ライフサイエンスコーパス: diversify

1 ce the natural ability of trees to adapt and diversify.

2 function and cell morphology can evolve and diversify.

3 o explore how closely related neuronal types diversify.

4 servation measures, are likely to extend and diversify.

5 receptor complex have both been expanded and diversified.

6 biological outcomes of phosphoinositide are diversified.

7 e is conserved, compensation mechanisms have diversified.

8 ng material, and the products can be readily diversified.

9 n the Andaman Archipelago could have further diversified.

10 t how these complex traits are assembled and diversified.

11 men and is increasing over time as the field diversifies.

12 olinyl sulfones with a range of structurally diversified 1 degrees , 2 degrees , and 3 degrees alcoho

13 uted piperidines with arylaldehydes provides diversified 3,5-diarylmethylpyridines in high to excelle

14 This method was used to diversify a heterologous beta-carotene biosynthetic path

15 origin in the early Cretaceous, grasses have diversified across every continent on Earth, with a hand

16 Diversified agricultural landscapes can enhance the biod

17 Diversifying agricultural landscapes may mitigate biodiv

18 d communities were evident in intensive- and diversified-agricultural habitats, but were strongest in

19 These findings demonstrate that diversified agriculture can help to alleviate the long-t

20 n bird communities in intensive-agriculture, diversified-agriculture and natural-forest habitats in 4

21 atibility (SI) is a spectacular example of a diversified allelic series in which numerous highly dive

22 ovided by studies of Drosophila melanogaster diversifying along the thermal gradient in Evolution Can

23 Oak lineages have diversified among geographic regions, followed by ecolog

24 markably similar to financial hedging, where diversifying an investment portfolio protects against ec

25 As lineages diversify, an early and often rapid phase of species and

26 ow complex traits of multiple functions have diversified and codiversified across interacting lineage

27 ice colonized with a single CFU, VRE rapidly diversified and expanded into distinct lineages that com

28 Hanseniaspora is an ancient lineage that has diversified and thrived, despite lacking many otherwise

29 Marine tetrapods quickly diversified and were established as marine top predators

30 ever, the extent to which commensal bacteria diversify and adapt within the human gut remains unclear

31 e of nascent allopolyploidy, can exacerbate, diversify and perpetuate the effects of allopolyploidiza

32 s the applications of CRISPR-Cas9 technology diversify and spread beyond the laboratory to diagnostic

33 Cytosine modifications diversify and structure the genome thereby controlling p

34 tock collections, especially those involving diversified animals, face some unique challenges that ma

35 interactions among the electrolytes and the diversified anode and cathode chemistries therein.

36 recombination (CSR) alters the Ig isotype to diversify antibody effector functions.

37 nd strand breaks that inactivate viruses and diversify antibody repertoire.

38 Pyronaridine-artesunate can be used to diversify antimalarial therapy in areas of artemisinin-r

39 nition of "cold" tumors, resulting in a more diversified antitumor T-cell response, yet RT alone rare

40 tric potential gating on the FET and explore diversified applications of electric double layer FETs (

41 We also find that a diversified approach is critical.

42 a slower-evolving lineage (SEL), which began diversifying approximately 54 mya.

43 a faster-evolving lineage (FEL), which began diversifying approximately 87 million years ago (mya), a

44 antitative antimicrobial use across a highly diversified aquaculture industry is not well characteriz

45 mmon ancestor of tetrapods and bony fish and diversified as multigene families independently in the t

46 miological evidence that the HIV pandemic is diversifying at country level and highlights the increas

47 miological evidence that the HIV pandemic is diversifying at country level and highlights the increas

48 araptor), suggests dromaeosaurids were still diversifying at the end of the Cretaceous.

