ライフサイエンスコーパス: distend

1 c or nearly so, and many of the vessels were distended.

2 ntrol glands the alveoli remained intact and distended.

3 activated only when the wall of the bowel is distended.

4 of zymogen granules, and the ER is severely distended.

5 and to re-emerge in the urine as the bladder distended.

6 The crop was hyper-distended 6 h after a satiating meal of rehydrated seawe

7 His physician noted a mildly distended abdomen that was diffusely tender on palpation

8 Physical examination revealed a distended abdomen with tenderness at palpation within th

9 ls; have a paucity of secreted IgH; and have distended, abnormal-appearing endoplasmic reticulum.

10 environment to a pathogen-rich, rhythmically distended air-liquid interface.

11 forms, the carboxy-terminal helices of HslU distend and bind between subunits of HslV, and the apica

12 od vessel, and alveolus, where they serve to distend and stabilize structures that would otherwise co

13 Mural attenuation was measured in the distended and collapsed jejunal and ileal loops and in t

14 Instead, capillaries were distended and exhibited a ballooned appearance, a phenot

15 cular beds are specified, but the aortae are distended and lack contact with the surrounding mesenchy

16 abnormal vascular morphogenesis resulting in distended and leaky capillary vessels, as well as aberra

17 hysical examination revealed her abdomen was distended and nontender.

18 s, and capillaries within the tumor appeared distended and sinusoidal.

19 increase the risk of bowel injury given the distended and/or potentially compromised small bowel.

20 ocytes may be caused by increased mechanical distending and shear forces and/or impaired adhesion to

21 The aortic root was still grossly distended, and the conductive myocytes retained storage,

22 aching confirms that chromatin indeed flows, distends, and reorganizes while the lamina stretches.

23 ography of the abdomen and pelvis revealed a distended appendix (> 1.3 cm) and a fistula between the

24 Abeta accumulated in perinuclear regions and distended axons within the forebrains of these mice.

25 urgically prepare a mouse for CRD, construct distending balloons, distend the colon, and accumulate a

26 virions to exit the midgut by traversing the distended basal lamina to infect secondary tissues of th

27 rences in centromere morphology, including a distended bead-like structure in interphase root tip cel

28 ew meal despite the fact that their crop was distended beyond the level at which they had previously

29 Hpse2 knockout mutants display a distended bladder (megacystis) phenotype and abnormal vo

30 utant mice die perinatally showing a greatly distended bladder, underdeveloped diaphragm and a reduct

31 ATP concentrations in the perfusate from non-distended bladders and inhibited increases in ATP concen

32 ls with impaired light response, and grossly distended bladders.

33 y retinal changes (P = .29), the presence of distended bordering vessels (P = 1), visualization of th

34 Distended bordering vessels were identified in 22 nevi (

35 Distended bordering vessels were recognized in over two

36 l loops demonstrate greater attenuation than distended bowel loops.

37 ibited two patterns of involvement: either a distended bursa or multiple small abscesses.

38 e aortas were suspended in a saline bath and distended by means of a saline fluid column.

39 vessels in tumors are often highly abnormal, distended capillaries with leaky walls and sluggish flow

40 Pressures distending carotid and aortic baroreceptors were control

41 uit allowed independent control of pressures distending carotid, aortic and coronary baroreceptors.

42 euronal response to KCl, but not DMPP in the distended colon.

43 decreased for polyps less than 10 mm, poorly distended colonic segments, and other shape algorithms.

44 0 of 14) for polyps 10 mm or greater in well-distended colonic segments.

45 t visible of the three teniae coli on a well-distended colonic surface, was manually extracted from t

46 conditional mutants exhibit retarded growth, distended colons, and premature death, resembling human

47 es with abnormal retention of lipids causing distended cytoplasmic vacuoles compared to the HFE hens.

48 nnective tissue compartments accountable for distending digital pulp under normal circumstances and s

49 three morphological phenotypes are observed: distended ducts, supernumerary end buds, and ectopic aci

50 on even when the veins of the lower limb are distended due to the presence of a physiologic hydrostat

51 e first, a 24-year-old patient, they noticed distended duodenum filled with fluid and a dilated gallb

52 cellular phenotype characterized by grossly distended endoplasmic reticulum (ER) and retention of pr

53 tion of the beta subunit (LanB1), leading to distended endoplasmic reticulum (ER), ER stress, and gli

54 llection unrelated to leak (n = 9), markedly distended excluded stomach (n = 6), small-bowel obstruct

55 is, chemosis, exposure keratopathy, markedly distended eyelids and often, loss of vision.

