ライフサイエンスコーパス: diverticulitis

1 ardized colon resection ratios for recurrent diverticulitis.

2 low-up, we identified 1063 incident cases of diverticulitis.

3 etent patients with mild acute uncomplicated diverticulitis.

4 ary fiber is implicated as a risk factor for diverticulitis.

5 ercutaneous interventions, or admissions for diverticulitis.

6 arely, a colon malignancy is misdiagnosed as diverticulitis.

7 2) antibiotic prescription claims related to diverticulitis.

8 395,838 were cholecystitis, and 412,163 were diverticulitis.

9 e, 18-64 years) with incident, uncomplicated diverticulitis.

10 acute appendicitis, acute cholecystitis, and diverticulitis.

11 xposure in relation to risk of admission for diverticulitis.

12 tigated the association between UV light and diverticulitis.

13 heir number of publications related to acute diverticulitis.

14 ery department with the diagnosis of jejunal diverticulitis.

15 e measure for comparing strategies for acute diverticulitis.

16 ed for patients after emergent admission for diverticulitis.

17 aroscopic lavage for treatment of perforated diverticulitis.

18 a role for vitamin D in the pathogenesis of diverticulitis.

19 of circulating vitamin D are associated with diverticulitis.

20 surgical treatment strategies in complicated diverticulitis.

21 nds among 226 522 nonelective admissions for diverticulitis.

22 statement related to the management of acute diverticulitis.

23 nationally regarding the management of acute diverticulitis.

24 (>5 mm) and/or fat stranding consistent with diverticulitis.

25 superior to placebo in preventing recurrent diverticulitis.

26 and evidence-based advice for management of diverticulitis.

27 ality of life of patients with uncomplicated diverticulitis.

28 2) who also underwent surgical treatment for diverticulitis.

29 older than 18 years with acute uncomplicated diverticulitis.

30 the TNFSF15 gene is associated with surgical diverticulitis.

31 n selected patients with uncomplicated acute diverticulitis.

32 has been proven to prevent the recurrence of diverticulitis.

33 successful nonoperative management of acute diverticulitis.

34 d at the time of sigmoidectomy for recurrent diverticulitis.

35 leostomy over HP in patients with perforated diverticulitis.

36 rform colonoscopy after a diagnosis of acute diverticulitis.

37 er (SERT) which is also seen following acute diverticulitis.

38 dditional risk factors we evaluated included diverticulitis.

39 and 33,500 patients operated electively for diverticulitis.

40 erative treatment of recurrent mild/moderate diverticulitis.

41 nut and popcorn consumption and the risk of diverticulitis.

42 pelvic abscess in a patient with perforated diverticulitis.

43 or poor outcomes if they develop complicated diverticulitis.

44 A compared with patients with >2 episodes of diverticulitis.

45 foration patients who died had no history of diverticulitis.

46 onoscopy following hospitalisation for acute diverticulitis.

47 tients as appendicitis, and four patients as diverticulitis.

48 e, can also contribute to the development of diverticulitis.

49 s with CT-diagnosed uncomplicated left-sided diverticulitis.

50 e differ between individuals with vs without diverticulitis.

51 second treatment encounter for uncomplicated diverticulitis.

52 rs67153654-A: P=3.0 x 10(-11), OR=0.82) with diverticulitis.

53 included, of whom 40,496 had a diagnosis of diverticulitis.

54 The primary end point was incident diverticulitis.

55 dietary interventions for the prevention of diverticulitis.

56 and treatment on the colon cancer rate after diverticulitis.

57 atterns are associated with risk of incident diverticulitis.

58 that are predictive of recurrence of colonic diverticulitis.

59 e diverticulae become inflamed, resulting in diverticulitis.

60 ibute to colonic dysmotility associated with diverticulitis.

61 cer (57%), inflammatory bowel disease (20%), diverticulitis (10%), and benign polyp disease (5%).

62 eatment beyond that necessary for perforated diverticulitis (12 in the laparoscopic lavage group vs 1

63 he 210,268 patients admitted emergently with diverticulitis, 179,649 (85%) were managed medically at

64 sease (5,426 cases) and its more severe form diverticulitis (2,764 cases).