49 minal center, create an affinity-restricted, diversified B cell repertoire for rapid plasma blast res

50 jor lineages of testate amoebae were already diversified before the Sturtian glaciation (720 mya), su

51 e as an engine for the production of new and diversified bioactive polyketides in an automated, rapid

52 tion enhances CD8(+) T cell participation in diversifying both antigenicity and the kinetics of pepti

53 s demonstrate the human SCF enzyme system is diversified by association with multiple catalytic enzym

54 o prepare advanced intermediates that can be diversified by glycosyltransferases in a branch-selectiv

55 8 iGluR receptor subunits, many of which are diversified by splicing and RNA editing, localize to >20

56 erved in gene content and synteny, they have diversified by subgenomic transposon exchanges that equi

57 lectronic and optical properties are greatly diversified by the buckled lattice structure, stacking c

58 ,5), and growing populations of cells in CLL diversify by stochastic changes in DNA methylation known

59 erpene synthases generate terpenes employing diversified carbocation chemistry, including highly spec

60 This study on VvAHGD sheds light on the diversified catalytic mechanisms and evolution of NAD(P)

61 Stochastic mechanisms diversify cell fate in organisms ranging from bacteria t

62 remodeling of their myelination profiles to diversify circuit tuning in response to sensory experien

63 tency of several types of hPSCs using a more diversified clade of mammals, the ungulates.

64 ortant members of the sphingolipid family, a diversified class of bioactive molecules that mediate ma

65 d-of-care therapies and persist in patients, diversify clonally and serve as reservoirs to drive rela

66 (n = 11 729) set of MRI scans from a highly diversified cohort spanning different studies, scanners,

67 ace plasmon resonance (SPR), we present this diversified collection to collagen and quantify the kine

68 and North America, we show that disturbance diversifies communities when dispersal is limited, but h

69 This diversified compensatory profile was associated with lar

70 The ligand-templated assembly can be used to diversify CQD crystal architectures to guide formation o

71 Determining where species diversify (cradles) and persist (museums) over evolution

72 omatography (HPLC) data for these late-stage diversified cyclic RGD peptides and to further character

73 roscience research to date, will enlarge and diversify databases and pave the way for clinical and di

74 o, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dog

75 ble branching mechanism is key to define and diversify dendrite arbor compartmentalization.

76 y to generate mutant knockout collections or diversify DNA sequences.

77 Rossmann-like fold is the most prevalent and diversified doubly-wound superfold of ancient evolutiona

78 effector interactions, with the potential to diversify downstream responses.

79 unicellular organisms are already naturally diversified due to the inherent stochasticity of biologi

80 t the least because they evolved and rapidly diversified during the late Cambrian, a time interval be

81 e that initiates BM formation, which rapidly diversifies during tissue differentiation.

82 y 95% of extant species originated and began diversifying during the middle Eocene, coincident with t

83 iations of both interactions and yields more diversified dynamics.

84 underwent a lineage-specific gene expansion, diversifying early in land plant evolution, potentially

85 Early diversifying efforts show promise in leveling this vast

86 nted strategies could hereby facilitate more diversified end-use of herring by-products from being 10

87 ons include repurposing existing proteins to diversify endocytosis and trafficking, as well as prefer

88 genes encoding a core palette of triterpene-diversifying enzymes, presumably in response to strong e

89 nsive development is a ubiquitous and highly diversified example of phenotypic plasticity, yet its un

90 The EOD has diversified extensively, especially in duration, which v

91 Here, we report the discovery of a diversified family of fish viruses, designated nackednav

92 d gaps, reducing food waste, shifting toward diversified farming, and consuming seasonal produce.

93 ally between habitats, with benthic lineages diversifying faster and colonizing midwater habitats mor

94 dependent upon the presence of functionally diversified fatty acyl desaturase 2 (Fads2) enzymes, sin

95 lineages emerged by the early Oligocene and diversified first in the Hengduan Mountains.

96 uate two axes by which fishers in Alaska can diversify fishing activities.

97 distributive mechanism responsible for both diversifying flux delivery to the shoreline and dampenin

98 findings suggest that cysteine-rich peptides diversified for a variety of specialized functions, incl

99 The millets may be diversified for personalized nutrition and development o

100 00 million years ago and then duplicated and diversified from ancestral genes across the metazoan and

101 how that the presynaptic protein RIM-BP2 has diversified functions in neurotransmitter release at dif

102 le structures with complex architectures and diversified functions.