56 aking them easier to engulf with the snail's distended false mouth, which functions as a net.

57 nd NO synthesis, intermittent compressive or distending forces applied to ex vivo nonbeating hearts w

58 e show neonatal lethality characterized by a distended gastrointestinal tract.

59 tubule and duct, (2) the fleer mutation with distended glomerular capillary loops and cystic tubules,

60 iRNA knockdown or in ARCL2 cells resulted in distended Golgi cisternae, accumulation of abnormal lyso

61 L1-L5 and S3 segments compared with the sham distended group or with animals that received no treatme

62 Discrete aggregates of distended hepatocytes with central nuclei and nonvacuola

63 s had significantly greater attenuation than distended ileal loops (113 HU vs 72 HU; P < .001).

64 ty bladders, whereas bladders were uniformly distended in mutant mice, a defect ameliorated by AAV9/H

65 The Fecobionics bag was distended in rectum until urge in 37 female patients (64

66 mitochondria with blebs of herniated matrix, distended inner membrane and partial loss of cristae str

67 % mortality, reduced growth, emaciated body, distended intestinal lumen, rectal swelling, and prolifi

68 leal (108 HU) loops was greater than that of distended jejunal and ileal loops (P < .001).

69 Distended jejunal loops had significantly greater attenu

70 The distended jejunum was accessed with a 21-gauge needle, i

71 Following fundoplication, the stomach distended like a balloon without leakage of air through

72 At 1 day post-partum, lactationally active, distended lobuloalveoli failed to form.

73 was performed with both nuclear "halos" with distended loops and the nuclear matrix after the majorit

74 High distending lung pressures increased oxygenation but decr

75 ection of host cells, leading to reversal of distended lysosomal pathology and regional clearance of

76 FEB/TFE3 are made active in macrophages with distended lysosomes.

77 myosin-II, and so multinucleated cells with distended membranes--typical of megakaryocytes (MKs)--se

78 siological buffer, and we describe a stable, distended network consistent with the spectrin cytoskele

79 particularly useful if the abdomen is tense, distended, obese, or very tender.

80 , in null transplants, ducts were frequently distended or irregularly shaped and showed a range of hi

81 ely on a scale of 1-4 (1, segment completely distended or no residual material; 4, segment collapsed

82 ries become altered, and they are frequently distended or swollen, presumably affecting synaptic tran

83 length, sex, tympanum diameter, presence of distended oviducts or eggs for females, and testes lengt

84 g in the myelin lamellae of the sheath and a distended periaxonal space between the axon and myelin s

85 of the H. pullorum strains induced cellular distending phenotype, actin cytoskeleton remodeling, and

86 In contrast, minimal systolic width of the distended pressure-loaded mitral valve was not significa

87 ce, and enhanced left ventricular transmural distending pressure (all P <0.01), with no increase in p

88 coronary baroreceptors after maintaining the distending pressure at 60 or 180 mmHg for 20 min.

89 After re-establishment of a normal distending pressure by stenting of severe coronary steno

90 An optimal continuous distending pressure close to the point of maximal curvat

91 Following lavage, the Xrs-continuous distending pressure curves presented a maximum on the de

92 iffness and vasodilatation, as a function of distending pressure derived by photo-plethysmographic vo

93 the relationship between Zrs and continuous distending pressure during an increasing/decreasing cont

94 ography-derived lung volume, high continuous distending pressure had adverse cardiopulmonary effects.

95 l; 3) to evaluate how the optimal continuous distending pressure identified by Zrs relates to the poi

96 We hypothesized that high continuous distending pressure impedes pulmonary blood flow as evid

97 cy ventilation was initiated at a continuous distending pressure of 10 cm H2O and incrementally incre

98 trial appendages (n=78) were cannulated at a distending pressure of 60 mm Hg and zero flow.

99 time of cardiac surgery and cannulated at a distending pressure of 60 mm Hg and zero flow.

100 lung mechanics and improving the continuous distending pressure optimization during high-frequency o

101 tion limb, identifying an optimal continuous distending pressure that was, on average, 1.1 +/- 1.7 cm

102 minates throughout gestation and generates a distending pressure to stretch the lung and stimulate gr

103 measuring Zrs during a decreasing continuous distending pressure trial.

104 were determined at the end of the continuous distending pressure trial.

