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1 chronic clinical signs of toxic exposure to domoic acid.
2 status epilepticus when naturally exposed to domoic acid.
3 , but not in animals treated with 0.75 mg/kg domoic acid.
4 not 24 or 48 h after injection of 3.0 mg/kg domoic acid.
5 d receptor levels after sub-seizure doses of domoic acid (0-3.0 mg/kg) in rats using [3H]PK-11195 aut
8 iverse neurotoxicants including kainic acid, domoic acid, 3-nitropropionic acid, Fluoro-Gold and ison
9 lides can increase photodegradation rates of domoic acid, a marine algal toxin, and dimethyl sulfide,
10 that naturally develop TLE after exposure to domoic acid, a neurotoxin that enters the marine food ch
13 glc decreased in entorhinal cortex following domoic acid administration with or without convulsions.
15 classic excitotoxic neurotoxins kainic acid, domoic acid, and NMDA; the therapeutic glutamate analog
17 lifornianus) exposed to the algal neurotoxin domoic acid are treated in veterinary rehabilitation cen
18 structure of the prenyltransferase found in domoic acid biosynthesis, DabA, and show distinct active
19 onfirm that during excitotoxicity induced by domoic acid, calcineurin-Bcl-2 and calcineurin-1,4,5-ino
22 pid differentiation between the marine toxin domoic acid (DA) and its structural analog kainic acid (
27 was present and low levels of the neurotoxin domoic acid (DA) were detected in nearly all tested anim
28 This bloom was associated with production of domoic acid (DA), a neurotoxin that was also detected in
31 Ocean (66 degrees S) contain the neurotoxin domoic acid (DA), associated with the diatom Pseudo-nitz
32 ups: saxitoxin (STX), okadaic acid (OA), and domoic acid (DA), for PSP, DSP, and ASP, respectively.
33 ckish, and freshwater environments including domoic acid (DA), okadaic acid (OA, and analogues), saxi
35 posure of zebrafish embryos to the HAB toxin domoic acid (DomA) causes myelin defects, loss of reticu
36 life exposure to low levels of the HAB toxin domoic acid (DomA) produces long-lasting behavioral defi
37 echanisms in modulating the neurotoxicity of domoic acid (DomA), by using cerebellar granule neurons
47 n circuits by inducing convulsions, and that domoic acid-induced convulsions cause chronic effects on
50 ]quinoxaline-7-sulfonamide and reproduced by domoic acid microinjection, suggesting that the inductio
53 n during the biosynthesis of kainic acid and domoic acid, respectively, KabC can also produce a bicyc
56 y: other common marine toxins (okadaic acid, domoic acid, saxitoxin, brevetoxin-3, and yessotoxin) do
58 simplified analogues of the natural product domoic acid were designed, synthesized, and then charact
59 d with 1.5 and 3.0 mg/kg, but not 0.75 mg/kg domoic acid were significantly impaired in water maze pe