103 tobacco use patterns continue to change and diversify, future studies need to carefully assess the i

104 ubunits, and variety in subunit combinations diversifies GABAAR functions to tune brain activity.

105 Distinct and diversified genetic mutations emerged in the resistant m

106 As these viruses continue to diversify genetically and antigenically, it is critical

107 knowledge, one of the most comprehensive and diversified genomic libraries in yeast ever reported.

108 rplus, (2) future Co supply will become more diversified geographically and mined more as a byproduct

109 rinciples calculations, including the adatom-diversified geometric structures, the Si- and C-dominate

110 iocene was an important period when Lejeunea diversified globally.

111 nt size fluctuations are sufficient to fully diversify glutamatergic synaptic sizes, with activity-de

112 xozoans (Cnidaria: Myxozoa) are an extremely diversified group of endoparasites some of which are cau

113 Among spiders, taxonomically the most diversified group of terrestrial predators, only a few s

114 ges (molecular HIV clusters) suggests highly diversified HIV transmission networks across Botswana co

115 otential TE domains as biocatalytic tools to diversify HRPKS structures.

116 ny of a single B cell responding to Ag, with diversified Ig receptors.

117 V(D)J recombination assembles and diversifies Ig and T cell receptor genes in developing B

118 ceptor, their viral glycoproteins are highly diversified, impeding efforts to isolate cross-neutraliz

119 reme climate events in isolated refugia, and diversified in benthic environments that became increasi

120 rent genotypes play disparate roles and have diversified in concert with their hosts.

121 between Saccharomyces species originated and diversified in industrial environments by combining key

122 ed box zinc finger protein (KRAB-ZFP) family diversified in mammals.

123 how tRNA, and possibly the genetic code, is diversified in nature.

124 e new, less substituted alkene, which can be diversified in subsequent reactions.

125 mokines and chemokine receptors have rapidly diversified in teleost fish but their immune functions r

126 The findings also showed these two species diversified in the Pliocene to early Pleistocene era, an

127 The major lineages rapidly diversified in warm and wet habits during the Late Creta

128 systems accumulate evolutionary novelty and diversify in the course of evolution is a fundamental pr

129 hozoa suggests other groups will persist and diversify in their wake.

130 e evolution of similar traits in populations diversifying in similar conditions, provides strong evid

131 y buffering alley crops to weather extremes, diversifying income to hedge financial risk, increasing

132 tomes, along with two other subfamilies that diversified independently across protostome phyla.

133 ole in protostome-deuterostome ancestors and diversified independently into several neuron types in a

134 genes among species, potentially reflecting diversified intensity of sexual selection.

135 Animals have diversified into a bewildering variety of morphological

136 hich horses were first domesticated and then diversified into a variety of breeds showing a range of

137 ecies in a geologically short time that have diversified into a variety of ecological niches.

138 that the hsp/hsc70 gene family in Amphipoda diversified into cognate and heat-inducible paralogs ind

139 e monoclonal in origin, and the CRCs further diversified into different subclones with heterogeneous

140 Vs) are genetically highly variable and have diversified into multiple evolutionary lineages that are

141 bodia, the P falciparum KEL1/PLA1 co-lineage diversified into multiple subgroups and acquired new gen

142 species; Brassicaceae, the mustard family), diversified into several well-defined subclades in the v

143 Lemurs have diversified into species with diverse daily activity pat

144 These cells can diversify into a spectrum of states, which might promote

145 ch the environment ("tracking strategy"), or diversify into coexisting phenotypes to cope with enviro

146 ent during which embryonic pluripotent cells diversify into lineage-specific precursors that will gen

147 We show how a single GPCR gene can diversify into several isoforms with distinct signalling

148 is to evolve extreme embolism resistance and diversify into xeric environments.

149 nized the Deccan Plateau and northern India, diversifying into new, more arid habitats after environm

150 em acts as an expressed genetic barcode that diversifies its sequence and that the rate of diversific

151 These were characterized by highly diversified KIR repertoires including late stage NKG2A(-

152 synthases, revealing the ability to produce diversified labdane-related diterpene scaffolds.

