ライフサイエンスコーパス: dividing cell

1 align the spindle along the long axis of the dividing cell.

2 as an immortal, slow-cycling, asymmetrically dividing cell.

3 I) in the interphasic cells neighbouring the dividing cell.

4 ssibly resulting in neurodegeneration in non-dividing cells.

5 (7)), interacts with R-loop-enriched loci in dividing cells.

6 tenation also formed the contractile ring in dividing cells.

7 protein aggregates in otherwise unperturbed dividing cells.

8 equently linked to cell cycle transitions in dividing cells.

9 -2'-deoxyuridine (EdU) to profile individual dividing cells.

10 in filaments that facilitates cytokinesis in dividing cells.

11 se 1 expression, which is higher in actively dividing cells.

12 macromolecular synthesis demands of rapidly dividing cells.

13 itate stable propagation of tau pathology in dividing cells.

14 those prevailing either in cycling or in non-dividing cells.

15 ected cells and by maintaining its genome in dividing cells.

16 DNA damage supports the genomic integrity of dividing cells.

17 CenH3 pool and replenish CenH3 chromatin in dividing cells.

18 elivering the viral genome to the nucleus of dividing cells.

19 inding to SAMHD1 expression and stability in dividing cells.

20 replacement histone genes in long-lived non-dividing cells.

21 ssing the effects of small molecule drugs in dividing cells.

22 bryos generate a cap in other asymmetrically dividing cells.

23 bolic and energetic demands of these rapidly dividing cells.

24 d stability of kinetochore-MT attachments in dividing cells.

25 ric segregation of fate determinants between dividing cells.

26 ation of labels incorporated into the DNA of dividing cells.

27 le F-actin for contractile ring formation in dividing cells.

28 opment of gene-targeting applications in non-dividing cells.

29 s are resistant to chemotherapy that targets dividing cells.

30 termini that is recognized by a receptor on dividing cells.

31 vered based on their ability to kill rapidly dividing cells.

32 of motile cells, and the cleavage furrow of dividing cells.

33 h specific chemical structures accumulate in dividing cells.

34 ous accumulation of repeat expansions in non-dividing cells.

35 highly correlated with lipids accumulated in dividing cells.

36 ivation and subsequent F-actin remodeling in dividing cells.

37 parameters from large empirical datasets of dividing cells.

38 abscission even in apparently symmetrically dividing cells.

39 del organisms for studying aging in actively dividing cells.

40 tribution of the G protein RomR within these dividing cells.

41 stems from in vitro studies of continuously dividing cells.

42 d that ultimately affect Z-ring formation in dividing cells.

43 ging chromatin is present, but not in normal dividing cells.

44 -the divisome--that assembles at mid-cell in dividing cells.

45 dGTP or GTP found in either dividing or non-dividing cells.

46 g intracellular redox homeostasis in rapidly dividing cells.

47 s in the SDN-POA displayed the morphology of dividing cells.

48 plus-end-tagging by PRC1 is also observed in dividing cells.

49 the leading edge of constriction furrows in dividing cells.

50 allow transcription in nondividing or slowly dividing cells.

51 the slow changes in impedance of growing and dividing cells.

52 tosis is probably the most iconic process of dividing cells.

53 es replication stress (RS) and DNA damage in dividing cells.

54 gulator of Notch signaling in asymmetrically dividing cells.

55 ecting cell fate decisions in asymmetrically dividing cells.

56 nt and reveal its essential role in actively dividing cells.

57 ls long-range chromosome movement into newly dividing cells.

58 bility, homeostasis and DNA synthesis in non-dividing cells.

59 iffusive path adopted by an inert protein in dividing cells.

60 ry cell fate determination in asymmetrically dividing cells.

61 of membranous filaments connecting pairs of dividing cells.

62 achromosomal DNA minichromosomes in actively dividing cells.

63 et poorly defined roles in proliferating and dividing cells.