105 e during an increasing/decreasing continuous distending pressure trial; 3) to evaluate how the optima

106 Zrs was measured while continuous distending pressure was increased and decreased between

107 ary arterioles (diameter, 90.0+/-3.4 microm; distending pressure, 20 mm Hg) preconstricted by 30% to

108 Provided transpulmonary pressure is the lung-distending pressure, and that chest wall elastance may v

109 ation relies on the generation of a constant distending pressure, small tidal volumes and rapid respi

110 measured vasoconstriction in vessels with no distending pressure.

111 by providing more direct assessment of lung distending pressure.

112 coronary arteries markedly varies with their distending pressure.

113 nts with high Ers are at risk of excess lung-distending pressures and may derive greater clinical ben

114 rtic compliance over a wide range of passive distending pressures, and to study pharmacologically ind

115 esected human appendix stimulated by noxious distending pressures.

116 se responses are observed at abnormally high distending pressures.

117 l collagen that is more pronounced at higher distending pressures.

118 are grossly misshapen, with constricted and distended regions all along their lengths.

119 ally and reversibly silencing neurons in the distended regions.

120 bservations of peritumoral rims demonstrated distended sinusoidal spaces giving rise to new tumor-pen

121 Hypoechoic rims correlated with distended sinusoidal spaces in vivo.

122 ith laparoscopic approaches in patients with distended small bowel.

123 ic vasoconstrictor responsiveness relates to distended smooth muscles or to endotoxemia and/or hypoxi

124 Symptoms increased with distending stimulus intensity (maximum pain, 2.1 +/- 0.4

125 reased activity following termination of the distending stimulus whereas Type II neurons typically ha

126 agments thereof shows that the protein has a distended structure in solution, in contrast to helicase

127 lungs are smaller than normal, with grossly distended terminal buds and, at birth, contain large air

128 phy (HRCT) to examine the ability of a DI to distend the airways of subjects with asthma (n = 10) com

129 ouse for CRD, construct distending balloons, distend the colon, and accumulate and analyze data from

130 se smallest scales, physical forces serve to distend the cytoskeleton, drive cytoskeletal remodeling,

131 preparation with oral or rectal contrast to distend the lumen and improve the definition of the inte

132 iopsy channel was connected to a barostat to distend the stomach with air at 15 mm Hg for 30 minutes.

133 Furthermore, MEQ is able to distend the transforming capacity of MEQ-transformed Rat

134 duction of smooth muscle tone with MCh, a DI distended the airways of healthy and asthmatic subjects

135 ely filled the gland parenchyma and slightly distended the capsule.

136 ction to the perfusion circuit and pressures distending the aortic arch, carotid sinus and coronary a

137 blind-ending vessels from the ventral aorta, distending the arteries and precipitating fusion with an

138 le, when developed intraventricular pressure distends the leaflets, causing them to stretch and ballo

139 The Fluorinert enema distends the mouse colon, creating an artifact-free blac

140 fill the inner magnetosphere, their pressure distends the nightside magnetic field.

141 to the lumen of collapsed vessels (where it distends the vessel) and the space between two vessels (

142 When the bladder is distended, the urothelium functions as a sensor to initi

143 m sm-STIM1-KO mice developed abnormally with distended, thinned morphology.

144 roidal ER storage disease characterized by a distended thyrocyte ER containing misfolded Tg, along wi

145 ce suggest that microvessel walls have to be distended to a greater extent in cold tissue before P(B)

146 (100-200 ng), whereas the left ventricle was distended to activate cardiac mechanoreceptors.

147 alloon advanced through the mitral valve and distended to an end-diastolic pressure of 10 mm Hg.

148 The bacterial genotoxins cytolethal distending toxin (CDT) and colibactin cause severe DNA d

149 Haemophilus ducreyi makes cytolethal distending toxin (CDT) and hemolysin.

150 etemcomitans strains that express cytolethal distending toxin (Cdt) are associated with localized agg

151 eptible mouse strains, produces a cytolethal distending toxin (CDT) consisting of CdtA, CdtB, and Cdt

152 paticus expresses a member of the cytolethal distending toxin (CDT) family of bacterial cytotoxins.

153 hat represent a new member of the cytolethal distending toxin (CDT) family of bacterial toxins.