153 d the increasing permeability of natural and diversified landscape.

154 (MscS) is the prototype of an evolutionarily diversified large family that fine-tunes osmoregulation

155 ength and root tissue density as angiosperms diversified, largely independent from leaf changes or my

156 s problem by devising syntheses of NP leads, diversifying late-stage intermediates, or derivatizing t

157 ch growing malignant populations genetically diversify, leading to tumour progression, relapse and re

158 This approach has a potential to provide a diversified library of N-containing compounds, starting

159 ptive radiation is the association between a diversifying lineage and the evolution of phenotypic var

160 compared to background levels in more slowly diversifying lineages.

161 cene fossils shows that Solanaceae were well diversified long before final Gondwanan breakup.

162 ator Bdellovibrio bacteriovorus, we report a diversified lysozyme, DslA, which acts, unusually, upon

163 s are primarily free-living, Symbiodiniaceae diversified mainly as symbiotic lineages.

164 ighlight how in vivo imaging has matured and diversified, making it now possible to concurrently moni

165 protein-modifying enzymes that functionally diversify mammalian ribosomes.

166 By diversifying MarathonRT reaction protocols, we provide a

167 r the course of evolution, organism size has diversified markedly.

168 of CNTs to enter various types of cells via diversified mechanisms utilising energy-dependent and/or

169 In view of the possibility of diversifying metabolic routes promoted by fermentation,

170 versatile methylation toolbox for preparing diversified methylated arenes.

171 Features increasing resource types and diversifying microhabitats (admixing of oaks and conifer

172 directly involved in reproductive processes, diversify more rapidly than most other gene categories.

173 were more closely related in mutation space, diversifying more recently than subclones from immune ho

174 The large volume and diversified nanomedicine market, undergoing a rapid grow

175 er to identify transcriptional networks that diversify neuron cell fate.

176 The diversified NF-kappaB transcription factor family has be

177 ymphoid tissues to initiate the formation of diversified NK cell repertoires after birth.

178 lineate how heterogeneity in NK cell avidity diversifies NK cell effector function during antiviral i

179 Finally, heterogeneity in NK cell age diversifies NK cell function, with "older" NK cells exhi

180 Unlike artificially diversified, nonimmunoglobulin alternative scaffolds (e.

181 to the countless possibilities available by diversifying not only the metal, but also the reactivity

182 resent the most complex life-forms that ever diversified on Earth, and their oxygen-sensing mechanism

183 , Cyrtognatha subsequently dispersed to, and diversified on, the other islands of the Greater, and Le

184 rase domains of other family members produce diversified OPS structures.

185 mutations, mutations displaying evidence of diversifying or directional selection, or mutations with

186 innovation, yet underrepresented groups that diversify organizations have less successful careers wit

187 rocycles and embed condensed heterocycles to diversify outcomes and improve pharmacological propertie

188 orthologs, suggesting selective pressure to diversify PAM recognition and supporting expansion of th

189 m are: dedicate a coordinator, offer credit, diversify participation, create a tiered structure, and

190 suggests that the soil MCP was stimulated in diversified perennial agroecosystems.

191 e the dominant contributor to SOC accrual in diversified perennial bioenergy crops.

192 domesticated goldfish strains exhibit highly diversified phenotypes in morphology, the genetic basis

193 Specifically, diversifying plant litter from mono- to mixed-species in

194 , and also 3239 cases and 11,808 controls of diversified populations, pinpoints risk regions of ALS g

195 Its evolution is largely driven by diversifying positive selection so that relative fitness

196 ning distinct Ca(2+) channel-SV topographies diversifies Pr in the terminal, thereby establishing a m

197 This precursor could lead to the diversified products when the reaction was carried out u

198 ultilevel, multistakeholder involvement, (3) diversified programming, and (4) social participation an

199 for aggregating compounds with structurally diversified properties compared with the use of a single

200 importance of RNA recoding as a strategy for diversifying proteins, particularly those associated wit

201 ource of evolutionary novelty in this highly diversified receptor-ligand system.