64 ablishes order on the micron-length scale in dividing cells.

65 zed PcsB mainly to the septa and equators of dividing cells.

66 strate for this reaction to identify rapidly dividing cells.

67 s widely assumed that tumors arise only from dividing cells.

68 rs is required for proper ER partitioning in dividing cells.

69 th the nuclear envelopes and mitochondria of dividing cells.

70 Ca(2+) signal at the centrosomes of actively dividing cells.

71 remodelling role of Mpp5a is not specific to dividing cells.

72 provide insights into the biology of rapidly dividing cells.

73 d is essential for chromosome segregation in dividing cells.

74 PI3K subunits has been shown to oscillate in dividing cells.

75 intercellular bridge that forms between two dividing cells.

76 duced mitochondrial length characteristic of dividing cells.

77 was evident, suggesting selective purging of dividing cells.

78 ressed genes when comparing to GFP(-) faster-dividing cells.

79 dscape to ensure the epigenomic integrity of dividing cells.

80 emains essential for TAD organization in non-dividing cells.

81 o productively replicate in distinct sets of dividing cells.

82 d an expression pattern confined to actively dividing cells.

83 l anticancer drugs, which compromise rapidly dividing cells.

84 ies of two closely related MAP65 proteins in dividing cells.

85 ing in both symmetrically and asymmetrically dividing cells.

86 a, and a large class with high expression in dividing cells.

87 ts can be unified by a model in which slowly dividing cells accumulate replication-associated DNA bre

88 Thus, our findings demonstrate that, in dividing cells, aggresomes are detrimental over the long

89 The retention of GFP labeling in slowly dividing cells allowed for localization of these cells t

90 Dividing cells almost always adopt a spherical shape.

91 racterize the progression of a population of dividing cells along a branching process.

92 The dividing cells also revealed two rice (Oryza sativa) mic

93 n causes DNA double-strand breaks in rapidly dividing cells, although whether it also affects general

94 r actin networks, and the cleavage furrow of dividing cells--always together with myosin-II.

95 normal presence of lagging chromatin between dividing cells, an evolutionarily conserved abscission/N

96 g of adhesive cell-cell contacts between the dividing cell and its neighbours has profound implicatio

97 3) is co-expressed with Arabidopsis CenH3 in dividing cells and binds directly to both the N-terminal

98 mistry helped to distinguish the subtypes of dividing cells and delineate their locations in the vent

99 the MDM1 protein localizes to centrioles of dividing cells and differentiating multiciliated cells.

100 e repeats during DNA replication in actively dividing cells and during transcription initiation in no

101 have revolutionized our ability to identify dividing cells and follow their fate in various tissues,

102 ajor microtubule organizing center (MTOC) in dividing cells and in many postmitotic, differentiated c

103 nt parvovirus DNA replication that occurs in dividing cells and is independent of cell cycle arrest.

104 stinctions between cytokinetic structures in dividing cells and muscle sarcomeres.

105 OPNR is predominantly expressed in actively dividing cells and performs essential functions in seed

106 ll-to-cell transmission of tau aggregates in dividing cells and possibly neurons.

107 icate that the SAC-RNA CircPVT1, elevated in dividing cells and reduced in senescent cells, sequester

108 to the classic view, most mutations arise in dividing cells and result from uncorrected errors of S-p

109 aphy to image the native structure of intact dividing cells and show that constriction in a variety o

110 opy in samples up to 20 mum thick, including dividing cells and the neuromast organ of a zebrafish em

111 erences in the mechanical properties of live dividing cells and their isolated lipids relative to non

112 ities necessary for [PSI(+) ] propagation in dividing cells and they get diluted out as cells multipl

113 shown to improve knock-in efficiency in non-dividing cells and to harness HDR after direct injection

114 er lentiviruses are capable of infecting non-dividing cells and, therefore, need to be imported into

115 d unique transcriptional signatures of early dividing cells and, unexpectedly, repression of several