65 diverticulitis (4.3%) and the group without diverticulitis (2.3%) differed significantly (P < 0.001)

66 trol cohort of patients having no history of diverticulitis (26 female).

67 incidence of colon cancer in the group with diverticulitis (4.3%) and the group without diverticulit

68 Other complications included diverticulitis (5), pancreatitis (4), peptic ulcer disea

69 ection (8%; 2%), nephrotoxicity (2%; 0), and diverticulitis (6%; 2%).

70 mpetent patients having at least 1 claim for diverticulitis, 6.4% (n = 5604) underwent a resection.

71 ears and 58.9% female) were hospitalized for diverticulitis (72.2% emergent/urgent).

72 -UV areas, low-UV areas had a higher rate of diverticulitis (751.8 vs 668.1 per 100 000 admissions; P

73 Patients with suspected perforated diverticulitis, a clinical indication for emergency surg

74 geographic variation in colon resection for diverticulitis, a discretionary surgical intervention.

75 sent a 67-year-old male patient with jejunal diverticulitis accompanying with abdominal pain and vomi

76 sks of readmission and emergency surgery for diverticulitis, accounting for death and elective colect

77 Acute diverticulitis accounts for 152,000 hospitalizations in

78 sure is associated with an increased rate of diverticulitis admissions and greater seasonal variation

79 We identified nonelective diverticulitis admissions in the Nationwide Inpatient Sa

80 l thickness and subjective severity of acute diverticulitis allow prediction of recurrent diverticuli

81 Diverticulitis also was a strong risk factor (hazard rat

82 ivariable RR of 1.62 (95% CI, 1.23-2.14) for diverticulitis and 1.91 (95% CI, 1.26-2.90) for divertic

83 ivariable RR of 1.56 (95% CI, 1.18-2.07) for diverticulitis and 1.96 (95% CI, 1.30-2.97) for divertic

84 We documented 939 cases of diverticulitis and 256 cases of diverticular bleeding du

85 95% confidence interval [CI], 1.08-2.94) for diverticulitis and 3.19 (95% CI, 1.45-7.00) for divertic

86 We documented 801 incident cases of diverticulitis and 383 incident cases of diverticular bl

87 follow-up, there were 801 incident cases of diverticulitis and 383 incident cases of diverticular bl

88 95% confidence interval [CI], 1.05-1.47) for diverticulitis and a HR of 1.70 (95% CI, 1.21-2.39) for

89 of the sigmoid colon chronically affected by diverticulitis and adjacent non-affected tissue.

90 ossible confounders, the association between diverticulitis and cancer remained significant with an o

91 In patients with a history of diverticulitis and chronic symptoms, alternative diagnos

92 To investigate the association between diverticulitis and colon cancer in a large, nationwide c

93 es have investigated the association between diverticulitis and colon cancer with inconclusive result

94 a strong association between development of diverticulitis and colon cancer.

95 olon cancer compared with those without both diverticulitis and colonoscopy with an OR of 2.72 (95% C

96 nfluence of aspirin and NSAID use on risk of diverticulitis and diverticular bleeding in a large pros

97 AIDs is associated with an increased risk of diverticulitis and diverticular bleeding.

98 st circumference, and waist-to-hip ratio and diverticulitis and diverticular bleeding.

99 p ratio significantly increased the risks of diverticulitis and diverticular bleeding.

100 cted can manifest clinical syndromes, mainly diverticulitis and diverticular haemorrhage.

101 itis (seven), abdominal abscess (three), and diverticulitis and esophagitis (one each)], and dentitio

102 2366 of 3165 patients hospitalized for acute diverticulitis and followed up for 8.9 years, only 13.3%

103 s consensus related to many aspects of acute diverticulitis and identifies other areas in need of res

104 cohort study of 46,295 men who were free of diverticulitis and known diverticulosis in 1986 (baselin

105 diverticulitis allow prediction of recurrent diverticulitis and may be useful for stratifying patient

106 e all ddAC (febrile neutropenia [FN], n = 2; diverticulitis and neutropenia, n = 1; and social/econom

107 status quo regarding the treatment of acute diverticulitis and provides important direction for futu

108 of patients with uncomplicated left colonic diverticulitis and to analyze differences in quality of

109 aims to determine the long-term outcomes of diverticulitis and to apply the findings to current prac

110 ase our understanding of the pathogenesis of diverticulitis and to clarify treatment algorithms.

