ライフサイエンスコーパス: disseminated

1 y increase as more complex genomic tests are disseminated.

2 ntial, it must be simplified and more widely disseminated.

3 "rheumatogenic" than others has been widely disseminated.

4 ection were identified; 8 were classified as disseminated (89%).

5 This knowledge is disseminated across all public data; it is a living data

6 ytes (VSTs) to treat maternally-transmitted, disseminated adenovirus infection in a premature infant.

7 yet we know little of how tumor material is disseminated among the large variety of antigen-presenti

8 e cases of histoplasmosis were identified: 2 disseminated and 7 pulmonary.

9 ness of this fungus' potential link to cause disseminated and invasive fungal infections.

10 vaccine in common use, is effective against disseminated and meningeal TB in young children but is n

11 KS is a highly disseminated and vascularized tumor.

12 ltistage infection, consisting of localized, disseminated, and persistent disease stages, impacting s

13 ermissiveness of Aedes aegypti mosquitoes to disseminated arboviral infections.

14 ncers metastasize to the brain; those widely disseminated are fatal typically in 3-4 months, even wit

15 evaluate its potential in patients with more disseminated bone involvement or visceral metastasis.

16 trates the utility of MSCs as OV carriers to disseminated brain lesions, and provides a clinically ap

17 Multiple, disseminated brain lesions, that are characterised by re

18 We diagnosed the lesions as disseminated brain metastases due to lung cancer.

19 Disseminated breast cancer cells employ adaptive molecul

20 aggregations, however, cuticular lipids are disseminated by contact among group members, including n

21 apenemase genes, and that these genes may be disseminated by non-Enterobacteriaceae that are not dete

22 Based on information disseminated by responding health departments and Center

23 While vascular niches host disseminated cancer cells and promote their stemness, en

24 ile tumor-initiating cells are Lgr5(+), most disseminated cancer cells are Lgr5(-) and seed liver met

25 dings reveal an important mechanism by which disseminated cancer cells can coopt the inflammatory ECM

26 How disseminated cancer cells cope with hostile microenviron

27 We hypothesize large, diverse, and disseminated cancer populations can be eradicated using

28 Chronic disseminated candidiasis (CDC) is a rare disease that mo

29 essential for virulence in a mouse model for disseminated candidiasis and that the cellular functions

30 In in vivo experimental models of disseminated candidiasis, C. auris was less virulent tha

31 of host-directed compounds for treatment of disseminated candidiasis.

32 humans, responsible for approximately 20% of disseminated candidiasis.

33 Using finely disseminated carbonates precipitated in paleosols from t

34 Of the disseminated cases, 8 patients required hospitalization,

35 stemic antifungal medication, including both disseminated cases.

36 gy, leading to the proliferation of globally disseminated cattle specialists of major public health i

37 cal inference framework indicates that early disseminated cells commonly (81%, 17 out of 21 evaluable

38 therapies which prevent the colonisation of disseminated cells into metastatic lesions are required.

39 )/NDL mice revealed a reduced association of disseminated cells with platelets and white blood cells.

40 septic state with leaky capillary syndrome, disseminated coagulopathy, and high mortality with limit

41 history of non-central nervous system (CNS) disseminated coccidioidomycosis (DCM) has not been previ

42 chronic fibrocavitary pulmonary disease, and disseminated coccidioidomycosis (DCM).

43 Groups were identified as non-disseminated coccidioidomycosis (non-DCM, 462 patients),

44 We describe a case of life-threatening disseminated coccidioidomycosis in a previously healthy

45 Like most patients with disseminated coccidioidomycosis, this child had no genom

46 unction on the cell surface can also lead to disseminated complement-dependent macrovascular thrombos

47 The widely disseminated convergence in physical appearance hypothes

48 s with cSAH versus those without, especially disseminated cortical superficial siderosis (49% vs 19%;

49 signaling is critical for the progression of disseminated CRCs.

50 Disseminated cryptococcosis occurred in 7 (22%) low-tite

51 databases, searched the grey literature, and disseminated data requests to international experts and

52 internet, and grey literature databases, and disseminated data requests via social media and targeted

53 CRCs from adenocarcinoma (6 weeks), to local disseminated disease (11-12 weeks), and spontaneous meta

54 ent vaccine protected offspring against nHSV-disseminated disease and mortality.