116 ities including fewer satellite cells, fewer dividing cells, and an increase in apoptotic cells in KO

117 vels of antiapoptotic Bcl-2 expression, some dividing cells, and clear alkaline phosphatase activity

118 ion of chromosomes during metaphase of 2,572 dividing cells, and developed a software package called

119 function, with fewer satellite cells, fewer dividing cells, and increased apoptotic cells in Mtm1del

120 phosphorylation is low in interphase versus dividing cells, and its levels rise with states of nucle

121 R1) and histone deacetylase 2 in these early dividing cells; and (3) is required for neuronal maturat

122 Mitotically dividing cells appear to be less dependent on translatio

123 labeling and cell sorting, we show that the dividing cells are more susceptible to killing by tobram

124 To this end, researchers monitor changes in dividing cells as they traverse the cell cycle, with the

125 ergetics and biosynthetic demands of rapidly dividing cells as well as to counter a shift in cellular

126 In asymmetrically dividing cells, aster decentration typically follows a c

127 of cells corralling a population of rapidly dividing cells at its center.

128 trically into a population of asynchronously dividing cells at the anterior end of the embryo.

129 ioning the viral genome to daughter cells in dividing cells; avoiding recognition by the immune syste

130 d CeGrip-1 that are centrosome components in dividing cells become localized to the apical membrane,

131 termined that LSD1 (1) is expressed in early dividing cells before OR expression and neuronal maturat

132 These studies reveal how symmetrically dividing cells both exploit and conform to tissue organi

133 onfined RhoA-GTP at the equatorial cortex of dividing cells, both the target specificity of Mgc's GAP

134 ust alter not only proteins intrinsic to the dividing cell but also their interacting partners on nei

135 death via mitotic arrest applies to rapidly dividing cells but cannot explain MTA activity in slowly

136 erentially taken up by arrested and actively dividing cells, but PET measures only aggregate uptake b

137 merases are essential for DNA replication in dividing cells, but their genomic targets and function i

138 g bipolarization, it ultimately benefits the dividing cell by promoting robust kinetochore attachment

139 dividing cells to be distinguished from non-dividing cells by a greater than two-fold increase in ce

140 ontractile actomyosin ring at the equator of dividing cells by activating the RhoGEF Pebble.

141 Cytokinesis physically separates dividing cells by forming a contractile actomyosin ring.

142 ivision and directly results in the death of dividing cells by reducing the levels of an essential re

143 tivation is co-ordinated to cell division in dividing cells by specific interactions that occur withi

144 Dividing cells called neoblasts contain pluripotent stem

145 ive tissue turnover because of the action of dividing cells called neoblasts.

146 Even symmetrically dividing cells can then by chance produce daughters with

147 fore, SAMHD1 expression, particularly in non-dividing cells, can restrict retroviral infections such

148 ty leading to incorrect chromosome number in dividing cells-can arise from defects in centrosome dupl

149 In actively dividing cells, centrioles establish the bipolar mitotic

150 In dividing cells, chromosome duplication once per generati

151 NK4a)-expressing cells are found adjacent to dividing cells, consistent with paracrine interaction.

152 During development, dividing cells control the position of the spindle to de

153 The majority of dividing cells corresponded to biciliated Ecc cells.

154 d it is not clear how a drug that only kills dividing cells could promote tumor regression.

155 In dividing cells, cytoplasmic dilution is the dominant rou

156 In dividing cells, depolymerizing spindle microtubules move

157 th in Arabidopsis thaliana by defining where dividing cells, derived from stem cells of the root meri

158 Dividing cells detach from the surrounding matrix and in

159 For example, many asymmetrically dividing cells differentially specify microtubule behavi

160 In dividing cells, DNA replication occurs in a precise orde

161 The fastest dividing cells doubled in less than 1 hour.

162 Here we identify long-lived proteins in dividing cells during aging using the budding yeast, Sac

163 vivo tracking and cell fate analyses of all dividing cells during lateral line hair cell regeneratio

164 Dividing cells embedded in fibrous matrices remained anc

165 s localized to cell plates in all classes of dividing cells examined.