202 S1FG3 has a diversified repertoire of genes associated with Nonribos

203 unction both coordinately and divergently to diversify RNAs.

204 ocessing steps, by insufficiently powered or diversified samples from which typical brain ageing traj

205 ows examination of microbial motion within a diversified, secluded and yet microscopically tractable

206 This study aimed to test the hypothesis that diversifying selection across precipitation gradients, a

207 Here, we hypothesize that diversifying selection also has another manifestation: t

208 cted by the reduction in population size and diversifying selection at multiple sites in the viral ge

209 e sweeps are further supported by signals of diversifying selection enriched in genes involved in res

210 nd induce its degradation; in turn, positive diversifying selection has been observed in regions boun

211 We show that diversifying selection in pathways associated with human

212 We document evidence of diversifying selection in three of six PLVA genomes from

213 On the other hand, a possible case of diversifying selection of the virus was observed in less

214 gest that seed mass in sorghum was shaped by diversifying selection on drought stress, and can inform

215 Evidence for signatures of recent diversifying selection on our identified noncoding loci

216 cles as specialization in herbivores imposes diversifying selection on plant chemical defenses.

217 ility among prochlorosins is the result of a diversifying selection process that favors large, rather

218 t genes on sex chromosomes are under greater diversifying selection than autosomal and organellar gen

219 ave hypervariable positions, which are under diversifying selection, closely adjacent to highly conse

220 hile MHC-DRB was found to be under positive, diversifying selection, MHC-DOB was found to be under pu

221 f purifying selection but little evidence of diversifying selection, with substitution rates comparab

222 d sites exhibiting signal for directional or diversifying selection.

223 tterns at positions subject to purifying and diversifying selections.

224 Synthetic immunology approaches further diversified SMOC activities, as we created interferon- o

225 To generate diversified SMs that enable different functions, SM-codi

226 as benefits, and this tradeoff can result in diversified social roles in groups.

227 y assumed to be conserved, unlike the highly-diversified specialized metabolism, primary metabolic pa

228 included multiple stakeholders, implemented diversified strategies, and fostered critical awareness

229 acylhydrazone two-dimensional (2D) COFs with diversified structures (six examples) under open and sti

230 ]CO(2) and [(11)C]CH(3)I into molecules with diversified structures.

231 ological variation into study design through diversifying study samples and conditions.

232 s species complex, and across the entire and diversified subphylum of Saccharomycotina.

233 cular glands, which therefore originated and diversified subsequently during their evolutionary histo

234 Purposive selection was used to diversify surgeons interviewed across multiple dimension

235 nongenetic variability in bacterial adhesion diversifies susceptibility to infection, both among host

236 als and agrochemicals as well as the one-pot diversified synthesis of fluorinated compounds.

237 It was observed that a fully diversified T cell repertoire could be generated by a li

238 show that recombination plays little role in diversifying T. vivax VSG sequences.

239 the killing efficiency of NK cells with the diversified target recognition of TCRs.

240 , with different adaptor subunits conferring diversified targeting and regulatory functions.

241 y neuron trajectories, whereas temporal fate diversifies terminal elaborations.

242 Next, we diversified the grafted and neighboring CDR sites using

243 receptor usage spatiotemporally controls and diversifies the effects of guidance cues in the adult br

244 C-S bond-cleavage reaction catalyzed by IslA diversifies the known repertoire of GRE superfamily enzy

245 through hosts with distinct PrP(C) sequences diversifies the PrP(CWD) conformations and causes a shif

246 ne deamination, known as A-to-I RNA editing, diversifies the transcriptome and modulates the innate i

247 onal mechanism mediated by ADAR enzymes that diversifies the transcriptome by altering selected nucle

248 ectively acting to overwrite, fine-tune, and diversify the complement of transporters present in a ge

249 ogy can serve as an evolutionary strategy to diversify the function of the regulators that control em

250 sion can easily be tuned, which will greatly diversify the number of applications of DPPs in upconver

251 ucidate structure-activity relationships and diversify the pyrimidinone scaffold, we report a concise

252 Such approaches will be useful to diversify the range of sample preparation schemes and an

253 erent limits to clonal expansion that act to diversify the T cell response repertoire.