55 Most patients present with disseminated disease and the majority are offered pallia

56 Severe and disseminated disease is especially common in HIV-infecte

57 In contrast, in a disseminated disease model designed to reflect low-burde

58 orn in countries with high TB prevalence and disseminated disease occurred in 22.6%.

59 orse overall survival among patients who had disseminated disease receiving sodium thiosulfate than a

60 nct anatomical sites, as well as controlling disseminated disease that is known or assumed to be pres

61 m chimaera prosthetic valve endocarditis and disseminated disease were notified in Europe and the USA

62 r are diagnosed with locally advanced and/or disseminated disease, and treatment options include surg

63 Infection with Candida albicans, disseminated disease, pneumonia, and cardiovascular dise

64 In patients with disseminated disease, serum CrAg sensitivity by LA was 7

65 earchers are focusing on clinically to treat disseminated disease.

66 tion provides a therapeutic vulnerability in disseminated disease.

67 e, ranging from local pulmonary infection to disseminated disease.

68 ompromised immune systems can develop severe disseminated disease.

69 atients received systemic therapy for widely disseminated disease.

70 e first line of therapeutic intervention for disseminated disease.

71 ns range from self-limited disease to severe disseminated disease.

72 as a promising approach to the treatment of disseminated disease.

73 organ systems and can cause life-threatening disseminated disease.

74 was fever, without any specific pattern, and disseminated disease.

75 matic to life-threatening acute pulmonary or disseminated disease.

76 7% compared to 100% for LFA in patients with disseminated disease.

77 DLBCL, MCL, and disseminated EMZL and FL were primarily treated with che

78 rders like multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM) have been difficul

79 romes and with encephalitis other than acute disseminated encephalomyelitis (ADEM) recruited from 40

80 MOG-Abs were reported in children with acute disseminated encephalomyelitis (ADEM).

81 e central nervous system diseases like acute disseminated encephalomyelitis (ADEM).

82 tis (n = 2, para- or post-infectious), acute disseminated encephalomyelitis (n = 9), with haemorrhage

83 their presenting phenotype: those with acute disseminated encephalomyelitis demonstrated abnormal tra

84 participants, as did patients with non-acute disseminated encephalomyelitis presentations associated

85 8%) and adults (55.9%, p = 0.013), and acute disseminated encephalomyelitis syndrome was more frequen

86 omyelitis optica spectrum disorder and acute disseminated encephalomyelitis) and from non-demyelinati

87 had immune-mediated encephalitis, 18% acute disseminated encephalomyelitis, and 6% anti-N-methyl-d-a

88 ptica spectrum disorders and relapsing acute disseminated encephalomyelitis, and characterizing cohor

89 include encephalopathy, encephalitis, acute disseminated encephalomyelitis, meningitis, ischemic and

90 The high incidence of acute disseminated encephalomyelitis, particularly with haemor

91 If disseminated, "Engage" will increase the number of thera

92 Treatment of mice with disseminated ER+ human breast cancer showed that D9 plus

93 The Pain Resource Nurse program is a widely disseminated, evidence-based, nursing staff development

94 oke quality initiative in January 2010 which disseminated feasible strategies to shorten door-to-need

95 s, knowledge and tools must be developed and disseminated for individuals who provide pancreatic canc

96 obacterium bovis BCG) protects children from disseminated forms of TB but does not effectively protec

97 n, then to tuberculosis disease and possibly disseminated forms of tuberculosis, with accompanying hi

98 rench military consisted mainly of adenitis; disseminated forms were possible with immunodeficiency.

99 confer antibiotic resistance can rapidly be disseminated from one microorganism to another by mobile

100 sequences and plasmids will be archived and disseminated from open source suppliers.

101 lung, pancreas, kidneys, and bone, that have disseminated from the primary site, are reported.