166 AID protein was functional because AID(+) dividing cells exhibited more double-stranded DNA breaks

167 rt long-term expression of transgenes in non-dividing cells, exhibiting a decreased risk of insertion

168 Growing and dividing cells expand their PG layer by using membrane-a

169 ce intensities in subpopulations of live and dividing cells exposed or not exposed to different dosag

170 Using time-lapse microscopy of growing and dividing cells expressing a gfp-minD fusion, we show tha

171 Embryos and tumors are both masses of dividing cells expressing foreign Ags, but they are not

172 driven by Adr protects the peptidoglycan of dividing cells from cleavage by the major autolysin LytA

173 As the number of slow-dividing cells grows, their cycling-rate increases, even

174 somatic cell nuclei appeared normal, whereas dividing cells had abnormal nuclear envelope and chromat

175 However, the dividing cells had high mRNA levels for genes regulated

176 of organelle partitioning in asymmetrically dividing cells has provided insights into the mechanisms

177 Previous studies in dividing cells have shown that mTORC1 blocks autophagy t

178 To maintain a constant cell size, dividing cells have to coordinate cell-cycle events with

179 a potential benefit and liability to rapidly dividing cells; however, the precise post-translational

180 suggest that, unlike radiation, which kills dividing cells, hyperthermia-induced cell death affects

181 tituent cell types, including progenitor and dividing cells, immature granule cells, astrocytes, olig

182 al images of the chemical composition of the dividing cell in terms of water, proteins, DNAP (a mixtu

183 e duration of leaf elongation by maintaining dividing cells in a proliferative, undifferentiated stat

184 nd mCHG are selectively retained in actively dividing cells in culture, whereas mCHH is depleted.

185 ing epigenetic information in asymmetrically dividing cells in multicellular organisms.

186 zed to the centrosome and mitotic spindle of dividing cells in multiple cell lines, including MDCK, m

187 transcriptionally profiled dividing and non-dividing cells in regenerating stump tissues, as well as

188 micentins assemble at the cleavage furrow of dividing cells in the C. elegans germline and in preimpl

189 suggests that the vast majority of postnatal dividing cells in the central canal are Ecc cells and th

190 Clonal analysis of L3 Tr2 revealed that dividing cells in the dorsal trunk, dorsal branch and tr

191 Cilia are found on most non-dividing cells in the human body and, when faulty, cause

192 most of which was unbound) were found within dividing cells in the root tip cell proliferation zone.

193 ctions in microvascular density and actively dividing cells in the tumor sections after treatment in

194 LeuCAG3'tsRNA, induces apoptosis in rapidly dividing cells in vitro and in a patient-derived orthoto

195 robust DNA knock-in in both dividing and non-dividing cells in vitro and, more importantly, in vivo (

196 n to repress early meiosis-specific genes in dividing cells, in mitotic repression of meiosis-specifi

197 hich results in an increase in the number of dividing cells including transit-amplifying cells and ne

198 sequences to the chromosome ends in actively dividing cells, including 90% of all cancer cells.

199 AB8A causes centrosomal cohesion deficits in dividing cells, including in peripheral patient-derived

200 In rapidly dividing cells, including the majority of human cancers,

201 ing in both asymmetrically and symmetrically dividing cells, independent of its function in spindle p

202 nce correlation spectroscopy measurements in dividing cells indicated that a slow-diffusing, possibly

203 lves efficient and accurate splitting of the dividing cell into two separate entities.