111 variation in elective sigmoid resection for diverticulitis and to identify factors associated with o

112 Among patients with likely perforated diverticulitis and undergoing emergency surgery, the use

113 ity of life (QoL) in patients with recurring diverticulitis and/or ongoing complaints.

114 vative management in patients with recurring diverticulitis and/or ongoing complaints.

115 rtmann procedure", OR "sigmoidectomy"), AND "Diverticulitis", AND "Peritonitis" AND "therapeutic irri

116 ived by 267,000 patients admitted with acute diverticulitis, and 33,500 patients operated electively

117 attern was associated with increased risk of diverticulitis, and a prudent pattern was associated wit

118 ng advocacy of primary anastomosis for acute diverticulitis, and nonoperative treatment of recurrent

119 the prevention of colonic diverticulosis and diverticulitis, and support the efficacy of a number of

120 e living in England, including colon cancer, diverticulitis, appendicitis, hernias, varicose veins, d

121 Current practice guidelines for diverticulitis are based on limited evidence.

122 Complications following diverticulitis are difficult to classify because no trad

123 Antecedent episodes of diverticulitis are felt to increase the risk of developi

124 Patients with multiple (>2) episodes of diverticulitis are not at increased risk for poor outcom

125 The long-term morbidity and mortality of diverticulitis are not well defined.

126 increase the risk of developing complicated diverticulitis, as well as its subsequent morbidity and

127 s has been implicated in the pathogenesis of diverticulitis, associations between the microbial ecosy

128 ts underwent an elective colon resection for diverticulitis at 2462 hospitals over the study period.

129 r observational study of patients with acute diverticulitis at a safety-net hospital.

130 g elective colon resection for uncomplicated diverticulitis because of uncertain effectiveness at red

131 g with CT-diagnosed uncomplicated left-sided diverticulitis between 2014 and 2017 were identified.

132 cutive subjects diagnosed with acute colonic diverticulitis between January 2004 and May 2008 to dete

133 Of the 1497 patients with uncomplicated diverticulitis, cancer was found in 5 (proportional esti

134 ient, and antibiotic prescription claims for diverticulitis captured in the MarketScan (Truven Health

135 f our knowledge and treatment of complicated diverticulitis (CD) are based on outdated literature rep

136 hese positions, appendicitis may mimic acute diverticulitis, cholecystitis, duodenal ulcer, duodeniti

137 After considering all types of diverticulitis claims, 56.3% (1720 of 3054) of elective

138 d electronic medical record data obtained on diverticulitis colectomy patients across a Healthcare Ne

139 99 patients undergoing colonic resection for diverticulitis, colorectal cancer (CRC), benign neoplasm

140 hazard ratio of 1.55 (95% CI, 1.20-1.99) for diverticulitis compared to men in the lowest quintile.

141 t between patients with multiple episodes of diverticulitis compared with those with 1 or 2 prior att

142 ight not be necessary for some patients with diverticulitis complicated by abscess.

143 In uncomplicated diverticulitis, consensus was reached regarding appropri

144 Elective resection for uncomplicated diverticulitis decreases the risk of recurrence, still 6

145 g complaints (>3 months) after an episode of diverticulitis, demonstrated a significantly higher QoL

146 hould have a colonoscopy after an episode of diverticulitis depends on the patient's history, most re

147 e questionnaire in 1986 until a diagnosis of diverticulitis, diverticulosis or diverticular bleeding;

148 on resection for patients with uncomplicated diverticulitis, early surgery (after <3 preceding episod

149 netic risk profiling, practice improvements, diverticulitis, enhanced recovery protocols, fecal incon

150 c obstructive pulmonary disease, chest pain, diverticulitis, enterovesical fistula, gastroenteritis,

151 eviously considered after a second confirmed diverticulitis episode, is being increasingly deferred.

152 of 46.6% had a history of at least one prior diverticulitis episode, whereas 53.4% presented with CD

153 d patients, 27,450 (16.3%) suffered a second diverticulitis episode.