254 Hydrazone-doped liquid crystal systems thus diversify the toolbox available to the field of light-ad

255 Data augmentation was implemented to diversify the training data set in a ratio of 10:1.

256 insertions are responsible for rewiring and diversifying the Caenorhabditis HSR.

257 in avoiding clonal senescence, primarily by diversifying the cellular population.

258 utation approach offers a powerful means for diversifying the chemogenetics toolbox to benefit the bu

259 These results indicate that diversifying the corn-soybean rotation that dominates th

260 se the chance of evading turbulent layers by diversifying the direction of migration within the popul

261 robiological data and highlight the need for diversifying the field in order to disentangle the compl

262 earrangement of synthetic yeast chromosomes, diversifying the genotype of millions of Saccharomyces c

263 nomic value of biomass might be amplified by diversifying the range of target products that are synth

264 t regulate viral replication is important in diversifying the resources available to control WNV.

265 h analytes interact with plasmonic surfaces, diversifying the resulting SERS fingerprints.

266 There is significant interest in diversifying the structures of polyketides to create new

267 de testing the device on a larger sample and diversifying the type of stimuli to account for negative

268 Mature B cells diversify their antibody genes by class switch recombina

269 Developing lymphocytes diversify their antigen receptor (AgR) loci by variable

270 d templated mutations via gene conversion to diversify their expressed Ig loci, whereas mice and huma

271 Moreover, exactly how and when neurons diversify their function during development is unknown.

272 xopeptidases that rely on oligomerization to diversify their functional roles.

273 ises when uniform fields of progenitor cells diversify their molecular fate while adopting higher-ord

274 ggests that the effects of guidance cues are diversified, therefore expanding the number of responses

275 nucleophiles or hetero-dinucleophiles in the diversified thiazolylidene ring assembly.

276 antial funding or specialized training, thus diversifying this scientific community.

277 Like other herpesviruses, EBV has diversified through both coevolution with its host and g

278 BCR sequences diversify through mutations introduced by purpose-built

279 d whether the range of novel fuel types that diversified throughout the Cretaceous also altered fire

280 resented in Bacteroidetes and appear to have diversified to access ribose from a variety of substrate

281 cting on DNA and how chromatin proteins have diversified to carry out evolutionarily recent functions

282 e product is prepared on gram scale and then diversified to eight 1,2,3-trifunctionalized building bl

283 conserved, whereas the adjacent position is diversified to fit different glycosidic linkages and mon

284 LRR-RLKs have diversified to hundreds of genes in many plant genomes.

285 icyclic gamma-lactone products can be easily diversified to other medicinally important scaffolds, wh

286 n activator and also shows that MAPKs can be diversified to recognize unique phosphorylation motifs.

287 imple chaperone-titration mechanism produces diversified transcriptional output in response to distin

288 A search for structurally diversified Tyk2 JH2 ligands from 6 (BMS-986165), a pyri

289 ns represent cost-effective opportunities to diversify urban water supplies.

290 by enabling continued growth of anatomically diversifying vascular plants in dehydrative conditions,

291 Unilateral fistulas (10-55.5%) showed more diversified venous drainage pattern than bilateral ones

292 focusing on how these cells have evolved and diversified via natural selection promoting serine prote

293 Cellular states diversify when clonal three-dimensional (3D) spheroids a

294 iota structure and function had expanded and diversified with demonstrable body site specificity (P <

295 2-halo(Br/Cl)-3-arylthio indole was smoothly diversified with privileged heterocycle triazole to prov

296 ification of microbial lineages that have co-diversified with their hosts.

297 er, recently this investment has become less diversified, with a larger fraction of grant dollars in

298 and function had substantially expanded and diversified, with the body site serving as the primary d

299 organization; 3) supporting the growth of a diversifying workforce in epidemiology; and 4) increasin

300 opment, pluripotent cells rapidly divide and diversify, yet the regulatory programs that define the c