154 Cytolethal distending toxin (CDT) from the diarrheagenic bacterium

155 ents, we recently showed that the cytolethal distending toxin (Cdt) from the periodontal pathogen Agg

156 tion was reduced by flagellum and cytolethal distending toxin (CDT) gene mutants, treatment of the su

157 the role of the virulence factor cytolethal distending toxin (CDT) in the pathogenesis of this organ

158 Cytolethal distending toxin (CDT) induces cell cycle arrest and apo

159 The tripartite cytolethal distending toxin (CDT) induces cell cycle arrest and apo

160 Cytolethal distending toxin (CDT) is a multisubunit protein found i

161 Cytolethal distending toxin (CDT) is a newly described toxin produc

162 inobacillus actinomycetemcomitans cytolethal distending toxin (Cdt) is a potent immunotoxin that indu

163 egatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon the integrity o

164 egatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon the integrity o

165 The cytolethal distending toxin (Cdt) is produced from a number of bact

166 Because cytolethal distending toxin (CDT) may be a virulence factor, IL-10(

167 The cytolethal distending toxin (Cdt) of Actinobacillus actinomycetemco

168 The cytolethal distending toxin (CDT) of Actinobacillus actinomycetemco

169 The cytolethal distending toxin (CDT) of Campylobacter jejuni was detec

170 The cytolethal distending toxin (CDT) of Haemophilus ducreyi is compris

171 li cdtABC genes that comprise the cytolethal distending toxin (CDT) of this enteric pathogen.

172 Campylobacter jejuni-derived cytolethal distending toxin (CDT) promotes CRC metastasis through J

173 inobacillus actinomycetemcomitans cytolethal distending toxin (Cdt) results in dose-dependent G2 arre

174 B polypeptide of Escherichia coli cytolethal distending toxin (CDT) shares significant pattern-specif

175 Campylobacter jejuni encodes a cytolethal distending toxin (CDT) that causes cells to arrest in th

176 actinomycetemcomitans produces a cytolethal distending toxin (Cdt) that inhibits the proliferation o

177 hilus ducreyi expresses a soluble cytolethal distending toxin (CDT) that is encoded by the cdtABC gen

178 hilus ducreyi expresses a soluble cytolethal distending toxin (CDT) that kills HeLa, HEp-2, and other

179 A genetic locus for a cytolethal distending toxin (CDT) was identified in a polymorphic r

180 erichia coli strains that produce cytolethal distending toxin (CDT) were analyzed for their virulence

181 Moreover, the effects of the cytolethal distending toxin (CDT) were evaluated first by using a w

182 ne-associated protein subunits of cytolethal distending toxin (CDT) were unable to induce IL-8.

183 cytolethal distending toxin (Cdt), 4',6-diamidino-2-phenylindole (D

184 Many H. ducreyi strains express cytolethal distending toxin (CDT), and recombinant CDT causes apopt

185 The bacterial genotoxin, cytolethal distending toxin (CDT), causes DNA damage in host cells,

186 Abbreviations: cytolethal distending toxin (Cdt), connective tissue (CT), 4',6-dia

187 The cytolethal distending toxin (Cdt), expressed by the periodontal pat

188 A genetically modified cytolethal distending toxin (Cdt), from the periodontal pathogen Ag

189 ential virulence factors, such as cytolethal distending toxin (CDT), in vivo are poorly understood.

190 regions in the leukotoxin (lkt), cytolethal distending toxin (cdt), major fimbrial subunit (flp-1),

191 The cytolethal distending toxin (Cdt), produced by some clinically impo

192 ia have evolved a toxin, known as cytolethal distending toxin (CDT), that has the ability to control

193 code a multisubunit toxin, termed cytolethal distending toxin (CDT), that induces cell cycle arrest,

194 r jejuni produces a toxin, called cytolethal distending toxin (CDT), which causes direct DNA damage l

195 ny bacterial pathogens encode the cytolethal distending toxin (CDT), which causes host cells to arres

196 s were examined for production of cytolethal distending toxin (Cdt).

197 ossess virulence factors, such as cytolethal distending toxin (CDT).

198 -labile toxins, a hemolysin and a cytolethal distending toxin (CDT).

199 er jejuni produces a toxin called cytolethal distending toxin (CDT).

200 genome does not harbor genes for cytolethal distending toxin (cdt).

201 xic necrotizing factor (cnf), and cytolethal distending toxin (cdt).

202 l and pathogenesis, including the cytolethal distending toxin (CDT).

203 ; (b) the newly discovered toxin, cytolethal distending toxin (CDT); and (c) a secreted chaperonin 60

204 suppressive factor encoded by the cytolethal distending toxin (cdt)B gene, which is homologous to a f

205 suppressive factor encoded by the cytolethal distending toxin (cdt)B gene.

206 act homologs of the gene encoding cytolethal distending toxin (cdtB), which interrupts the eukaryotic

207 notably diarrhea-associated cdtB (cytolethal distending toxin [46%]) and urinary tract infection-asso

208 ed rat model of IBS-D (induced by cytolethal distending toxin [CdtB] inoculation).