154 analysis: group A = those with 1 or 2 prior diverticulitis episodes (n = 118) versus group B = patie

155 leeding) or the number of previously treated diverticulitis episodes for patients undergoing elective

156 cognition of "smoldering" (or nonrecovering) diverticulitis episodes.

157 The top 5 acute diverticulitis experts in 5 international geographic reg

158 survey website was used and a panel of acute diverticulitis experts was formed via the snowball metho

159 e cholecystitis (F = 37.13, P < 0.0001), and diverticulitis (F = 69.90, P < 0.0001).

160 tional guidelines for treatment of recurrent diverticulitis fail to offer strong recommendations for

161 from a single family with surgically managed diverticulitis [familial diverticulitis (FD), 4 female,

162 surgically managed diverticulitis [familial diverticulitis (FD), 4 female, mean age = 51.1 +/- 7] we

163 netic factors may play a significant role in diverticulitis, few genes have yet been implicated in di

164 er hospitalisation with CT-proven left-sided diverticulitis for the first time in a UK population.

165 omized trials of patients with uncomplicated diverticulitis found that antibiotics did not speed reco

166 nt treated for >=2 episodes of uncomplicated diverticulitis from a nationwide commercial claims datas

167 osis and management of chronic and recurrent diverticulitis from January 1, 2000, to March 31, 2013.

168 nths) and/or frequently recurring left-sided diverticulitis (>2 episodes in 2 years) after an objecti

169 vative management in patients with recurring diverticulitis (>2 episodes within 2 years) and/or ongoi

170 The incidence of diverticulitis has been associated with geographic and s

171 Peritonitis secondary to perforated diverticulitis has conventionally been managed by resect

172 Consensus regarding the treatment of diverticulitis has evolved over time, with increasing ad

173 Approximately 20% of patients with incident diverticulitis have at least 1 recurrence.

174 Patients with diverticulitis have high surgical site infection rates d

175 s; inflammatory bowel disease; incontinence; diverticulitis; hemorrhoids; fistulas; and quality impro

176 ge as treatment for patients with perforated diverticulitis Hinchey III was feasible and safe in the

177 nn's procedure as a treatment for perforated diverticulitis (Hinchey III or Hinchey IV disease).

178 cy of mesalamine in preventing recurrence of diverticulitis in 2 identical but separate phase 3, rand

179 ne vs placebo in the prevention of recurrent diverticulitis in 590 (PREVENT1) and 592 (PREVENT2) adul

180 aged nonoperatively after a first episode of diverticulitis in Ontario, Canada (2002-2012).

181 e multi-generational family with early onset diverticulitis in order to identify a genetic component

182 point-of-care ultrasonographic diagnosis of diverticulitis in the emergency department.

183 ) adult patients with >/=1 episodes of acute diverticulitis in the previous 24 months that resolved w

184 t dramatic changes in rates of treatment for diverticulitis in the United States.

185 ant seasonal variation, with a lower rate of diverticulitis in the winter (645 per 100 000) compared

186 Routine colonoscopy following acute diverticulitis in this cohort did not identify a single

187 atabase identified all patients admitted for diverticulitis in Washington State (1987-2012).

188 all annual age-adjusted admissions for acute diverticulitis increased from 120,500 in 1998 to 151,900

189 t recommended for average-risk patients with diverticulitis, irrespective of the number of episodes o

190 Diverticulitis is a chronic disease of the colon in whic

191 Diverticulitis is a common disease, especially in the We

192 Diverticulitis is a focal asymmetric process with fascia

193 Colonic diverticulitis is a painful gastrointestinal disease tha

194 Diverticulitis is a prevalent gastrointestinal disorder

195 The pathophysiology of diverticulitis is associated with altered gut motility,

196 Our understanding of complicated diverticulitis is based on outdated literature.

197 al therapy for SUDD and to prevent recurrent diverticulitis is being actively investigated.

198 uld be educated that the risk of complicated diverticulitis is highest with the first presentation.

199 ically proven episode of acute uncomplicated diverticulitis is low.

200 the mortality and morbidity from complicated diverticulitis is needed.

201 h elective colectomy following 2 episodes of diverticulitis is no longer accepted.

202 The natural history of uncomplicated diverticulitis is often benign.

203 definition of uncomplicated and complicated diverticulitis is provided.