102 razil by February 2014 and is likely to have disseminated from there, nationally and internationally,

103 enues, we need a deeper understanding of the disseminated functional-anatomic network and its tempora

104 start of Imatinib therapy in inoperable and disseminated GIST patients, specific CT images, not seen

105 belonging to sequence type 131 (ST131) have disseminated globally during the last 30 years, leading

106 ycoprotein gene, emerged in 1999 and quickly disseminated globally replacing other RSV group B genoty

107 te as the sixteenth century and subsequently disseminated globally.

108 nfrequently, Neisseria gonorrhoeae can cause disseminated gonococcal infection (DGI).

109 Metastasis-the disseminated growth of tumours in distant organs-underli

110 al superficial siderosis (focal, </=3 sulci; disseminated, >/=4 sulci), and key small vessel disease

111 itis who subsequently developed pulmonary or disseminated histoplasmosis at the Mayo Clinic in Roches

112 Both patients with disseminated histoplasmosis were taking tumor necrosis f

113 review the published cases of biopsy-proven disseminated histoplasmosis with cholestatic jaundice to

114 osure events and may indicate higher risk of disseminated histoplasmosis, especially in HIV infected

115 Though liver involvement is common in disseminated histoplasmosis, primary gastrointestinal hi

116 omodulatory therapy may develop pulmonary or disseminated histoplasmosis.

117 mab was discontinued in 1 patient because of disseminated histoplasmosis.

118 ization of the spleen demonstrated extensive disseminated HIV infection, likely initiated from in viv

119 et genes and thereby thwarted progression of disseminated HL-60 leukemia.

120 The deliverables from these groups are being disseminated in 4 stand-alone articles, and their public

121 ario wherein the polydispersed bioaerosol is disseminated in bulk over any geographical setting.

122 Guidelines were disseminated in conjunction with postsurgical pain manag

123 for reducing conduct problems and is widely disseminated in Europe.

124 disease lies in the CNS destruction process disseminated in time and space.

125 Autopsy showed disseminated infection and midzonal hepatitis with apopt

126 our data indicate that bbk13 contributes to disseminated infection by promoting spirochete prolifera

127 Disseminated infection due to M. bovis is otherwise unco

128 val in mammalian hosts, particularly for the disseminated infection in distant organs.

129 imaging further supported a more severe and disseminated infection in WT neonates.

130 -grade candidemia to determine the effect of disseminated infection on cerebral function and relevant

131 Most of the reported cases present with a disseminated infection that is striking in both the late

132 HRTV can cause rapidly fatal, widely disseminated infection with multisystem organ failure in

133 opathologic ocular findings in patients with disseminated infection with Mycobacterium chimaera, a sl

134 bloodstream of vulnerable patients, causing disseminated infection.

135 uch as Candida albicans, capable of invasive disseminated infection.

136 mucormycosis, causing over 90% mortality in disseminated infection.

137 rovides nonredundant defense against lethal, disseminated infection.

138 ity of congenitally-acquired ZIKV to produce disseminated infections and the viral tropism towards ep

139 These disseminated infections often arise without a defined po

140 dii is an intracellular parasite that causes disseminated infections that can produce neurological da

141 and tissue vascular barriers and establishes disseminated infections will contribute to the developme

142 Disseminated infections with the fungal species Cryptoco

143 rulence of fungal pathogens in pulmonary and disseminated infections, and we show here an additional

144 s and are responsible for potentially lethal disseminated infections.

145 he iCBT should be addressed before it can be disseminated into routine care.

146 se of intrapartum convulsion and one case of disseminated intravascular coagulation (both in the Fole

147 ed coagulation system with increased risk of disseminated intravascular coagulation (DIC) and venous

148 ed coagulation system with increased risk of disseminated intravascular coagulation (DIC) and venous

149 activated platelets in inflammation-induced disseminated intravascular coagulation (DIC) in micro-ca

150 Reports of widespread thromboses and disseminated intravascular coagulation (DIC) in patients

151 Disseminated intravascular coagulation (DIC) is a condit

152 scribe high venous thromboembolism (VTE) and disseminated intravascular coagulation (DIC) rates, but

153 Disseminated intravascular coagulation (DIC)-positive ki

154 coagulation system leads to life-threatening disseminated intravascular coagulation (DIC).

