detected a change in the task

292 d by a unique Dbf4 inhibitory loop, which is disengaged when the kinase core assumes wobbling conform

293 DNA template for RNA priming and growth and disengages when needed to generate the elongation comple

294 ly in centrioles that were both modified and disengaged, whereas unmodified centrioles, engaged or no

295 -cadherin by means of their adaptors became "disengaged" while their protein levels were significantl

296 RTICLE: Brain regions dynamically engage and disengage with one another to execute everyday actions f

297 , pallidal, and striatal neurons engaged and disengaged with cortical beta bursts to different extent

298 aged most frequently overall (P < .0005) but disengaged with forces not significantly different (P >

299 T in human cells with long telomeres that is disengaged with increased cell divisions as telomeres pr

300 By ordinally engaging and disengaging with DNA, the FtsK motor unidirectionally tr