204 er recovery from an uncomplicated episode of diverticulitis is rare (<5%) and that age at onset young

205 A role for a genetic predisposition in diverticulitis is suggested by its association with here

206 In cases of diverticulitis it should be kept in mind that in patient

207 used in the management of Hinchey grade III diverticulitis leads to more reinterventions within 30 d

208 The choice of operation for perforated diverticulitis lies between HP and PRA.

209 surgical techniques, complex anal fistulas, diverticulitis, local excision techniques for rectal neo

210 ter computed tomography-proven uncomplicated diverticulitis may be low.

211 rticulitis, routine colonic evaluation after diverticulitis may represent a nonessential burden on he

212 The elective colectomy rate for diverticulitis more than doubled, without a decrease in

213 Results Colonic diverticulitis most commonly involved the rectosigmoid (

214 aspirin NSAIDs also had an increased risk of diverticulitis (multivariable HR, 1.72; 95% CI, 1.40-2.1

215 cores were associated with decreased risk of diverticulitis (multivariate hazard ratio, 0.74; 95% CI,

216 (n = 115), perforating appendicitis (n = 6), diverticulitis (n = 16), tubo-ovarian inflammation (n =

217 for postoperative fluid collection (n = 3), diverticulitis (n = 2), or perforating appendicitis (n =

218 actors driving early, elective resection for diverticulitis need to be determined.

219 54) of elective resections for uncomplicated diverticulitis occurred after fewer than 3 episodes.

220 Perforated diverticulitis occurred more often in group A compared w

221 Diverticulitis of the sigmoid colon is an increasingly c

222 derwent elective resection for uncomplicated diverticulitis, of whom 55.6% (n = 1699) were male.

223 tal questionnaires to men reporting incident diverticulitis on biennial follow-up questionnaires.

224 gery or conservative management of recurring diverticulitis/ongoing symptoms results in a higher qual

225 tions were seen between corn consumption and diverticulitis or between nut, corn, or popcorn consumpt

226 We identified men with diverticulitis or diverticular bleeding based on respons

227 tic disease with complications such as acute diverticulitis or diverticular haemorrhage.

228 to people who did not have a registration of diverticulitis or diverticulosis.

229 ion received glucocorticoids, had antecedent diverticulitis, or both.

230 ore urgent pathologies such as appendicitis, diverticulitis, or malignancies.

231 Eighty-five percent of emergent diverticulitis patients do not recur after initial medic

232 4 in 148 non-familial and unrelated sporadic diverticulitis patients identified two additional rare v

233 ACDiT tool was successfully applied to acute diverticulitis patients managed operatively and nonopera

234 resection should be strongly considered for diverticulitis patients older than 50 years or those who

235 life-threatening acute complications such as diverticulitis, perforation, intestinal hemorrhage and o

236 Therefore, during pancreatitis, unlike diverticulitis, PNLIP leaking into visceral adipose tiss

237 nally, elective 'prophylactic' surgery after diverticulitis, previously considered after a second con

238 ery are low after nonoperative management of diverticulitis, providing evidence for the practice of d

239 es pertaining to diagnosis and management of diverticulitis published between January 1, 2000, and Ma

240 onship of medical or surgical treatment with diverticulitis recurrence and/or receipt of an ostomy.

241 Mesalamine did not reduce the rate of diverticulitis recurrence at week 104.

242 Diverticulitis recurrence was defined as surgical interv

243 Predictors of diverticulitis recurrence were assessed with univariate

244 ivariate analysis, significant predictors of diverticulitis recurrence were determined to be maximum

245 significantly worse outcomes associated with diverticulitis recurrence, resection should be strongly

246 ciations between the microbial ecosystem and diverticulitis remain largely unstudied.

247 T-cell maturation, in the pathophysiology of diverticulitis requiring surgery.

248 tand that genetic factors also contribute to diverticulitis risk.

249 Elective operations for diverticulitis rose from 16,100 to 22,500 per year durin

250 widespread computed tomographic scanning for diverticulitis, routine colonic evaluation after diverti

251 The SNP discovered to be associated with diverticulitis (rs7848647) was then confirmed in a separ

252 he gefitinib group (related to sigmoid colon diverticulitis/rupture complicated by pneumonia).