155 M173 pathway correlates with the severity of disseminated intravascular coagulation and mortality in

156 of NET formation could independently predict disseminated intravascular coagulation and mortality, wh

157 Sequential Organ Failure Assessment scores, disseminated intravascular coagulation, and 28-day morta

158 VTE patients, for diagnosing and monitoring disseminated intravascular coagulation, and as an aid in

159 cluding acute respiratory distress syndrome, disseminated intravascular coagulation, and multiorgan f

160 ailure, acute respiratory distress syndrome, disseminated intravascular coagulation, and, rarely, dea

161 CRS may develop capillary leak syndrome and disseminated intravascular coagulation, with a cytokine

162 eiving anticoagulants fulfilled criteria for disseminated intravascular coagulation.

163 Death was attributed to sepsis and disseminated intravascular coagulation.

164 been used for treatment of sepsis-associated disseminated intravascular coagulation.

165 atients develop thromboembolism, and rarely, disseminated intravascular coagulopathy (DIC), with pati

166 mmatory changes as observed in patients with disseminated intravascular coagulopathy (DIC).

167 ent with hemostatic abnormalities that mimic disseminated intravascular coagulopathy associated with

168 Based on these findings, disseminated ischaemic lesions were diagnosed.

169 ine and COVID-19 but also how we learned it, disseminated it, and put it into practice.

170 Initial brain MRI revealed multiple, disseminated lesions that were hyperintense on T2-weight

171 In adoptive therapy of disseminated leukemia, CD200R-CD28-transduced leukemia-s

172 manifestation from mild pulmonary symptom to disseminated, life-threatening disease.

173 estigated the pathology associated with late disseminated Lyme disease (12 to 13 months after tick in

174 tients with OA-MCL frequently presented with disseminated lymphoma (n = 34 of 55; 62%), and were like

175 CG) angiography findings, of patients with a disseminated M. chimaera infection.

176 ees C), whereas ~20%, mainly vein-hosted and disseminated magnetite, match the low-temperature refere

177 procedures (45.3% vs. 32.4%, P = 0.02), had disseminated malignancies (9.4% vs. 2.8%, P = 0.03), and

178 he diagnosis of Lyme carditis (LC), an early disseminated manifestation of Lyme disease, has importan

179 ression in a cell line established from bone-disseminated MCF7 cells (MCF7b), which were more migrato

180 uppress the growth of intradermal tumors and disseminated melanoma lacking the Trm cell-targeted epit

181 bility, thus oAd cannot be utilized to treat disseminated metastases.

182 alignancy and is characterized by peritoneal disseminated metastasis.

183 tic disease were compared with patients with disseminated metastatic disease.

184 1b due to extrathoracic lymph nodes only) or disseminated metastatic disease.

185 rombocytopenia, and organ ischemia linked to disseminated microvascular platelet rich-thrombi.

186 imens and had a robust antitumor effect in a disseminated MM mouse model.

187 bined immunodeficient mice bearing solid and disseminated MM tumors.

188 but not TRBC2(+), T cells in vitro and in a disseminated mouse model of leukemia.

189 958, a representative strain of the globally disseminated multidrug-resistant UPEC ST131 clone, to zi

190 cent work focusing on the virulent, globally disseminated, multidrug-resistant lineage ST131.

191 d DOTA-daratumumab in a preclinical model of disseminated multiple myeloma.

192 Pleural disseminated, mutant KRAS bearing tumour cells upregulat

193 fter observing the improvement of refractory disseminated mycobacterial infection in a CD40L-deficien

194 year-old patient with cystic fibrosis with a disseminated Mycobacterium abscessus infection was treat

195 med whole-exome sequencing of a patient with disseminated Mycobacterium abscessus, Streptococcus viri

196 We used a model of disseminated Mycobacterium avium infection in mice to in

197 e report the cases of 3 patients with fatal, disseminated Mycobacterium chimaera infections following

198 Invasive and disseminated Mycoplasma hominis infections are well reco

199 istopathological evidence suggest that fatal disseminated N. animaloris infections had occurred due t

200 We investigated a disseminated neoplasia affecting geographically distant

201 mmunodeficiency virus-infected patients with disseminated nontuberculous mycobacterial (NTM) disease.