204 ing the levels of telomerase in continuously dividing cells is important for understanding how much t

205 The data indicate that YycG activity in non-dividing cells is suppressed by its interaction with Yyc

206 es of Xenopus laevis, as an example of a non-dividing cell, is exclusive to the nuclear pore complex

207 hich leads to the physical separation of two dividing cells, is normally restrained until after nucle

208 In dividing cells, its complex architecture not only influe

209 itotic behavior in ureteric bud tips whereby dividing cells leave the epithelium for the lumen, retai

210 the thymidine analog BrdU into the genes of dividing cells makes the fate of postmitotic neurons mor

211 been considered to be largely restricted to dividing cells, making it challenging to apply the techn

212 The mechanism of targeting stable dividing cells may have implications for the treatment o

213 How dividing cells monitor the effective transmission of gen

214 repair of DNA lesions is a crucial task that dividing cells must actively perform to maintain genome

215 Dividing cells must balance the maintenance of genome in

216 Continuously dividing cells must be protected from telomeric and nont

217 They surround a group of slowly dividing cells named the quiescent center (QC), and, tog

218 inal step of cytokinesis, termed abscission, dividing cells need to ensure that the cleavage plane is

219 expression of ECT2, ECT3 and ECT4 in rapidly dividing cells of organ primordia.

220 In dividing cells of the mammalian skin, planar cell polari

221 -dependent cell death pathway in the rapidly dividing cells of the mouse embryo.

222 Dividing cells or CD45-staining cells were not detected

223 long-lived proteins exist in asymmetrically dividing cells or whether they are involved in aging.

224 The presence of dividing cells peaks in the CC lining on postnatal day 8

225 lows HVS-based vectors to stably transduce a dividing cell population and provide sustained transgene

226 asymmetrically in an otherwise symmetrically dividing cell population just upstream of cell fate dete

227 s may reduce cancer risk by partitioning the dividing cell populations into lineages comprising infre

228 ystem but maintain replication competence in dividing cell populations, such as those found in brain

229 ynthesis enzyme uniquely enriched in rapidly dividing cell populations.

230 ke reflect changes in the number of actively dividing cells, provided other parameters remain the sam

231 r simulations predict that the location of a dividing cell, rather than the orientation of the divisi

232 Dividing cells rely on the "conditionally essential" ami

233 e in trans, Vangl2 proteins intrinsic to the dividing cell remain associated with the plasma membrane

234 Dividing cells reorganize their microtubule cytoskeleton

235 nd promote wound healing, whereas frequently-dividing cells reside outside the JZ, preferentially ren

236 n of the overall sterol composition of young dividing cells reversibly impaired the PD localization o

237 In dividing cells, ribosomes accumulate on both sides of th

238 pathway is primarily restricted to actively dividing cells (S/G2-phase) and its efficiency for the i

239 ii) the increased metabolic needs of rapidly dividing cells serve as an evolutionary pressure for the

240 ated MreCD(Spn) to the equators and septa of dividing cells, similarly to the PBPs and PG pentapeptid

241 V-1) contributes to viral replication in non-dividing cells, specifically those of the myeloid lineag

242 low dNTP concentrations, but not in rapidly dividing cells such as cancer cells, which contain high

243 mportant in the microenvironment of actively dividing cells, such as cancer cells - disrupts the long

244 prolonged absence of telomerase activity in dividing cells, telomeres eventually become critically s

245 HEK293 cells are the only dividing cells tested that fully support the replication

246 rgrowth by increasing the number of actively dividing cells that accumulate high levels of phosphoryl

247 We also report the association of KRT13 with dividing cells that are reminiscent of previously descri

248 Here, we study mobility across dividing cells that contain densely packed, dynamic micr

249 st time a GEF controlling Rac1 activation in dividing cells that counteracts MgcRacGAP function in cy

250 repeated initiation of meristems, regions of dividing cells that give rise to new organs.

251 neration requires neoblasts, a population of dividing cells that has been studied for over a century.

252 erentiation, nonhuman origins, or the use of dividing cells that have neuropotential but lack neurona

253 chemical assembly hierarchy when observed in dividing cells that lack more basal components [3].