209 We concluded that cytolethal distending toxin activity is a characteristic of C. jeju

210 Cytolethal distending toxin activity is a potential virulence deter

211 presence of the cdtB gene and for cytolethal distending toxin activity.

212 shed, but the association between cytolethal distending toxin and disease is incompletely understood.

213 the evolution of two toxin genes-cytolethal distending toxin B (cdtB) and apoptosis inducing protein

214 rcially available version of anti-cytolethal distending toxin B and anti-vinculin antibodies, and tes

215 ys residue, a CdtB homologue from cytolethal distending toxin can form a functional complex with ArtA

216 ylobacter coli, the production of cytolethal distending toxin correlated positively (P < 0.0001) only

217 Intoxication by cytolethal distending toxin depends on assembly of CdtB, the active

218 tion of the H. hepaticus-specific cytolethal distending toxin gene and showed similar animal coloniza

219 Sequence analysis of the cytolethal distending toxin gene cluster (cdt) also disclosed three

220 ted the role of LuxS in motility, cytolethal distending toxin production, agglutination, and intestin

221 cretion system needle protein, or cytolethal distending toxin revealed a direct correlation between t

222 encoding toxins of animal cells, cytolethal distending toxin subunit B (cdtB) and apoptosis-inducing

223 The presence of cytolethal distending toxin was confirmed on the basis of character

224 ), gafD (G fimbriae), cnf1, cdtB (cytolethal distending toxin), cvaC (colicin V), and ibeA (invasion

225 ing subunit B of the H. hepaticus cytolethal distending toxin).

226 ed genes needed for the action of cytolethal distending toxin, including a cell-surface protein that

227 nostic assay: hemolysin E (HlyE), cytolethal distending toxin, S. Typhi lipopolysaccharide (LPS), and

228 ogue of the active subunit of the cytolethal distending toxin, which causes DNA damage leading to cel

229 ell-detaching E. coli (6.9%), and cytolethal distending toxin-producing E. coli (0.9%).

230 verall the pathotypes, apart from cytolethal distending toxin-producing E. coli, were recovered both

231 s and induces apoptotic death via cytolethal distending toxin.

232 bacteria and do not depend on the cytolethal distending toxin.

233 Abbreviations: Cdt, cytolethal distending toxin; CSC, cancer stem cells; HNSCC, head an

234 hich is homologous to a family of cytolethal distending toxins (Cdt) expressed by several Gram-negati

235 hich is homologous to a family of cytolethal distending toxins (Cdt) expressed by several gram-negati

236 hree genes encoding the family of cytolethal distending toxins (Cdt).

237 Cytolethal distending toxins (CDTs) are multisubunit proteins produ

238 Cytolethal distending toxins (CDTs) are tripartite protein exotoxin

239 Cytolethal distending toxins (CDTs) block cell division by arrestin

240 The cytolethal distending toxins (CDTs) compose a subclass of intracell

241 llustrated here for the family of cytolethal distending toxins (CDTs).

242 Cytolethal distending toxins are produced by a small but diverse gr

243 sland that carries genes encoding cytolethal distending toxins.

244 Effective distending transmural pressure (dP(FW)) and transseptal

245 osomes that become aberrantly elongated into distended tubules.

246 Clinical examination revealed a distended tympanic abdomen with generalized tenderness b

247 The stomach has a significant capacity to distend (up to 2-4 L of food) and malignant gastric outl

248 ZAP1 mutants lacked the flocculence and distended vacuoles characteristic of zinc-deficient cell

249 notably enriched in the intima and media of distended veins.

250 ronary development, including dysmorphic and distended vessels along the atrioventricular groove and

251 lood sludging, boxcar blood flow phenomenon, distended vessels, damaged vessels, hemosiderin deposits

252 With the nasooropharynx adequately distended with air, the normal cervicocranial prevertebr

253 g microelectrode array while the stomach was distended with an implanted balloon.

254 The pancreas (or pancreatic limb) was distended with collagenase solution, and digested using

255 The adjacent segment of gut was distended with fluid.

256 zed neuropathologically by ballooned neurons distended with lipid storage, axonal spheroid formation,

257 physical examination, the abdomen was mildly distended with moderate tenderness.

258 njection, and frozen slices containing ducts distended with murine ductal carcinoma in situ (DCIS) we

259 In addition, the large intestinal loops were distended, with colonic mucosa exhibiting an aberrant gr

260 the ER in Lman1(-/-) hepatocytes is slightly distended, with significant accumulation of alpha1-antit