202 een underdiagnosed, our results suggest that disseminated NTM disease may cause false-positive LF-LAM

203 There are limited data on the development of disseminated or pulmonary histoplasmosis among patients

204 Patients had to develop either disseminated or pulmonary histoplasmosis while receiving

205 ed, conducted, analysed, regulated, managed, disseminated, or reported.

206 o >90 days in a cell-line xenograft model of disseminated ovarian cancer.

207 with orthotopic PaCa and cured peritoneally disseminated PaCa with no toxic side effects, in contras

208 CASE REPORT: We describe a patient with a disseminated pancreatic NEN that presented with an isola

209 Nontyphoidal Salmonella species are globally disseminated pathogens and are the predominant cause of

210 Unless guidelines are established and disseminated, penile transplants should not be undertake

211 tive Lyme borreliosis in patients presenting disseminated persistent infection.

212 infects vascular endothelial cells producing disseminated plasma leakage, manifesting as nonspecific

213 emical analyses demonstrated the presence of disseminated platelet-rich thrombi in terminal arteriole

214 s to achieve gene transfer throughout highly disseminated primary brain tumors.

215 ed with cerebral venous sinus thrombosis and disseminated primary JCPyV infection originating from th

216 enges the prevailing view of metastasis as a disseminated process and proposes the existence of a spe

217 perspective that metastasis is an invariably disseminated process, and proposes a biological spectrum

218 In this inhalational model, toxins have disseminated rapidly in the blood, playing a significant

219 Although some widely disseminated recommendations are supported by the resear

220 ctice, while also allowing for validation of disseminated research.

221 UMO motif ((702)IKTE(705)) in a patient with disseminated Rhodococcus species infection, Norwegian sc

222 drial mass increase in a murine NSG model of disseminated SEM cell-derived ALL, wherein CD19+ cells c

223 rgement of the lesions; there were multiple, disseminated, sharply outlined, contrast-enhancing, oval

224 y and often spread to various target organs: disseminated skin sites, the central nervous system, the

225 atures, risk factors, and treatment of these disseminated sporotrichosis cases, and discuss the need

226 gangrenosum, and subsequently progressed to disseminated sporotrichosis in the setting of iatrogenic

227 terium-fungus infectious synergy, leading to disseminated staphylococcal disease.

228 or to a single dose for the treatment of non-disseminated strongyloidiasis.

229 refore be preferred for the treatment of non-disseminated strongyloidiasis.

230 show that each skin lesion of disseminated superficial actinic porokeratosis originate

231 phil recruitment and fungal virulence during disseminated systemic C albicans infections.

232 It normally causes localized or disseminated systemic diseases, particularly skin infect

233 The bacteria disseminated systemically and spread to several organs a

234 Rather than being a non-specific diagnosis, disseminated TB is a distinct, life-threatening conditio

235 etter characterise the clinical phenotype of disseminated TB.

236 transplantation, manifesting as pulmonary or disseminated TB.

237 The results of this study will be disseminated through a series of published articles.

238 on; however, treatment increasingly is being disseminated through community- and commercial-based pro

239 used to develop an on-line survey which was disseminated through health care professional networks w

240 loids applied into the trachea may either be disseminated through the circulation and cross the blood

241 rom a single transformed melanocyte and then disseminated throughout the integument.

242 a large repertoire of memory IgM(+) B cells disseminated throughout the intestine but rare in system

243 ls of certain genes indicate they are widely disseminated throughout the microbial population, potent

244 Rheumatic fever-associated emm types were disseminated throughout the phylogeny, suggesting they b

245 loads, and how PRIDE data are starting to be disseminated to added-value resources including Ensembl,

246 An online questionnaire was disseminated to Australian practicing members of the Aus

247 osis is a late posttransplant infection that disseminated to biliar duct or lung in 9% of patients.

248 s, and summary statistics must be publically disseminated to ensure that health disparities are not i

249 ess consequences in vitro, all 38T/M viruses disseminated to naive ferrets by contact and airborne tr

250 udies indicated that spores without anthrose disseminated to organs more extensively than a complemen

251 The findings will also be disseminated to the local government, stakeholders withi

252 prolactin receptor as cancer cells that have disseminated to the lungs expand into micrometastases.