254 In symmetrically dividing cells the nascent transcription rate increases

255 In a population of dividing cells, the competition between viral genomes pr

256 In many asymmetrically dividing cells, the microtubule-organizing centers (MTOC

257 vo and in vitro data reveals that in rapidly dividing cells there are vastly fewer structured mRNA re

258 ition is the short-range elimination of slow-dividing cells through apoptosis when confronted with a

259 er lentiviruses mediate the infection of non-dividing cells through the ability of the capsid protein

260 idine (BrdU) was given systemically to label dividing cells throughout the experiment.

261 ee, focus-free information rich images allow dividing cells to be distinguished from non-dividing cel

262 on the ends of chromosomes, allowing rapidly dividing cells to proliferate while avoiding senescence

263 Genomes are transmitted faithfully from dividing cells to their offspring.

264 the desiccation sensitivity of exponentially dividing cells to understand the stresses imposed by des

265 from bundled arrays, which are prominent in dividing cells, to transverse orientations typically obs

266 roblem-positioning of the cleavage furrow in dividing cells-to explain how and why DE and AB models a

267 In actively dividing cells, translational repression was followed by

268 ortin(+) A cells were the second-most common dividing cell type in the V-SVZ and had a T(C) of 18 h a

269 at might be in place in other asymmetrically dividing cell types.

270 cancers to meet the folate demand of rapidly dividing cells under low folate conditions.

271 However, the aging process also occurs in dividing cells undergoing repeated asymmetric divisions.

272 B-GFP expressed at E9.5 to become diluted in dividing cells until the young adult stage, we determine

273 Mitotically dividing cells use a surveillance mechanism, the spindle

274 eplication defect of a virus lacking UL97 in dividing cells, validating this explanation.

275 plants instead synthesize and assemble a new dividing cell wall to separate newly formed daughter cel

276 The identity of dividing cells was determined by 3D ultrastructural reco

277 The number of dividing cells was higher in male rNPCs compared to fema

278 cal cell division, the proportion of apical (dividing) cells was quantified and telomere length, telo

279 Although expansions can accrue in non-dividing cells, we also show that cell cycle arrest is n

280 Importantly, the rates of expansion in non-dividing cells were at least as high as those of prolife

281 Dividing cells were found at the base of neuronal column

282 roxide, an effect that was enhanced when the dividing cells were treated with salicylic acid.

283 approach has been mainly applied to rapidly dividing cells where translation is active and large amo

284 s is in contrast to previous observations in dividing cells, where P-TEFb can be regulated by its seq

285 for the de novo establishment of H3K27me3 in dividing cells, whereas PRC2-Ezh1 is required for its ma

286 ponsible for Acm2 targeting to the septum of dividing cells, whereas the AST domain and its O-glycosy

287 e studies of heterogeneity among growing and dividing cells, whether in microbes or in differentiatin

288 module for selective gene expression in non-dividing cells, which allows us to radically alter popul

289 nt tools are inefficient, especially for non-dividing cells, which compose most adult tissues.

290 First, Tol mobilises Pal molecules in dividing cells, which otherwise diffuse very slowly due

291 therapeutics nonselectively kill all rapidly dividing cells, which produces numerous side effects.

292 Whether dividing cells, which temporarily reduce their attachmen

293 resent in poorly differentiated and actively dividing cells, while Ezh1 associates with PRC2 in all c

294 Mechanistically, IL-27 endowed rapidly dividing cells with IRF1, a transcription factor that wa

295 s, F-actin levels are decreased in ICBs, and dividing cells with lagging chromatin become binucleated

296 In non-dividing cells with lengths increased to 10 times normal

297 endent fashion, allowing isolation of slowly dividing cells with retained nuclear GFP signal.

298 tatic cell numbers by matching the number of dividing cells with the number of dying cells.

299 intercellular Celsr1 complexes that connect dividing cells with their neighbors remain intact during

300 Treatment of dividing cells with these compounds induced DNA damage a