253 ry phase of this study, 21 sporadic surgical diverticulitis (SD) patients (9 female, mean age = 52 +/

254 Patients with diverticulitis should undergo endoscopic surveillance fo

255 Patients with complicated diverticulitis still have a significant risk of colorect

256 t standard management of acute uncomplicated diverticulitis still is hospital admission both in Europ

257 Complications of diverticulitis, such as abdominal sepsis, are less likel

258 Create and validate diverticulitis surgical site infection prediction scale.

259 e patient-reported frequency and severity of diverticulitis symptoms.

260 rgical intervention for chronic or recurrent diverticulitis than was previously thought necessary.

261 equire urgent surgery for acute, complicated diverticulitis that has not improved with antibiotics pr

262 resection beyond 2 episodes of uncomplicated diverticulitis, the incidence of elective colectomy has

263 d on consideration of the risks of recurrent diverticulitis, the morbidity of surgery, ongoing sympto

264 y for colonic perforation, colonic bleeding, diverticulitis, the postpolypectomy syndrome, or other s

265 For patients undergoing surgery for acute diverticulitis, there was little change over time in the

266 lucocorticoids or had previously experienced diverticulitis, these individuals should be considered a

267 t and lifestyle factors could affect risk of diverticulitis through their effects on the intestinal m

268 mmend routine colonic evaluation after acute diverticulitis to confirm the diagnosis and exclude mali

269 e injury during acute pancreatitis and acute diverticulitis to determine its role in organ failure.

270 mmend elective resection after 2 episodes of diverticulitis to reduce morbidity and mortality.

271 ecommended colon resection for uncomplicated diverticulitis to reduce the risk of recurrence or colos

272 mmend elective resection after 2 episodes of diverticulitis to reduce this morbidity and mortality.

273 group (myocardial infarction [anticipated], diverticulitis [unanticipated], and metabolic surgery [u

274 ents with CT proven uncomplicated left-sided diverticulitis underwent follow-up colonoscopy.

275 in which patients with CT diagnosis of acute diverticulitis underwent surgery, colonoscopy, or barium

276 Perforated colonic diverticulitis usually requires surgical resection, whic

277 o determine an association of TNFSF SNP with diverticulitis versus the control groups.

278 rvention after the first episode of emergent diverticulitis was 0.3% compared to 4.6% for emergent re

279 The association between dietary patterns and diverticulitis was predominantly attributable to intake

280 Complicated diverticulitis was present in 22% (98 of 440) of patient

281 for perforation, obstruction, ulceration, or diverticulitis, was determined.

282 surgical and percutaneous interventions for diverticulitis were calculated and temporal changes asse

283 general peritonitis and suspected perforated diverticulitis were eligible for inclusion if plain abdo

284 Not all patients presenting with suspected diverticulitis were enrolled.

285 Patients with diverticulitis were identified from the registers and ma

286 ography, Ultrasound or Endoscopy) episode of diverticulitis were included in this study.

287 ies of colonic evaluation after proven acute diverticulitis were included.

288 reporting newly diagnosed diverticulosis or diverticulitis were mailed supplemental questionnaires.

289 Patients with Hinchey I or II diverticulitis were not eligible for inclusion.

290 6879 patients with Hinchey III-IV perforated diverticulitis were obtained from two databases (n = 204

291 litis who were hospitalized with complicated diverticulitis were retrospectively analyzed.

292 total of 150 patients with prior episodes of diverticulitis who were hospitalized with complicated di

293 Those with diverticulitis, who had no colonoscopy, had an increased

294 hat laparoscopic lavage may treat perforated diverticulitis with less morbidity than resection proced

295 hout defunctioning ileostomy, for perforated diverticulitis with purulent or faecal peritonitis (Hinc

296 Perforated diverticulitis with purulent peritonitis (Hinchey III) h

297 Perforated diverticulitis with purulent peritonitis has traditional

298 ate treatment of choice for acute perforated diverticulitis with purulent peritonitis.

299 c lavage and sigmoid resection in perforated diverticulitis with purulent peritonitis.

300 ich can become infected and inflamed causing diverticulitis, with potentially severe complications.