253 The 2002 and 2007 guidelines were widely disseminated, translated into Spanish and Portuguese, an

254 Disseminated TRM lodgment was seen with the skin, but re

255 obiologic determinants of mortality included disseminated tuberculosis (positive urine lipoarabinoman

256 ith pulmonary tuberculosis was found to have disseminated tuberculosis and a clinically unsuspected p

257 The final imaging diagnosis was disseminated tuberculosis complicated by splenic vein th

258 We also show that disseminated tuberculosis is often difficult to diagnose

259 Although disseminated tuberculosis is well documented in HIV-posi

260 Disseminated tuberculosis, sepsis syndrome, and rifampic

261 mediators and death as well as biomarkers of disseminated tuberculosis.

262 < 0.001) and with detection of biomarkers of disseminated tuberculosis.

263 ive refugees, who presented with extensively disseminated tuberculosis.

264 e widespread gene transfer throughout highly disseminated tumor areas within the brain.

265 We examine the impact of the matrix on disseminated tumor cell extravasation and on tumor dorma

266 However, the fate of these early disseminated tumor cells (DTC) remains elusive.

267 n, many patients with cancer harbor a myriad disseminated tumor cells (DTC) throughout the body, most

268 , physiological, and molecular properties of disseminated tumor cells (DTC).

269 s to evaluate the prognostic significance of disseminated tumor cells (DTCs) and circulating tumor ce

270 teps of metastasis, including the seeding of disseminated tumor cells (DTCs) to bone, the survival of

271 Disseminated tumor cells (DTCs) undergo a dormant state

272 mitters, and their potential for sterilizing disseminated tumor cells (DTCs), it is critical to deter

273 or cancer cells, as only a small fraction of disseminated tumor cells can overcome the numerous hurdl

274 s, we show metabolic phenotyping on the rare disseminated tumor cells in pleural effusions across a p

275 monocytes and tumoricidal neutrophils target disseminated tumor cells in the lungs, preventing metast

276 a bulky glycocalyx promotes the expansion of disseminated tumor cells in vivo by fostering integrin a

277 eous metastasis and enables the outgrowth of disseminated tumor cells into overt macro-metastases.

278 tinib as a means to stabilize the latency of disseminated tumor cells.

279 ronment is essential to facilitate growth of disseminated tumor cells.

280 Delayed recurrences arise from disseminated tumors cells (DTCs) in sites such as bone m

281 Sequencing of primary and disseminated tumors confirmed the presence of oncogenic

282 Disseminated tumors to the bone and lung are easily dete

283 as an effective therapeutic strategy against disseminated tumors.

284 tumour cells (CTCs) and bone marrow-derived disseminated tumour cells (BM-DTCs) can offer clinically

285 The presence of disseminated tumour cells (DTCs) in bone marrow is predi

286 How disseminated tumour cells engage specific stromal compon

287 al transition and cancer stem cell traits in disseminated tumour cells is provided by bone vascular n

288 Most disseminated tumour cells that arrive in distant tissues

289 Within the bone, these disseminated tumour cells, as well as those arising in t

290 animals enhance metastatic growth of already disseminated tumour cells.

291 It is also thought that these bacteria are disseminated via the bloodstream to other organs.

292 for controlling adenoviremia and preventing disseminated viral disease in hematopoietic cell transpl

293 vaccination against rapidly evolving, widely disseminated viruses like human norovirus.

294 During NF1 and NF2 mixed infection, only NF1 disseminated, while NF2 was rapidly killed by a contact-

295 asticity towards pro-inflammatory cytokines, disseminated widely into the periphery, and engaged aero

296 While utilization of CTO PCI has disseminated widely, the learning curve for new operator

297 evolution and improvement of wheat as it was disseminated worldwide remains unknown.

298 survival when testing I-BET151 efficacy in a disseminated xenograft MLL mouse model, whereas the orig

299 (IRR, 3.6 [95% CI, 3.5-3.7]) and highest for disseminated zoster (IRR, 32.8 [95% CI, 27.8-38.6]).

300 lts (IRR=3.6, 95%CI 3.5-3.7) and highest for disseminated zoster (IRR=32.8, 95%CI 27.8-38.6).